M. lignano Tomo-Seq
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Results for MligTC455_35745

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_35745 3964 82.58 Mlig455_060880

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.298

 TECR Mlig455_060880 {REF} {Length: 1263} {TRANSSPLICED} {Pfam: 3-oxo-5-alpha-steroid 4-dehydrogenase [PF02544.18, score=94.2]} {Human: ENSG00000099797, TECR, trans-2,3-enoyl-CoA reductase, [RH, Score=334, Expect=1e-114]} {Mouse: ENSMUSG00000031708, Tecr, trans-2,3-enoyl-CoA reductase, [RH, Score=330, Expect=2e-113]} {Dmel: FBgn0035471, Sc2, [RH, Score=345, Expect=4e-119]} {Celegans: WBGene00000198, art-1, Probable very-long-chain enoyl-CoA reductase art-1, [RH, Score=334, Expect=6e-115]} {Smed: dd_Smed_v6_2085_0_1, dd_Smed_v6_2085_0_1, [RH, Score=333, Expect=6e-115]} {RNA1509_18659, RNA1509_19947, RNA1509_33959, RNA1509_37614, RNA1509_9226} {RNA1310_26993, RNA1509_18659, RNA1509_19947, RNA1509_33959, RNA1509_37614, RNA1509_9226} {RNA1509_18659, RNA1509_19947, RNA1509_33959, RNA1509_37614, RNA1509_9226, RNA815_11767}

Cumulative graph for MligTC455_35745

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.693 6.506 0.20134 0.83848
RegionR2 -0.457 6.506 0.05575 0.28325
RegionR3 0.457 6.506 0.01286 0.17968
RegionR4 0.813 6.506 0.00016 0.00238
RegionR5 0.877 6.506 0.00000 0.00001
RegionR6 0.426 6.506 0.02351 0.27841
RegionR7 -0.516 6.506 0.04762 0.41953
RegionR8 -0.907 6.506 0.00873 0.17431

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.71 6.506 0.28937 0.98735
RegenerationR2 -0.195 6.506 0.34302 0.77719
RegenerationR3 -0.067 6.506 0.74524 0.96255
RegenerationR4 0.084 6.506 0.69347 0.95084
RegenerationR5 -0.082 6.506 0.66991 0.94065
RegenerationR6 0.199 6.506 0.33519 0.68133
RegenerationBL 0.739 6.506 0.00214 0.03781
RegenerationTP 0.178 6.506 0.55408 0.93597


Genes with expression patterns similar to MligTC455_35745

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_35745 3964 82.58 Mlig455_060880

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.298

 TECR 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_060880 {REF} {Length: 1263} {TRANSSPLICED} {Pfam: 3-oxo-5-alpha-steroid 4-dehydrogenase [PF02544.18, score=94.2]} {Human: ENSG00000099797, TECR, trans-2,3-enoyl-CoA reductase, [RH, Score=334, Expect=1e-114]} {Mouse: ENSMUSG00000031708, Tecr, trans-2,3-enoyl-CoA reductase, [RH, Score=330, Expect=2e-113]} {Dmel: FBgn0035471, Sc2, [RH, Score=345, Expect=4e-119]} {Celegans: WBGene00000198, art-1, Probable very-long-chain enoyl-CoA reductase art-1, [RH, Score=334, Expect=6e-115]} {Smed: dd_Smed_v6_2085_0_1, dd_Smed_v6_2085_0_1, [RH, Score=333, Expect=6e-115]} {RNA1509_18659, RNA1509_19947, RNA1509_33959, RNA1509_37614, RNA1509_9226} {RNA1310_26993, RNA1509_18659, RNA1509_19947, RNA1509_33959, RNA1509_37614, RNA1509_9226} {RNA1509_18659, RNA1509_19947, RNA1509_33959, RNA1509_37614, RNA1509_9226, RNA815_11767}
2. MligTC455_49113 8318 173.3 Mlig455_018424

Neo: -

Age: -

Regeneration-upregulated BL: 1.412

Regeneration-enriched BL: 1.412

 HADHA 3.359 - - 0.818 0.972 0.823 0.746 Mlig455_018424 {REF} {Length: 2972} {TRANSSPLICED} {Pfam: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain [PF02737.20, score=193.1]; Enoyl-CoA hydratase/isomerase [PF00378.22, score=134.0]; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain [PF00725.24, score=106.5]; Enoyl-CoA hydratase/isomerase [PF16113.7, score=74.7]} {Human: ENSG00000084754, HADHA, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha, [RH, Score=831, Expect=0.0]} {Mouse: ENSMUSG00000025745, Hadha, hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit, [RH, Score=813, Expect=0.0]} {Dmel: FBgn0028479, Mtpalpha, Mitochondrial trifunctional protein alpha subunit, [RH, Score=822, Expect=0.0]} {Celegans: WBGene00020347, ech-1.2, Enoyl-CoA Hydratase, [RH, Score=752, Expect=0.0]} {Smed: dd_Smed_v6_863_0_1, dd_Smed_v6_863_0_1, [RH, Score=888, Expect=0.0]} {RNA1509_430, RNA1509_6723} {RNA1310_5592.1, RNA1509_430, RNA1509_6723} {RNA1509_430, RNA1509_6723, RNA815_1687.1}
3. MligTC455_27350 318 6.63 Mlig455_022459

Neo: -

Age: -

 1.8 - - - 0.964 0.836 - Mlig455_022459 {REF} {Length: 3884} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=51.8]; Phage integrase family [PF00589.24, score=37.0]; Phage integrase, N-terminal SAM-like domain [PF13495.8, score=23.8]; Phage integrase, N-terminal SAM-like domain [PF02899.19, score=22.4]} {RNA1509_3317} {RNA1310_1684} {RNA815_1380.1}
4. MligTC455_27352 306 6.37 Mlig455_018411

Neo: -

Age: Up-Down-Down

 1.765 - - - 0.956 0.809 - Mlig455_018411 {REF} {Length: 4225} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=51.7]} {RNA1509_12873, RNA1509_20908, RNA1509_31975, RNA1509_3317} {RNA1310_1684, RNA1509_12873, RNA1509_20908, RNA1509_31975, RNA1509_3317} {RNA1509_12873, RNA1509_20908, RNA1509_31975, RNA1509_3317, RNA815_1380.1}
5. MligTC455_27353 301 6.27 Mlig455_029175

Neo: -

Age: -

 1.759 - - - 0.964 0.795 - Mlig455_029175 {REF} {Length: 2029} {RNA1509_3317} {RNA1310_25634} {RNA815_29979}
6. MligTC455_26965 32675 680.72 Mlig455_018994, Mlig455_055709

Neo: Germline

Age: logFC(26M/2M)=0.206

 P4HB 0.958 - - - - 0.958 -

Mlig455_018994 {REF} {Length: 3271} {Pfam: Thioredoxin [PF00085.22, score=208.2]; Thioredoxin-like domain [PF13848.8, score=151.5]; Thioredoxin-like domain [PF13098.8, score=58.6]; Calsequestrin [PF01216.19, score=52.1]; OST3 / OST6 family, transporter family [PF04756.15, score=45.9]; Thioredoxin-like [PF13905.8, score=43.3]; ERp29, N-terminal domain [PF07912.15, score=42.6]; Thioredoxin-like [PF13899.8, score=42.6]; AhpC/TSA family [PF00578.23, score=35.2]; Redoxin [PF08534.12, score=31.1]; F plasmid transfer operon protein [PF13728.8, score=23.3]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [RH, Score=510, Expect=3e-178]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1}

Mlig455_055709 {REF} {Length: 3265} {Pfam: Thioredoxin [PF00085.22, score=208.2]; Thioredoxin-like domain [PF13848.8, score=151.5]; Thioredoxin-like domain [PF13098.8, score=58.6]; Calsequestrin [PF01216.19, score=52.1]; OST3 / OST6 family, transporter family [PF04756.15, score=45.9]; Thioredoxin-like [PF13905.8, score=43.3]; ERp29, N-terminal domain [PF07912.15, score=42.6]; Thioredoxin-like [PF13899.8, score=42.6]; AhpC/TSA family [PF00578.23, score=35.2]; Redoxin [PF08534.12, score=31.1]; F plasmid transfer operon protein [PF13728.8, score=23.3]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [RH, Score=510, Expect=3e-178]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1575, RNA1509_70} {RNA1310_2450.1, RNA1509_1575, RNA1509_70} {RNA1509_1575, RNA1509_70, RNA815_1453.1}

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