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Results for MligTC455_42450

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_42450 191 3.98 Mlig455_044139

Neo: -

Age: logFC(26M/2M)=0.453

MRAS Mlig455_044139 {REF} {Length: 2133} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=343.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=136.1]; ADP-ribosylation factor family [PF00025.23, score=68.1]; Elongation factor Tu GTP binding domain [PF00009.29, score=67.4]; 50S ribosome-binding GTPase [PF01926.25, score=41.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=31.1]; RsgA GTPase [PF03193.18, score=27.3]; Septin [PF00735.20, score=23.8]; NB-ARC domain [PF00931.24, score=23.3]; AAA ATPase domain [PF13191.8, score=21.1]; Conserved hypothetical ATP binding protein [PF03029.19, score=19.7]; NUBPL iron-transfer P-loop NTPase [PF10609.11, score=18.8]} {Human: ENSG00000158186, MRAS, muscle RAS oncogene homolog, [RH, Score=237, Expect=1e-76]} {Mouse: ENSMUSG00000032470, Mras, muscle and microspikes RAS, [RH, Score=237, Expect=1e-76]} {Dmel: FBgn0003206, Ras64B, Ras oncogene at 64B, [Score=174, Expect=8e-53]} {Celegans: WBGene00004311, ras-2, GTP binding protein; R-RAS related, [RH, Score=240, Expect=3e-78]} {Smed: dd_Smed_v6_8100_0_2, dd_Smed_v6_8100_0_2, [RH, Score=209, Expect=7e-66]} {RNA1509_34936} {RNA1310_19797} {RNA815_1221.1}

Cumulative graph for MligTC455_42450

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.957 2.64 0.14821 0.76192
RegionR2 0.44 2.64 0.65178 0.98639
RegionR3 0.851 2.64 0.32992 0.86790
RegionR4 0.73 2.64 0.46228 0.78992
RegionR5 1.209 2.64 0.10787 0.32116
RegionR6 0.858 2.64 0.33689 0.92425
RegionR7 1.073 2.64 0.27592 0.90690
RegionR8 0.796 2.64 0.49385 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.121 2.64 1.00000 1.00000
RegenerationR2 -0.25 2.64 0.64175 0.93203
RegenerationR3 -0.936 2.64 0.13075 0.55402
RegenerationR4 -0.461 2.64 0.47631 0.85666
RegenerationR5 -0.229 2.64 0.66791 0.93987
RegenerationR6 -0.659 2.64 0.30207 0.65158
RegenerationBL -1.344 2.64 0.12859 0.42676
RegenerationTP -1.299 2.64 0.15135 0.57605


Genes with expression patterns similar to MligTC455_42450

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_42450 191 3.98 Mlig455_044139

Neo: -

Age: logFC(26M/2M)=0.453

MRAS 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_044139 {REF} {Length: 2133} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=343.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=136.1]; ADP-ribosylation factor family [PF00025.23, score=68.1]; Elongation factor Tu GTP binding domain [PF00009.29, score=67.4]; 50S ribosome-binding GTPase [PF01926.25, score=41.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=31.1]; RsgA GTPase [PF03193.18, score=27.3]; Septin [PF00735.20, score=23.8]; NB-ARC domain [PF00931.24, score=23.3]; AAA ATPase domain [PF13191.8, score=21.1]; Conserved hypothetical ATP binding protein [PF03029.19, score=19.7]; NUBPL iron-transfer P-loop NTPase [PF10609.11, score=18.8]} {Human: ENSG00000158186, MRAS, muscle RAS oncogene homolog, [RH, Score=237, Expect=1e-76]} {Mouse: ENSMUSG00000032470, Mras, muscle and microspikes RAS, [RH, Score=237, Expect=1e-76]} {Dmel: FBgn0003206, Ras64B, Ras oncogene at 64B, [Score=174, Expect=8e-53]} {Celegans: WBGene00004311, ras-2, GTP binding protein; R-RAS related, [RH, Score=240, Expect=3e-78]} {Smed: dd_Smed_v6_8100_0_2, dd_Smed_v6_8100_0_2, [RH, Score=209, Expect=7e-66]} {RNA1509_34936} {RNA1310_19797} {RNA815_1221.1}
2. MligTC455_31550 339 7.07 Mlig455_057441

Neo: -

Age: -

RBM10 0.971 - - - 0.971 - - Mlig455_057441 {REF} {Length: 3693} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=48.9]; OCRE domain [PF17780.3, score=47.3]; G-patch domain [PF01585.25, score=44.7]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=19.3]} {Human: ENSG00000182872, RBM10, RNA binding motif protein 10, [RH, Score=328, Expect=1e-96]} {Mouse: ENSMUSG00000031060, Rbm10, RNA binding motif protein 10, [RH, Score=330, Expect=7e-98]} {Dmel: FBgn0031319, CG4896, [RH, Score=296, Expect=7e-86]} {Celegans: WBGene00020346, rbm-5, RNA Binding Motif protein homolog, [RH, Score=115, Expect=6e-26]} {Smed: dd_Smed_v6_2392_0_4, dd_Smed_v6_2392_0_4, [RH, Score=208, Expect=8e-56]} {RNA1509_10003} {RNA1310_1240.1} {RNA815_5113}
3. MligTC455_32493 777 16.2 Mlig455_022632

Neo: -

Age: -

Region-enriched R5: 1.296/0.01419

0.963 - - - - 0.963 - Mlig455_022632 {REF} {Length: 224} {NoTransDecoderORF} {RNA1509_16305} {RNA1310_27778.1} {RNA815_7035}
4. MligTC455_20065 1482 30.87 Mlig455_000221, Mlig455_058479

Neo: -

Age: Down-Up-Up

PIGW 0.961 - - - - 0.961 -

Mlig455_000221 {REF} {Length: 2066} {TRANSSPLICED} {Pfam: GWT1 [PF06423.14, score=72.6]} {Human: ENSG00000277161, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=79.0, Expect=1e-14]; ENSG00000275600, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=79.0, Expect=1e-14]} {Mouse: ENSMUSG00000045140, Pigw, phosphatidylinositol glycan anchor biosynthesis, class W, [Score=100, Expect=1e-21]} {Dmel: FBgn0031422, PIG-Wa, Phosphatidylinositol glycan anchor biosynthesis class W a, [Score=115, Expect=4e-27]} {Celegans: WBGene00022447, hpo-20, Phosphatidylinositol-glycan biosynthesis class W protein, [Score=106, Expect=5e-24]} {Smed: dd_Smed_v6_14190_0_1, dd_Smed_v6_14190_0_1, [Score=120, Expect=6e-29]} {RNA1509_19464, RNA1509_29630} {RNA1310_6153, RNA1509_19464, RNA1509_29630} {RNA1509_19464, RNA1509_29630, RNA815_7740}

Mlig455_058479 {REF} {Length: 2310} {Pfam: GWT1 [PF06423.14, score=70.1]} {Human: ENSG00000277161, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=74.3, Expect=2e-13]; ENSG00000275600, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=74.3, Expect=2e-13]} {Mouse: ENSMUSG00000045140, Pigw, phosphatidylinositol glycan anchor biosynthesis, class W, [Score=96.7, Expect=1e-20]} {Dmel: FBgn0031422, PIG-Wa, Phosphatidylinositol glycan anchor biosynthesis class W a, [Score=113, Expect=2e-26]} {Celegans: WBGene00022447, hpo-20, Phosphatidylinositol-glycan biosynthesis class W protein, [Score=102, Expect=6e-23]} {Smed: dd_Smed_v6_14190_0_1, dd_Smed_v6_14190_0_1, [Score=119, Expect=1e-28]} {RNA1509_19464} {RNA1310_6153} {RNA815_7740}
5. MligTC455_30708 801 16.68 Mlig455_029611

Neo: Germline

Age: -

ALDH18A1 0.961 - - - - 0.961 - Mlig455_029611 {REF} {Length: 2935} {TRANSSPLICED} {Pfam: Amino acid kinase family [PF00696.30, score=136.1]; Aldehyde dehydrogenase family [PF00171.24, score=55.9]} {Human: ENSG00000059573, ALDH18A1, aldehyde dehydrogenase 18 family member A1, [RH, Score=845, Expect=0.0]} {Mouse: ENSMUSG00000025007, Aldh18a1, aldehyde dehydrogenase 18 family, member A1, [RH, Score=858, Expect=0.0]} {Dmel: FBgn0037146, CG7470, [RH, Score=809, Expect=0.0]} {Celegans: WBGene00011938, alh-13, Probable delta-1-pyrroline-5-carboxylate synthase Glutamate 5-kinase Gamma-glutamyl phosphate reductase, [RH, Score=810, Expect=0.0]} {Smed: dd_Smed_v6_1060_0_1, dd_Smed_v6_1060_0_1, [RH, Score=908, Expect=0.0]} {RNA1509_1671} {RNA1310_2413} {RNA815_1917}
6. MligTC455_28935 350 7.3 Mlig455_001893

Neo: Int S/G2/M

Age: logFC(26M/2M)=-0.374

0.959 - - - - 0.959 - Mlig455_001893 {REF} {Length: 1894} {Pfam: Universal stress protein family [PF00582.28, score=78.8]} {Smed: dd_Smed_v6_1092_0_1, dd_Smed_v6_1092_0_1, [Score=112, Expect=2e-32]} {RNA1509_16808, RNA1509_2764, RNA1509_31626} {RNA1310_13748, RNA1509_16808, RNA1509_31626} {RNA1509_16808, RNA1509_31626, RNA815_17818.1}
7. MligTC455_18654 497 10.36 Mlig455_032693

Neo: -

Age: -

PPME1 0.954 - - - - - 0.954 Mlig455_032693 {REF} {Length: 2557} {TRANSSPLICED} {Pfam: Alpha/beta hydrolase family [PF12697.9, score=84.1]; alpha/beta hydrolase fold [PF00561.22, score=34.3]; Serine aminopeptidase, S33 [PF12146.10, score=30.6]; alpha/beta hydrolase fold [PF07859.15, score=20.5]; PGAP1-like protein [PF07819.15, score=19.9]} {Human: ENSG00000214517, PPME1, protein phosphatase methylesterase 1, [RH, Score=273, Expect=6e-87]} {Mouse: ENSMUSG00000030718, Ppme1, protein phosphatase methylesterase 1, [RH, Score=157, Expect=3e-43]} {Dmel: FBgn0035951, CG5068, [RH, Score=262, Expect=6e-83]} {Celegans: WBGene00007188, B0464.9, Probable protein phosphatase methylesterase 1, [RH, Score=147, Expect=4e-40]} {Smed: dd_Smed_v6_5813_0_1, dd_Smed_v6_5813_0_1, [RH, Score=291, Expect=1e-94]} {RNA1509_18678, RNA1509_50525} {RNA1310_14476, RNA1509_50525} {RNA1509_50525, RNA815_3742.1}
8. MligTC455_46238 222 4.62 Mlig455_040297

Neo: -

Age: -

DNM1L 0.952 - - - - 0.952 - Mlig455_040297 {REF} {Length: 2254} {Pfam: Dynamin central region [PF01031.22, score=329.6]; Dynamin family [PF00350.25, score=174.2]; Dynamin GTPase effector domain [PF02212.20, score=107.0]} {Human: ENSG00000087470, DNM1L, dynamin 1 like, [Score=873, Expect=0.0]} {Mouse: ENSMUSG00000022789, Dnm1l, dynamin 1-like, [Score=867, Expect=0.0]} {Dmel: FBgn0026479, Drp1, Dynamin related protein 1, [Score=853, Expect=0.0]} {Celegans: WBGene00001093, drp-1, Dynamin-Related Protein; Dynamin-related protein, [Score=789, Expect=0.0]} {Smed: dd_Smed_v6_1818_0_1, dd_Smed_v6_1818_0_1, [Score=654, Expect=0.0]} {RNA1509_49692} {RNA1310_7022} {RNA815_5974}
9. MligTC455_18272 1198 24.97 Mlig455_027206, Mlig455_050662

Neo: -

Age: -

CUL5 0.951 - - - 0.951 - -

Mlig455_027206 {REF} {Length: 4677} {TRANSSPLICED} {Pfam: Cullin family [PF00888.24, score=599.7]; Cullin protein neddylation domain [PF10557.11, score=65.1]} {Human: ENSG00000166266, CUL5, cullin 5, [RH, Score=1004, Expect=0.0]} {Mouse: ENSMUSG00000032030, Cul5, cullin 5, [RH, Score=998, Expect=0.0]} {Dmel: FBgn0039632, Cul5, Cullin 5, [RH, Score=792, Expect=0.0]} {Celegans: WBGene00000840, cul-5, Cullin-5, [RH, Score=706, Expect=0.0]} {Smed: dd_Smed_v6_8238_0_1, dd_Smed_v6_8238_0_1, [RH, Score=813, Expect=0.0]} {RNA1509_7097} {RNA1310_5798.1, RNA1509_7097} {RNA1509_7097, RNA815_1237.1}

Mlig455_050662 {REF} {Length: 3918} {TRANSSPLICED} {Pfam: Cullin family [PF00888.24, score=599.2]; Cullin protein neddylation domain [PF10557.11, score=65.1]} {Human: ENSG00000166266, CUL5, cullin 5, [RH, Score=1003, Expect=0.0]} {Mouse: ENSMUSG00000032030, Cul5, cullin 5, [RH, Score=998, Expect=0.0]} {Dmel: FBgn0039632, Cul5, Cullin 5, [RH, Score=792, Expect=0.0]} {Celegans: WBGene00000840, cul-5, Cullin-5, [RH, Score=706, Expect=0.0]} {Smed: dd_Smed_v6_8238_0_1, dd_Smed_v6_8238_0_1, [RH, Score=813, Expect=0.0]} {RNA1509_7097} {RNA1310_5798.1} {RNA815_1237.1}

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