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Results for MligTC455_30458

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_30458 451 9.39 Mlig455_062993

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.026

FTCD Mlig455_062993 {REF} {Length: 2008} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=187.7]; Formiminotransferase domain [PF02971.16, score=179.9]; Formiminotransferase-cyclodeaminase [PF04961.14, score=66.0]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [Score=400, Expect=9e-135]; ENSG00000281775, FTCD, formimidoyltransferase cyclodeaminase, [Score=399, Expect=6e-136]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [Score=402, Expect=7e-136]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [Score=292, Expect=3e-93]} {RNA1509_29292} {RNA1310_13312} {RNA815_5334}

Cumulative graph for MligTC455_30458

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.159 3.443 0.93446 1.00000
RegionR2 0.295 3.443 0.62668 0.96839
RegionR3 0.79 3.443 0.08993 0.52959
RegionR4 0.002 3.443 0.98953 1.00000
RegionR5 -1.259 3.443 0.04722 0.18005
RegionR6 -0.168 3.443 0.76716 1.00000
RegionR7 0.332 3.443 0.63799 1.00000
RegionR8 0.166 3.443 0.86399 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.651 3.443 0.77815 1.00000
RegenerationR2 0.165 3.443 0.71121 0.96036
RegenerationR3 -0.23 3.443 0.62976 0.92022
RegenerationR4 0.827 3.443 0.12863 0.54329
RegenerationR5 1.076 3.443 0.04416 0.34442
RegenerationR6 0.253 3.443 0.64243 0.89447
RegenerationBL 0.171 3.443 0.79540 1.00000
RegenerationTP 0.422 3.443 0.55596 0.93690


Genes with expression patterns similar to MligTC455_30458

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_30458 451 9.39 Mlig455_062993

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.026

FTCD 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_062993 {REF} {Length: 2008} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=187.7]; Formiminotransferase domain [PF02971.16, score=179.9]; Formiminotransferase-cyclodeaminase [PF04961.14, score=66.0]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [Score=400, Expect=9e-135]; ENSG00000281775, FTCD, formimidoyltransferase cyclodeaminase, [Score=399, Expect=6e-136]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [Score=402, Expect=7e-136]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [Score=292, Expect=3e-93]} {RNA1509_29292} {RNA1310_13312} {RNA815_5334}
2. MligTC455_30457 489 10.18 Mlig455_051232

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.520

FTCD 5.893 0.990 0.952 0.975 0.999 0.994 0.983 Mlig455_051232 {REF} {Length: 3312} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=229.8]; Formiminotransferase domain [PF02971.16, score=200.9]; Formiminotransferase-cyclodeaminase [PF04961.14, score=176.4]; SAP domain [PF02037.29, score=32.2]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [RH, Score=571, Expect=0.0]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [RH, Score=571, Expect=0.0]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [RH, Score=398, Expect=1e-127]} {RNA1509_29292} {RNA1310_13312} {RNA815_5334}
3. MligTC455_30456 610 12.7 Mlig455_032197, Mlig455_051152

Neo: -

Age: Down-Down-Up

FTCD 3.5 0.970 0.921 - - 0.850 0.759

Mlig455_032197 {REF} {Length: 1829} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=233.8]; Formiminotransferase domain [PF02971.16, score=198.1]; Formiminotransferase-cyclodeaminase [PF04961.14, score=177.4]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [RH, Score=562, Expect=0.0]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [RH, Score=570, Expect=0.0]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [RH, Score=399, Expect=2e-133]} {RNA1509_51900} {RNA1310_13312} {RNA815_5334}

Mlig455_051152 {REF} {Length: 2137} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=233.7]; Formiminotransferase domain [PF02971.16, score=198.1]; Formiminotransferase-cyclodeaminase [PF04961.14, score=177.3]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [RH, Score=563, Expect=0.0]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [RH, Score=571, Expect=0.0]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [RH, Score=400, Expect=2e-134]} {RNA1509_29292} {RNA1310_13312} {RNA815_5334}
4. MligTC455_31981 341 7.11 Mlig455_020923

Neo: -

Age: -

DIS3L2 2.653 - - - 0.982 0.840 0.831 Mlig455_020923 {REF} {Length: 724} {Pfam: DIS3-like exonuclease 2 C terminal [PF17877.3, score=42.2]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=50.8, Expect=7e-08]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=53.1, Expect=2e-08]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=49.7, Expect=2e-07]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=68.9, Expect=3e-14]} {RNA1509_57497} {RNA1310_4374.3} {RNA815_1234.1}
5. MligTC455_31982 348 7.25 Mlig455_020999

Neo: -

Age: -

DIS3L2 2.648 - - - 0.983 0.842 0.823 Mlig455_020999 {REF} {Length: 2751} {TRANSSPLICED} {Pfam: RNB domain [PF00773.21, score=279.9]; DIS3-like exonuclease 2 C terminal [PF17877.3, score=36.6]; Rrp44-like cold shock domain [PF17216.5, score=27.4]; Dis3-like cold-shock domain 2 (CSD2) [PF17849.3, score=23.3]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=358, Expect=3e-110]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=366, Expect=1e-113]} {Dmel: FBgn0035111, Dis3l2, Dis3 like 3'-5' exoribonuclease 2, [Score=254, Expect=2e-71]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=325, Expect=8e-99]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=344, Expect=5e-106]} {RNA1509_57497} {RNA1310_4374.3} {RNA815_1234.1}
6. MligTC455_37471 494 10.29 Mlig455_067139

Neo: -

Age: -

2.605 - - - 0.964 0.883 0.758 Mlig455_067139 {REF} {Length: 3223} {Pfam: Polymer-forming cytoskeletal [PF04519.15, score=36.7]} {RNA1509_58187} {RNA1310_57569} {RNA815_25125}
7. MligTC455_50326 349 7.27 Mlig455_000563, Mlig455_030362

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.949/0.00096

ARID3A 2.528 - - - 0.951 0.870 0.707

Mlig455_000563 {REF} {Length: 2916} {Pfam: ARID/BRIGHT DNA binding domain [PF01388.23, score=72.3]} {Human: ENSG00000116017, ARID3A, AT-rich interaction domain 3A, [RH, Score=244, Expect=4e-74]; ENSG00000205143, ARID3C, AT-rich interaction domain 3C, [RH, Score=244, Expect=5e-73]; ENSG00000179361, ARID3B, AT-rich interaction domain 3B, [RH, Score=236, Expect=3e-68]} {Mouse: ENSMUSG00000019564, Arid3a, AT rich interactive domain 3A (BRIGHT-like), [RH, Score=247, Expect=3e-72]; ENSMUSG00000066224, Arid3c, AT rich interactive domain 3C (BRIGHT-like), [RH, Score=247, Expect=2e-74]; ENSMUSG00000004661, Arid3b, AT rich interactive domain 3B (BRIGHT-like), [RH, Score=235, Expect=4e-68]} {Dmel: FBgn0004795, retn, retained, [RH, Score=244, Expect=7e-69]} {Celegans: WBGene00000476, cfi-1, AT-rich interactive domain-containing protein cfi-1, [RH, Score=229, Expect=6e-67]} {Smed: dd_Smed_v6_13474_0_1, dd_Smed_v6_13474_0_1, [RH, Score=257, Expect=3e-76]} {RNA1310_43081} {RNA815_22524}

Mlig455_030362 {REF} {Length: 2929} {Pfam: ARID/BRIGHT DNA binding domain [PF01388.23, score=72.3]} {Human: ENSG00000116017, ARID3A, AT-rich interaction domain 3A, [RH, Score=241, Expect=9e-73]; ENSG00000205143, ARID3C, AT-rich interaction domain 3C, [RH, Score=241, Expect=6e-72]; ENSG00000179361, ARID3B, AT-rich interaction domain 3B, [RH, Score=233, Expect=4e-67]} {Mouse: ENSMUSG00000066224, Arid3c, AT rich interactive domain 3C (BRIGHT-like), [RH, Score=244, Expect=1e-73]; ENSMUSG00000019564, Arid3a, AT rich interactive domain 3A (BRIGHT-like), [RH, Score=243, Expect=7e-71]; ENSMUSG00000004661, Arid3b, AT rich interactive domain 3B (BRIGHT-like), [RH, Score=232, Expect=6e-67]} {Dmel: FBgn0004795, retn, retained, [RH, Score=240, Expect=1e-67]} {Celegans: WBGene00000476, cfi-1, AT-rich interactive domain-containing protein cfi-1, [RH, Score=229, Expect=5e-67]} {Smed: dd_Smed_v6_13474_0_1, dd_Smed_v6_13474_0_1, [RH, Score=258, Expect=2e-76]} {RNA1310_43081} {RNA815_22524}
8. MligTC455_51092 610 12.7 Mlig455_023059

Neo: -

Age: logFC(26M/2M)=-0.406

HMCN1 2.526 - - - 0.960 0.789 0.777 Mlig455_023059 {REF} {Length: 4021} {Pfam: Fibronectin type II domain [PF00040.21, score=49.5]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=97.4, Expect=1e-19]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=100, Expect=6e-21]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=65.5, Expect=2e-10]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [Score=71.2, Expect=3e-12]} {Smed: dd_Smed_v6_14729_0_1, dd_Smed_v6_14729_0_1, [Score=113, Expect=2e-26]} {RNA1509_31155, RNA1509_9903} {RNA1310_3672.1, RNA1509_31155, RNA1509_9903} {RNA1509_31155, RNA1509_9903, RNA815_6438}
9. MligTC455_34010 204 4.26 Mlig455_024028, Mlig455_024093

Neo: -

Age: Up-Down-Down

KCNC1 2.512 0.726 - - 0.981 - 0.805

Mlig455_024028 {REF} {Length: 3896} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734}

Mlig455_024093 {REF} {Length: 3992} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734}
10. MligTC455_16991 437 9.09 Mlig455_057989

Neo: -

Age: Up-Up-Down

Regeneration-downregulated BL: -7.705

Regeneration-depleted BL: -7.705

2.51 0.802 - - 0.983 - 0.725 Mlig455_057989 {REF} {Length: 4840} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=124.1]; WSC domain [PF01822.21, score=40.4]} {Celegans: WBGene00003168, mec-4, Degenerin mec-4, [Score=64.3, Expect=3e-10]} {Smed: dd_Smed_v6_15195_0_1, dd_Smed_v6_15195_0_1, [Score=65.1, Expect=1e-10]} {RNA1509_20328} {RNA1310_3478} {RNA815_19382.2}
11. MligTC455_18654 497 10.36 Mlig455_032693

Neo: -

Age: -

PPME1 2.499 0.767 - - 0.966 0.766 - Mlig455_032693 {REF} {Length: 2557} {TRANSSPLICED} {Pfam: Alpha/beta hydrolase family [PF12697.9, score=84.1]; alpha/beta hydrolase fold [PF00561.22, score=34.3]; Serine aminopeptidase, S33 [PF12146.10, score=30.6]; alpha/beta hydrolase fold [PF07859.15, score=20.5]; PGAP1-like protein [PF07819.15, score=19.9]} {Human: ENSG00000214517, PPME1, protein phosphatase methylesterase 1, [RH, Score=273, Expect=6e-87]} {Mouse: ENSMUSG00000030718, Ppme1, protein phosphatase methylesterase 1, [RH, Score=157, Expect=3e-43]} {Dmel: FBgn0035951, CG5068, [RH, Score=262, Expect=6e-83]} {Celegans: WBGene00007188, B0464.9, Probable protein phosphatase methylesterase 1, [RH, Score=147, Expect=4e-40]} {Smed: dd_Smed_v6_5813_0_1, dd_Smed_v6_5813_0_1, [RH, Score=291, Expect=1e-94]} {RNA1509_18678, RNA1509_50525} {RNA1310_14476, RNA1509_50525} {RNA1509_50525, RNA815_3742.1}
12. MligTC455_15600 488 10.17 Mlig455_045950

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.255/0.03614

NUDT2 2.477 - - - 0.972 0.795 0.710 Mlig455_045950 {REF} {Length: 760} {TRANSSPLICED} {Pfam: NUDIX domain [PF00293.30, score=65.2]} {Human: ENSG00000164978, NUDT2, nudix hydrolase 2, [RH, Score=114, Expect=8e-33]} {Mouse: ENSMUSG00000028443, Nudt2, nudix (nucleoside diphosphate linked moiety X)-type motif 2, [RH, Score=112, Expect=5e-32]} {Dmel: FBgn0051713, Apf, diadenosine tetraphosphate hydrolase, [RH, Score=97.8, Expect=2e-26]} {Celegans: WBGene00003581, ndx-4, Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], [RH, Score=107, Expect=1e-30]} {RNA1509_18921} {RNA1310_32852.2} {RNA815_24705}
13. MligTC455_42273 272 5.67 Mlig455_039400

Neo: -

Age: Up-Down-Down

Region-enriched R8: 6.215/0.00000

RASGRF1 2.476 - 0.711 - 0.965 - 0.800 Mlig455_039400 {REF} {Length: 5341} {Pfam: RasGEF domain [PF00617.21, score=186.0]; RhoGEF domain [PF00621.22, score=114.0]; PH domain [PF00169.31, score=70.4]; RasGEF N-terminal motif [PF00618.22, score=67.2]; Pleckstrin homology domain [PF15413.8, score=23.5]} {Human: ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [RH, Score=752, Expect=0.0]; ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [RH, Score=741, Expect=0.0]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=153, Expect=5e-37]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=115, Expect=1e-25]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [RH, Score=1133, Expect=0.0]} {RNA1509_54715} {RNA1310_10415, RNA1509_54715} {RNA1509_54715, RNA815_14434}
14. MligTC455_07087 753 15.69 Mlig455_033003, Mlig455_044987, Mlig455_044989, Mlig455_052687

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.952

2.462 - - 0.763 0.978 0.721 -

Mlig455_033003 {REF} {Length: 253} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}

Mlig455_044987 {REF} {Length: 249} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944, RNA1509_51459} {RNA1509_51459, RNA815_10907}

Mlig455_044989 {REF} {Length: 239} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}

Mlig455_052687 {REF} {Length: 243} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}
15. MligTC455_15625 959 19.99 Mlig455_004634

Neo: -

Age: -

EI24 2.424 - - 0.702 0.984 0.738 - Mlig455_004634 {REF} {Length: 2071} {TRANSSPLICED} {Pfam: Etoposide-induced protein 2.4 (EI24) [PF07264.13, score=56.2]} {Human: ENSG00000149547, EI24, EI24, autophagy associated transmembrane protein, [RH, Score=146, Expect=1e-40]} {Mouse: ENSMUSG00000062762, Ei24, etoposide induced 2.4 mRNA, [RH, Score=144, Expect=6e-40]} {Dmel: FBgn0031635, tank, [RH, Score=119, Expect=7e-30]} {Celegans: WBGene00018150, epg-4, Ectopic P granules protein 4, [RH, Score=80.9, Expect=3e-17]} {RNA1509_6364} {RNA1310_14599, RNA1509_6364} {RNA1509_6364, RNA815_5331}
16. MligTC455_46400 754 15.71 Mlig455_009563

Neo: -

Age: -

MAP3K12 2.411 - - - 0.977 0.715 0.719 Mlig455_009563 {REF} {Length: 3805} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=179.7]; Protein kinase domain [PF00069.27, score=158.8]} {Human: ENSG00000139625, MAP3K12, mitogen-activated protein kinase kinase kinase 12, [RH, Score=290, Expect=9e-84]} {Mouse: ENSMUSG00000023050, Map3k12, mitogen-activated protein kinase kinase kinase 12, [RH, Score=290, Expect=1e-83]} {Dmel: FBgn0036896, wnd, wallenda, [RH, Score=263, Expect=6e-74]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [Score=233, Expect=3e-66]} {Smed: dd_Smed_v6_8838_0_1, dd_Smed_v6_8838_0_1, [RH, Score=237, Expect=5e-65]} {RNA1509_42265, RNA1509_56503, RNA1509_8182} {RNA1310_2912, RNA1509_42265, RNA1509_56503, RNA1509_8182} {RNA1509_42265, RNA1509_56503, RNA1509_8182, RNA815_3381.1}
17. MligTC455_37160 1139 23.73 Mlig455_015317, Mlig455_032998, Mlig455_068744

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R2: 1.560/0.01222

TTC28 1.924 0.942 - - 0.982 - -

Mlig455_015317 {REF} {Length: 5958} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=63.4]; Tetratricopeptide repeat [PF07719.19, score=51.3]; Tetratricopeptide repeat [PF00515.30, score=40.4]; Tetratricopeptide repeat [PF13181.8, score=39.5]; CHAT domain [PF12770.9, score=37.9]; Tetratricopeptide repeat [PF14559.8, score=23.5]; Tetratricopeptide repeat [PF13431.8, score=22.4]; Tetratricopeptide repeat [PF13176.8, score=20.4]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=7e-11]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=70.9, Expect=2e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_032998 {REF} {Length: 5728} {Pfam: CHAT domain [PF12770.9, score=39.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=3e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_068744 {REF} {Length: 5980} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=62.6]; Tetratricopeptide repeat [PF07719.19, score=49.0]; Tetratricopeptide repeat [PF13181.8, score=39.3]; Tetratricopeptide repeat [PF00515.30, score=38.4]; CHAT domain [PF12770.9, score=37.8]; Tetratricopeptide repeat [PF14559.8, score=22.1]; Tetratricopeptide repeat [PF13431.8, score=20.8]; Tetratricopeptide repeat [PF13176.8, score=19.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=66.2, Expect=6e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {RNA1509_5411} {RNA1310_761.2} {RNA815_600}
18. MligTC455_16902 287 5.97 Mlig455_030566

Neo: -

Age: -

NETO2 1.907 0.955 - - 0.952 - - Mlig455_030566 {REF} {Length: 3702} {Pfam: CUB domain [PF00431.22, score=70.2]; Low-density lipoprotein receptor domain class A [PF00057.20, score=34.0]} {Human: ENSG00000171208, NETO2, neuropilin and tolloid like 2, [Score=130, Expect=3e-31]} {Mouse: ENSMUSG00000036902, Neto2, neuropilin (NRP) and tolloid (TLL)-like 2, [Score=129, Expect=5e-31]} {Dmel: FBgn0265416, Neto, Neuropilin and tolloid-like, [Score=118, Expect=5e-27]} {Celegans: WBGene00019360, neto-1, NETO (NEuropilin and TOlloid-like) homolog, [RH, Score=125, Expect=4e-31]} {Smed: dd_Smed_v6_8579_0_1, dd_Smed_v6_8579_0_1, [RH, Score=143, Expect=2e-35]} {RNA1509_23788, RNA1509_52170} {RNA1310_3313, RNA1509_23788, RNA1509_52170} {RNA1509_23788, RNA1509_52170, RNA815_7210}
19. MligTC455_29193 967 20.15 Mlig455_018315, Mlig455_061014, Mlig455_067207

Neo: -

Age: Down-Down-Up

1.897 0.934 - - 0.963 - -

Mlig455_018315 {REF} {Length: 2676} {TRANSSPLICED} {RNA1509_52931} {RNA1310_28021} {RNA815_28552}

Mlig455_061014 {REF} {Length: 2001} {RNA1310_29654.1} {RNA815_17301.1}

Mlig455_067207 {REF} {Length: 584} {TRANSSPLICED} {RNA1310_29654.1} {RNA815_17301.1}
20. MligTC455_44648 177 3.69 Mlig455_013655

Neo: -

Age: -

1.887 0.916 - - 0.971 - - Mlig455_013655 {REF} {Length: 2045} {Pfam: Protein kinase domain [PF00069.27, score=24.6]} {RNA1509_54731} {RNA1310_1875.2} {RNA815_820}
21. MligTC455_26666 497 10.35 Mlig455_014576

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.303

CNBD2 1.884 0.911 - - 0.973 - - Mlig455_014576 {REF} {Length: 3147} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=74.1]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [RH, Score=97.8, Expect=2e-20]} {Mouse: ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [RH, Score=86.3, Expect=3e-17]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=58.2, Expect=9e-09]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=62.0, Expect=5e-10]} {Smed: dd_Smed_v6_15589_0_1, dd_Smed_v6_15589_0_1, [RH, Score=451, Expect=2e-148]} {RNA1509_14495, RNA1509_43806} {RNA1310_6298, RNA1509_43806} {RNA1509_43806, RNA815_2010}
22. MligTC455_44341 241 5.03 Mlig455_004553

Neo: -

Age: -

SENP8 1.862 0.885 - - 0.977 - - Mlig455_004553 {REF} {Length: 1090} {Pfam: Ulp1 protease family, C-terminal catalytic domain [PF02902.21, score=31.5]} {Human: ENSG00000166192, SENP8, SUMO peptidase family member, NEDD8 specific, [Score=50.1, Expect=3e-07]} {Mouse: ENSMUSG00000051705, Senp8, SUMO/sentrin specific peptidase 8, [Score=47.4, Expect=2e-06]} {RNA1509_41235} {RNA1310_35410} {RNA815_32992}
23. MligTC455_40998 202 4.21 Mlig455_030227, Mlig455_068004

Neo: -

Age: Down-Up-Up

PRG4 1.859 0.895 - - 0.964 - -

Mlig455_030227 {REF} {Length: 1061} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [Score=63.9, Expect=8e-11]} {RNA1310_70482}

Mlig455_068004 {REF} {Length: 1488} {Human: ENSG00000116690, PRG4, proteoglycan 4, [RH, Score=55.1, Expect=2e-07]} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [RH, Score=70.5, Expect=1e-12]} {Dmel: FBgn0052656, Muc11A, Mucin 11A, [Score=56.2, Expect=3e-08]} {RNA1310_70482}
24. MligTC455_43329 235 4.9 Mlig455_007154

Neo: -

Age: -

Region-enriched R2: 3.268/0.02528
Region-enriched R5: 2.289/0.03532

SMURF2 1.857 0.883 - - 0.974 - - Mlig455_007154 {REF} {Length: 4687} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=303.1]; WW domain [PF00397.28, score=64.2]} {Human: ENSG00000108854, SMURF2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000018363, Smurf2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0259174, Nedd4, [Score=409, Expect=4e-133]} {Celegans: WBGene00022358, Y92H12A.2, E3 ubiquitin-protein ligase, [Score=400, Expect=2e-133]} {Smed: dd_Smed_v6_7322_0_1, dd_Smed_v6_7322_0_1, [Score=398, Expect=2e-128]} {RNA1509_42014} {RNA1310_6371} {RNA815_17584}
25. MligTC455_15895 226 4.71 Mlig455_064442

Neo: -

Age: Down-Up-Up

RABGGTB 1.853 - - - 0.973 0.880 - Mlig455_064442 {REF} {Length: 1470} {TRANSSPLICED} {Pfam: Prenyltransferase and squalene oxidase repeat [PF00432.23, score=184.4]; Squalene-hopene cyclase N-terminal domain [PF13249.8, score=19.3]} {Human: ENSG00000137955, RABGGTB, Rab geranylgeranyltransferase subunit beta, [RH, Score=384, Expect=2e-133]} {Mouse: ENSMUSG00000038975, Rabggtb, Rab geranylgeranyl transferase, b subunit, [RH, Score=374, Expect=9e-130]} {Dmel: FBgn0028970, betaggt-II, beta subunit of type II geranylgeranyl transferase, [RH, Score=362, Expect=5e-125]} {Celegans: WBGene00015099, ggtb-1, Probable geranylgeranyl transferase type-2 subunit beta, [RH, Score=364, Expect=7e-126]} {Smed: dd_Smed_v6_3769_0_1, dd_Smed_v6_3769_0_1, [RH, Score=343, Expect=1e-117]} {RNA1509_27970} {RNA1310_22063, RNA1509_27970} {RNA1509_27970, RNA815_29569}
26. MligTC455_41222 503 10.48 Mlig455_008819, Mlig455_008917

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 2.661/0.00033

UBE2T 1.852 0.878 - - 0.974 - -

Mlig455_008819 {REF} {Length: 1153} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=127.8]} {Human: ENSG00000077152, UBE2T, ubiquitin conjugating enzyme E2 T, [RH, Score=166, Expect=2e-51]} {Mouse: ENSMUSG00000026429, Ube2t, ubiquitin-conjugating enzyme E2T, [RH, Score=149, Expect=4e-45]} {Dmel: FBgn0000173, ben, bendless, [Score=129, Expect=4e-38]} {Celegans: WBGene00006708, ubc-13, Ubiquitin-conjugating enzyme E2 13, [Score=134, Expect=7e-40]} {Smed: dd_Smed_v6_1075_0_1, dd_Smed_v6_1075_0_1, [Score=130, Expect=1e-38]} {RNA1509_29240} {RNA1310_31665} {RNA815_39037}

Mlig455_008917 {REF} {Length: 1154} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=127.8]} {Human: ENSG00000077152, UBE2T, ubiquitin conjugating enzyme E2 T, [RH, Score=166, Expect=2e-51]} {Mouse: ENSMUSG00000026429, Ube2t, ubiquitin-conjugating enzyme E2T, [RH, Score=149, Expect=4e-45]} {Dmel: FBgn0000173, ben, bendless, [Score=129, Expect=4e-38]} {Celegans: WBGene00006708, ubc-13, Ubiquitin-conjugating enzyme E2 13, [Score=134, Expect=7e-40]} {Smed: dd_Smed_v6_1075_0_1, dd_Smed_v6_1075_0_1, [Score=130, Expect=1e-38]} {RNA1509_29240} {RNA1310_31665} {RNA815_39037}
27. MligTC455_16863 349 7.26 Mlig455_009275

Neo: -

Age: Down-Up-Down

DYRK1B 1.843 0.864 - - 0.979 - - Mlig455_009275 {REF} {Length: 5761} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=162.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.6]} {Human: ENSG00000281320, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000105204, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000157540, DYRK1A, dual specificity tyrosine phosphorylation regulated kinase 1A, [Score=469, Expect=1e-157]} {Mouse: ENSMUSG00000002409, Dyrk1b, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b, [Score=480, Expect=3e-162]; ENSMUSG00000022897, Dyrk1a, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a, [Score=470, Expect=5e-158]} {Dmel: FBgn0259168, mnb, minibrain, [Score=495, Expect=1e-169]} {Celegans: WBGene00003149, mbk-1, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1, [Score=431, Expect=3e-141]} {Smed: dd_Smed_v6_3773_0_1, dd_Smed_v6_3773_0_1, [Score=425, Expect=3e-136]} {RNA1509_9464} {RNA1310_10341} {RNA815_7238.1}
28. MligTC455_53544 626 13.04 Mlig455_025841

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.481

HEYL 1.842 0.887 - - 0.955 - - Mlig455_025841 {REF} {Length: 2716} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=42.7]} {Human: ENSG00000163909, HEYL, hes related family bHLH transcription factor with YRPW motif-like, [Score=57.4, Expect=3e-08]; ENSG00000135547, HEY2, hes related family bHLH transcription factor with YRPW motif 2, [Score=55.1, Expect=1e-07]; ENSG00000187821, HELT, helt bHLH transcription factor, [Score=55.1, Expect=1e-07]} {Mouse: ENSMUSG00000032744, Heyl, hairy/enhancer-of-split related with YRPW motif-like, [Score=56.6, Expect=4e-08]; ENSMUSG00000047171, Helt, helt bHLH transcription factor, [Score=55.1, Expect=7e-08]; ENSMUSG00000019789, Hey2, hairy/enhancer-of-split related with YRPW motif 2, [Score=54.7, Expect=2e-07]} {Dmel: FBgn0259938, cwo, clockwork orange, [Score=63.5, Expect=4e-10]} {Celegans: WBGene00015646, mlt-10, [RH, Score=176, Expect=2e-46]} {Smed: dd_Smed_v6_22479_0_1, dd_Smed_v6_22479_0_1, [Score=51.2, Expect=9e-07]} {RNA1509_49122} {RNA1310_18992.1} {RNA815_16883}
29. MligTC455_39920 1142 23.8 Mlig455_011422, Mlig455_061154, Mlig455_061165

Neo: -

Age: -

Region-enriched R2: 1.769/0.00399

1.833 - - - 0.975 0.858 -

Mlig455_011422 {REF} {Length: 1977} {TRANSSPLICED} {RNA1509_13930, RNA1509_46569} {RNA1310_5501, RNA1509_13930, RNA1509_46569} {RNA1509_13930, RNA1509_46569, RNA815_7475.1}

Mlig455_061154 {REF} {Length: 1127} {RNA1509_46569} {RNA1310_16826} {RNA815_7475.1}

Mlig455_061165 {REF} {Length: 1979} {RNA1509_46569} {RNA1310_5501} {RNA815_7475.1}
30. MligTC455_35664 1772 36.91 Mlig455_020393, Mlig455_028392, Mlig455_058437

Neo: -

Age: logFC(26M/2M)=-0.217

Region-enriched R4: 1.033/0.04115

CLHC1 1.826 - - - 0.968 0.858 -

Mlig455_020393 {REF} {Length: 1999} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.3]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [RH, Score=155, Expect=8e-40]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [RH, Score=160, Expect=8e-42]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=51.2, Expect=2e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [RH, Score=145, Expect=4e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_028392 {REF} {Length: 1994} {TRANSSPLICED} {Pfam: Clathrin-H-link [PF13838.8, score=35.7]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=110, Expect=4e-25]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [Score=54.7, Expect=3e-07]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.4, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=114, Expect=1e-26]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_058437 {REF} {Length: 2088} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.4]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=153, Expect=3e-39]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [Score=158, Expect=4e-41]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.8, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=144, Expect=9e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}
31. MligTC455_14762 717 14.94 Mlig455_029494

Neo: -

Age: -

1.824 - - - 0.983 0.841 - Mlig455_029494 {REF} {Length: 2696} {RNA1509_7935} {RNA1310_12227, RNA1509_7935} {RNA1509_7935, RNA815_4249}
32. MligTC455_12731 331 6.89 Mlig455_005108

Neo: -

Age: -

Region-enriched R6: 3.150/0.01756

1.816 0.842 - - 0.974 - - Mlig455_005108 {REF} {Length: 654} {NoTransDecoderORF} {RNA1509_44841} {RNA1310_66981} {RNA815_54535}
33. MligTC455_19737 936 19.49 Mlig455_001707

Neo: -

Age: -

1.816 0.847 - - 0.969 - - Mlig455_001707 {REF} {Length: 1748} {TRANSSPLICED} {Pfam: Mucin-like [PF16058.7, score=34.2]} {Smed: dd_Smed_v6_3936_0_1, dd_Smed_v6_3936_0_1, [Score=102, Expect=4e-24]} {RNA1509_50300} {RNA1310_14121} {RNA815_5699.1}
34. MligTC455_37124 221 4.61 Mlig455_015377

Neo: -

Age: Up-Down-Up

TPH1 1.815 - - - 0.982 0.833 - Mlig455_015377 {REF} {Length: 2026} {Pfam: Biopterin-dependent aromatic amino acid hydroxylase [PF00351.23, score=465.4]} {Human: ENSG00000129167, TPH1, tryptophan hydroxylase 1, [Score=400, Expect=8e-136]; ENSG00000139287, TPH2, tryptophan hydroxylase 2, [Score=390, Expect=4e-131]} {Mouse: ENSMUSG00000040046, Tph1, tryptophan hydroxylase 1, [Score=402, Expect=1e-136]; ENSMUSG00000006764, Tph2, tryptophan hydroxylase 2, [Score=389, Expect=3e-131]} {Dmel: FBgn0035187, Trh, trachealess, [Score=375, Expect=1e-124]} {Celegans: WBGene00006600, tph-1, TryPtophan Hydroxylase; Tryptophan hydroxylase, [Score=353, Expect=6e-118]} {Smed: dd_Smed_v6_8392_0_2, dd_Smed_v6_8392_0_2, [Score=408, Expect=4e-138]} {RNA1310_18054} {RNA815_7494}
35. MligTC455_07206 105 2.19 Mlig455_032806

Neo: -

Age: -

1.814 - - - 0.974 0.840 - Mlig455_032806 {REF} {Length: 618} {NoTransDecoderORF} {RNA1310_136285}
36. MligTC455_17197 170 3.54 Mlig455_053652

Neo: -

Age: -

1.814 - - - 0.976 0.838 - Mlig455_053652 {REF} {Length: 2429} {TRANSSPLICED} {RNA1509_44480} {RNA1310_34935, RNA1509_44480} {RNA1509_44480, RNA815_20343}
37. MligTC455_48785 525 10.94 Mlig455_045165

Neo: -

Age: -

DCAF7 1.813 0.827 - - 0.986 - - Mlig455_045165 {REF} {Length: 2087} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=26.2]} {Human: ENSG00000136485, DCAF7, DDB1 and CUL4 associated factor 7, [RH, Score=600, Expect=0.0]} {Mouse: ENSMUSG00000049354, Dcaf7, DDB1 and CUL4 associated factor 7, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0266848, wap, wings apart, [RH, Score=577, Expect=0.0]} {Celegans: WBGene00009976, swan-2, Seven WD repeats, AN11 family, [RH, Score=471, Expect=1e-165]} {Smed: dd_Smed_v6_3579_0_1, dd_Smed_v6_3579_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_38686} {RNA1310_14635, RNA1509_38686} {RNA1509_38686, RNA815_37344}
38. MligTC455_03382 210 4.37 Mlig455_057035

Neo: -

Age: -

Region-enriched R2: 3.628/0.00113

PDE1C 1.809 - - - 0.955 0.854 - Mlig455_057035 {REF} {Length: 2458} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=275.1]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=94.2]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Mouse: ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [RH, Score=538, Expect=0.0]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [RH, Score=482, Expect=2e-164]} {Smed: dd_Smed_v6_11039_0_2, dd_Smed_v6_11039_0_2, [RH, Score=613, Expect=0.0]} {RNA1509_46084} {RNA1310_8143.1} {RNA815_6002}
39. MligTC455_53249 690 14.38 Mlig455_027272, Mlig455_027319

Neo: -

Age: -

Region-enriched R5: 1.274/0.02479

WBP4 1.805 - - - 0.977 0.828 -

Mlig455_027272 {REF} {Length: 1151} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=42.3]; U1 zinc finger [PF06220.14, score=41.5]} {Human: ENSG00000120688, WBP4, WW domain binding protein 4, [Score=83.6, Expect=1e-17]} {Mouse: ENSMUSG00000022023, Wbp4, WW domain binding protein 4, [Score=88.6, Expect=1e-19]} {Dmel: FBgn0031287, CG4291, [RH, Score=91.3, Expect=5e-21]} {Smed: dd_Smed_v6_10030_0_6, dd_Smed_v6_10030_0_6, [RH, Score=87.4, Expect=1e-20]} {RNA1509_46002} {RNA1310_29789} {RNA815_12245}

Mlig455_027319 {REF} {Length: 1127} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=42.3]; U1 zinc finger [PF06220.14, score=41.5]} {Human: ENSG00000120688, WBP4, WW domain binding protein 4, [Score=81.6, Expect=5e-17]} {Mouse: ENSMUSG00000022023, Wbp4, WW domain binding protein 4, [Score=88.2, Expect=1e-19]} {Dmel: FBgn0031287, CG4291, [RH, Score=91.3, Expect=7e-21]} {Smed: dd_Smed_v6_10030_0_6, dd_Smed_v6_10030_0_6, [RH, Score=87.4, Expect=1e-20]} {RNA1509_46002} {RNA1310_29789} {RNA815_12245}
40. MligTC455_15942 908 18.92 Mlig455_035020, Mlig455_053446

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.273

NR1I2 1.802 0.967 - - - 0.835 -

Mlig455_035020 {REF} {Length: 4424} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.8]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.4, Expect=1e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.3, Expect=6e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=81.3, Expect=6e-16]} {Dmel: FBgn0003720, tll, tailless, [Score=82.0, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.4, Expect=2e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=3e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}

Mlig455_053446 {REF} {Length: 4372} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.7]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.0, Expect=2e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.0, Expect=9e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=80.9, Expect=8e-16]; ENSMUSG00000002393, Nr2f6, nuclear receptor subfamily 2, group F, member 6, [Score=80.1, Expect=1e-15]} {Dmel: FBgn0003720, tll, tailless, [Score=82.4, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.8, Expect=1e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=2e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}
41. MligTC455_52558 968 20.17 Mlig455_024460

Neo: -

Age: -

ANXA13 1.802 0.849 - - 0.953 - - Mlig455_024460 {REF} {Length: 1894} {Pfam: Annexin [PF00191.22, score=272.9]} {Human: ENSG00000104537, ANXA13, annexin A13, [Score=258, Expect=1e-84]; ENSG00000196975, ANXA4, annexin A4, [Score=251, Expect=2e-81]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [Score=244, Expect=4e-79]; ENSMUSG00000021866, Anxa11, annexin A11, [Score=239, Expect=5e-75]; ENSMUSG00000021950, Anxa8, annexin A8, [Score=234, Expect=2e-75]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [Score=244, Expect=3e-79]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=219, Expect=5e-68]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [Score=269, Expect=9e-85]} {RNA1509_21408, RNA1509_26616, RNA1509_29180} {RNA1310_4220.1, RNA1509_21408, RNA1509_26616, RNA1509_29180} {RNA1509_21408, RNA1509_26616, RNA1509_29180, RNA815_1223.1}
42. MligTC455_33552 905 18.86 Mlig455_014406, Mlig455_070160

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.705/0.03873

KCNH1 1.801 - - - 0.979 0.822 -

Mlig455_014406 {REF} {Length: 5774} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=54.1]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=269, Expect=1e-82]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=256, Expect=1e-74]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=267, Expect=4e-79]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=256, Expect=3e-75]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=283, Expect=5e-84]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=240, Expect=1e-69]} {Smed: dd_Smed_v6_23063_0_1, dd_Smed_v6_23063_0_1, [Score=283, Expect=7e-86]} {RNA1509_16580} {RNA1310_9615} {RNA815_20522}

Mlig455_070160 {REF} {Length: 3641} {Pfam: Ion transport protein [PF00520.33, score=111.5]; Cyclic nucleotide-binding domain [PF00027.31, score=53.3]; Ion channel [PF07885.18, score=40.6]} {Human: ENSG00000143473, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000283965, KCNH1, potassium voltage-gated channel subfamily H member 1, [Score=795, Expect=0.0]; ENSG00000140015, KCNH5, potassium voltage-gated channel subfamily H member 5, [Score=771, Expect=0.0]} {Mouse: ENSMUSG00000058248, Kcnh1, potassium voltage-gated channel, subfamily H (eag-related), member 1, [Score=794, Expect=0.0]; ENSMUSG00000034402, Kcnh5, potassium voltage-gated channel, subfamily H (eag-related), member 5, [Score=770, Expect=0.0]} {Dmel: FBgn0000535, eag, ether a go-go, [Score=838, Expect=0.0]} {Celegans: WBGene00001171, egl-2, EAG K+ channel EGL-2, [Score=688, Expect=0.0]} {Smed: dd_Smed_v6_18793_0_1, dd_Smed_v6_18793_0_1, [Score=895, Expect=0.0]} {RNA1509_16580} {RNA1310_6070} {RNA815_18231}
43. MligTC455_47803 609 12.69 Mlig455_042586

Neo: -

Age: -

Region-enriched R2: 2.248/0.00320

SMKR1 1.8 0.819 - - 0.981 - - Mlig455_042586 {REF} {Length: 1831} {TRANSSPLICED} {Human: ENSG00000240204, SMKR1, small lysine rich protein 1, [RH, Score=54.3, Expect=5e-11]} {Dmel: FBgn0266615, CG45122, [Score=41.6, Expect=5e-06]} {Smed: dd_Smed_v6_10158_0_1, dd_Smed_v6_10158_0_1, [RH, Score=44.3, Expect=3e-07]} {RNA1509_37781} {RNA1310_41265, RNA1509_37781} {RNA1509_37781, RNA815_11227.2}
44. MligTC455_17224 155 3.22 Mlig455_069916

Neo: -

Age: -

TBPL2 1.796 - - - 0.979 - 0.817 Mlig455_069916 {REF} {Length: 699} {Pfam: Transcription factor TFIID (or TATA-binding protein, TBP) [PF00352.23, score=46.0]} {Human: ENSG00000182521, TBPL2, TATA-box binding protein like 2, [Score=47.0, Expect=1e-06]; ENSG00000112592, TBP, TATA-box binding protein, [Score=45.1, Expect=5e-06]} {Mouse: ENSMUSG00000061809, Tbpl2, TATA box binding protein like 2, [Score=48.1, Expect=3e-07]} {Dmel: FBgn0003687, Tbp, TATA binding protein, [Score=48.1, Expect=2e-07]} {Celegans: WBGene00006577, tlf-1, TBP-Like Factor; TBP-like factor, [Score=45.8, Expect=1e-06]} {RNA1509_12203} {RNA1310_37970} {RNA815_7432}
45. MligTC455_44916 688 14.33 Mlig455_025259

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.436

GMPPA 1.796 0.844 - - 0.952 - - Mlig455_025259 {REF} {Length: 1859} {TRANSSPLICED} {Pfam: Nucleotidyl transferase [PF00483.25, score=97.0]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=29.6]; MobA-like NTP transferase domain [PF12804.9, score=21.3]} {Human: ENSG00000144591, GMPPA, GDP-mannose pyrophosphorylase A, [RH, Score=458, Expect=1e-159]} {Mouse: ENSMUSG00000033021, Gmppa, GDP-mannose pyrophosphorylase A, [RH, Score=461, Expect=4e-161]} {Dmel: FBgn0034035, CG8207, [RH, Score=450, Expect=1e-156]} {Celegans: WBGene00021628, Y47D9A.1, [RH, Score=398, Expect=9e-137]} {Smed: dd_Smed_v6_4150_0_1, dd_Smed_v6_4150_0_1, [RH, Score=496, Expect=6e-175]} {RNA1509_37379} {RNA1310_15544, RNA1509_37379} {RNA1509_37379, RNA815_10312.2}
46. MligTC455_47601 126 2.62 Mlig455_056477

Neo: -

Age: Up-Down-Up

NRXN1 1.796 - - - 0.958 0.838 - Mlig455_056477 {REF} {Length: 3481} {Pfam: Laminin G domain [PF02210.26, score=58.3]; Laminin G domain [PF00054.25, score=43.2]; Syndecan domain [PF01034.22, score=27.4]} {Human: ENSG00000179915, NRXN1, neurexin 1, [Score=142, Expect=4e-35]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=142, Expect=1e-35]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=102, Expect=2e-22]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [Score=142, Expect=8e-36]} {RNA1509_55888} {RNA1310_37025, RNA1509_55888} {RNA1509_55888, RNA815_22404}
47. MligTC455_50129 935 19.48 Mlig455_066199, Mlig455_068834

Neo: -

Age: -

BRAF 1.796 - - - 0.964 0.832 -

Mlig455_066199 {REF} {Length: 4134} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.8]; Protein kinase domain [PF00069.27, score=178.9]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=24.2]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=488, Expect=1e-159]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=486, Expect=3e-159]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=374, Expect=1e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=6e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=458, Expect=5e-149]} {RNA1509_5530} {RNA1310_8028.1, RNA1509_5530} {RNA1509_5530, RNA815_4195.1}

Mlig455_068834 {REF} {Length: 4180} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.0]; Protein kinase domain [PF00069.27, score=178.1]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=23.0]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=489, Expect=4e-160]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=488, Expect=7e-160]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=373, Expect=2e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=5e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=459, Expect=1e-149]} {RNA1509_5530} {RNA1310_9384} {RNA815_4195.1}
48. MligTC455_47441 543 11.32 Mlig455_045866

Neo: -

Age: -

1.793 0.969 - 0.824 - - - Mlig455_045866 {REF} {Length: 2993} {TRANSSPLICED} {Smed: dd_Smed_v6_11834_0_1, dd_Smed_v6_11834_0_1, [RH, Score=173, Expect=4e-47]} {RNA1509_34658, RNA1509_4754} {RNA1310_5693.1, RNA1509_34658, RNA1509_4754} {RNA1509_34658, RNA1509_4754, RNA815_2001}
49. MligTC455_22929 333 6.94 Mlig455_002604, Mlig455_050280

Neo: -

Age: -

AFTPH 1.79 - 0.827 - 0.963 - -

Mlig455_002604 {REF} {Length: 943} {RNA1509_3250} {RNA1310_7253.1} {RNA815_4748}

Mlig455_050280 {REF} {Length: 4398} {TRANSSPLICED} {Pfam: Clathrin-binding box of Aftiphilin, vesicle trafficking [PF15045.8, score=24.4]} {Human: ENSG00000119844, AFTPH, aftiphilin, [Score=69.7, Expect=1e-11]} {Mouse: ENSMUSG00000049659, Aftph, aftiphilin, [RH, Score=72.4, Expect=1e-12]} {RNA1509_3250, RNA1509_52946} {RNA1310_7253.1, RNA1509_52946} {RNA1509_52946, RNA815_5478}
50. MligTC455_40862 111 2.31 Mlig455_009631

Neo: -

Age: -

STOM 1.788 - - - 0.975 - 0.813 Mlig455_009631 {REF} {Length: 2320} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=127.1]; SPFH domain-Band 7 family [PF13421.8, score=19.4]} {Human: ENSG00000148175, STOM, stomatin, [Score=233, Expect=2e-73]; ENSG00000133115, STOML3, stomatin like 3, [Score=226, Expect=2e-70]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=233, Expect=2e-73]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=224, Expect=3e-70]} {Dmel: FBgn0260657, CG42540, [Score=248, Expect=4e-78]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=246, Expect=2e-78]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=280, Expect=4e-92]} {RNA1509_41852} {RNA1310_25287.1} {RNA815_18270.2}
51. MligTC455_51857 598 12.47 Mlig455_024455

Neo: -

Age: -

MDH1B 1.786 - - 0.829 0.957 - - Mlig455_024455 {REF} {Length: 1886} {Pfam: lactate/malate dehydrogenase, alpha/beta C-terminal domain [PF02866.20, score=38.0]} {Human: ENSG00000138400, MDH1B, malate dehydrogenase 1B, [RH, Score=258, Expect=2e-79]} {Mouse: ENSMUSG00000025963, Mdh1b, malate dehydrogenase 1B, NAD (soluble), [RH, Score=238, Expect=3e-72]} {Celegans: WBGene00018491, mdh-1, Malate DeHydrogenase, [Score=75.9, Expect=8e-15]} {Smed: dd_Smed_v6_10200_0_1, dd_Smed_v6_10200_0_1, [Score=279, Expect=6e-87]} {RNA1509_21048} {RNA1310_31155} {RNA815_18662}
52. MligTC455_35663 475 9.89 Mlig455_028426

Neo: -

Age: -

CLHC1 1.785 - - - 0.978 0.807 - Mlig455_028426 {REF} {Length: 1005} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.3]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [RH, Score=155, Expect=8e-40]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [RH, Score=160, Expect=8e-42]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=51.2, Expect=2e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [RH, Score=145, Expect=4e-37]} {RNA1509_25530} {RNA1310_5794.1} {RNA815_1706}
53. MligTC455_44925 2477 51.59 Mlig455_055034, Mlig455_055051

Neo: -

Age: Down-Up-Down

CNFN 1.776 - - - 0.957 - 0.819

Mlig455_055034 {REF} {Length: 1471} {Pfam: PLAC8 family [PF04749.19, score=76.7]} {Human: ENSG00000105427, CNFN, cornifelin, [Score=43.1, Expect=6e-06]} {Mouse: ENSMUSG00000063651, Cnfn, cornifelin, [Score=42.4, Expect=9e-06]} {Smed: dd_Smed_v6_743_0_1, dd_Smed_v6_743_0_1, [RH, Score=118, Expect=6e-36]} {RNA1509_20095} {RNA1310_43155} {RNA815_11481.1}

Mlig455_055051 {REF} {Length: 1454} {Pfam: PLAC8 family [PF04749.19, score=76.7]} {Human: ENSG00000105427, CNFN, cornifelin, [Score=43.1, Expect=6e-06]} {Mouse: ENSMUSG00000063651, Cnfn, cornifelin, [Score=42.4, Expect=9e-06]} {Smed: dd_Smed_v6_743_0_1, dd_Smed_v6_743_0_1, [RH, Score=118, Expect=6e-36]} {RNA1509_19118, RNA1509_20095} {RNA1310_43155, RNA1509_19118, RNA1509_20095} {RNA1509_19118, RNA1509_20095, RNA815_11481.1}
54. MligTC455_23809 119 2.47 Mlig455_065200

Neo: -

Age: -

1.774 - - - 0.981 0.793 - Mlig455_065200 {REF} {Length: 2060} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=33.7]} {RNA1509_46843} {RNA1310_11232} {RNA815_41042}
55. MligTC455_46575 1334 27.8 Mlig455_028040

Neo: -

Age: -

Region-enriched R6: 1.097/0.02048

ANGPT4 1.773 0.811 - - 0.962 - - Mlig455_028040 {REF} {Length: 4171} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=102.3]} {Human: ENSG00000101280, ANGPT4, angiopoietin 4, [Score=94.7, Expect=9e-20]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=90.9, Expect=2e-20]} {Mouse: ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=88.2, Expect=8e-18]; ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=84.7, Expect=1e-16]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=84.7, Expect=8e-17]; ENSMUSG00000027460, Angpt4, angiopoietin 4, [Score=84.0, Expect=2e-16]; ENSMUSG00000028001, Fga, fibrinogen alpha chain, [Score=84.0, Expect=4e-16]} {Dmel: FBgn0003326, sca, scabrous, [Score=92.8, Expect=3e-19]} {Celegans: WBGene00020516, T15B7.1, [RH, Score=70.9, Expect=7e-13]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=96.3, Expect=2e-20]} {RNA1509_37814} {RNA1310_10211.1} {RNA815_5198}
56. MligTC455_29377 169 3.51 Mlig455_032445

Neo: -

Age: logFC(26M/2M)=-0.946

1.771 - - - 0.975 0.796 - Mlig455_032445 {REF} {Length: 996} {NoTransDecoderORF} {RNA1509_42537} {RNA1310_16376} {RNA815_10254}
57. MligTC455_15569 487 10.15 Mlig455_067138, Mlig455_068636

Neo: -

Age: -

Region-enriched R2: 2.466/0.01939

1.77 - - - 0.961 - 0.809

Mlig455_067138 {REF} {Length: 332} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_27678} {RNA1310_35433} {RNA815_11024.1}

Mlig455_068636 {REF} {Length: 720} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_27678} {RNA1310_34530, RNA1509_27678} {RNA1509_27678, RNA815_11024.1}
58. MligTC455_48674 196 4.08 Mlig455_060643

Neo: -

Age: -

1.77 - 0.793 - 0.977 - - Mlig455_060643 {REF} {Length: 1133} {Pfam: WW domain-binding protein 1 [PF11669.10, score=22.7]} {RNA1310_20158.1} {RNA815_24401}
59. MligTC455_17539 396 8.24 Mlig455_020650

Neo: -

Age: logFC(26M/2M)=-0.311

RPGRIP1L 1.769 0.817 - - 0.952 - - Mlig455_020650 {REF} {Length: 4523} {TRANSSPLICED} {Pfam: First C2 domain of RPGR-interacting protein 1 [PF11618.10, score=156.0]; Retinitis pigmentosa G-protein regulator interacting C-terminal [PF18111.3, score=63.1]; C2 domain [PF00168.32, score=39.2]} {Human: ENSG00000103494, RPGRIP1L, RPGRIP1 like, [RH, Score=486, Expect=3e-150]} {Mouse: ENSMUSG00000033282, Rpgrip1l, Rpgrip1-like, [Score=448, Expect=3e-136]} {Smed: dd_Smed_v6_11425_0_1, dd_Smed_v6_11425_0_1, [RH, Score=489, Expect=2e-151]} {RNA1509_17201, RNA1509_3677, RNA1509_51934} {RNA1310_2541.1, RNA1509_17201, RNA1509_3677, RNA1509_51934} {RNA1509_17201, RNA1509_3677, RNA1509_51934, RNA815_452}
60. MligTC455_50128 1288 26.83 Mlig455_028373

Neo: -

Age: -

BRAF 1.767 - - - 0.974 0.793 - Mlig455_028373 {REF} {Length: 4173} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.0]; Protein kinase domain [PF00069.27, score=178.1]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=23.0]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=489, Expect=3e-160]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=488, Expect=7e-160]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=373, Expect=2e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=5e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=459, Expect=1e-149]} {RNA1509_5530} {RNA1310_8028.1} {RNA815_4195.1}
61. MligTC455_54194 156 3.25 Mlig455_066828

Neo: -

Age: logFC(26M/2M)=-0.485

1.765 0.951 0.814 - - - - Mlig455_066828 {REF} {Length: 1460} {RNA1509_54236} {RNA1310_18757.1, RNA1509_54236} {RNA1509_54236, RNA815_5768.1}
62. MligTC455_48044 893 18.59 Mlig455_035350, Mlig455_035391

Neo: -

Age: Down-Up-Down

1.764 - - - 0.964 - 0.800

Mlig455_035350 {REF} {Length: 672} {NoTransDecoderORF} {RNA1509_29779} {RNA1310_85066} {RNA815_47015}

Mlig455_035391 {REF} {Length: 576} {NoTransDecoderORF} {RNA1509_29779, RNA1509_45958} {RNA1310_85066, RNA1509_29779, RNA1509_45958} {RNA1509_29779, RNA1509_45958, RNA815_47015}
63. MligTC455_44975 612 12.76 Mlig455_029692, Mlig455_034837

Neo: -

Age: -

1.762 - - - 0.980 0.782 -

Mlig455_029692 {REF} {Length: 2167} {TRANSSPLICED} {RNA1509_49332} {RNA1310_7362.1, RNA1509_49332} {RNA1509_49332, RNA815_14078}

Mlig455_034837 {REF} {Length: 2191} {TRANSSPLICED} {RNA1509_49332} {RNA1310_7362.1} {RNA815_14078}
64. MligTC455_19595 465 9.68 Mlig455_043694, Mlig455_043763, Mlig455_047460

Neo: -

Age: -

TRPV5 1.761 - - - 0.963 0.798 -

Mlig455_043694 {REF} {Length: 3872} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=59.0]; Ankyrin repeat [PF00023.32, score=48.2]; Ankyrin repeats (many copies) [PF13857.8, score=46.8]; Ankyrin repeats (many copies) [PF13637.8, score=44.4]; Ankyrin repeat [PF13606.8, score=43.4]; Ion transport protein [PF00520.33, score=35.3]} {Human: ENSG00000127412, TRPV5, transient receptor potential cation channel subfamily V member 5, [RH, Score=213, Expect=4e-58]; ENSG00000274348, TRPV5, transient receptor potential cation channel subfamily V member 5, [RH, Score=213, Expect=4e-58]; ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=209, Expect=1e-56]; ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=208, Expect=1e-56]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [RH, Score=221, Expect=5e-61]} {Dmel: FBgn0036414, nan, nanchung, [RH, Score=623, Expect=0.0]} {Celegans: WBGene00003841, ocr-4, Osm-9 and Capsaicin receptor-Related, [RH, Score=496, Expect=1e-164]} {Smed: dd_Smed_v6_29474_0_1, dd_Smed_v6_29474_0_1, [RH, Score=407, Expect=1e-135]} {RNA1509_18898, RNA1509_5458} {RNA1310_14162.1, RNA1509_18898} {RNA1509_18898, RNA815_8880}

Mlig455_043763 {REF} {Length: 4095} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=62.4]; Ankyrin repeat [PF00023.32, score=54.6]; Ankyrin repeats (many copies) [PF13857.8, score=52.0]; Ankyrin repeats (many copies) [PF13637.8, score=51.7]; Ankyrin repeat [PF13606.8, score=48.1]} {Human: ENSG00000274348, TRPV5, transient receptor potential cation channel subfamily V member 5, [Score=193, Expect=2e-52]; ENSG00000127412, TRPV5, transient receptor potential cation channel subfamily V member 5, [Score=193, Expect=2e-52]; ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [Score=191, Expect=3e-51]; ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [Score=191, Expect=2e-51]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [Score=201, Expect=5e-55]} {Dmel: FBgn0036414, nan, nanchung, [Score=526, Expect=7e-178]} {Celegans: WBGene00003838, ocr-1, Osm-9 and Capsaicin receptor-Related, [Score=419, Expect=3e-136]} {Smed: dd_Smed_v6_29474_0_1, dd_Smed_v6_29474_0_1, [RH, Score=405, Expect=3e-137]} {RNA1509_5458} {RNA1310_14162.1} {RNA815_8880}

Mlig455_047460 {REF} {Length: 2006} {Dmel: FBgn0036414, nan, nanchung, [Score=45.8, Expect=2e-06]} {Smed: dd_Smed_v6_22272_0_2, dd_Smed_v6_22272_0_2, [Score=50.1, Expect=3e-08]} {RNA1509_5458} {RNA1310_27057.1} {RNA815_11034.1}
65. MligTC455_19996 1327 27.64 Mlig455_040679, Mlig455_064542

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.357

Region-enriched R4: 1.353/0.00087

1.76 0.960 - 0.800 - - -

Mlig455_040679 {REF} {Length: 1076} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=33.8]} {RNA1509_18707} {RNA1310_25620, RNA1509_18707} {RNA1509_18707, RNA815_17844}

Mlig455_064542 {REF} {Length: 1060} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=33.5]} {RNA1509_18707} {RNA1310_25620} {RNA815_17844}
66. MligTC455_42991 845 17.61 Mlig455_012402

Neo: -

Age: -

Region-enriched R2: 1.538/0.00957

TCTEX1D1 1.759 - 0.784 - 0.975 - - Mlig455_012402 {REF} {Length: 1295} {TRANSSPLICED} {Pfam: Tctex-1 family [PF03645.15, score=82.1]} {Human: ENSG00000152760, TCTEX1D1, Tctex1 domain containing 1, [RH, Score=144, Expect=2e-43]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [RH, Score=138, Expect=1e-41]} {Dmel: FBgn0037773, CG5359, [Score=70.5, Expect=2e-15]} {Smed: dd_Smed_v6_9321_0_2, dd_Smed_v6_9321_0_2, [RH, Score=172, Expect=1e-55]} {RNA1509_25208, RNA1509_50135} {RNA1310_1158.1, RNA1509_25208} {RNA1509_25208, RNA815_5483}
67. MligTC455_45304 418 8.71 Mlig455_056226

Neo: -

Age: -

ZDHHC9 1.757 - 0.788 - 0.969 - - Mlig455_056226 {REF} {Length: 2703} {TRANSSPLICED} {Pfam: DHHC palmitoyltransferase [PF01529.22, score=139.7]} {Human: ENSG00000188706, ZDHHC9, zinc finger DHHC-type containing 9, [Score=308, Expect=7e-102]; ENSG00000175048, ZDHHC14, zinc finger DHHC-type containing 14, [Score=307, Expect=3e-100]} {Mouse: ENSMUSG00000036985, Zdhhc9, zinc finger, DHHC domain containing 9, [Score=309, Expect=1e-102]; ENSMUSG00000034265, Zdhhc14, zinc finger, DHHC domain containing 14, [Score=302, Expect=3e-98]} {Dmel: FBgn0260941, app, approximated, [Score=289, Expect=3e-94]} {Celegans: WBGene00012948, dhhc-2, Palmitoyltransferase, [RH, Score=221, Expect=6e-68]} {Smed: dd_Smed_v6_9975_0_1, dd_Smed_v6_9975_0_1, [RH, Score=295, Expect=6e-97]} {RNA1509_35241} {RNA1310_8511.2} {RNA815_8570}
68. MligTC455_32649 635 13.24 Mlig455_012540

Neo: -

Age: -

VPS18 1.75 0.784 - - 0.966 - - Mlig455_012540 {REF} {Length: 3701} {TRANSSPLICED} {Pfam: Pep3/Vps18/deep orange family [PF05131.16, score=72.8]} {Human: ENSG00000104142, VPS18, VPS18, CORVET/HOPS core subunit, [RH, Score=401, Expect=4e-124]} {Mouse: ENSMUSG00000034216, Vps18, VPS18 CORVET/HOPS core subunit, [RH, Score=399, Expect=4e-123]} {Dmel: FBgn0000482, dor, Diabetes and obesity regulated, [RH, Score=311, Expect=7e-91]} {Celegans: WBGene00021058, vps-18, Related to yeast Vacuolar Protein Sorting factor, [RH, Score=213, Expect=4e-57]} {Smed: dd_Smed_v6_4550_0_1, dd_Smed_v6_4550_0_1, [RH, Score=300, Expect=2e-87]} {RNA1509_37938, RNA1509_53896} {RNA1310_4955, RNA1509_53896} {RNA1509_53896, RNA815_2230.1}
69. MligTC455_20664 130 2.7 Mlig455_031330

Neo: Neoblast, stringent

Age: Up-Down-Up, logFC(26M/2M)=0.449

HELLS 1.748 - - - 0.972 0.776 - Mlig455_031330 {REF} {Length: 4396} {TRANSSPLICED} {Pfam: SNF2-related domain [PF00176.25, score=210.0]; Helicase conserved C-terminal domain [PF00271.33, score=64.4]; Type III restriction enzyme, res subunit [PF04851.17, score=24.2]; Class II histone deacetylase complex subunits 2 and 3 [PF11496.10, score=21.7]} {Human: ENSG00000119969, HELLS, helicase, lymphoid specific, [RH, Score=601, Expect=0.0]} {Mouse: ENSMUSG00000025001, Hells, helicase, lymphoid specific, [Score=600, Expect=0.0]} {Dmel: FBgn0000212, brm, brahma, [Score=245, Expect=6e-67]} {Celegans: WBGene00004204, swsn-4, SWI/SNF nucleosome remodeling complex component; SWI2/SNF2-like protein, [Score=240, Expect=2e-65]} {Smed: dd_Smed_v6_7560_0_1, dd_Smed_v6_7560_0_1, [Score=300, Expect=1e-89]} {RNA1509_22520} {RNA1310_5705} {RNA815_1136}
70. MligTC455_22792 813 16.94 Mlig455_006911

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.573

PPP1R10 1.746 0.762 - - 0.984 - - Mlig455_006911 {REF} {Length: 4431} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=34.5} {Pfam: TFIIS helical bundle-like domain [PF08711.13, score=20.9]; Negative regulator of genetic competence (MecA) [PF05389.14, score=18.7]} {Human: ENSG00000204569, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000230995, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000238104, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000235291, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000206489, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000227804, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000231737, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]} {Mouse: ENSMUSG00000039220, Ppp1r10, protein phosphatase 1, regulatory subunit 10, [RH, Score=95.1, Expect=2e-19]} {Dmel: FBgn0053526, PNUTS, [RH, Score=87.4, Expect=4e-17]} {Smed: dd_Smed_v6_3726_0_1, dd_Smed_v6_3726_0_1, [Score=93.2, Expect=2e-19]} {RNA1509_35861, RNA1509_3759, RNA1509_41300} {RNA1310_6625, RNA1509_35861, RNA1509_41300} {RNA1509_35861, RNA1509_41300, RNA815_5489}
71. MligTC455_31980 220 4.59 Mlig455_007685, Mlig455_020875

Neo: -

Age: Up-Down-Up

DIS3L2 1.745 - - - 0.977 0.768 -

Mlig455_007685 {REF} {Length: 2832} {TRANSSPLICED} {Pfam: RNB domain [PF00773.21, score=281.5]; DIS3-like exonuclease 2 C terminal [PF17877.3, score=37.2]; Dis3-like cold-shock domain 2 (CSD2) [PF17849.3, score=37.1]; Rrp44-like cold shock domain [PF17216.5, score=27.4]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=375, Expect=3e-116]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=380, Expect=1e-118]} {Dmel: FBgn0035111, Dis3l2, Dis3 like 3'-5' exoribonuclease 2, [Score=264, Expect=9e-75]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=335, Expect=3e-102]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=349, Expect=2e-107]} {RNA1509_57497} {RNA1310_4374.2} {RNA815_1234.1}

Mlig455_020875 {REF} {Length: 1339} {Pfam: DIS3-like exonuclease 2 C terminal [PF17877.3, score=38.1]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=53.9, Expect=7e-08]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=53.1, Expect=9e-08]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=49.7, Expect=6e-07]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=69.3, Expect=1e-13]} {RNA1509_57497} {RNA1310_47825} {RNA815_1234.1}
72. MligTC455_39222 213 4.44 Mlig455_064653, Mlig455_064686

Neo: -

Age: -

Region-enriched R2: 4.317/0.00597

1.745 - - - 0.968 0.777 -

Mlig455_064653 {REF} {Length: 2836} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.9, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=7e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_56255} {RNA1310_13407} {RNA815_38407}

Mlig455_064686 {REF} {Length: 3820} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.5, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=8e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_50956} {RNA1310_13407} {RNA815_38407}
73. MligTC455_17506 450 9.38 Mlig455_015262

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.648

Region-enriched R4: 1.874/0.03652

1.743 - - - 0.960 0.783 - Mlig455_015262 {REF} {Length: 2975} {TRANSSPLICED} {RNA1509_4515} {RNA1310_5427} {RNA815_2140.1}
74. MligTC455_34982 318 6.62 Mlig455_069058

Neo: -

Age: -

1.74 - - - 0.972 0.768 - Mlig455_069058 {REF} {Length: 1143} {RNA1509_46243} {RNA1310_16643} {RNA815_21897}
75. MligTC455_10918 422 8.79 Mlig455_047587, Mlig455_047602

Neo: -

Age: -

ASIC2 1.739 - - - 0.968 - 0.771

Mlig455_047587 {REF} {Length: 2857} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=295.2]} {Human: ENSG00000108684, ASIC2, acid sensing ion channel subunit 2, [RH, Score=139, Expect=2e-34]; ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [RH, Score=133, Expect=9e-33]} {Mouse: ENSMUSG00000020704, Asic2, acid-sensing (proton-gated) ion channel 2, [RH, Score=137, Expect=3e-34]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [RH, Score=137, Expect=4e-34]} {Dmel: FBgn0052792, ppk8, pickpocket 8, [RH, Score=65.9, Expect=5e-11]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [RH, Score=162, Expect=2e-43]} {Smed: dd_Smed_v6_11787_0_1, dd_Smed_v6_11787_0_1, [Score=387, Expect=3e-129]} {RNA1509_23163} {RNA1310_6510} {RNA815_3823}

Mlig455_047602 {REF} {Length: 2812} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=295.2]} {Human: ENSG00000108684, ASIC2, acid sensing ion channel subunit 2, [RH, Score=139, Expect=2e-34]; ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [RH, Score=133, Expect=9e-33]} {Mouse: ENSMUSG00000020704, Asic2, acid-sensing (proton-gated) ion channel 2, [RH, Score=137, Expect=3e-34]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [RH, Score=137, Expect=4e-34]} {Dmel: FBgn0052792, ppk8, pickpocket 8, [RH, Score=65.9, Expect=5e-11]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [RH, Score=162, Expect=2e-43]} {Smed: dd_Smed_v6_11787_0_1, dd_Smed_v6_11787_0_1, [Score=387, Expect=3e-129]} {RNA1509_23163} {RNA1310_6510, RNA1509_23163} {RNA1509_23163, RNA815_3823}
76. MligTC455_44091 715 14.9 Mlig455_062506

Neo: -

Age: -

1.739 - - - 0.950 0.789 - Mlig455_062506 {REF} {Length: 3043} {TRANSSPLICED} {RNA1509_6174} {RNA1310_5481} {RNA815_11204}
77. MligTC455_36310 356 7.42 Mlig455_035589, Mlig455_051880

Neo: -

Age: -

1.738 - - - 0.968 - 0.770

Mlig455_035589 {REF} {Length: 2100} {Pfam: PH domain [PF00169.31, score=29.6]} {RNA1509_47709} {RNA1310_34455} {RNA815_4675.1}

Mlig455_051880 {REF} {Length: 2495} {Pfam: PH domain [PF00169.31, score=28.5]} {RNA1509_47709} {RNA1310_30265.1} {RNA815_4675.1}
78. MligTC455_41326 407 8.48 Mlig455_011060

Neo: -

Age: -

KCNA2 1.737 - - - 0.981 0.756 - Mlig455_011060 {REF} {Length: 6096} {Pfam: Ion transport protein [PF00520.33, score=161.6]; BTB/POZ domain [PF02214.24, score=99.2]; Ion channel [PF07885.18, score=50.3]} {Human: ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=620, Expect=0.0]; ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=617, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=611, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=619, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=617, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=643, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=383, Expect=6e-127]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=715, Expect=0.0]} {RNA1509_19798} {RNA1310_8877, RNA1509_19798} {RNA1509_19798, RNA815_8082.1}
79. MligTC455_42992 850 17.72 Mlig455_012830

Neo: -

Age: -

Region-enriched R2: 1.532/0.00966

TCTEX1D1 1.736 - 0.770 - 0.966 - - Mlig455_012830 {REF} {Length: 1216} {TRANSSPLICED} {Pfam: Tctex-1 family [PF03645.15, score=81.4]} {Human: ENSG00000152760, TCTEX1D1, Tctex1 domain containing 1, [RH, Score=143, Expect=2e-43]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [RH, Score=138, Expect=2e-41]} {Dmel: FBgn0037773, CG5359, [Score=70.1, Expect=2e-15]} {Celegans: WBGene00008764, dylt-1, DYnein Light chain (Tctex type), [Score=50.8, Expect=8e-09]} {Smed: dd_Smed_v6_9321_0_2, dd_Smed_v6_9321_0_2, [RH, Score=172, Expect=3e-55]} {RNA1509_33819, RNA1509_50135} {RNA1310_32303, RNA1509_33819, RNA1509_50135} {RNA1509_33819, RNA1509_50135, RNA815_5483}
80. MligTC455_00831 642 13.37 Mlig455_016457, Mlig455_016523

Neo: -

Age: logFC(26M/2M)=0.506

LGR5 1.735 0.771 - - 0.964 - -

Mlig455_016457 {REF} {Length: 4347} {Pfam: Leucine rich repeat [PF13855.8, score=86.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=45.8]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=40.5]} {Human: ENSG00000139292, LGR5, leucine rich repeat containing G protein-coupled receptor 5, [Score=58.5, Expect=7e-08]; ENSG00000145147, SLIT2, slit guidance ligand 2, [Score=57.0, Expect=2e-07]} {Mouse: ENSMUSG00000020140, Lgr5, leucine rich repeat containing G protein coupled receptor 5, [Score=59.7, Expect=2e-08]} {Dmel: FBgn0267435, chp, chaoptin, [Score=67.0, Expect=8e-11]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=55.8, Expect=2e-07]} {RNA1509_8817} {RNA1310_2409} {RNA815_590.1}

Mlig455_016523 {REF} {Length: 3360} {Pfam: Leucine rich repeat [PF13855.8, score=41.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.1]} {RNA1509_8817} {RNA1310_22547} {RNA815_590.1}
81. MligTC455_36484 730 15.2 Mlig455_008622

Neo: -

Age: -

TAF5 1.735 0.757 - - 0.978 - - Mlig455_008622 {REF} {Length: 5592} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; WD40 associated region in TFIID subunit, NTD2 domain [PF04494.17, score=90.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.2]; WD40 region of Ge1, enhancer of mRNA-decapping protein [PF16529.7, score=17.8]} {Human: ENSG00000148835, TAF5, TATA-box binding protein associated factor 5, [RH, Score=426, Expect=2e-138]} {Mouse: ENSMUSG00000025049, Taf5, TATA-box binding protein associated factor 5, [RH, Score=426, Expect=9e-139]} {Dmel: FBgn0010356, Taf5, TBP-associated factor 5, [RH, Score=380, Expect=2e-122]} {Celegans: WBGene00006386, taf-5, TAF (TBP-associated transcription factor) family, [RH, Score=254, Expect=3e-75]} {Smed: dd_Smed_v6_7319_0_1, dd_Smed_v6_7319_0_1, [RH, Score=311, Expect=2e-96]} {RNA1509_15120} {RNA1310_12001, RNA1509_15120} {RNA1509_15120, RNA815_9687}
82. MligTC455_29018 1803 37.56 Mlig455_033521

Neo: -

Age: -

1.73 0.769 - - 0.961 - - Mlig455_033521 {REF} {Length: 44} {NoTransDecoderORF}
83. MligTC455_28937 716 14.92 Mlig455_058348

Neo: -

Age: logFC(26M/2M)=-0.290

1.728 0.765 - - 0.963 - - Mlig455_058348 {REF} {Length: 8368} {Celegans: WBGene00015646, mlt-10, [Score=164, Expect=2e-43]} {RNA1509_21262, RNA1509_24069} {RNA1310_22909, RNA1509_21262} {RNA1509_21262, RNA815_15064}
84. MligTC455_20434 128 2.66 Mlig455_033593

Neo: -

Age: Up-Down-Up

URGCP 1.726 - - - 0.959 0.767 - Mlig455_033593 {REF} {Length: 3399} {Pfam: Root hair defective 3 GTP-binding protein (RHD3) [PF05879.14, score=31.0]; Dynamin family [PF00350.25, score=25.2]; 50S ribosome-binding GTPase [PF01926.25, score=19.0]} {Human: ENSG00000106608, URGCP, upregulator of cell proliferation, [Score=131, Expect=2e-30]} {Mouse: ENSMUSG00000078606, Gm4070, predicted gene 4070, [Score=389, Expect=2e-114]; ENSMUSG00000045868, Gvin1, GTPase, very large interferon inducible 1, [Score=389, Expect=4e-114]} {RNA1509_1613} {RNA1310_753} {RNA815_297.1}
85. MligTC455_42465 378 7.88 Mlig455_050238

Neo: -

Age: -

CCDC74B 1.726 0.958 0.768 - - - - Mlig455_050238 {REF} {Length: 2734} {TRANSSPLICED} {Pfam: Coiled-coil domain of unknown function [PF14916.8, score=52.5]; Coiled coil protein 74, C terminal [PF14917.8, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.9]} {Human: ENSG00000152076, CCDC74B, coiled-coil domain containing 74B, [RH, Score=57.4, Expect=1e-08]; ENSG00000163040, CCDC74A, coiled-coil domain containing 74A, [RH, Score=57.0, Expect=1e-08]} {Mouse: ENSMUSG00000041617, Ccdc74a, coiled-coil domain containing 74A, [RH, Score=54.3, Expect=5e-09]} {RNA1509_28309} {RNA1310_23099.2, RNA1509_28309} {RNA1509_28309, RNA815_11185}
86. MligTC455_16899 789 16.45 Mlig455_054163, Mlig455_060701

Neo: -

Age: -

1.724 0.767 - - 0.957 - -

Mlig455_054163 {REF} {Length: 1573} {RNA1509_32433} {RNA1310_22335} {RNA815_10376}

Mlig455_060701 {REF} {Length: 1510} {RNA1509_32433} {RNA1310_22335} {RNA815_10376}
87. MligTC455_28022 319 6.65 Mlig455_042317

Neo: -

Age: -

1.724 - 0.755 - 0.969 - - Mlig455_042317 {REF} {Length: 246} {NoTransDecoderORF} {RNA1509_117} {RNA1310_851.1} {RNA815_6853}
88. MligTC455_18369 234 4.87 Mlig455_015695

Neo: -

Age: -

1.723 - - - 0.960 - 0.763 Mlig455_015695 {REF} {Length: 1855} {TRANSSPLICED} {RNA1509_58191} {RNA1310_66702.1} {RNA815_46154}
89. MligTC455_41177 2418 50.38 Mlig455_049465

Neo: -

Age: logFC(26M/2M)=0.246

SNAP29 1.717 0.750 - - 0.967 - - Mlig455_049465 {REF} {Length: 1315} {TRANSSPLICED} {Human: ENSG00000099940, SNAP29, synaptosome associated protein 29, [RH, Score=99.0, Expect=5e-24]} {Mouse: ENSMUSG00000022765, Snap29, synaptosomal-associated protein 29, [RH, Score=89.4, Expect=1e-20]} {Celegans: WBGene00019305, snap-29, Soluble NSF attachment protein 29, [RH, Score=85.9, Expect=2e-19]} {Smed: dd_Smed_v6_1819_0_1, dd_Smed_v6_1819_0_1, [Score=125, Expect=6e-35]} {RNA1509_28228} {RNA1310_25746, RNA1509_28228} {RNA1509_28228, RNA815_5.1}
90. MligTC455_52703 503 10.48 Mlig455_067967

Neo: -

Age: Up-Down-Up

DSCAM 1.715 0.742 - - 0.973 - - Mlig455_067967 {REF} {Length: 7940} {Pfam: Fibronectin type III domain [PF00041.23, score=181.2]; Immunoglobulin domain [PF13927.8, score=132.1]; Immunoglobulin I-set domain [PF07679.18, score=91.0]; Immunoglobulin domain [PF13895.8, score=77.5]; Immunoglobulin domain [PF00047.27, score=62.1]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=49.3]; Immunoglobulin V-set domain [PF07686.19, score=46.5]} {Human: ENSG00000171587, DSCAM, DS cell adhesion molecule, [RH, Score=242, Expect=2e-63]; ENSG00000177103, DSCAML1, DS cell adhesion molecule like 1, [RH, Score=239, Expect=3e-62]} {Mouse: ENSMUSG00000050272, Dscam, DS cell adhesion molecule, [RH, Score=238, Expect=3e-62]; ENSMUSG00000032087, Dscaml1, DS cell adhesion molecule like 1, [RH, Score=238, Expect=2e-62]} {Dmel: FBgn0263219, Dscam4, Down syndrome cell adhesion molecule 4, [Score=221, Expect=4e-57]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=79.7, Expect=2e-14]} {Smed: dd_Smed_v6_3024_0_1, dd_Smed_v6_3024_0_1, [RH, Score=330, Expect=1e-90]} {RNA1509_2497} {RNA1310_1699.1} {RNA815_16029}
91. MligTC455_32752 991 20.65 Mlig455_048936, Mlig455_048957

Neo: -

Age: -

AGAP3 1.711 - - 0.752 0.959 - -

Mlig455_048936 {REF} {Length: 2649} {Pfam: Putative GTPase activating protein for Arf [PF01412.20, score=114.5]; PH domain [PF00169.31, score=21.9]} {Human: ENSG00000133612, AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=250, Expect=3e-73]} {Mouse: ENSMUSG00000023353, Agap3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=242, Expect=3e-72]} {Dmel: FBgn0028509, CenG1A, Centaurin gamma 1A, [Score=181, Expect=7e-48]} {Celegans: WBGene00000566, cnt-2, Arf-GAP with ANK repeat and PH domain-containing protein cnt-2, [Score=146, Expect=3e-36]} {Smed: dd_Smed_v6_4301_0_2, dd_Smed_v6_4301_0_2, [Score=248, Expect=4e-70]} {RNA1509_54301} {RNA1310_18299} {RNA815_29402}

Mlig455_048957 {REF} {Length: 11921} {Pfam: Putative GTPase activating protein for Arf [PF01412.20, score=114.5]; PH domain [PF00169.31, score=21.9]} {Human: ENSG00000133612, AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=249, Expect=3e-73]} {Mouse: ENSMUSG00000023353, Agap3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=243, Expect=3e-72]} {Dmel: FBgn0028509, CenG1A, Centaurin gamma 1A, [Score=181, Expect=8e-48]} {Celegans: WBGene00000566, cnt-2, Arf-GAP with ANK repeat and PH domain-containing protein cnt-2, [Score=145, Expect=2e-36]} {Smed: dd_Smed_v6_4301_0_2, dd_Smed_v6_4301_0_2, [Score=248, Expect=3e-70]} {RNA1509_54301} {RNA1310_18299} {RNA815_29402}
92. MligTC455_46959 842 17.54 Mlig455_003589

Neo: -

Age: -

Region-enriched R3: 1.028/0.03879

WBP2NL 1.709 - - - 0.973 - 0.736 Mlig455_003589 {REF} {Length: 2059} {Human: ENSG00000183066, WBP2NL, WBP2 N-terminal like, [Score=55.1, Expect=1e-08]} {Mouse: ENSMUSG00000022455, Wbp2nl, WBP2 N-terminal like, [Score=53.5, Expect=5e-08]} {Dmel: FBgn0038642, Muc91C, Mucin 91C, [Score=56.6, Expect=4e-09]} {RNA1509_43757} {RNA1310_14041, RNA1509_43757} {RNA1509_43757, RNA815_5513.1}
93. MligTC455_50724 402 8.37 Mlig455_007823

Neo: -

Age: -

Region-enriched R5: 1.057/0.03844

NRBP1 1.706 - - - 0.980 0.726 - Mlig455_007823 {REF} {Length: 5624} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=66.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=37.5]} {Human: ENSG00000115216, NRBP1, nuclear receptor binding protein 1, [RH, Score=188, Expect=4e-50]} {Mouse: ENSMUSG00000029148, Nrbp1, nuclear receptor binding protein 1, [RH, Score=184, Expect=6e-49]} {Dmel: FBgn0027497, Madm, MLF1-adaptor molecule, [RH, Score=153, Expect=4e-38]} {Celegans: WBGene00010427, hpo-11, [RH, Score=169, Expect=1e-43]} {Smed: dd_Smed_v6_5859_0_1, dd_Smed_v6_5859_0_1, [RH, Score=199, Expect=3e-52]} {RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1310_6856, RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1509_18578, RNA1509_19619, RNA1509_33489, RNA815_11040}
94. MligTC455_50228 1128 23.5 Mlig455_016788, Mlig455_016809

Neo: -

Age: -

RAB5B 1.704 0.734 - - 0.970 - -

Mlig455_016788 {REF} {Length: 1792} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296, RNA1509_42263} {RNA1310_25305, RNA1509_42263} {RNA1509_42263, RNA815_10567}

Mlig455_016809 {REF} {Length: 1784} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296} {RNA1310_25305, RNA1509_2296} {RNA1509_2296, RNA815_10567}
95. MligTC455_43590 1860 38.74 Mlig455_035222

Neo: -

Age: -

1.703 - 0.729 - 0.974 - - Mlig455_035222 {REF} {Length: 1270} {TRANSSPLICED} {Pfam: Rhodanese-like domain [PF00581.22, score=45.9]} {Dmel: FBgn0039145, CG6000, [RH, Score=73.6, Expect=2e-17]} {Smed: dd_Smed_v6_530_0_1, dd_Smed_v6_530_0_1, [RH, Score=50.4, Expect=1e-08]} {RNA1509_13777, RNA1509_33223, RNA1509_50550, RNA1509_7047, RNA1509_8867} {RNA1310_22990.1, RNA1509_13777, RNA1509_33223, RNA1509_50550, RNA1509_7047, RNA1509_8867} {RNA1509_13777, RNA1509_33223, RNA1509_50550, RNA1509_7047, RNA1509_8867, RNA815_11557}
96. MligTC455_47236 631 13.14 Mlig455_011561

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.763

UBASH3B 1.702 - - - 0.974 0.728 - Mlig455_011561 {REF} {Length: 5217} {Pfam: Histidine phosphatase superfamily (branch 1) [PF00300.24, score=51.3]} {Human: ENSG00000154127, UBASH3B, ubiquitin associated and SH3 domain containing B, [RH, Score=153, Expect=2e-38]} {Mouse: ENSMUSG00000032020, Ubash3b, ubiquitin associated and SH3 domain containing, B, [RH, Score=154, Expect=2e-39]} {Dmel: FBgn0039137, CG13604, [RH, Score=120, Expect=5e-28]} {Celegans: WBGene00020321, T07F12.1, [RH, Score=116, Expect=8e-29]} {Smed: dd_Smed_v6_12024_0_1, dd_Smed_v6_12024_0_1, [RH, Score=162, Expect=5e-42]} {RNA1509_10245, RNA1509_27327} {RNA1310_4087.1, RNA1509_27327} {RNA1509_27327, RNA815_2334.1}
97. MligTC455_37577 942 19.63 Mlig455_032156, Mlig455_032162, Mlig455_067630

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.122/0.04027

1.696 - - - 0.963 - 0.733

Mlig455_032156 {REF} {Length: 1459} {RNA1310_42557} {RNA815_22443}

Mlig455_032162 {REF} {Length: 1492} {RNA1310_8269} {RNA815_22443}

Mlig455_067630 {REF} {Length: 960} {RNA1310_42557} {RNA815_22443}
98. MligTC455_15829 660 13.76 Mlig455_002880

Neo: -

Age: -

KY 1.695 0.735 - - 0.960 - - Mlig455_002880 {REF} {Length: 6997} {TRANSSPLICED} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=105, Expect=4e-22]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=106, Expect=1e-22]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=209, Expect=3e-55]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=173, Expect=1e-45]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [RH, Score=561, Expect=3e-170]} {RNA1509_40353, RNA1509_43981, RNA1509_6471} {RNA1310_662.1, RNA1509_40353, RNA1509_43981} {RNA1509_40353, RNA1509_43981, RNA815_228}
99. MligTC455_22620 636 13.24 Mlig455_068319

Neo: -

Age: logFC(26M/2M)=-0.236

SUCLA2 1.692 - - - 0.977 0.715 - Mlig455_068319 {REF} {Length: 3077} {Pfam: ATP-grasp domain [PF08442.12, score=221.5]; CoA-ligase [PF00549.21, score=96.1]; ATP-grasp domain [PF13549.8, score=22.1]} {Human: ENSG00000136143, SUCLA2, succinate-CoA ligase ADP-forming beta subunit, [RH, Score=582, Expect=0.0]} {Mouse: ENSMUSG00000022110, Sucla2, succinate-Coenzyme A ligase, ADP-forming, beta subunit, [RH, Score=580, Expect=0.0]} {Dmel: FBgn0037643, skap, skpA associated protein, [RH, Score=491, Expect=2e-171]} {Celegans: WBGene00009812, suca-1, Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, [RH, Score=519, Expect=0.0]} {Smed: dd_Smed_v6_2298_0_1, dd_Smed_v6_2298_0_1, [RH, Score=610, Expect=0.0]} {RNA1509_25238, RNA1509_2992} {RNA1310_11624.1, RNA1509_25238} {RNA1509_25238, RNA815_4199.1}
100. MligTC455_40052 513 10.68 Mlig455_035856

Neo: -

Age: -

1.69 0.964 - - - 0.726 - Mlig455_035856 {REF} {Length: 3180} {TRANSSPLICED} {Smed: dd_Smed_v6_14291_0_1, dd_Smed_v6_14291_0_1, [RH, Score=221, Expect=3e-61]} {RNA1509_6964} {RNA1310_5805} {RNA815_1720}

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