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Results for MligTC455_03503

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_03503 75 1.57 Mlig455_042645

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.368

 Mlig455_042645 {REF} {Length: 2491} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=36.7]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=77.8, Expect=2e-15]} {RNA1509_19205, RNA1509_53675} {RNA1310_10802.1, RNA1509_19205, RNA1509_53675} {RNA1509_19205, RNA1509_53675, RNA815_4389.1}

Cumulative graph for MligTC455_03503

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.34 1.634 0.78030 1.00000
RegionR2 -0.515 1.634 0.96727 1.00000
RegionR3 -0.688 1.634 0.97672 1.00000
RegionR4 1.49 1.634 0.32116 0.63802
RegionR5 -0.178 1.634 0.90954 1.00000
RegionR6 0.258 1.634 0.77622 1.00000
RegionR7 1.547 1.634 0.25912 0.88630
RegionR8 -0.573 1.634 0.97257 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.881 1.634 0.99980 1.00000
RegenerationR2 1.122 1.634 0.06995 0.43061
RegenerationR3 0.44 1.634 0.70106 0.94783
RegenerationR4 0.109 1.634 0.92573 1.00000
RegenerationR5 0.518 1.634 0.58034 0.90079
RegenerationR6 -1.144 1.634 0.25330 0.60300
RegenerationBL 0.573 1.634 0.63954 0.97833
RegenerationTP -1.185 1.634 0.51216 0.90925


Genes with expression patterns similar to MligTC455_03503

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_03503 75 1.57 Mlig455_042645

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.368

 4 - - 1.000 1.000 1.000 1.000 Mlig455_042645 {REF} {Length: 2491} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=36.7]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=77.8, Expect=2e-15]} {RNA1509_19205, RNA1509_53675} {RNA1310_10802.1, RNA1509_19205, RNA1509_53675} {RNA1509_19205, RNA1509_53675, RNA815_4389.1}
2. MligTC455_10428 1232 25.66 Mlig455_031930, Mlig455_032667

Neo: -

Age: logFC(26M/2M)=-0.438

 WDR66 3.374 - - 0.785 0.885 0.966 0.738

Mlig455_031930 {REF} {Length: 4976} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=69.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.4]; Rab3 GTPase-activating protein regulatory subunit N-terminus [PF14655.8, score=18.5]} {Human: ENSG00000158023, WDR66, WD repeat domain 66, [Score=492, Expect=1e-158]} {Mouse: ENSMUSG00000029442, Wdr66, WD repeat domain 66, [Score=487, Expect=4e-153]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=58.5, Expect=3e-08]} {Smed: dd_Smed_v6_11127_0_2, dd_Smed_v6_11127_0_2, [Score=655, Expect=0.0]} {RNA1509_16171} {RNA1310_3690} {RNA815_918.1}

Mlig455_032667 {REF} {Length: 4277} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=81.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=24.8]} {Human: ENSG00000158023, WDR66, WD repeat domain 66, [RH, Score=779, Expect=0.0]} {Mouse: ENSMUSG00000029442, Wdr66, WD repeat domain 66, [RH, Score=771, Expect=0.0]} {Dmel: FBgn0039867, CstF50, Cleavage stimulation factor 50 kD subunit, [Score=51.2, Expect=5e-06]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=68.9, Expect=2e-11]} {Smed: dd_Smed_v6_11127_0_2, dd_Smed_v6_11127_0_2, [RH, Score=939, Expect=0.0]} {RNA1509_3046} {RNA1310_3690} {RNA815_918.1}
3. MligTC455_32306 476 9.91 Mlig455_011146

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.714

 3.284 - - 0.826 0.952 0.800 0.706 Mlig455_011146 {REF} {Length: 15000} {RNA1509_4044, RNA1509_4722} {RNA1310_655.1, RNA1509_4044} {RNA1509_4044, RNA815_335.1}
4. MligTC455_32942 127 2.65 Mlig455_013414

Neo: -

Age: -

 GRID2IP 2.713 - - 0.859 0.895 0.959 - Mlig455_013414 {REF} {Length: 3335} {Pfam: PDZ domain [PF00595.26, score=43.7]; PDZ domain [PF17820.3, score=43.0]; C2 domain [PF00168.32, score=29.7]; PDZ domain [PF13180.8, score=28.8]; Tricorn protease PDZ domain [PF14685.8, score=22.3]; Short myomegalin-like EB1 binding proteins, N-terminal domain [PF18615.3, score=19.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.2]; DDHD domain [PF02862.19, score=18.8]} {Human: ENSG00000215045, GRID2IP, Grid2 interacting protein, [Score=50.8, Expect=7e-06]; ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=50.4, Expect=8e-06]} {Mouse: ENSMUSG00000029101, Rgs12, regulator of G-protein signaling 12, [Score=50.1, Expect=9e-06]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=58.5, Expect=2e-08]} {Smed: dd_Smed_v6_17732_0_1, dd_Smed_v6_17732_0_1, [Score=86.7, Expect=1e-17]} {RNA1310_13395.2} {RNA815_18584}
5. MligTC455_41139 569 11.86 Mlig455_001282

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.661

 SLC6A3 2.689 - - - 0.968 0.942 0.779 Mlig455_001282 {REF} {Length: 2522} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=533.2]} {Human: ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=451, Expect=1e-150]; ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=451, Expect=1e-150]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=439, Expect=8e-146]} {Mouse: ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=452, Expect=3e-151]; ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=443, Expect=9e-148]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [Score=420, Expect=8e-139]} {Celegans: WBGene00003387, mod-5, Transporter, [Score=371, Expect=1e-119]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [Score=497, Expect=1e-168]} {RNA1509_9639} {RNA1310_4480.1, RNA1509_9639} {RNA1509_9639, RNA815_1493}
6. MligTC455_24781 664 13.83 Mlig455_056890

Neo: -

Age: -

 TTLL3 2.556 - - - 0.843 0.952 0.761 Mlig455_056890 {REF} {Length: 4523} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=246.0]; YheC/D like ATP-grasp [PF14398.8, score=22.3]} {Human: ENSG00000214021, TTLL3, tubulin tyrosine ligase like 3, [Score=419, Expect=7e-138]; ENSG00000138892, TTLL8, tubulin tyrosine ligase like 8, [Score=417, Expect=5e-133]} {Mouse: ENSMUSG00000030276, Ttll3, tubulin tyrosine ligase-like family, member 3, [Score=451, Expect=3e-145]; ENSMUSG00000022388, Ttll8, tubulin tyrosine ligase-like family, member 8, [Score=434, Expect=8e-140]} {Dmel: FBgn0031854, TTLL3A, Tubulin tyrosine ligase-like 3A, [Score=267, Expect=2e-76]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=113, Expect=1e-26]} {Smed: dd_Smed_v6_10244_0_3, dd_Smed_v6_10244_0_3, [Score=549, Expect=0.0]} {RNA1509_39964, RNA1509_51119, RNA1509_8170} {RNA1310_3822, RNA1509_39964, RNA1509_51119} {RNA1509_39964, RNA1509_51119, RNA815_867}
7. MligTC455_24063 339 7.06 Mlig455_048182

Neo: -

Age: Down-Down-Up

 DYNLL1 2.447 - - 0.785 0.956 0.706 - Mlig455_048182 {REF} {Length: 1157} {Pfam: Dynein light chain type 1 [PF01221.20, score=64.3]; EF hand [PF13202.8, score=43.3]; EF hand [PF00036.34, score=35.7]; EF-hand domain pair [PF13499.8, score=35.5]; EF-hand domain [PF13405.8, score=29.0]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=60.1, Expect=1e-11]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=60.1, Expect=1e-11]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=60.1, Expect=7e-12]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=60.1, Expect=7e-12]; ENSMUSG00000064063, BC048507, cDNA sequence BC048507, [Score=58.9, Expect=2e-11]} {Dmel: FBgn0011760, ctp, cut up, [Score=57.0, Expect=7e-11]} {Celegans: WBGene00001005, dlc-1, Dynein light chain 1, cytoplasmic, [Score=57.0, Expect=5e-11]} {Smed: dd_Smed_v6_9661_0_1, dd_Smed_v6_9661_0_1, [RH, Score=153, Expect=2e-47]} {RNA1509_6272} {RNA1310_31271} {RNA815_14002}
8. MligTC455_30713 277 5.78 Mlig455_044000, Mlig455_050688

Neo: -

Age: -

 TTLL9 2.414 - - - 0.719 0.950 0.745

Mlig455_044000 {REF} {Length: 2900} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=293.3]; YheC/D like ATP-grasp [PF14398.8, score=28.0]; Sugar-transfer associated ATP-grasp [PF14397.8, score=19.3]} {Human: ENSG00000131044, TTLL9, tubulin tyrosine ligase like 9, [RH, Score=500, Expect=9e-177]} {Mouse: ENSMUSG00000074673, Ttll9, tubulin tyrosine ligase-like family, member 9, [RH, Score=542, Expect=0.0]} {Dmel: FBgn0052238, CG32238, [Score=314, Expect=1e-102]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [RH, Score=383, Expect=9e-131]} {Smed: dd_Smed_v6_13605_0_1, dd_Smed_v6_13605_0_1, [RH, Score=529, Expect=0.0]} {RNA1509_23575, RNA1509_38415, RNA1509_39587} {RNA1310_6106, RNA1509_23575, RNA1509_38415, RNA1509_39587} {RNA1509_23575, RNA1509_38415, RNA1509_39587, RNA815_8243}

Mlig455_050688 {REF} {Length: 3812} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=291.5]; YheC/D like ATP-grasp [PF14398.8, score=25.9]} {Human: ENSG00000131044, TTLL9, tubulin tyrosine ligase like 9, [RH, Score=509, Expect=3e-175]} {Mouse: ENSMUSG00000074673, Ttll9, tubulin tyrosine ligase-like family, member 9, [RH, Score=553, Expect=0.0]} {Dmel: FBgn0052238, CG32238, [Score=317, Expect=2e-99]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [RH, Score=387, Expect=8e-128]} {Smed: dd_Smed_v6_13605_0_1, dd_Smed_v6_13605_0_1, [RH, Score=539, Expect=0.0]} {RNA1509_38415} {RNA1310_6106} {RNA815_8243}
9. MligTC455_46417 37 0.76 Mlig455_061456

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.955

 HDAC4 1.903 - - - 0.944 0.959 - Mlig455_061456 {REF} {Length: 4466} {Pfam: Histone deacetylase domain [PF00850.21, score=276.3]} {Human: ENSG00000068024, HDAC4, histone deacetylase 4, [RH, Score=410, Expect=5e-130]; ENSG00000048052, HDAC9, histone deacetylase 9, [RH, Score=397, Expect=5e-124]} {Mouse: ENSMUSG00000026313, Hdac4, histone deacetylase 4, [RH, Score=413, Expect=2e-130]} {Dmel: FBgn0041210, HDAC4, Histone deacetylase 4, [Score=373, Expect=2e-114]} {Celegans: WBGene00001837, hda-4, Histone deacetylase 4, [Score=363, Expect=8e-114]} {Smed: dd_Smed_v6_9385_0_1, dd_Smed_v6_9385_0_1, [Score=418, Expect=4e-135]} {RNA1509_7849} {RNA1310_71485} {RNA815_10834}
10. MligTC455_20241 106 2.21 Mlig455_064205

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.589

 1.887 - - 0.922 - 0.965 - Mlig455_064205 {REF} {Length: 1849} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=62.8, Expect=2e-11]} {RNA1509_7841} {RNA1310_18810} {RNA815_3607}
11. MligTC455_35536 441 9.18 Mlig455_035025

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.417

 ACSF2 1.862 - - - 0.960 0.902 - Mlig455_035025 {REF} {Length: 2465} {Pfam: AMP-binding enzyme [PF00501.30, score=347.8]; AMP-binding enzyme C-terminal domain [PF13193.8, score=65.1]} {Human: ENSG00000167107, ACSF2, acyl-CoA synthetase family member 2, [RH, Score=538, Expect=0.0]} {Mouse: ENSMUSG00000076435, Acsf2, acyl-CoA synthetase family member 2, [RH, Score=553, Expect=0.0]} {Dmel: FBgn0031703, CG12512, [RH, Score=469, Expect=3e-158]} {Celegans: WBGene00018488, acs-1, Fatty Acid CoA Synthetase family, [RH, Score=567, Expect=0.0]} {Smed: dd_Smed_v6_10135_0_1, dd_Smed_v6_10135_0_1, [Score=175, Expect=2e-47]} {RNA1509_13785, RNA1509_18209, RNA1509_36737} {RNA1310_8993.1, RNA1509_13785, RNA1509_18209, RNA1509_36737} {RNA1509_13785, RNA1509_18209, RNA1509_36737, RNA815_3019}
12. MligTC455_10429 789 16.44 Mlig455_070400

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.548

 WDR66 1.841 - - - 0.876 0.965 - Mlig455_070400 {REF} {Length: 5313} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=80.7]; Cornifin (SPRR) family [PF02389.17, score=34.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=24.9]} {Human: ENSG00000158023, WDR66, WD repeat domain 66, [RH, Score=780, Expect=0.0]} {Mouse: ENSMUSG00000029442, Wdr66, WD repeat domain 66, [RH, Score=769, Expect=0.0]} {Dmel: FBgn0039867, CstF50, Cleavage stimulation factor 50 kD subunit, [Score=51.2, Expect=5e-06]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=67.8, Expect=6e-11]} {Smed: dd_Smed_v6_11127_0_2, dd_Smed_v6_11127_0_2, [RH, Score=943, Expect=0.0]} {RNA1509_3046} {RNA1310_3690} {RNA815_918.1}
13. MligTC455_03504 344 7.16 Mlig455_042601, Mlig455_042680

Neo: -

Age: -

 TRIM71 1.833 - - - 0.953 0.880 -

Mlig455_042601 {REF} {Length: 1944} {TRANSSPLICED} {Pfam: B-box zinc finger [PF00643.26, score=52.4]} {Human: ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=62.8, Expect=7e-10]} {Dmel: FBgn0031999, CG8419, [Score=55.5, Expect=9e-08]} {Smed: dd_Smed_v6_8395_0_1, dd_Smed_v6_8395_0_1, [Score=107, Expect=2e-24]} {RNA1509_53675} {RNA1310_29759} {RNA815_39084}

Mlig455_042680 {REF} {Length: 2304} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=36.6]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=77.8, Expect=3e-15]} {RNA1509_19205} {RNA1310_10802.1} {RNA815_4389.1}
14. MligTC455_23412 90 1.88 Mlig455_015964

Neo: -

Age: Down-Up-Down

 1.825 - - 0.952 - 0.873 - Mlig455_015964 {REF} {Length: 4024} {Pfam: Intra-flagellar transport protein 57 [PF10498.11, score=19.8]} {RNA1509_46835} {RNA1310_11201.1} {RNA815_31251}
15. MligTC455_19761 138 2.87 Mlig455_014482

Neo: -

Age: -

 TLL1 1.78 - - - 0.956 - 0.824 Mlig455_014482 {REF} {Length: 2610} {Pfam: CUB domain [PF00431.22, score=133.6]; CUB-like domain [PF02408.22, score=39.7]} {Human: ENSG00000038295, TLL1, tolloid like 1, [Score=88.2, Expect=2e-17]} {Mouse: ENSMUSG00000047517, Dmbt1, deleted in malignant brain tumors 1, [Score=139, Expect=2e-33]} {Dmel: FBgn0003719, tld, tolloid, [Score=59.7, Expect=6e-09]} {Celegans: WBGene00013855, ZC116.3, Probable cubilin, [Score=55.1, Expect=2e-07]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=96.7, Expect=1e-20]} {RNA1509_60025} {RNA1310_15896, RNA1509_60025} {RNA1509_60025, RNA815_23387}
16. MligTC455_44635 298 6.21 Mlig455_066235

Neo: -

Age: -

 CCDC89 1.764 - - - - 0.963 0.801 Mlig455_066235 {REF} {Length: 2245} {TRANSSPLICED} {Human: ENSG00000179071, CCDC89, coiled-coil domain containing 89, [RH, Score=121, Expect=1e-30]} {Mouse: ENSMUSG00000044362, Ccdc89, coiled-coil domain containing 89, [RH, Score=118, Expect=7e-30]} {Smed: dd_Smed_v6_41_2_1, dd_Smed_v6_41_2_1, [RH, Score=67.4, Expect=1e-13]} {RNA1509_12755, RNA1509_43101} {RNA1310_8733, RNA1509_12755, RNA1509_43101} {RNA1509_12755, RNA1509_43101, RNA815_8009.1}
17. MligTC455_43322 67 1.4 Mlig455_032888

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.946

Region-enriched R2: 7.587/0.00001

 1.758 - - 0.807 0.951 - - Mlig455_032888 {REF} {Length: 2179} {RNA1509_40507, RNA1509_49821} {RNA1310_22780, RNA1509_40507} {RNA1509_40507, RNA815_9762}
18. MligTC455_45197 938 19.54 Mlig455_052429

Neo: -

Age: -

 ANKRD44 1.753 - - 0.799 0.954 - - Mlig455_052429 {REF} {Length: 3376} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=125.4]; Ankyrin repeats (many copies) [PF13637.8, score=101.6]; Ankyrin repeats (many copies) [PF13857.8, score=90.3]; Ankyrin repeat [PF13606.8, score=72.4]; Ankyrin repeat [PF00023.32, score=54.1]} {Human: ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=110, Expect=1e-24]; ENSG00000119509, INVS, inversin, [Score=110, Expect=5e-24]; ENSG00000139645, ANKRD52, ankyrin repeat domain 52, [Score=107, Expect=5e-23]} {Mouse: ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=107, Expect=2e-23]; ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=106, Expect=4e-23]} {Dmel: FBgn0260487, CG42534, [Score=109, Expect=4e-24]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [Score=95.5, Expect=5e-20]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [Score=112, Expect=4e-25]} {RNA1509_13535, RNA1509_8541} {RNA1310_5307.1, RNA1509_13535, RNA1509_8541} {RNA1509_13535, RNA1509_8541, RNA815_942}
19. MligTC455_41673 26 0.54 Mlig455_035834

Neo: -

Age: -

 1.684 - - - - 0.962 0.722 Mlig455_035834 {REF} {Length: 1561} {NoTransDecoderORF} {RNA1310_64046} {RNA815_37581}
20. MligTC455_45357 32 0.66 Mlig455_062549

Neo: -

Age: -

 1.678 - - - - 0.951 0.727 Mlig455_062549 {REF} {Length: 2469} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=72.8]} {RNA1310_136483}
21. MligTC455_25153 368 7.66 Mlig455_040073

Neo: -

Age: -

Region-enriched R5: 3.037/0.00000

 0.972 - - - 0.972 - - Mlig455_040073 {REF} {Length: 2051} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=38.7]; TcdA/TcdB catalytic glycosyltransferase domain [PF12919.9, score=20.1]} {Smed: dd_Smed_v6_2982_0_2, dd_Smed_v6_2982_0_2, [Score=83.2, Expect=5e-18]} {RNA1509_20770} {RNA1310_16534} {RNA815_6249}
22. MligTC455_20421 31 0.65 Mlig455_010709

Neo: -

Age: -

Region-enriched R7: 3.787/0.04771

 0.969 - - 0.969 - - - Mlig455_010709 {REF} {Length: 2034} {RNA1310_48353}
23. MligTC455_22613 61 1.28 Mlig455_027104

Neo: -

Age: -

 FYN 0.966 - - - - 0.966 - Mlig455_027104 {REF} {Length: 3199} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=253.8]; Protein kinase domain [PF00069.27, score=164.0]; SH3 domain [PF00018.30, score=35.8]; Variant SH3 domain [PF07653.19, score=34.4]; SH2 domain [PF00017.26, score=33.0]; Variant SH3 domain [PF14604.8, score=30.8]; Bacterial SH3 domain [PF08239.13, score=24.5]; Kinase-like [PF14531.8, score=18.6]; ABC1 atypical kinase-like domain [PF03109.18, score=18.3]} {Human: ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=280, Expect=6e-87]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=274, Expect=6e-85]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=272, Expect=2e-84]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=268, Expect=6e-83]} {Mouse: ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=280, Expect=5e-87]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=276, Expect=6e-86]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=269, Expect=2e-83]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=266, Expect=7e-82]} {Dmel: FBgn0262733, Src64B, Src oncogene at 64B, [Score=271, Expect=6e-84]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=278, Expect=2e-87]} {Smed: dd_Smed_v6_3363_0_1, dd_Smed_v6_3363_0_1, [Score=313, Expect=8e-101]} {RNA1509_37079} {RNA1310_14637} {RNA815_4860}
24. MligTC455_19954 17 0.35 Mlig455_049736

Neo: Int S/G2/M

Age: -

 0.965 - - - - 0.965 - Mlig455_049736 {REF} {Length: 692} {NoTransDecoderORF} {RNA1310_78373}
25. MligTC455_00349 7 0.15 Mlig455_069175

Neo: -

Age: -

 0.963 - - - - 0.963 - Mlig455_069175 {REF} {Length: 639} {RNA1310_21320}
26. MligTC455_21336 45 0.93 Mlig455_027703

Neo: -

Age: -

 0.963 - - - - 0.963 - Mlig455_027703 {REF} {Length: 3524} {NoTransDecoderORF} {RNA1509_50956} {RNA1310_80971} {RNA815_6115.1}
27. MligTC455_42968 1407 29.31 Mlig455_016645

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.499

 CCDC105 0.962 - - - - 0.962 - Mlig455_016645 {REF} {Length: 2773} {Pfam: Tektin family [PF03148.16, score=79.1]} {Human: ENSG00000160994, CCDC105, coiled-coil domain containing 105, [RH, Score=121, Expect=1e-29]} {Mouse: ENSMUSG00000078442, Ccdc105, coiled-coil domain containing 105, [RH, Score=131, Expect=3e-33]} {Smed: dd_Smed_v6_14773_0_1, dd_Smed_v6_14773_0_1, [RH, Score=226, Expect=3e-70]} {RNA1509_10605, RNA1509_18742, RNA1509_43341} {RNA1310_6775.1, RNA1509_10605, RNA1509_18742, RNA1509_43341} {RNA1509_10605, RNA1509_18742, RNA1509_43341, RNA815_2314.1}
28. MligTC455_27537 384 8 Mlig455_006514, Mlig455_006630

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.415

Region-enriched R4: 5.650/0.00051

 CRB2, NOTCH2 0.961 - - - - 0.961 -

Mlig455_006514 {REF} {Length: 4855} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=175.4]; Human growth factor-like EGF [PF12661.9, score=89.0]; Laminin G domain [PF02210.26, score=30.6]} {Human: ENSG00000134250, NOTCH2, notch 2, [Score=263, Expect=2e-70]} {Mouse: ENSMUSG00000027878, Notch2, notch 2, [Score=262, Expect=3e-70]} {Dmel: FBgn0004647, N, Notch, [Score=258, Expect=3e-69]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=191, Expect=2e-48]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=187, Expect=1e-47]} {RNA1509_54879} {RNA1310_14888.1} {RNA815_9776.1}

Mlig455_006630 {REF} {Length: 4640} {Pfam: EGF-like domain [PF00008.29, score=165.3]; Human growth factor-like EGF [PF12661.9, score=85.9]; Laminin G domain [PF02210.26, score=31.0]} {Human: ENSG00000148204, CRB2, crumbs 2, cell polarity complex component, [Score=334, Expect=1e-95]} {Mouse: ENSMUSG00000035403, Crb2, crumbs family member 2, [Score=333, Expect=5e-95]} {Dmel: FBgn0259685, crb, crumbs, [Score=422, Expect=5e-123]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=237, Expect=5e-63]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=253, Expect=5e-68]} {RNA1509_54879} {RNA1310_14888.1} {RNA815_693.1}
29. MligTC455_32586 97 2.02 Mlig455_052753

Neo: Irradiation

Age: -

Region-enriched R5: 2.108/0.03498

 0.961 - - - - 0.961 - Mlig455_052753 {REF} {Length: 1463} {TRANSSPLICED} {RNA1509_48403} {RNA1310_44079, RNA1509_48403} {RNA1509_48403, RNA815_21852}
30. MligTC455_03798 7 0.15 Mlig455_010797

Neo: -

Age: -

 0.96 - - - - 0.960 - Mlig455_010797 {REF} {Length: 1274} {RNA1310_143257}
31. MligTC455_13416 16 0.33 Mlig455_046199

Neo: -

Age: -

 0.96 - - - - 0.960 - Mlig455_046199 {REF} {Length: 168} {NoTransDecoderORF}
32. MligTC455_52337 291 6.07 Mlig455_008793

Neo: -

Age: -

 C2orf76 0.96 - - 0.960 - - - Mlig455_008793 {REF} {Length: 2094} {TRANSSPLICED} {Pfam: Uncharacterized conserved protein (DUF2340) [PF10209.11, score=127.1]} {Human: ENSG00000186132, C2orf76, chromosome 2 open reading frame 76, [RH, Score=97.1, Expect=3e-26]} {Mouse: ENSMUSG00000026388, 3110009E18Rik, RIKEN cDNA 3110009E18 gene, [RH, Score=92.0, Expect=2e-24]} {RNA1509_25259} {RNA1310_9901.1} {RNA815_28452}
33. MligTC455_06713 7 0.15 Mlig455_053256

Neo: -

Age: -

 0.959 - - - - 0.959 - Mlig455_053256 {REF} {Length: 357} {NoTransDecoderORF} {RNA1310_145656}
34. MligTC455_10476 3 0.07 Mlig455_031071

Neo: -

Age: logFC(26M/2M)=-1.165

 MAP1A 0.959 - - - - 0.959 - Mlig455_031071 {REF} {Length: 2600} {Pfam: Family of unknown function (DUF5892) [PF19243.1, score=77.2]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=28.1]; Prokaryotic RING finger family 4 [PF14447.8, score=21.8]} {Human: ENSG00000166963, MAP1A, microtubule associated protein 1A, [Score=85.5, Expect=1e-16]} {RNA1509_14834} {RNA1310_38934} {RNA815_20717}
35. MligTC455_14764 12 0.25 Mlig455_021050

Neo: -

Age: -

 0.959 - - - - 0.959 - Mlig455_021050 {REF} {Length: 2226} {RNA1310_91563}
36. MligTC455_18550 27 0.57 Mlig455_003630

Neo: Germline

Age: logFC(26M/2M)=-0.849

 0.959 - - - - 0.959 - Mlig455_003630 {REF} {Length: 2511} {RNA1509_32165} {RNA1310_13450} {RNA815_5462.1}
37. MligTC455_47819 9 0.2 Mlig455_033339, Mlig455_059759

Neo: -

Age: -

 0.959 - - - - 0.959 -

Mlig455_033339 {REF} {Length: 1057} {RNA1509_48033} {RNA1310_58376} {RNA815_51419}

Mlig455_059759 {REF} {Length: 109} {NoTransDecoderORF} {RNA1310_58376} {RNA815_51419}
38. MligTC455_13079 125 2.61 Mlig455_007628, Mlig455_020961

Neo: -

Age: -

 0.958 - - - - 0.958 -

Mlig455_007628 {REF} {Length: 1164} {RNA1509_16706} {RNA1310_88024} {RNA815_39833}

Mlig455_020961 {REF} {Length: 1442} {NoTransDecoderORF} {RNA1310_88024} {RNA815_39833}
39. MligTC455_13417 13 0.26 Mlig455_009840, Mlig455_010346

Neo: -

Age: -

 0.958 - - - - 0.958 -

Mlig455_009840 {REF} {Length: 1027} {NoTransDecoderORF} {RNA1310_124106} {RNA815_30229.1}

Mlig455_010346 {REF} {Length: 658} {NoTransDecoderORF} {RNA1310_124106} {RNA815_30229.1}
40. MligTC455_26374 149 3.1 Mlig455_043184

Neo: -

Age: -

 DDB1 0.958 - - - - 0.958 - Mlig455_043184 {REF} {Length: 7206} {Pfam: Mono-functional DNA-alkylating methyl methanesulfonate N-term [PF10433.11, score=293.5]; CPSF A subunit region [PF03178.17, score=224.4]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=38.6]} {Human: ENSG00000167986, DDB1, damage specific DNA binding protein 1, [RH, Score=971, Expect=0.0]} {Mouse: ENSMUSG00000024740, Ddb1, damage specific DNA binding protein 1, [RH, Score=976, Expect=0.0]} {Dmel: FBgn0260962, pic, piccolo, [RH, Score=883, Expect=0.0]} {Celegans: WBGene00010890, ddb-1, DNA damage-binding protein 1, [RH, Score=592, Expect=0.0]} {Smed: dd_Smed_v6_4952_0_1, dd_Smed_v6_4952_0_1, [RH, Score=598, Expect=0.0]} {RNA1509_6460} {RNA1310_1777.1} {RNA815_1989}
41. MligTC455_37820 68 1.42 Mlig455_060401, Mlig455_069773

Neo: -

Age: -

 USP17L12 0.958 - - - - 0.958 -

Mlig455_060401 {REF} {Length: 3216} {Pfam: CG-1 domain [PF03859.18, score=19.8]} {RNA1509_27914} {RNA1310_89165} {RNA815_44825}

Mlig455_069773 {REF} {Length: 379} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=36.9]} {Human: ENSG00000227551, USP17L12, ubiquitin specific peptidase 17-like family member 12, [Score=45.8, Expect=3e-06]; ENSG00000249811, USP17L21, ubiquitin specific peptidase 17-like family member 21, [Score=45.8, Expect=3e-06]; ENSG00000055483, USP36, ubiquitin specific peptidase 36, [Score=44.7, Expect=5e-06]} {Mouse: ENSMUSG00000033909, Usp36, ubiquitin specific peptidase 36, [Score=44.7, Expect=6e-06]; ENSMUSG00000051306, Usp42, ubiquitin specific peptidase 42, [Score=43.9, Expect=1e-05]} {RNA1310_138296} {RNA815_44825}
42. MligTC455_42706 23 0.47 Mlig455_069209

Neo: -

Age: -

 0.958 - - - - 0.958 - Mlig455_069209 {REF} {Length: 1678} {RNA1310_62984} {RNA815_26444}
43. MligTC455_40349 84 1.74 Mlig455_050726

Neo: -

Age: Down-Up-Up

 0.957 - - - - 0.957 - Mlig455_050726 {REF} {Length: 2409} {Pfam: NHL repeat [PF01436.23, score=32.4]} {RNA1509_56255} {RNA1310_46961} {RNA815_45776}
44. MligTC455_01226 14 0.3 Mlig455_018203

Neo: -

Age: -

 0.956 - - - - 0.956 - Mlig455_018203 {REF} {Length: 673} {NoTransDecoderORF} {RNA1509_35533} {RNA1310_93416} {RNA815_17588}
45. MligTC455_03581 18 0.38 Mlig455_059916

Neo: -

Age: logFC(26M/2M)=0.621

 CUBN 0.956 - - - - 0.956 - Mlig455_059916 {REF} {Length: 4313} {Pfam: CUB domain [PF00431.22, score=244.9]; CUB-like domain [PF02408.22, score=39.5]} {Human: ENSG00000107611, CUBN, cubilin, [Score=108, Expect=8e-23]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=110, Expect=1e-23]} {Dmel: FBgn0259140, CG42255, [Score=58.9, Expect=4e-08]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [Score=56.6, Expect=1e-07]} {RNA1509_23989} {RNA1310_1198.1} {RNA815_345.1}
46. MligTC455_34642 348 7.25 Mlig455_027101

Neo: -

Age: -

 ATP2A1 0.956 - - - - 0.956 - Mlig455_027101 {REF} {Length: 4381} {TRANSSPLICED} {Pfam: E1-E2 ATPase [PF00122.22, score=191.7]; Cation transporting ATPase, C-terminus [PF00689.23, score=144.6]; Cation transport ATPase (P-type) [PF13246.8, score=76.4]; haloacid dehalogenase-like hydrolase [PF00702.28, score=73.8]; Cation transporter/ATPase, N-terminus [PF00690.28, score=67.0]; haloacid dehalogenase-like hydrolase [PF12710.9, score=30.5]; haloacid dehalogenase-like hydrolase [PF08282.14, score=30.2]} {Human: ENSG00000196296, ATP2A1, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, [RH, Score=1462, Expect=0.0]; ENSG00000174437, ATP2A2, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2, [RH, Score=1446, Expect=0.0]; ENSG00000074370, ATP2A3, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3, [RH, Score=1403, Expect=0.0]} {Mouse: ENSMUSG00000030730, Atp2a1, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1, [RH, Score=1456, Expect=0.0]; ENSMUSG00000029467, Atp2a2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, [RH, Score=1451, Expect=0.0]; ENSMUSG00000020788, Atp2a3, ATPase, Ca++ transporting, ubiquitous, [RH, Score=1407, Expect=0.0]} {Dmel: FBgn0263006, SERCA, Sarco/endoplasmic reticulum Ca(2+)-ATPase, [RH, Score=1493, Expect=0.0]} {Celegans: WBGene00004736, sca-1, Calcium-transporting ATPase, [RH, Score=1467, Expect=0.0]} {Smed: dd_Smed_v6_1772_0_1, dd_Smed_v6_1772_0_1, [RH, Score=1614, Expect=0.0]} {RNA1509_20343, RNA1509_42455} {RNA1310_3029.1, RNA1509_42455} {RNA1509_42455, RNA815_2104.2}
47. MligTC455_41223 75 1.57 Mlig455_064371, Mlig455_064398

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.711

 TNKS2 0.956 - - - - 0.956 -

Mlig455_064371 {REF} {Length: 1874} {Pfam: Poly(ADP-ribose) polymerase catalytic domain [PF00644.22, score=109.1]; ADP-Ribosyltransferase in polyvalent proteins [PF18760.3, score=22.4]} {Human: ENSG00000107854, TNKS2, tankyrase 2, [Score=69.3, Expect=8e-13]; ENSG00000173273, TNKS, tankyrase, [Score=66.6, Expect=7e-12]; ENSG00000285372, AC270292.3, tankyrase, [Score=66.6, Expect=7e-12]} {Mouse: ENSMUSG00000024811, Tnks2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, [Score=68.9, Expect=9e-13]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=66.6, Expect=6e-12]} {Dmel: FBgn0027508, Tnks, tankyrase, [Score=69.3, Expect=5e-13]} {Celegans: WBGene00004049, parp-1, Poly(ADP-ribose) polymerase pme-1, [Score=66.2, Expect=1e-12]} {Smed: dd_Smed_v6_10338_0_1, dd_Smed_v6_10338_0_1, [Score=69.3, Expect=3e-13]} {RNA1509_52186} {RNA1310_24914.1} {RNA815_11069}

Mlig455_064398 {REF} {Length: 854} {Pfam: Poly(ADP-ribose) polymerase catalytic domain [PF00644.22, score=104.6]} {Human: ENSG00000107854, TNKS2, tankyrase 2, [Score=67.4, Expect=1e-12]; ENSG00000173273, TNKS, tankyrase, [Score=64.7, Expect=1e-11]; ENSG00000285372, AC270292.3, tankyrase, [Score=64.3, Expect=2e-11]} {Mouse: ENSMUSG00000024811, Tnks2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, [Score=66.6, Expect=2e-12]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=64.3, Expect=1e-11]} {Dmel: FBgn0027508, Tnks, tankyrase, [Score=67.8, Expect=7e-13]} {Celegans: WBGene00004049, parp-1, Poly(ADP-ribose) polymerase pme-1, [Score=65.5, Expect=8e-13]} {Smed: dd_Smed_v6_8547_0_1, dd_Smed_v6_8547_0_1, [Score=65.9, Expect=1e-12]} {RNA1509_52186} {RNA1310_24914.1} {RNA815_11069}
48. MligTC455_54747 11 0.22 Mlig455_034717

Neo: -

Age: -

 0.956 - - - - 0.956 - Mlig455_034717 {REF} {Length: 616} {Pfam: Inter-alpha-trypsin inhibitor heavy chain C-terminus [PF06668.14, score=20.8]}
49. MligTC455_04382 17 0.35 Mlig455_001234, Mlig455_034595

Neo: -

Age: -

 PCDH9 0.955 - - - - 0.955 -

Mlig455_001234 {REF} {Length: 2910} {Pfam: Cadherin domain [PF00028.19, score=196.4]; Cadherin-like [PF16184.7, score=46.1]; Bacterial cadherin-like domain [PF17803.3, score=26.8]} {Human: ENSG00000184226, PCDH9, protocadherin 9, [Score=195, Expect=1e-50]} {Mouse: ENSMUSG00000055421, Pcdh9, protocadherin 9, [Score=192, Expect=3e-50]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=183, Expect=1e-46]} {Dmel: FBgn0024836, stan, starry night, [Score=189, Expect=2e-48]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=140, Expect=2e-33]} {Smed: dd_Smed_v6_12697_0_1, dd_Smed_v6_12697_0_1, [Score=205, Expect=7e-55]} {RNA1310_103678}

Mlig455_034595 {REF} {Length: 4374} {Pfam: Cadherin domain [PF00028.19, score=226.9]; Cadherin-like [PF16184.7, score=45.7]; Bacterial cadherin-like domain [PF17803.3, score=26.8]} {Human: ENSG00000184226, PCDH9, protocadherin 9, [Score=204, Expect=3e-53]} {Mouse: ENSMUSG00000055421, Pcdh9, protocadherin 9, [Score=201, Expect=5e-52]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=197, Expect=1e-50]} {Dmel: FBgn0024836, stan, starry night, [Score=202, Expect=3e-52]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=137, Expect=2e-32]} {Smed: dd_Smed_v6_12697_0_1, dd_Smed_v6_12697_0_1, [RH, Score=229, Expect=3e-62]} {RNA1310_103678}
50. MligTC455_35730 22 0.47 Mlig455_068708

Neo: -

Age: -

 0.955 - - - - 0.955 - Mlig455_068708 {REF} {Length: 323} {NoTransDecoderORF} {RNA1310_109959}
51. MligTC455_13126 16 0.33 Mlig455_006139

Neo: -

Age: -

 0.953 - - - - 0.953 - Mlig455_006139 {REF} {Length: 2169} {NoTransDecoderORF} {RNA1509_46209} {RNA1310_76341} {RNA815_45428}
52. MligTC455_26366 75 1.56 Mlig455_013893

Neo: -

Age: -

 NSUN7 0.953 - - - - 0.953 - Mlig455_013893 {REF} {Length: 1904} {Human: ENSG00000179299, NSUN7, NOP2/Sun RNA methyltransferase family member 7, [Score=167, Expect=4e-45]} {Mouse: ENSMUSG00000029206, Nsun7, NOL1/NOP2/Sun domain family, member 7, [Score=164, Expect=3e-44]} {Dmel: FBgn0266099, CG44836, [Score=72.8, Expect=2e-13]} {Celegans: WBGene00013151, nsun-5, Nop2 (NOP2)/SUN domain family member, [Score=56.2, Expect=2e-08]} {Smed: dd_Smed_v6_30093_0_1, dd_Smed_v6_30093_0_1, [Score=203, Expect=3e-60]} {RNA1310_17601} {RNA815_32144}
53. MligTC455_30241 35 0.72 Mlig455_004299, Mlig455_006286, Mlig455_013663, Mlig455_013676

Neo: -

Age: -

 MAP3K19 0.953 - - - - 0.953 -

Mlig455_004299 {REF} {Length: 3294} {Pfam: Protein kinase domain [PF00069.27, score=193.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=146.7]; Ankyrin repeats (3 copies) [PF12796.9, score=76.6]; Ankyrin repeats (many copies) [PF13637.8, score=75.8]; Ankyrin repeats (many copies) [PF13857.8, score=51.4]; Ankyrin repeat [PF13606.8, score=35.7]; Fungal protein kinase [PF17667.3, score=30.8]; Ankyrin repeat [PF00023.32, score=30.6]; ABC1 atypical kinase-like domain [PF03109.18, score=20.7]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=155, Expect=7e-39]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=154, Expect=5e-40]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=138, Expect=4e-34]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=122, Expect=6e-29]} {Smed: dd_Smed_v6_1953_0_1, dd_Smed_v6_1953_0_1, [Score=129, Expect=8e-32]} {RNA1509_45037} {RNA1310_31580} {RNA815_5323.3}

Mlig455_006286 {REF} {Length: 1274} {Pfam: Protein kinase domain [PF00069.27, score=195.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=149.1]; Fungal protein kinase [PF17667.3, score=31.9]; ABC1 atypical kinase-like domain [PF03109.18, score=23.1]; Kinase-like [PF14531.8, score=19.2]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=150, Expect=1e-40]; ENSG00000180815, MAP3K15, mitogen-activated protein kinase kinase kinase 15, [Score=143, Expect=6e-37]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=150, Expect=1e-40]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=140, Expect=1e-36]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=123, Expect=6e-31]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=132, Expect=5e-34]} {RNA1509_45037} {RNA1310_22200.1} {RNA815_5323.2}

Mlig455_013663 {REF} {Length: 2891} {Pfam: Protein kinase domain [PF00069.27, score=177.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.7]; Ankyrin repeats (many copies) [PF13637.8, score=75.3]; Ankyrin repeats (3 copies) [PF12796.9, score=70.2]; Ankyrin repeats (many copies) [PF13857.8, score=52.2]; Ankyrin repeat [PF13606.8, score=32.6]; Fungal protein kinase [PF17667.3, score=30.4]; Ankyrin repeat [PF00023.32, score=27.4]; ABC1 atypical kinase-like domain [PF03109.18, score=20.4]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=136, Expect=1e-32]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=134, Expect=8e-33]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=119, Expect=2e-27]} {Celegans: WBGene00001121, dyf-5, Serine/threonine-protein kinase dyf-5, [Score=109, Expect=6e-25]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=120, Expect=9e-28]} {RNA1509_34593} {RNA1310_25002} {RNA815_5323.1}

Mlig455_013676 {REF} {Length: 3314} {Pfam: Protein kinase domain [PF00069.27, score=176.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.4]; Ankyrin repeats (many copies) [PF13637.8, score=76.4]; Ankyrin repeats (3 copies) [PF12796.9, score=71.0]; Ankyrin repeats (many copies) [PF13857.8, score=49.5]; Ankyrin repeat [PF13606.8, score=32.5]; Fungal protein kinase [PF17667.3, score=29.9]; Ankyrin repeat [PF00023.32, score=28.2]; ABC1 atypical kinase-like domain [PF03109.18, score=19.1]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=131, Expect=7e-31]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=130, Expect=2e-31]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=117, Expect=1e-26]} {Celegans: WBGene00001121, dyf-5, Serine/threonine-protein kinase dyf-5, [Score=110, Expect=3e-25]} {Smed: dd_Smed_v6_9984_0_1, dd_Smed_v6_9984_0_1, [Score=113, Expect=2e-27]} {RNA1509_34593} {RNA1310_25002} {RNA815_5323.1}
54. MligTC455_34192 134 2.8 Mlig455_022589

Neo: -

Age: -

 0.953 - - - - 0.953 - Mlig455_022589 {REF} {Length: 1896} {RNA1509_34101} {RNA1310_46799} {RNA815_22648}
55. MligTC455_50835 13 0.26 Mlig455_054685

Neo: -

Age: Up-Down-Up

 ANK2 0.953 - - - - 0.953 - Mlig455_054685 {REF} {Length: 4587} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=35.4]; Ankyrin repeats (many copies) [PF13637.8, score=29.9]; Ankyrin repeats (many copies) [PF13857.8, score=24.9]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=58.2, Expect=1e-07]; ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=57.4, Expect=2e-07]; ENSG00000151150, ANK3, ankyrin 3, [Score=55.5, Expect=7e-07]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=61.6, Expect=4e-09]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=67.8, Expect=6e-11]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=55.5, Expect=3e-07]} {Smed: dd_Smed_v6_13669_0_1, dd_Smed_v6_13669_0_1, [Score=77.8, Expect=3e-14]} {RNA1509_33286} {RNA1310_11240} {RNA815_17700}
56. MligTC455_04083 51 1.05 Mlig455_038343, Mlig455_038369, Mlig455_068288

Neo: -

Age: -

 0.952 - - - - 0.952 -

Mlig455_038343 {REF} {Length: 680} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=35.3]} {RNA1310_74189} {RNA815_45309}

Mlig455_038369 {REF} {Length: 2060} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=42.5]} {RNA1310_80577} {RNA815_45309}

Mlig455_068288 {REF} {Length: 2096} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=39.5]} {RNA1310_80577} {RNA815_45309}
57. MligTC455_37484 28 0.57 Mlig455_070675

Neo: -

Age: -

 0.952 - - - - 0.952 - Mlig455_070675 {REF} {Length: 3649} {RNA1310_7246} {RNA815_26161}
58. MligTC455_15475 25 0.51 Mlig455_001532

Neo: -

Age: -

 0.951 - - - - 0.951 - Mlig455_001532 {REF} {Length: 2000} {NoTransDecoderORF} {RNA1509_39091} {RNA1310_41102} {RNA815_50587}
59. MligTC455_28331 23 0.48 Mlig455_057516

Neo: -

Age: -

 0.951 - - - - 0.951 - Mlig455_057516 {REF} {Length: 1069} {RNA1509_52975} {RNA1310_45589} {RNA815_54554}
60. MligTC455_28339 104 2.17 Mlig455_055568

Neo: -

Age: logFC(26M/2M)=1.216

 ITCH 0.951 - - - - 0.951 - Mlig455_055568 {REF} {Length: 4696} {TRANSSPLICED} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=298.3]; WW domain [PF00397.28, score=92.0]; C2 domain [PF00168.32, score=40.0]} {Human: ENSG00000078747, ITCH, itchy E3 ubiquitin protein ligase, [Score=591, Expect=0.0]; ENSG00000198373, WWP2, WW domain containing E3 ubiquitin protein ligase 2, [Score=585, Expect=0.0]; ENSG00000123124, WWP1, WW domain containing E3 ubiquitin protein ligase 1, [Score=581, Expect=0.0]} {Mouse: ENSMUSG00000027598, Itch, itchy, E3 ubiquitin protein ligase, [Score=590, Expect=0.0]; ENSMUSG00000031930, Wwp2, WW domain containing E3 ubiquitin protein ligase 2, [Score=587, Expect=0.0]; ENSMUSG00000041058, Wwp1, WW domain containing E3 ubiquitin protein ligase 1, [Score=580, Expect=0.0]} {Dmel: FBgn0003557, Su(dx), Suppressor of deltex, [Score=553, Expect=0.0]} {Celegans: WBGene00007009, wwp-1, E3 ubiquitin-protein ligase, [Score=578, Expect=0.0]} {Smed: dd_Smed_v6_7779_0_1, dd_Smed_v6_7779_0_1, [Score=573, Expect=0.0]} {RNA1509_12682} {RNA1310_9181, RNA1509_12682} {RNA1509_12682, RNA815_13641}
61. MligTC455_44476 9 0.19 Mlig455_034320

Neo: -

Age: -

 LRRC4 0.951 - - - - 0.951 - Mlig455_034320 {REF} {Length: 3577} {Pfam: Leucine rich repeat [PF13855.8, score=54.1]; Immunoglobulin domain [PF13927.8, score=43.0]; Immunoglobulin I-set domain [PF07679.18, score=33.8]; Immunoglobulin domain [PF13895.8, score=31.8]; Immunoglobulin domain [PF00047.27, score=25.2]; Immunoglobulin V-set domain [PF07686.19, score=23.9]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=23.9]} {Human: ENSG00000128594, LRRC4, leucine rich repeat containing 4, [Score=80.9, Expect=2e-15]; ENSG00000101825, MXRA5, matrix remodeling associated 5, [Score=80.1, Expect=9e-15]} {Mouse: ENSMUSG00000049939, Lrrc4, leucine rich repeat containing 4, [Score=80.9, Expect=2e-15]} {Dmel: FBgn0015399, kek1, kekkon-1, [RH, Score=93.2, Expect=3e-19]} {Celegans: WBGene00004854, slt-1, Slit homolog 1 protein, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_18031_0_1, dd_Smed_v6_18031_0_1, [Score=140, Expect=8e-35]} {RNA1310_61519} {RNA815_32750}
62. MligTC455_16586 410 8.55 Mlig455_059353, Mlig455_065581

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.614

 0.95 - - - - 0.950 -

Mlig455_059353 {REF} {Length: 2125} {TRANSSPLICED} {RNA1310_49327}

Mlig455_065581 {REF} {Length: 2122} {TRANSSPLICED} {RNA1310_49327}
63. MligTC455_22091 16 0.33 Mlig455_007206

Neo: -

Age: -

 PRR9 0.95 - - - - 0.950 - Mlig455_007206 {REF} {Length: 2075} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=50.8, Expect=1e-07]} {RNA1310_45787}
64. MligTC455_26833 22 0.46 Mlig455_048301

Neo: -

Age: -

 OPLAH 0.95 - - - - 0.950 - Mlig455_048301 {REF} {Length: 4436} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=626.3]; Hydantoinase/oxoprolinase [PF01968.20, score=350.5]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=203.7]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=36.1]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [RH, Score=1454, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [RH, Score=1424, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [RH, Score=1391, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [RH, Score=1409, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=989, Expect=0.0]} {RNA1509_2948, RNA1509_37889} {RNA1310_1508.1, RNA1509_37889} {RNA1509_37889, RNA815_468}
65. MligTC455_33156 242 5.04 Mlig455_009077

Neo: -

Age: -

 0.95 - - - - 0.950 - Mlig455_009077 {REF} {Length: 1532} {RNA1509_51204} {RNA1310_20216} {RNA815_16273.1}
66. MligTC455_33158 236 4.92 Mlig455_058103

Neo: -

Age: -

 0.95 - - - - 0.950 - Mlig455_058103 {REF} {Length: 2616} {RNA1509_51204} {RNA1310_18006.1} {RNA815_6624}
67. MligTC455_35444 12 0.25 Mlig455_052986

Neo: -

Age: -

 0.95 - - - - 0.950 - Mlig455_052986 {REF} {Length: 637} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=79.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=45.4]} {Smed: dd_Smed_v6_18197_0_1, dd_Smed_v6_18197_0_1, [Score=75.9, Expect=9e-20]} {RNA1310_832} {RNA815_5321.2}
68. MligTC455_43366 86 1.79 Mlig455_055680

Neo: -

Age: logFC(26M/2M)=1.002

 TNN 0.95 - - - - 0.950 - Mlig455_055680 {REF} {Length: 2991} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=110.9]} {Human: ENSG00000120332, TNN, tenascin N, [Score=97.4, Expect=4e-22]; ENSG00000166482, MFAP4, microfibril associated protein 4, [Score=93.2, Expect=1e-21]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=95.9, Expect=1e-21]; ENSMUSG00000033327, Tnxb, tenascin XB, [Score=92.0, Expect=2e-20]} {Dmel: FBgn0003326, sca, scabrous, [Score=82.4, Expect=2e-17]} {Celegans: WBGene00020516, T15B7.1, [Score=52.4, Expect=1e-07]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=43.5, Expect=1e-05]} {RNA1509_25852} {RNA1310_16471.3} {RNA815_7229.1}

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