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Results for MligTC455_41393

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_41393 1315 27.39 Mlig455_056178

Neo: -

Age: logFC(26M/2M)=-0.489

 CDC14A Mlig455_056178 {REF} {Length: 4272} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=47.5]; Protein-tyrosine phosphatase [PF00102.29, score=22.8]; Inositol hexakisphosphate [PF14566.8, score=22.1]} {Human: ENSG00000079335, CDC14A, cell division cycle 14A, [Score=327, Expect=5e-106]; ENSG00000081377, CDC14B, cell division cycle 14B, [Score=313, Expect=6e-102]} {Mouse: ENSMUSG00000033502, Cdc14a, CDC14 cell division cycle 14A, [Score=325, Expect=2e-105]; ENSMUSG00000033102, Cdc14b, CDC14 cell division cycle 14B, [Score=310, Expect=3e-100]} {Dmel: FBgn0031952, cdc14, cell division cycle 14, [Score=275, Expect=8e-85]} {Celegans: WBGene00000383, cdc-14, Cell Division Cycle related, [Score=271, Expect=1e-83]} {Smed: dd_Smed_v6_7798_0_2, dd_Smed_v6_7798_0_2, [Score=334, Expect=7e-108]} {RNA1509_13598, RNA1509_1975, RNA1509_21888} {RNA1310_7304, RNA1509_13598, RNA1509_21888} {RNA1509_13598, RNA1509_21888, RNA815_1133}

Cumulative graph for MligTC455_41393

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.859 4.975 0.22473 0.86874
RegionR2 -0.124 4.975 0.72349 1.00000
RegionR3 -0.481 4.975 0.10966 0.57633
RegionR4 0.556 4.975 0.12303 0.35238
RegionR5 -0.399 4.975 0.16116 0.42297
RegionR6 -0.217 4.975 0.46832 1.00000
RegionR7 0.237 4.975 0.48740 1.00000
RegionR8 -0.432 4.975 0.34017 0.97393

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.766 4.975 0.10475 0.82638
RegenerationR2 -0.038 4.975 0.90303 1.00000
RegenerationR3 -0.135 4.975 0.70439 0.94950
RegenerationR4 -0.65 4.975 0.07761 0.44265
RegenerationR5 -0.412 4.975 0.23058 0.66454
RegenerationR6 -0.589 4.975 0.10652 0.40431
RegenerationBL -1.024 4.975 0.02148 0.15920
RegenerationTP -0.939 4.975 0.04073 0.33572


Genes with expression patterns similar to MligTC455_41393

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_41393 1315 27.39 Mlig455_056178

Neo: -

Age: logFC(26M/2M)=-0.489

 CDC14A 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_056178 {REF} {Length: 4272} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=47.5]; Protein-tyrosine phosphatase [PF00102.29, score=22.8]; Inositol hexakisphosphate [PF14566.8, score=22.1]} {Human: ENSG00000079335, CDC14A, cell division cycle 14A, [Score=327, Expect=5e-106]; ENSG00000081377, CDC14B, cell division cycle 14B, [Score=313, Expect=6e-102]} {Mouse: ENSMUSG00000033502, Cdc14a, CDC14 cell division cycle 14A, [Score=325, Expect=2e-105]; ENSMUSG00000033102, Cdc14b, CDC14 cell division cycle 14B, [Score=310, Expect=3e-100]} {Dmel: FBgn0031952, cdc14, cell division cycle 14, [Score=275, Expect=8e-85]} {Celegans: WBGene00000383, cdc-14, Cell Division Cycle related, [Score=271, Expect=1e-83]} {Smed: dd_Smed_v6_7798_0_2, dd_Smed_v6_7798_0_2, [Score=334, Expect=7e-108]} {RNA1509_13598, RNA1509_1975, RNA1509_21888} {RNA1310_7304, RNA1509_13598, RNA1509_21888} {RNA1509_13598, RNA1509_21888, RNA815_1133}
2. MligTC455_41392 1282 26.7 Mlig455_017725

Neo: -

Age: -

 CDC14A 5.892 0.990 0.973 0.995 0.996 0.939 0.999 Mlig455_017725 {REF} {Length: 4406} {Pfam: Dual specificity protein phosphatase, N-terminal half [PF14671.8, score=196.0]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=47.5]; Protein-tyrosine phosphatase [PF00102.29, score=22.3]; Inositol hexakisphosphate [PF14566.8, score=21.8]} {Human: ENSG00000079335, CDC14A, cell division cycle 14A, [RH, Score=554, Expect=0.0]} {Mouse: ENSMUSG00000033502, Cdc14a, CDC14 cell division cycle 14A, [RH, Score=546, Expect=0.0]} {Dmel: FBgn0031952, cdc14, cell division cycle 14, [RH, Score=451, Expect=4e-147]} {Celegans: WBGene00000383, cdc-14, Cell Division Cycle related, [RH, Score=355, Expect=3e-114]} {Smed: dd_Smed_v6_7798_0_1, dd_Smed_v6_7798_0_1, [RH, Score=556, Expect=0.0]} {RNA1509_1975} {RNA1310_7304, RNA1509_1975} {RNA1509_1975, RNA815_1133}
3. MligTC455_41394 1024 21.33 Mlig455_058724

Neo: -

Age: -

 4.608 0.946 0.927 0.774 0.974 - 0.987 Mlig455_058724 {REF} {Length: 1993} {NoTransDecoderORF} {RNA1509_21888} {RNA1310_17075.1} {RNA815_16401}
4. MligTC455_03538 380 7.91 Mlig455_005673

Neo: -

Age: logFC(26M/2M)=-0.275

Region-enriched R4: 2.162/0.04207

 TTLL5 1.898 - - - 0.947 - 0.951 Mlig455_005673 {REF} {Length: 5576} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=289.7]; YheC/D like ATP-grasp [PF14398.8, score=27.4]; Sugar-transfer associated ATP-grasp [PF14397.8, score=20.3]} {Human: ENSG00000119685, TTLL5, tubulin tyrosine ligase like 5, [RH, Score=624, Expect=0.0]} {Mouse: ENSMUSG00000012609, Ttll5, tubulin tyrosine ligase-like family, member 5, [RH, Score=627, Expect=0.0]} {Dmel: FBgn0051108, CG31108, [RH, Score=448, Expect=3e-141]} {Celegans: WBGene00008331, ttll-5, Tubulin Tyrosine Ligase Like, [RH, Score=331, Expect=5e-100]} {Smed: dd_Smed_v6_6390_0_1, dd_Smed_v6_6390_0_1, [RH, Score=747, Expect=0.0]} {RNA1509_10958} {RNA1310_2819} {RNA815_8454}
5. MligTC455_38106 572 11.92 Mlig455_059707

Neo: -

Age: logFC(26M/2M)=-0.405

 AK9 1.888 - - - 0.959 - 0.929 Mlig455_059707 {REF} {Length: 6057} {Pfam: Adenylate kinase [PF00406.24, score=145.8]; AAA domain [PF13207.8, score=69.8]; Domain of unknown function [PF12018.10, score=54.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=38.2]; AAA domain [PF13238.8, score=37.3]; YHS domain [PF04945.15, score=34.6]; AAA domain [PF13671.8, score=31.5]; AAA domain [PF13479.8, score=31.0]; AAA domain [PF13401.8, score=23.8]; Hydin Adenylate kinase-like domain [PF17213.5, score=21.7]; RNA helicase [PF00910.24, score=19.7]; AAA domain [PF13521.8, score=19.5]} {Human: ENSG00000155085, AK9, adenylate kinase 9, [RH, Score=1088, Expect=0.0]} {Mouse: ENSMUSG00000091415, Ak9, adenylate kinase 9, [RH, Score=1087, Expect=0.0]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=52.8, Expect=8e-07]} {Celegans: WBGene00009575, F40F8.1, UMP-CMP kinase 2, [Score=57.8, Expect=6e-09]} {Smed: dd_Smed_v6_9617_0_1, dd_Smed_v6_9617_0_1, [RH, Score=863, Expect=0.0]} {RNA1509_1039} {RNA1310_346} {RNA815_505}
6. MligTC455_46373 2937 61.2 Mlig455_026015

Neo: -

Age: logFC(26M/2M)=-0.228

 C7orf57 1.884 - - - 0.968 - 0.916 Mlig455_026015 {REF} {Length: 1844} {Pfam: Family of unknown function (DUF5524) [PF17662.3, score=74.1]} {Human: ENSG00000164746, C7orf57, chromosome 7 open reading frame 57, [RH, Score=69.7, Expect=8e-13]} {Mouse: ENSMUSG00000040978, Gm11992, predicted gene 11992, [RH, Score=70.5, Expect=2e-13]} {Smed: dd_Smed_v6_7900_0_1, dd_Smed_v6_7900_0_1, [RH, Score=95.9, Expect=2e-23]} {RNA1509_1352} {RNA1310_19460.1, RNA1509_1352} {RNA1509_1352, RNA815_7343}
7. MligTC455_40057 612 12.75 Mlig455_054931

Neo: -

Age: -

 FADS1 1.875 - - - 0.989 - 0.886 Mlig455_054931 {REF} {Length: 2003} {Pfam: Fatty acid desaturase [PF00487.26, score=114.0]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=63.0]} {Human: ENSG00000149485, FADS1, fatty acid desaturase 1, [Score=414, Expect=2e-141]; ENSG00000134824, FADS2, fatty acid desaturase 2, [Score=410, Expect=1e-140]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [Score=417, Expect=2e-143]; ENSMUSG00000010663, Fads1, fatty acid desaturase 1, [Score=402, Expect=1e-137]} {Dmel: FBgn0036575, CG5157, [Score=50.8, Expect=9e-08]} {Celegans: WBGene00001396, fat-4, Delta(5) fatty acid desaturase fat-4, [RH, Score=129, Expect=1e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [RH, Score=481, Expect=2e-169]} {RNA1509_36781} {RNA1310_14458, RNA1509_36781} {RNA1509_36781, RNA815_5784}
8. MligTC455_32991 254 5.29 Mlig455_019977

Neo: -

Age: -

 CFAP46 1.872 - - - 0.961 - 0.911 Mlig455_019977 {REF} {Length: 9379} {Human: ENSG00000171811, CFAP46, cilia and flagella associated protein 46, [RH, Score=1017, Expect=0.0]} {Mouse: ENSMUSG00000049571, Cfap46, cilia and flagella associated protein 46, [RH, Score=741, Expect=0.0]} {Smed: dd_Smed_v6_14103_0_1, dd_Smed_v6_14103_0_1, [RH, Score=827, Expect=0.0]} {RNA1509_5035} {RNA1310_152.1} {RNA815_852}
9. MligTC455_23584 574 11.95 Mlig455_050813

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.558

 CCDC33 1.836 - - - 0.951 - 0.885 Mlig455_050813 {REF} {Length: 3399} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=24.3]; C-terminal membrane-localisation domain of ion-channel, VCN1 [PF16799.7, score=19.4]} {Human: ENSG00000140481, CCDC33, coiled-coil domain containing 33, [RH, Score=94.4, Expect=4e-19]} {Mouse: ENSMUSG00000037716, Ccdc33, coiled-coil domain containing 33, [Score=145, Expect=4e-35]} {Smed: dd_Smed_v6_15844_0_1, dd_Smed_v6_15844_0_1, [RH, Score=191, Expect=6e-50]} {RNA1509_7141} {RNA1310_15581.1} {RNA815_780.1}
10. MligTC455_44157 2728 56.84 Mlig455_015483

Neo: -

Age: logFC(26M/2M)=-0.621

Region-enriched R4: 1.377/0.00397

 SPAG8 1.83 - - - 0.876 - 0.954 Mlig455_015483 {REF} {Length: 1025} {Human: ENSG00000137098, SPAG8, sperm associated antigen 8, [RH, Score=83.2, Expect=3e-18]} {Mouse: ENSMUSG00000066196, Spag8, sperm associated antigen 8, [RH, Score=90.9, Expect=4e-21]} {Smed: dd_Smed_v6_6123_0_1, dd_Smed_v6_6123_0_1, [RH, Score=131, Expect=1e-38]} {RNA1509_3548} {RNA1310_4106} {RNA815_16577}
11. MligTC455_27502 1437 29.93 Mlig455_011453

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.324

Region-specific R2: 2.256

Region-enriched R2: 1.844/0.00000
Region-enriched R3: 1.094/0.00220

 GSTO1 1.828 - - - 0.855 - 0.973 Mlig455_011453 {REF} {Length: 2033} {TRANSSPLICED} {Pfam: Glutathione S-transferase, N-terminal domain [PF13417.8, score=70.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=60.2]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=41.9]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=27.3]; Glutathione S-transferase, C-terminal domain [PF16865.7, score=19.4]} {Human: ENSG00000148834, GSTO1, glutathione S-transferase omega 1, [RH, Score=120, Expect=2e-32]} {Mouse: ENSMUSG00000025068, Gsto1, glutathione S-transferase omega 1, [Score=120, Expect=6e-33]} {Dmel: FBgn0086348, se, sepia, [RH, Score=135, Expect=1e-38]} {Celegans: WBGene00001792, gst-44, Glutathione S-Transferase, [RH, Score=117, Expect=8e-32]} {Smed: dd_Smed_v6_10355_0_1, dd_Smed_v6_10355_0_1, [Score=94.4, Expect=3e-23]} {RNA1509_47286, RNA1509_59404, RNA1509_6588} {RNA1310_13251, RNA1509_47286, RNA1509_59404, RNA1509_6588} {RNA1509_47286, RNA1509_59404, RNA1509_6588, RNA815_4551.1}
12. MligTC455_27503 1438 29.97 Mlig455_011534

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.218

Region-enriched R2: 1.795/0.00001
Region-enriched R3: 1.063/0.00278

 1.827 - - - 0.854 - 0.973 Mlig455_011534 {REF} {Length: 464} {RNA1509_23020} {RNA1310_13251} {RNA815_4551.1}
13. MligTC455_44156 2600 54.17 Mlig455_003573

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.373/0.00496

 SPAG8 1.816 - - - 0.854 - 0.962 Mlig455_003573 {REF} {Length: 1006} {Human: ENSG00000137098, SPAG8, sperm associated antigen 8, [RH, Score=81.6, Expect=8e-18]} {Mouse: ENSMUSG00000066196, Spag8, sperm associated antigen 8, [RH, Score=89.4, Expect=1e-20]} {Smed: dd_Smed_v6_6123_0_1, dd_Smed_v6_6123_0_1, [RH, Score=130, Expect=3e-38]} {RNA1509_11454, RNA1509_3548} {RNA1310_4106, RNA1509_11454} {RNA1509_11454, RNA815_16577}
14. MligTC455_20138 552 11.5 Mlig455_025065

Neo: -

Age: -

 C10orf67 1.815 - - - 0.970 - 0.845 Mlig455_025065 {REF} {Length: 2730} {Human: ENSG00000179133, C10orf67, chromosome 10 open reading frame 67, [Score=62.0, Expect=1e-09]} {Mouse: ENSMUSG00000026734, 4921504E06Rik, RIKEN cDNA 4921504E06 gene, [RH, Score=58.9, Expect=6e-09]} {RNA1509_39095} {RNA1310_11849} {RNA815_12876}
15. MligTC455_20139 549 11.45 Mlig455_025080

Neo: -

Age: logFC(26M/2M)=-0.355

 C10orf67 1.815 - - - 0.970 - 0.845 Mlig455_025080 {REF} {Length: 2190} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4709) [PF15821.7, score=70.4]} {Human: ENSG00000179133, C10orf67, chromosome 10 open reading frame 67, [RH, Score=96.7, Expect=2e-20]} {Mouse: ENSMUSG00000026734, 4921504E06Rik, RIKEN cDNA 4921504E06 gene, [RH, Score=59.7, Expect=7e-09]} {RNA1509_11167, RNA1509_39095} {RNA1310_11849, RNA1509_11167, RNA1509_39095} {RNA1509_11167, RNA1509_39095, RNA815_12876}
16. MligTC455_29437 897 18.69 Mlig455_049319, Mlig455_049403

Neo: -

Age: -

Region-enriched R8: 2.720/0.00033
Region-enriched R7: 1.911/0.02272

Regeneration-depleted TP: -2.721

 PKDREJ 1.813 - - - 0.954 - 0.859

Mlig455_049319 {REF} {Length: 10561} {Pfam: Polycystin cation channel [PF08016.14, score=289.6]; PLAT/LH2 domain [PF01477.25, score=81.7]; Ion transport protein [PF00520.33, score=61.2]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=294, Expect=1e-81]} {Mouse: ENSMUSG00000052496, Pkdrej, polycystin (PKD) family receptor for egg jelly, [Score=266, Expect=1e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=137, Expect=9e-33]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=156, Expect=3e-39]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=445, Expect=1e-132]} {RNA1509_2125} {RNA1310_81.1} {RNA815_193}

Mlig455_049403 {REF} {Length: 11572} {Pfam: Polycystin cation channel [PF08016.14, score=288.0]; PLAT/LH2 domain [PF01477.25, score=80.0]; Ion transport protein [PF00520.33, score=59.0]; PKD domain [PF18911.2, score=38.5]; PKD domain [PF00801.22, score=23.6]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=286, Expect=2e-76]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=271, Expect=7e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=142, Expect=2e-33]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=150, Expect=1e-36]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=486, Expect=6e-138]} {RNA1509_2125} {RNA1310_81.1} {RNA815_193}
17. MligTC455_21720 323 6.72 Mlig455_036807

Neo: -

Age: logFC(26M/2M)=-0.580

 TRPM3 1.81 - - - 0.965 - 0.845 Mlig455_036807 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=221.7]; SLOG in TRPM, prokaryote [PF18171.3, score=67.4]; Ion transport protein [PF00520.33, score=52.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=1e-156]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=518, Expect=3e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=5e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=604, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}
18. MligTC455_46254 1114 23.21 Mlig455_000448

Neo: -

Age: -

 CASC1 1.809 - - - 0.957 - 0.852 Mlig455_000448 {REF} {Length: 3104} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=168.4]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=29.2]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=320, Expect=4e-98]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=295, Expect=2e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=83.6, Expect=4e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1, RNA1509_1842} {RNA1509_1842, RNA815_2139}
19. MligTC455_24058 874 18.21 Mlig455_049588

Neo: -

Age: logFC(26M/2M)=0.283

 SYTL4 1.801 - - - 0.954 - 0.847 Mlig455_049588 {REF} {Length: 12642} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=68.1]; FYVE-type zinc finger [PF02318.18, score=53.4]; Protein of unknown function (DUF3139) [PF11337.10, score=20.6]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=100, Expect=3e-20]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=99.0, Expect=1e-19]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=100, Expect=3e-20]} {Dmel: FBgn0266756, btsz, bitesize, [Score=117, Expect=2e-25]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_4335_0_1, dd_Smed_v6_4335_0_1, [Score=84.7, Expect=5e-16]} {RNA1509_12528, RNA1509_2527} {RNA1310_245.3, RNA1509_12528} {RNA1509_12528, RNA815_559.1}
20. MligTC455_16915 607 12.65 Mlig455_012220

Neo: -

Age: -

 1.793 - - - 0.843 - 0.950 Mlig455_012220 {REF} {Length: 644} {TRANSSPLICED} {RNA1509_57998} {RNA1310_36675} {RNA815_24878}
21. MligTC455_43176 1391 28.98 Mlig455_031202

Neo: -

Age: -

 1.785 - - - 0.954 - 0.831 Mlig455_031202 {REF} {Length: 1602} {tRNA: Val(CAC),pseudo, score=27.7} {RNA1509_5906} {RNA1310_10573} {RNA815_3643}
22. MligTC455_43175 1395 29.07 Mlig455_031201

Neo: -

Age: logFC(26M/2M)=-0.710

 CAPN5 1.78 - - - 0.952 - 0.828 Mlig455_031201 {REF} {Length: 2222} {Pfam: Calpain family cysteine protease [PF00648.23, score=181.2]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=190, Expect=5e-52]; ENSG00000203697, CAPN8, calpain 8, [Score=182, Expect=6e-49]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=187, Expect=6e-51]; ENSMUSG00000038599, Capn8, calpain 8, [Score=186, Expect=3e-50]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=179, Expect=9e-49]} {Celegans: WBGene00000545, clp-4, CaLPain family, [Score=171, Expect=2e-45]} {Smed: dd_Smed_v6_1971_0_3, dd_Smed_v6_1971_0_3, [Score=166, Expect=1e-43]} {RNA1509_5906} {RNA1310_10573, RNA1509_5906} {RNA1509_5906, RNA815_3643}
23. MligTC455_38105 2374 49.46 Mlig455_015942

Neo: -

Age: logFC(26M/2M)=-0.373

 AK9 1.77 - - - 0.967 - 0.803 Mlig455_015942 {REF} {Length: 6588} {Pfam: Adenylate kinase [PF00406.24, score=148.4]; AAA domain [PF13207.8, score=69.1]; Domain of unknown function [PF12018.10, score=55.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=38.2]; AAA domain [PF13238.8, score=35.5]; YHS domain [PF04945.15, score=34.7]; AAA domain [PF13479.8, score=31.0]; AAA domain [PF13671.8, score=30.4]; AAA domain [PF13401.8, score=23.9]; Hydin Adenylate kinase-like domain [PF17213.5, score=21.5]; RNA helicase [PF00910.24, score=19.7]; AAA domain [PF13521.8, score=19.6]} {Human: ENSG00000155085, AK9, adenylate kinase 9, [RH, Score=1089, Expect=0.0]} {Mouse: ENSMUSG00000091415, Ak9, adenylate kinase 9, [RH, Score=1080, Expect=0.0]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=54.3, Expect=2e-07]} {Celegans: WBGene00009575, F40F8.1, UMP-CMP kinase 2, [Score=58.9, Expect=3e-09]} {Smed: dd_Smed_v6_9617_0_1, dd_Smed_v6_9617_0_1, [RH, Score=863, Expect=0.0]} {RNA1509_1039} {RNA1310_346} {RNA815_505}
24. MligTC455_23582 290 6.04 Mlig455_043258

Neo: -

Age: logFC(26M/2M)=-1.253

 CCDC33 1.765 - - - 0.953 - 0.812 Mlig455_043258 {REF} {Length: 3463} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=24.6]; C-terminal membrane-localisation domain of ion-channel, VCN1 [PF16799.7, score=19.4]} {Human: ENSG00000140481, CCDC33, coiled-coil domain containing 33, [RH, Score=94.7, Expect=4e-19]} {Mouse: ENSMUSG00000037716, Ccdc33, coiled-coil domain containing 33, [RH, Score=165, Expect=3e-41]} {Smed: dd_Smed_v6_15844_0_1, dd_Smed_v6_15844_0_1, [RH, Score=195, Expect=4e-51]} {RNA1509_7141} {RNA1310_3740, RNA1509_7141} {RNA1509_7141, RNA815_780.1}
25. MligTC455_48923 498 10.38 Mlig455_032490

Neo: -

Age: logFC(26M/2M)=-0.394

 IQCH 1.76 - - - 0.796 - 0.964 Mlig455_032490 {REF} {Length: 3574} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=26.0]} {Human: ENSG00000103599, IQCH, IQ motif containing H, [Score=594, Expect=0.0]} {Mouse: ENSMUSG00000037801, Iqch, IQ motif containing H, [Score=586, Expect=0.0]} {Smed: dd_Smed_v6_10544_0_1, dd_Smed_v6_10544_0_1, [Score=671, Expect=0.0]} {RNA1509_7338} {RNA1310_3995, RNA1509_7338} {RNA1509_7338, RNA815_1179}
26. MligTC455_34326 1040 21.67 Mlig455_031166

Neo: -

Age: Up-Down-Down

Region-enriched R4: 1.344/0.00349
Region-enriched R2: 1.196/0.04839

 DYNC2H1 1.74 - - - 0.789 - 0.951 Mlig455_031166 {REF} {Length: 14074} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=416.5]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=367.3]; ATP-binding dynein motor region [PF12781.9, score=251.1]; P-loop containing dynein motor region D4 [PF12780.9, score=174.1]; Dynein heavy chain, N-terminal region 1 [PF08385.14, score=151.3]; Dynein heavy chain C-terminal domain [PF18199.3, score=136.1]; Dynein heavy chain AAA lid domain [PF18198.3, score=127.6]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=127.1]; AAA domain (dynein-related subfamily) [PF07728.16, score=115.1]; P-loop containing dynein motor region [PF12775.9, score=85.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=46.7]; AAA ATPase domain [PF13191.8, score=42.4]; AAA domain [PF13401.8, score=34.5]; ABC transporter [PF00005.29, score=25.8]; AAA domain [PF13604.8, score=22.5]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=22.1]; AAA domain [PF13238.8, score=22.1]; AAA domain [PF13479.8, score=21.7]; P-loop containing region of AAA domain [PF13555.8, score=21.7]; RsgA GTPase [PF03193.18, score=21.6]; Midasin AAA lid domain [PF17867.3, score=20.9]; Growth-arrest specific micro-tubule binding [PF13851.8, score=20.8]; Domain of unknown function (DUF4164) [PF13747.8, score=19.6]; Rad17 P-loop domain [PF03215.17, score=19.1]; Type II/IV secretion system protein [PF00437.22, score=18.6]} {Human: ENSG00000187240, DYNC2H1, dynein cytoplasmic 2 heavy chain 1, [RH, Score=4970, Expect=0.0]} {Mouse: ENSMUSG00000047193, Dync2h1, dynein cytoplasmic 2 heavy chain 1, [RH, Score=4971, Expect=0.0]} {Dmel: FBgn0023096, btv, beethoven, [RH, Score=2033, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [RH, Score=3101, Expect=0.0]} {Smed: dd_Smed_v6_9136_0_1, dd_Smed_v6_9136_0_1, [RH, Score=5100, Expect=0.0]} {RNA1509_946} {RNA1310_60} {RNA815_256}
27. MligTC455_52005 543 11.31 Mlig455_004321

Neo: -

Age: -

Region-enriched R2: 2.171/0.00269

 SPAG6 1.705 - - - 0.731 - 0.974 Mlig455_004321 {REF} {Length: 2400} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=121.6]; HEAT repeats [PF13646.8, score=55.3]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=52.6]; HEAT repeat [PF02985.24, score=51.8]; HEAT-like repeat [PF13513.8, score=33.7]; C-terminal domain of two-partite extracellular sensor domain [PF17150.6, score=30.6]; DNA alkylation repair enzyme [PF08713.13, score=30.5]; Adaptin N terminal region [PF01602.22, score=30.0]; Proteasome non-ATPase 26S subunit [PF10508.11, score=21.9]; Rapamycin-insensitive companion of mTOR, N-term [PF14664.8, score=20.2]} {Human: ENSG00000077327, SPAG6, sperm associated antigen 6, [RH, Score=864, Expect=0.0]} {Mouse: ENSMUSG00000022783, Spag6l, sperm associated antigen 6-like, [RH, Score=880, Expect=0.0]} {Dmel: FBgn0027338, Kap-alpha3, karyopherin alpha3, [Score=67.0, Expect=2e-11]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [Score=71.6, Expect=4e-13]} {Smed: dd_Smed_v6_3991_0_1, dd_Smed_v6_3991_0_1, [RH, Score=895, Expect=0.0]} {RNA1509_4523} {RNA1310_15155.1} {RNA815_5882}
28. MligTC455_49256 1082 22.55 Mlig455_041198

Neo: -

Age: -

 MORN2 1.698 - - - 0.748 - 0.950 Mlig455_041198 {REF} {Length: 1758} {Pfam: MORN repeat [PF02493.22, score=64.6]} {Human: ENSG00000188010, MORN2, MORN repeat containing 2, [RH, Score=124, Expect=1e-36]} {Mouse: ENSMUSG00000045257, Morn2, MORN repeat containing 2, [RH, Score=127, Expect=8e-38]} {Dmel: FBgn0032478, CG5458, [Score=67.4, Expect=9e-14]} {Smed: dd_Smed_v6_6857_0_1, dd_Smed_v6_6857_0_1, [RH, Score=126, Expect=3e-38]} {RNA1509_23877, RNA1509_42709, RNA1509_7559} {RNA1310_23298, RNA1509_23877, RNA1509_7559} {RNA1509_23877, RNA1509_7559, RNA815_18336}
29. MligTC455_50361 844 17.58 Mlig455_000622

Neo: -

Age: Down-Up-Down

 DUSP22 1.688 0.732 - - 0.956 - - Mlig455_000622 {REF} {Length: 2298} {TRANSSPLICED} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=89.4]} {Human: ENSG00000112679, DUSP22, dual specificity phosphatase 22, [RH, Score=119, Expect=1e-32]} {Mouse: ENSMUSG00000069255, Dusp22, dual specificity phosphatase 22, [RH, Score=120, Expect=3e-33]} {Dmel: FBgn0036369, CG10089, [RH, Score=103, Expect=6e-25]} {Celegans: WBGene00006923, vhp-1, Tyrosine-protein phosphatase vhp-1, [Score=86.3, Expect=6e-19]} {Smed: dd_Smed_v6_4044_0_1, dd_Smed_v6_4044_0_1, [RH, Score=110, Expect=1e-28]} {RNA1509_21493, RNA1509_48380} {RNA1310_34562, RNA1509_21493, RNA1509_48380} {RNA1509_21493, RNA1509_48380, RNA815_16504}
30. MligTC455_48616 1121 23.36 Mlig455_045633

Neo: -

Age: -

 CCDC81 0.974 - - - - - 0.974 Mlig455_045633 {REF} {Length: 4045} {Pfam: CCDC81 eukaryotic HU domain 2 [PF18289.3, score=77.2]; CCDC81 eukaryotic HU domain 1 [PF14908.8, score=72.1]; Bacterial DNA-binding protein [PF00216.23, score=21.4]; HU domain fused to wHTH, Ig, or Glycine-rich motif [PF18291.3, score=18.8]} {Human: ENSG00000149201, CCDC81, coiled-coil domain containing 81, [RH, Score=242, Expect=6e-70]} {Mouse: ENSMUSG00000039391, Ccdc81, coiled-coil domain containing 81, [RH, Score=217, Expect=5e-61]} {Smed: dd_Smed_v6_6753_0_1, dd_Smed_v6_6753_0_1, [RH, Score=586, Expect=0.0]} {RNA1509_2273} {RNA1310_2378} {RNA815_610}
31. MligTC455_46850 265 5.52 Mlig455_005746

Neo: -

Age: -

Region-enriched R4: 2.659/0.01708

 0.968 - - - 0.968 - - Mlig455_005746 {REF} {Length: 3392} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=84.7, Expect=3e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=68.9, Expect=1e-11]} {RNA1509_46369, RNA1509_7522} {RNA1310_3662, RNA1509_46369, RNA1509_7522} {RNA1509_46369, RNA1509_7522, RNA815_5689}
32. MligTC455_48618 1040 21.66 Mlig455_045692

Neo: -

Age: logFC(26M/2M)=-0.486

 CCDC81 0.968 - - - - - 0.968 Mlig455_045692 {REF} {Length: 4129} {Pfam: CCDC81 eukaryotic HU domain 2 [PF18289.3, score=77.1]; CCDC81 eukaryotic HU domain 1 [PF14908.8, score=72.0]; Bacterial DNA-binding protein [PF00216.23, score=21.2]; HU domain fused to wHTH, Ig, or Glycine-rich motif [PF18291.3, score=18.9]} {Human: ENSG00000149201, CCDC81, coiled-coil domain containing 81, [RH, Score=242, Expect=9e-70]} {Mouse: ENSMUSG00000039391, Ccdc81, coiled-coil domain containing 81, [Score=218, Expect=5e-61]} {Smed: dd_Smed_v6_6753_0_1, dd_Smed_v6_6753_0_1, [RH, Score=588, Expect=0.0]} {RNA1509_2273} {RNA1310_2378} {RNA815_610}
33. MligTC455_23296 2396 49.92 Mlig455_031627, Mlig455_048206

Neo: -

Age: -

Region-enriched R4: 1.646/0.00418

 SLC25A36 0.967 - - - - - 0.967

Mlig455_031627 {REF} {Length: 2659} {Pfam: Mitochondrial carrier protein [PF00153.29, score=192.5]} {Human: ENSG00000114120, SLC25A36, solute carrier family 25 member 36, [Score=239, Expect=4e-77]} {Mouse: ENSMUSG00000032449, Slc25a36, solute carrier family 25, member 36, [Score=241, Expect=9e-78]} {Dmel: FBgn0031359, Rim2, Replication in mitochondria 2, [Score=237, Expect=6e-76]} {Celegans: WBGene00011662, T09F3.2, Carrier protein (C2), [Score=154, Expect=2e-43]} {Smed: dd_Smed_v6_8768_0_1, dd_Smed_v6_8768_0_1, [Score=240, Expect=2e-77]} {RNA1509_6549} {RNA1310_8160.1, RNA1509_6549} {RNA1509_6549, RNA815_7736.1}

Mlig455_048206 {REF} {Length: 3007} {Pfam: Mitochondrial carrier protein [PF00153.29, score=191.4]} {Human: ENSG00000114120, SLC25A36, solute carrier family 25 member 36, [Score=239, Expect=5e-77]} {Mouse: ENSMUSG00000032449, Slc25a36, solute carrier family 25, member 36, [Score=241, Expect=8e-78]} {Dmel: FBgn0031359, Rim2, Replication in mitochondria 2, [Score=237, Expect=1e-75]} {Celegans: WBGene00011662, T09F3.2, Carrier protein (C2), [Score=153, Expect=4e-43]} {Smed: dd_Smed_v6_8768_0_1, dd_Smed_v6_8768_0_1, [Score=240, Expect=2e-77]} {RNA1509_19691, RNA1509_6549} {RNA1310_8160.1, RNA1509_19691} {RNA1509_19691, RNA815_7736.1}
34. MligTC455_15064 658 13.7 Mlig455_022959

Neo: -

Age: -

 PRKAR1B 0.964 - - - - - 0.964 Mlig455_022959 {REF} {Length: 2850} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=131.0]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=32.8]} {Human: ENSG00000188191, PRKAR1B, protein kinase cAMP-dependent type I regulatory subunit beta, [Score=517, Expect=0.0]; ENSG00000108946, PRKAR1A, protein kinase cAMP-dependent type I regulatory subunit alpha, [Score=515, Expect=0.0]} {Mouse: ENSMUSG00000020612, Prkar1a, protein kinase, cAMP dependent regulatory, type I, alpha, [Score=523, Expect=0.0]; ENSMUSG00000025855, Prkar1b, protein kinase, cAMP dependent regulatory, type I beta, [Score=523, Expect=0.0]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [RH, Score=517, Expect=0.0]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=391, Expect=7e-135]} {Smed: dd_Smed_v6_11939_0_1, dd_Smed_v6_11939_0_1, [Score=420, Expect=4e-147]} {RNA1509_12094} {RNA1310_18531.1} {RNA815_7224}
35. MligTC455_22253 696 14.5 Mlig455_039989

Neo: -

Age: -

 H2AFY 0.959 - - - 0.959 - - Mlig455_039989 {REF} {Length: 2087} {TRANSSPLICED} {Pfam: Macro domain [PF01661.23, score=74.1]; C-terminus of histone H2A [PF16211.7, score=47.3]; Core histone H2A/H2B/H3/H4 [PF00125.26, score=33.0]} {Human: ENSG00000113648, H2AFY, H2A histone family member Y, [RH, Score=280, Expect=4e-91]} {Mouse: ENSMUSG00000015937, H2afy, H2A histone family, member Y, [RH, Score=280, Expect=3e-91]} {Dmel: FBgn0053853, His2A:CG33853, [Score=125, Expect=5e-35]} {Celegans: WBGene00001909, his-35, Histone H2A, [Score=118, Expect=2e-32]} {Smed: dd_Smed_v6_4487_0_1, dd_Smed_v6_4487_0_1, [RH, Score=241, Expect=2e-76]} {RNA1509_21701} {RNA1310_14229, RNA1509_21701} {RNA1509_21701, RNA815_13070}
36. MligTC455_46795 785 16.35 Mlig455_000535

Neo: -

Age: logFC(26M/2M)=-0.364

Region-enriched R2: 1.672/0.01916

 HTR1B 0.955 - - - - - 0.955 Mlig455_000535 {REF} {Length: 4573} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=255.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=53.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.4]; Family of unknown function (DUF5684) [PF18936.2, score=19.6]} {Human: ENSG00000135312, HTR1B, 5-hydroxytryptamine receptor 1B, [RH, Score=243, Expect=3e-75]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=251, Expect=3e-78]} {Dmel: FBgn0004573, 5-HT7, 5-hydroxytryptamine (serotonin) receptor 7, [RH, Score=276, Expect=2e-86]} {Celegans: WBGene00004780, ser-7, SERotonin/octopamine receptor family, [RH, Score=221, Expect=1e-66]} {Smed: dd_Smed_v6_5341_0_1, dd_Smed_v6_5341_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1310_3896.1, RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1509_11749, RNA1509_13593, RNA1509_37815, RNA815_3010}
37. MligTC455_49596 1668 34.74 Mlig455_063375

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R2: 1.067/0.02988

 ARMC4 0.954 - - - 0.954 - - Mlig455_063375 {REF} {Length: 3432} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=192.9]; HEAT repeats [PF13646.8, score=53.0]; Armadillo-like [PF04826.15, score=26.7]; V-ATPase subunit H [PF11698.10, score=26.4]; HEAT-like repeat [PF13513.8, score=26.1]; Kinesin-associated protein (KAP) [PF05804.14, score=24.7]; V-ATPase subunit H [PF03224.16, score=23.0]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=22.2]; HEAT repeat [PF02985.24, score=19.6]} {Human: ENSG00000169126, ARMC4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Mouse: ENSMUSG00000061802, Armc4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Dmel: FBgn0031905, gudu, [RH, Score=592, Expect=0.0]} {Smed: dd_Smed_v6_5065_0_1, dd_Smed_v6_5065_0_1, [RH, Score=932, Expect=0.0]} {RNA1509_1009, RNA1509_21601} {RNA1310_2954.1, RNA1509_1009, RNA1509_21601} {RNA1509_1009, RNA1509_21601, RNA815_1045}
38. MligTC455_52763 595 12.4 Mlig455_020629, Mlig455_048817

Neo: Irradiation

Age: Up-Down-Up

 DLC1 0.954 - - - 0.954 - -

Mlig455_020629 {REF} {Length: 4722} {Pfam: RhoGAP domain [PF00620.29, score=111.4]; START domain [PF01852.21, score=54.0]} {Human: ENSG00000164741, DLC1, DLC1 Rho GTPase activating protein, [RH, Score=375, Expect=1e-112]; ENSG00000285265, DLC1, DLC1 Rho GTPase activating protein, [RH, Score=375, Expect=1e-112]} {Mouse: ENSMUSG00000031523, Dlc1, deleted in liver cancer 1, [RH, Score=371, Expect=3e-108]} {Dmel: FBgn0285955, cv-c, crossveinless c, [RH, Score=341, Expect=1e-97]} {Celegans: WBGene00001559, gei-1, GEX Interacting protein, [RH, Score=228, Expect=9e-61]} {Smed: dd_Smed_v6_9530_0_1, dd_Smed_v6_9530_0_1, [RH, Score=344, Expect=1e-102]} {RNA1509_29640} {RNA1310_9000} {RNA815_6507}

Mlig455_048817 {REF} {Length: 3722} {Pfam: RhoGAP domain [PF00620.29, score=111.4]; START domain [PF01852.21, score=52.4]} {Human: ENSG00000285265, DLC1, DLC1 Rho GTPase activating protein, [RH, Score=380, Expect=3e-111]; ENSG00000164741, DLC1, DLC1 Rho GTPase activating protein, [RH, Score=380, Expect=3e-111]} {Mouse: ENSMUSG00000031523, Dlc1, deleted in liver cancer 1, [RH, Score=375, Expect=1e-109]} {Dmel: FBgn0285955, cv-c, crossveinless c, [RH, Score=344, Expect=1e-98]} {Celegans: WBGene00001559, gei-1, GEX Interacting protein, [RH, Score=231, Expect=7e-62]} {Smed: dd_Smed_v6_9530_0_1, dd_Smed_v6_9530_0_1, [RH, Score=343, Expect=2e-102]} {RNA1509_29640} {RNA1310_9000} {RNA815_6507}
39. MligTC455_43970 595 12.39 Mlig455_055475

Neo: -

Age: -

 CNBP 0.95 - - - - - 0.950 Mlig455_055475 {REF} {Length: 2082} {TRANSSPLICED} {Pfam: Zinc knuckle [PF00098.25, score=152.7]; Zinc knuckle [PF14392.8, score=40.9]; GAG-polyprotein viral zinc-finger [PF14787.8, score=31.5]; Zinc knuckle [PF13917.8, score=22.9]} {Human: ENSG00000169714, CNBP, CCHC-type zinc finger nucleic acid binding protein, [RH, Score=91.7, Expect=9e-23]} {Mouse: ENSMUSG00000030057, Cnbp, cellular nucleic acid binding protein, [RH, Score=91.7, Expect=6e-23]} {Dmel: FBgn0034802, CNBP, CCHC-type zinc finger nucleic acid binding protein, [RH, Score=80.5, Expect=7e-19]} {Celegans: WBGene00019537, K08D12.3, [Score=62.0, Expect=3e-12]} {Smed: dd_Smed_v6_947_0_1, dd_Smed_v6_947_0_1, [RH, Score=115, Expect=2e-32]} {RNA1509_36940, RNA1509_42112} {RNA1310_29194, RNA1509_36940, RNA1509_42112} {RNA1509_36940, RNA1509_42112, RNA815_13634}

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