Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_39842 | 82 | 1.71 | Mlig455_061146 | Neo: - Age: - Regeneration-enriched R6: 11.621 |
WNT2B | Mlig455_061146 {REF} {Length: 1636} {Pfam: wnt family [PF00110.21, score=133.7]} {Human: ENSG00000134245, WNT2B, Wnt family member 2B, [Score=81.6, Expect=3e-16]; ENSG00000188064, WNT7B, Wnt family member 7B, [Score=80.1, Expect=6e-16]; ENSG00000002745, WNT16, Wnt family member 16, [Score=80.1, Expect=7e-16]; ENSG00000276799, WNT9B, Wnt family member 9B, [Score=79.0, Expect=2e-15]; ENSG00000158955, WNT9B, Wnt family member 9B, [Score=79.0, Expect=2e-15]; ENSG00000162552, WNT4, Wnt family member 4, [Score=77.8, Expect=4e-15]} {Mouse: ENSMUSG00000027840, Wnt2b, wingless-type MMTV integration site family, member 2B, [Score=80.1, Expect=6e-16]; ENSMUSG00000022382, Wnt7b, wingless-type MMTV integration site family, member 7B, [Score=78.6, Expect=1e-15]; ENSMUSG00000021994, Wnt5a, wingless-type MMTV integration site family, member 5A, [Score=77.8, Expect=3e-15]; ENSMUSG00000036856, Wnt4, wingless-type MMTV integration site family, member 4, [Score=77.8, Expect=3e-15]; ENSMUSG00000029671, Wnt16, wingless-type MMTV integration site family, member 16, [Score=77.4, Expect=4e-15]; ENSMUSG00000030093, Wnt7a, wingless-type MMTV integration site family, member 7A, [Score=76.6, Expect=6e-15]} {Dmel: FBgn0010453, Wnt4, Wnt oncogene analog 4, [Score=82.0, Expect=2e-16]} {Celegans: WBGene00000857, cwn-1, [Score=72.8, Expect=8e-14]} {Smed: dd_Smed_v6_14391_0_1, dd_Smed_v6_14391_0_1, [Score=117, Expect=6e-29]} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -2.436 | 1.66 | 0.99996 | 1.00000 | |
RegionR2 | 4.309 | 1.66 | 0.99989 | 1.00000 | |
RegionR3 | 0.229 | 1.66 | 0.99998 | 1.00000 | |
RegionR4 | -3.557 | 1.66 | 0.99975 | 1.00000 | |
RegionR5 | -1.461 | 1.66 | 0.99984 | 1.00000 | |
RegionR6 | 0.17 | 1.66 | 0.99998 | 1.00000 | |
RegionR7 | 1.105 | 1.66 | 0.99994 | 1.00000 | |
RegionR8 | 1.642 | 1.66 | 0.99993 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 7.398 | 1.66 | 0.99993 | 1.00000 | |
RegenerationR2 | 4.342 | 1.66 | 0.03222 | 0.29447 | |
RegenerationR3 | 8.435 | 1.66 | 0.00000 | 0.00007 | |
RegenerationR4 | 9.263 | 1.66 | 0.00000 | 0.00000 | |
RegenerationR5 | 10.486 | 1.66 | 0.00000 | 0.00000 | |
RegenerationR6 | 11.621 | 1.66 | 0.00000 | 0.00000 | |
RegenerationBL | 9.926 | 1.66 | 0.00000 | 0.00000 | |
RegenerationTP | 7.109 | 1.66 | 0.00344 | 0.09778 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_39842 | 82 | 1.71 | Mlig455_061146 | Neo: - Age: - Regeneration-enriched R6: 11.621 |
WNT2B | 3 | - | - | - | 1.000 | 1.000 | 1.000 | Mlig455_061146 {REF} {Length: 1636} {Pfam: wnt family [PF00110.21, score=133.7]} {Human: ENSG00000134245, WNT2B, Wnt family member 2B, [Score=81.6, Expect=3e-16]; ENSG00000188064, WNT7B, Wnt family member 7B, [Score=80.1, Expect=6e-16]; ENSG00000002745, WNT16, Wnt family member 16, [Score=80.1, Expect=7e-16]; ENSG00000276799, WNT9B, Wnt family member 9B, [Score=79.0, Expect=2e-15]; ENSG00000158955, WNT9B, Wnt family member 9B, [Score=79.0, Expect=2e-15]; ENSG00000162552, WNT4, Wnt family member 4, [Score=77.8, Expect=4e-15]} {Mouse: ENSMUSG00000027840, Wnt2b, wingless-type MMTV integration site family, member 2B, [Score=80.1, Expect=6e-16]; ENSMUSG00000022382, Wnt7b, wingless-type MMTV integration site family, member 7B, [Score=78.6, Expect=1e-15]; ENSMUSG00000021994, Wnt5a, wingless-type MMTV integration site family, member 5A, [Score=77.8, Expect=3e-15]; ENSMUSG00000036856, Wnt4, wingless-type MMTV integration site family, member 4, [Score=77.8, Expect=3e-15]; ENSMUSG00000029671, Wnt16, wingless-type MMTV integration site family, member 16, [Score=77.4, Expect=4e-15]; ENSMUSG00000030093, Wnt7a, wingless-type MMTV integration site family, member 7A, [Score=76.6, Expect=6e-15]} {Dmel: FBgn0010453, Wnt4, Wnt oncogene analog 4, [Score=82.0, Expect=2e-16]} {Celegans: WBGene00000857, cwn-1, [Score=72.8, Expect=8e-14]} {Smed: dd_Smed_v6_14391_0_1, dd_Smed_v6_14391_0_1, [Score=117, Expect=6e-29]} |
2. | MligTC455_47530 | 800 | 16.67 | Mlig455_006029 | Neo: - Age: - Region-enriched R6: 4.749/0.00000 |
WNT9B | 2.633 | - | - | - | 0.900 | 0.982 | 0.751 | Mlig455_006029 {REF} {Length: 2805} {Pfam: wnt family [PF00110.21, score=133.2]} {Human: ENSG00000158955, WNT9B, Wnt family member 9B, [Score=86.7, Expect=6e-18]; ENSG00000276799, WNT9B, Wnt family member 9B, [Score=86.7, Expect=6e-18]} {Mouse: ENSMUSG00000015957, Wnt11, wingless-type MMTV integration site family, member 11, [Score=86.7, Expect=4e-18]; ENSMUSG00000029671, Wnt16, wingless-type MMTV integration site family, member 16, [Score=84.7, Expect=2e-17]} {Celegans: WBGene00000857, cwn-1, [Score=87.8, Expect=1e-18]} {Smed: dd_Smed_v6_14391_0_1, dd_Smed_v6_14391_0_1, [Score=134, Expect=9e-35]} {RNA1509_18165} {RNA1310_9195.1, RNA1509_18165} {RNA1509_18165, RNA815_10665} |
3. | MligTC455_25861 | 1578 | 32.88 | Mlig455_028673 | Neo: - Age: - Region-enriched R6: 2.474/0.00013 |
GLIPR2 | 1.826 | - | - | - | - | 0.957 | 0.869 | Mlig455_028673 {REF} {Length: 2280} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=85.0]} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [Score=106, Expect=2e-27]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [Score=108, Expect=2e-28]} {Dmel: FBgn0051482, CG31482, [Score=101, Expect=3e-25]} {Celegans: WBGene00017055, D2062.1, [Score=74.3, Expect=2e-15]} {Smed: dd_Smed_v6_762_0_2, dd_Smed_v6_762_0_2, [RH, Score=149, Expect=6e-43]} {RNA1509_26273, RNA1509_5334} {RNA1310_33115, RNA1509_26273} {RNA1509_26273, RNA815_15217.1} |
4. | MligTC455_14377 | 210 | 4.37 | Mlig455_022946, Mlig455_046360, Mlig455_046393 | Neo: - Age: logFC(26M/2M)=-0.362 Region-enriched R6: 6.942/0.00000 |
1.825 | - | - | - | - | 0.981 | 0.844 | Mlig455_022946 {REF} {Length: 170} {NoTransDecoderORF} {tRNA: Arg(ACG), score=72.3} {RNA1509_29923} {RNA1310_14861.1} {RNA815_5114} Mlig455_046360 {REF} {Length: 1953} {tRNA: Arg(ACG), score=72.3} {RNA1509_29923} {RNA1310_13935.1} {RNA815_5114} Mlig455_046393 {REF} {Length: 1824} {tRNA: Arg(ACG), score=72.3} {RNA1509_29923} {RNA1310_14861.1} {RNA815_5114} |
|
5. | MligTC455_22850 | 372 | 7.75 | Mlig455_031130 | Neo: - Age: Down-Up-Up Region-enriched R7: 3.011/0.00131 Regeneration-enriched R5: 2.202 |
1.789 | - | - | - | 0.834 | 0.955 | - | Mlig455_031130 {REF} {Length: 3011} {Smed: dd_Smed_v6_7191_0_1, dd_Smed_v6_7191_0_1, [RH, Score=116, Expect=3e-28]} {RNA1509_36152} {RNA1310_7995, RNA1509_36152} {RNA1509_36152, RNA815_32401} | |
6. | MligTC455_09184 | 172 | 3.59 | Mlig455_049490 | Neo: - Age: Up-Down-Up Region-enriched R6: 2.250/0.01050 |
FZD10 | 1.759 | - | - | - | 0.789 | - | 0.970 | Mlig455_049490 {REF} {Length: 3141} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=284.4]; Fz domain [PF01392.24, score=71.1]} {Human: ENSG00000111432, FZD10, frizzled class receptor 10, [Score=304, Expect=2e-94]; ENSG00000163251, FZD5, frizzled class receptor 5, [Score=294, Expect=1e-90]; ENSG00000188763, FZD9, frizzled class receptor 9, [Score=290, Expect=3e-89]} {Mouse: ENSMUSG00000049551, Fzd9, frizzled class receptor 9, [Score=308, Expect=3e-96]; ENSMUSG00000081683, Fzd10, frizzled class receptor 10, [Score=301, Expect=2e-93]; ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [Score=295, Expect=3e-91]} {Dmel: FBgn0001085, fz, frizzled, [Score=231, Expect=1e-67]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=238, Expect=5e-70]} {Smed: dd_Smed_v6_11650_0_1, dd_Smed_v6_11650_0_1, [Score=294, Expect=2e-90]} {RNA1509_26552} {RNA1310_10390, RNA1509_26552} {RNA1509_26552, RNA815_21631} |
7. | MligTC455_21395 | 60 | 1.25 | Mlig455_048524 | Neo: - Age: - |
1.748 | - | - | - | - | 0.798 | 0.950 | Mlig455_048524 {REF} {Length: 2046} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=27.3]} {RNA1310_102808} {RNA815_55644} | |
8. | MligTC455_40222 | 35 | 0.74 | Mlig455_030505 | Neo: - Age: - |
RABL6 | 1.742 | - | - | - | 0.791 | 0.951 | - | Mlig455_030505 {REF} {Length: 1394} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=50.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=27.6]} {Human: ENSG00000196642, RABL6, RAB, member RAS oncogene family like 6, [Score=189, Expect=6e-55]} {Mouse: ENSMUSG00000015087, Rabl6, RAB, member RAS oncogene family-like 6, [Score=170, Expect=1e-46]} {Dmel: FBgn0015790, Rab11, [Score=57.0, Expect=3e-09]} {Celegans: WBGene00008585, F08G12.1, [Score=162, Expect=2e-44]} {Smed: dd_Smed_v6_6925_0_3, dd_Smed_v6_6925_0_3, [Score=205, Expect=3e-63]} {RNA1509_14391} {RNA1310_3744.1} {RNA815_23301} |
9. | MligTC455_33793 | 8807 | 183.49 | Mlig455_019483, Mlig455_066893 | Neo: - Age: logFC(26M/2M)=0.194 Region-specific R6: 2.135 Region-enriched R6: 2.053/0.00000 |
PDIA5 | 1.719 | - | - | - | 0.751 | 0.968 | - | Mlig455_019483 {REF} {Length: 2162} {Pfam: Thioredoxin [PF00085.22, score=218.3]; AhpC/TSA family [PF00578.23, score=67.5]; Thioredoxin-like domain [PF13098.8, score=62.9]; Thioredoxin-like [PF13905.8, score=58.0]; Redoxin [PF08534.12, score=50.8]; Thioredoxin-like [PF13899.8, score=50.7]; OST3 / OST6 family, transporter family [PF04756.15, score=35.3]; ERp29, N-terminal domain [PF07912.15, score=31.0]; Eukaryotic protein of unknown function (DUF953) [PF06110.13, score=29.8]; Thioredoxin [PF14595.8, score=27.3]; Glutaredoxin [PF00462.26, score=26.6]; DSBA-like thioredoxin domain [PF01323.22, score=20.8]; Thioredoxin domain [PF13192.8, score=20.5]} {Human: ENSG00000065485, PDIA5, protein disulfide isomerase family A member 5, [Score=162, Expect=4e-44]} {Mouse: ENSMUSG00000022844, Pdia5, protein disulfide isomerase associated 5, [Score=162, Expect=2e-44]} {Dmel: FBgn0032514, CG9302, [Score=181, Expect=1e-51]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=113, Expect=2e-27]} {Smed: dd_Smed_v6_821_0_1, dd_Smed_v6_821_0_1, [RH, Score=301, Expect=6e-99]} {RNA1509_920} {RNA1310_9004, RNA1509_920} {RNA1509_920, RNA815_4342} Mlig455_066893 {REF} {Length: 2056} {Pfam: Thioredoxin [PF00085.22, score=218.8]; AhpC/TSA family [PF00578.23, score=67.4]; Thioredoxin-like domain [PF13098.8, score=61.9]; Thioredoxin-like [PF13905.8, score=59.5]; Redoxin [PF08534.12, score=51.2]; Thioredoxin-like [PF13899.8, score=50.2]; OST3 / OST6 family, transporter family [PF04756.15, score=34.7]; Eukaryotic protein of unknown function (DUF953) [PF06110.13, score=29.8]; ERp29, N-terminal domain [PF07912.15, score=28.4]; Glutaredoxin [PF00462.26, score=27.9]; Thioredoxin [PF14595.8, score=27.0]; DSBA-like thioredoxin domain [PF01323.22, score=20.7]; Thioredoxin domain [PF13192.8, score=20.2]; F plasmid transfer operon protein [PF13728.8, score=18.5]} {Human: ENSG00000065485, PDIA5, protein disulfide isomerase family A member 5, [Score=164, Expect=6e-45]} {Mouse: ENSMUSG00000022844, Pdia5, protein disulfide isomerase associated 5, [Score=164, Expect=3e-45]} {Dmel: FBgn0032514, CG9302, [Score=183, Expect=3e-52]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_821_0_1, dd_Smed_v6_821_0_1, [RH, Score=303, Expect=1e-99]} {RNA1509_10941, RNA1509_37195, RNA1509_920} {RNA1310_9004, RNA1509_10941, RNA1509_37195} {RNA1509_10941, RNA1509_37195, RNA815_4342} |
10. | MligTC455_48335 | 529 | 11.02 | Mlig455_059727 | Neo: Int S/G2/M Age: - |
STT3A | 1.717 | - | - | - | - | 0.748 | 0.969 | Mlig455_059727 {REF} {Length: 3414} {TRANSSPLICED} {Pfam: Oligosaccharyl transferase STT3 subunit [PF02516.16, score=490.4]; Dolichyl-phosphate-mannose-protein mannosyltransferase [PF13231.8, score=24.3]} {Human: ENSG00000134910, STT3A, STT3A, catalytic subunit of the oligosaccharyltransferase complex, [RH, Score=1080, Expect=0.0]} {Mouse: ENSMUSG00000032116, Stt3a, STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae), [RH, Score=1077, Expect=0.0]} {Dmel: FBgn0031149, Stt3A, Catalytic subunit 3A of the oligosaccharyltransferase complex, [RH, Score=1066, Expect=0.0]} {Celegans: WBGene00020437, stt-3, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt-3, [Score=841, Expect=0.0]} {Smed: dd_Smed_v6_1174_0_1, dd_Smed_v6_1174_0_1, [RH, Score=1102, Expect=0.0]} {RNA1509_7265} {RNA1310_3970, RNA1509_7265} {RNA1509_7265, RNA815_3344} |
11. | MligTC455_33792 | 4453 | 92.77 | Mlig455_060544 | Neo: - Age: - Region-specific R6: 2.114 Region-enriched R6: 2.011/0.00000 |
PDIA5 | 1.7 | - | - | - | 0.730 | 0.970 | - | Mlig455_060544 {REF} {Length: 2158} {Pfam: Thioredoxin [PF00085.22, score=218.3]; AhpC/TSA family [PF00578.23, score=67.5]; Thioredoxin-like domain [PF13098.8, score=62.9]; Thioredoxin-like [PF13905.8, score=58.0]; Redoxin [PF08534.12, score=50.8]; Thioredoxin-like [PF13899.8, score=50.7]; OST3 / OST6 family, transporter family [PF04756.15, score=35.3]; ERp29, N-terminal domain [PF07912.15, score=31.0]; Eukaryotic protein of unknown function (DUF953) [PF06110.13, score=29.8]; Thioredoxin [PF14595.8, score=27.2]; Glutaredoxin [PF00462.26, score=26.6]; DSBA-like thioredoxin domain [PF01323.22, score=20.8]; Thioredoxin domain [PF13192.8, score=20.5]} {Human: ENSG00000065485, PDIA5, protein disulfide isomerase family A member 5, [Score=163, Expect=1e-44]} {Mouse: ENSMUSG00000022844, Pdia5, protein disulfide isomerase associated 5, [Score=164, Expect=6e-45]} {Dmel: FBgn0032514, CG9302, [Score=179, Expect=7e-51]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_821_0_1, dd_Smed_v6_821_0_1, [RH, Score=302, Expect=4e-99]} {RNA1509_19968, RNA1509_52294, RNA1509_920} {RNA1310_9004, RNA1509_19968, RNA1509_52294} {RNA1509_19968, RNA1509_52294, RNA815_4342} |
12. | MligTC455_21566 | 120 | 2.51 | Mlig455_059038, Mlig455_070844 | Neo: - |
GIMAP7 | 1.693 | - | - | - | 0.957 | 0.736 | - | Mlig455_059038 {REF} {Length: 1740} {Pfam: AIG1 family [PF04548.18, score=133.6]; 50S ribosome-binding GTPase [PF01926.25, score=34.0]; Dynamin family [PF00350.25, score=24.4]; Septin [PF00735.20, score=22.0]; ABC transporter [PF00005.29, score=21.4]; Ferrous iron transport protein B [PF02421.20, score=18.3]} {Human: ENSG00000179144, GIMAP7, GTPase, IMAP family member 7, [Score=88.2, Expect=2e-19]} {Mouse: ENSMUSG00000043931, Gimap7, GTPase, IMAP family member 7, [RH, Score=94.4, Expect=9e-22]} {RNA1509_14293} {RNA1310_21879.1} {RNA815_8194.1} Mlig455_070844 {REF} {Length: 1755} {Pfam: AIG1 family [PF04548.18, score=138.3]; 50S ribosome-binding GTPase [PF01926.25, score=35.2]; Dynamin family [PF00350.25, score=24.9]; Septin [PF00735.20, score=20.5]} {Human: ENSG00000179144, GIMAP7, GTPase, IMAP family member 7, [Score=92.8, Expect=6e-21]} {Mouse: ENSMUSG00000043931, Gimap7, GTPase, IMAP family member 7, [RH, Score=99.4, Expect=2e-23]} {RNA1509_14293} {RNA1310_21879.1} {RNA815_8194.1} |
13. | MligTC455_40176 | 48 | 1.01 | Mlig455_062901 | Neo: - Age: Down-Up-Down Region-enriched R3: 4.455/0.04678 |
DMRT2 | 0.965 | - | - | - | - | - | 0.965 | Mlig455_062901 {REF} {Length: 1531} {Pfam: DM DNA binding domain [PF00751.20, score=75.0]} {Human: ENSG00000173253, DMRT2, doublesex and mab-3 related transcription factor 2, [RH, Score=122, Expect=4e-31]} {Mouse: ENSMUSG00000048138, Dmrt2, doublesex and mab-3 related transcription factor 2, [RH, Score=123, Expect=2e-31]} {Dmel: FBgn0030477, dmrt11E, doublesex-Mab related 11E, [RH, Score=120, Expect=1e-31]} {Celegans: WBGene00017326, dmd-5, DM (Doublesex/MAB-3) Domain family, [Score=100, Expect=7e-25]} {Smed: dd_Smed_v6_13283_0_1, dd_Smed_v6_13283_0_1, [RH, Score=115, Expect=1e-30]} {RNA1509_30715} {RNA1310_35922} {RNA815_9171.1} |
14. | MligTC455_11736 | 19 | 0.39 | Mlig455_031660 | Neo: - Age: - |
0.955 | - | - | - | 0.955 | - | - | Mlig455_031660 {REF} {Length: 680} {RNA1310_76333} {RNA815_54433} |