Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_42191 | 379 | 7.90 | Mlig455_012126, Mlig455_029001 | Neo: - Age: Down-Up-Up |
Mlig455_012126 {REF} {Length: 1565} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=53.1, Expect=4e-09]} {RNA1310_28170} {RNA815_25748} Mlig455_029001 {REF} {Length: 1721} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=52.8, Expect=6e-09]} {RNA1509_52997} {RNA1310_28170} {RNA815_25748} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -6.816 | 3.168 | 0.06037 | 0.56353 | |
RegionR2 | 0.29 | 3.168 | 0.73258 | 1.00000 | |
RegionR3 | 0.064 | 3.168 | 0.82999 | 1.00000 | |
RegionR4 | 1.23 | 3.168 | 0.21782 | 0.50543 | |
RegionR5 | 0.095 | 3.168 | 0.81872 | 1.00000 | |
RegionR6 | 0.753 | 3.168 | 0.43153 | 0.99509 | |
RegionR7 | 2.38 | 3.168 | 0.00253 | 0.06773 | |
RegionR8 | 2.004 | 3.168 | 0.04850 | 0.43213 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.486 | 3.168 | 1.00000 | 1.00000 | |
RegenerationR2 | -0.224 | 3.168 | 0.73730 | 0.96879 | |
RegenerationR3 | -0.61 | 3.168 | 0.40423 | 0.80549 | |
RegenerationR4 | -1.183 | 3.168 | 0.10939 | 0.50834 | |
RegenerationR5 | -0.313 | 3.168 | 0.66608 | 0.93879 | |
RegenerationR6 | -0.402 | 3.168 | 0.56562 | 0.84886 | |
RegenerationBL | -0.833 | 3.168 | 0.22943 | 0.57996 | |
RegenerationTP | -0.846 | 3.168 | 0.25699 | 0.70471 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_42191 | 379 | 7.9 | Mlig455_012126, Mlig455_029001 | Neo: - Age: Down-Up-Up |
6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_012126 {REF} {Length: 1565} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=53.1, Expect=4e-09]} {RNA1310_28170} {RNA815_25748} Mlig455_029001 {REF} {Length: 1721} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=52.8, Expect=6e-09]} {RNA1509_52997} {RNA1310_28170} {RNA815_25748} |
|
2. | MligTC455_42720 | 246 | 5.13 | Mlig455_024695, Mlig455_024719 | Neo: - |
CHRNA3 | 1.777 | - | - | - | - | 0.811 | 0.966 | Mlig455_024695 {REF} {Length: 2853} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=153.6]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=71.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=188, Expect=7e-54]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=186, Expect=3e-53]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=187, Expect=8e-54]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=187, Expect=1e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=185, Expect=2e-53]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=179, Expect=9e-51]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=194, Expect=4e-56]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=179, Expect=2e-50]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=314, Expect=2e-103]} {RNA1509_30530} {RNA1310_16567} {RNA815_2979.1} Mlig455_024719 {REF} {Length: 3783} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=153.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.8]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=192, Expect=8e-55]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=190, Expect=3e-54]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=193, Expect=2e-55]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=192, Expect=6e-55]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=187, Expect=1e-53]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=187, Expect=2e-53]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=196, Expect=6e-56]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=179, Expect=5e-50]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=316, Expect=1e-103]} {RNA1509_30530} {RNA1310_16567, RNA1509_30530} {RNA1509_30530, RNA815_2979.1} |
3. | MligTC455_24742 | 826 | 17.2 | Mlig455_054549 | Neo: - Age: Up-Down-Up, logFC(26M/2M)=0.679 Region-enriched R4: 1.479/0.04705 |
CDO1 | 1.738 | 0.780 | 0.958 | - | - | - | - | Mlig455_054549 {REF} {Length: 1570} {Pfam: Cysteine dioxygenase type I [PF05995.14, score=44.1]} {Human: ENSG00000129596, CDO1, cysteine dioxygenase type 1, [Score=75.5, Expect=7e-16]} {Mouse: ENSMUSG00000033022, Cdo1, cysteine dioxygenase 1, cytosolic, [Score=74.7, Expect=6e-16]} {Dmel: FBgn0034364, CG5493, [Score=82.4, Expect=2e-18]} {Celegans: WBGene00018986, cdo-1, Cysteine dioxygenase 1, [Score=79.3, Expect=8e-18]} {Smed: dd_Smed_v6_3640_0_1, dd_Smed_v6_3640_0_1, [Score=68.6, Expect=8e-14]} {RNA1509_3112} {RNA1310_25521} {RNA815_10217} |
4. | MligTC455_50257 | 215 | 4.48 | Mlig455_011262 | Neo: - Age: - |
1.679 | - | - | - | 0.728 | - | 0.951 | Mlig455_011262 {REF} {Length: 864} {NoTransDecoderORF} {RNA1310_36714.1} {RNA815_32855.1} | |
5. | MligTC455_38674 | 804 | 16.74 | Mlig455_057215, Mlig455_066650 | Neo: - Age: - |
MAP3K7 | 0.965 | - | - | 0.965 | - | - | - | Mlig455_057215 {REF} {Length: 2896} {Pfam: Protein kinase domain [PF00069.27, score=158.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=152.2]; Fungal protein kinase [PF17667.3, score=25.3]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=23.2]; MraW methylase family [PF01795.21, score=22.4]} {Human: ENSG00000135341, MAP3K7, mitogen-activated protein kinase kinase kinase 7, [Score=154, Expect=4e-40]} {Mouse: ENSMUSG00000028284, Map3k7, mitogen-activated protein kinase kinase kinase 7, [Score=154, Expect=3e-40]} {Dmel: FBgn0026323, Tak1, TGF-beta activated kinase 1, [Score=115, Expect=1e-26]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [Score=103, Expect=6e-23]} {Smed: dd_Smed_v6_953_0_1, dd_Smed_v6_953_0_1, [Score=128, Expect=1e-31]} {RNA1509_6833} {RNA1310_9609} {RNA815_3249.1} Mlig455_066650 {REF} {Length: 3026} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.3]; Protein kinase domain [PF00069.27, score=113.4]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=24.5]} {Human: ENSG00000135341, MAP3K7, mitogen-activated protein kinase kinase kinase 7, [Score=108, Expect=1e-26]} {Mouse: ENSMUSG00000028284, Map3k7, mitogen-activated protein kinase kinase kinase 7, [Score=108, Expect=7e-27]} {Dmel: FBgn0000723, FER, FER tyrosine kinase, [Score=89.7, Expect=1e-20]} {Celegans: WBGene00003931, pat-4, Integrin-linked protein kinase homolog pat-4, [Score=82.8, Expect=4e-18]} {Smed: dd_Smed_v6_953_0_1, dd_Smed_v6_953_0_1, [Score=85.1, Expect=5e-19]} {RNA1509_47567} {RNA1310_11206} {RNA815_3249.1} |
6. | MligTC455_36826 | 28 | 0.58 | Mlig455_013198 | Neo: - Age: - Region-enriched R2: 5.359/0.01396 |
HSPB6 | 0.963 | - | 0.963 | - | - | - | - | Mlig455_013198 {REF} {Length: 2372} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=56.3]} {Human: ENSG00000004776, HSPB6, heat shock protein family B (small) member 6, [RH, Score=55.5, Expect=8e-09]} {Mouse: ENSMUSG00000036854, Hspb6, heat shock protein, alpha-crystallin-related, B6, [RH, Score=58.5, Expect=7e-10]} {Dmel: FBgn0011296, l(2)efl, lethal (2) essential for life, [Score=57.8, Expect=1e-09]} {Smed: dd_Smed_v6_15128_0_1, dd_Smed_v6_15128_0_1, [RH, Score=81.3, Expect=3e-17]} {RNA1310_41920} {RNA815_42079} |
7. | MligTC455_36882 | 118 | 2.45 | Mlig455_040028 | Neo: Int S/G2/M Age: - |
0.963 | - | - | - | - | - | 0.963 | Mlig455_040028 {REF} {Length: 3355} {RNA1509_39805} {RNA1310_24031, RNA1509_39805} {RNA1509_39805, RNA815_10951.1} | |
8. | MligTC455_53096 | 1330 | 27.71 | Mlig455_068899 | Neo: - Age: Down-Up-Down |
SEC14L2 | 0.963 | - | - | - | - | 0.963 | - | Mlig455_068899 {REF} {Length: 1803} {Pfam: CRAL/TRIO domain [PF00650.22, score=99.2]; Golgi-dynamics membrane-trafficking [PF13897.8, score=36.4]} {Human: ENSG00000100003, SEC14L2, SEC14 like lipid binding 2, [RH, Score=278, Expect=1e-89]; ENSG00000133488, SEC14L4, SEC14 like lipid binding 4, [RH, Score=269, Expect=4e-86]; ENSG00000100012, SEC14L3, SEC14 like lipid binding 3, [RH, Score=266, Expect=6e-85]} {Mouse: ENSMUSG00000003585, Sec14l2, SEC14-like lipid binding 2, [RH, Score=277, Expect=2e-89]} {Dmel: FBgn0035146, CG13893, [RH, Score=190, Expect=5e-56]} {Celegans: WBGene00019268, H41C03.1, [RH, Score=119, Expect=1e-29]} {Smed: dd_Smed_v6_11513_1_1, dd_Smed_v6_11513_1_1, [RH, Score=282, Expect=3e-92]} {RNA1509_13482} {RNA1310_16456, RNA1509_13482} {RNA1509_13482, RNA815_6612} |
9. | MligTC455_45712 | 91 | 1.89 | Mlig455_050761, Mlig455_050791 | Neo: - Age: - |
0.959 | - | 0.959 | - | - | - | - | Mlig455_050761 {REF} {Length: 2816} {RNA1509_10628} {RNA1310_39724.1} {RNA815_34935} Mlig455_050791 {REF} {Length: 2817} {RNA1509_10628} {RNA1310_39724.1} {RNA815_34935} |
|
10. | MligTC455_49833 | 125 | 2.61 | Mlig455_070010 | Neo: - Age: - |
0.958 | - | - | - | - | - | 0.958 | Mlig455_070010 {REF} {Length: 4603} {RNA1509_22628} {RNA1310_1605.1} {RNA815_22526} | |
11. | MligTC455_53628 | 724 | 15.09 | Mlig455_060297 | Neo: - Age: Down-Up-Up |
ADGRA3 | 0.957 | - | 0.957 | - | - | - | - | Mlig455_060297 {REF} {Length: 2032} {Pfam: Leucine rich repeat [PF13855.8, score=61.4]} {Human: ENSG00000152990, ADGRA3, adhesion G protein-coupled receptor A3, [Score=49.3, Expect=1e-05]; ENSG00000187122, SLIT1, slit guidance ligand 1, [Score=49.3, Expect=1e-05]} {Mouse: ENSMUSG00000025020, Slit1, slit guidance ligand 1, [Score=50.8, Expect=2e-06]; ENSMUSG00000029090, Adgra3, adhesion G protein-coupled receptor A3, [Score=48.9, Expect=1e-05]; ENSMUSG00000044505, Lingo4, leucine rich repeat and Ig domain containing 4, [Score=48.5, Expect=1e-05]} {Dmel: FBgn0264089, sli, slit, [Score=53.5, Expect=2e-07]} {RNA1509_49012} {RNA1310_15910.1} {RNA815_6013} |
12. | MligTC455_07100 | 97 | 2.02 | Mlig455_003124, Mlig455_014179 | Neo: - Age: - |
POU4F1 | 0.953 | - | 0.953 | - | - | - | - | Mlig455_003124 {REF} {Length: 2773} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=109.3]; Homeodomain [PF00046.31, score=67.1]; Helix-turn-helix domain [PF13560.8, score=22.0]} {Human: ENSG00000152192, POU4F1, POU class 4 homeobox 1, [RH, Score=271, Expect=6e-87]; ENSG00000151615, POU4F2, POU class 4 homeobox 2, [RH, Score=269, Expect=4e-86]; ENSG00000091010, POU4F3, POU class 4 homeobox 3, [RH, Score=267, Expect=2e-86]} {Mouse: ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [RH, Score=271, Expect=6e-87]; ENSMUSG00000031688, Pou4f2, POU domain, class 4, transcription factor 2, [RH, Score=268, Expect=3e-86]; ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [RH, Score=267, Expect=2e-86]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [RH, Score=264, Expect=4e-85]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [RH, Score=236, Expect=2e-74]} {Smed: dd_Smed_v6_15555_0_1, dd_Smed_v6_15555_0_1, [RH, Score=305, Expect=7e-101]} {RNA1509_57422} {RNA1310_8139.2} {RNA815_32659} Mlig455_014179 {REF} {Length: 532} {NoTransDecoderORF} {RNA1310_72815} {RNA815_37705} |
13. | MligTC455_40233 | 550 | 11.46 | Mlig455_010288, Mlig455_010326 | Neo: - Age: - Region-enriched R8: 2.427/0.01141 |
UNC5A | 0.953 | - | 0.953 | - | - | - | - | Mlig455_010288 {REF} {Length: 5227} {Pfam: ZU5 domain [PF00791.22, score=95.5]; UPA domain [PF17217.5, score=68.9]; Death domain [PF00531.24, score=52.5]; Immunoglobulin domain [PF13927.8, score=23.3]; Immunoglobulin domain [PF00047.27, score=19.7]} {Human: ENSG00000113763, UNC5A, unc-5 netrin receptor A, [RH, Score=213, Expect=1e-56]} {Mouse: ENSMUSG00000025876, Unc5a, unc-5 netrin receptor A, [RH, Score=211, Expect=3e-56]} {Dmel: FBgn0034013, unc-5, [Score=95.9, Expect=1e-19]} {Celegans: WBGene00006745, unc-5, Netrin receptor unc-5, [Score=174, Expect=2e-44]} {Smed: dd_Smed_v6_10730_0_1, dd_Smed_v6_10730_0_1, [Score=306, Expect=1e-88]} {RNA1509_46036} {RNA1310_39257} {RNA815_1054.1} Mlig455_010326 {REF} {Length: 5544} {Pfam: ZU5 domain [PF00791.22, score=96.1]; UPA domain [PF17217.5, score=70.1]; Death domain [PF00531.24, score=52.9]} {Human: ENSG00000113763, UNC5A, unc-5 netrin receptor A, [RH, Score=214, Expect=2e-58]} {Mouse: ENSMUSG00000025876, Unc5a, unc-5 netrin receptor A, [RH, Score=211, Expect=1e-57]} {Dmel: FBgn0034013, unc-5, [Score=93.6, Expect=3e-19]} {Celegans: WBGene00006745, unc-5, Netrin receptor unc-5, [RH, Score=133, Expect=4e-32]} {Smed: dd_Smed_v6_10730_0_1, dd_Smed_v6_10730_0_1, [Score=278, Expect=3e-81]} {RNA1509_46036} {RNA1310_8280.2} {RNA815_1054.1} |
14. | MligTC455_51074 | 585 | 12.2 | Mlig455_054379, Mlig455_054401 | Neo: - Age: - |
0.953 | - | 0.953 | - | - | - | - | Mlig455_054379 {REF} {Length: 2291} {RNA1310_46059} {RNA815_34780} Mlig455_054401 {REF} {Length: 764} {RNA1310_46059} {RNA815_59068} |
|
15. | MligTC455_53075 | 169 | 3.52 | Mlig455_032794 | Neo: - Age: - Region-enriched R8: 4.022/0.00674 Regeneration-downregulated BL: -7.797 Regeneration-depleted BL: -7.797 |
NTN1 | 0.953 | - | 0.953 | - | - | - | - | Mlig455_032794 {REF} {Length: 1705} {Pfam: Laminin EGF domain [PF00053.26, score=66.0]} {Human: ENSG00000065320, NTN1, netrin 1, [Score=125, Expect=4e-31]; ENSG00000162068, NTN3, netrin 3, [Score=120, Expect=9e-30]} {Mouse: ENSMUSG00000020902, Ntn1, netrin 1, [Score=123, Expect=9e-31]; ENSMUSG00000117406, Ntn3, netrin 3, [Score=119, Expect=2e-29]; ENSMUSG00000070564, Ntn5, netrin 5, [Score=118, Expect=8e-30]} {Dmel: FBgn0015774, NetB, Netrin-B, [Score=123, Expect=8e-31]} {Celegans: WBGene00006746, unc-6, Netrin unc-6, [Score=117, Expect=1e-28]} {Smed: dd_Smed_v6_9795_0_1, dd_Smed_v6_9795_0_1, [Score=127, Expect=2e-32]} {RNA1310_21656} {RNA815_31734} |
16. | MligTC455_40522 | 114 | 2.38 | Mlig455_047004, Mlig455_047037 | Neo: - |
ANGPTL3 | 0.952 | - | 0.952 | - | - | - | - | Mlig455_047004 {REF} {Length: 1341} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=62.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=57.0, Expect=8e-09]} {Mouse: ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=52.0, Expect=2e-07]} {Dmel: FBgn0031804, CG9500, [Score=71.2, Expect=2e-14]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=50.1, Expect=6e-07]} {RNA1509_53291} {RNA1310_30694.1} {RNA815_9881} Mlig455_047037 {REF} {Length: 1945} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=60.2]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=58.9, Expect=8e-09]} {Mouse: ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=53.1, Expect=4e-07]} {Dmel: FBgn0031804, CG9500, [Score=72.8, Expect=4e-14]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=53.5, Expect=1e-07]} {RNA1509_53291} {RNA1310_30694.1} {RNA815_9881} |
17. | MligTC455_08876 | 159 | 3.32 | Mlig455_040760 | Neo: - Age: Down-Down-Up |
MPP5 | 0.95 | - | - | 0.950 | - | - | - | Mlig455_040760 {REF} {Length: 1657} {Pfam: Guanylate kinase [PF00625.23, score=71.8]; SH3 domain [PF00018.30, score=38.7]; Variant SH3 domain [PF07653.19, score=32.1]; PDZ domain [PF00595.26, score=24.6]; PDZ domain [PF17820.3, score=20.8]; Variant SH3 domain [PF14604.8, score=20.4]} {Human: ENSG00000072415, MPP5, membrane palmitoylated protein 5, [Score=180, Expect=1e-49]} {Mouse: ENSMUSG00000021112, Mpp5, membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5), [Score=179, Expect=1e-49]} {Dmel: FBgn0050021, metro, menage a trois, [Score=158, Expect=7e-43]} {Celegans: WBGene00002991, lin-2, [Score=161, Expect=1e-43]} {Smed: dd_Smed_v6_7723_0_4, dd_Smed_v6_7723_0_4, [Score=144, Expect=3e-37]} {RNA1509_32149} {RNA1310_16841} {RNA815_8152} |