Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_39066 | 7621 | 158.77 | Mlig455_003483 | Neo: - Age: logFC(26M/2M)=-0.600 Regeneration-downregulated BL: -1.940 Regeneration-depleted BL: -1.940 |
GSTP1 | Mlig455_003483 {REF} {Length: 1133} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=56.7]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=33.6]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=26.4]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=26.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=20.4]; Glutathione S-transferase N-terminal domain [PF17172.6, score=20.3]} {Human: ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=139, Expect=1e-40]} {Mouse: ENSMUSG00000097830, Gstp1, glutathione S-transferase, pi 1, [RH, Score=144, Expect=8e-43]; ENSMUSG00000060803, Gstp1, glutathione S-transferase, pi 1, [RH, Score=144, Expect=8e-43]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [RH, Score=99.8, Expect=2e-25]} {Celegans: WBGene00001749, gst-1, Glutathione S-transferase P, [RH, Score=147, Expect=1e-44]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=96.3, Expect=7e-25]} {RNA1509_37855, RNA1509_42842, RNA1509_53728, RNA1509_6171} {RNA1310_28502.1, RNA1509_37855, RNA1509_42842, RNA1509_53728, RNA1509_6171} {RNA1509_37855, RNA1509_42842, RNA1509_53728, RNA1509_6171, RNA815_13314} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.585 | 7.37 | 0.00597 | 0.23875 | |
RegionR2 | 0.16 | 7.37 | 0.69787 | 1.00000 | |
RegionR3 | 0.669 | 7.37 | 0.05391 | 0.40671 | |
RegionR4 | 0.163 | 7.37 | 0.68813 | 0.98001 | |
RegionR5 | -0.14 | 7.37 | 0.69609 | 1.00000 | |
RegionR6 | -0.023 | 7.37 | 0.94913 | 1.00000 | |
RegionR7 | 0.96 | 7.37 | 0.00429 | 0.09855 | |
RegionR8 | -0.205 | 7.37 | 0.60881 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.332 | 7.37 | 0.62466 | 1.00000 | |
RegenerationR2 | -0.683 | 7.37 | 0.14077 | 0.57017 | |
RegenerationR3 | -0.419 | 7.37 | 0.37629 | 0.78804 | |
RegenerationR4 | -0.898 | 7.37 | 0.06220 | 0.39925 | |
RegenerationR5 | -0.4 | 7.37 | 0.38639 | 0.78966 | |
RegenerationR6 | -0.969 | 7.37 | 0.04064 | 0.25217 | |
RegenerationBL | -1.94 | 7.37 | 0.00002 | 0.00142 | Specific for BL: -1.940 |
RegenerationTP | 0.798 | 7.37 | 0.05873 | 0.39301 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_39066 | 7621 | 158.77 | Mlig455_003483 | Neo: - Age: logFC(26M/2M)=-0.600 Regeneration-downregulated BL: -1.940 Regeneration-depleted BL: -1.940 |
GSTP1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_003483 {REF} {Length: 1133} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=56.7]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=33.6]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=26.4]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=26.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=20.4]; Glutathione S-transferase N-terminal domain [PF17172.6, score=20.3]} {Human: ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=139, Expect=1e-40]} {Mouse: ENSMUSG00000097830, Gstp1, glutathione S-transferase, pi 1, [RH, Score=144, Expect=8e-43]; ENSMUSG00000060803, Gstp1, glutathione S-transferase, pi 1, [RH, Score=144, Expect=8e-43]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [RH, Score=99.8, Expect=2e-25]} {Celegans: WBGene00001749, gst-1, Glutathione S-transferase P, [RH, Score=147, Expect=1e-44]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=96.3, Expect=7e-25]} {RNA1509_37855, RNA1509_42842, RNA1509_53728, RNA1509_6171} {RNA1310_28502.1, RNA1509_37855, RNA1509_42842, RNA1509_53728, RNA1509_6171} {RNA1509_37855, RNA1509_42842, RNA1509_53728, RNA1509_6171, RNA815_13314} |
2. | MligTC455_26887 | 7607 | 158.47 | Mlig455_022436 | Neo: - Age: - Region-enriched R7: 5.346/0.00000 Regeneration-depleted BL: -6.390 |
1.845 | - | - | - | 0.893 | 0.952 | - | Mlig455_022436 {REF} {Length: 2812} {NoTransDecoderORF} {RNA1509_1460} {RNA1310_27964} {RNA815_19312} | |
3. | MligTC455_35188 | 340 | 7.08 | Mlig455_017705, Mlig455_017757 | Neo: - Age: - Region-enriched R7: 4.175/0.00000 |
PLEKHB1 | 1.804 | - | - | - | - | 0.955 | 0.849 | Mlig455_017705 {REF} {Length: 1121} {Pfam: PH domain [PF00169.31, score=38.5]} {Human: ENSG00000021300, PLEKHB1, pleckstrin homology domain containing B1, [RH, Score=76.6, Expect=1e-16]; ENSG00000115762, PLEKHB2, pleckstrin homology domain containing B2, [RH, Score=75.5, Expect=3e-16]} {Mouse: ENSMUSG00000030701, Plekhb1, pleckstrin homology domain containing, family B (evectins) member 1, [RH, Score=79.7, Expect=5e-18]; ENSMUSG00000026123, Plekhb2, pleckstrin homology domain containing, family B (evectins) member 2, [RH, Score=78.2, Expect=2e-17]} {Smed: dd_Smed_v6_1927_0_1, dd_Smed_v6_1927_0_1, [RH, Score=124, Expect=4e-35]} {RNA1509_56045} {RNA1310_40666.2} {RNA815_39297} Mlig455_017757 {REF} {Length: 1030} {Pfam: PH domain [PF00169.31, score=38.5]} {Human: ENSG00000021300, PLEKHB1, pleckstrin homology domain containing B1, [RH, Score=76.6, Expect=1e-16]; ENSG00000115762, PLEKHB2, pleckstrin homology domain containing B2, [RH, Score=75.5, Expect=3e-16]} {Mouse: ENSMUSG00000030701, Plekhb1, pleckstrin homology domain containing, family B (evectins) member 1, [RH, Score=79.7, Expect=5e-18]; ENSMUSG00000026123, Plekhb2, pleckstrin homology domain containing, family B (evectins) member 2, [RH, Score=78.2, Expect=2e-17]} {Smed: dd_Smed_v6_1927_0_1, dd_Smed_v6_1927_0_1, [RH, Score=124, Expect=4e-35]} {RNA1509_56045} {RNA1310_40666.2, RNA1509_56045} {RNA1509_56045, RNA815_39297} |
4. | MligTC455_44194 | 195 | 4.07 | Mlig455_049839, Mlig455_049886 | Neo: - Age: - |
1.718 | - | - | - | - | 0.959 | 0.759 | Mlig455_049839 {REF} {Length: 415} {RNA1509_2806, RNA1509_699} Mlig455_049886 {REF} {Length: 378} {NoTransDecoderORF} {RNA1509_2806, RNA1509_798} |
|
5. | MligTC455_49821 | 2230 | 46.46 | Mlig455_008776, Mlig455_008813 | Neo: - |
0.965 | - | - | - | - | 0.965 | - | Mlig455_008776 {REF} {Length: 834} {RNA1509_24401} {RNA1310_40742} {RNA815_19348} Mlig455_008813 {REF} {Length: 935} {RNA1509_24401, RNA1509_44113} {RNA1310_40742, RNA1509_24401, RNA1509_44113} {RNA1509_24401, RNA1509_44113, RNA815_19348} |
|
6. | MligTC455_01849 | 9 | 0.19 | Mlig455_047954 | Neo: - Age: - |
0.963 | - | - | - | - | 0.963 | - | Mlig455_047954 {REF} {Length: 100} {NoTransDecoderORF} {RNA1509_25809} {RNA1310_27224.2} {RNA815_4317.1} | |
7. | MligTC455_38673 | 821 | 17.11 | Mlig455_060661 | Neo: - Age: - |
MAP3K7 | 0.96 | - | - | - | - | 0.960 | - | Mlig455_060661 {REF} {Length: 997} {Pfam: Protein kinase domain [PF00069.27, score=81.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=74.5]} {Human: ENSG00000135341, MAP3K7, mitogen-activated protein kinase kinase kinase 7, [Score=89.0, Expect=1e-20]} {Mouse: ENSMUSG00000028284, Map3k7, mitogen-activated protein kinase kinase kinase 7, [Score=89.0, Expect=1e-20]} {Dmel: FBgn0030018, slpr, slipper, [Score=66.6, Expect=4e-13]} {Celegans: WBGene00006971, zak-1, Mammalian ZAK kinase homolog, [Score=66.2, Expect=5e-13]} {Smed: dd_Smed_v6_2822_0_20, dd_Smed_v6_2822_0_20, [Score=67.0, Expect=9e-14]} {RNA1509_6833} {RNA1310_9609} {RNA815_3249.1} |
8. | MligTC455_29665 | 3581 | 74.61 | Mlig455_032761 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-0.767 Region-enriched R7: 5.512/0.00000 Regeneration-downregulated BL: -12.313 Regeneration-depleted BL: -12.313 |
ADAMTS4 | 0.957 | - | - | - | - | 0.957 | - | Mlig455_032761 {REF} {Length: 1733} {TRANSSPLICED} {Pfam: Metallo-peptidase family M12 [PF13688.8, score=45.3]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=41.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=39.4]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=32.1]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=31.7]; ADAM cysteine-rich domain [PF17771.3, score=25.3]} {Human: ENSG00000158859, ADAMTS4, ADAM metallopeptidase with thrombospondin type 1 motif 4, [Score=69.3, Expect=9e-12]; ENSG00000166106, ADAMTS15, ADAM metallopeptidase with thrombospondin type 1 motif 15, [Score=68.9, Expect=1e-11]; ENSG00000154736, ADAMTS5, ADAM metallopeptidase with thrombospondin type 1 motif 5, [Score=68.2, Expect=2e-11]; ENSG00000154734, ADAMTS1, ADAM metallopeptidase with thrombospondin type 1 motif 1, [Score=68.2, Expect=2e-11]} {Mouse: ENSMUSG00000022894, Adamts5, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2), [Score=70.1, Expect=4e-12]; ENSMUSG00000006403, Adamts4, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, [Score=67.8, Expect=2e-11]; ENSMUSG00000033453, Adamts15, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15, [Score=67.4, Expect=2e-11]} {Dmel: FBgn0034903, sona, sol narae, [Score=68.6, Expect=8e-12]} {Celegans: WBGene00003248, mig-17, ADAM family mig-17, [Score=57.4, Expect=1e-08]} {RNA1509_3744, RNA1509_45506} {RNA1310_15616.1, RNA1509_3744, RNA1509_45506} {RNA1509_3744, RNA1509_45506, RNA815_5875.1} |
9. | MligTC455_47231 | 1055 | 21.97 | Mlig455_043583, Mlig455_043585, Mlig455_056791, Mlig455_056813 | Neo: - Age: Down-Up-Up Regeneration-upregulated TP: 3.106 Regeneration-enriched TP: 3.106 |
0.957 | - | - | - | - | 0.957 | - | Mlig455_043583 {REF} {Length: 769} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_13184.1} {RNA815_23732} Mlig455_043585 {REF} {Length: 768} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_13184.1} {RNA815_23732} Mlig455_056791 {REF} {Length: 677} {NoTransDecoderORF} {RNA1310_13184.1} {RNA815_23732} Mlig455_056813 {REF} {Length: 719} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_13184.1} {RNA815_23732} |
|
10. | MligTC455_07032 | 110 | 2.28 | Mlig455_008989, Mlig455_047374 | Neo: - Age: - |
KCNB2 | 0.955 | - | - | - | - | 0.955 | - | Mlig455_008989 {REF} {Length: 552} {RNA1310_61901} {RNA815_44232} Mlig455_047374 {REF} {Length: 1466} {Pfam: Ion transport protein [PF00520.33, score=72.8]; Ion channel [PF07885.18, score=57.2]} {Human: ENSG00000182674, KCNB2, potassium voltage-gated channel subfamily B member 2, [Score=118, Expect=2e-29]; ENSG00000158445, KCNB1, potassium voltage-gated channel subfamily B member 1, [Score=118, Expect=1e-29]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [Score=114, Expect=2e-28]} {Mouse: ENSMUSG00000050556, Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1, [Score=118, Expect=8e-30]; ENSMUSG00000092083, Kcnb2, potassium voltage gated channel, Shab-related subfamily, member 2, [Score=118, Expect=1e-29]} {Dmel: FBgn0262593, Shab, Shaker cognate b, [Score=118, Expect=7e-30]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=112, Expect=3e-28]} {Smed: dd_Smed_v6_25015_0_1, dd_Smed_v6_25015_0_1, [RH, Score=141, Expect=2e-41]} {RNA1509_26535} {RNA1310_9659.1} {RNA815_44232} |
11. | MligTC455_20933 | 21 | 0.43 | Mlig455_013811 | Neo: - Age: - |
0.954 | - | - | - | - | 0.954 | - | Mlig455_013811 {REF} {Length: 2349} {Pfam: Glycine rich protein [PF12810.9, score=43.4]; PAN domain [PF00024.28, score=21.7]} {RNA1310_61234} {RNA815_39176} | |
12. | MligTC455_21560 | 12198 | 254.13 | Mlig455_059034 | Neo: - Age: Down-Up-Up |
0.954 | - | - | - | - | 0.954 | - | Mlig455_059034 {REF} {Length: 1510} {Pfam: AIG1 family [PF04548.18, score=33.4]; 50S ribosome-binding GTPase [PF01926.25, score=33.2]; Dynamin family [PF00350.25, score=21.6]} {RNA1509_2495, RNA1509_4849, RNA1509_58949, RNA1509_6353, RNA1509_8870} {RNA1310_39963, RNA1509_2495, RNA1509_4849, RNA1509_58949, RNA1509_6353, RNA1509_8870} {RNA1509_2495, RNA1509_4849, RNA1509_58949, RNA1509_6353, RNA1509_8870, RNA815_18333} | |
13. | MligTC455_38672 | 1838 | 38.3 | Mlig455_025594, Mlig455_060614 | Neo: - Age: - |
MAP3K7 | 0.951 | - | - | - | - | 0.951 | - | Mlig455_025594 {REF} {Length: 3541} {Pfam: Protein kinase domain [PF00069.27, score=158.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=151.5]; Fungal protein kinase [PF17667.3, score=24.7]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=23.1]; MraW methylase family [PF01795.21, score=22.0]} {Human: ENSG00000135341, MAP3K7, mitogen-activated protein kinase kinase kinase 7, [Score=152, Expect=4e-39]} {Mouse: ENSMUSG00000028284, Map3k7, mitogen-activated protein kinase kinase kinase 7, [Score=152, Expect=4e-39]} {Dmel: FBgn0026323, Tak1, TGF-beta activated kinase 1, [Score=114, Expect=7e-26]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [Score=102, Expect=3e-22]} {Smed: dd_Smed_v6_953_0_1, dd_Smed_v6_953_0_1, [Score=129, Expect=2e-31]} {RNA1509_6833} {RNA1310_11206} {RNA815_3249.1} Mlig455_060614 {REF} {Length: 2473} {Pfam: Protein kinase domain [PF00069.27, score=158.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=152.1]; Fungal protein kinase [PF17667.3, score=25.2]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=23.1]; MraW methylase family [PF01795.21, score=22.6]} {Human: ENSG00000135341, MAP3K7, mitogen-activated protein kinase kinase kinase 7, [Score=154, Expect=5e-40]} {Mouse: ENSMUSG00000028284, Map3k7, mitogen-activated protein kinase kinase kinase 7, [Score=154, Expect=4e-40]} {Dmel: FBgn0026323, Tak1, TGF-beta activated kinase 1, [Score=115, Expect=1e-26]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [Score=104, Expect=5e-23]} {Smed: dd_Smed_v6_953_0_1, dd_Smed_v6_953_0_1, [Score=128, Expect=1e-31]} {RNA1509_47567, RNA1509_6833} {RNA1310_9609, RNA1509_47567} {RNA1509_47567, RNA815_3249.1} |
14. | MligTC455_18114 | 414 | 8.63 | Mlig455_038324, Mlig455_050230 | Neo: - Age: Down-Up-Down |
0.95 | - | - | - | - | 0.950 | - | Mlig455_038324 {REF} {Length: 2163} {Pfam: Transmembrane protein family 72 [PF16054.7, score=60.9]} {Smed: dd_Smed_v6_6789_0_1, dd_Smed_v6_6789_0_1, [RH, Score=94.7, Expect=4e-24]} {RNA1509_37575} {RNA1310_23999} {RNA815_9176.1} Mlig455_050230 {REF} {Length: 2326} {Pfam: Transmembrane protein family 72 [PF16054.7, score=60.9]} {Smed: dd_Smed_v6_6789_0_1, dd_Smed_v6_6789_0_1, [RH, Score=94.7, Expect=4e-24]} {RNA1509_37575} {RNA1310_23999, RNA1509_37575} {RNA1509_37575, RNA815_26984} |
|
15. | MligTC455_33838 | 11 | 0.22 | Mlig455_052207 | Neo: Irradiation Age: - |
DNMT3A | 0.95 | - | - | - | - | 0.950 | - | Mlig455_052207 {REF} {Length: 2753} {TRANSSPLICED} {Pfam: C-5 cytosine-specific DNA methylase [PF00145.19, score=68.8]; Cysteine rich ADD domain in DNMT3 [PF17980.3, score=33.3]} {Human: ENSG00000119772, DNMT3A, DNA methyltransferase 3 alpha, [RH, Score=324, Expect=1e-96]; ENSG00000088305, DNMT3B, DNA methyltransferase 3 beta, [RH, Score=320, Expect=9e-96]} {Mouse: ENSMUSG00000027478, Dnmt3b, DNA methyltransferase 3B, [RH, Score=337, Expect=2e-102]; ENSMUSG00000020661, Dnmt3a, DNA methyltransferase 3A, [RH, Score=324, Expect=6e-97]} {RNA1509_24795} {RNA1310_4717.1} {RNA815_27312} |