Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_37379 | 1312 | 27.33 | Mlig455_063552 | Neo: - Age: logFC(26M/2M)=0.263 Region-enriched R4: 1.276/0.01237 |
ALPK1 | Mlig455_063552 {REF} {Length: 2442} {Pfam: Alpha-kinase family [PF02816.20, score=126.9]; von Willebrand factor type A domain [PF13519.8, score=22.7]} {Human: ENSG00000073331, ALPK1, alpha kinase 1, [Score=70.9, Expect=5e-12]} {Mouse: ENSMUSG00000024727, Trpm6, transient receptor potential cation channel, subfamily M, member 6, [Score=67.0, Expect=5e-11]; ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=64.3, Expect=3e-10]; ENSMUSG00000028028, Alpk1, alpha-kinase 1, [Score=64.3, Expect=4e-10]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [Score=59.7, Expect=4e-09]} {Smed: dd_Smed_v6_2651_0_1, dd_Smed_v6_2651_0_1, [Score=65.9, Expect=5e-11]} {RNA1509_2701} {RNA1310_9958, RNA1509_2701} {RNA1509_2701, RNA815_3448} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.815 | 4.954 | 0.31675 | 0.96596 | |
RegionR2 | -1.472 | 4.954 | 0.00063 | 0.01572 | |
RegionR3 | 0.081 | 4.954 | 0.80916 | 1.00000 | |
RegionR4 | 1.276 | 4.954 | 0.00125 | 0.01237 | |
RegionR5 | 0.054 | 4.954 | 0.86436 | 1.00000 | |
RegionR6 | 0.075 | 4.954 | 0.82416 | 1.00000 | |
RegionR7 | -0.455 | 4.954 | 0.30843 | 0.94260 | |
RegionR8 | -0.373 | 4.954 | 0.50565 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -1.665 | 4.954 | 0.17622 | 0.91858 | |
RegenerationR2 | 0.046 | 4.954 | 0.90775 | 1.00000 | |
RegenerationR3 | 0.104 | 4.954 | 0.79058 | 0.97902 | |
RegenerationR4 | -0.444 | 4.954 | 0.27113 | 0.71719 | |
RegenerationR5 | 0.27 | 4.954 | 0.47154 | 0.84256 | |
RegenerationR6 | 0.615 | 4.954 | 0.11774 | 0.42197 | |
RegenerationBL | 0.057 | 4.954 | 0.89679 | 1.00000 | |
RegenerationTP | 0.46 | 4.954 | 0.34598 | 0.78784 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_37379 | 1312 | 27.33 | Mlig455_063552 | Neo: - Age: logFC(26M/2M)=0.263 Region-enriched R4: 1.276/0.01237 |
ALPK1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_063552 {REF} {Length: 2442} {Pfam: Alpha-kinase family [PF02816.20, score=126.9]; von Willebrand factor type A domain [PF13519.8, score=22.7]} {Human: ENSG00000073331, ALPK1, alpha kinase 1, [Score=70.9, Expect=5e-12]} {Mouse: ENSMUSG00000024727, Trpm6, transient receptor potential cation channel, subfamily M, member 6, [Score=67.0, Expect=5e-11]; ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=64.3, Expect=3e-10]; ENSMUSG00000028028, Alpk1, alpha-kinase 1, [Score=64.3, Expect=4e-10]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [Score=59.7, Expect=4e-09]} {Smed: dd_Smed_v6_2651_0_1, dd_Smed_v6_2651_0_1, [Score=65.9, Expect=5e-11]} {RNA1509_2701} {RNA1310_9958, RNA1509_2701} {RNA1509_2701, RNA815_3448} |
2. | MligTC455_26422 | 558 | 11.63 | Mlig455_006604 | Neo: - Age: Up-Down-Down |
RAPGEF6 | 1.66 | - | - | - | 0.710 | - | 0.950 | Mlig455_006604 {REF} {Length: 5327} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=127.5]; PDZ domain [PF17820.3, score=36.1]; RasGEF N-terminal motif [PF00618.22, score=30.2]; PDZ domain [PF00595.26, score=30.0]; Cyclic nucleotide-binding domain [PF00027.31, score=25.6]; Ras association (RalGDS/AF-6) domain [PF00788.25, score=24.0]; PDZ domain [PF13180.8, score=22.9]} {Human: ENSG00000158987, RAPGEF6, Rap guanine nucleotide exchange factor 6, [RH, Score=477, Expect=3e-145]; ENSG00000273217, AC008695.1, novel protein, [RH, Score=474, Expect=2e-142]; ENSG00000109756, RAPGEF2, Rap guanine nucleotide exchange factor 2, [RH, Score=474, Expect=2e-143]} {Mouse: ENSMUSG00000037533, Rapgef6, Rap guanine nucleotide exchange factor (GEF) 6, [RH, Score=478, Expect=4e-144]; ENSMUSG00000062232, Rapgef2, Rap guanine nucleotide exchange factor (GEF) 2, [RH, Score=474, Expect=9e-144]} {Dmel: FBgn0265778, PDZ-GEF, PDZ domain-containing guanine nucleotide exchange factor, [RH, Score=261, Expect=1e-70]} {Celegans: WBGene00004254, pxf-1, Rap guanine nucleotide exchange factor, [RH, Score=221, Expect=4e-58]} {Smed: dd_Smed_v6_4950_0_3, dd_Smed_v6_4950_0_3, [RH, Score=436, Expect=9e-130]} {RNA1509_33540} {RNA1310_804.1, RNA1509_33540} {RNA1509_33540, RNA815_1044} |
3. | MligTC455_44997 | 350 | 7.3 | Mlig455_067391 | Neo: - Age: Down-Up-Down Region-enriched R3: 1.898/0.03879 |
AADAC | 0.968 | - | - | - | - | - | 0.968 | Mlig455_067391 {REF} {Length: 2287} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=182.3]; Carboxylesterase family [PF00135.30, score=28.4]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [RH, Score=152, Expect=9e-42]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [RH, Score=152, Expect=8e-42]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [RH, Score=149, Expect=7e-41]; ENSMUSG00000091376, Aadacl2, arylacetamide deacetylase like 2, [RH, Score=149, Expect=7e-41]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=53.9, Expect=1e-07]} {Celegans: WBGene00017515, F16F9.4, [RH, Score=158, Expect=2e-44]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [RH, Score=158, Expect=1e-44]} {RNA1509_14170} {RNA1310_24754} {RNA815_11905} |
4. | MligTC455_36089 | 867 | 18.05 | Mlig455_035111, Mlig455_062422 | Neo: - Age: - |
ACSS1 | 0.967 | - | - | - | - | - | 0.967 | Mlig455_035111 {REF} {Length: 2972} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=271.7]; AMP-binding enzyme C-terminal domain [PF13193.8, score=89.2]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=39.6]} {Human: ENSG00000154930, ACSS1, acyl-CoA synthetase short chain family member 1, [RH, Score=733, Expect=0.0]} {Mouse: ENSMUSG00000027452, Acss1, acyl-CoA synthetase short-chain family member 1, [RH, Score=748, Expect=0.0]} {Dmel: FBgn0012034, AcCoAS, Acetyl Coenzyme A synthase, [Score=526, Expect=2e-179]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=491, Expect=5e-166]} {Smed: dd_Smed_v6_6561_0_1, dd_Smed_v6_6561_0_1, [RH, Score=717, Expect=0.0]} {RNA1509_44916} {RNA1310_11929} {RNA815_3848} Mlig455_062422 {REF} {Length: 2961} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=287.6]; AMP-binding enzyme C-terminal domain [PF13193.8, score=89.2]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=40.0]} {Human: ENSG00000154930, ACSS1, acyl-CoA synthetase short chain family member 1, [RH, Score=742, Expect=0.0]} {Mouse: ENSMUSG00000027452, Acss1, acyl-CoA synthetase short-chain family member 1, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0012034, AcCoAS, Acetyl Coenzyme A synthase, [Score=533, Expect=0.0]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=500, Expect=2e-169]} {Smed: dd_Smed_v6_6561_0_1, dd_Smed_v6_6561_0_1, [RH, Score=720, Expect=0.0]} {RNA1509_44916} {RNA1310_11929} {RNA815_3848} |
5. | MligTC455_45420 | 2046 | 42.62 | Mlig455_056064, Mlig455_061586 | Neo: - Age: - Region-enriched R3: 2.079/0.03891 |
0.959 | - | - | - | - | - | 0.959 | Mlig455_056064 {REF} {Length: 1343} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_9020} {RNA1310_25351.3} {RNA815_8070} Mlig455_061586 {REF} {Length: 1849} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_48946, RNA1509_9020} {RNA1310_25351.3, RNA1509_48946, RNA1509_9020} {RNA1509_48946, RNA1509_9020, RNA815_8070} |
|
6. | MligTC455_39815 | 586 | 12.2 | Mlig455_022414 | Neo: - Age: - |
GRAMD2B | 0.954 | - | - | - | - | - | 0.954 | Mlig455_022414 {REF} {Length: 3008} {Pfam: GRAM domain [PF02893.22, score=57.7]} {Human: ENSG00000155324, GRAMD2B, GRAM domain containing 2B, [RH, Score=92.0, Expect=5e-20]} {Mouse: ENSMUSG00000001700, Gramd3, GRAM domain containing 3, [RH, Score=93.2, Expect=1e-20]} {Dmel: FBgn0085423, CG34394, [Score=90.1, Expect=2e-19]} {Celegans: WBGene00022593, ZC328.3, [Score=62.8, Expect=1e-10]} {Smed: dd_Smed_v6_8544_1_1, dd_Smed_v6_8544_1_1, [RH, Score=124, Expect=4e-32]} {RNA1509_31678} {RNA1310_9711.1} {RNA815_8169} |
7. | MligTC455_36919 | 134 | 2.79 | Mlig455_040211 | Neo: - Age: - Region-enriched R7: 2.837/0.02063 Regeneration-downregulated TP: -7.378 Regeneration-depleted TP: -7.378 |
ERBB2 | 0.952 | - | - | - | - | 0.952 | - | Mlig455_040211 {REF} {Length: 5317} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=262.1]; Protein kinase domain [PF00069.27, score=135.7]; Furin-like cysteine rich region [PF00757.22, score=67.4]; Growth factor receptor domain IV [PF14843.8, score=58.4]; Receptor L domain [PF01030.26, score=35.0]; Kinase-like [PF14531.8, score=20.3]} {Human: ENSG00000141736, ERBB2, erb-b2 receptor tyrosine kinase 2, [RH, Score=400, Expect=1e-119]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=418, Expect=1e-125]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=276, Expect=3e-76]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=254, Expect=4e-69]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=296, Expect=8e-83]} {RNA1509_4668} {RNA1310_1923.2} {RNA815_5649.1} |
8. | MligTC455_50420 | 1582 | 32.96 | Mlig455_044844, Mlig455_044936 | Neo: - Age: logFC(26M/2M)=-0.481 |
SLC5A12 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_044844 {REF} {Length: 3138} {Pfam: Sodium:solute symporter family [PF00474.19, score=96.2]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=305, Expect=4e-95]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=298, Expect=3e-92]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=298, Expect=3e-92]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=294, Expect=1e-90]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=300, Expect=2e-93]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=297, Expect=3e-92]; ENSMUSG00000006641, Slc5a6, solute carrier family 5 (sodium-dependent vitamin transporter), member 6, [Score=290, Expect=2e-89]} {Dmel: FBgn0034494, CG10444, [Score=280, Expect=5e-86]} {Celegans: WBGene00014092, ZK822.5, [Score=215, Expect=5e-62]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=285, Expect=2e-88]} {RNA1509_18508} {RNA1310_13650.1} {RNA815_10147} Mlig455_044936 {REF} {Length: 3192} {Pfam: Sodium:solute symporter family [PF00474.19, score=99.0]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=306, Expect=2e-95]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=299, Expect=1e-92]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=299, Expect=1e-92]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=298, Expect=6e-92]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=301, Expect=8e-94]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=299, Expect=7e-93]; ENSMUSG00000006641, Slc5a6, solute carrier family 5 (sodium-dependent vitamin transporter), member 6, [Score=291, Expect=1e-89]} {Dmel: FBgn0034494, CG10444, [Score=281, Expect=2e-86]} {Celegans: WBGene00014092, ZK822.5, [Score=217, Expect=1e-62]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=287, Expect=4e-89]} {RNA1509_18508, RNA1509_21413} {RNA1310_13650.1, RNA1509_18508, RNA1509_21413} {RNA1509_18508, RNA1509_21413, RNA815_10147} |