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Results for MligTC455_36202

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_36202 391 8.16 Mlig455_047412

Neo: -

Age: -

Region-enriched R4: 2.275/0.02192

 Mlig455_047412 {REF} {Length: 1289} {Pfam: Septum formation initiator [PF04977.17, score=26.2]; Homeobox associated leucine zipper [PF02183.20, score=23.7]; bZIP transcription factor [PF00170.23, score=20.9]; Cell division protein ZapB [PF06005.14, score=20.3]} {RNA1310_27421} {RNA815_13556}

Cumulative graph for MligTC455_36202

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.082 3.251 0.12299 0.71700
RegionR2 1.013 3.251 0.26745 0.65028
RegionR3 0.568 3.251 0.53980 1.00000
RegionR4 2.275 3.251 0.00260 0.02192
RegionR5 1.178 3.251 0.13303 0.37187
RegionR6 0.061 3.251 0.83162 1.00000
RegionR7 0.8 3.251 0.44670 1.00000
RegionR8 0.187 3.251 0.80058 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 5.652 3.251 0.24512 0.96633
RegenerationR2 0.237 3.251 0.61997 0.92329
RegenerationR3 0.231 3.251 0.68892 0.94386
RegenerationR4 -0.188 3.251 0.72055 0.96161
RegenerationR5 -0.104 3.251 0.84397 1.00000
RegenerationR6 0.852 3.251 0.17937 0.51375
RegenerationBL 0.914 3.251 0.16962 0.49397
RegenerationTP 1.174 3.251 0.11088 0.51219


Genes with expression patterns similar to MligTC455_36202

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_36202 391 8.16 Mlig455_047412

Neo: -

Age: -

Region-enriched R4: 2.275/0.02192

 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_047412 {REF} {Length: 1289} {Pfam: Septum formation initiator [PF04977.17, score=26.2]; Homeobox associated leucine zipper [PF02183.20, score=23.7]; bZIP transcription factor [PF00170.23, score=20.9]; Cell division protein ZapB [PF06005.14, score=20.3]} {RNA1310_27421} {RNA815_13556}
2. MligTC455_40801 425 8.85 Mlig455_003100, Mlig455_062789

Neo: -

Age: logFC(26M/2M)=-0.250

Region-enriched R2: 3.506/0.00053
Region-enriched R3: 2.405/0.00633

 MDH1B 2.558 - 0.827 - 0.773 - 0.958

Mlig455_003100 {REF} {Length: 4802} {Pfam: lactate/malate dehydrogenase, alpha/beta C-terminal domain [PF02866.20, score=53.0]} {Human: ENSG00000138400, MDH1B, malate dehydrogenase 1B, [Score=323, Expect=1e-102]} {Mouse: ENSMUSG00000025963, Mdh1b, malate dehydrogenase 1B, NAD (soluble), [Score=304, Expect=1e-95]} {Dmel: FBgn0262782, Mdh1, Malate dehydrogenase 1, [Score=107, Expect=3e-25]} {Celegans: WBGene00018491, mdh-1, Malate DeHydrogenase, [Score=98.2, Expect=4e-22]} {Smed: dd_Smed_v6_10200_0_1, dd_Smed_v6_10200_0_1, [Score=335, Expect=2e-106]} {RNA1509_47623, RNA1509_9622} {RNA1310_5189, RNA1509_47623} {RNA1509_47623, RNA815_3770}

Mlig455_062789 {REF} {Length: 2979} {Pfam: lactate/malate dehydrogenase, alpha/beta C-terminal domain [PF02866.20, score=52.9]} {Human: ENSG00000138400, MDH1B, malate dehydrogenase 1B, [Score=323, Expect=1e-102]} {Mouse: ENSMUSG00000025963, Mdh1b, malate dehydrogenase 1B, NAD (soluble), [Score=304, Expect=1e-95]} {Dmel: FBgn0262782, Mdh1, Malate dehydrogenase 1, [Score=105, Expect=2e-24]} {Celegans: WBGene00018491, mdh-1, Malate DeHydrogenase, [Score=97.8, Expect=5e-22]} {Smed: dd_Smed_v6_10200_0_1, dd_Smed_v6_10200_0_1, [RH, Score=337, Expect=1e-107]} {RNA1509_9622} {RNA1310_5189, RNA1509_9622} {RNA1509_9622, RNA815_3770}
3. MligTC455_41575 418 8.71 Mlig455_012538

Neo: -

Age: Down-Up-Down

 1.828 - - - 0.862 - 0.966 Mlig455_012538 {REF} {Length: 1233} {Pfam: EF hand [PF00036.34, score=47.8]; EF-hand domain pair [PF13499.8, score=46.4]; EF-hand domain [PF13405.8, score=44.3]; EF-hand domain pair [PF13833.8, score=26.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=24.4]; EF hand [PF13202.8, score=19.8]} {Dmel: FBgn0036926, CG7646, [Score=48.5, Expect=1e-07]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=42.7, Expect=1e-05]} {RNA1509_17148} {RNA1310_42976, RNA1509_17148} {RNA1509_17148, RNA815_19784.1}
4. MligTC455_23346 389 8.1 Mlig455_018766

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.603

Regeneration-downregulated R6: -2.996

Regeneration-depleted R6: -2.996

 1.824 - - - 0.868 - 0.956 Mlig455_018766 {REF} {Length: 921} {RNA1509_14088} {RNA1310_35033} {RNA815_47972}
5. MligTC455_47441 543 11.32 Mlig455_045866

Neo: -

Age: -

 1.778 - 0.818 - - - 0.960 Mlig455_045866 {REF} {Length: 2993} {TRANSSPLICED} {Smed: dd_Smed_v6_11834_0_1, dd_Smed_v6_11834_0_1, [RH, Score=173, Expect=4e-47]} {RNA1509_34658, RNA1509_4754} {RNA1310_5693.1, RNA1509_34658, RNA1509_4754} {RNA1509_34658, RNA1509_4754, RNA815_2001}
6. MligTC455_17580 2178 45.37 Mlig455_048028

Neo: -

Age: Down-Up-Up

 1.739 - - - 0.764 - 0.975 Mlig455_048028 {REF} {Length: 5222} {RNA1509_12558, RNA1509_43882} {RNA1310_10969, RNA1509_43882} {RNA1509_43882, RNA815_3485.1}
7. MligTC455_52007 174 3.62 Mlig455_000025

Neo: -

Age: -

 1.733 - 0.777 - - - 0.956 Mlig455_000025 {REF} {Length: 2308} {RNA1509_17229} {RNA1310_41318.2} {RNA815_54103}
8. MligTC455_45833 435 9.07 Mlig455_024105

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.498

 CHRNA3 1.709 - 0.752 - 0.957 - - Mlig455_024105 {REF} {Length: 2298} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=246.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=215.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=391, Expect=4e-131]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=378, Expect=7e-126]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=372, Expect=1e-123]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=389, Expect=2e-130]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [RH, Score=502, Expect=2e-174]} {Celegans: WBGene00006765, unc-29, Acetylcholine receptor subunit beta-type unc-29, [RH, Score=401, Expect=2e-135]} {Smed: dd_Smed_v6_12535_0_1, dd_Smed_v6_12535_0_1, [Score=465, Expect=4e-159]} {RNA1509_30259, RNA1509_56781} {RNA1310_14242, RNA1509_30259, RNA1509_56781} {RNA1509_30259, RNA1509_56781, RNA815_14328}
9. MligTC455_35129 445 9.27 Mlig455_021818

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.554

Regeneration-downregulated R2: -1.936

Regeneration-depleted R2: -1.936

 TTLL2 1.701 - 0.744 - - - 0.957 Mlig455_021818 {REF} {Length: 3696} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=228.0]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.7]; YheC/D like ATP-grasp [PF14398.8, score=20.9]} {Human: ENSG00000120440, TTLL2, tubulin tyrosine ligase like 2, [RH, Score=330, Expect=7e-103]} {Mouse: ENSMUSG00000079722, Ttll2, tubulin tyrosine ligase-like family, member 2, [RH, Score=323, Expect=4e-101]} {Dmel: FBgn0051108, CG31108, [Score=206, Expect=2e-55]} {Celegans: WBGene00008331, ttll-5, Tubulin Tyrosine Ligase Like, [Score=192, Expect=9e-52]} {Smed: dd_Smed_v6_6390_0_2, dd_Smed_v6_6390_0_2, [Score=218, Expect=2e-59]} {RNA1509_45879, RNA1509_46017, RNA1509_5384} {RNA1310_3598, RNA1509_45879, RNA1509_46017, RNA1509_5384} {RNA1509_45879, RNA1509_46017, RNA1509_5384, RNA815_5905}
10. MligTC455_32439 317 6.61 Mlig455_066022

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.840

 1.689 0.725 - - - - 0.964 Mlig455_066022 {REF} {Length: 879} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_38910} {RNA1310_50075.1} {RNA815_40697}
11. MligTC455_47637 1168 24.33 Mlig455_041729, Mlig455_042071, Mlig455_042284, Mlig455_042294

Neo: -

Age: -

 1.678 - - - 0.715 - 0.963

Mlig455_041729 {REF} {Length: 2197} {RNA1509_28165} {RNA1310_12730.1} {RNA815_5541.1}

Mlig455_042071 {REF} {Length: 2956} {RNA1509_28165} {RNA1310_12730.1} {RNA815_5541.1}

Mlig455_042284 {REF} {Length: 2962} {RNA1509_28165} {RNA1310_12730.1} {RNA815_5541.1}

Mlig455_042294 {REF} {Length: 2760} {RNA1509_28165} {RNA1310_12730.1, RNA1509_28165} {RNA1509_28165, RNA815_5541.1}
12. MligTC455_20013 777 16.18 Mlig455_002334, Mlig455_002335, Mlig455_019758

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.606/0.00058

 STOM 1.673 - 0.711 - - - 0.962

Mlig455_002334 {REF} {Length: 2498} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=113.3]} {Human: ENSG00000148175, STOM, stomatin, [Score=290, Expect=1e-95]; ENSG00000133115, STOML3, stomatin like 3, [Score=290, Expect=8e-96]} {Mouse: ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=288, Expect=6e-95]; ENSMUSG00000026880, Stom, stomatin, [Score=286, Expect=3e-94]} {Dmel: FBgn0260657, CG42540, [Score=301, Expect=9e-99]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=305, Expect=1e-100]} {Smed: dd_Smed_v6_16206_0_1, dd_Smed_v6_16206_0_1, [RH, Score=376, Expect=2e-129]} {RNA1509_30153, RNA1509_46680} {RNA1310_12353, RNA1509_30153, RNA1509_46680} {RNA1509_30153, RNA1509_46680, RNA815_4616.1}

Mlig455_002335 {REF} {Length: 1313} {NoTransDecoderORF} {RNA1509_20999} {RNA1310_66086} {RNA815_7817}

Mlig455_019758 {REF} {Length: 2302} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=113.0]} {Human: ENSG00000148175, STOM, stomatin, [Score=290, Expect=9e-96]; ENSG00000133115, STOML3, stomatin like 3, [Score=290, Expect=8e-96]} {Mouse: ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=287, Expect=7e-95]; ENSMUSG00000026880, Stom, stomatin, [Score=286, Expect=3e-94]} {Dmel: FBgn0260657, CG42540, [Score=301, Expect=9e-99]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=305, Expect=1e-100]} {Smed: dd_Smed_v6_16206_0_1, dd_Smed_v6_16206_0_1, [RH, Score=377, Expect=5e-130]} {RNA1509_30153} {RNA1310_12353} {RNA815_4616.1}
13. MligTC455_51083 1601 33.34 Mlig455_008002

Neo: -

Age: -

 SMIM7 1.664 - - - 0.709 - 0.955 Mlig455_008002 {REF} {Length: 592} {TRANSSPLICED} {Pfam: Yos1-like [PF08571.12, score=20.1]} {Human: ENSG00000214046, SMIM7, small integral membrane protein 7, [RH, Score=77.4, Expect=3e-20]; ENSG00000268790, AC008764.4, novel protein, [RH, Score=73.6, Expect=8e-19]} {Mouse: ENSMUSG00000044600, Smim7, small integral membrane protein 7, [RH, Score=79.3, Expect=4e-21]} {Celegans: WBGene00021784, cogc-4, Conserved oligomeric Golgi complex subunit 4, [RH, Score=79.7, Expect=1e-21]} {RNA1509_17989} {RNA1310_43671.1} {RNA815_20598.1}
14. MligTC455_48867 274 5.71 Mlig455_052014

Neo: -

Age: -

 CAPS2 0.977 - - - - - 0.977 Mlig455_052014 {REF} {Length: 3413} {TRANSSPLICED} {Human: ENSG00000180881, CAPS2, calcyphosine 2, [RH, Score=207, Expect=4e-60]} {Mouse: ENSMUSG00000035694, Caps2, calcyphosphine 2, [RH, Score=225, Expect=6e-65]} {Dmel: FBgn0051345, CG31345, [Score=63.5, Expect=5e-11]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [Score=70.9, Expect=7e-14]} {RNA1509_44692} {RNA1310_9646.2, RNA1509_44692} {RNA1509_44692, RNA815_2138.1}
15. MligTC455_25532 631 13.14 Mlig455_000168

Neo: -

Age: -

 0.976 - - - - - 0.976 Mlig455_000168 {REF} {Length: 1851} {TRANSSPLICED} {Pfam: Lectin C-type domain [PF00059.23, score=32.8]} {RNA1509_57829} {RNA1310_16312} {RNA815_15052}
16. MligTC455_50276 396 8.25 Mlig455_012873

Neo: -

Age: -

 FAT1 0.97 - - - - - 0.970 Mlig455_012873 {REF} {Length: 5481} {Pfam: Cadherin domain [PF00028.19, score=172.1]; EGF-like domain [PF00008.29, score=63.4]; Calcium-binding EGF domain [PF07645.17, score=28.3]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=322, Expect=3e-88]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=347, Expect=5e-96]} {Dmel: FBgn0261574, kug, kugelei, [Score=207, Expect=2e-53]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=149, Expect=2e-35]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=210, Expect=3e-54]} {RNA1509_48729} {RNA1310_5468.2} {RNA815_19574}
17. MligTC455_21640 262 5.46 Mlig455_052657

Neo: -

Age: -

 SLC6A5 0.969 - - - - - 0.969 Mlig455_052657 {REF} {Length: 4833} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=583.6]; BTB/POZ domain [PF00651.33, score=59.5]; BTB And C-terminal Kelch [PF07707.17, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=24.7]; Protein of unknown function (DUF2722) [PF10846.10, score=18.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=316, Expect=2e-92]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=315, Expect=5e-92]} {Dmel: FBgn0034911, CG5549, [Score=313, Expect=5e-89]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=228, Expect=2e-63]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=273, Expect=1e-78]} {RNA1509_27437} {RNA1310_7302.1} {RNA815_3821}
18. MligTC455_28447 1671 34.81 Mlig455_066308

Neo: -

Age: Down-Up-Down

 0.968 - - - - - 0.968 Mlig455_066308 {REF} {Length: 1281} {Pfam: Domain of unknown function (DUF4515) [PF14988.8, score=104.5]} {Mouse: ENSMUSG00000098176, Ccdc166, coiled-coil domain containing 166, [RH, Score=107, Expect=4e-26]} {Smed: dd_Smed_v6_13384_0_1, dd_Smed_v6_13384_0_1, [RH, Score=124, Expect=2e-33]} {RNA1509_33127} {RNA1310_32791.1, RNA1509_33127} {RNA1509_33127, RNA815_15652}
19. MligTC455_44972 344 7.16 Mlig455_020200

Neo: -

Age: -

 CEP72 0.968 - - - - - 0.968 Mlig455_020200 {REF} {Length: 3284} {Pfam: Leucine-rich repeat [PF14580.8, score=42.1]} {Human: ENSG00000112877, CEP72, centrosomal protein 72, [RH, Score=149, Expect=4e-37]; ENSG00000280688, CEP72, centrosomal protein 72, [RH, Score=143, Expect=3e-39]} {Mouse: ENSMUSG00000021572, Cep72, centrosomal protein 72, [RH, Score=153, Expect=1e-38]} {Smed: dd_Smed_v6_12835_0_1, dd_Smed_v6_12835_0_1, [RH, Score=174, Expect=3e-47]} {RNA1509_31408} {RNA1310_4875, RNA1509_31408} {RNA1509_31408, RNA815_15532}
20. MligTC455_15992 222 4.63 Mlig455_062899

Neo: -

Age: Up-Up-Down

 0.967 - - - - - 0.967 Mlig455_062899 {REF} {Length: 2159} {RNA1509_41203} {RNA1310_21857} {RNA815_12774}
21. MligTC455_29732 484 10.08 Mlig455_028057

Neo: -

Age: -

 XDH 0.965 - - - - - 0.965 Mlig455_028057 {REF} {Length: 4798} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=606.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=154.0]; [2Fe-2S] binding domain [PF01799.22, score=101.5]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=92.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=84.2]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=25.2]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [RH, Score=1202, Expect=0.0]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [RH, Score=1184, Expect=0.0]} {Dmel: FBgn0003308, ry, rosy, [RH, Score=1229, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [RH, Score=1093, Expect=0.0]} {RNA1509_54186, RNA1509_5759} {RNA1310_1612.1, RNA1509_54186, RNA1509_5759} {RNA1509_54186, RNA1509_5759, RNA815_3017}
22. MligTC455_43110 746 15.54 Mlig455_029622

Neo: -

Age: -

Region-enriched R2: 1.632/0.03045

 ARRDC2 0.965 - - - - - 0.965 Mlig455_029622 {REF} {Length: 1778} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=52.7]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=39.2]} {Human: ENSG00000105643, ARRDC2, arrestin domain containing 2, [Score=76.6, Expect=5e-15]} {Mouse: ENSMUSG00000110906, Arrdc2, arrestin domain containing 2, [Score=84.7, Expect=7e-18]; ENSMUSG00000002910, Arrdc2, arrestin domain containing 2, [Score=84.7, Expect=7e-18]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=76.3, Expect=2e-15]} {Celegans: WBGene00011732, arrd-17, Arrestin domain-containing protein 17, [Score=60.5, Expect=4e-10]} {Smed: dd_Smed_v6_8715_0_1, dd_Smed_v6_8715_0_1, [Score=51.6, Expect=3e-07]} {RNA1509_45476} {RNA1310_16251} {RNA815_9075}
23. MligTC455_29733 525 10.94 Mlig455_028293

Neo: -

Age: logFC(26M/2M)=1.323

 XDH 0.963 - - - - - 0.963 Mlig455_028293 {REF} {Length: 13250} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=439.5]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=543, Expect=6e-180]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=516, Expect=1e-169]} {Dmel: FBgn0003308, ry, rosy, [Score=484, Expect=6e-158]} {Celegans: WBGene00010083, xhd-1, [Score=458, Expect=7e-148]} {RNA1509_34928, RNA1509_5759} {RNA1310_1612.1, RNA1509_34928} {RNA1509_34928, RNA815_3017}
24. MligTC455_42580 98 2.04 Mlig455_014929, Mlig455_045199

Neo: -

Age: -

 NKX2-2 0.962 - - - - - 0.962

Mlig455_014929 {REF} {Length: 1652} {Pfam: Homeodomain [PF00046.31, score=70.3]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [RH, Score=138, Expect=2e-37]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [RH, Score=139, Expect=1e-37]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [RH, Score=138, Expect=4e-35]} {Celegans: WBGene00000445, ceh-22, Homeobox protein ceh-22, [RH, Score=107, Expect=6e-26]} {Smed: dd_Smed_v6_2716_0_1, dd_Smed_v6_2716_0_1, [RH, Score=120, Expect=1e-29]} {RNA1310_42496} {RNA815_52707}

Mlig455_045199 {REF} {Length: 1211} {Pfam: Homeodomain [PF00046.31, score=71.0]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [RH, Score=139, Expect=6e-39]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [RH, Score=139, Expect=3e-39]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [RH, Score=138, Expect=1e-36]} {Celegans: WBGene00000445, ceh-22, Homeobox protein ceh-22, [RH, Score=108, Expect=2e-27]} {Smed: dd_Smed_v6_2716_0_1, dd_Smed_v6_2716_0_1, [RH, Score=120, Expect=7e-31]} {RNA1310_42496} {RNA815_52707}
25. MligTC455_32691 346 7.2 Mlig455_064692

Neo: -

Age: -

 0.961 - - - - - 0.961 Mlig455_064692 {REF} {Length: 1120} {Pfam: Domain of unknown function (DUF4472) [PF14739.8, score=20.1]} {Mouse: ENSMUSG00000025272, Tro, trophinin, [Score=70.9, Expect=1e-15]} {RNA1310_132693} {RNA815_26782}
26. MligTC455_18126 1010 21.04 Mlig455_004944, Mlig455_019712

Neo: -

Age: -

Region-enriched R2: 2.788/0.00294

 BBOF1 0.96 - - - - - 0.960

Mlig455_004944 {REF} {Length: 2657} {Pfam: Domain of unknown function (DUF4515) [PF14988.8, score=61.7]} {Human: ENSG00000119636, BBOF1, basal body orientation factor 1, [Score=286, Expect=6e-90]} {Mouse: ENSMUSG00000057265, Bbof1, basal body orientation factor 1, [Score=277, Expect=3e-86]} {Dmel: FBgn0036962, CG17122, [Score=54.3, Expect=2e-07]} {Smed: dd_Smed_v6_9328_0_1, dd_Smed_v6_9328_0_1, [Score=384, Expect=6e-128]} {RNA1509_2114} {RNA1310_13083.1} {RNA815_4465}

Mlig455_019712 {REF} {Length: 3477} {Pfam: Domain of unknown function (DUF4515) [PF14988.8, score=61.5]} {Human: ENSG00000119636, BBOF1, basal body orientation factor 1, [RH, Score=335, Expect=2e-108]} {Mouse: ENSMUSG00000057265, Bbof1, basal body orientation factor 1, [RH, Score=320, Expect=7e-103]} {Dmel: FBgn0036962, CG17122, [Score=55.5, Expect=9e-08]} {Smed: dd_Smed_v6_9328_0_1, dd_Smed_v6_9328_0_1, [RH, Score=427, Expect=2e-144]} {RNA1509_2114} {RNA1310_13083.1, RNA1509_2114} {RNA1509_2114, RNA815_4465}
27. MligTC455_49650 571 11.89 Mlig455_046871

Neo: -

Age: logFC(26M/2M)=0.442

Region-enriched R2: 2.819/0.00368

 0.96 - - - - - 0.960 Mlig455_046871 {REF} {Length: 1367} {RNA1509_31002} {RNA1310_66920} {RNA815_36382}
28. MligTC455_30620 201 4.18 Mlig455_058938

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.526

 0.959 - - - 0.959 - - Mlig455_058938 {REF} {Length: 4222} {Pfam: Mab-21 protein [PF03281.16, score=39.0]} {RNA1509_51832, RNA1509_59365} {RNA1310_6164, RNA1509_59365} {RNA1509_59365, RNA815_1489.1}
29. MligTC455_38324 621 12.93 Mlig455_061532

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.278

Region-enriched R8: 2.153/0.00059

Regeneration-downregulated BL: -3.944

Regeneration-depleted BL: -3.944

 NEFH 0.959 - - - 0.959 - - Mlig455_061532 {REF} {Length: 6211} {Pfam: Tau and MAP protein, tubulin-binding repeat [PF00418.21, score=79.2]} {Human: ENSG00000100285, NEFH, neurofilament heavy, [Score=77.0, Expect=2e-13]} {Mouse: ENSMUSG00000059897, Zfp930, zinc finger protein 930, [Score=72.0, Expect=2e-12]} {Dmel: FBgn0266579, tau, [Score=85.5, Expect=1e-17]} {Celegans: WBGene00004212, ptl-1, Microtubule-associated protein, [Score=81.6, Expect=1e-15]} {Smed: dd_Smed_v6_33588_0_1, dd_Smed_v6_33588_0_1, [Score=64.3, Expect=5e-12]} {RNA1509_27273} {RNA1310_5091} {RNA815_5806}
30. MligTC455_27130 286 5.96 Mlig455_034303

Neo: -

Age: Down-Up-Down

 0.958 - - - - - 0.958 Mlig455_034303 {REF} {Length: 3045} {TRANSSPLICED} {Pfam: E3 Ubiquitin Ligase RBR C-terminal domain [PF18091.3, score=22.4]; Zn-finger in Ran binding protein and others [PF00641.20, score=18.0]} {RNA1509_8153} {RNA1310_4894.1} {RNA815_2603.1}
31. MligTC455_37811 192 3.99 Mlig455_010190, Mlig455_058688

Neo: -

Age: Down-Up-Down

 0.958 - - - - - 0.958

Mlig455_010190 {REF} {Length: 2948} {Smed: dd_Smed_v6_62611_0_1, dd_Smed_v6_62611_0_1, [RH, Score=71.6, Expect=3e-15]} {RNA1509_46223} {RNA1310_14882} {RNA815_30586}

Mlig455_058688 {REF} {Length: 3085} {Smed: dd_Smed_v6_62611_0_1, dd_Smed_v6_62611_0_1, [RH, Score=71.6, Expect=3e-15]} {RNA1509_46223} {RNA1310_14882} {RNA815_30586}
32. MligTC455_44200 2039 42.48 Mlig455_028060, Mlig455_028122

Neo: -

Age: logFC(26M/2M)=0.639

Region-enriched R4: 2.505/0.00026

Regeneration-depleted BL: -4.310
Regeneration-depleted R6: -2.510

 0.958 - - - 0.958 - -

Mlig455_028060 {REF} {Length: 1210} {RNA1509_16945, RNA1509_36375, RNA1509_37005, RNA1509_42816, RNA1509_42956, RNA1509_56773} {RNA1310_33727, RNA1509_16945, RNA1509_36375, RNA1509_37005, RNA1509_42816, RNA1509_42956, RNA1509_56773} {RNA1509_16945, RNA1509_36375, RNA1509_37005, RNA1509_42816, RNA1509_42956, RNA1509_56773, RNA815_13932}

Mlig455_028122 {REF} {Length: 1116} {RNA1509_42816} {RNA1310_33727} {RNA815_13932}
33. MligTC455_45326 203 4.22 Mlig455_048631

Neo: -

Age: -

Region-enriched R4: 5.733/0.03782
Region-enriched R5: 3.777/0.04122

 CBY1 0.958 - - - - - 0.958 Mlig455_048631 {REF} {Length: 1180} {Pfam: Chibby family [PF14645.8, score=104.8]} {Human: ENSG00000100211, CBY1, chibby family member 1, beta catenin antagonist, [RH, Score=85.5, Expect=1e-21]} {Mouse: ENSMUSG00000022428, Cby1, chibby family member 1, beta catenin antagonist, [RH, Score=96.3, Expect=2e-26]} {Smed: dd_Smed_v6_11618_0_1, dd_Smed_v6_11618_0_1, [Score=55.5, Expect=7e-11]} {RNA1509_21398} {RNA1310_29300.1} {RNA815_13488}
34. MligTC455_47442 255 5.31 Mlig455_001051

Neo: -

Age: -

 0.958 - - - - - 0.958 Mlig455_001051 {REF} {Length: 342} {TRANSSPLICED} {RNA1509_13727} {RNA1310_23632} {RNA815_13707}
35. MligTC455_35495 586 12.21 Mlig455_023069

Neo: -

Age: -

 PCF11 0.957 - - - - - 0.957 Mlig455_023069 {REF} {Length: 4117} {TRANSSPLICED} {Pfam: CID domain [PF04818.15, score=32.6]} {Human: ENSG00000165494, PCF11, PCF11, cleavage and polyadenylation factor subunit, [RH, Score=91.3, Expect=6e-18]} {Mouse: ENSMUSG00000041328, Pcf11, PCF11 cleavage and polyadenylation factor subunit, [RH, Score=92.4, Expect=2e-18]} {Dmel: FBgn0264962, Pcf11, Protein 1 of cleavage and polyadenylation factor 1, [Score=78.6, Expect=3e-14]} {Smed: dd_Smed_v6_3280_0_1, dd_Smed_v6_3280_0_1, [RH, Score=191, Expect=3e-50]} {RNA1509_13594} {RNA1310_1865.1} {RNA815_5333}
36. MligTC455_36361 38 0.78 Mlig455_031820, Mlig455_047672

Neo: -

Age: -

Region-enriched R4: 3.174/0.04287

 0.957 - - - - - 0.957

Mlig455_031820 {REF} {Length: 2062} {RNA1509_20555} {RNA1310_88884} {RNA815_46995}

Mlig455_047672 {REF} {Length: 2452} {NoTransDecoderORF} {RNA1509_10844} {RNA1310_88884} {RNA815_46995}
37. MligTC455_43338 3043 63.4 Mlig455_057398, Mlig455_059559

Neo: -

Age: logFC(26M/2M)=-0.259

Region-enriched R2: 1.086/0.00779

 CYB5D1 0.957 - - - - - 0.957

Mlig455_057398 {REF} {Length: 1138} {Pfam: Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.8]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [Score=215, Expect=1e-70]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [Score=223, Expect=7e-74]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [Score=221, Expect=3e-73]} {RNA1509_11346} {RNA1310_26198} {RNA815_11579}

Mlig455_059559 {REF} {Length: 1306} {Pfam: Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=35.0]; Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.5]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [RH, Score=260, Expect=6e-88]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [RH, Score=263, Expect=2e-89]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [RH, Score=260, Expect=3e-88]} {RNA1509_5289} {RNA1310_26198, RNA1509_5289} {RNA1509_5289, RNA815_11579}
38. MligTC455_49514 319 6.65 Mlig455_044307

Neo: -

Age: -

 AGBL2 0.957 - - - - - 0.957 Mlig455_044307 {REF} {Length: 4376} {Pfam: Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=73.3]; Zinc carboxypeptidase [PF00246.26, score=65.6]} {Human: ENSG00000285501, AGBL2, ATP/GTP binding protein like 2, [Score=560, Expect=0.0]; ENSG00000165923, AGBL2, ATP/GTP binding protein like 2, [Score=560, Expect=0.0]; ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [Score=535, Expect=7e-173]} {Mouse: ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [Score=556, Expect=0.0]; ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [Score=540, Expect=8e-174]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=538, Expect=1e-176]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=267, Expect=3e-74]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [Score=585, Expect=0.0]} {RNA1509_10895} {RNA1310_1654.2} {RNA815_1445.1}
39. MligTC455_09192 95 1.98 Mlig455_053293

Neo: -

Age: -

 0.956 - - - - - 0.956 Mlig455_053293 {REF} {Length: 767} {RNA1509_44223} {RNA1310_99471} {RNA815_46653}
40. MligTC455_23331 165 3.43 Mlig455_016108, Mlig455_036912

Neo: -

Age: -

 0.956 - - - - - 0.956

Mlig455_016108 {REF} {Length: 1041} {NoTransDecoderORF} {RNA1509_24217} {RNA1310_48796} {RNA815_25805}

Mlig455_036912 {REF} {Length: 669} {NoTransDecoderORF} {RNA1509_24217} {RNA1310_48796} {RNA815_25805}
41. MligTC455_43002 147 3.07 Mlig455_004304

Neo: -

Age: Up-Down-Down

 GLUD1 0.956 - - - - - 0.956 Mlig455_004304 {REF} {Length: 2088} {Pfam: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=134.8]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=288, Expect=8e-94]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=285, Expect=5e-93]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=288, Expect=5e-94]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=288, Expect=2e-96]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=240, Expect=4e-76]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=277, Expect=1e-90]} {RNA1509_18938, RNA1509_30743} {RNA1310_2661.2, RNA1509_18938} {RNA1509_18938, RNA815_713.2}
42. MligTC455_37586 700 14.58 Mlig455_051033

Neo: -

Age: Up-Down-Down

 MFSD10 0.955 - - - - - 0.955 Mlig455_051033 {REF} {Length: 4118} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=110.4]; MFS_1 like family [PF12832.9, score=36.5]; Sugar (and other) transporter [PF00083.26, score=31.8]} {Human: ENSG00000109736, MFSD10, major facilitator superfamily domain containing 10, [Score=52.4, Expect=1e-06]} {Mouse: ENSMUSG00000001082, Mfsd10, major facilitator superfamily domain containing 10, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00017339, F10D7.2, [Score=57.4, Expect=1e-08]} {RNA1509_36151} {RNA1310_15615} {RNA815_30478}
43. MligTC455_09133 164 3.42 Mlig455_005553

Neo: -

Age: -

 0.954 - - - - - 0.954 Mlig455_005553 {REF} {Length: 504} {RNA1509_44223} {RNA1310_54802} {RNA815_64986}
44. MligTC455_13032 67 1.39 Mlig455_030767

Neo: -

Age: -

Region-enriched R5: 3.137/0.02422

 0.954 - - - - - 0.954 Mlig455_030767 {REF} {Length: 681} {NoTransDecoderORF} {RNA1509_36012} {RNA1310_55986} {RNA815_20629}
45. MligTC455_15445 1402 29.22 Mlig455_045380

Neo: -

Age: logFC(26M/2M)=-0.318

 C20orf96 0.954 - - - - - 0.954 Mlig455_045380 {REF} {Length: 1425} {Pfam: Domain of unknown function (DUF4618) [PF15397.8, score=141.8]} {Human: ENSG00000196476, C20orf96, chromosome 20 open reading frame 96, [RH, Score=57.0, Expect=1e-08]} {Mouse: ENSMUSG00000032680, 6820408C15Rik, RIKEN cDNA 6820408C15 gene, [Score=47.8, Expect=9e-06]} {RNA1509_21367} {RNA1310_14669, RNA1509_21367} {RNA1509_21367, RNA815_11985.1}
46. MligTC455_22804 350 7.3 Mlig455_067193

Neo: -

Age: logFC(26M/2M)=-0.439

Region-enriched R2: 2.883/0.00412

 TEKT3 0.954 - - - - - 0.954 Mlig455_067193 {REF} {Length: 4067} {Pfam: Tektin family [PF03148.16, score=437.3]; fzo-like conserved region [PF04799.15, score=18.2]} {Human: ENSG00000125409, TEKT3, tektin 3, [Score=358, Expect=6e-119]} {Mouse: ENSMUSG00000042189, Tekt3, tektin 3, [Score=342, Expect=6e-113]} {Dmel: FBgn0052820, CG32820, [Score=286, Expect=5e-91]} {Smed: dd_Smed_v6_6511_0_1, dd_Smed_v6_6511_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_7137} {RNA1310_13532} {RNA815_5924}
47. MligTC455_35886 941 19.59 Mlig455_013877

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

Region-specific R4: 1.689

Region-enriched R4: 1.129/0.00623

Regeneration-downregulated R4: -1.365

Regeneration-depleted R4: -1.365

 HRASLS2 0.954 - - - 0.954 - - Mlig455_013877 {REF} {Length: 1953} {Pfam: Lecithin retinol acyltransferase [PF04970.15, score=65.8]} {Human: ENSG00000133328, HRASLS2, HRAS like suppressor 2, [Score=52.4, Expect=7e-08]} {Mouse: ENSMUSG00000028003, Lrat, lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase), [RH, Score=50.4, Expect=5e-07]} {RNA1509_5071, RNA1509_56927} {RNA1310_21690, RNA1509_56927} {RNA1509_56927, RNA815_8872}
48. MligTC455_38195 432 9.01 Mlig455_063704

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.492

 TRPM1 0.954 - - - - - 0.954 Mlig455_063704 {REF} {Length: 5184} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=94.9]; Ankyrin repeats (many copies) [PF13637.8, score=83.0]; Ankyrin repeats (many copies) [PF13857.8, score=63.8]; Ankyrin repeat [PF13606.8, score=61.6]; Ankyrin repeat [PF00023.32, score=55.8]; Ion transport protein [PF00520.33, score=53.8]} {Human: ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=132, Expect=2e-30]; ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=132, Expect=2e-30]; ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=129, Expect=1e-29]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=131, Expect=3e-30]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=129, Expect=9e-30]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=118, Expect=2e-26]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=79.0, Expect=2e-14]} {Smed: dd_Smed_v6_10717_0_1, dd_Smed_v6_10717_0_1, [RH, Score=189, Expect=2e-49]} {RNA1509_33075, RNA1509_41062, RNA1509_48059, RNA1509_9269} {RNA1310_4916, RNA1509_33075, RNA1509_41062, RNA1509_48059, RNA1509_9269} {RNA1509_33075, RNA1509_41062, RNA1509_48059, RNA1509_9269, RNA815_3093}
49. MligTC455_40038 463 9.64 Mlig455_044413

Neo: -

Age: Down-Up-Up

 0.954 - - - - - 0.954 Mlig455_044413 {REF} {Length: 1167} {Pfam: Fruit fly transformer protein [PF06495.13, score=22.2]; Ets-domain [PF00178.24, score=22.0]; Coronavirus nucleocapsid [PF00937.20, score=18.0]} {RNA1509_38421, RNA1509_58641} {RNA1310_33082, RNA1509_38421, RNA1509_58641} {RNA1509_38421, RNA1509_58641, RNA815_26283}
50. MligTC455_40721 26 0.54 Mlig455_028262

Neo: -

Age: Down-Down-Down

 CHAF1A 0.954 - - - - - 0.954 Mlig455_028262 {REF} {Length: 324} {TRANSSPLICED} {Pfam: Chromatin assembly factor 1 subunit A [PF12253.10, score=88.9]} {Human: ENSG00000167670, CHAF1A, chromatin assembly factor 1 subunit A, [RH, Score=100, Expect=7e-22]} {Mouse: ENSMUSG00000002835, Chaf1a, chromatin assembly factor 1, subunit A (p150), [RH, Score=86.7, Expect=2e-17]} {Dmel: FBgn0030054, Caf1-180, Chromatin assembly factor 1, p180 subunit, [RH, Score=113, Expect=3e-26]} {Celegans: WBGene00011532, chaf-1, CHromatin Assembly Factor, [Score=62.4, Expect=3e-10]} {Smed: dd_Smed_v6_8919_0_1, dd_Smed_v6_8919_0_1, [RH, Score=99.8, Expect=3e-22]} {RNA1509_45107} {RNA1310_100948} {RNA815_65244}
51. MligTC455_08310 465 9.68 Mlig455_027082

Neo: -

Age: -

Region-enriched R2: 1.747/0.03234

 0.953 - - - - - 0.953 Mlig455_027082 {REF} {Length: 2992} {TRANSSPLICED} {RNA1509_26760, RNA1509_28914, RNA1509_42937} {RNA1310_5574.1, RNA1509_26760, RNA1509_28914, RNA1509_42937} {RNA1509_26760, RNA1509_28914, RNA1509_42937, RNA815_9311}
52. MligTC455_36867 593 12.35 Mlig455_003271, Mlig455_014183, Mlig455_035891, Mlig455_035892, Mlig455_046980

Neo: Germline

Age: -

 0.953 - - - - - 0.953

Mlig455_003271 {REF} {Length: 2634} {Pfam: Myb/SANT-like DNA-binding domain [PF13837.8, score=34.6]} {RNA1509_9680} {RNA1310_22937, RNA1509_9680} {RNA1509_9680, RNA815_12122}

Mlig455_014183 {REF} {Length: 2608} {Pfam: Myb/SANT-like DNA-binding domain [PF13837.8, score=34.6]} {RNA1509_9680} {RNA1310_22937} {RNA815_12122}

Mlig455_035891 {REF} {Length: 950} {Pfam: Myb/SANT-like DNA-binding domain [PF13837.8, score=34.6]} {RNA1509_9680} {RNA1310_22937} {RNA815_12122}

Mlig455_035892 {REF} {Length: 332} {NoTransDecoderORF} {RNA1509_9680} {RNA1310_68465}

Mlig455_046980 {REF} {Length: 6307} {Pfam: Myb/SANT-like DNA-binding domain [PF13837.8, score=34.6]} {RNA1509_9680} {RNA1310_22937} {RNA815_12122}
53. MligTC455_42485 159 3.31 Mlig455_046457

Neo: -

Age: -

 0.953 - - - - - 0.953 Mlig455_046457 {REF} {Length: 846} {RNA1310_40237.1} {RNA815_18246}
54. MligTC455_29967 39 0.81 Mlig455_047063, Mlig455_061991

Neo: -

Age: logFC(26M/2M)=-0.424

 DDX58 0.952 - - - - - 0.952

Mlig455_047063 {REF} {Length: 1487} {Pfam: Integrase zinc binding domain [PF17921.3, score=64.5]; H2C2 zinc finger [PF09337.12, score=23.2]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=58.5, Expect=4e-09]} {RNA1509_56078} {RNA1310_617} {RNA815_3663}

Mlig455_061991 {REF} {Length: 5119} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=110.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=102.1]; Type III restriction enzyme, res subunit [PF04851.17, score=69.6]; Integrase zinc binding domain [PF17921.3, score=64.0]; Integrase core domain [PF00665.28, score=54.6]; DEAD/DEAH box helicase [PF00270.31, score=50.0]; Helicase conserved C-terminal domain [PF00271.33, score=47.6]; SWI2/SNF2 ATPase [PF18766.3, score=30.1]; H2C2 zinc finger [PF09337.12, score=20.1]; Integrase core domain [PF13683.8, score=18.5]} {Human: ENSG00000107201, DDX58, DExD/H-box helicase 58, [Score=168, Expect=1e-41]} {Mouse: ENSMUSG00000040296, Ddx58, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, [Score=154, Expect=5e-38]; ENSMUSG00000017830, Dhx58, DEXH (Asp-Glu-X-His) box polypeptide 58, [Score=147, Expect=8e-36]} {Dmel: FBgn0039016, Dcr-1, Dicer-1, [Score=50.8, Expect=1e-05]} {Celegans: WBGene00001090, drh-1, Dicer Related Helicase; Dicer-related helicase, [Score=112, Expect=6e-25]} {Smed: dd_Smed_v6_3742_0_1, dd_Smed_v6_3742_0_1, [Score=218, Expect=1e-57]} {RNA1509_41041, RNA1509_9178} {RNA1310_2530.1, RNA1509_41041} {RNA1509_41041, RNA815_790.1}
55. MligTC455_34007 638 13.3 Mlig455_042214, Mlig455_065850

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.257

 0.952 - - - - - 0.952

Mlig455_042214 {REF} {Length: 4852} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=134.1]; Ankyrin repeats (many copies) [PF13637.8, score=108.4]; Ankyrin repeats (many copies) [PF13857.8, score=71.2]; Ankyrin repeat [PF13606.8, score=64.0]; Ankyrin repeat [PF00023.32, score=32.9]; Family of unknown function (DUF6189) [PF19688.1, score=31.1]; 3,4-dihydroxy-2-butanone 4-phosphate synthase [PF00926.21, score=30.1]; Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus [PF04813.14, score=21.5]} {RNA1509_39348} {RNA1310_21309.1} {RNA815_17914}

Mlig455_065850 {REF} {Length: 4926} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=143.2]; Ankyrin repeats (many copies) [PF13637.8, score=112.8]; Ankyrin repeats (many copies) [PF13857.8, score=67.4]; Ankyrin repeat [PF13606.8, score=61.4]; Family of unknown function (DUF6189) [PF19688.1, score=30.5]; Ankyrin repeat [PF00023.32, score=30.0]; 3,4-dihydroxy-2-butanone 4-phosphate synthase [PF00926.21, score=26.2]} {RNA1509_39348} {RNA1310_21309.1} {RNA815_26798.1}
56. MligTC455_35987 923 19.24 Mlig455_031417

Neo: -

Age: Down-Up-Down

 MAP4K5 0.952 - - - - - 0.952 Mlig455_031417 {REF} {Length: 4927} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=198.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=129.5]; CNH domain [PF00780.24, score=116.1]; ABC1 atypical kinase-like domain [PF03109.18, score=28.6]} {Human: ENSG00000012983, MAP4K5, mitogen-activated protein kinase kinase kinase kinase 5, [RH, Score=352, Expect=3e-107]; ENSG00000011566, MAP4K3, mitogen-activated protein kinase kinase kinase kinase 3, [RH, Score=346, Expect=1e-104]} {Mouse: ENSMUSG00000024948, Map4k2, mitogen-activated protein kinase kinase kinase kinase 2, [RH, Score=492, Expect=9e-161]; ENSMUSG00000106850, Map4k2, mitogen-activated protein kinase kinase kinase kinase 2, [RH, Score=492, Expect=9e-161]} {Dmel: FBgn0263395, hppy, happyhour, [RH, Score=329, Expect=3e-96]} {Celegans: WBGene00022603, gck-2, Mitogen-activated protein kinase kinase kinase kinase, [RH, Score=322, Expect=2e-96]} {Smed: dd_Smed_v6_5913_0_1, dd_Smed_v6_5913_0_1, [RH, Score=568, Expect=0.0]} {RNA1509_11811} {RNA1310_2202.1, RNA1509_11811} {RNA1509_11811, RNA815_1529}
57. MligTC455_36187 339 7.06 Mlig455_036148

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.329

 KCNH7 0.952 - - - - - 0.952 Mlig455_036148 {REF} {Length: 4967} {Pfam: Ion transport protein [PF00520.33, score=125.0]; Cyclic nucleotide-binding domain [PF00027.31, score=50.6]; PAS domain [PF13426.9, score=47.2]; Ion channel [PF07885.18, score=46.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=25.4]; PAS fold [PF00989.27, score=24.3]; PAS fold [PF08447.14, score=24.1]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [RH, Score=851, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [RH, Score=824, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [RH, Score=821, Expect=0.0]} {Mouse: ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [RH, Score=960, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [RH, Score=772, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [RH, Score=759, Expect=0.0]} {Smed: dd_Smed_v6_12621_0_1, dd_Smed_v6_12621_0_1, [RH, Score=878, Expect=0.0]} {RNA1509_16542} {RNA1310_9991} {RNA815_4089.1}
58. MligTC455_36910 84 1.75 Mlig455_031683

Neo: -

Age: -

 0.952 - - - - - 0.952 Mlig455_031683 {REF} {Length: 4716} {RNA1509_36080} {RNA1310_44068, RNA1509_36080} {RNA1509_36080, RNA815_39601}
59. MligTC455_44047 834 17.37 Mlig455_013992

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.621

 SLC6A2 0.952 - - - - - 0.952 Mlig455_013992 {REF} {Length: 3099} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=718.1]} {Human: ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [RH, Score=632, Expect=0.0]; ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [RH, Score=611, Expect=0.0]; ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [RH, Score=611, Expect=0.0]} {Mouse: ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [RH, Score=629, Expect=0.0]; ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [RH, Score=620, Expect=0.0]; ENSMUSG00000020838, Slc6a4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, [RH, Score=598, Expect=0.0]} {Dmel: FBgn0034136, DAT, Dopamine transporter, [RH, Score=728, Expect=0.0]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [RH, Score=620, Expect=0.0]} {Smed: dd_Smed_v6_17986_0_1, dd_Smed_v6_17986_0_1, [RH, Score=771, Expect=0.0]} {RNA1509_10666} {RNA1310_15942} {RNA815_3113}
60. MligTC455_11148 110 2.29 Mlig455_015359

Neo: -

Age: -

 C11orf65 0.951 - - - - - 0.951 Mlig455_015359 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: BNIP3 [PF06553.14, score=27.4]; Restriction endonuclease FokI, recognition domain [PF02981.17, score=20.9]; IQ calmodulin-binding motif [PF00612.29, score=19.1]} {Human: ENSG00000166323, C11orf65, chromosome 11 open reading frame 65, [RH, Score=224, Expect=1e-67]} {Mouse: ENSMUSG00000005131, 4930550C14Rik, RIKEN cDNA 4930550C14 gene, [RH, Score=210, Expect=3e-62]} {Smed: dd_Smed_v6_13591_0_1, dd_Smed_v6_13591_0_1, [RH, Score=236, Expect=2e-72]} {RNA1310_22540.2} {RNA815_13464}
61. MligTC455_31846 149 3.11 Mlig455_068643

Neo: -

Age: -

 LRRC7 0.951 - - - - - 0.951 Mlig455_068643 {REF} {Length: 4432} {TRANSSPLICED} {Pfam: Leucine rich repeat [PF13855.8, score=123.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=68.5]; PDZ domain [PF00595.26, score=46.1]; PDZ domain [PF17820.3, score=22.3]} {Human: ENSG00000033122, LRRC7, leucine rich repeat containing 7, [RH, Score=356, Expect=2e-102]} {Mouse: ENSMUSG00000028176, Lrrc7, leucine rich repeat containing 7, [RH, Score=362, Expect=3e-105]} {Dmel: FBgn0033984, Lap1, [RH, Score=295, Expect=6e-85]} {Celegans: WBGene00002632, let-413, [Score=296, Expect=5e-87]} {Smed: dd_Smed_v6_4770_0_1, dd_Smed_v6_4770_0_1, [RH, Score=317, Expect=1e-91]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}
62. MligTC455_33876 123 2.56 Mlig455_030510

Neo: -

Age: -

 0.951 - - - - - 0.951 Mlig455_030510 {REF} {Length: 1004} {RNA1509_42280} {RNA1310_51836} {RNA815_8810.1}
63. MligTC455_21975 1445 30.1 Mlig455_067235

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.598

Region-specific R2: 3.235

Region-enriched R2: 3.090/0.00000

 BMPER 0.95 - - - - - 0.950 Mlig455_067235 {REF} {Length: 21751} {Pfam: von Willebrand factor type D domain [PF00094.27, score=57.1]; C8 domain [PF08742.13, score=24.9]; Neurensin [PF14927.8, score=24.8]} {Human: ENSG00000164619, BMPER, BMP binding endothelial regulator, [Score=80.9, Expect=4e-14]; ENSG00000135253, KCP, kielin/chordin-like protein, [Score=78.6, Expect=4e-13]; ENSG00000275395, FCGBP, Fc fragment of IgG binding protein, [Score=78.6, Expect=5e-13]} {Mouse: ENSMUSG00000031963, Bmper, BMP-binding endothelial regulator, [Score=78.6, Expect=2e-13]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=226, Expect=6e-58]} {Smed: dd_Smed_v6_194_0_1, dd_Smed_v6_194_0_1, [Score=244, Expect=8e-64]} {RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_31, RNA1509_5282} {RNA1310_7.1, RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_5282} {RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_5282, RNA815_4}
64. MligTC455_46887 1771 36.89 Mlig455_023150

Neo: -

Age: logFC(26M/2M)=-0.580

 SLC25A14 0.95 - - - - - 0.950 Mlig455_023150 {REF} {Length: 2121} {Pfam: Mitochondrial carrier protein [PF00153.29, score=221.0]} {Human: ENSG00000102078, SLC25A14, solute carrier family 25 member 14, [RH, Score=287, Expect=1e-95]; ENSG00000174032, SLC25A30, solute carrier family 25 member 30, [RH, Score=281, Expect=2e-93]} {Mouse: ENSMUSG00000031105, Slc25a14, solute carrier family 25 (mitochondrial carrier, brain), member 14, [RH, Score=284, Expect=2e-94]; ENSMUSG00000022003, Slc25a30, solute carrier family 25, member 30, [RH, Score=281, Expect=9e-94]} {Dmel: FBgn0036199, Bmcp, [RH, Score=259, Expect=8e-85]} {Celegans: WBGene00015186, misc-1, MItochondrial Solute Carrier, [Score=166, Expect=1e-48]} {Smed: dd_Smed_v6_8945_0_8, dd_Smed_v6_8945_0_8, [RH, Score=250, Expect=1e-81]} {RNA1509_12259} {RNA1310_31014} {RNA815_1562.1}
65. MligTC455_47024 1789 37.28 Mlig455_009460, Mlig455_009471

Neo: -

Age: Down-Up-Up

 DYNLL1 0.95 - - - - - 0.950

Mlig455_009460 {REF} {Length: 1726} {Pfam: Dynein light chain type 1 [PF01221.20, score=54.4]; EF hand [PF00036.34, score=34.3]; EF-hand domain pair [PF13499.8, score=31.0]; EF-hand domain [PF13405.8, score=22.7]; EF-hand domain pair [PF13833.8, score=19.6]} {Mouse: ENSMUSG00000064063, BC048507, cDNA sequence BC048507, [Score=49.7, Expect=3e-08]} {Dmel: FBgn0011760, ctp, cut up, [Score=42.7, Expect=8e-06]} {Smed: dd_Smed_v6_6707_0_3, dd_Smed_v6_6707_0_3, [Score=127, Expect=7e-38]} {RNA1509_13767, RNA1509_23606, RNA1509_58985} {RNA1310_16660, RNA1509_13767, RNA1509_23606, RNA1509_58985} {RNA1509_13767, RNA1509_23606, RNA1509_58985, RNA815_6771}

Mlig455_009471 {REF} {Length: 995} {Pfam: Dynein light chain type 1 [PF01221.20, score=57.5]; EF hand [PF00036.34, score=34.3]; EF-hand domain pair [PF13499.8, score=31.0]; EF-hand domain [PF13405.8, score=22.7]; EF-hand domain pair [PF13833.8, score=19.6]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=43.1, Expect=1e-05]} {Mouse: ENSMUSG00000064063, BC048507, cDNA sequence BC048507, [Score=51.6, Expect=7e-09]} {Dmel: FBgn0011760, ctp, cut up, [Score=44.7, Expect=2e-06]} {Celegans: WBGene00001005, dlc-1, Dynein light chain 1, cytoplasmic, [Score=42.4, Expect=1e-05]} {Smed: dd_Smed_v6_6707_0_3, dd_Smed_v6_6707_0_3, [Score=129, Expect=2e-38]} {RNA1509_23606} {RNA1310_16660} {RNA815_6771}
66. MligTC455_53512 916 19.08 Mlig455_028726

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.315

Region-enriched R2: 1.504/0.01018

 IFT172 0.95 - - - - - 0.950 Mlig455_028726 {REF} {Length: 2813} {Pfam: Region in Clathrin and VPS [PF00637.22, score=23.3]; Tetratricopeptide repeat [PF13176.8, score=19.3]} {Human: ENSG00000138002, IFT172, intraflagellar transport 172, [Score=871, Expect=0.0]} {Mouse: ENSMUSG00000038564, Ift172, intraflagellar transport 172, [Score=873, Expect=0.0]} {Dmel: FBgn0035317, Oseg2, Outer segment 2, [Score=546, Expect=5e-173]} {Celegans: WBGene00003883, osm-1, Intraflagellar transport protein osm-1, [Score=517, Expect=2e-162]} {Smed: dd_Smed_v6_10638_0_1, dd_Smed_v6_10638_0_1, [Score=615, Expect=0.0]} {RNA1509_2378} {RNA1310_994} {RNA815_250}

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