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Results for MligTC455_41078

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_41078 2582 53.80 Mlig455_031144, Mlig455_031152

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.405

Region-enriched R5: 1.731/0.00002

Regeneration-upregulated BL: 2.286

Regeneration-enriched BL: 2.286

CDC20, SLC8A3

Mlig455_031144 {REF} {Length: 2272} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=48.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=46.2]} {Human: ENSG00000117399, CDC20, cell division cycle 20, [RH, Score=353, Expect=2e-115]} {Mouse: ENSMUSG00000006398, Cdc20, cell division cycle 20, [RH, Score=363, Expect=3e-119]} {Dmel: FBgn0001086, fzy, fizzy, [RH, Score=324, Expect=5e-104]} {Celegans: WBGene00001510, fzr-1, FiZzy Related family, [Score=261, Expect=2e-78]} {Smed: dd_Smed_v6_4796_0_1, dd_Smed_v6_4796_0_1, [Score=249, Expect=8e-76]} {RNA1509_30656, RNA1509_3584, RNA1509_38107} {RNA1310_10696, RNA1509_30656, RNA1509_3584, RNA1509_38107} {RNA1509_30656, RNA1509_3584, RNA1509_38107, RNA815_5941}

Mlig455_031152 {REF} {Length: 3629} {Pfam: Calx-beta domain [PF03160.16, score=119.6]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=92.2]; Sodium/calcium exchanger protein [PF01699.26, score=67.9]; WD domain, G-beta repeat [PF00400.34, score=48.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=40.8]} {Human: ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [Score=469, Expect=3e-150]; ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [Score=446, Expect=2e-140]} {Mouse: ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [Score=466, Expect=9e-149]; ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [Score=450, Expect=1e-142]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [Score=444, Expect=6e-144]} {Celegans: WBGene00003567, ncx-2, Na/Ca eXchangers, [Score=444, Expect=7e-141]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [Score=491, Expect=5e-159]} {RNA1509_30656} {RNA1310_10696} {RNA815_5941}

Cumulative graph for MligTC455_41078

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.147 5.905 0.85541 1.00000
RegionR2 -0.281 5.905 0.58960 0.94344
RegionR3 -0.913 5.905 0.04260 0.36019
RegionR4 0.33 5.905 0.47164 0.79962
RegionR5 1.731 5.905 0.00000 0.00002
RegionR6 0.833 5.905 0.02989 0.31882
RegionR7 0.489 5.905 0.27639 0.90715
RegionR8 -2.336 5.905 0.00243 0.08439

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.204 5.905 0.85433 1.00000
RegenerationR2 0.962 5.905 0.04664 0.35639
RegenerationR3 1.87 5.905 0.00037 0.02706
RegenerationR4 0.746 5.905 0.14705 0.57354
RegenerationR5 0.777 5.905 0.08883 0.45891
RegenerationR6 1.328 5.905 0.00623 0.09604
RegenerationBL 2.286 5.905 0.00000 0.00016 Specific for BL: 2.286
RegenerationTP 1.338 5.905 0.02664 0.27498


Genes with expression patterns similar to MligTC455_41078

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_41078 2582 53.8 Mlig455_031144, Mlig455_031152

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.405

Region-enriched R5: 1.731/0.00002

Regeneration-upregulated BL: 2.286

Regeneration-enriched BL: 2.286

CDC20, SLC8A3 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_031144 {REF} {Length: 2272} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=48.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=46.2]} {Human: ENSG00000117399, CDC20, cell division cycle 20, [RH, Score=353, Expect=2e-115]} {Mouse: ENSMUSG00000006398, Cdc20, cell division cycle 20, [RH, Score=363, Expect=3e-119]} {Dmel: FBgn0001086, fzy, fizzy, [RH, Score=324, Expect=5e-104]} {Celegans: WBGene00001510, fzr-1, FiZzy Related family, [Score=261, Expect=2e-78]} {Smed: dd_Smed_v6_4796_0_1, dd_Smed_v6_4796_0_1, [Score=249, Expect=8e-76]} {RNA1509_30656, RNA1509_3584, RNA1509_38107} {RNA1310_10696, RNA1509_30656, RNA1509_3584, RNA1509_38107} {RNA1509_30656, RNA1509_3584, RNA1509_38107, RNA815_5941}

Mlig455_031152 {REF} {Length: 3629} {Pfam: Calx-beta domain [PF03160.16, score=119.6]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=92.2]; Sodium/calcium exchanger protein [PF01699.26, score=67.9]; WD domain, G-beta repeat [PF00400.34, score=48.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=40.8]} {Human: ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [Score=469, Expect=3e-150]; ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [Score=446, Expect=2e-140]} {Mouse: ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [Score=466, Expect=9e-149]; ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [Score=450, Expect=1e-142]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [Score=444, Expect=6e-144]} {Celegans: WBGene00003567, ncx-2, Na/Ca eXchangers, [Score=444, Expect=7e-141]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [Score=491, Expect=5e-159]} {RNA1509_30656} {RNA1310_10696} {RNA815_5941}
2. MligTC455_47726 1983 41.3 Mlig455_021500, Mlig455_063198

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.718/0.00000

5.317 0.824 0.821 0.907 0.983 0.976 0.806

Mlig455_021500 {REF} {Length: 1309} {TRANSSPLICED} {Mouse: ENSMUSG00000040033, Stat2, signal transducer and activator of transcription 2, [RH, Score=71.2, Expect=2e-13]} {RNA1509_46464} {RNA1310_29059.1} {RNA815_22216}

Mlig455_063198 {REF} {Length: 1304} {TRANSSPLICED} {Mouse: ENSMUSG00000040033, Stat2, signal transducer and activator of transcription 2, [RH, Score=71.6, Expect=2e-13]} {RNA1509_29395, RNA1509_46464} {RNA1310_29059.1, RNA1509_29395, RNA1509_46464} {RNA1509_29395, RNA1509_46464, RNA815_22216}
3. MligTC455_20514 1263 26.31 Mlig455_008860

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.491/0.00005

Regeneration-upregulated BL: 1.687

Regeneration-enriched BL: 1.687

RPA1 5.078 0.826 0.856 0.790 0.867 0.956 0.783 Mlig455_008860 {REF} {Length: 2265} {TRANSSPLICED} {Pfam: Replication factor-A C terminal domain [PF08646.12, score=145.1]; Replication protein A OB domain [PF16900.7, score=113.7]; Replication factor-A protein 1, N-terminal domain [PF04057.14, score=63.4]; OB-fold nucleic acid binding domain [PF01336.27, score=53.1]; Cell division control protein 24, OB domain 3 [PF17244.4, score=31.4]} {Human: ENSG00000132383, RPA1, replication protein A1, [Score=456, Expect=2e-153]} {Mouse: ENSMUSG00000000751, Rpa1, replication protein A1, [Score=452, Expect=9e-152]} {Dmel: FBgn0010173, RpA-70, Replication Protein A 70, [Score=391, Expect=1e-128]} {Celegans: WBGene00017546, rpa-1, Probable replication factor A 73 kDa subunit, [Score=204, Expect=2e-57]} {Smed: dd_Smed_v6_3342_0_1, dd_Smed_v6_3342_0_1, [Score=399, Expect=1e-132]} {RNA1509_4117} {RNA1310_8147} {RNA815_2777}
4. MligTC455_22801 2268 47.24 Mlig455_021168, Mlig455_021214

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.394

Region-enriched R5: 1.393/0.00247

MCM7 5.05 0.891 0.763 0.858 0.954 0.714 0.870

Mlig455_021168 {REF} {Length: 3120} {Pfam: MCM P-loop domain [PF00493.25, score=325.4]; MCM OB domain [PF17207.5, score=119.3]; MCM AAA-lid domain [PF17855.3, score=73.6]; MCM N-terminal domain [PF14551.8, score=58.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=25.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=21.2]} {Human: ENSG00000166508, MCM7, minichromosome maintenance complex component 7, [RH, Score=868, Expect=0.0]} {Mouse: ENSMUSG00000029730, Mcm7, minichromosome maintenance complex component 7, [RH, Score=867, Expect=0.0]} {Dmel: FBgn0020633, Mcm7, Minichromosome maintenance 7, [RH, Score=828, Expect=0.0]} {Celegans: WBGene00003159, mcm-7, DNA helicase, [RH, Score=640, Expect=0.0]} {Smed: dd_Smed_v6_4712_0_1, dd_Smed_v6_4712_0_1, [RH, Score=723, Expect=0.0]} {RNA1509_14333, RNA1509_4791} {RNA1310_4893.2, RNA1509_14333, RNA1509_4791} {RNA1509_14333, RNA1509_4791, RNA815_1611}

Mlig455_021214 {REF} {Length: 3158} {Pfam: MCM P-loop domain [PF00493.25, score=325.4]; MCM OB domain [PF17207.5, score=119.3]; MCM AAA-lid domain [PF17855.3, score=73.6]; MCM N-terminal domain [PF14551.8, score=58.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=25.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=21.2]} {Human: ENSG00000166508, MCM7, minichromosome maintenance complex component 7, [RH, Score=868, Expect=0.0]} {Mouse: ENSMUSG00000029730, Mcm7, minichromosome maintenance complex component 7, [RH, Score=867, Expect=0.0]} {Dmel: FBgn0020633, Mcm7, Minichromosome maintenance 7, [RH, Score=828, Expect=0.0]} {Celegans: WBGene00003159, mcm-7, DNA helicase, [RH, Score=640, Expect=0.0]} {Smed: dd_Smed_v6_4712_0_1, dd_Smed_v6_4712_0_1, [RH, Score=723, Expect=0.0]} {RNA1509_4791} {RNA1310_4893.2} {RNA815_1611}
5. MligTC455_40013 1551 32.32 Mlig455_045254, Mlig455_069174

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.916/0.00000

Regeneration-upregulated BL: 1.957

Regeneration-enriched BL: 1.957

MCM5 5.018 0.901 0.717 0.736 0.965 0.851 0.848

Mlig455_045254 {REF} {Length: 2658} {Pfam: MCM P-loop domain [PF00493.25, score=329.8]; MCM OB domain [PF17207.5, score=115.3]; MCM AAA-lid domain [PF17855.3, score=92.5]; MCM N-terminal domain [PF14551.8, score=58.6]; Magnesium chelatase, subunit ChlI [PF01078.23, score=25.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.5]} {Human: ENSG00000100297, MCM5, minichromosome maintenance complex component 5, [RH, Score=937, Expect=0.0]} {Mouse: ENSMUSG00000005410, Mcm5, minichromosome maintenance complex component 5, [RH, Score=937, Expect=0.0]} {Dmel: FBgn0017577, Mcm5, Minichromosome maintenance 5, [RH, Score=892, Expect=0.0]} {Celegans: WBGene00003157, mcm-5, DNA replication licensing factor mcm-5, [RH, Score=800, Expect=0.0]} {Smed: dd_Smed_v6_5764_0_1, dd_Smed_v6_5764_0_1, [RH, Score=834, Expect=0.0]} {RNA1509_4580} {RNA1310_6377} {RNA815_5726}

Mlig455_069174 {REF} {Length: 3194} {Pfam: MCM P-loop domain [PF00493.25, score=329.3]; MCM OB domain [PF17207.5, score=114.9]; MCM AAA-lid domain [PF17855.3, score=92.4]; MCM N-terminal domain [PF14551.8, score=57.1]; Magnesium chelatase, subunit ChlI [PF01078.23, score=24.9]; Endonuclease-reverse transcriptase [PF14529.8, score=21.0]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.1]} {Human: ENSG00000100297, MCM5, minichromosome maintenance complex component 5, [RH, Score=932, Expect=0.0]} {Mouse: ENSMUSG00000005410, Mcm5, minichromosome maintenance complex component 5, [RH, Score=929, Expect=0.0]} {Dmel: FBgn0017577, Mcm5, Minichromosome maintenance 5, [RH, Score=890, Expect=0.0]} {Celegans: WBGene00003157, mcm-5, DNA replication licensing factor mcm-5, [RH, Score=803, Expect=0.0]} {Smed: dd_Smed_v6_5764_0_1, dd_Smed_v6_5764_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_4580} {RNA1310_6377} {RNA815_5726}
6. MligTC455_41079 459 9.56 Mlig455_031153

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.327/0.02031

CDC20 4.833 0.959 0.984 - 0.965 0.968 0.957 Mlig455_031153 {REF} {Length: 2273} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=47.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=43.4]} {Human: ENSG00000117399, CDC20, cell division cycle 20, [RH, Score=350, Expect=4e-114]} {Mouse: ENSMUSG00000006398, Cdc20, cell division cycle 20, [RH, Score=359, Expect=9e-118]} {Dmel: FBgn0001086, fzy, fizzy, [RH, Score=323, Expect=6e-104]} {Celegans: WBGene00001510, fzr-1, FiZzy Related family, [Score=261, Expect=4e-78]} {Smed: dd_Smed_v6_4796_0_1, dd_Smed_v6_4796_0_1, [Score=249, Expect=8e-76]} {RNA1509_30656} {RNA1310_10696} {RNA815_5941}
7. MligTC455_20988 1051 21.9 Mlig455_035963

Neo: Irradiation

Age: -

Region-enriched R5: 2.262/0.00002

4.606 0.896 - 0.969 0.954 0.903 0.884 Mlig455_035963 {REF} {Length: 1101} {TRANSSPLICED} {Pfam: Geminin [PF07412.14, score=23.7]} {RNA1509_12313, RNA1509_12547, RNA1509_20018} {RNA1310_31319, RNA1509_12313, RNA1509_12547, RNA1509_20018} {RNA1509_12313, RNA1509_12547, RNA1509_20018, RNA815_14142}
8. MligTC455_18863 8623 179.65 Mlig455_010017, Mlig455_010059, Mlig455_063261

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.339

Region-specific R5: 2.227

Region-enriched R5: 2.083/0.00000

Regeneration-upregulated BL: 1.438

Regeneration-enriched BL: 1.438

NASP 4.497 0.890 - 0.793 0.905 0.974 0.935

Mlig455_010017 {REF} {Length: 2233} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=21.6]; Tetratricopeptide repeat [PF13424.8, score=21.4]; SHNi-TPR [PF10516.11, score=18.9]} {Human: ENSG00000132780, NASP, nuclear autoantigenic sperm protein, [RH, Score=100, Expect=2e-21]} {Mouse: ENSMUSG00000028693, Nasp, nuclear autoantigenic sperm protein (histone-binding), [RH, Score=84.7, Expect=9e-17]} {Dmel: FBgn0037624, CG8223, [RH, Score=52.8, Expect=5e-07]} {Celegans: WBGene00008218, nasp-2, NASP (Human Nuclear Autoantigenic Sperm Protein) homolog, [Score=82.8, Expect=2e-16]} {Smed: dd_Smed_v6_5663_0_1, dd_Smed_v6_5663_0_1, [RH, Score=64.7, Expect=4e-11]} {RNA1509_11826} {RNA1310_10954.1} {RNA815_3729}

Mlig455_010059 {REF} {Length: 2238} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=21.5]; Tetratricopeptide repeat [PF13424.8, score=21.4]; SHNi-TPR [PF10516.11, score=18.9]} {Human: ENSG00000132780, NASP, nuclear autoantigenic sperm protein, [RH, Score=100, Expect=2e-21]} {Mouse: ENSMUSG00000028693, Nasp, nuclear autoantigenic sperm protein (histone-binding), [RH, Score=84.7, Expect=9e-17]} {Dmel: FBgn0037624, CG8223, [RH, Score=52.8, Expect=5e-07]} {Celegans: WBGene00008218, nasp-2, NASP (Human Nuclear Autoantigenic Sperm Protein) homolog, [Score=82.0, Expect=2e-16]} {Smed: dd_Smed_v6_5663_0_1, dd_Smed_v6_5663_0_1, [RH, Score=64.3, Expect=4e-11]} {RNA1509_11826, RNA1509_18948, RNA1509_40606} {RNA1310_10954.1, RNA1509_18948, RNA1509_40606} {RNA1509_18948, RNA1509_40606, RNA815_3729}

Mlig455_063261 {REF} {Length: 2234} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=21.6]; Tetratricopeptide repeat [PF13424.8, score=21.4]; SHNi-TPR [PF10516.11, score=18.9]} {Human: ENSG00000132780, NASP, nuclear autoantigenic sperm protein, [RH, Score=100, Expect=2e-21]} {Mouse: ENSMUSG00000028693, Nasp, nuclear autoantigenic sperm protein (histone-binding), [RH, Score=84.7, Expect=9e-17]} {Dmel: FBgn0037624, CG8223, [RH, Score=52.8, Expect=5e-07]} {Celegans: WBGene00008218, nasp-2, NASP (Human Nuclear Autoantigenic Sperm Protein) homolog, [Score=82.8, Expect=2e-16]} {Smed: dd_Smed_v6_5663_0_1, dd_Smed_v6_5663_0_1, [RH, Score=64.7, Expect=4e-11]} {RNA1509_10809, RNA1509_11826, RNA1509_18556, RNA1509_2636, RNA1509_45053, RNA1509_8122} {RNA1310_10954.1, RNA1509_10809, RNA1509_11826, RNA1509_18556, RNA1509_2636, RNA1509_45053, RNA1509_8122} {RNA1509_10809, RNA1509_11826, RNA1509_18556, RNA1509_2636, RNA1509_45053, RNA1509_8122, RNA815_3729}
9. MligTC455_51175 916 19.08 Mlig455_024766, Mlig455_066113

Neo: Irradiation

Age: -

Region-enriched R5: 2.458/0.00000

WEE2 4.389 0.933 0.931 0.964 - 0.766 0.795

Mlig455_024766 {REF} {Length: 2438} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=107.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=69.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=20.0]} {Human: ENSG00000263042, WEE2, WEE1 homolog 2, [Score=112, Expect=9e-26]; ENSG00000214102, WEE2, WEE1 homolog 2, [Score=112, Expect=9e-26]} {Mouse: ENSMUSG00000037159, Wee2, WEE1 homolog 2 (S. pombe), [RH, Score=117, Expect=2e-27]} {Dmel: FBgn0011737, Wee1, Wee1 kinase, [RH, Score=115, Expect=9e-27]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=75.1, Expect=7e-14]} {Smed: dd_Smed_v6_17244_0_1, dd_Smed_v6_17244_0_1, [Score=83.6, Expect=6e-17]} {RNA1509_41627, RNA1509_55110} {RNA1310_9033, RNA1509_41627} {RNA1509_41627, RNA815_4229.1}

Mlig455_066113 {REF} {Length: 2412} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=90.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=60.1]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=20.0]} {Human: ENSG00000263042, WEE2, WEE1 homolog 2, [Score=100, Expect=9e-22]; ENSG00000214102, WEE2, WEE1 homolog 2, [Score=100, Expect=9e-22]} {Mouse: ENSMUSG00000037159, Wee2, WEE1 homolog 2 (S. pombe), [Score=103, Expect=5e-23]} {Dmel: FBgn0040298, Myt1, [Score=83.6, Expect=1e-16]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=62.4, Expect=5e-10]} {Smed: dd_Smed_v6_12461_0_1, dd_Smed_v6_12461_0_1, [Score=73.2, Expect=5e-14]} {RNA1509_55110} {RNA1310_9033} {RNA815_4229.1}
10. MligTC455_47882 920 19.18 Mlig455_014428

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.468/0.00366
Region-enriched R5: 1.389/0.00012

4.299 0.770 0.807 0.856 0.906 0.960 - Mlig455_014428 {REF} {Length: 914} {TRANSSPLICED} {RNA1509_12311} {RNA1310_13342} {RNA815_9722.1}
11. MligTC455_43592 956 19.92 Mlig455_015053

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.464/0.00058

CDK1 3.462 - - 0.826 0.964 0.877 0.795 Mlig455_015053 {REF} {Length: 1680} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=253.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=124.7]; Haspin like kinase domain [PF12330.10, score=23.8]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.0]} {Human: ENSG00000170312, CDK1, cyclin dependent kinase 1, [RH, Score=412, Expect=6e-145]} {Mouse: ENSMUSG00000019942, Cdk1, cyclin-dependent kinase 1, [RH, Score=407, Expect=3e-143]} {Dmel: FBgn0004106, Cdk1, Cyclin-dependent kinase 1, [RH, Score=418, Expect=8e-148]} {Celegans: WBGene00000405, cdk-1, Cyclin-dependent kinase 1, [RH, Score=400, Expect=3e-140]} {Smed: dd_Smed_v6_31502_0_2, dd_Smed_v6_31502_0_2, [RH, Score=412, Expect=5e-145]} {RNA1509_21595, RNA1509_7104} {RNA1310_17831, RNA1509_21595, RNA1509_7104} {RNA1509_21595, RNA1509_7104, RNA815_7489.1}
12. MligTC455_39646 934 19.46 Mlig455_021914

Neo: Neoblast, stringent

Age: Down-Up-Up, logFC(26M/2M)=0.293

SF3A3 3.443 0.823 - - 0.879 0.967 0.774 Mlig455_021914 {REF} {Length: 1804} {TRANSSPLICED} {Pfam: SF3a60/Prp9 C-terminal [PF11931.10, score=144.3]} {Human: ENSG00000183431, SF3A3, splicing factor 3a subunit 3, [Score=243, Expect=9e-77]} {Mouse: ENSMUSG00000028902, Sf3a3, splicing factor 3a, subunit 3, [Score=243, Expect=3e-77]} {Dmel: FBgn0014366, noi, noisette, [Score=253, Expect=9e-81]} {Celegans: WBGene00011758, T13H5.4, [Score=206, Expect=3e-63]} {Smed: dd_Smed_v6_2653_0_1, dd_Smed_v6_2653_0_1, [Score=207, Expect=3e-63]} {RNA1509_27195} {RNA1310_12410} {RNA815_13038}
13. MligTC455_39647 1875 39.07 Mlig455_021993, Mlig455_022046

Neo: -

Age: logFC(26M/2M)=0.652

SF3A3 3.423 0.823 - - 0.861 0.969 0.770

Mlig455_021993 {REF} {Length: 1884} {TRANSSPLICED} {Pfam: SF3a60/Prp9 C-terminal [PF11931.10, score=183.7]; Replication stress response SDE2 C-terminal [PF13297.8, score=96.5]; Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 [PF16837.7, score=60.7]; Splicing factor SF3a60 binding domain [PF12108.10, score=28.6]} {Human: ENSG00000183431, SF3A3, splicing factor 3a subunit 3, [RH, Score=629, Expect=0.0]} {Mouse: ENSMUSG00000028902, Sf3a3, splicing factor 3a, subunit 3, [RH, Score=628, Expect=0.0]} {Dmel: FBgn0014366, noi, noisette, [RH, Score=609, Expect=0.0]} {Celegans: WBGene00011758, T13H5.4, [RH, Score=524, Expect=0.0]} {Smed: dd_Smed_v6_2653_0_1, dd_Smed_v6_2653_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_27195} {RNA1310_12410} {RNA815_13038}

Mlig455_022046 {REF} {Length: 1884} {TRANSSPLICED} {Pfam: SF3a60/Prp9 C-terminal [PF11931.10, score=183.7]; Replication stress response SDE2 C-terminal [PF13297.8, score=96.5]; Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 [PF16837.7, score=60.7]; Splicing factor SF3a60 binding domain [PF12108.10, score=28.6]} {Human: ENSG00000183431, SF3A3, splicing factor 3a subunit 3, [RH, Score=629, Expect=0.0]} {Mouse: ENSMUSG00000028902, Sf3a3, splicing factor 3a, subunit 3, [RH, Score=628, Expect=0.0]} {Dmel: FBgn0014366, noi, noisette, [RH, Score=609, Expect=0.0]} {Celegans: WBGene00011758, T13H5.4, [RH, Score=524, Expect=0.0]} {Smed: dd_Smed_v6_2653_0_1, dd_Smed_v6_2653_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_26009, RNA1509_27195, RNA1509_35084, RNA1509_58691, RNA1509_9315} {RNA1310_12410, RNA1509_26009, RNA1509_27195, RNA1509_35084, RNA1509_58691, RNA1509_9315} {RNA1509_26009, RNA1509_27195, RNA1509_35084, RNA1509_58691, RNA1509_9315, RNA815_13038}
14. MligTC455_22802 375 7.81 Mlig455_057869

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.211

Region-enriched R5: 2.321/0.00758

MCM7 3.392 0.754 - 0.814 0.963 - 0.861 Mlig455_057869 {REF} {Length: 3104} {Pfam: MCM P-loop domain [PF00493.25, score=325.4]; MCM OB domain [PF17207.5, score=119.7]; MCM AAA-lid domain [PF17855.3, score=73.6]; MCM N-terminal domain [PF14551.8, score=58.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=25.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=21.2]} {Human: ENSG00000166508, MCM7, minichromosome maintenance complex component 7, [RH, Score=868, Expect=0.0]} {Mouse: ENSMUSG00000029730, Mcm7, minichromosome maintenance complex component 7, [RH, Score=866, Expect=0.0]} {Dmel: FBgn0020633, Mcm7, Minichromosome maintenance 7, [RH, Score=829, Expect=0.0]} {Celegans: WBGene00003159, mcm-7, DNA helicase, [RH, Score=639, Expect=0.0]} {Smed: dd_Smed_v6_4712_0_1, dd_Smed_v6_4712_0_1, [RH, Score=724, Expect=0.0]} {RNA1509_14333} {RNA1310_4893.2} {RNA815_1611}
15. MligTC455_27656 14970 311.88 Mlig455_017241

Neo: Int S/G2/M

Age: -

TUBA1A 3.276 0.762 - 0.812 - 0.733 0.969 Mlig455_017241 {REF} {Length: 2280} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=230.6]; Tubulin C-terminal domain [PF03953.19, score=177.9]; Tubulin domain [PF14881.8, score=18.7]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [RH, Score=937, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [RH, Score=934, Expect=0.0]; ENSG00000075886, TUBA3D, tubulin alpha 3d, [RH, Score=927, Expect=0.0]; ENSG00000198033, TUBA3C, tubulin alpha 3c, [RH, Score=927, Expect=0.0]; ENSG00000152086, TUBA3E, tubulin alpha 3e, [RH, Score=911, Expect=0.0]; ENSG00000167553, TUBA1C, tubulin alpha 1c, [RH, Score=891, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [RH, Score=937, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [RH, Score=934, Expect=0.0]; ENSMUSG00000067702, Tuba3a, tubulin, alpha 3A, [RH, Score=927, Expect=0.0]; ENSMUSG00000067338, Tuba3b, tubulin, alpha 3B, [RH, Score=927, Expect=0.0]; ENSMUSG00000043091, Tuba1c, tubulin, alpha 1C, [RH, Score=919, Expect=0.0]} {Dmel: FBgn0003884, alphaTub84B, alpha-Tubulin at 84B, [RH, Score=922, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [RH, Score=858, Expect=0.0]} {Smed: dd_Smed_v6_10947_0_2, dd_Smed_v6_10947_0_2, [RH, Score=934, Expect=0.0]} {RNA1509_13953, RNA1509_14976, RNA1509_37193, RNA1509_43271, RNA1509_49156, RNA1509_8064, RNA1509_8722} {RNA1310_10339.1, RNA1509_13953, RNA1509_14976, RNA1509_37193, RNA1509_49156, RNA1509_8064, RNA1509_8722} {RNA1509_13953, RNA1509_14976, RNA1509_37193, RNA1509_49156, RNA1509_8064, RNA1509_8722, RNA815_1715.2}
16. MligTC455_34361 4426 92.21 Mlig455_025291, Mlig455_025317

Neo: Neoblast, stringent

Age: Down-Up-Down

Region-enriched R5: 1.390/0.00001

PCNA 2.636 0.824 - - 0.954 - 0.858

Mlig455_025291 {REF} {Length: 1283} {TRANSSPLICED} {Pfam: Proliferating cell nuclear antigen, N-terminal domain [PF00705.20, score=180.6]; Proliferating cell nuclear antigen, C-terminal domain [PF02747.17, score=176.9]; Rad9 [PF04139.15, score=39.8]; Repair protein Rad1/Rec1/Rad17 [PF02144.18, score=28.2]; Hus1-like protein [PF04005.14, score=19.8]} {Human: ENSG00000132646, PCNA, proliferating cell nuclear antigen, [RH, Score=359, Expect=8e-126]} {Mouse: ENSMUSG00000027342, Pcna, proliferating cell nuclear antigen, [RH, Score=360, Expect=2e-126]; ENSMUSG00000067608, Pcna-ps2, proliferating cell nuclear antigen pseudogene 2, [RH, Score=360, Expect=1e-126]} {Dmel: FBgn0005655, PCNA, Proliferating cell nuclear antigen, [RH, Score=348, Expect=1e-121]} {Celegans: WBGene00003955, pcn-1, Proliferating cell nuclear antigen, [RH, Score=259, Expect=7e-87]} {Smed: dd_Smed_v6_1920_0_1, dd_Smed_v6_1920_0_1, [RH, Score=373, Expect=9e-132]} {RNA1509_20905} {RNA1310_24951.1} {RNA815_11580.1}

Mlig455_025317 {REF} {Length: 1281} {TRANSSPLICED} {Pfam: Proliferating cell nuclear antigen, N-terminal domain [PF00705.20, score=180.6]; Proliferating cell nuclear antigen, C-terminal domain [PF02747.17, score=176.9]; Rad9 [PF04139.15, score=39.8]; Repair protein Rad1/Rec1/Rad17 [PF02144.18, score=28.2]; Hus1-like protein [PF04005.14, score=19.8]} {Human: ENSG00000132646, PCNA, proliferating cell nuclear antigen, [RH, Score=359, Expect=8e-126]} {Mouse: ENSMUSG00000027342, Pcna, proliferating cell nuclear antigen, [RH, Score=360, Expect=2e-126]; ENSMUSG00000067608, Pcna-ps2, proliferating cell nuclear antigen pseudogene 2, [RH, Score=360, Expect=1e-126]} {Dmel: FBgn0005655, PCNA, Proliferating cell nuclear antigen, [RH, Score=348, Expect=1e-121]} {Celegans: WBGene00003955, pcn-1, Proliferating cell nuclear antigen, [RH, Score=259, Expect=7e-87]} {Smed: dd_Smed_v6_1920_0_1, dd_Smed_v6_1920_0_1, [RH, Score=373, Expect=9e-132]} {RNA1509_20905} {RNA1310_24951.1} {RNA815_11580.1}
17. MligTC455_44415 647 13.48 Mlig455_055865

Neo: Neoblast, stringent

Age: -

Region-enriched R4: 1.289/0.02633
Region-enriched R5: 1.282/0.00357

Regeneration-enriched TP: 2.914
Regeneration-enriched R6: 1.955

TOP2A 2.611 - 0.821 0.839 0.951 - - Mlig455_055865 {REF} {Length: 5444} {TRANSSPLICED} {Pfam: DNA gyrase/topoisomerase IV, subunit A [PF00521.22, score=407.8]; C-terminal associated domain of TOPRIM [PF16898.7, score=149.4]; DNA gyrase B [PF00204.27, score=73.4]; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase [PF02518.28, score=57.3]; Toprim domain [PF01751.24, score=33.1]} {Human: ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=1315, Expect=0.0]; ENSG00000077097, TOP2B, DNA topoisomerase II beta, [Score=1300, Expect=0.0]} {Mouse: ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=1325, Expect=0.0]; ENSMUSG00000017485, Top2b, topoisomerase (DNA) II beta, [Score=1295, Expect=0.0]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=1228, Expect=0.0]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=1202, Expect=0.0]} {Smed: dd_Smed_v6_1626_0_2, dd_Smed_v6_1626_0_2, [Score=1207, Expect=0.0]} {RNA1509_2428} {RNA1310_1442, RNA1509_2428} {RNA1509_2428, RNA815_409}
18. MligTC455_42529 1053 21.93 Mlig455_050818

Neo: Irradiation

Age: logFC(26M/2M)=0.320

Region-specific R5: 4.061

Region-enriched R5: 3.801/0.00000
Region-enriched R6: 2.361/0.00459

2.589 0.928 - 0.958 - - 0.703 Mlig455_050818 {REF} {Length: 1422} {TRANSSPLICED} {RNA1509_10427, RNA1509_20462, RNA1509_24340} {RNA1310_21686, RNA1509_10427, RNA1509_20462, RNA1509_24340} {RNA1509_10427, RNA1509_20462, RNA1509_24340, RNA815_8467.1}
19. MligTC455_41170 965 20.1 Mlig455_009941, Mlig455_035110

Neo: Int S/G2/M

Age: -

Region-enriched R4: 2.081/0.00955

RBBP8 2.571 0.753 - 0.973 - 0.845 -

Mlig455_009941 {REF} {Length: 1805} {TRANSSPLICED} {Pfam: SlyX [PF04102.14, score=21.0]} {Human: ENSG00000101773, RBBP8, RB binding protein 8, endonuclease, [RH, Score=59.7, Expect=8e-09]} {Mouse: ENSMUSG00000041238, Rbbp8, retinoblastoma binding protein 8, endonuclease, [RH, Score=60.1, Expect=4e-09]} {RNA1509_16493, RNA1509_44203} {RNA1310_16256.1, RNA1509_44203} {RNA1509_44203, RNA815_6106.1}

Mlig455_035110 {REF} {Length: 1804} {TRANSSPLICED} {Pfam: SlyX [PF04102.14, score=21.0]} {Human: ENSG00000101773, RBBP8, RB binding protein 8, endonuclease, [RH, Score=59.7, Expect=7e-09]} {Mouse: ENSMUSG00000041238, Rbbp8, retinoblastoma binding protein 8, endonuclease, [RH, Score=60.1, Expect=4e-09]} {RNA1509_16493} {RNA1310_16256.1, RNA1509_16493} {RNA1509_16493, RNA815_6106.1}
20. MligTC455_41171 479 9.99 Mlig455_062420

Neo: -

Age: -

Region-enriched R4: 1.846/0.02223
Region-enriched R5: 1.199/0.04594

RBBP8 2.546 0.727 - 0.976 - 0.843 - Mlig455_062420 {REF} {Length: 1025} {TRANSSPLICED} {Pfam: SlyX [PF04102.14, score=21.0]} {Human: ENSG00000101773, RBBP8, RB binding protein 8, endonuclease, [RH, Score=59.7, Expect=8e-09]} {Mouse: ENSMUSG00000041238, Rbbp8, retinoblastoma binding protein 8, endonuclease, [RH, Score=60.1, Expect=4e-09]} {RNA1509_44203} {RNA1310_16256.1} {RNA815_6106.1}
21. MligTC455_42441 943 19.65 Mlig455_067966

Neo: Neoblast, stringent

Age: -

BUB1B 2.536 - - 0.807 0.972 0.757 - Mlig455_067966 {REF} {Length: 4977} {Pfam: Mad3/BUB1 homology region 1 [PF08311.14, score=116.8]; Protein kinase domain [PF00069.27, score=31.3]} {Human: ENSG00000156970, BUB1B, BUB1 mitotic checkpoint serine/threonine kinase B, [Score=118, Expect=3e-26]} {Mouse: ENSMUSG00000027379, Bub1, BUB1, mitotic checkpoint serine/threonine kinase, [RH, Score=112, Expect=2e-24]} {Dmel: FBgn0031696, Bub1, Bub1 kinase, [RH, Score=103, Expect=1e-21]} {Celegans: WBGene00000275, bub-1, Mitotic checkpoint serine/threonine-protein kinase bub-1, [RH, Score=71.2, Expect=4e-12]} {Smed: dd_Smed_v6_5366_0_2, dd_Smed_v6_5366_0_2, [Score=50.4, Expect=3e-07]} {RNA1509_9302} {RNA1310_672.1} {RNA815_6919}
22. MligTC455_31157 663 13.81 Mlig455_049596

Neo: Neoblast, stringent

Age: Down-Up-Up

Region-enriched R5: 2.154/0.00000

2.523 0.785 0.771 0.967 - - - Mlig455_049596 {REF} {Length: 788} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF1761) [PF08570.12, score=41.3]} {RNA1509_39908} {RNA1310_45121, RNA1509_39908} {RNA1509_39908, RNA815_26658}
23. MligTC455_21321 3262 67.96 Mlig455_020289

Neo: Int S/G2/M

Age: Down-Down-Up

Region-enriched R5: 1.162/0.00000

TMX1 2.517 - 0.744 - 0.817 0.956 - Mlig455_020289 {REF} {Length: 3720} {TRANSSPLICED} {Pfam: Thioredoxin [PF00085.22, score=63.3]} {Human: ENSG00000139921, TMX1, thioredoxin related transmembrane protein 1, [RH, Score=145, Expect=2e-41]} {Mouse: ENSMUSG00000021072, Tmx1, thioredoxin-related transmembrane protein 1, [RH, Score=144, Expect=2e-41]} {Dmel: FBgn0034914, CG5554, [RH, Score=153, Expect=2e-44]} {Celegans: WBGene00001073, dpy-11, DumPY: shorter than wild-type; Thioredoxin-like protein DPY-11, [RH, Score=137, Expect=3e-39]} {Smed: dd_Smed_v6_10003_0_1, dd_Smed_v6_10003_0_1, [Score=73.6, Expect=8e-15]} {RNA1509_18453, RNA1509_28629, RNA1509_38564} {RNA1310_29016.1, RNA1509_18453, RNA1509_28629, RNA1509_38564} {RNA1509_18453, RNA1509_28629, RNA1509_38564, RNA815_12579}
24. MligTC455_20515 1058 22.04 Mlig455_008959

Neo: Irradiation

Age: -

Region-enriched R5: 1.041/0.01884

RPA1 2.485 - 0.725 - 0.971 - 0.789 Mlig455_008959 {REF} {Length: 2367} {TRANSSPLICED} {Pfam: Replication factor-A C terminal domain [PF08646.12, score=154.5]; Replication protein A OB domain [PF16900.7, score=113.5]; Replication factor-A protein 1, N-terminal domain [PF04057.14, score=63.1]; OB-fold nucleic acid binding domain [PF01336.27, score=53.2]; Cell division control protein 24, OB domain 3 [PF17244.4, score=28.5]} {Human: ENSG00000132383, RPA1, replication protein A1, [RH, Score=496, Expect=1e-168]} {Mouse: ENSMUSG00000000751, Rpa1, replication protein A1, [RH, Score=496, Expect=2e-168]} {Dmel: FBgn0010173, RpA-70, Replication Protein A 70, [RH, Score=434, Expect=9e-145]} {Celegans: WBGene00017546, rpa-1, Probable replication factor A 73 kDa subunit, [RH, Score=217, Expect=1e-61]} {Smed: dd_Smed_v6_3342_0_1, dd_Smed_v6_3342_0_1, [RH, Score=416, Expect=1e-138]} {RNA1509_35290, RNA1509_4117, RNA1509_54395} {RNA1310_7820.1, RNA1509_35290, RNA1509_4117, RNA1509_54395} {RNA1509_35290, RNA1509_4117, RNA1509_54395, RNA815_2777}
25. MligTC455_20666 432 8.99 Mlig455_031251

Neo: Irradiation

Age: -

Region-enriched R5: 1.274/0.00795

XPC 2.473 - - 0.742 0.969 - 0.762 Mlig455_031251 {REF} {Length: 7201} {TRANSSPLICED} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=83.9]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=52.6]; Rad4 transglutaminase-like domain [PF03835.17, score=50.3]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=293, Expect=1e-84]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=301, Expect=1e-87]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=295, Expect=1e-83]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=228, Expect=1e-61]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=237, Expect=2e-67]} {RNA1509_37174} {RNA1310_2636} {RNA815_7190.1}
26. MligTC455_20667 992 20.67 Mlig455_031254, Mlig455_031299, Mlig455_031329

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.264

Region-enriched R5: 1.345/0.00244

XPC 2.434 - - 0.720 0.958 - 0.756

Mlig455_031254 {REF} {Length: 234} {NoTransDecoderORF} {RNA1509_41875} {RNA1310_5347}

Mlig455_031299 {REF} {Length: 5228} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=85.1]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=54.1]; Rad4 transglutaminase-like domain [PF03835.17, score=50.1]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=292, Expect=5e-84]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=302, Expect=6e-88]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=296, Expect=3e-84]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=231, Expect=1e-62]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=236, Expect=3e-67]} {RNA1509_22240, RNA1509_37174, RNA1509_43141} {RNA1310_2636, RNA1509_22240, RNA1509_37174, RNA1509_43141} {RNA1509_22240, RNA1509_37174, RNA1509_43141, RNA815_7190.1}

Mlig455_031329 {REF} {Length: 3756} {TRANSSPLICED} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=84.0]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=52.6]; Rad4 transglutaminase-like domain [PF03835.17, score=50.2]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=283, Expect=5e-81]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=301, Expect=9e-88]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=296, Expect=2e-84]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=229, Expect=3e-62]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=237, Expect=2e-67]} {RNA1509_38140} {RNA1310_4273.2} {RNA815_7190.1}
27. MligTC455_42528 974 20.3 Mlig455_043278

Neo: -

Age: -

Region-specific R5: 4.050

Region-enriched R5: 3.762/0.00000
Region-enriched R6: 2.423/0.00223

1.885 0.923 - 0.962 - - - Mlig455_043278 {REF} {Length: 1530} {TRANSSPLICED} {RNA1509_24340, RNA1509_36228} {RNA1310_19693, RNA1509_36228} {RNA1509_36228, RNA815_8467.1}
28. MligTC455_39433 348 7.25 Mlig455_067841

Neo: -

Age: Down-Up-Up

Region-enriched R4: 3.187/0.00988
Region-enriched R5: 3.060/0.00036

EXOSC8 1.873 - - - 0.951 0.922 - Mlig455_067841 {REF} {Length: 1741} {TRANSSPLICED} {Pfam: 3' exoribonuclease family, domain 1 [PF01138.23, score=65.0]} {Human: ENSG00000120699, EXOSC8, exosome component 8, [RH, Score=99.4, Expect=9e-24]} {Mouse: ENSMUSG00000027752, Exosc8, exosome component 8, [RH, Score=94.4, Expect=4e-22]} {RNA1509_38958} {RNA1310_20971, RNA1509_38958} {RNA1509_38958, RNA815_18350}
29. MligTC455_27555 571 11.89 Mlig455_045152

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.234

Region-enriched R5: 1.064/0.00881

MPHOSPH8 1.812 - - - 0.956 0.856 - Mlig455_045152 {REF} {Length: 2584} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=43.2]; Chromo (CHRromatin Organisation MOdifier) domain [PF00385.26, score=38.9]; Ankyrin repeat [PF13606.8, score=29.3]; Ankyrin repeats (many copies) [PF13857.8, score=27.3]; Ankyrin repeats (many copies) [PF13637.8, score=26.3]; Ankyrin repeat [PF00023.32, score=23.7]} {Human: ENSG00000196199, MPHOSPH8, M-phase phosphoprotein 8, [Score=59.3, Expect=2e-08]} {Mouse: ENSMUSG00000079184, Mphosph8, M-phase phosphoprotein 8, [Score=62.0, Expect=2e-09]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=51.6, Expect=2e-06]} {Smed: dd_Smed_v6_10984_0_1, dd_Smed_v6_10984_0_1, [Score=55.5, Expect=9e-08]} {RNA1509_11349} {RNA1310_8020, RNA1509_11349} {RNA1509_11349, RNA815_18069}
30. MligTC455_16889 554 11.53 Mlig455_017176

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.299

Region-enriched R5: 1.228/0.00051

1.804 - - - 0.960 0.844 - Mlig455_017176 {REF} {Length: 1431} {TRANSSPLICED} {Pfam: Transmembrane protein 126 [PF07114.13, score=30.6]} {Smed: dd_Smed_v6_6959_0_1, dd_Smed_v6_6959_0_1, [RH, Score=75.1, Expect=4e-16]} {RNA1509_25056} {RNA1310_22789, RNA1509_25056} {RNA1509_25056, RNA815_9908}
31. MligTC455_14018 2828 58.91 Mlig455_037706, Mlig455_046368, Mlig455_046398

Neo: Neoblast

Age: -

UTP4 1.777 - - - 0.819 0.958 -

Mlig455_037706 {REF} {Length: 4818} {TRANSSPLICED} {Pfam: ssDNA-binding domain of telomere protection protein [PF16686.7, score=50.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=23.2]} {Human: ENSG00000141076, UTP4, UTP4, small subunit processome component, [RH, Score=198, Expect=3e-52]} {Mouse: ENSMUSG00000041438, Utp4, UTP4 small subunit processome component, [RH, Score=193, Expect=9e-51]} {Dmel: FBgn0263605, l(3)72Dn, lethal (3) 72Dn, [RH, Score=129, Expect=4e-30]} {Celegans: WBGene00010582, K05C4.5, [RH, Score=61.6, Expect=4e-09]} {Smed: dd_Smed_v6_9398_0_1, dd_Smed_v6_9398_0_1, [RH, Score=69.7, Expect=1e-11]} {RNA1509_3993} {RNA1310_6031} {RNA815_7026}

Mlig455_046368 {REF} {Length: 2900} {TRANSSPLICED} {Pfam: Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=27.3]} {Human: ENSG00000141076, UTP4, UTP4, small subunit processome component, [RH, Score=198, Expect=4e-53]} {Mouse: ENSMUSG00000041438, Utp4, UTP4 small subunit processome component, [RH, Score=193, Expect=1e-51]} {Dmel: FBgn0263605, l(3)72Dn, lethal (3) 72Dn, [RH, Score=129, Expect=1e-30]} {Celegans: WBGene00010582, K05C4.5, [RH, Score=63.9, Expect=3e-10]} {Smed: dd_Smed_v6_9398_0_1, dd_Smed_v6_9398_0_1, [RH, Score=68.9, Expect=9e-12]} {RNA1509_3993} {RNA1310_6031} {RNA815_7026}

Mlig455_046398 {REF} {Length: 3844} {TRANSSPLICED} {Pfam: Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=27.3]} {Human: ENSG00000141076, UTP4, UTP4, small subunit processome component, [RH, Score=198, Expect=4e-53]} {Mouse: ENSMUSG00000041438, Utp4, UTP4 small subunit processome component, [RH, Score=193, Expect=1e-51]} {Dmel: FBgn0263605, l(3)72Dn, lethal (3) 72Dn, [RH, Score=129, Expect=1e-30]} {Celegans: WBGene00010582, K05C4.5, [RH, Score=63.9, Expect=3e-10]} {Smed: dd_Smed_v6_9398_0_1, dd_Smed_v6_9398_0_1, [RH, Score=68.9, Expect=9e-12]} {RNA1509_3993} {RNA1310_6031} {RNA815_7026}
32. MligTC455_39304 407 8.48 Mlig455_052114

Neo: Irradiation

Age: logFC(26M/2M)=0.322

Region-enriched R5: 1.796/0.00005

WRN 1.729 0.775 - 0.954 - - - Mlig455_052114 {REF} {Length: 2453} {Pfam: 3'-5' exonuclease [PF01612.22, score=54.4]} {Human: ENSG00000165392, WRN, Werner syndrome RecQ like helicase, [Score=99.8, Expect=5e-22]} {Mouse: ENSMUSG00000031583, Wrn, Werner syndrome RecQ like helicase, [Score=107, Expect=1e-24]} {Dmel: FBgn0038608, WRNexo, WRN exonuclease, [RH, Score=71.2, Expect=2e-13]} {Smed: dd_Smed_v6_16426_0_1, dd_Smed_v6_16426_0_1, [Score=74.3, Expect=2e-15]} {RNA1509_27014} {RNA1310_23821} {RNA815_9976.1}
33. MligTC455_50460 232 4.84 Mlig455_050167

Neo: Int S/G2/M

Age: -

Region-enriched R4: 2.509/0.04734

1.715 - - 0.737 0.978 - - Mlig455_050167 {REF} {Length: 2260} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=38.4]} {RNA1509_32778, RNA1509_44082, RNA1509_44517} {RNA1310_38674, RNA1509_44082, RNA1509_44517} {RNA1509_44082, RNA1509_44517, RNA815_25642}
34. MligTC455_21095 2187 45.56 Mlig455_045173

Neo: -

Age: -

Region-enriched R4: 1.126/0.01219
Region-enriched R5: 1.067/0.00188

1.703 0.734 - - - 0.969 - Mlig455_045173 {REF} {Length: 1194} {TRANSSPLICED} {Pfam: Hydrolethalus syndrome protein 1 C-terminus [PF15311.8, score=36.9]} {Smed: dd_Smed_v6_13289_0_1, dd_Smed_v6_13289_0_1, [RH, Score=84.0, Expect=5e-19]} {RNA1509_20356, RNA1509_2304} {RNA1310_28845, RNA1509_20356, RNA1509_2304} {RNA1509_20356, RNA1509_2304, RNA815_27698}
35. MligTC455_33133 546 11.36 Mlig455_061682

Neo: Neoblast, stringent

Age: -

DNAJC9 1.701 0.737 - - 0.964 - - Mlig455_061682 {REF} {Length: 2434} {TRANSSPLICED} {Pfam: DnaJ domain [PF00226.33, score=71.7]} {Human: ENSG00000213551, DNAJC9, DnaJ heat shock protein family (Hsp40) member C9, [RH, Score=197, Expect=1e-61]} {Mouse: ENSMUSG00000021811, Dnajc9, DnaJ heat shock protein family (Hsp40) member C9, [RH, Score=199, Expect=3e-62]} {Dmel: FBgn0037878, CG6693, [RH, Score=168, Expect=4e-50]} {Celegans: WBGene00001041, dnj-23, DNaJ domain (Prokaryotic heat shock protein), [RH, Score=140, Expect=2e-40]} {Smed: dd_Smed_v6_7703_0_1, dd_Smed_v6_7703_0_1, [RH, Score=155, Expect=5e-46]} {RNA1509_13475, RNA1509_28841} {RNA1310_18119, RNA1509_28841} {RNA1509_28841, RNA815_4493}
36. MligTC455_43989 261 5.45 Mlig455_049461

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.699/0.02653

RPP25L 1.695 - - 0.745 0.950 - - Mlig455_049461 {REF} {Length: 1676} {TRANSSPLICED} {Pfam: Alba [PF01918.23, score=27.8]} {Human: ENSG00000164967, RPP25L, ribonuclease P/MRP subunit p25 like, [RH, Score=58.2, Expect=4e-10]} {Mouse: ENSMUSG00000036114, Rpp25l, ribonuclease P/MRP 25 subunit-like, [RH, Score=55.1, Expect=3e-09]} {Smed: dd_Smed_v6_16418_0_1, dd_Smed_v6_16418_0_1, [RH, Score=67.0, Expect=8e-14]} {RNA1509_36835} {RNA1310_27908, RNA1509_36835} {RNA1509_36835, RNA815_329.1}
37. MligTC455_39190 323 6.72 Mlig455_026588

Neo: Int S/G2/M

Age: Down-Up-Down

Region-enriched R5: 1.318/0.02368

FEN1 1.676 - 0.724 - 0.952 - - Mlig455_026588 {REF} {Length: 2905} {Pfam: XPG N-terminal domain [PF00752.19, score=105.5]; XPG I-region [PF00867.20, score=101.3]; 5'-3' exonuclease, C-terminal SAM fold [PF01367.22, score=34.7]} {Human: ENSG00000168496, FEN1, flap structure-specific endonuclease 1, [RH, Score=461, Expect=1e-161]} {Mouse: ENSMUSG00000024742, Fen1, flap structure specific endonuclease 1, [RH, Score=476, Expect=1e-167]} {Dmel: FBgn0025832, Fen1, Flap endonuclease 1, [RH, Score=465, Expect=2e-163]} {Celegans: WBGene00000794, crn-1, Flap endonuclease 1, [RH, Score=438, Expect=4e-153]} {Smed: dd_Smed_v6_8206_0_1, dd_Smed_v6_8206_0_1, [RH, Score=469, Expect=2e-165]} {RNA1509_43574, RNA1509_54653} {RNA1310_13213.1, RNA1509_43574, RNA1509_54653} {RNA1509_43574, RNA1509_54653, RNA815_9256}
38. MligTC455_26895 197 4.1 Mlig455_013036

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.303

Region-enriched R4: 5.042/0.00003
Region-enriched R5: 3.848/0.00004
Region-enriched R6: 3.112/0.01142

1.674 - - 0.714 0.960 - - Mlig455_013036 {REF} {Length: 2567} {RNA1509_16883} {RNA1310_7853.1} {RNA815_5910}
39. MligTC455_26894 254 5.29 Mlig455_013003

Neo: -

Age: -

Region-enriched R4: 4.231/0.00003
Region-enriched R5: 3.493/0.00001
Region-enriched R6: 2.802/0.00935

1.673 - - 0.723 0.950 - - Mlig455_013003 {REF} {Length: 782} {RNA1509_35352} {RNA1310_7853.1} {RNA815_5910}
40. MligTC455_40984 1735 36.14 Mlig455_011431, Mlig455_061173

Neo: Neoblast

Age: -

PLAA 0.967 - - - 0.967 - -

Mlig455_011431 {REF} {Length: 4005} {TRANSSPLICED} {Pfam: PFU (PLAA family ubiquitin binding) [PF09070.13, score=131.6]; WD domain, G-beta repeat [PF00400.34, score=109.2]; PUL domain [PF08324.13, score=77.7]} {Human: ENSG00000137055, PLAA, phospholipase A2 activating protein, [RH, Score=449, Expect=1e-145]} {Mouse: ENSMUSG00000028577, Plaa, phospholipase A2, activating protein, [RH, Score=451, Expect=2e-146]} {Dmel: FBgn0024314, Plap, Phospholipase A2 activator protein, [RH, Score=368, Expect=8e-115]} {Celegans: WBGene00007333, ufd-3, Ubiquitin Fusion Degradation (Yeast UFD homolog), [RH, Score=214, Expect=4e-58]} {Smed: dd_Smed_v6_7764_0_1, dd_Smed_v6_7764_0_1, [RH, Score=244, Expect=1e-69]} {RNA1509_7328} {RNA1310_3644} {RNA815_2708}

Mlig455_061173 {REF} {Length: 4008} {TRANSSPLICED} {Pfam: PFU (PLAA family ubiquitin binding) [PF09070.13, score=131.6]; WD domain, G-beta repeat [PF00400.34, score=109.0]; PUL domain [PF08324.13, score=77.7]} {Human: ENSG00000137055, PLAA, phospholipase A2 activating protein, [RH, Score=448, Expect=3e-145]} {Mouse: ENSMUSG00000028577, Plaa, phospholipase A2, activating protein, [RH, Score=451, Expect=3e-146]} {Dmel: FBgn0024314, Plap, Phospholipase A2 activator protein, [RH, Score=368, Expect=6e-115]} {Celegans: WBGene00007333, ufd-3, Ubiquitin Fusion Degradation (Yeast UFD homolog), [RH, Score=213, Expect=5e-58]} {Smed: dd_Smed_v6_7764_0_1, dd_Smed_v6_7764_0_1, [RH, Score=244, Expect=8e-70]} {RNA1509_10785, RNA1509_31154, RNA1509_7328} {RNA1310_3644, RNA1509_10785, RNA1509_31154, RNA1509_7328} {RNA1509_10785, RNA1509_31154, RNA1509_7328, RNA815_2708}
41. MligTC455_16434 180 3.75 Mlig455_065893

Neo: Neoblast

Age: -

Region-enriched R4: 4.682/0.00000

0.965 - - - 0.965 - - Mlig455_065893 {REF} {Length: 1149} {RNA1310_54637} {RNA815_34864}
42. MligTC455_20102 307 6.39 Mlig455_022275

Neo: -

Age: -

EAPP 0.965 - - - 0.965 - - Mlig455_022275 {REF} {Length: 1458} {TRANSSPLICED} {Pfam: E2F-associated phosphoprotein [PF10238.11, score=139.4]} {Human: ENSG00000129518, EAPP, E2F associated phosphoprotein, [RH, Score=135, Expect=5e-39]} {Mouse: ENSMUSG00000054302, Eapp, E2F-associated phosphoprotein, [RH, Score=136, Expect=1e-39]} {Celegans: WBGene00018609, F48E8.2, [RH, Score=107, Expect=3e-27]} {Smed: dd_Smed_v6_3350_0_1, dd_Smed_v6_3350_0_1, [RH, Score=90.9, Expect=2e-23]} {RNA1509_35417, RNA1509_39727} {RNA1310_28043.1, RNA1509_35417} {RNA1509_35417, RNA815_23956}
43. MligTC455_40887 5552 115.66 Mlig455_060918

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.311

0.963 - - - 0.963 - - Mlig455_060918 {REF} {Length: 3401} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=76.2]} {Smed: dd_Smed_v6_8569_0_1, dd_Smed_v6_8569_0_1, [RH, Score=60.5, Expect=3e-09]} {RNA1509_3458, RNA1509_52549} {RNA1310_4975.1, RNA1509_3458} {RNA1509_3458, RNA815_1386.1}
44. MligTC455_41572 746 15.54 Mlig455_030760

Neo: Int S/G2/M

Age: Down-Up-Down

Region-enriched R5: 1.596/0.00078

0.955 - - 0.955 - - - Mlig455_030760 {REF} {Length: 2018} {TRANSSPLICED} {Pfam: DNA polymerase subunit Cdc27 [PF09507.12, score=38.5]} {RNA1509_21656, RNA1509_38904, RNA1509_41902} {RNA1310_13885, RNA1509_21656, RNA1509_38904, RNA1509_41902} {RNA1509_21656, RNA1509_38904, RNA1509_41902, RNA815_5435.1}
45. MligTC455_33033 68 1.42 Mlig455_023598

Neo: -

Age: Down-Up-Down

0.953 - - - - 0.953 - Mlig455_023598 {REF} {Length: 727} {NoTransDecoderORF} {RNA1509_44765} {RNA1310_83223} {RNA815_38104}
46. MligTC455_21951 112 2.34 Mlig455_013171

Neo: -

Age: logFC(26M/2M)=-0.620

ALPK1 0.952 - - - - 0.952 - Mlig455_013171 {REF} {Length: 3732} {Pfam: Alpha-kinase family [PF02816.20, score=112.1]; von Willebrand factor type A domain [PF13519.8, score=23.3]} {Human: ENSG00000073331, ALPK1, alpha kinase 1, [Score=58.2, Expect=8e-08]; ENSG00000284161, EEF2K, eukaryotic elongation factor 2 kinase, [Score=55.8, Expect=4e-07]; ENSG00000103319, EEF2K, eukaryotic elongation factor 2 kinase, [Score=55.8, Expect=4e-07]} {Mouse: ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=55.8, Expect=2e-07]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [Score=60.8, Expect=4e-09]} {Smed: dd_Smed_v6_2651_0_1, dd_Smed_v6_2651_0_1, [Score=60.1, Expect=6e-09]} {RNA1509_53723} {RNA1310_10777} {RNA815_22934}
47. MligTC455_26035 785 16.35 Mlig455_059000

Neo: -

Age: -

Region-enriched R5: 1.545/0.02057

GPT2 0.952 - - - - 0.952 - Mlig455_059000 {REF} {Length: 1739} {TRANSSPLICED} {Pfam: Aminotransferase class I and II [PF00155.23, score=127.2]} {Human: ENSG00000166123, GPT2, glutamic--pyruvic transaminase 2, [Score=471, Expect=2e-163]} {Mouse: ENSMUSG00000031700, Gpt2, glutamic pyruvate transaminase (alanine aminotransferase) 2, [Score=471, Expect=2e-163]; ENSMUSG00000022546, Gpt, glutamic pyruvic transaminase, soluble, [Score=464, Expect=3e-161]} {Dmel: FBgn0030478, CG1640, [Score=429, Expect=1e-146]} {Celegans: WBGene00016333, C32F10.8, [Score=431, Expect=3e-148]} {Smed: dd_Smed_v6_2988_0_1, dd_Smed_v6_2988_0_1, [Score=492, Expect=6e-173]} {RNA1509_20662, RNA1509_39983, RNA1509_58948} {RNA1310_12775, RNA1509_20662, RNA1509_39983, RNA1509_58948} {RNA1509_20662, RNA1509_39983, RNA1509_58948, RNA815_4235.2}
48. MligTC455_38442 716 14.92 Mlig455_036951, Mlig455_036986

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.481/0.00007

0.952 - - 0.952 - - -

Mlig455_036951 {REF} {Length: 1427} {TRANSSPLICED} {Pfam: Nuclear pore component [PF10168.11, score=23.3]} {RNA1509_16696, RNA1509_52776} {RNA1310_23813.1, RNA1509_16696, RNA1509_52776} {RNA1509_16696, RNA1509_52776, RNA815_33121}

Mlig455_036986 {REF} {Length: 1443} {TRANSSPLICED} {Pfam: Nuclear pore component [PF10168.11, score=25.2]} {RNA1509_52776} {RNA1310_23813.2} {RNA815_33121}
49. MligTC455_05594 72 1.49 Mlig455_065150

Neo: -

Age: -

Region-enriched R4: 4.074/0.00676

0.951 - - - 0.951 - - Mlig455_065150 {REF} {Length: 114} {NoTransDecoderORF} {RNA1509_53704} {RNA1310_56994.2} {RNA815_28634}
50. MligTC455_16703 414 8.62 Mlig455_043256, Mlig455_043281

Neo: -

Age: logFC(26M/2M)=0.464

Region-enriched R5: 2.416/0.00237

GOSR2 0.95 - - - 0.950 - -

Mlig455_043256 {REF} {Length: 998} {TRANSSPLICED} {Pfam: Snare region anchored in the vesicle membrane C-terminus [PF12352.10, score=54.6]; Sec20 [PF03908.15, score=21.1]} {Human: ENSG00000108433, GOSR2, golgi SNAP receptor complex member 2, [RH, Score=165, Expect=4e-51]} {Mouse: ENSMUSG00000020946, Gosr2, golgi SNAP receptor complex member 2, [RH, Score=176, Expect=2e-55]} {Dmel: FBgn0260856, Membrin, [RH, Score=137, Expect=2e-40]} {Celegans: WBGene00007128, memb-1, Golgi SNAP receptor complex member 2 homolog memb-1, [RH, Score=119, Expect=2e-33]} {Smed: dd_Smed_v6_7430_0_1, dd_Smed_v6_7430_0_1, [RH, Score=159, Expect=6e-49]} {RNA1509_13895} {RNA1310_2428.2} {RNA815_15259.1}

Mlig455_043281 {REF} {Length: 2773} {TRANSSPLICED} {Pfam: Snare region anchored in the vesicle membrane C-terminus [PF12352.10, score=54.6]; Sec20 [PF03908.15, score=21.0]} {Human: ENSG00000108433, GOSR2, golgi SNAP receptor complex member 2, [RH, Score=165, Expect=4e-51]} {Mouse: ENSMUSG00000020946, Gosr2, golgi SNAP receptor complex member 2, [RH, Score=176, Expect=1e-55]} {Dmel: FBgn0260856, Membrin, [RH, Score=137, Expect=3e-40]} {Celegans: WBGene00007128, memb-1, Golgi SNAP receptor complex member 2 homolog memb-1, [RH, Score=119, Expect=2e-33]} {Smed: dd_Smed_v6_7430_0_1, dd_Smed_v6_7430_0_1, [RH, Score=159, Expect=6e-49]} {RNA1509_13895} {RNA1310_2428.1} {RNA815_15259.1}

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