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Results for MligTC455_36233

Cluster	Total UMI counts	Global CPM	Transcripts	Categories	Human homolog	Annotation
MligTC455_36233	477	9.93	Mlig455_034713, Mlig455_067592	Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.950	HCK	Mlig455_034713 {REF} {Length: 2484} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=286.1]; Protein kinase domain [PF00069.27, score=164.1]; SH2 domain [PF00017.26, score=31.9]; Variant SH3 domain [PF14604.8, score=26.6]; Haspin like kinase domain [PF12330.10, score=26.5]; ABC1 atypical kinase-like domain [PF03109.18, score=23.6]; SH3 domain [PF00018.30, score=20.1]} {Human: ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=2e-111]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=333, Expect=5e-109]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=333, Expect=3e-108]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=330, Expect=3e-107]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=336, Expect=6e-110]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=333, Expect=2e-108]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=332, Expect=3e-108]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=330, Expect=1e-107]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=325, Expect=3e-106]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=308, Expect=2e-99]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=333, Expect=1e-109]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=378, Expect=1e-126]} {RNA1509_12794} {RNA1310_15672} {RNA815_6298} Mlig455_067592 {REF} {Length: 2530} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.9]; Protein kinase domain [PF00069.27, score=163.9]; Variant SH3 domain [PF14604.8, score=40.0]; SH3 domain [PF00018.30, score=39.0]; SH2 domain [PF00017.26, score=31.8]; Haspin like kinase domain [PF12330.10, score=26.4]; ABC1 atypical kinase-like domain [PF03109.18, score=23.5]; Variant SH3 domain [PF07653.19, score=18.9]} {Human: ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=352, Expect=5e-116]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=7e-111]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=3e-111]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=338, Expect=6e-110]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=343, Expect=3e-112]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=340, Expect=6e-111]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=340, Expect=6e-111]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=335, Expect=2e-109]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=334, Expect=4e-109]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=318, Expect=1e-102]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=337, Expect=8e-111]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=384, Expect=1e-128]} {RNA1509_12794} {RNA1310_15672, RNA1509_12794} {RNA1509_12794, RNA815_6298}

Cluster

Total UMI counts

Global CPM

Transcripts

Categories

Human homolog

Annotation

MligTC455_36233

477

9.93

Mlig455_034713, Mlig455_067592

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.950

HCK

Mlig455_034713 {REF} {Length: 2484} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=286.1]; Protein kinase domain [PF00069.27, score=164.1]; SH2 domain [PF00017.26, score=31.9]; Variant SH3 domain [PF14604.8, score=26.6]; Haspin like kinase domain [PF12330.10, score=26.5]; ABC1 atypical kinase-like domain [PF03109.18, score=23.6]; SH3 domain [PF00018.30, score=20.1]} {Human: ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=2e-111]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=333, Expect=5e-109]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=333, Expect=3e-108]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=330, Expect=3e-107]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=336, Expect=6e-110]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=333, Expect=2e-108]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=332, Expect=3e-108]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=330, Expect=1e-107]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=325, Expect=3e-106]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=308, Expect=2e-99]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=333, Expect=1e-109]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=378, Expect=1e-126]} {RNA1509_12794} {RNA1310_15672} {RNA815_6298}

Mlig455_067592 {REF} {Length: 2530} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.9]; Protein kinase domain [PF00069.27, score=163.9]; Variant SH3 domain [PF14604.8, score=40.0]; SH3 domain [PF00018.30, score=39.0]; SH2 domain [PF00017.26, score=31.8]; Haspin like kinase domain [PF12330.10, score=26.4]; ABC1 atypical kinase-like domain [PF03109.18, score=23.5]; Variant SH3 domain [PF07653.19, score=18.9]} {Human: ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=352, Expect=5e-116]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=7e-111]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=3e-111]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=338, Expect=6e-110]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=343, Expect=3e-112]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=340, Expect=6e-111]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=340, Expect=6e-111]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=335, Expect=2e-109]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=334, Expect=4e-109]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=318, Expect=1e-102]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=337, Expect=8e-111]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=384, Expect=1e-128]} {RNA1509_12794} {RNA1310_15672, RNA1509_12794} {RNA1509_12794, RNA815_6298}

Cumulative graph for MligTC455_36233

Region-enriched expression

Region	logFC	logCPM	Pvalue	FDR
RegionR1	-1.716	3.59	0.28824	0.94067
RegionR2	0.175	3.59	0.78262	1.00000
RegionR3	0.429	3.59	0.43436	0.95230
RegionR4	-0.424	3.59	0.52488	0.84923
RegionR5	-1.041	3.59	0.07805	0.25743
RegionR6	0.49	3.59	0.36357	0.94548
RegionR7	1.036	3.59	0.06470	0.48874
RegionR8	1.05	3.59	0.10940	0.61522

Regeneration-enriched expression

Region	logFC	logCPM	PValue	FDR
RegenerationR1	-4.937	3.59	0.40037	1.00000
RegenerationR2	-0.315	3.59	0.59475	0.91319
RegenerationR3	-0.136	3.59	0.82581	0.98974
RegenerationR4	0.588	3.59	0.37469	0.79744
RegenerationR5	0.273	3.59	0.67301	0.94214
RegenerationR6	0.184	3.59	0.75998	0.95683
RegenerationBL	-1.407	3.59	0.05144	0.26125
RegenerationTP	-0.728	3.59	0.28810	0.73383

Genes with expression patterns similar to MligTC455_36233

Nr.	Cluster	Total UMI counts	Global CPM	Transcripts	Categories	Human homolog	Σ Spearman correlations	Int1	Int2	Int3	Reg1	Reg2	Reg3	Annotation
1.	MligTC455_36233	477	9.93	Mlig455_034713, Mlig455_067592	Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.950	HCK	6	1.000	1.000	1.000	1.000	1.000	1.000	Mlig455_034713 {REF} {Length: 2484} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=286.1]; Protein kinase domain [PF00069.27, score=164.1]; SH2 domain [PF00017.26, score=31.9]; Variant SH3 domain [PF14604.8, score=26.6]; Haspin like kinase domain [PF12330.10, score=26.5]; ABC1 atypical kinase-like domain [PF03109.18, score=23.6]; SH3 domain [PF00018.30, score=20.1]} {Human: ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=2e-111]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=333, Expect=5e-109]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=333, Expect=3e-108]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=330, Expect=3e-107]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=336, Expect=6e-110]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=333, Expect=2e-108]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=332, Expect=3e-108]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=330, Expect=1e-107]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=325, Expect=3e-106]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=308, Expect=2e-99]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=333, Expect=1e-109]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=378, Expect=1e-126]} {RNA1509_12794} {RNA1310_15672} {RNA815_6298} Mlig455_067592 {REF} {Length: 2530} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.9]; Protein kinase domain [PF00069.27, score=163.9]; Variant SH3 domain [PF14604.8, score=40.0]; SH3 domain [PF00018.30, score=39.0]; SH2 domain [PF00017.26, score=31.8]; Haspin like kinase domain [PF12330.10, score=26.4]; ABC1 atypical kinase-like domain [PF03109.18, score=23.5]; Variant SH3 domain [PF07653.19, score=18.9]} {Human: ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=352, Expect=5e-116]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=7e-111]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=340, Expect=3e-111]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=338, Expect=6e-110]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=343, Expect=3e-112]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=340, Expect=6e-111]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=340, Expect=6e-111]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=335, Expect=2e-109]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=334, Expect=4e-109]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=318, Expect=1e-102]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=337, Expect=8e-111]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=384, Expect=1e-128]} {RNA1509_12794} {RNA1310_15672, RNA1509_12794} {RNA1509_12794, RNA815_6298}
2.	MligTC455_32205	53	1.1	Mlig455_012745, Mlig455_057811, Mlig455_057842	Neo: - Age: Up-Down-Down	MACF1, PLEC	1.739	-	-	-	0.783	0.956	-	Mlig455_012745 {REF} {Length: 527} {Pfam: Calponin homology (CH) domain [PF00307.33, score=61.6]} {Human: ENSG00000127603, MACF1, microtubule-actin crosslinking factor 1, [Score=108, Expect=2e-27]; ENSG00000160460, SPTBN4, spectrin beta, non-erythrocytic 4, [Score=108, Expect=1e-27]; ENSG00000178209, PLEC, plectin, [Score=107, Expect=4e-27]} {Mouse: ENSMUSG00000011751, Sptbn4, spectrin beta, non-erythrocytic 4, [Score=109, Expect=6e-28]; ENSMUSG00000028649, Macf1, microtubule-actin crosslinking factor 1, [Score=108, Expect=1e-27]; ENSMUSG00000022565, Plec, plectin, [Score=106, Expect=5e-27]} {Dmel: FBgn0013733, shot, short stop, [Score=100, Expect=5e-25]} {Celegans: WBGene00004855, sma-1, Beta chain spectrin homolog Sma1; SMAll, [Score=94.7, Expect=3e-23]} {Smed: dd_Smed_v6_1205_0_5, dd_Smed_v6_1205_0_5, [Score=107, Expect=1e-27]} {RNA1509_10105} {RNA1310_15734} {RNA815_17574.1} Mlig455_057811 {REF} {Length: 26554} {Pfam: Plectin repeat [PF00681.22, score=73.1]; Spectrin repeat [PF00435.23, score=20.8]} {Human: ENSG00000127603, MACF1, microtubule-actin crosslinking factor 1, [Score=117, Expect=1e-24]; ENSG00000151914, DST, dystonin, [Score=114, Expect=9e-24]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [Score=126, Expect=1e-27]} {Dmel: FBgn0013733, shot, short stop, [Score=223, Expect=4e-57]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=53.5, Expect=9e-06]} {Smed: dd_Smed_v6_1205_0_5, dd_Smed_v6_1205_0_5, [Score=304, Expect=2e-81]} {RNA1509_9103} {RNA1310_33.1} {RNA815_126} Mlig455_057842 {REF} {Length: 7846} {Pfam: Spectrin repeat [PF00435.23, score=46.8]; Plectin repeat [PF00681.22, score=35.6]} {Human: ENSG00000178209, PLEC, plectin, [Score=216, Expect=2e-55]} {Mouse: ENSMUSG00000022565, Plec, plectin, [Score=207, Expect=6e-53]} {Dmel: FBgn0013733, shot, short stop, [Score=314, Expect=2e-85]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=206, Expect=7e-53]} {Smed: dd_Smed_v6_1205_0_15, dd_Smed_v6_1205_0_15, [Score=189, Expect=9e-48]} {RNA1509_10105} {RNA1310_605.1} {RNA815_126}
3.	MligTC455_13322	348	7.26	Mlig455_045509	Neo: - Age: Up-Down-Up		1.662	-	-	-	-	0.950	0.712	Mlig455_045509 {REF} {Length: 2060} {RNA1509_43769} {RNA1310_13950} {RNA815_5909}
4.	MligTC455_40821	347	7.22	Mlig455_016792	Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.666		0.989	-	-	-	0.989	-	-	Mlig455_016792 {REF} {Length: 1267} {TRANSSPLICED} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=48.2]; short chain dehydrogenase [PF00106.27, score=38.4]} {Dmel: FBgn0030968, CG7322, [Score=52.4, Expect=3e-08]} {Celegans: WBGene00000984, dhs-21, L-xylulose reductase, [Score=51.6, Expect=4e-08]} {RNA1509_44109} {RNA1310_24446.1} {RNA815_13838}
5.	MligTC455_35438	118	2.46	Mlig455_049789	Neo: - Age: -	QDPR	0.97	-	-	-	0.970	-	-	Mlig455_049789 {REF} {Length: 2364} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=60.2]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=35.7]; short chain dehydrogenase [PF00106.27, score=33.3]; NAD dependent epimerase/dehydratase family [PF01370.23, score=20.4]} {Human: ENSG00000151552, QDPR, quinoid dihydropteridine reductase, [Score=246, Expect=6e-77]} {Mouse: ENSMUSG00000015806, Qdpr, quinoid dihydropteridine reductase, [Score=248, Expect=8e-78]} {Dmel: FBgn0035964, Dhpr, Dihydropteridine reductase, [RH, Score=226, Expect=1e-69]} {Celegans: WBGene00011398, qdpr-1, Quinoid DihydroPteridine Reductase, [Score=226, Expect=8e-70]} {Smed: dd_Smed_v6_2408_0_1, dd_Smed_v6_2408_0_1, [RH, Score=203, Expect=2e-61]} {RNA1509_19705, RNA1509_48132} {RNA1310_19924, RNA1509_19705, RNA1509_48132} {RNA1509_19705, RNA1509_48132, RNA815_8952}
6.	MligTC455_53012	894	18.63	Mlig455_029158, Mlig455_041436	Neo: - Age: Down-Up-Down		0.956	-	-	-	-	0.956	-	Mlig455_029158 {REF} {Length: 848} {TRANSSPLICED} {RNA1509_24093} {RNA1310_59695} {RNA815_13022.1} Mlig455_041436 {REF} {Length: 1146} {TRANSSPLICED} {RNA1509_24093, RNA1509_34847} {RNA1310_59695, RNA1509_34847} {RNA1509_34847, RNA815_13022.1}