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Results for MligTC455_41778

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_41778 3129 65.20 Mlig455_001612

Neo: Neoblast, stringent

Age: Down-Up-Up, logFC(26M/2M)=0.583

Region-enriched R5: 1.234/0.00079

 DKC1 Mlig455_001612 {REF} {Length: 1975} {TRANSSPLICED} {Pfam: tRNA pseudouridylate synthase B C-terminal domain [PF16198.7, score=71.2]; PUA domain [PF01472.22, score=70.9]; TruB family pseudouridylate synthase (N terminal domain) [PF01509.20, score=63.0]} {Human: ENSG00000130826, DKC1, dyskerin pseudouridine synthase 1, [Score=454, Expect=1e-157]} {Mouse: ENSMUSG00000031403, Dkc1, dyskeratosis congenita 1, dyskerin, [Score=451, Expect=2e-156]} {Dmel: FBgn0259937, Nop60B, Nucleolar protein at 60B, [Score=481, Expect=1e-168]} {Celegans: WBGene00010478, K01G5.5, Putative H/ACA ribonucleoprotein complex subunit 4, [Score=435, Expect=2e-151]} {Smed: dd_Smed_v6_4087_0_1, dd_Smed_v6_4087_0_1, [Score=374, Expect=5e-128]} {RNA1509_2479, RNA1509_40144} {RNA1310_14344.1, RNA1509_40144} {RNA1509_40144, RNA815_5205}

Cumulative graph for MligTC455_41778

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.043 6.227 0.17982 0.80829
RegionR2 -0.295 6.227 0.49058 0.87210
RegionR3 0.453 6.227 0.17885 0.70824
RegionR4 0.622 6.227 0.10082 0.30909
RegionR5 1.234 6.227 0.00004 0.00079
RegionR6 0.197 6.227 0.57146 1.00000
RegionR7 -0.225 6.227 0.57981 1.00000
RegionR8 -0.944 6.227 0.07746 0.53005

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.174 6.227 0.35851 1.00000
RegenerationR2 -0.277 6.227 0.50010 0.87170
RegenerationR3 0.562 6.227 0.17019 0.60515
RegenerationR4 0.901 6.227 0.03109 0.28459
RegenerationR5 0.454 6.227 0.25241 0.68550
RegenerationR6 1.325 6.227 0.00122 0.03855
RegenerationBL 1.196 6.227 0.00240 0.04066
RegenerationTP 1.067 6.227 0.01961 0.23989


Genes with expression patterns similar to MligTC455_41778

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_41778 3129 65.2 Mlig455_001612

Neo: Neoblast, stringent

Age: Down-Up-Up, logFC(26M/2M)=0.583

Region-enriched R5: 1.234/0.00079

 DKC1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_001612 {REF} {Length: 1975} {TRANSSPLICED} {Pfam: tRNA pseudouridylate synthase B C-terminal domain [PF16198.7, score=71.2]; PUA domain [PF01472.22, score=70.9]; TruB family pseudouridylate synthase (N terminal domain) [PF01509.20, score=63.0]} {Human: ENSG00000130826, DKC1, dyskerin pseudouridine synthase 1, [Score=454, Expect=1e-157]} {Mouse: ENSMUSG00000031403, Dkc1, dyskeratosis congenita 1, dyskerin, [Score=451, Expect=2e-156]} {Dmel: FBgn0259937, Nop60B, Nucleolar protein at 60B, [Score=481, Expect=1e-168]} {Celegans: WBGene00010478, K01G5.5, Putative H/ACA ribonucleoprotein complex subunit 4, [Score=435, Expect=2e-151]} {Smed: dd_Smed_v6_4087_0_1, dd_Smed_v6_4087_0_1, [Score=374, Expect=5e-128]} {RNA1509_2479, RNA1509_40144} {RNA1310_14344.1, RNA1509_40144} {RNA1509_40144, RNA815_5205}
2. MligTC455_41779 1714 35.71 Mlig455_047512

Neo: Neoblast, stringent

Age: Up-Down-Up

Region-enriched R5: 1.190/0.00563

 DKC1 3.505 - - 0.880 0.963 0.822 0.840 Mlig455_047512 {REF} {Length: 2101} {TRANSSPLICED} {Pfam: DKCLD (NUC011) domain [PF08068.14, score=108.8]; TruB family pseudouridylate synthase (N terminal domain) [PF01509.20, score=74.9]; tRNA pseudouridylate synthase B C-terminal domain [PF16198.7, score=60.8]; PUA domain [PF01472.22, score=56.9]} {Human: ENSG00000130826, DKC1, dyskerin pseudouridine synthase 1, [Score=542, Expect=0.0]} {Mouse: ENSMUSG00000031403, Dkc1, dyskeratosis congenita 1, dyskerin, [Score=543, Expect=0.0]} {Dmel: FBgn0259937, Nop60B, Nucleolar protein at 60B, [Score=571, Expect=0.0]} {Celegans: WBGene00010478, K01G5.5, Putative H/ACA ribonucleoprotein complex subunit 4, [Score=514, Expect=0.0]} {Smed: dd_Smed_v6_4087_0_1, dd_Smed_v6_4087_0_1, [Score=440, Expect=7e-153]} {RNA1509_2479} {RNA1310_14344.1} {RNA815_5205}
3. MligTC455_23027 1424 29.67 Mlig455_037516

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.237

Region-enriched R5: 1.343/0.00006
Region-enriched R4: 1.073/0.02114

 DHRS4 3.259 0.755 - 0.741 0.959 0.804 - Mlig455_037516 {REF} {Length: 4706} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=169.5]; short chain dehydrogenase [PF00106.27, score=111.5]; DDE superfamily endonuclease [PF03184.21, score=40.1]; OTU-like cysteine protease [PF02338.21, score=34.5]} {Human: ENSG00000284807, DHRS4, dehydrogenase/reductase 4, [Score=184, Expect=1e-51]; ENSG00000157326, DHRS4, dehydrogenase/reductase 4, [Score=184, Expect=1e-51]} {Mouse: ENSMUSG00000022210, Dhrs4, dehydrogenase/reductase (SDR family) member 4, [Score=179, Expect=4e-50]} {Dmel: FBgn0035588, CG10672, [Score=200, Expect=5e-57]} {Celegans: WBGene00000976, dhs-13, DeHydrogenases, Short chain, [Score=181, Expect=2e-51]} {Smed: dd_Smed_v6_6646_0_1, dd_Smed_v6_6646_0_1, [Score=190, Expect=2e-54]} {RNA1509_8082} {RNA1310_32758.3} {RNA815_14440.1}
4. MligTC455_19147 1473 30.69 Mlig455_056113

Neo: Neoblast

Age: -

Regeneration-enriched BL: 1.795
Regeneration-enriched R6: 1.665

 TOMM22 2.555 - 0.852 - 0.950 - 0.753 Mlig455_056113 {REF} {Length: 1665} {TRANSSPLICED} {Pfam: Mitochondrial import receptor subunit Tom22 [PF04281.15, score=46.5]} {Human: ENSG00000100216, TOMM22, translocase of outer mitochondrial membrane 22, [RH, Score=50.8, Expect=2e-08]} {Mouse: ENSMUSG00000022427, Tomm22, translocase of outer mitochondrial membrane 22, [RH, Score=48.5, Expect=2e-07]} {Dmel: FBgn0035473, mge, maggie, [RH, Score=73.9, Expect=2e-17]} {Celegans: WBGene00021133, tomm-22, Mitochondrial import receptor subunit TOM22 homolog, [RH, Score=76.6, Expect=5e-19]} {Smed: dd_Smed_v6_2455_0_1, dd_Smed_v6_2455_0_1, [RH, Score=44.3, Expect=2e-06]} {RNA1509_10010, RNA1509_7031} {RNA1310_43451, RNA1509_10010, RNA1509_7031} {RNA1509_10010, RNA1509_7031, RNA815_36165}
5. MligTC455_21445 13458 280.38 Mlig455_038347

Neo: Neoblast

Age: -

 RAN 1.811 - - - 0.965 0.846 - Mlig455_038347 {REF} {Length: 1519} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=172.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=110.3]; ADP-ribosylation factor family [PF00025.23, score=44.0]; 50S ribosome-binding GTPase [PF01926.25, score=23.9]; RNA helicase [PF00910.24, score=22.7]; RsgA GTPase [PF03193.18, score=19.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.2]; G-protein alpha subunit [PF00503.22, score=18.2]} {Human: ENSG00000132341, RAN, RAN, member RAS oncogene family, [RH, Score=381, Expect=5e-136]} {Mouse: ENSMUSG00000029430, Ran, RAN, member RAS oncogene family, [RH, Score=381, Expect=4e-136]; ENSMUSG00000028287, 1700009N14Rik, RIKEN cDNA 1700009N14 gene, [RH, Score=373, Expect=4e-133]; ENSMUSG00000083649, Rasl2-9, RAS-like, family 2, locus 9, [RH, Score=362, Expect=1e-128]} {Dmel: FBgn0020255, Ran, [RH, Score=366, Expect=3e-130]} {Celegans: WBGene00004302, ran-1, GTP-binding nuclear protein ran-1, [RH, Score=369, Expect=2e-131]} {Smed: dd_Smed_v6_330_0_1, dd_Smed_v6_330_0_1, [RH, Score=380, Expect=4e-136]} {RNA1509_15492, RNA1509_845} {RNA1310_21472.1, RNA1509_15492, RNA1509_845} {RNA1509_15492, RNA1509_845, RNA815_8699}
6. MligTC455_37896 4590 95.62 Mlig455_048970

Neo: -

Age: logFC(26M/2M)=0.339

Region-enriched R4: 1.540/0.00001

 1.701 - - - 0.956 - 0.745 Mlig455_048970 {REF} {Length: 1062} {Smed: dd_Smed_v6_951_0_1, dd_Smed_v6_951_0_1, [RH, Score=59.7, Expect=5e-13]} {RNA1509_1589} {RNA1310_12812.1} {RNA815_14113}
7. MligTC455_22405 816 17.01 Mlig455_019226

Neo: -

Age: -

Region-enriched R4: 1.356/0.00404
Region-enriched R5: 1.261/0.00013

 UPRT 1.692 - - - 0.958 - 0.734 Mlig455_019226 {REF} {Length: 3530} {TRANSSPLICED} {Pfam: Uracil phosphoribosyltransferase [PF14681.8, score=148.6]} {Human: ENSG00000094841, UPRT, uracil phosphoribosyltransferase homolog, [RH, Score=233, Expect=2e-75]} {Mouse: ENSMUSG00000073016, Uprt, uracil phosphoribosyltransferase, [RH, Score=238, Expect=2e-77]} {Dmel: FBgn0035639, kri, krishah, [RH, Score=228, Expect=2e-74]} {Celegans: WBGene00008131, C47B2.2, [RH, Score=197, Expect=1e-62]} {Smed: dd_Smed_v6_6546_0_1, dd_Smed_v6_6546_0_1, [RH, Score=226, Expect=2e-74]} {RNA1509_14966} {RNA1310_21510.1} {RNA815_14342}
8. MligTC455_11503 149 3.1 Mlig455_003254, Mlig455_003341

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.865

 UHRF1 0.973 - - - - 0.973 -

Mlig455_003254 {REF} {Length: 2536} {TRANSSPLICED} {Pfam: SAD/SRA domain [PF02182.19, score=169.0]} {Human: ENSG00000276043, UHRF1, ubiquitin like with PHD and ring finger domains 1, [Score=152, Expect=2e-38]} {Mouse: ENSMUSG00000001228, Uhrf1, ubiquitin-like, containing PHD and RING finger domains, 1, [Score=154, Expect=3e-39]} {RNA1509_25446} {RNA1310_8743} {RNA815_6882}

Mlig455_003341 {REF} {Length: 1683} {TRANSSPLICED} {Pfam: SAD/SRA domain [PF02182.19, score=169.2]} {Human: ENSG00000276043, UHRF1, ubiquitin like with PHD and ring finger domains 1, [Score=152, Expect=1e-38]} {Mouse: ENSMUSG00000001228, Uhrf1, ubiquitin-like, containing PHD and RING finger domains, 1, [Score=155, Expect=1e-39]} {RNA1509_25446} {RNA1310_8743} {RNA815_6882}
9. MligTC455_44414 594 12.38 Mlig455_054465

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.220/0.00367
Region-enriched R4: 1.175/0.03476

Regeneration-upregulated R6: 1.867

Regeneration-enriched R6: 1.867

 TOP2A 0.965 - - - 0.965 - - Mlig455_054465 {REF} {Length: 4574} {Pfam: DNA gyrase/topoisomerase IV, subunit A [PF00521.22, score=407.9]; C-terminal associated domain of TOPRIM [PF16898.7, score=149.7]; DNA gyrase B [PF00204.27, score=73.7]; Toprim domain [PF01751.24, score=33.3]} {Human: ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=1059, Expect=0.0]; ENSG00000077097, TOP2B, DNA topoisomerase II beta, [Score=1051, Expect=0.0]} {Mouse: ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=1072, Expect=0.0]; ENSMUSG00000017485, Top2b, topoisomerase (DNA) II beta, [Score=1047, Expect=0.0]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=981, Expect=0.0]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=969, Expect=0.0]} {Smed: dd_Smed_v6_1626_0_2, dd_Smed_v6_1626_0_2, [Score=983, Expect=0.0]} {RNA1509_2428} {RNA1310_1442} {RNA815_409}
10. MligTC455_48649 2564 53.41 Mlig455_042106

Neo: Neoblast, stringent

Age: Down-Up-Up

Region-enriched R5: 1.430/0.00000

 CKS2 0.958 - - - 0.958 - - Mlig455_042106 {REF} {Length: 951} {Pfam: Cyclin-dependent kinase regulatory subunit [PF01111.21, score=105.4]} {Human: ENSG00000123975, CKS2, CDC28 protein kinase regulatory subunit 2, [RH, Score=99.0, Expect=2e-28]} {Mouse: ENSMUSG00000062248, Cks2, CDC28 protein kinase regulatory subunit 2, [RH, Score=99.4, Expect=1e-28]} {Dmel: FBgn0037613, Cks85A, Cyclin-dependent kinase subunit 85A, [RH, Score=95.1, Expect=5e-27]} {Celegans: WBGene00001051, cks-1, Cyclin-dependent kinases regulatory subunit, [RH, Score=100, Expect=4e-29]} {Smed: dd_Smed_v6_6668_0_1, dd_Smed_v6_6668_0_1, [Score=107, Expect=6e-32]} {RNA1509_14224, RNA1509_28981, RNA1509_56838, RNA1509_9629} {RNA1310_23784, RNA1509_14224, RNA1509_28981, RNA1509_56838, RNA1509_9629} {RNA1509_14224, RNA1509_28981, RNA1509_56838, RNA1509_9629, RNA815_10824}
11. MligTC455_52400 1082 22.55 Mlig455_011305, Mlig455_022486, Mlig455_038582, Mlig455_056863, Mlig455_057049, Mlig455_057669, Mlig455_061128

Neo: -

Age: Down-Up-Down

 0.952 0.952 - - - - -

Mlig455_011305 {REF} {Length: 652} {RNA1509_14690} {RNA1310_66185} {RNA815_31052}

Mlig455_022486 {REF} {Length: 1105} {RNA1509_17097} {RNA1310_27479.2} {RNA815_19373}

Mlig455_038582 {REF} {Length: 935} {RNA1509_17097} {RNA1310_27479.2} {RNA815_19373}

Mlig455_056863 {REF} {Length: 1065} {RNA1509_17097} {RNA1310_27479.2} {RNA815_19373}

Mlig455_057049 {REF} {Length: 1487} {RNA1509_17097} {RNA1310_27479.2} {RNA815_19373}

Mlig455_057669 {REF} {Length: 326} {NoTransDecoderORF} {RNA1509_17097} {RNA1310_27479.2} {RNA815_19373}

Mlig455_061128 {REF} {Length: 2461} {Pfam: Gp5 C-terminal repeat (3 copies) [PF06715.14, score=22.0]} {RNA1509_17097, RNA1509_2910} {RNA1310_27479.2, RNA1509_2910} {RNA1509_2910, RNA815_19373}
12. MligTC455_42243 1197 24.93 Mlig455_002520

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.357

Region-specific R5: 3.136

Region-enriched R5: 2.806/0.00000
Region-enriched R6: 1.322/0.04695

 0.95 - - - 0.950 - - Mlig455_002520 {REF} {Length: 1175} {TRANSSPLICED} {RNA1509_56655} {RNA1310_26126, RNA1509_56655} {RNA1509_56655, RNA815_12984}

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