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Results for MligTC455_33643

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_33643 101 2.11 Mlig455_027040

Neo: -

Age: Down-Up-Up

FYN Mlig455_027040 {REF} {Length: 3809} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=278.3]; Protein kinase domain [PF00069.27, score=160.7]; SH3 domain [PF00018.30, score=46.9]; Variant SH3 domain [PF14604.8, score=36.5]; SH2 domain [PF00017.26, score=34.2]; Variant SH3 domain [PF07653.19, score=28.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=330, Expect=3e-105]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=325, Expect=5e-104]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=324, Expect=3e-103]; ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=323, Expect=5e-103]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=318, Expect=2e-101]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=329, Expect=4e-105]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=325, Expect=2e-103]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=322, Expect=8e-103]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=317, Expect=8e-101]; ENSMUSG00000019779, Frk, fyn-related kinase, [Score=317, Expect=1e-100]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=333, Expect=3e-107]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=319, Expect=1e-101]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=413, Expect=3e-138]} {RNA1509_9783} {RNA1310_3966.1, RNA1509_9783} {RNA1509_9783, RNA815_6224}

Cumulative graph for MligTC455_33643

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.218 1.952 0.92274 1.00000
RegionR2 0.661 1.952 0.42044 0.81204
RegionR3 -0.052 1.952 0.93430 1.00000
RegionR4 0.017 1.952 0.98003 1.00000
RegionR5 -1.3 1.952 0.05723 0.20617
RegionR6 -0.176 1.952 0.79551 1.00000
RegionR7 -0.587 1.952 0.58191 1.00000
RegionR8 1.655 1.952 0.07029 0.50806

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -4.287 1.952 0.49955 1.00000
RegenerationR2 -0.957 1.952 0.13772 0.56636
RegenerationR3 -1.244 1.952 0.10335 0.51025
RegenerationR4 -0.226 1.952 0.75833 0.97232
RegenerationR5 0.366 1.952 0.61622 0.91678
RegenerationR6 -1.075 1.952 0.21348 0.55730
RegenerationBL -5.131 1.952 0.02181 0.16066
RegenerationTP -1.907 1.952 0.13252 0.54698


Genes with expression patterns similar to MligTC455_33643

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_33643 101 2.11 Mlig455_027040

Neo: -

Age: Down-Up-Up

FYN 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_027040 {REF} {Length: 3809} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=278.3]; Protein kinase domain [PF00069.27, score=160.7]; SH3 domain [PF00018.30, score=46.9]; Variant SH3 domain [PF14604.8, score=36.5]; SH2 domain [PF00017.26, score=34.2]; Variant SH3 domain [PF07653.19, score=28.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=330, Expect=3e-105]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=325, Expect=5e-104]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=324, Expect=3e-103]; ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=323, Expect=5e-103]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=318, Expect=2e-101]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=329, Expect=4e-105]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=325, Expect=2e-103]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=322, Expect=8e-103]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=317, Expect=8e-101]; ENSMUSG00000019779, Frk, fyn-related kinase, [Score=317, Expect=1e-100]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=333, Expect=3e-107]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=319, Expect=1e-101]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=413, Expect=3e-138]} {RNA1509_9783} {RNA1310_3966.1, RNA1509_9783} {RNA1509_9783, RNA815_6224}
2. MligTC455_39673 301 6.27 Mlig455_032019

Neo: -

Age: logFC(26M/2M)=-0.502

RAP2B 1.655 - - 0.704 - - 0.951 Mlig455_032019 {REF} {Length: 2377} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=185.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.2]; ADP-ribosylation factor family [PF00025.23, score=38.3]; RsgA GTPase [PF03193.18, score=26.7]; 50S ribosome-binding GTPase [PF01926.25, score=21.4]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.7]} {Human: ENSG00000181467, RAP2B, RAP2B, member of RAS oncogene family, [Score=214, Expect=4e-71]; ENSG00000127314, RAP1B, RAP1B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSG00000123728, RAP2C, RAP2C, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000116473, RAP1A, RAP1A, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000125249, RAP2A, RAP2A, member of RAS oncogene family, [Score=206, Expect=4e-68]} {Mouse: ENSMUSG00000051615, Rap2a, RAS related protein 2a, [Score=215, Expect=7e-72]; ENSMUSG00000036894, Rap2b, RAP2B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSMUSG00000052681, Rap1b, RAS related protein 1b, [Score=214, Expect=2e-71]; ENSMUSG00000050029, Rap2c, RAP2C, member of RAS oncogene family, [Score=209, Expect=2e-69]; ENSMUSG00000068798, Rap1a, RAS-related protein 1a, [Score=209, Expect=3e-69]} {Dmel: FBgn0004636, Rap1, Rap1 GTPase, [Score=208, Expect=4e-69]} {Celegans: WBGene00004308, rap-2, RAP homolog (Vertebrate Rap GTPase family), [RH, Score=222, Expect=1e-74]} {Smed: dd_Smed_v6_1239_0_1, dd_Smed_v6_1239_0_1, [Score=207, Expect=9e-69]} {RNA1509_19937} {RNA1310_3952} {RNA815_8102}
3. MligTC455_45858 91 1.89 Mlig455_032522

Neo: Int S/G2/M

Age: logFC(26M/2M)=1.279

FARSB 0.978 - - 0.978 - - - Mlig455_032522 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: Phenylalanyl tRNA synthetase beta chain CLM domain [PF17759.3, score=165.5]; Phe-tRNA synthetase beta subunit B1 domain [PF18262.3, score=103.8]; tRNA synthetase B5 domain [PF03484.17, score=60.8]; B3/4 domain [PF03483.19, score=30.3]} {Human: ENSG00000116120, FARSB, phenylalanyl-tRNA synthetase subunit beta, [Score=566, Expect=0.0]} {Mouse: ENSMUSG00000026245, Farsb, phenylalanyl-tRNA synthetase, beta subunit, [Score=568, Expect=0.0]} {Dmel: FBgn0039175, beta-PheRS, Phenylalanyl-tRNA synthetase, beta-subunit, [Score=547, Expect=0.0]} {Celegans: WBGene00001498, fars-3, Phenylalanine--tRNA ligase beta subunit, [Score=525, Expect=0.0]} {Smed: dd_Smed_v6_2020_0_1, dd_Smed_v6_2020_0_1, [Score=409, Expect=6e-137]} {RNA1509_10740, RNA1509_43864} {RNA1310_12802, RNA1509_43864} {RNA1509_43864, RNA815_4058}
4. MligTC455_48298 55 1.14 Mlig455_067985

Neo: -

Age: -

0.978 - - 0.978 - - - Mlig455_067985 {REF} {Length: 1658} {TRANSSPLICED} {Pfam: Centrosomin N-terminal motif 1 [PF07989.13, score=19.1]} {RNA1509_50908} {RNA1310_7799.1} {RNA815_38707}
5. MligTC455_26512 128 2.67 Mlig455_069089

Neo: -

Age: Up-Down-Down

PRKDC 0.969 - - 0.969 - - - Mlig455_069089 {REF} {Length: 15905} {Pfam: NUC194 domain [PF08163.14, score=230.9]; DNA-PKcs, CC5 [PF19704.1, score=218.9]; Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=139.7]; FAT domain [PF02259.25, score=33.6]; FATC domain [PF02260.22, score=27.0]; DDE superfamily endonuclease [PF13358.8, score=24.7]; Helix-turn-helix domain [PF13518.8, score=22.8]} {Human: ENSG00000253729, PRKDC, protein kinase, DNA-activated, catalytic subunit, [Score=652, Expect=0.0]} {Mouse: ENSMUSG00000022672, Prkdc, protein kinase, DNA activated, catalytic polypeptide, [Score=624, Expect=1e-178]} {Dmel: FBgn0021796, Tor, Target of rapamycin, [Score=152, Expect=8e-36]} {Celegans: WBGene00002583, let-363, Target of rapamycin homolog, [Score=149, Expect=3e-35]} {Smed: dd_Smed_v6_8462_0_2, dd_Smed_v6_8462_0_2, [RH, Score=284, Expect=5e-76]} {RNA1509_11402, RNA1509_47977, RNA1509_60024} {RNA1310_372, RNA1509_47977, RNA1509_60024} {RNA1509_47977, RNA1509_60024, RNA815_3968}
6. MligTC455_26511 114 2.38 Mlig455_052535

Neo: -

Age: Up-Down-Down

PRKDC 0.966 - - 0.966 - - - Mlig455_052535 {REF} {Length: 9557} {Pfam: DNA-PKcs, CC5 [PF19704.1, score=168.6]; Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=141.2]; FAT domain [PF02259.25, score=34.5]; FATC domain [PF02260.22, score=28.3]} {Human: ENSG00000253729, PRKDC, protein kinase, DNA-activated, catalytic subunit, [Score=374, Expect=9e-104]} {Mouse: ENSMUSG00000022672, Prkdc, protein kinase, DNA activated, catalytic polypeptide, [Score=389, Expect=2e-108]} {Dmel: FBgn0021796, Tor, Target of rapamycin, [Score=152, Expect=3e-36]} {Celegans: WBGene00002583, let-363, Target of rapamycin homolog, [Score=149, Expect=1e-35]} {Smed: dd_Smed_v6_8462_0_1, dd_Smed_v6_8462_0_1, [RH, Score=284, Expect=2e-78]} {RNA1509_35967} {RNA1310_372} {RNA815_3968}
7. MligTC455_14105 81 1.7 Mlig455_012934

Neo: -

Age: -

TMBIM4 0.962 - - 0.962 - - - Mlig455_012934 {REF} {Length: 2323} {TRANSSPLICED} {Pfam: Inhibitor of apoptosis-promoting Bax1 [PF01027.22, score=123.9]} {Human: ENSG00000155957, TMBIM4, transmembrane BAX inhibitor motif containing 4, [Score=138, Expect=3e-40]} {Mouse: ENSMUSG00000020225, Tmbim4, transmembrane BAX inhibitor motif containing 4, [Score=144, Expect=1e-42]} {Dmel: FBgn0013305, Nmda1, N-methyl-D-aspartate receptor-associated protein, [Score=92.8, Expect=2e-22]} {Celegans: WBGene00006479, tmbi-4, Transmembrane BAX inhibitor motif-containing protein 4, [Score=111, Expect=5e-30]} {Smed: dd_Smed_v6_1521_0_1, dd_Smed_v6_1521_0_1, [Score=171, Expect=9e-54]} {RNA1509_25696, RNA1509_49717} {RNA1310_47965.2, RNA1509_49717} {RNA1509_49717, RNA815_15216}
8. MligTC455_30688 71 1.47 Mlig455_051436

Neo: -

Age: -

0.962 - - 0.962 - - - Mlig455_051436 {REF} {Length: 3301} {TRANSSPLICED} {RNA1509_47978} {RNA1310_16577.1, RNA1509_47978} {RNA1509_47978, RNA815_31875}
9. MligTC455_11818 167 3.49 Mlig455_064965

Neo: -

Age: Down-Up-Down

TTC30B 0.955 - - 0.955 - - - Mlig455_064965 {REF} {Length: 2662} {Human: ENSG00000196659, TTC30B, tetratricopeptide repeat domain 30B, [Score=202, Expect=5e-62]; ENSG00000197557, TTC30A, tetratricopeptide repeat domain 30A, [Score=198, Expect=2e-60]} {Mouse: ENSMUSG00000075271, Ttc30a1, tetratricopeptide repeat domain 30A1, [Score=205, Expect=4e-63]; ENSMUSG00000075272, Ttc30a2, tetratricopeptide repeat domain 30A2, [Score=202, Expect=5e-62]; ENSMUSG00000075273, Ttc30b, tetratricopeptide repeat domain 30B, [Score=201, Expect=8e-62]} {Dmel: FBgn0032470, CG5142, [Score=94.4, Expect=6e-23]} {Celegans: WBGene00001117, dyf-1, Tetratricopeptide repeat protein 30 homolog, [Score=138, Expect=8e-39]} {Smed: dd_Smed_v6_8798_0_1, dd_Smed_v6_8798_0_1, [Score=224, Expect=1e-70]} {RNA1509_15421} {RNA1310_6112} {RNA815_1970}

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