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Results for MligTC455_37379

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_37379 1312 27.33 Mlig455_063552

Neo: -

Age: logFC(26M/2M)=0.263

Region-enriched R4: 1.276/0.01237

ALPK1 Mlig455_063552 {REF} {Length: 2442} {Pfam: Alpha-kinase family [PF02816.20, score=126.9]; von Willebrand factor type A domain [PF13519.8, score=22.7]} {Human: ENSG00000073331, ALPK1, alpha kinase 1, [Score=70.9, Expect=5e-12]} {Mouse: ENSMUSG00000024727, Trpm6, transient receptor potential cation channel, subfamily M, member 6, [Score=67.0, Expect=5e-11]; ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=64.3, Expect=3e-10]; ENSMUSG00000028028, Alpk1, alpha-kinase 1, [Score=64.3, Expect=4e-10]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [Score=59.7, Expect=4e-09]} {Smed: dd_Smed_v6_2651_0_1, dd_Smed_v6_2651_0_1, [Score=65.9, Expect=5e-11]} {RNA1509_2701} {RNA1310_9958, RNA1509_2701} {RNA1509_2701, RNA815_3448}

Cumulative graph for MligTC455_37379

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.815 4.954 0.31675 0.96596
RegionR2 -1.472 4.954 0.00063 0.01572
RegionR3 0.081 4.954 0.80916 1.00000
RegionR4 1.276 4.954 0.00125 0.01237
RegionR5 0.054 4.954 0.86436 1.00000
RegionR6 0.075 4.954 0.82416 1.00000
RegionR7 -0.455 4.954 0.30843 0.94260
RegionR8 -0.373 4.954 0.50565 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.665 4.954 0.17622 0.91858
RegenerationR2 0.046 4.954 0.90775 1.00000
RegenerationR3 0.104 4.954 0.79058 0.97902
RegenerationR4 -0.444 4.954 0.27113 0.71719
RegenerationR5 0.27 4.954 0.47154 0.84256
RegenerationR6 0.615 4.954 0.11774 0.42197
RegenerationBL 0.057 4.954 0.89679 1.00000
RegenerationTP 0.46 4.954 0.34598 0.78784


Genes with expression patterns similar to MligTC455_37379

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_37379 1312 27.33 Mlig455_063552

Neo: -

Age: logFC(26M/2M)=0.263

Region-enriched R4: 1.276/0.01237

ALPK1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_063552 {REF} {Length: 2442} {Pfam: Alpha-kinase family [PF02816.20, score=126.9]; von Willebrand factor type A domain [PF13519.8, score=22.7]} {Human: ENSG00000073331, ALPK1, alpha kinase 1, [Score=70.9, Expect=5e-12]} {Mouse: ENSMUSG00000024727, Trpm6, transient receptor potential cation channel, subfamily M, member 6, [Score=67.0, Expect=5e-11]; ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=64.3, Expect=3e-10]; ENSMUSG00000028028, Alpk1, alpha-kinase 1, [Score=64.3, Expect=4e-10]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [Score=59.7, Expect=4e-09]} {Smed: dd_Smed_v6_2651_0_1, dd_Smed_v6_2651_0_1, [Score=65.9, Expect=5e-11]} {RNA1509_2701} {RNA1310_9958, RNA1509_2701} {RNA1509_2701, RNA815_3448}
2. MligTC455_26422 558 11.63 Mlig455_006604

Neo: -

Age: Up-Down-Down

RAPGEF6 1.66 - - - 0.710 - 0.950 Mlig455_006604 {REF} {Length: 5327} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=127.5]; PDZ domain [PF17820.3, score=36.1]; RasGEF N-terminal motif [PF00618.22, score=30.2]; PDZ domain [PF00595.26, score=30.0]; Cyclic nucleotide-binding domain [PF00027.31, score=25.6]; Ras association (RalGDS/AF-6) domain [PF00788.25, score=24.0]; PDZ domain [PF13180.8, score=22.9]} {Human: ENSG00000158987, RAPGEF6, Rap guanine nucleotide exchange factor 6, [RH, Score=477, Expect=3e-145]; ENSG00000273217, AC008695.1, novel protein, [RH, Score=474, Expect=2e-142]; ENSG00000109756, RAPGEF2, Rap guanine nucleotide exchange factor 2, [RH, Score=474, Expect=2e-143]} {Mouse: ENSMUSG00000037533, Rapgef6, Rap guanine nucleotide exchange factor (GEF) 6, [RH, Score=478, Expect=4e-144]; ENSMUSG00000062232, Rapgef2, Rap guanine nucleotide exchange factor (GEF) 2, [RH, Score=474, Expect=9e-144]} {Dmel: FBgn0265778, PDZ-GEF, PDZ domain-containing guanine nucleotide exchange factor, [RH, Score=261, Expect=1e-70]} {Celegans: WBGene00004254, pxf-1, Rap guanine nucleotide exchange factor, [RH, Score=221, Expect=4e-58]} {Smed: dd_Smed_v6_4950_0_3, dd_Smed_v6_4950_0_3, [RH, Score=436, Expect=9e-130]} {RNA1509_33540} {RNA1310_804.1, RNA1509_33540} {RNA1509_33540, RNA815_1044}
3. MligTC455_44997 350 7.3 Mlig455_067391

Neo: -

Age: Down-Up-Down

Region-enriched R3: 1.898/0.03879

AADAC 0.968 - - - - - 0.968 Mlig455_067391 {REF} {Length: 2287} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=182.3]; Carboxylesterase family [PF00135.30, score=28.4]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [RH, Score=152, Expect=9e-42]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [RH, Score=152, Expect=8e-42]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [RH, Score=149, Expect=7e-41]; ENSMUSG00000091376, Aadacl2, arylacetamide deacetylase like 2, [RH, Score=149, Expect=7e-41]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=53.9, Expect=1e-07]} {Celegans: WBGene00017515, F16F9.4, [RH, Score=158, Expect=2e-44]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [RH, Score=158, Expect=1e-44]} {RNA1509_14170} {RNA1310_24754} {RNA815_11905}
4. MligTC455_36089 867 18.05 Mlig455_035111, Mlig455_062422

Neo: -

Age: -

ACSS1 0.967 - - - - - 0.967

Mlig455_035111 {REF} {Length: 2972} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=271.7]; AMP-binding enzyme C-terminal domain [PF13193.8, score=89.2]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=39.6]} {Human: ENSG00000154930, ACSS1, acyl-CoA synthetase short chain family member 1, [RH, Score=733, Expect=0.0]} {Mouse: ENSMUSG00000027452, Acss1, acyl-CoA synthetase short-chain family member 1, [RH, Score=748, Expect=0.0]} {Dmel: FBgn0012034, AcCoAS, Acetyl Coenzyme A synthase, [Score=526, Expect=2e-179]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=491, Expect=5e-166]} {Smed: dd_Smed_v6_6561_0_1, dd_Smed_v6_6561_0_1, [RH, Score=717, Expect=0.0]} {RNA1509_44916} {RNA1310_11929} {RNA815_3848}

Mlig455_062422 {REF} {Length: 2961} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=287.6]; AMP-binding enzyme C-terminal domain [PF13193.8, score=89.2]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=40.0]} {Human: ENSG00000154930, ACSS1, acyl-CoA synthetase short chain family member 1, [RH, Score=742, Expect=0.0]} {Mouse: ENSMUSG00000027452, Acss1, acyl-CoA synthetase short-chain family member 1, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0012034, AcCoAS, Acetyl Coenzyme A synthase, [Score=533, Expect=0.0]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=500, Expect=2e-169]} {Smed: dd_Smed_v6_6561_0_1, dd_Smed_v6_6561_0_1, [RH, Score=720, Expect=0.0]} {RNA1509_44916} {RNA1310_11929} {RNA815_3848}
5. MligTC455_45420 2046 42.62 Mlig455_056064, Mlig455_061586

Neo: -

Age: -

Region-enriched R3: 2.079/0.03891

0.959 - - - - - 0.959

Mlig455_056064 {REF} {Length: 1343} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_9020} {RNA1310_25351.3} {RNA815_8070}

Mlig455_061586 {REF} {Length: 1849} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_48946, RNA1509_9020} {RNA1310_25351.3, RNA1509_48946, RNA1509_9020} {RNA1509_48946, RNA1509_9020, RNA815_8070}
6. MligTC455_39815 586 12.2 Mlig455_022414

Neo: -

Age: -

GRAMD2B 0.954 - - - - - 0.954 Mlig455_022414 {REF} {Length: 3008} {Pfam: GRAM domain [PF02893.22, score=57.7]} {Human: ENSG00000155324, GRAMD2B, GRAM domain containing 2B, [RH, Score=92.0, Expect=5e-20]} {Mouse: ENSMUSG00000001700, Gramd3, GRAM domain containing 3, [RH, Score=93.2, Expect=1e-20]} {Dmel: FBgn0085423, CG34394, [Score=90.1, Expect=2e-19]} {Celegans: WBGene00022593, ZC328.3, [Score=62.8, Expect=1e-10]} {Smed: dd_Smed_v6_8544_1_1, dd_Smed_v6_8544_1_1, [RH, Score=124, Expect=4e-32]} {RNA1509_31678} {RNA1310_9711.1} {RNA815_8169}
7. MligTC455_36919 134 2.79 Mlig455_040211

Neo: -

Age: -

Region-enriched R7: 2.837/0.02063

Regeneration-downregulated TP: -7.378

Regeneration-depleted TP: -7.378

ERBB2 0.952 - - - - 0.952 - Mlig455_040211 {REF} {Length: 5317} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=262.1]; Protein kinase domain [PF00069.27, score=135.7]; Furin-like cysteine rich region [PF00757.22, score=67.4]; Growth factor receptor domain IV [PF14843.8, score=58.4]; Receptor L domain [PF01030.26, score=35.0]; Kinase-like [PF14531.8, score=20.3]} {Human: ENSG00000141736, ERBB2, erb-b2 receptor tyrosine kinase 2, [RH, Score=400, Expect=1e-119]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=418, Expect=1e-125]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=276, Expect=3e-76]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=254, Expect=4e-69]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=296, Expect=8e-83]} {RNA1509_4668} {RNA1310_1923.2} {RNA815_5649.1}
8. MligTC455_50420 1582 32.96 Mlig455_044844, Mlig455_044936

Neo: -

Age: logFC(26M/2M)=-0.481

SLC5A12 0.951 - - - - - 0.951

Mlig455_044844 {REF} {Length: 3138} {Pfam: Sodium:solute symporter family [PF00474.19, score=96.2]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=305, Expect=4e-95]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=298, Expect=3e-92]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=298, Expect=3e-92]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=294, Expect=1e-90]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=300, Expect=2e-93]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=297, Expect=3e-92]; ENSMUSG00000006641, Slc5a6, solute carrier family 5 (sodium-dependent vitamin transporter), member 6, [Score=290, Expect=2e-89]} {Dmel: FBgn0034494, CG10444, [Score=280, Expect=5e-86]} {Celegans: WBGene00014092, ZK822.5, [Score=215, Expect=5e-62]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=285, Expect=2e-88]} {RNA1509_18508} {RNA1310_13650.1} {RNA815_10147}

Mlig455_044936 {REF} {Length: 3192} {Pfam: Sodium:solute symporter family [PF00474.19, score=99.0]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=306, Expect=2e-95]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=299, Expect=1e-92]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=299, Expect=1e-92]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=298, Expect=6e-92]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=301, Expect=8e-94]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=299, Expect=7e-93]; ENSMUSG00000006641, Slc5a6, solute carrier family 5 (sodium-dependent vitamin transporter), member 6, [Score=291, Expect=1e-89]} {Dmel: FBgn0034494, CG10444, [Score=281, Expect=2e-86]} {Celegans: WBGene00014092, ZK822.5, [Score=217, Expect=1e-62]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=287, Expect=4e-89]} {RNA1509_18508, RNA1509_21413} {RNA1310_13650.1, RNA1509_18508, RNA1509_21413} {RNA1509_18508, RNA1509_21413, RNA815_10147}

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