Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_33643 | 101 | 2.11 | Mlig455_027040 | Neo: - Age: Down-Up-Up |
FYN | Mlig455_027040 {REF} {Length: 3809} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=278.3]; Protein kinase domain [PF00069.27, score=160.7]; SH3 domain [PF00018.30, score=46.9]; Variant SH3 domain [PF14604.8, score=36.5]; SH2 domain [PF00017.26, score=34.2]; Variant SH3 domain [PF07653.19, score=28.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=330, Expect=3e-105]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=325, Expect=5e-104]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=324, Expect=3e-103]; ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=323, Expect=5e-103]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=318, Expect=2e-101]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=329, Expect=4e-105]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=325, Expect=2e-103]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=322, Expect=8e-103]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=317, Expect=8e-101]; ENSMUSG00000019779, Frk, fyn-related kinase, [Score=317, Expect=1e-100]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=333, Expect=3e-107]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=319, Expect=1e-101]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=413, Expect=3e-138]} {RNA1509_9783} {RNA1310_3966.1, RNA1509_9783} {RNA1509_9783, RNA815_6224} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.218 | 1.952 | 0.92274 | 1.00000 | |
RegionR2 | 0.661 | 1.952 | 0.42044 | 0.81204 | |
RegionR3 | -0.052 | 1.952 | 0.93430 | 1.00000 | |
RegionR4 | 0.017 | 1.952 | 0.98003 | 1.00000 | |
RegionR5 | -1.3 | 1.952 | 0.05723 | 0.20617 | |
RegionR6 | -0.176 | 1.952 | 0.79551 | 1.00000 | |
RegionR7 | -0.587 | 1.952 | 0.58191 | 1.00000 | |
RegionR8 | 1.655 | 1.952 | 0.07029 | 0.50806 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -4.287 | 1.952 | 0.49955 | 1.00000 | |
RegenerationR2 | -0.957 | 1.952 | 0.13772 | 0.56636 | |
RegenerationR3 | -1.244 | 1.952 | 0.10335 | 0.51025 | |
RegenerationR4 | -0.226 | 1.952 | 0.75833 | 0.97232 | |
RegenerationR5 | 0.366 | 1.952 | 0.61622 | 0.91678 | |
RegenerationR6 | -1.075 | 1.952 | 0.21348 | 0.55730 | |
RegenerationBL | -5.131 | 1.952 | 0.02181 | 0.16066 | |
RegenerationTP | -1.907 | 1.952 | 0.13252 | 0.54698 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_33643 | 101 | 2.11 | Mlig455_027040 | Neo: - Age: Down-Up-Up |
FYN | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_027040 {REF} {Length: 3809} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=278.3]; Protein kinase domain [PF00069.27, score=160.7]; SH3 domain [PF00018.30, score=46.9]; Variant SH3 domain [PF14604.8, score=36.5]; SH2 domain [PF00017.26, score=34.2]; Variant SH3 domain [PF07653.19, score=28.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=330, Expect=3e-105]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=325, Expect=5e-104]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=324, Expect=3e-103]; ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=323, Expect=5e-103]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=318, Expect=2e-101]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=329, Expect=4e-105]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=325, Expect=2e-103]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=322, Expect=8e-103]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=317, Expect=8e-101]; ENSMUSG00000019779, Frk, fyn-related kinase, [Score=317, Expect=1e-100]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=333, Expect=3e-107]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=319, Expect=1e-101]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=413, Expect=3e-138]} {RNA1509_9783} {RNA1310_3966.1, RNA1509_9783} {RNA1509_9783, RNA815_6224} |
2. | MligTC455_39673 | 301 | 6.27 | Mlig455_032019 | Neo: - Age: logFC(26M/2M)=-0.502 |
RAP2B | 1.655 | - | - | 0.704 | - | - | 0.951 | Mlig455_032019 {REF} {Length: 2377} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=185.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.2]; ADP-ribosylation factor family [PF00025.23, score=38.3]; RsgA GTPase [PF03193.18, score=26.7]; 50S ribosome-binding GTPase [PF01926.25, score=21.4]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.7]} {Human: ENSG00000181467, RAP2B, RAP2B, member of RAS oncogene family, [Score=214, Expect=4e-71]; ENSG00000127314, RAP1B, RAP1B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSG00000123728, RAP2C, RAP2C, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000116473, RAP1A, RAP1A, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000125249, RAP2A, RAP2A, member of RAS oncogene family, [Score=206, Expect=4e-68]} {Mouse: ENSMUSG00000051615, Rap2a, RAS related protein 2a, [Score=215, Expect=7e-72]; ENSMUSG00000036894, Rap2b, RAP2B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSMUSG00000052681, Rap1b, RAS related protein 1b, [Score=214, Expect=2e-71]; ENSMUSG00000050029, Rap2c, RAP2C, member of RAS oncogene family, [Score=209, Expect=2e-69]; ENSMUSG00000068798, Rap1a, RAS-related protein 1a, [Score=209, Expect=3e-69]} {Dmel: FBgn0004636, Rap1, Rap1 GTPase, [Score=208, Expect=4e-69]} {Celegans: WBGene00004308, rap-2, RAP homolog (Vertebrate Rap GTPase family), [RH, Score=222, Expect=1e-74]} {Smed: dd_Smed_v6_1239_0_1, dd_Smed_v6_1239_0_1, [Score=207, Expect=9e-69]} {RNA1509_19937} {RNA1310_3952} {RNA815_8102} |
3. | MligTC455_45858 | 91 | 1.89 | Mlig455_032522 | Neo: Int S/G2/M Age: logFC(26M/2M)=1.279 |
FARSB | 0.978 | - | - | 0.978 | - | - | - | Mlig455_032522 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: Phenylalanyl tRNA synthetase beta chain CLM domain [PF17759.3, score=165.5]; Phe-tRNA synthetase beta subunit B1 domain [PF18262.3, score=103.8]; tRNA synthetase B5 domain [PF03484.17, score=60.8]; B3/4 domain [PF03483.19, score=30.3]} {Human: ENSG00000116120, FARSB, phenylalanyl-tRNA synthetase subunit beta, [Score=566, Expect=0.0]} {Mouse: ENSMUSG00000026245, Farsb, phenylalanyl-tRNA synthetase, beta subunit, [Score=568, Expect=0.0]} {Dmel: FBgn0039175, beta-PheRS, Phenylalanyl-tRNA synthetase, beta-subunit, [Score=547, Expect=0.0]} {Celegans: WBGene00001498, fars-3, Phenylalanine--tRNA ligase beta subunit, [Score=525, Expect=0.0]} {Smed: dd_Smed_v6_2020_0_1, dd_Smed_v6_2020_0_1, [Score=409, Expect=6e-137]} {RNA1509_10740, RNA1509_43864} {RNA1310_12802, RNA1509_43864} {RNA1509_43864, RNA815_4058} |
4. | MligTC455_48298 | 55 | 1.14 | Mlig455_067985 | Neo: - Age: - |
0.978 | - | - | 0.978 | - | - | - | Mlig455_067985 {REF} {Length: 1658} {TRANSSPLICED} {Pfam: Centrosomin N-terminal motif 1 [PF07989.13, score=19.1]} {RNA1509_50908} {RNA1310_7799.1} {RNA815_38707} | |
5. | MligTC455_26512 | 128 | 2.67 | Mlig455_069089 | Neo: - Age: Up-Down-Down |
PRKDC | 0.969 | - | - | 0.969 | - | - | - | Mlig455_069089 {REF} {Length: 15905} {Pfam: NUC194 domain [PF08163.14, score=230.9]; DNA-PKcs, CC5 [PF19704.1, score=218.9]; Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=139.7]; FAT domain [PF02259.25, score=33.6]; FATC domain [PF02260.22, score=27.0]; DDE superfamily endonuclease [PF13358.8, score=24.7]; Helix-turn-helix domain [PF13518.8, score=22.8]} {Human: ENSG00000253729, PRKDC, protein kinase, DNA-activated, catalytic subunit, [Score=652, Expect=0.0]} {Mouse: ENSMUSG00000022672, Prkdc, protein kinase, DNA activated, catalytic polypeptide, [Score=624, Expect=1e-178]} {Dmel: FBgn0021796, Tor, Target of rapamycin, [Score=152, Expect=8e-36]} {Celegans: WBGene00002583, let-363, Target of rapamycin homolog, [Score=149, Expect=3e-35]} {Smed: dd_Smed_v6_8462_0_2, dd_Smed_v6_8462_0_2, [RH, Score=284, Expect=5e-76]} {RNA1509_11402, RNA1509_47977, RNA1509_60024} {RNA1310_372, RNA1509_47977, RNA1509_60024} {RNA1509_47977, RNA1509_60024, RNA815_3968} |
6. | MligTC455_26511 | 114 | 2.38 | Mlig455_052535 | Neo: - Age: Up-Down-Down |
PRKDC | 0.966 | - | - | 0.966 | - | - | - | Mlig455_052535 {REF} {Length: 9557} {Pfam: DNA-PKcs, CC5 [PF19704.1, score=168.6]; Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=141.2]; FAT domain [PF02259.25, score=34.5]; FATC domain [PF02260.22, score=28.3]} {Human: ENSG00000253729, PRKDC, protein kinase, DNA-activated, catalytic subunit, [Score=374, Expect=9e-104]} {Mouse: ENSMUSG00000022672, Prkdc, protein kinase, DNA activated, catalytic polypeptide, [Score=389, Expect=2e-108]} {Dmel: FBgn0021796, Tor, Target of rapamycin, [Score=152, Expect=3e-36]} {Celegans: WBGene00002583, let-363, Target of rapamycin homolog, [Score=149, Expect=1e-35]} {Smed: dd_Smed_v6_8462_0_1, dd_Smed_v6_8462_0_1, [RH, Score=284, Expect=2e-78]} {RNA1509_35967} {RNA1310_372} {RNA815_3968} |
7. | MligTC455_14105 | 81 | 1.7 | Mlig455_012934 | Neo: - Age: - |
TMBIM4 | 0.962 | - | - | 0.962 | - | - | - | Mlig455_012934 {REF} {Length: 2323} {TRANSSPLICED} {Pfam: Inhibitor of apoptosis-promoting Bax1 [PF01027.22, score=123.9]} {Human: ENSG00000155957, TMBIM4, transmembrane BAX inhibitor motif containing 4, [Score=138, Expect=3e-40]} {Mouse: ENSMUSG00000020225, Tmbim4, transmembrane BAX inhibitor motif containing 4, [Score=144, Expect=1e-42]} {Dmel: FBgn0013305, Nmda1, N-methyl-D-aspartate receptor-associated protein, [Score=92.8, Expect=2e-22]} {Celegans: WBGene00006479, tmbi-4, Transmembrane BAX inhibitor motif-containing protein 4, [Score=111, Expect=5e-30]} {Smed: dd_Smed_v6_1521_0_1, dd_Smed_v6_1521_0_1, [Score=171, Expect=9e-54]} {RNA1509_25696, RNA1509_49717} {RNA1310_47965.2, RNA1509_49717} {RNA1509_49717, RNA815_15216} |
8. | MligTC455_30688 | 71 | 1.47 | Mlig455_051436 | Neo: - Age: - |
0.962 | - | - | 0.962 | - | - | - | Mlig455_051436 {REF} {Length: 3301} {TRANSSPLICED} {RNA1509_47978} {RNA1310_16577.1, RNA1509_47978} {RNA1509_47978, RNA815_31875} | |
9. | MligTC455_11818 | 167 | 3.49 | Mlig455_064965 | Neo: - Age: Down-Up-Down |
TTC30B | 0.955 | - | - | 0.955 | - | - | - | Mlig455_064965 {REF} {Length: 2662} {Human: ENSG00000196659, TTC30B, tetratricopeptide repeat domain 30B, [Score=202, Expect=5e-62]; ENSG00000197557, TTC30A, tetratricopeptide repeat domain 30A, [Score=198, Expect=2e-60]} {Mouse: ENSMUSG00000075271, Ttc30a1, tetratricopeptide repeat domain 30A1, [Score=205, Expect=4e-63]; ENSMUSG00000075272, Ttc30a2, tetratricopeptide repeat domain 30A2, [Score=202, Expect=5e-62]; ENSMUSG00000075273, Ttc30b, tetratricopeptide repeat domain 30B, [Score=201, Expect=8e-62]} {Dmel: FBgn0032470, CG5142, [Score=94.4, Expect=6e-23]} {Celegans: WBGene00001117, dyf-1, Tetratricopeptide repeat protein 30 homolog, [Score=138, Expect=8e-39]} {Smed: dd_Smed_v6_8798_0_1, dd_Smed_v6_8798_0_1, [Score=224, Expect=1e-70]} {RNA1509_15421} {RNA1310_6112} {RNA815_1970} |