Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_36919 | 134 | 2.79 | Mlig455_040211 | Neo: - Age: - Region-enriched R7: 2.837/0.02063 Regeneration-downregulated TP: -7.378 Regeneration-depleted TP: -7.378 |
ERBB2 | Mlig455_040211 {REF} {Length: 5317} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=262.1]; Protein kinase domain [PF00069.27, score=135.7]; Furin-like cysteine rich region [PF00757.22, score=67.4]; Growth factor receptor domain IV [PF14843.8, score=58.4]; Receptor L domain [PF01030.26, score=35.0]; Kinase-like [PF14531.8, score=20.3]} {Human: ENSG00000141736, ERBB2, erb-b2 receptor tyrosine kinase 2, [RH, Score=400, Expect=1e-119]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=418, Expect=1e-125]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=276, Expect=3e-76]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=254, Expect=4e-69]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=296, Expect=8e-83]} {RNA1509_4668} {RNA1310_1923.2} {RNA815_5649.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -5.086 | 2.152 | 0.28857 | 0.94106 | |
RegionR2 | 0.957 | 2.152 | 0.38564 | 0.78032 | |
RegionR3 | 0.305 | 2.152 | 0.72397 | 1.00000 | |
RegionR4 | -0.452 | 2.152 | 0.95443 | 1.00000 | |
RegionR5 | -0.369 | 2.152 | 0.94402 | 1.00000 | |
RegionR6 | 0.213 | 2.152 | 0.77577 | 1.00000 | |
RegionR7 | 2.837 | 2.152 | 0.00050 | 0.02063 | |
RegionR8 | 1.595 | 2.152 | 0.23275 | 0.84689 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -1.14 | 2.152 | 0.99995 | 1.00000 | |
RegenerationR2 | -2.927 | 2.152 | 0.00015 | 0.01471 | |
RegenerationR3 | -2.086 | 2.152 | 0.00773 | 0.16099 | |
RegenerationR4 | -1.974 | 2.152 | 0.01447 | 0.18835 | |
RegenerationR5 | -2.452 | 2.152 | 0.00145 | 0.06539 | |
RegenerationR6 | -1.637 | 2.152 | 0.03992 | 0.24994 | |
RegenerationBL | -2.601 | 2.152 | 0.01146 | 0.10907 | |
RegenerationTP | -7.378 | 2.152 | 0.00006 | 0.00818 | Specific for TP: -7.378 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_36919 | 134 | 2.79 | Mlig455_040211 | Neo: - Age: - Region-enriched R7: 2.837/0.02063 Regeneration-downregulated TP: -7.378 Regeneration-depleted TP: -7.378 |
ERBB2 | 4 | 1.000 | 1.000 | 1.000 | - | 1.000 | - | Mlig455_040211 {REF} {Length: 5317} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=262.1]; Protein kinase domain [PF00069.27, score=135.7]; Furin-like cysteine rich region [PF00757.22, score=67.4]; Growth factor receptor domain IV [PF14843.8, score=58.4]; Receptor L domain [PF01030.26, score=35.0]; Kinase-like [PF14531.8, score=20.3]} {Human: ENSG00000141736, ERBB2, erb-b2 receptor tyrosine kinase 2, [RH, Score=400, Expect=1e-119]} {Mouse: ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=418, Expect=1e-125]} {Dmel: FBgn0003731, Egfr, Epidermal growth factor receptor, [Score=276, Expect=3e-76]} {Celegans: WBGene00002299, let-23, Receptor tyrosine-protein kinase let-23, [Score=254, Expect=4e-69]} {Smed: dd_Smed_v6_11310_0_1, dd_Smed_v6_11310_0_1, [Score=296, Expect=8e-83]} {RNA1509_4668} {RNA1310_1923.2} {RNA815_5649.1} |
2. | MligTC455_25472 | 100 | 2.07 | Mlig455_040494 | Neo: - Age: Up-Up-Down |
RAPH1 | 0.962 | - | - | - | - | 0.962 | - | Mlig455_040494 {REF} {Length: 1705} {Pfam: PH domain [PF00169.31, score=40.6]} {Human: ENSG00000173166, RAPH1, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1, [Score=107, Expect=2e-26]} {Mouse: ENSMUSG00000026014, Raph1, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1, [Score=104, Expect=7e-26]} {Dmel: FBgn0261811, pico, [Score=88.2, Expect=4e-20]} {Celegans: WBGene00003243, mig-10, Abnormal cell migration protein 10, [Score=90.5, Expect=3e-21]} {Smed: dd_Smed_v6_3216_0_1, dd_Smed_v6_3216_0_1, [Score=120, Expect=9e-32]} {RNA1509_24403} {RNA1310_12419} {RNA815_13072} |
3. | MligTC455_37379 | 1312 | 27.33 | Mlig455_063552 | Neo: - Age: logFC(26M/2M)=0.263 Region-enriched R4: 1.276/0.01237 |
ALPK1 | 0.952 | - | - | - | - | 0.952 | - | Mlig455_063552 {REF} {Length: 2442} {Pfam: Alpha-kinase family [PF02816.20, score=126.9]; von Willebrand factor type A domain [PF13519.8, score=22.7]} {Human: ENSG00000073331, ALPK1, alpha kinase 1, [Score=70.9, Expect=5e-12]} {Mouse: ENSMUSG00000024727, Trpm6, transient receptor potential cation channel, subfamily M, member 6, [Score=67.0, Expect=5e-11]; ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=64.3, Expect=3e-10]; ENSMUSG00000028028, Alpk1, alpha-kinase 1, [Score=64.3, Expect=4e-10]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [Score=59.7, Expect=4e-09]} {Smed: dd_Smed_v6_2651_0_1, dd_Smed_v6_2651_0_1, [Score=65.9, Expect=5e-11]} {RNA1509_2701} {RNA1310_9958, RNA1509_2701} {RNA1509_2701, RNA815_3448} |
4. | MligTC455_43278 | 1082 | 22.55 | Mlig455_029717 | Neo: Neoblast Age: logFC(26M/2M)=0.298 |
0.951 | - | - | - | - | 0.951 | - | Mlig455_029717 {REF} {Length: 2174} {TRANSSPLICED} {RNA1509_8103} {RNA1310_6457, RNA1509_8103} {RNA1509_8103, RNA815_11775} |