Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_36802 | 2078 | 43.30 | Mlig455_010812 | Neo: - |
FAT1 | Mlig455_010812 {REF} {Length: 8313} {Pfam: Cadherin domain [PF00028.19, score=230.6]; Laminin G domain [PF02210.26, score=95.2]; Cadherin cytoplasmic region [PF01049.19, score=78.0]; Laminin G domain [PF00054.25, score=62.2]; Cadherin-like [PF16184.7, score=29.4]; Bacterial cadherin-like domain [PF17803.3, score=20.3]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=200, Expect=2e-50]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=182, Expect=5e-45]; ENSMUSG00000016028, Celsr1, cadherin, EGF LAG seven-pass G-type receptor 1, [Score=180, Expect=1e-44]; ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=176, Expect=3e-43]} {Dmel: FBgn0015609, CadN, Cadherin-N, [Score=203, Expect=9e-52]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=159, Expect=1e-38]} {Smed: dd_Smed_v6_14778_0_1, dd_Smed_v6_14778_0_1, [Score=109, Expect=1e-23]} {RNA1509_321} {RNA1310_106.1} {RNA815_46.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.394 | 5.6 | 0.59508 | 1.00000 | |
RegionR2 | 0.602 | 5.6 | 0.14288 | 0.47052 | |
RegionR3 | 0.354 | 5.6 | 0.30816 | 0.84752 | |
RegionR4 | -0.342 | 5.6 | 0.40858 | 0.73547 | |
RegionR5 | -0.607 | 5.6 | 0.08501 | 0.27290 | |
RegionR6 | 0.124 | 5.6 | 0.72085 | 1.00000 | |
RegionR7 | -0.206 | 5.6 | 0.58858 | 1.00000 | |
RegionR8 | 0.47 | 5.6 | 0.24704 | 0.86474 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -1.234 | 5.6 | 0.34594 | 1.00000 | |
RegenerationR2 | 0.153 | 5.6 | 0.71001 | 0.95996 | |
RegenerationR3 | -0.296 | 5.6 | 0.50528 | 0.85901 | |
RegenerationR4 | -0.289 | 5.6 | 0.52721 | 0.88308 | |
RegenerationR5 | -0.468 | 5.6 | 0.29284 | 0.72095 | |
RegenerationR6 | -0.867 | 5.6 | 0.05958 | 0.30678 | |
RegenerationBL | 0.206 | 5.6 | 0.62684 | 0.96904 | |
RegenerationTP | 0.563 | 5.6 | 0.21152 | 0.65443 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_36802 | 2078 | 43.3 | Mlig455_010812 | Neo: - |
FAT1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_010812 {REF} {Length: 8313} {Pfam: Cadherin domain [PF00028.19, score=230.6]; Laminin G domain [PF02210.26, score=95.2]; Cadherin cytoplasmic region [PF01049.19, score=78.0]; Laminin G domain [PF00054.25, score=62.2]; Cadherin-like [PF16184.7, score=29.4]; Bacterial cadherin-like domain [PF17803.3, score=20.3]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=200, Expect=2e-50]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=182, Expect=5e-45]; ENSMUSG00000016028, Celsr1, cadherin, EGF LAG seven-pass G-type receptor 1, [Score=180, Expect=1e-44]; ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=176, Expect=3e-43]} {Dmel: FBgn0015609, CadN, Cadherin-N, [Score=203, Expect=9e-52]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=159, Expect=1e-38]} {Smed: dd_Smed_v6_14778_0_1, dd_Smed_v6_14778_0_1, [Score=109, Expect=1e-23]} {RNA1509_321} {RNA1310_106.1} {RNA815_46.1} |
2. | MligTC455_47198 | 2558 | 53.29 | Mlig455_027629 | Neo: - Age: - Regeneration-downregulated R6: -1.588 Regeneration-depleted R6: -1.588 |
CALML5 | 3.238 | - | - | 0.787 | 0.763 | 0.954 | 0.734 | Mlig455_027629 {REF} {Length: 1182} {Pfam: EF-hand domain pair [PF13499.8, score=89.4]; EF hand [PF00036.34, score=83.6]; EF-hand domain [PF13405.8, score=76.7]; EF hand [PF13202.8, score=71.0]; EF-hand domain pair [PF13833.8, score=47.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.4]; EF-hand domain [PF14658.8, score=23.3]; Dockerin type I domain [PF00404.20, score=21.6]; Caleosin related protein [PF05042.15, score=19.7]} {Human: ENSG00000178372, CALML5, calmodulin like 5, [Score=62.4, Expect=1e-12]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=57.4, Expect=8e-11]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=59.3, Expect=1e-11]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=68.2, Expect=3e-15]} {Smed: dd_Smed_v6_5204_0_1, dd_Smed_v6_5204_0_1, [RH, Score=117, Expect=2e-34]} {RNA1509_34897, RNA1509_5257} {RNA1310_35147, RNA1509_34897, RNA1509_5257} {RNA1509_34897, RNA1509_5257, RNA815_17506} |
3. | MligTC455_53718 | 3053 | 63.6 | Mlig455_008976 | Neo: - Age: - |
PPP3R1 | 2.581 | - | - | 0.754 | 0.856 | 0.971 | - | Mlig455_008976 {REF} {Length: 1892} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=93.1]; EF-hand domain pair [PF13499.8, score=90.1]; EF-hand domain [PF13405.8, score=77.2]; EF hand [PF13202.8, score=68.5]; EF-hand domain pair [PF13833.8, score=58.7]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=30.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.7]; EF-hand domain [PF14658.8, score=25.5]} {Human: ENSG00000221823, PPP3R1, protein phosphatase 3 regulatory subunit B, alpha, [RH, Score=285, Expect=2e-99]} {Mouse: ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [RH, Score=285, Expect=1e-99]} {Dmel: FBgn0010014, CanB, Calcineurin B, [RH, Score=277, Expect=6e-97]} {Celegans: WBGene00000554, cnb-1, Protein phosphatase 2B regulatory subunit cnb-1, [RH, Score=264, Expect=1e-91]} {Smed: dd_Smed_v6_4924_0_1, dd_Smed_v6_4924_0_1, [RH, Score=292, Expect=4e-103]} {RNA1509_14389, RNA1509_47454} {RNA1310_15040.2, RNA1509_14389, RNA1509_47454} {RNA1509_14389, RNA1509_47454, RNA815_13445.1} |
4. | MligTC455_27505 | 273 | 5.69 | Mlig455_047753 | Neo: - Age: Down-Down-Up Region-enriched R4: 3.237/0.00326 |
CASP8 | 1.858 | - | - | 0.888 | 0.970 | - | - | Mlig455_047753 {REF} {Length: 2872} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=126.5]; Ankyrin repeats (3 copies) [PF12796.9, score=73.0]; Ankyrin repeat [PF13606.8, score=54.7]; Ankyrin repeats (many copies) [PF13637.8, score=52.6]; Ankyrin repeat [PF00023.32, score=48.6]; Ankyrin repeats (many copies) [PF13857.8, score=47.1]} {Human: ENSG00000064012, CASP8, caspase 8, [Score=132, Expect=4e-32]; ENSG00000164305, CASP3, caspase 3, [Score=128, Expect=1e-32]} {Mouse: ENSMUSG00000026029, Casp8, caspase 8, [Score=135, Expect=1e-33]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=108, Expect=1e-25]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=115, Expect=3e-28]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=135, Expect=1e-35]} {RNA1509_27731} {RNA1310_10050} {RNA815_10088.1} |
5. | MligTC455_41989 | 272 | 5.66 | Mlig455_042581 | Neo: - |
1.844 | - | - | 0.954 | - | - | 0.890 | Mlig455_042581 {REF} {Length: 1911} {RNA1509_14858, RNA1509_2543} {RNA1310_14712, RNA1509_14858} {RNA1509_14858, RNA815_7645.1} | |
6. | MligTC455_36207 | 705 | 14.68 | Mlig455_050594 | Neo: - Age: Down-Up-Up |
LITAF | 1.81 | 0.847 | - | - | - | 0.963 | - | Mlig455_050594 {REF} {Length: 1183} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=85.5]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [Score=79.3, Expect=5e-19]; ENSG00000089486, CDIP1, cell death inducing p53 target 1, [Score=78.2, Expect=5e-19]; ENSG00000274336, CDIP1, cell death inducing p53 target 1, [Score=78.2, Expect=5e-19]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=85.1, Expect=2e-21]} {Dmel: FBgn0052280, CG32280, [Score=70.5, Expect=2e-16]} {Celegans: WBGene00012549, Y37D8A.8, [Score=52.8, Expect=1e-09]} {Smed: dd_Smed_v6_353_0_1, dd_Smed_v6_353_0_1, [Score=87.8, Expect=2e-23]} {RNA1509_43875} {RNA1310_38083} {RNA815_19137.1} |
7. | MligTC455_50510 | 9657 | 201.19 | Mlig455_010517, Mlig455_061819, Mlig455_061855, Mlig455_061863 | Neo: - Age: Down-Up-Down Regeneration-downregulated BL: -1.759 Regeneration-depleted BL: -1.759 |
PPP1R3B | 1.81 | - | 0.854 | - | - | 0.956 | - | Mlig455_010517 {REF} {Length: 1875} {Pfam: Carbohydrate/starch-binding module (family 21) [PF03370.15, score=63.8]; Starch/carbohydrate-binding module (family 53) [PF16760.7, score=27.0]} {Human: ENSG00000173281, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=57.4, Expect=6e-09]; ENSG00000285343, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=57.4, Expect=6e-09]} {Mouse: ENSMUSG00000072494, Ppp1r3e, protein phosphatase 1, regulatory subunit 3E, [Score=64.7, Expect=1e-11]} {Celegans: WBGene00019211, H18N23.2, Protein phosphatase 1 regulatory subunit, [Score=72.8, Expect=2e-14]} {Smed: dd_Smed_v6_1526_0_1, dd_Smed_v6_1526_0_1, [Score=58.9, Expect=6e-10]} {RNA1509_2365} {RNA1310_15793} {RNA815_6339.1} Mlig455_061819 {REF} {Length: 1875} {Pfam: Carbohydrate/starch-binding module (family 21) [PF03370.15, score=64.0]; Starch/carbohydrate-binding module (family 53) [PF16760.7, score=27.0]} {Human: ENSG00000173281, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=55.5, Expect=2e-08]; ENSG00000285343, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=55.5, Expect=2e-08]} {Mouse: ENSMUSG00000072494, Ppp1r3e, protein phosphatase 1, regulatory subunit 3E, [Score=64.3, Expect=1e-11]} {Celegans: WBGene00019211, H18N23.2, Protein phosphatase 1 regulatory subunit, [Score=70.1, Expect=1e-13]} {Smed: dd_Smed_v6_1526_0_1, dd_Smed_v6_1526_0_1, [Score=57.8, Expect=1e-09]} {RNA1509_20831, RNA1509_21113, RNA1509_2365, RNA1509_51404} {RNA1310_15793, RNA1509_20831, RNA1509_21113, RNA1509_2365, RNA1509_51404} {RNA1509_20831, RNA1509_21113, RNA1509_2365, RNA1509_51404, RNA815_6339.1} Mlig455_061855 {REF} {Length: 1862} {Pfam: Carbohydrate/starch-binding module (family 21) [PF03370.15, score=64.0]; Starch/carbohydrate-binding module (family 53) [PF16760.7, score=27.0]} {Human: ENSG00000173281, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=55.5, Expect=2e-08]; ENSG00000285343, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=55.5, Expect=2e-08]} {Mouse: ENSMUSG00000072494, Ppp1r3e, protein phosphatase 1, regulatory subunit 3E, [Score=64.3, Expect=1e-11]} {Celegans: WBGene00019211, H18N23.2, Protein phosphatase 1 regulatory subunit, [Score=70.1, Expect=1e-13]} {Smed: dd_Smed_v6_1526_0_1, dd_Smed_v6_1526_0_1, [Score=57.8, Expect=1e-09]} {RNA1509_2365, RNA1509_39538, RNA1509_59849} {RNA1310_15793, RNA1509_39538, RNA1509_59849} {RNA1509_39538, RNA1509_59849, RNA815_6339.1} Mlig455_061863 {REF} {Length: 1748} {Pfam: Carbohydrate/starch-binding module (family 21) [PF03370.15, score=58.7]; Starch/carbohydrate-binding module (family 53) [PF16760.7, score=27.1]} {Human: ENSG00000285343, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=51.6, Expect=4e-07]; ENSG00000173281, PPP1R3B, protein phosphatase 1 regulatory subunit 3B, [Score=51.6, Expect=4e-07]} {Mouse: ENSMUSG00000072494, Ppp1r3e, protein phosphatase 1, regulatory subunit 3E, [Score=64.7, Expect=9e-12]} {Celegans: WBGene00019211, H18N23.2, Protein phosphatase 1 regulatory subunit, [Score=60.8, Expect=1e-10]} {Smed: dd_Smed_v6_1526_0_1, dd_Smed_v6_1526_0_1, [Score=54.3, Expect=1e-08]} {RNA1509_2365} {RNA1310_15793} {RNA815_6339.1} |
8. | MligTC455_17312 | 1669 | 34.76 | Mlig455_011751, Mlig455_037276, Mlig455_070007 | Neo: - Age: Down-Up-Down Regeneration-depleted R6: -2.805 |
1.686 | - | - | - | - | 0.956 | 0.730 | Mlig455_011751 {REF} {Length: 1105} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.4]} {RNA1509_47792} {RNA1310_41364.1} {RNA815_18441} Mlig455_037276 {REF} {Length: 1193} {RNA1509_34157, RNA1509_47792} {RNA1310_41364.2, RNA1509_34157} {RNA1509_34157, RNA815_18441} Mlig455_070007 {REF} {Length: 1139} {RNA1509_47792} {RNA1310_41364.1, RNA1509_47792} {RNA1509_47792, RNA815_18441} |
|
9. | MligTC455_29904 | 179 | 3.73 | Mlig455_047055 | Neo: - |
MAP3K4 | 0.967 | - | - | - | 0.967 | - | - | Mlig455_047055 {REF} {Length: 3991} {Pfam: Protein kinase domain [PF00069.27, score=316.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=241.4]; Fungal protein kinase [PF17667.3, score=53.7]; ABC1 atypical kinase-like domain [PF03109.18, score=35.6]; Phosphotransferase enzyme family [PF01636.25, score=34.3]; Ankyrin repeat [PF13606.8, score=24.2]; Kinase-like [PF14531.8, score=24.2]; Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ternary complex associated domain 9 [PF19974.1, score=22.5]; Seadornavirus VP7 [PF07387.13, score=20.7]; Ankyrin repeat [PF00023.32, score=20.0]; Ankyrin repeats (many copies) [PF13857.8, score=19.9]; Choline/ethanolamine kinase [PF01633.22, score=18.5]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=132, Expect=5e-31]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=127, Expect=2e-30]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=132, Expect=5e-32]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=7e-30]} {Dmel: FBgn0024329, Mekk1, [Score=124, Expect=2e-28]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=129, Expect=2e-30]} {Smed: dd_Smed_v6_9379_0_2, dd_Smed_v6_9379_0_2, [Score=121, Expect=2e-28]} {RNA1509_39395} {RNA1310_23280} {RNA815_6977.2} |
10. | MligTC455_47211 | 85 | 1.78 | Mlig455_018955 | Neo: - |
0.964 | - | - | - | - | - | 0.964 | Mlig455_018955 {REF} {Length: 2980} {RNA1509_2043} {RNA1310_23078} {RNA815_8099.1} | |
11. | MligTC455_42486 | 52 | 1.09 | Mlig455_056354 | Neo: - Age: - |
0.957 | - | - | - | - | 0.957 | - | Mlig455_056354 {REF} {Length: 1240} | |
12. | MligTC455_27657 | 45 | 0.94 | Mlig455_016973 | Neo: - Age: - |
0.954 | - | - | - | - | 0.954 | - | Mlig455_016973 {REF} {Length: 2932} {Pfam: RNase H [PF00075.26, score=57.3]} {RNA1509_5045} {RNA1310_5000.1} {RNA815_8147} | |
13. | MligTC455_42704 | 286 | 5.96 | Mlig455_005126, Mlig455_005184 | Neo: - |
0.954 | - | - | 0.954 | - | - | - | Mlig455_005126 {REF} {Length: 1265} {Smed: dd_Smed_v6_14508_0_1, dd_Smed_v6_14508_0_1, [Score=67.8, Expect=2e-14]} {RNA1509_40048} {RNA1310_26195} {RNA815_29753} Mlig455_005184 {REF} {Length: 1185} {Smed: dd_Smed_v6_14508_0_1, dd_Smed_v6_14508_0_1, [Score=67.8, Expect=2e-14]} {RNA1509_40048} {RNA1310_26195} {RNA815_29753} |
|
14. | MligTC455_40307 | 446 | 9.28 | Mlig455_018587 | Neo: - Age: - |
PPHLN1 | 0.953 | - | - | - | 0.953 | - | - | Mlig455_018587 {REF} {Length: 3799} {TRANSSPLICED} {Pfam: Transcriptional regulatory protein LGE1 [PF11488.10, score=35.5]} {Human: ENSG00000134283, PPHLN1, periphilin 1, [Score=72.8, Expect=1e-13]} {Mouse: ENSMUSG00000079737, 3110001I22Rik, RIKEN cDNA 3110001I22 gene, [RH, Score=72.8, Expect=5e-14]} {Celegans: WBGene00013307, Y57G11C.9, [RH, Score=71.2, Expect=2e-13]} {Smed: dd_Smed_v6_3002_0_1, dd_Smed_v6_3002_0_1, [RH, Score=100, Expect=4e-23]} {RNA1509_18724, RNA1509_42934, RNA1509_53063} {RNA1310_19874, RNA1509_18724, RNA1509_42934, RNA1509_53063} {RNA1509_18724, RNA1509_42934, RNA1509_53063, RNA815_22742} |
15. | MligTC455_53013 | 60 | 1.26 | Mlig455_054106 | Neo: - Age: Down-Down-Up |
0.951 | - | - | - | 0.951 | - | - | Mlig455_054106 {REF} {Length: 1237} {TRANSSPLICED} {RNA1509_24093} {RNA1310_63179} {RNA815_13022.1} | |
16. | MligTC455_18425 | 65 | 1.35 | Mlig455_070253 | Neo: - |
0.95 | - | - | - | 0.950 | - | - | Mlig455_070253 {REF} {Length: 1630} {RNA1509_32615} {RNA1310_20631.1} {RNA815_8350} |