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Results for MligTC455_40349

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_40349 84 1.74 Mlig455_050726

Neo: -

Age: Down-Up-Up

Mlig455_050726 {REF} {Length: 2409} {Pfam: NHL repeat [PF01436.23, score=32.4]} {RNA1509_56255} {RNA1310_46961} {RNA815_45776}

Cumulative graph for MligTC455_40349

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -3.586 1.876 0.99966 1.00000
RegionR2 1.203 1.876 0.34177 0.73404
RegionR3 0.814 1.876 0.46685 0.97368
RegionR4 2.052 1.876 0.10150 0.31043
RegionR5 1.213 1.876 0.27797 0.60513
RegionR6 1.106 1.876 0.34690 0.93257
RegionR7 1.186 1.876 0.39221 1.00000
RegionR8 -3.988 1.876 1.00000 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.707 1.876 1.00000 1.00000
RegenerationR2 -0.174 1.876 0.77754 0.98268
RegenerationR3 -0.417 1.876 0.61248 0.91379
RegenerationR4 -0.504 1.876 0.54270 0.88957
RegenerationR5 -0.535 1.876 0.47325 0.84343
RegenerationR6 -0.555 1.876 0.50555 0.81036
RegenerationBL 0.587 1.876 0.65226 0.98884
RegenerationTP 0.993 1.876 0.61271 0.96800


Genes with expression patterns similar to MligTC455_40349

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_40349 84 1.74 Mlig455_050726

Neo: -

Age: Down-Up-Up

5 - 1.000 1.000 1.000 1.000 1.000 Mlig455_050726 {REF} {Length: 2409} {Pfam: NHL repeat [PF01436.23, score=32.4]} {RNA1509_56255} {RNA1310_46961} {RNA815_45776}
2. MligTC455_36853 202 4.21 Mlig455_043548

Neo: -

Age: -

CCDC191 0.973 - - - - 0.973 - Mlig455_043548 {REF} {Length: 4123} {TRANSSPLICED} {Human: ENSG00000163617, CCDC191, coiled-coil domain containing 191, [Score=115, Expect=1e-25]} {Mouse: ENSMUSG00000022701, Ccdc191, coiled-coil domain containing 191, [RH, Score=95.9, Expect=1e-19]} {Dmel: FBgn0031496, CG17258, [RH, Score=56.2, Expect=1e-07]} {Smed: dd_Smed_v6_8967_0_2, dd_Smed_v6_8967_0_2, [Score=136, Expect=1e-32]} {RNA1509_15334, RNA1509_39248} {RNA1310_1501.1, RNA1509_15334} {RNA1509_15334, RNA815_1513}
3. MligTC455_42659 2799 58.31 Mlig455_009046, Mlig455_058134

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.179

PACSIN2 0.966 - - - - 0.966 -

Mlig455_009046 {REF} {Length: 3055} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=54.6]; SH3 domain [PF00018.30, score=51.8]; Fes/CIP4, and EFC/F-BAR homology domain [PF00611.25, score=51.0]; Variant SH3 domain [PF07653.19, score=34.2]} {Human: ENSG00000100266, PACSIN2, protein kinase C and casein kinase substrate in neurons 2, [Score=325, Expect=5e-105]} {Mouse: ENSMUSG00000016664, Pacsin2, protein kinase C and casein kinase substrate in neurons 2, [RH, Score=335, Expect=2e-109]} {Dmel: FBgn0053094, Synd, Syndapin, [Score=285, Expect=4e-90]} {Celegans: WBGene00018467, sdpn-1, SynDaPiN (Synaptic dynamin binding protein) homolog, [Score=219, Expect=6e-65]} {Smed: dd_Smed_v6_7987_0_1, dd_Smed_v6_7987_0_1, [Score=351, Expect=1e-115]} {RNA1509_22117, RNA1509_37584} {RNA1310_9530, RNA1509_22117} {RNA1509_22117, RNA815_8193}

Mlig455_058134 {REF} {Length: 3083} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=54.5]; SH3 domain [PF00018.30, score=51.7]; Fes/CIP4, and EFC/F-BAR homology domain [PF00611.25, score=50.9]; Variant SH3 domain [PF07653.19, score=34.1]} {Human: ENSG00000100266, PACSIN2, protein kinase C and casein kinase substrate in neurons 2, [Score=322, Expect=1e-103]} {Mouse: ENSMUSG00000016664, Pacsin2, protein kinase C and casein kinase substrate in neurons 2, [Score=329, Expect=9e-107]} {Dmel: FBgn0053094, Synd, Syndapin, [Score=286, Expect=5e-90]} {Celegans: WBGene00018467, sdpn-1, SynDaPiN (Synaptic dynamin binding protein) homolog, [Score=187, Expect=7e-53]} {Smed: dd_Smed_v6_7987_0_1, dd_Smed_v6_7987_0_1, [Score=337, Expect=4e-110]} {RNA1509_37584} {RNA1310_9122.1} {RNA815_8193}
4. MligTC455_12934 47 0.98 Mlig455_024068, Mlig455_055880

Neo: -

Age: -

0.965 - - - - 0.965 -

Mlig455_024068 {REF} {Length: 326} {NoTransDecoderORF} {RNA1310_135185} {RNA815_34264}

Mlig455_055880 {REF} {Length: 326} {NoTransDecoderORF} {RNA1310_135185} {RNA815_34264}
5. MligTC455_29780 59 1.23 Mlig455_039027

Neo: -

Age: -

MAP3K4 0.965 - - - - 0.965 - Mlig455_039027 {REF} {Length: 2075} {Pfam: Protein kinase domain [PF00069.27, score=161.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.8]; Ankyrin repeats (many copies) [PF13637.8, score=67.1]; Ankyrin repeats (3 copies) [PF12796.9, score=58.2]; Ankyrin repeats (many copies) [PF13857.8, score=55.5]; Ankyrin repeat [PF13606.8, score=30.8]; Fungal protein kinase [PF17667.3, score=24.7]; ABC1 atypical kinase-like domain [PF03109.18, score=21.9]; Ankyrin repeat [PF00023.32, score=21.7]; Kinase-like [PF14531.8, score=19.7]; Phosphotransferase enzyme family [PF01636.25, score=19.2]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=133, Expect=8e-32]} {Mouse: ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=2e-30]} {Dmel: FBgn0024329, Mekk1, [Score=124, Expect=2e-29]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=133, Expect=3e-32]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=111, Expect=2e-25]} {RNA1509_33450, RNA1509_51789} {RNA1310_32013, RNA1509_33450, RNA1509_51789} {RNA1509_33450, RNA1509_51789, RNA815_6977.1}
6. MligTC455_46858 43 0.89 Mlig455_027443

Neo: -

Age: Up-Down-Up

TJP1 0.965 - - - - 0.965 - Mlig455_027443 {REF} {Length: 3643} {Pfam: PDZ domain [PF00595.26, score=44.0]; PDZ domain [PF17820.3, score=28.6]; ZU5 domain [PF00791.22, score=27.8]; Guanylate kinase [PF00625.23, score=22.9]; PDZ domain [PF13180.8, score=20.5]} {Human: ENSG00000104067, TJP1, tight junction protein 1, [Score=165, Expect=7e-42]; ENSG00000277401, TJP1, tight junction protein 1, [Score=165, Expect=7e-42]; ENSG00000119139, TJP2, tight junction protein 2, [Score=157, Expect=3e-40]} {Mouse: ENSMUSG00000030516, Tjp1, tight junction protein 1, [Score=167, Expect=1e-42]} {Dmel: FBgn0262614, pyd, polychaetoid, [Score=184, Expect=3e-48]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=157, Expect=1e-39]} {Smed: dd_Smed_v6_7374_0_1, dd_Smed_v6_7374_0_1, [Score=51.2, Expect=2e-06]} {RNA1509_35829} {RNA1310_1784} {RNA815_1919}
7. MligTC455_09645 4 0.09 Mlig455_049831

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_049831 {REF} {Length: 357} {NoTransDecoderORF} {RNA1509_16732} {RNA1310_7776} {RNA815_5850}
8. MligTC455_33630 343 7.15 Mlig455_011677

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_011677 {REF} {Length: 1852} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_55678} {RNA1310_39931.1} {RNA815_24394.1}
9. MligTC455_47369 483 10.06 Mlig455_060339

Neo: -

Age: -

ELMOD2 0.959 - - - 0.959 - - Mlig455_060339 {REF} {Length: 1486} {TRANSSPLICED} {Pfam: ELMO/CED-12 family [PF04727.15, score=141.5]} {Human: ENSG00000179387, ELMOD2, ELMO domain containing 2, [RH, Score=182, Expect=5e-55]; ENSG00000110675, ELMOD1, ELMO domain containing 1, [RH, Score=181, Expect=3e-54]} {Mouse: ENSMUSG00000041986, Elmod1, ELMO/CED-12 domain containing 1, [RH, Score=178, Expect=3e-53]; ENSMUSG00000035151, Elmod2, ELMO/CED-12 domain containing 2, [RH, Score=177, Expect=2e-53]} {Dmel: FBgn0037473, CG10068, [RH, Score=202, Expect=5e-63]} {Celegans: WBGene00008348, C56G7.3, ELMO domain-containing protein C56G7.3, [Score=60.8, Expect=2e-10]} {Smed: dd_Smed_v6_7912_0_1, dd_Smed_v6_7912_0_1, [RH, Score=126, Expect=3e-34]} {RNA1509_28566, RNA1509_46206, RNA1509_49027} {RNA1310_23359, RNA1509_28566, RNA1509_46206, RNA1509_49027} {RNA1509_28566, RNA1509_46206, RNA1509_49027, RNA815_16549}
10. MligTC455_32642 14 0.28 Mlig455_026288

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_026288 {REF} {Length: 962} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=52.4, Expect=4e-09]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}
11. MligTC455_32643 14 0.28 Mlig455_043702

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_043702 {REF} {Length: 970} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=64.7, Expect=1e-12]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}
12. MligTC455_03503 75 1.57 Mlig455_042645

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.368

0.957 - - - - 0.957 - Mlig455_042645 {REF} {Length: 2491} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=36.7]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=77.8, Expect=2e-15]} {RNA1509_19205, RNA1509_53675} {RNA1310_10802.1, RNA1509_19205, RNA1509_53675} {RNA1509_19205, RNA1509_53675, RNA815_4389.1}
13. MligTC455_15048 4 0.08 Mlig455_039478

Neo: -

Age: -

ANK1 0.957 - - - - 0.957 - Mlig455_039478 {REF} {Length: 1232} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=71.1]; Ankyrin repeats (many copies) [PF13637.8, score=61.5]; Ankyrin repeat [PF00023.32, score=56.2]; Ankyrin repeats (many copies) [PF13857.8, score=54.4]; Ankyrin repeat [PF13606.8, score=45.5]; SAP domain [PF02037.29, score=25.5]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=55.1, Expect=5e-08]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=57.0, Expect=7e-09]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=50.4, Expect=9e-07]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=47.8, Expect=5e-06]} {Smed: dd_Smed_v6_2072_0_21, dd_Smed_v6_2072_0_21, [Score=49.7, Expect=8e-07]} {RNA1509_46740} {RNA1310_6951.1} {RNA815_11882}
14. MligTC455_19157 152 3.17 Mlig455_055906

Neo: -

Age: logFC(26M/2M)=0.764

Region-enriched R2: 2.840/0.03703

NUDT2 0.956 - - - - 0.956 - Mlig455_055906 {REF} {Length: 811} {TRANSSPLICED} {Pfam: NUDIX domain [PF00293.30, score=59.6]} {Human: ENSG00000164978, NUDT2, nudix hydrolase 2, [Score=72.8, Expect=2e-16]} {Mouse: ENSMUSG00000028443, Nudt2, nudix (nucleoside diphosphate linked moiety X)-type motif 2, [Score=71.2, Expect=5e-16]} {Dmel: FBgn0051713, Apf, diadenosine tetraphosphate hydrolase, [Score=71.2, Expect=3e-16]} {Celegans: WBGene00003581, ndx-4, Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], [Score=72.8, Expect=6e-17]} {RNA1509_22785} {RNA1310_44511} {RNA815_33249}
15. MligTC455_08530 63 1.3 Mlig455_020169

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_020169 {REF} {Length: 578} {RNA1509_31892} {RNA1310_66450} {RNA815_32511}
16. MligTC455_35008 283 5.89 Mlig455_067943

Neo: -

Age: -

MAPK7 0.954 - - - - 0.954 - Mlig455_067943 {REF} {Length: 4027} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=208.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.1]} {Human: ENSG00000166484, MAPK7, mitogen-activated protein kinase 7, [RH, Score=345, Expect=2e-106]} {Mouse: ENSMUSG00000001034, Mapk7, mitogen-activated protein kinase 7, [RH, Score=343, Expect=4e-106]} {Dmel: FBgn0003256, rl, rolled, [Score=278, Expect=1e-86]} {Celegans: WBGene00003402, mpk-2, Mitogen-activated protein kinase, [RH, Score=321, Expect=3e-102]} {Smed: dd_Smed_v6_4300_0_1, dd_Smed_v6_4300_0_1, [RH, Score=314, Expect=4e-97]} {RNA1509_27430, RNA1509_51899} {RNA1310_6095.1, RNA1509_27430, RNA1509_51899} {RNA1509_27430, RNA1509_51899, RNA815_12423}
17. MligTC455_36004 270 5.62 Mlig455_026689

Neo: -

Age: Up-Down-Down

DNAH14 0.954 - - - - 0.954 - Mlig455_026689 {REF} {Length: 15335} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=478.8]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=413.2]; P-loop containing dynein motor region D4 [PF12780.9, score=291.1]; Dynein heavy chain C-terminal domain [PF18199.3, score=250.1]; ATP-binding dynein motor region [PF12781.9, score=229.2]; P-loop containing dynein motor region [PF12775.9, score=203.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=125.1]; Dynein heavy chain AAA lid domain [PF18198.3, score=122.1]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=113.2]; Dynein heavy chain AAA lid domain [PF17852.3, score=84.3]; AAA ATPase domain [PF13191.8, score=52.0]; AAA domain (dynein-related subfamily) [PF07728.16, score=51.6]; AAA domain [PF13401.8, score=48.7]; AAA+ lid domain [PF17857.3, score=46.7]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=45.8]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=24.3]; AAA domain [PF13238.8, score=22.5]; NACHT domain [PF05729.14, score=20.6]; AAA domain [PF13671.8, score=20.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.6]; Protein of unknown function (DUF815) [PF05673.15, score=17.7]} {Human: ENSG00000185842, DNAH14, dynein axonemal heavy chain 14, [RH, Score=1709, Expect=0.0]} {Mouse: ENSMUSG00000052861, Dnah6, dynein, axonemal, heavy chain 6, [Score=1547, Expect=0.0]} {Dmel: FBgn0283476, Dhc16F, Dynein heavy chain at 16F, [Score=1206, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=617, Expect=6e-177]} {Smed: dd_Smed_v6_10969_0_1, dd_Smed_v6_10969_0_1, [RH, Score=2929, Expect=0.0]} {RNA1509_3937} {RNA1310_38.1} {RNA815_142}
18. MligTC455_45509 24 0.51 Mlig455_055497

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.555

PITPNM1 0.954 - - - - 0.954 - Mlig455_055497 {REF} {Length: 4896} {TRANSSPLICED} {Pfam: Phosphatidylinositol transfer protein [PF02121.20, score=344.9]; DDHD domain [PF02862.19, score=121.3]} {Human: ENSG00000110697, PITPNM1, phosphatidylinositol transfer protein membrane associated 1, [Score=464, Expect=4e-142]} {Mouse: ENSMUSG00000024851, Pitpnm1, phosphatidylinositol transfer protein, membrane-associated 1, [Score=468, Expect=6e-144]; ENSMUSG00000097096, Pitpnm1, phosphatidylinositol transfer protein, membrane-associated 1, [Score=468, Expect=6e-144]} {Dmel: FBgn0003218, rdgB, retinal degeneration B, [Score=398, Expect=2e-118]} {Celegans: WBGene00010813, pitp-1, PhosphatidylInositol Transfer Protein family, [RH, Score=358, Expect=8e-106]} {Smed: dd_Smed_v6_7211_0_1, dd_Smed_v6_7211_0_1, [Score=769, Expect=0.0]} {RNA1509_24836} {RNA1310_4306} {RNA815_17070}
19. MligTC455_52543 184 3.83 Mlig455_034643, Mlig455_062632

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.879/0.00387

0.954 - - - - 0.954 -

Mlig455_034643 {REF} {Length: 690} {Pfam: Dickkopf N-terminal cysteine-rich region [PF04706.14, score=19.5]} {RNA1310_10592.1} {RNA815_59658}

Mlig455_062632 {REF} {Length: 685} {Pfam: Dickkopf N-terminal cysteine-rich region [PF04706.14, score=19.5]} {RNA1310_10592.1} {RNA815_59658}
20. MligTC455_06229 40 0.84 Mlig455_033335

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_033335 {REF} {Length: 417} {RNA1310_7406.2} {RNA815_27098.2}
21. MligTC455_22804 350 7.3 Mlig455_067193

Neo: -

Age: logFC(26M/2M)=-0.439

Region-enriched R2: 2.883/0.00412

TEKT3 0.953 - - - - 0.953 - Mlig455_067193 {REF} {Length: 4067} {Pfam: Tektin family [PF03148.16, score=437.3]; fzo-like conserved region [PF04799.15, score=18.2]} {Human: ENSG00000125409, TEKT3, tektin 3, [Score=358, Expect=6e-119]} {Mouse: ENSMUSG00000042189, Tekt3, tektin 3, [Score=342, Expect=6e-113]} {Dmel: FBgn0052820, CG32820, [Score=286, Expect=5e-91]} {Smed: dd_Smed_v6_6511_0_1, dd_Smed_v6_6511_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_7137} {RNA1310_13532} {RNA815_5924}
22. MligTC455_28472 95 1.99 Mlig455_027357

Neo: -

Age: -

JPH3 0.953 - - - - 0.953 - Mlig455_027357 {REF} {Length: 4050} {Pfam: MORN repeat [PF02493.22, score=88.2]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.0]} {Human: ENSG00000154118, JPH3, junctophilin 3, [RH, Score=391, Expect=2e-122]} {Mouse: ENSMUSG00000025318, Jph3, junctophilin 3, [RH, Score=391, Expect=1e-122]} {Dmel: FBgn0032129, jp, junctophilin, [RH, Score=386, Expect=1e-117]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [RH, Score=379, Expect=4e-118]} {Smed: dd_Smed_v6_4752_0_1, dd_Smed_v6_4752_0_1, [RH, Score=516, Expect=6e-169]} {RNA1509_50399} {RNA1310_28126} {RNA815_32733}
23. MligTC455_35597 38 0.8 Mlig455_027912

Neo: -

Age: Down-Up-Down

0.953 - - - - 0.953 - Mlig455_027912 {REF} {Length: 4150} {TRANSSPLICED} {RNA1509_54389} {RNA1310_1516.1} {RNA815_1066.1}
24. MligTC455_46194 281 5.86 Mlig455_038867

Neo: Irradiation

Age: Up-Down-Down

Region-specific R4: 2.707

Region-enriched R4: 2.107/0.01387

FBXO33 0.953 - - - - 0.953 - Mlig455_038867 {REF} {Length: 3995} {Pfam: F-box-like [PF12937.9, score=24.1]} {Human: ENSG00000165355, FBXO33, F-box protein 33, [RH, Score=73.6, Expect=3e-13]} {Mouse: ENSMUSG00000035329, Fbxo33, F-box protein 33, [RH, Score=70.1, Expect=2e-12]} {Dmel: FBgn0035959, CG4911, [RH, Score=123, Expect=1e-30]} {RNA1509_34211, RNA1509_49549, RNA1509_54797} {RNA1310_15576, RNA1509_34211, RNA1509_49549, RNA1509_54797} {RNA1509_34211, RNA1509_49549, RNA1509_54797, RNA815_6250.1}
25. MligTC455_47070 42 0.88 Mlig455_013541

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_013541 {REF} {Length: 646} {NoTransDecoderORF} {RNA1509_11056} {RNA1310_13305.1} {RNA815_36567}
26. MligTC455_10059 6 0.13 Mlig455_057706

Neo: -

Age: -

0.952 - - - - 0.952 - Mlig455_057706 {REF} {Length: 1119} {TRANSSPLICED} {RNA1310_99869} {RNA815_39526}
27. MligTC455_30241 35 0.72 Mlig455_004299, Mlig455_006286, Mlig455_013663, Mlig455_013676

Neo: -

Age: -

MAP3K19 0.952 - - - - 0.952 -

Mlig455_004299 {REF} {Length: 3294} {Pfam: Protein kinase domain [PF00069.27, score=193.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=146.7]; Ankyrin repeats (3 copies) [PF12796.9, score=76.6]; Ankyrin repeats (many copies) [PF13637.8, score=75.8]; Ankyrin repeats (many copies) [PF13857.8, score=51.4]; Ankyrin repeat [PF13606.8, score=35.7]; Fungal protein kinase [PF17667.3, score=30.8]; Ankyrin repeat [PF00023.32, score=30.6]; ABC1 atypical kinase-like domain [PF03109.18, score=20.7]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=155, Expect=7e-39]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=154, Expect=5e-40]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=138, Expect=4e-34]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=122, Expect=6e-29]} {Smed: dd_Smed_v6_1953_0_1, dd_Smed_v6_1953_0_1, [Score=129, Expect=8e-32]} {RNA1509_45037} {RNA1310_31580} {RNA815_5323.3}

Mlig455_006286 {REF} {Length: 1274} {Pfam: Protein kinase domain [PF00069.27, score=195.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=149.1]; Fungal protein kinase [PF17667.3, score=31.9]; ABC1 atypical kinase-like domain [PF03109.18, score=23.1]; Kinase-like [PF14531.8, score=19.2]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=150, Expect=1e-40]; ENSG00000180815, MAP3K15, mitogen-activated protein kinase kinase kinase 15, [Score=143, Expect=6e-37]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=150, Expect=1e-40]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=140, Expect=1e-36]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=123, Expect=6e-31]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=132, Expect=5e-34]} {RNA1509_45037} {RNA1310_22200.1} {RNA815_5323.2}

Mlig455_013663 {REF} {Length: 2891} {Pfam: Protein kinase domain [PF00069.27, score=177.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.7]; Ankyrin repeats (many copies) [PF13637.8, score=75.3]; Ankyrin repeats (3 copies) [PF12796.9, score=70.2]; Ankyrin repeats (many copies) [PF13857.8, score=52.2]; Ankyrin repeat [PF13606.8, score=32.6]; Fungal protein kinase [PF17667.3, score=30.4]; Ankyrin repeat [PF00023.32, score=27.4]; ABC1 atypical kinase-like domain [PF03109.18, score=20.4]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=136, Expect=1e-32]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=134, Expect=8e-33]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=119, Expect=2e-27]} {Celegans: WBGene00001121, dyf-5, Serine/threonine-protein kinase dyf-5, [Score=109, Expect=6e-25]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=120, Expect=9e-28]} {RNA1509_34593} {RNA1310_25002} {RNA815_5323.1}

Mlig455_013676 {REF} {Length: 3314} {Pfam: Protein kinase domain [PF00069.27, score=176.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.4]; Ankyrin repeats (many copies) [PF13637.8, score=76.4]; Ankyrin repeats (3 copies) [PF12796.9, score=71.0]; Ankyrin repeats (many copies) [PF13857.8, score=49.5]; Ankyrin repeat [PF13606.8, score=32.5]; Fungal protein kinase [PF17667.3, score=29.9]; Ankyrin repeat [PF00023.32, score=28.2]; ABC1 atypical kinase-like domain [PF03109.18, score=19.1]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=131, Expect=7e-31]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=130, Expect=2e-31]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=117, Expect=1e-26]} {Celegans: WBGene00001121, dyf-5, Serine/threonine-protein kinase dyf-5, [Score=110, Expect=3e-25]} {Smed: dd_Smed_v6_9984_0_1, dd_Smed_v6_9984_0_1, [Score=113, Expect=2e-27]} {RNA1509_34593} {RNA1310_25002} {RNA815_5323.1}
28. MligTC455_32942 127 2.65 Mlig455_013414

Neo: -

Age: -

GRID2IP 0.952 - - - - 0.952 - Mlig455_013414 {REF} {Length: 3335} {Pfam: PDZ domain [PF00595.26, score=43.7]; PDZ domain [PF17820.3, score=43.0]; C2 domain [PF00168.32, score=29.7]; PDZ domain [PF13180.8, score=28.8]; Tricorn protease PDZ domain [PF14685.8, score=22.3]; Short myomegalin-like EB1 binding proteins, N-terminal domain [PF18615.3, score=19.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.2]; DDHD domain [PF02862.19, score=18.8]} {Human: ENSG00000215045, GRID2IP, Grid2 interacting protein, [Score=50.8, Expect=7e-06]; ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=50.4, Expect=8e-06]} {Mouse: ENSMUSG00000029101, Rgs12, regulator of G-protein signaling 12, [Score=50.1, Expect=9e-06]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=58.5, Expect=2e-08]} {Smed: dd_Smed_v6_17732_0_1, dd_Smed_v6_17732_0_1, [Score=86.7, Expect=1e-17]} {RNA1310_13395.2} {RNA815_18584}
29. MligTC455_33871 57 1.2 Mlig455_026131, Mlig455_026203

Neo: -

Age: -

P2RX4 0.952 - - - - 0.952 -

Mlig455_026131 {REF} {Length: 534} {NoTransDecoderORF} {RNA1310_145408}

Mlig455_026203 {REF} {Length: 6630} {Pfam: ATP P2X receptor [PF00864.21, score=438.9]} {Human: ENSG00000135124, P2RX4, purinergic receptor P2X 4, [Score=332, Expect=3e-105]} {Mouse: ENSMUSG00000029470, P2rx4, purinergic receptor P2X, ligand-gated ion channel 4, [Score=316, Expect=3e-99]} {Smed: dd_Smed_v6_10968_0_1, dd_Smed_v6_10968_0_1, [RH, Score=431, Expect=3e-142]} {RNA1509_22651} {RNA1310_622.1} {RNA815_2514.1}
30. MligTC455_19316 221 4.6 Mlig455_050415

Neo: Irradiation

Age: -

ZNF626 0.951 - - - - 0.951 - Mlig455_050415 {REF} {Length: 3403} {TRANSSPLICED} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=68.5]; Zinc-finger double domain [PF13465.8, score=68.0]; C2H2-type zinc finger [PF13894.8, score=56.1]; C2H2-type zinc finger [PF13912.8, score=36.3]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=26.1]; Zinc ribbon domain [PF09723.12, score=25.6]; Transposase zinc-ribbon domain [PF12760.9, score=22.3]; Zic proteins zinc finger domain [PF18366.3, score=19.2]} {Human: ENSG00000188171, ZNF626, zinc finger protein 626, [Score=122, Expect=9e-30]} {Mouse: ENSMUSG00000092416, Zfp141, zinc finger protein 141, [Score=112, Expect=4e-26]; ENSMUSG00000074863, Platr25, pluripotency associated transcript 25, [Score=110, Expect=8e-26]; ENSMUSG00000054715, Zscan22, zinc finger and SCAN domain containing 22, [Score=110, Expect=9e-26]; ENSMUSG00000091183, Gm5141, predicted gene 5141, [Score=108, Expect=5e-25]; ENSMUSG00000069476, Zfp616, zinc finger protein 616, [Score=108, Expect=1e-24]; ENSMUSG00000047603, Zfp235, zinc finger protein 235, [Score=107, Expect=1e-24]; ENSMUSG00000030757, Zkscan2, zinc finger with KRAB and SCAN domains 2, [Score=107, Expect=3e-24]; ENSMUSG00000045639, Zfp629, zinc finger protein 629, [Score=107, Expect=3e-24]} {Dmel: FBgn0004618, gl, glass, [Score=112, Expect=2e-26]} {Celegans: WBGene00000483, che-1, Transcription factor che-1, [Score=97.8, Expect=2e-23]} {Smed: dd_Smed_v6_14824_0_1, dd_Smed_v6_14824_0_1, [Score=99.4, Expect=5e-23]} {RNA1509_16295, RNA1509_53463} {RNA1310_10064, RNA1509_16295, RNA1509_53463} {RNA1509_16295, RNA1509_53463, RNA815_10615}
31. MligTC455_23420 136 2.82 Mlig455_020849

Neo: -

Age: Down-Up-Down

AC270292.3 0.951 - - - - 0.951 - Mlig455_020849 {REF} {Length: 1031} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=50.6]; Ankyrin repeat [PF00023.32, score=45.3]; Ankyrin repeat [PF13606.8, score=40.9]; Ankyrin repeats (many copies) [PF13637.8, score=37.1]; Ankyrin repeats (many copies) [PF13857.8, score=32.2]} {Human: ENSG00000285372, AC270292.3, tankyrase, [Score=69.7, Expect=1e-11]; ENSG00000173273, TNKS, tankyrase, [Score=69.3, Expect=1e-11]; ENSG00000101745, ANKRD12, ankyrin repeat domain 12, [Score=68.2, Expect=4e-11]} {Mouse: ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=70.5, Expect=5e-12]; ENSMUSG00000034647, Ankrd12, ankyrin repeat domain 12, [Score=68.6, Expect=1e-11]} {Dmel: FBgn0036814, CG14073, [Score=66.6, Expect=6e-11]} {Celegans: WBGene00001582, gfi-2, GEI-4 (Four) Interacting protein, [Score=52.8, Expect=5e-07]} {Smed: dd_Smed_v6_3062_0_5, dd_Smed_v6_3062_0_5, [Score=65.1, Expect=1e-11]} {RNA1509_48620} {RNA1310_72579.1} {RNA815_23900}
32. MligTC455_29489 117 2.44 Mlig455_018379

Neo: Irradiation

Age: Up-Down-Up, logFC(26M/2M)=-0.551

0.951 - - - - 0.951 - Mlig455_018379 {REF} {Length: 3107} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=54.6]; TcdA/TcdB catalytic glycosyltransferase domain [PF12919.9, score=22.8]; Capsular polysaccharide synthesis protein [PF05704.14, score=22.2]} {Smed: dd_Smed_v6_42389_0_1, dd_Smed_v6_42389_0_1, [Score=109, Expect=2e-27]} {RNA1509_59696} {RNA1310_12293.2, RNA1509_59696} {RNA1509_59696, RNA815_9107.2}
33. MligTC455_37726 70 1.46 Mlig455_058690

Neo: -

Age: -

Region-enriched R4: 4.625/0.04727

0.95 - - - - 0.950 - Mlig455_058690 {REF} {Length: 3017} {NoTransDecoderORF} {RNA1509_54874} {RNA1310_103756} {RNA815_8730.1}
34. MligTC455_37820 68 1.42 Mlig455_060401, Mlig455_069773

Neo: -

Age: -

USP17L12 0.95 - - - - 0.950 -

Mlig455_060401 {REF} {Length: 3216} {Pfam: CG-1 domain [PF03859.18, score=19.8]} {RNA1509_27914} {RNA1310_89165} {RNA815_44825}

Mlig455_069773 {REF} {Length: 379} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=36.9]} {Human: ENSG00000227551, USP17L12, ubiquitin specific peptidase 17-like family member 12, [Score=45.8, Expect=3e-06]; ENSG00000249811, USP17L21, ubiquitin specific peptidase 17-like family member 21, [Score=45.8, Expect=3e-06]; ENSG00000055483, USP36, ubiquitin specific peptidase 36, [Score=44.7, Expect=5e-06]} {Mouse: ENSMUSG00000033909, Usp36, ubiquitin specific peptidase 36, [Score=44.7, Expect=6e-06]; ENSMUSG00000051306, Usp42, ubiquitin specific peptidase 42, [Score=43.9, Expect=1e-05]} {RNA1310_138296} {RNA815_44825}
35. MligTC455_41023 267 5.56 Mlig455_010533, Mlig455_061800, Mlig455_061841

Neo: Int S/G2/M

Age: Down-Up-Up, logFC(26M/2M)=0.367

FAM206A 0.95 - - - - 0.950 -

Mlig455_010533 {REF} {Length: 1349} {TRANSSPLICED} {Pfam: Glycine cleavage H-protein [PF01597.21, score=23.6]} {Human: ENSG00000119328, FAM206A, family with sequence similarity 206 member A, [RH, Score=78.2, Expect=1e-17]} {Mouse: ENSMUSG00000038827, Fam206a, family with sequence similarity 206, member A, [RH, Score=80.5, Expect=8e-19]} {Dmel: FBgn0260464, CG9288, [RH, Score=63.9, Expect=2e-12]} {Smed: dd_Smed_v6_6274_0_1, dd_Smed_v6_6274_0_1, [RH, Score=62.0, Expect=3e-12]} {RNA1509_30206} {RNA1310_36222} {RNA815_20614}

Mlig455_061800 {REF} {Length: 1355} {TRANSSPLICED} {Pfam: Glycine cleavage H-protein [PF01597.21, score=23.6]} {Human: ENSG00000119328, FAM206A, family with sequence similarity 206 member A, [RH, Score=78.2, Expect=1e-17]} {Mouse: ENSMUSG00000038827, Fam206a, family with sequence similarity 206, member A, [RH, Score=80.5, Expect=8e-19]} {Dmel: FBgn0260464, CG9288, [RH, Score=63.9, Expect=2e-12]} {Smed: dd_Smed_v6_6274_0_1, dd_Smed_v6_6274_0_1, [RH, Score=62.0, Expect=3e-12]} {RNA1509_30206} {RNA1310_36222, RNA1509_30206} {RNA1509_30206, RNA815_20614}

Mlig455_061841 {REF} {Length: 1348} {TRANSSPLICED} {Pfam: Glycine cleavage H-protein [PF01597.21, score=23.6]} {Human: ENSG00000119328, FAM206A, family with sequence similarity 206 member A, [RH, Score=78.2, Expect=1e-17]} {Mouse: ENSMUSG00000038827, Fam206a, family with sequence similarity 206, member A, [RH, Score=80.5, Expect=8e-19]} {Dmel: FBgn0260464, CG9288, [RH, Score=63.9, Expect=2e-12]} {Smed: dd_Smed_v6_6274_0_1, dd_Smed_v6_6274_0_1, [RH, Score=62.0, Expect=3e-12]} {RNA1509_30206} {RNA1310_36222} {RNA815_20614}
36. MligTC455_50740 262 5.46 Mlig455_028088

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.630/0.00016

SFRP5 0.95 - - - - 0.950 - Mlig455_028088 {REF} {Length: 2548} {Pfam: Fz domain [PF01392.24, score=93.7]} {Human: ENSG00000120057, SFRP5, secreted frizzled related protein 5, [RH, Score=158, Expect=5e-44]} {Mouse: ENSMUSG00000018822, Sfrp5, secreted frizzled-related sequence protein 5, [RH, Score=156, Expect=2e-43]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=4e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=2e-46]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=164, Expect=2e-46]} {RNA1509_19129} {RNA1310_15120} {RNA815_30861}

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