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Results for MligTC455_42654

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_42654 39 0.81 Mlig455_004817, Mlig455_004898

Neo: -

Age: Up-Down-Up

Regeneration-enriched R6: 11.200
Regeneration-enriched R5: 10.874
Regeneration-enriched R2: 9.867

LMLN2

Mlig455_004817 {REF} {Length: 3344} {Pfam: Leishmanolysin [PF01457.18, score=40.1]} {Human: ENSG00000283654, LMLN2, leishmanolysin like peptidase 2, [RH, Score=92.0, Expect=1e-18]} {Mouse: ENSMUSG00000114865, Gm29776, predicted gene, 29776, [RH, Score=88.2, Expect=2e-17]} {Dmel: FBgn0086359, Invadolysin, [Score=75.5, Expect=1e-13]} {Celegans: WBGene00012796, Y43F4A.1, Leishmanolysin-like peptidase, [Score=68.9, Expect=8e-12]} {Smed: dd_Smed_v6_9167_0_1, dd_Smed_v6_9167_0_1, [Score=75.5, Expect=7e-14]} {RNA1509_37538} {RNA1310_4126} {RNA815_1195}

Mlig455_004898 {REF} {Length: 3341} {Pfam: Leishmanolysin [PF01457.18, score=40.4]} {Human: ENSG00000283654, LMLN2, leishmanolysin like peptidase 2, [RH, Score=92.0, Expect=1e-18]} {Mouse: ENSMUSG00000114865, Gm29776, predicted gene, 29776, [RH, Score=89.0, Expect=1e-17]} {Dmel: FBgn0086359, Invadolysin, [Score=74.7, Expect=2e-13]} {Celegans: WBGene00012796, Y43F4A.1, Leishmanolysin-like peptidase, [Score=69.3, Expect=8e-12]} {Smed: dd_Smed_v6_9167_0_1, dd_Smed_v6_9167_0_1, [Score=75.9, Expect=6e-14]} {RNA1509_37538} {RNA1310_4126} {RNA815_1195}

Cumulative graph for MligTC455_42654

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -3.474 1.131 0.99990 1.00000
RegionR2 6.036 1.131 0.99981 1.00000
RegionR3 0.96 1.131 0.99996 1.00000
RegionR4 -4.76 1.131 0.99987 1.00000
RegionR5 -1.58 1.131 0.99993 1.00000
RegionR6 0.47 1.131 0.99996 1.00000
RegionR7 0.462 1.131 0.99996 1.00000
RegionR8 1.886 1.131 0.99996 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 11.857 1.131 0.99995 1.00000
RegenerationR2 9.867 1.131 0.00000 0.00000
RegenerationR3 11.626 1.131 0.99959 1.00000
RegenerationR4 12.478 1.131 1.00000 1.00000
RegenerationR5 10.874 1.131 0.00002 0.00488
RegenerationR6 11.2 1.131 0.00000 0.00046
RegenerationBL 7.025 1.131 0.99992 1.00000
RegenerationTP 10.014 1.131 0.00011 0.01262


Genes with expression patterns similar to MligTC455_42654

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_42654 39 0.81 Mlig455_004817, Mlig455_004898

Neo: -

Age: Up-Down-Up

Regeneration-enriched R6: 11.200
Regeneration-enriched R5: 10.874
Regeneration-enriched R2: 9.867

LMLN2 1 - - - - - 1.000

Mlig455_004817 {REF} {Length: 3344} {Pfam: Leishmanolysin [PF01457.18, score=40.1]} {Human: ENSG00000283654, LMLN2, leishmanolysin like peptidase 2, [RH, Score=92.0, Expect=1e-18]} {Mouse: ENSMUSG00000114865, Gm29776, predicted gene, 29776, [RH, Score=88.2, Expect=2e-17]} {Dmel: FBgn0086359, Invadolysin, [Score=75.5, Expect=1e-13]} {Celegans: WBGene00012796, Y43F4A.1, Leishmanolysin-like peptidase, [Score=68.9, Expect=8e-12]} {Smed: dd_Smed_v6_9167_0_1, dd_Smed_v6_9167_0_1, [Score=75.5, Expect=7e-14]} {RNA1509_37538} {RNA1310_4126} {RNA815_1195}

Mlig455_004898 {REF} {Length: 3341} {Pfam: Leishmanolysin [PF01457.18, score=40.4]} {Human: ENSG00000283654, LMLN2, leishmanolysin like peptidase 2, [RH, Score=92.0, Expect=1e-18]} {Mouse: ENSMUSG00000114865, Gm29776, predicted gene, 29776, [RH, Score=89.0, Expect=1e-17]} {Dmel: FBgn0086359, Invadolysin, [Score=74.7, Expect=2e-13]} {Celegans: WBGene00012796, Y43F4A.1, Leishmanolysin-like peptidase, [Score=69.3, Expect=8e-12]} {Smed: dd_Smed_v6_9167_0_1, dd_Smed_v6_9167_0_1, [Score=75.9, Expect=6e-14]} {RNA1509_37538} {RNA1310_4126} {RNA815_1195}
2. MligTC455_04625 54 1.12 Mlig455_031551, Mlig455_031554

Neo: -

Age: -

FHAD1 0.98 - - - - - 0.980

Mlig455_031551 {REF} {Length: 1252} {Pfam: FHA domain [PF00498.28, score=38.1]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.3]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=66.2, Expect=1e-11]} {RNA1509_11172} {RNA1310_2117.1} {RNA815_31030}

Mlig455_031554 {REF} {Length: 5287} {Pfam: FHA domain [PF00498.28, score=36.7]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.0]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [Score=130, Expect=4e-31]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=129, Expect=1e-29]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=129, Expect=1e-29]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=252, Expect=3e-68]} {RNA1509_11172} {RNA1310_2117.1} {RNA815_6949}
3. MligTC455_27768 299 6.24 Mlig455_035713, Mlig455_035799

Neo: -

Age: -

IFT74 0.977 - - - - - 0.977

Mlig455_035713 {REF} {Length: 2970} {Human: ENSG00000096872, IFT74, intraflagellar transport 74, [Score=249, Expect=1e-76]} {Mouse: ENSMUSG00000028576, Ift74, intraflagellar transport 74, [Score=266, Expect=1e-83]} {Smed: dd_Smed_v6_12702_0_1, dd_Smed_v6_12702_0_1, [Score=297, Expect=6e-96]} {RNA1509_13394} {RNA1310_14627.2} {RNA815_5880}

Mlig455_035799 {REF} {Length: 3032} {Human: ENSG00000096872, IFT74, intraflagellar transport 74, [RH, Score=441, Expect=3e-148]} {Mouse: ENSMUSG00000028576, Ift74, intraflagellar transport 74, [RH, Score=447, Expect=8e-151]} {Celegans: WBGene00016005, ift-74, IFT (Chlamydomonas IntraFlagellar Transport) homolog, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_12702_0_1, dd_Smed_v6_12702_0_1, [RH, Score=502, Expect=4e-173]} {RNA1509_13394} {RNA1310_14627.2, RNA1509_13394} {RNA1509_13394, RNA815_5880}
4. MligTC455_15655 194 4.05 Mlig455_026918, Mlig455_027074

Neo: -

Age: -

TTC23 0.974 - - - - - 0.974

Mlig455_026918 {REF} {Length: 2631} {Pfam: Tetratricopeptide repeat [PF13424.8, score=76.6]; Tetratricopeptide repeat [PF13374.8, score=53.8]; Tetratricopeptide repeat [PF00515.30, score=40.6]; Tetratricopeptide repeat [PF13181.8, score=22.9]; Tetratricopeptide repeat [PF13176.8, score=22.3]; Tetratricopeptide repeat [PF07719.19, score=19.6]; MalT-like TPR region [PF17874.3, score=18.6]} {Human: ENSG00000103852, TTC23, tetratricopeptide repeat domain 23, [RH, Score=147, Expect=3e-38]} {Mouse: ENSMUSG00000030555, Ttc23, tetratricopeptide repeat domain 23, [RH, Score=159, Expect=2e-42]} {Smed: dd_Smed_v6_15795_0_1, dd_Smed_v6_15795_0_1, [RH, Score=199, Expect=6e-58]} {RNA1509_10212, RNA1509_43344} {RNA1310_7447.1, RNA1509_10212} {RNA1509_10212, RNA815_1983}

Mlig455_027074 {REF} {Length: 2902} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=82.0]; Tetratricopeptide repeat [PF13374.8, score=58.0]; Tetratricopeptide repeat [PF00515.30, score=41.0]; Tetratricopeptide repeat [PF13181.8, score=23.3]; Tetratricopeptide repeat [PF13176.8, score=22.7]; Tetratricopeptide repeat [PF07719.19, score=20.1]; MalT-like TPR region [PF17874.3, score=18.4]} {Human: ENSG00000103852, TTC23, tetratricopeptide repeat domain 23, [RH, Score=148, Expect=2e-38]} {Mouse: ENSMUSG00000030555, Ttc23, tetratricopeptide repeat domain 23, [RH, Score=159, Expect=1e-42]} {Smed: dd_Smed_v6_15795_0_1, dd_Smed_v6_15795_0_1, [RH, Score=203, Expect=1e-59]} {RNA1509_43344} {RNA1310_7447.1} {RNA815_1983}
5. MligTC455_39665 112 2.33 Mlig455_023730

Neo: -

Age: -

EPHA7 0.974 - - - - - 0.974 Mlig455_023730 {REF} {Length: 3591} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.8]; Protein kinase domain [PF00069.27, score=130.1]; Ephrin receptor ligand binding domain [PF01404.21, score=107.2]; Fibronectin type III domain [PF00041.23, score=95.6]; Ephrin type-A receptor 2 transmembrane domain [PF14575.8, score=57.6]; SAM domain (Sterile alpha motif) [PF07647.19, score=55.1]; SAM domain (Sterile alpha motif) [PF00536.32, score=50.6]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.9]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=19.2]} {Human: ENSG00000135333, EPHA7, EPH receptor A7, [Score=658, Expect=0.0]; ENSG00000145242, EPHA5, EPH receptor A5, [Score=647, Expect=0.0]; ENSG00000116106, EPHA4, EPH receptor A4, [Score=646, Expect=0.0]} {Mouse: ENSMUSG00000028289, Epha7, Eph receptor A7, [Score=659, Expect=0.0]; ENSMUSG00000026235, Epha4, Eph receptor A4, [Score=651, Expect=0.0]; ENSMUSG00000029245, Epha5, Eph receptor A5, [Score=648, Expect=0.0]} {Dmel: FBgn0025936, Eph, Eph receptor tyrosine kinase, [Score=609, Expect=0.0]} {Celegans: WBGene00006868, vab-1, Ephrin receptor 1, [Score=458, Expect=2e-143]} {Smed: dd_Smed_v6_16928_0_1, dd_Smed_v6_16928_0_1, [Score=552, Expect=7e-180]} {RNA1509_24016} {RNA1310_2298.1} {RNA815_19987}
6. MligTC455_28509 143 2.97 Mlig455_050246

Neo: -

Age: logFC(26M/2M)=-0.382

WDR49 0.973 - - - - - 0.973 Mlig455_050246 {REF} {Length: 5989} {Pfam: WD domain, G-beta repeat [PF00400.34, score=43.1]; EF-hand domain pair [PF13499.8, score=28.7]; Nup133 N terminal like [PF08801.13, score=22.4]; EF-hand domain pair [PF13833.8, score=21.5]; EF hand [PF00036.34, score=20.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=329, Expect=3e-96]} {Mouse: ENSMUSG00000044083, Efcab8, EF-hand calcium binding domain 8, [RH, Score=258, Expect=2e-70]} {Dmel: FBgn0267449, WDY, WD40 Y, [RH, Score=197, Expect=3e-51]} {Celegans: WBGene00010572, wdr-5.2, WD repeat-containing protein wdr-5.2, [Score=53.9, Expect=4e-07]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=302, Expect=2e-86]} {RNA1509_11289, RNA1509_17402, RNA1509_54041} {RNA1310_2314.2, RNA1509_11289, RNA1509_17402, RNA1509_54041} {RNA1509_11289, RNA1509_17402, RNA1509_54041, RNA815_2581}
7. MligTC455_30730 121 2.52 Mlig455_010096

Neo: -

Age: Up-Down-Down

CACNA1H 0.973 - - - - - 0.973 Mlig455_010096 {REF} {Length: 5627} {Pfam: Ion transport protein [PF00520.33, score=445.4]; Polycystin cation channel [PF08016.14, score=60.4]; Domain of unknown function (DUF4834) [PF16118.7, score=22.5]; FAM176 family [PF14851.8, score=20.1]} {Human: ENSG00000196557, CACNA1H, calcium voltage-gated channel subunit alpha1 H, [RH, Score=748, Expect=0.0]; ENSG00000100346, CACNA1I, calcium voltage-gated channel subunit alpha1 I, [RH, Score=734, Expect=0.0]} {Mouse: ENSMUSG00000024112, Cacna1h, calcium channel, voltage-dependent, T type, alpha 1H subunit, [Score=870, Expect=0.0]} {Dmel: FBgn0264386, Ca-alpha1T, Ca[2+]-channel protein alpha[[1]] subunit T, [RH, Score=868, Expect=0.0]} {Celegans: WBGene00000367, cca-1, Voltage-dependent T-type calcium channel subunit alpha, [RH, Score=774, Expect=0.0]} {Smed: dd_Smed_v6_14730_0_1, dd_Smed_v6_14730_0_1, [Score=1018, Expect=0.0]} {RNA1509_27261, RNA1509_28376} {RNA1310_7416.1, RNA1509_27261, RNA1509_28376} {RNA1509_27261, RNA1509_28376, RNA815_3853}
8. MligTC455_31318 45 0.94 Mlig455_026755

Neo: -

Age: -

0.969 - - - - - 0.969 Mlig455_026755 {REF} {Length: 904} {NoTransDecoderORF} {RNA1509_32637} {RNA1310_14078} {RNA815_15623}
9. MligTC455_33568 93 1.95 Mlig455_011307, Mlig455_061133

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.203/0.00426
Region-enriched R3: 4.071/0.01469
Region-enriched R6: 3.998/0.03526

CNBP 0.965 - - - - - 0.965

Mlig455_011307 {REF} {Length: 1231} {RNA1310_23033.1} {RNA815_15683.1}

Mlig455_061133 {REF} {Length: 2986} {Pfam: RNase H-like domain found in reverse transcriptase [PF17917.3, score=102.2]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=77.0]; Integrase zinc binding domain [PF17921.3, score=24.3]; Zinc knuckle [PF00098.25, score=22.3]} {Human: ENSG00000169714, CNBP, CCHC-type zinc finger nucleic acid binding protein, [Score=50.1, Expect=2e-06]} {Mouse: ENSMUSG00000061186, Sfmbt2, Scm-like with four mbt domains 2, [Score=66.2, Expect=1e-10]} {Smed: dd_Smed_v6_15498_0_18, dd_Smed_v6_15498_0_18, [Score=95.1, Expect=6e-21]} {RNA1509_38544} {RNA1310_23033.1} {RNA815_15683.1}
10. MligTC455_40129 89 1.85 Mlig455_054892

Neo: -

Age: Up-Down-Up

0.964 - - - - - 0.964 Mlig455_054892 {REF} {Length: 2122} {RNA1509_55498} {RNA1310_44145} {RNA815_38949}
11. MligTC455_16760 96 2 Mlig455_039271

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.283/0.01201

CDKL2 0.963 - - - - - 0.963 Mlig455_039271 {REF} {Length: 4664} {Pfam: Protein kinase domain [PF00069.27, score=242.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=123.9]; ABC1 atypical kinase-like domain [PF03109.18, score=17.9]} {Human: ENSG00000138769, CDKL2, cyclin dependent kinase like 2, [RH, Score=445, Expect=3e-150]} {Mouse: ENSMUSG00000029403, Cdkl2, cyclin-dependent kinase-like 2 (CDC2-related kinase), [RH, Score=427, Expect=3e-143]} {Dmel: FBgn0031730, CG7236, [Score=332, Expect=3e-108]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=337, Expect=1e-111]} {Smed: dd_Smed_v6_17162_0_1, dd_Smed_v6_17162_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_31808} {RNA1310_11068.1} {RNA815_5716}
12. MligTC455_16952 79 1.65 Mlig455_001182

Neo: -

Age: -

0.962 - - - - - 0.962 Mlig455_001182 {REF} {Length: 3873} {Smed: dd_Smed_v6_17523_0_1, dd_Smed_v6_17523_0_1, [RH, Score=67.0, Expect=3e-14]} {RNA1509_4618} {RNA1310_46281} {RNA815_28578}
13. MligTC455_38810 655 13.64 Mlig455_021157, Mlig455_021360, Mlig455_021587

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.289

Region-enriched R2: 2.927/0.00001

NELL2 0.962 - - - - - 0.962

Mlig455_021157 {REF} {Length: 4103} {Smed: dd_Smed_v6_13075_0_2, dd_Smed_v6_13075_0_2, [Score=57.8, Expect=4e-08]} {RNA1509_22586} {RNA1310_1033} {RNA815_17785}

Mlig455_021360 {REF} {Length: 7457} {Pfam: Calcium-binding EGF domain [PF07645.17, score=34.6]; EGF domain [PF12947.9, score=33.5]; TNFR/NGFR cysteine-rich region [PF00020.20, score=27.7]; Complement Clr-like EGF-like [PF12662.9, score=20.4]} {Human: ENSG00000184613, NELL2, neural EGFL like 2, [Score=63.5, Expect=4e-09]; ENSG00000168743, NPNT, nephronectin, [Score=62.4, Expect=6e-09]; ENSG00000165973, NELL1, neural EGFL like 1, [Score=60.8, Expect=3e-08]} {Mouse: ENSMUSG00000000402, Egfl6, EGF-like-domain, multiple 6, [Score=63.2, Expect=3e-09]; ENSMUSG00000022454, Nell2, NEL-like 2, [Score=63.2, Expect=3e-09]; ENSMUSG00000002885, Adgre5, adhesion G protein-coupled receptor E5, [Score=62.0, Expect=6e-09]; ENSMUSG00000040998, Npnt, nephronectin, [Score=62.0, Expect=5e-09]} {Dmel: FBgn0035798, frac, faulty attraction, [Score=54.7, Expect=1e-06]} {Celegans: WBGene00022816, fbn-1, FBN-1A.1; FiBrilliN homolog, [Score=68.9, Expect=4e-11]} {Smed: dd_Smed_v6_13075_0_1, dd_Smed_v6_13075_0_1, [RH, Score=146, Expect=9e-35]} {RNA1509_49441} {RNA1310_699, RNA1509_49441} {RNA1509_49441, RNA815_6324}

Mlig455_021587 {REF} {Length: 2362} {RNA1509_22586} {RNA1310_1033} {RNA815_22832}
14. MligTC455_39664 122 2.55 Mlig455_023719, Mlig455_023723

Neo: -

Age: -

EPHA2, EPHA7 0.962 - - - - - 0.962

Mlig455_023719 {REF} {Length: 1150} {TRANSSPLICED} {Pfam: Ephrin receptor ligand binding domain [PF01404.21, score=109.7]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=25.3]; Giardia variant-specific surface protein [PF03302.15, score=17.7]} {Human: ENSG00000142627, EPHA2, EPH receptor A2, [Score=164, Expect=4e-44]} {Mouse: ENSMUSG00000006445, Epha2, Eph receptor A2, [Score=159, Expect=3e-42]} {Celegans: WBGene00006868, vab-1, Ephrin receptor 1, [Score=86.7, Expect=4e-18]} {Smed: dd_Smed_v6_16928_0_1, dd_Smed_v6_16928_0_1, [Score=155, Expect=2e-41]} {RNA1509_51951} {RNA1310_2298.1} {RNA815_18224.1}

Mlig455_023723 {REF} {Length: 5114} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.8]; Protein kinase domain [PF00069.27, score=130.1]; Ephrin receptor ligand binding domain [PF01404.21, score=107.2]; Fibronectin type III domain [PF00041.23, score=95.6]; Ephrin type-A receptor 2 transmembrane domain [PF14575.8, score=57.6]; SAM domain (Sterile alpha motif) [PF07647.19, score=55.1]; SAM domain (Sterile alpha motif) [PF00536.32, score=50.6]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.9]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=19.2]} {Human: ENSG00000135333, EPHA7, EPH receptor A7, [Score=658, Expect=0.0]; ENSG00000145242, EPHA5, EPH receptor A5, [Score=647, Expect=0.0]; ENSG00000116106, EPHA4, EPH receptor A4, [Score=646, Expect=0.0]} {Mouse: ENSMUSG00000028289, Epha7, Eph receptor A7, [Score=659, Expect=0.0]; ENSMUSG00000026235, Epha4, Eph receptor A4, [Score=651, Expect=0.0]; ENSMUSG00000029245, Epha5, Eph receptor A5, [Score=648, Expect=0.0]} {Dmel: FBgn0025936, Eph, Eph receptor tyrosine kinase, [Score=609, Expect=0.0]} {Celegans: WBGene00006868, vab-1, Ephrin receptor 1, [Score=458, Expect=2e-143]} {Smed: dd_Smed_v6_16928_0_1, dd_Smed_v6_16928_0_1, [Score=552, Expect=7e-180]} {RNA1509_24016} {RNA1310_2298.1} {RNA815_10575}
15. MligTC455_54517 38 0.78 Mlig455_049988

Neo: -

Age: -

0.962 - - - - - 0.962 Mlig455_049988 {REF} {Length: 738} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_13614.1} {RNA815_15623}
16. MligTC455_33196 60 1.25 Mlig455_044536

Neo: -

Age: -

CAMKK2 0.961 - - - - - 0.961 Mlig455_044536 {REF} {Length: 2791} {Pfam: Protein kinase domain [PF00069.27, score=209.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.7]; Kinase-like [PF14531.8, score=30.4]; Fungal protein kinase [PF17667.3, score=19.2]} {Human: ENSG00000110931, CAMKK2, calcium/calmodulin dependent protein kinase kinase 2, [RH, Score=416, Expect=2e-137]} {Mouse: ENSMUSG00000029471, Camkk2, calcium/calmodulin-dependent protein kinase kinase 2, beta, [RH, Score=407, Expect=8e-135]; ENSMUSG00000020785, Camkk1, calcium/calmodulin-dependent protein kinase kinase 1, alpha, [RH, Score=392, Expect=4e-129]} {Dmel: FBgn0040056, CG17698, [RH, Score=400, Expect=2e-130]} {Celegans: WBGene00000518, ckk-1, Calcium/calmodulin-dependent protein kinase kinase, [RH, Score=412, Expect=7e-137]} {Smed: dd_Smed_v6_18437_0_1, dd_Smed_v6_18437_0_1, [RH, Score=365, Expect=7e-118]} {RNA1509_51718} {RNA1310_7593.1} {RNA815_7566}
17. MligTC455_37314 28 0.59 Mlig455_020645

Neo: -

Age: -

CALM2 0.961 - - - - - 0.961 Mlig455_020645 {REF} {Length: 1006} {Pfam: EF-hand domain pair [PF13499.8, score=22.0]; EF-hand domain [PF14658.8, score=19.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=65.9, Expect=3e-13]; ENSG00000198668, CALM1, calmodulin 1, [Score=65.9, Expect=3e-13]; ENSG00000160014, CALM3, calmodulin 3, [Score=65.9, Expect=3e-13]; ENSG00000178363, CALML3, calmodulin like 3, [Score=65.1, Expect=6e-13]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=66.6, Expect=3e-13]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=65.9, Expect=2e-13]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=65.9, Expect=2e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=67.8, Expect=3e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=67.8, Expect=2e-14]} {Smed: dd_Smed_v6_5491_0_1, dd_Smed_v6_5491_0_1, [Score=109, Expect=5e-30]} {RNA1310_33365} {RNA815_27013}
18. MligTC455_41181 708 14.76 Mlig455_049760

Neo: -

Age: logFC(26M/2M)=-0.377

Region-enriched R2: 2.010/0.02984

AK5 0.961 - - - - - 0.961 Mlig455_049760 {REF} {Length: 2835} {TRANSSPLICED} {Pfam: Adenylate kinase [PF00406.24, score=105.1]; AAA domain [PF13207.8, score=87.6]; AAA domain [PF13238.8, score=49.8]; AAA domain [PF13671.8, score=35.6]; IQ calmodulin-binding motif [PF00612.29, score=33.6]; AAA ATPase domain [PF13191.8, score=29.8]; AAA domain [PF13521.8, score=22.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.4]; AAA domain [PF13245.8, score=20.1]} {Human: ENSG00000154027, AK5, adenylate kinase 5, [RH, Score=223, Expect=6e-64]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [RH, Score=222, Expect=1e-63]} {Dmel: FBgn0032083, CG9541, [RH, Score=109, Expect=1e-24]} {Celegans: WBGene00008746, F13E6.2, [Score=126, Expect=7e-30]} {Smed: dd_Smed_v6_5119_0_1, dd_Smed_v6_5119_0_1, [RH, Score=266, Expect=1e-77]} {RNA1509_14765, RNA1509_30132} {RNA1310_6179.1, RNA1509_14765, RNA1509_30132} {RNA1509_14765, RNA1509_30132, RNA815_3037}
19. MligTC455_49557 280 5.82 Mlig455_017273

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.728

Region-specific R2: 3.642

Region-enriched R2: 3.187/0.00196

0.961 - - - - - 0.961 Mlig455_017273 {REF} {Length: 1333} {RNA1509_52848} {RNA1310_64923, RNA1509_52848} {RNA1509_52848, RNA815_51063}
20. MligTC455_45287 272 5.67 Mlig455_050345, Mlig455_050359

Neo: -

Age: -

FOXJ3 0.96 - - - - - 0.960

Mlig455_050345 {REF} {Length: 2664} {Pfam: Forkhead domain [PF00250.20, score=120.7]} {Human: ENSG00000198815, FOXJ3, forkhead box J3, [Score=134, Expect=1e-33]} {Mouse: ENSMUSG00000032998, Foxj3, forkhead box J3, [Score=133, Expect=1e-33]} {Dmel: FBgn0003430, slp1, sloppy paired 1, [Score=111, Expect=2e-27]} {Celegans: WBGene00001434, fkh-2, ForKHead transcription factor family, [Score=110, Expect=1e-27]} {Smed: dd_Smed_v6_30720_0_1, dd_Smed_v6_30720_0_1, [Score=107, Expect=4e-27]} {RNA1509_33977} {RNA1310_34719} {RNA815_20331}

Mlig455_050359 {REF} {Length: 1950} {Pfam: Forkhead domain [PF00250.20, score=120.7]} {Human: ENSG00000198815, FOXJ3, forkhead box J3, [Score=134, Expect=1e-33]} {Mouse: ENSMUSG00000032998, Foxj3, forkhead box J3, [Score=133, Expect=1e-33]} {Dmel: FBgn0003430, slp1, sloppy paired 1, [Score=111, Expect=2e-27]} {Celegans: WBGene00001434, fkh-2, ForKHead transcription factor family, [Score=110, Expect=1e-27]} {Smed: dd_Smed_v6_30720_0_1, dd_Smed_v6_30720_0_1, [Score=107, Expect=4e-27]} {RNA1509_33977} {RNA1310_49039.1} {RNA815_20331}
21. MligTC455_28100 46 0.95 Mlig455_033369

Neo: -

Age: -

0.959 - - - - - 0.959 Mlig455_033369 {REF} {Length: 1958} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_22299} {RNA815_15623}
22. MligTC455_29874 65 1.36 Mlig455_037947, Mlig455_068699

Neo: -

Age: logFC(26M/2M)=-0.467

ANKRD50 0.959 - - - - - 0.959

Mlig455_037947 {REF} {Length: 4099} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=309.9]; Ankyrin repeat [PF00023.32, score=295.0]; Ankyrin repeat [PF13606.8, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=228.6]; Ankyrin repeats (many copies) [PF13857.8, score=200.7]; Glutamine amidotransferase domain [PF13537.8, score=68.9]; PEGA domain [PF08308.13, score=35.0]; Mab-21 protein [PF03281.16, score=29.5]; Nucleoplasmin/nucleophosmin domain [PF03066.17, score=26.4]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=276, Expect=2e-75]; ENSG00000029534, ANK1, ankyrin 1, [Score=270, Expect=5e-73]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=274, Expect=8e-75]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=256, Expect=7e-69]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=258, Expect=1e-69]} {Smed: dd_Smed_v6_2072_0_29, dd_Smed_v6_2072_0_29, [Score=256, Expect=2e-71]} {RNA1509_26004, RNA1509_28959} {RNA1310_3906.1, RNA1509_28959} {RNA1509_28959, RNA815_1664.1}

Mlig455_068699 {REF} {Length: 2234} {Pfam: Mab-21 protein [PF03281.16, score=31.1]} {RNA1509_26004} {RNA1310_3906.1} {RNA815_1664.1}
23. MligTC455_28202 337 7.03 Mlig455_063876

Neo: -

Age: -

Region-enriched R2: 3.393/0.00249

0.958 - - - - - 0.958 Mlig455_063876 {REF} {Length: 9210} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [Score=102, Expect=3e-23]} {RNA1509_30620, RNA1509_41832, RNA1509_45836} {RNA1310_13656, RNA1509_41832, RNA1509_45836} {RNA1509_41832, RNA1509_45836, RNA815_1450.1}
24. MligTC455_45301 85 1.78 Mlig455_020797

Neo: -

Age: -

0.957 - - - - - 0.957 Mlig455_020797 {REF} {Length: 4496} {Pfam: C2H2-type zinc finger [PF13894.8, score=40.3]; Zinc finger, C2H2 type [PF00096.28, score=26.6]; Cysteine rich domain with multizinc binding regions [PF17979.3, score=22.5]} {Dmel: FBgn0036725, CG18265, [RH, Score=55.5, Expect=3e-07]} {Celegans: WBGene00000995, die-1, Dorsal Intercalation and Elongation defect, [RH, Score=58.9, Expect=2e-08]} {Smed: dd_Smed_v6_34785_0_1, dd_Smed_v6_34785_0_1, [RH, Score=119, Expect=8e-28]} {RNA1509_19455} {RNA1310_2166.1} {RNA815_12667}
25. MligTC455_15420 149 3.1 Mlig455_018025

Neo: -

Age: -

0.956 - - - - - 0.956 Mlig455_018025 {REF} {Length: 2330} {Pfam: Soluble NSF attachment protein, SNAP [PF14938.8, score=129.5]; Maintenance of mitochondrial structure and function [PF13012.8, score=19.7]} {Celegans: WBGene00017016, snap-1, SNAP (Soluble NSF Attachment Protein) homolog, [Score=112, Expect=2e-27]} {Smed: dd_Smed_v6_2480_0_1, dd_Smed_v6_2480_0_1, [Score=103, Expect=1e-24]} {RNA1509_23300} {RNA1310_43559} {RNA815_10646}
26. MligTC455_15421 158 3.29 Mlig455_018040

Neo: -

Age: -

0.955 - - - - - 0.955 Mlig455_018040 {REF} {Length: 1037} {Pfam: Soluble NSF attachment protein, SNAP [PF14938.8, score=60.1]} {RNA1509_34494} {RNA1310_23320} {RNA815_36104}
27. MligTC455_35890 1563 32.56 Mlig455_047529, Mlig455_047538, Mlig455_059662

Neo: -

Age: -

IFT80 0.955 - - - - - 0.955

Mlig455_047529 {REF} {Length: 2724} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=55.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=38.4]} {Human: ENSG00000068885, IFT80, intraflagellar transport 80, [RH, Score=871, Expect=0.0]} {Mouse: ENSMUSG00000027778, Ift80, intraflagellar transport 80, [RH, Score=868, Expect=0.0]} {Dmel: FBgn0032891, Oseg5, Outer segment 5, [RH, Score=447, Expect=7e-146]} {Celegans: WBGene00000484, che-2, CHE-2 protein, [RH, Score=581, Expect=0.0]} {Smed: dd_Smed_v6_9110_0_1, dd_Smed_v6_9110_0_1, [RH, Score=793, Expect=0.0]} {RNA1509_7485} {RNA1310_7061, RNA1509_7485} {RNA1509_7485, RNA815_2221}

Mlig455_047538 {REF} {Length: 2547} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=52.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=35.7]} {Human: ENSG00000068885, IFT80, intraflagellar transport 80, [Score=703, Expect=0.0]} {Mouse: ENSMUSG00000027778, Ift80, intraflagellar transport 80, [Score=703, Expect=0.0]} {Dmel: FBgn0032891, Oseg5, Outer segment 5, [Score=358, Expect=2e-113]} {Celegans: WBGene00000484, che-2, CHE-2 protein, [Score=451, Expect=3e-149]} {Smed: dd_Smed_v6_9110_0_1, dd_Smed_v6_9110_0_1, [Score=620, Expect=0.0]} {RNA1509_7485} {RNA1310_7061} {RNA815_2221}

Mlig455_059662 {REF} {Length: 2718} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=54.8]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=38.1]} {Human: ENSG00000068885, IFT80, intraflagellar transport 80, [RH, Score=871, Expect=0.0]} {Mouse: ENSMUSG00000027778, Ift80, intraflagellar transport 80, [RH, Score=869, Expect=0.0]} {Dmel: FBgn0032891, Oseg5, Outer segment 5, [RH, Score=448, Expect=2e-146]} {Celegans: WBGene00000484, che-2, CHE-2 protein, [RH, Score=581, Expect=0.0]} {Smed: dd_Smed_v6_9110_0_1, dd_Smed_v6_9110_0_1, [RH, Score=794, Expect=0.0]} {RNA1509_7485} {RNA1310_7061} {RNA815_2221}
28. MligTC455_49763 130 2.72 Mlig455_006404

Neo: -

Age: -

Region-enriched R2: 3.029/0.02346

KREMEN1 0.955 - - - - - 0.955 Mlig455_006404 {REF} {Length: 1879} {Pfam: WSC domain [PF01822.21, score=53.7]; PAN domain [PF00024.28, score=24.0]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=45.1, Expect=1e-05]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=44.7, Expect=1e-05]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=47.8, Expect=9e-07]} {RNA1509_53783} {RNA1310_43597} {RNA815_9084.2}
29. MligTC455_51154 45 0.94 Mlig455_045899

Neo: -

Age: -

CPED1 0.955 - - - - - 0.955 Mlig455_045899 {REF} {Length: 3530} {Human: ENSG00000106034, CPED1, cadherin like and PC-esterase domain containing 1, [RH, Score=178, Expect=2e-47]} {Mouse: ENSMUSG00000062980, Cped1, cadherin-like and PC-esterase domain containing 1, [RH, Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_14757_0_1, dd_Smed_v6_14757_0_1, [RH, Score=188, Expect=3e-53]} {RNA1509_12903} {RNA1310_19899.1} {RNA815_44464}
30. MligTC455_15506 219 4.57 Mlig455_025204

Neo: -

Age: logFC(26M/2M)=-0.337

ANKEF1 0.953 - - - - - 0.953 Mlig455_025204 {REF} {Length: 2950} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=181.3]; Ankyrin repeats (many copies) [PF13637.8, score=145.9]; Ankyrin repeats (many copies) [PF13857.8, score=133.7]; Ankyrin repeat [PF00023.32, score=131.5]; Ankyrin repeat [PF13606.8, score=130.5]} {Human: ENSG00000132623, ANKEF1, ankyrin repeat and EF-hand domain containing 1, [RH, Score=531, Expect=7e-178]} {Mouse: ENSMUSG00000074771, Ankef1, ankyrin repeat and EF-hand domain containing 1, [RH, Score=543, Expect=0.0]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=123, Expect=2e-28]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=120, Expect=1e-27]} {Smed: dd_Smed_v6_12476_0_1, dd_Smed_v6_12476_0_1, [RH, Score=731, Expect=0.0]} {RNA1509_36316, RNA1509_7497} {RNA1310_7884.1, RNA1509_36316, RNA1509_7497} {RNA1509_36316, RNA1509_7497, RNA815_1782}
31. MligTC455_19442 244 5.09 Mlig455_002080

Neo: -

Age: logFC(26M/2M)=-0.526

0.953 - - - - - 0.953 Mlig455_002080 {REF} {Length: 2265} {Pfam: Aldehyde ferredoxin oxidoreductase, N-terminal domain [PF02730.17, score=18.6]} {RNA1509_40470} {RNA1310_22476.3} {RNA815_16128}
32. MligTC455_21721 1177 24.51 Mlig455_052943, Mlig455_053013

Neo: -

Age: -

TRPM3 0.951 - - - - - 0.951

Mlig455_052943 {REF} {Length: 4423} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.0]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=52.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=521, Expect=2e-158]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=522, Expect=1e-158]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=484, Expect=1e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=362, Expect=8e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=607, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}

Mlig455_053013 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.1]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=53.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=8e-157]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=519, Expect=2e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=8e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=605, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1, RNA1509_4847} {RNA1509_4847, RNA815_652.1}
33. MligTC455_23599 300 6.25 Mlig455_025579

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.645/0.00082

FBN2 0.951 - - - - - 0.951 Mlig455_025579 {REF} {Length: 10696} {Pfam: Calcium-binding EGF domain [PF07645.17, score=312.2]; Complement Clr-like EGF-like [PF12662.9, score=241.1]; Coagulation Factor Xa inhibitory site [PF14670.8, score=125.1]; EGF domain [PF12947.9, score=95.9]; EGF-like domain [PF00008.29, score=59.7]; Human growth factor-like EGF [PF12661.9, score=47.9]; Thrombospondin type 1 domain [PF00090.21, score=28.9]; MSP1 EGF domain 1 [PF12946.9, score=21.3]} {Human: ENSG00000138829, FBN2, fibrillin 2, [Score=250, Expect=2e-65]; ENSG00000166147, FBN1, fibrillin 1, [Score=248, Expect=1e-64]; ENSG00000142449, FBN3, fibrillin 3, [Score=243, Expect=3e-63]} {Mouse: ENSMUSG00000024598, Fbn2, fibrillin 2, [Score=253, Expect=1e-66]; ENSMUSG00000027204, Fbn1, fibrillin 1, [Score=251, Expect=5e-66]} {Dmel: FBgn0035798, frac, faulty attraction, [RH, Score=238, Expect=3e-62]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=192, Expect=3e-50]} {Smed: dd_Smed_v6_2649_0_2, dd_Smed_v6_2649_0_2, [Score=294, Expect=3e-79]} {RNA1509_13106} {RNA1310_487} {RNA815_5734}
34. MligTC455_23818 346 7.22 Mlig455_017619

Neo: -

Age: Up-Down-Down

MEGF8 0.951 - - - - - 0.951 Mlig455_017619 {REF} {Length: 10161} {TRANSSPLICED} {Pfam: Kelch motif [PF13854.8, score=47.9]; Laminin EGF domain [PF00053.26, score=36.6]; EGF domain [PF12947.9, score=34.7]; Galactose oxidase, central domain [PF13418.8, score=30.1]; Calcium-binding EGF domain [PF07645.17, score=27.0]; Human growth factor-like EGF [PF12661.9, score=26.6]; EGF-like domain [PF00008.29, score=23.8]; Plexin repeat [PF01437.27, score=19.2]} {Human: ENSG00000105429, MEGF8, multiple EGF like domains 8, [Score=508, Expect=3e-146]} {Mouse: ENSMUSG00000045039, Megf8, multiple EGF-like-domains 8, [Score=538, Expect=5e-156]} {Dmel: FBgn0031981, CG7466, [Score=504, Expect=6e-145]} {Celegans: WBGene00006787, unc-52, Basement membrane proteoglycan, [Score=68.2, Expect=7e-11]} {Smed: dd_Smed_v6_9737_0_1, dd_Smed_v6_9737_0_1, [Score=61.6, Expect=3e-09]} {RNA1509_3629, RNA1509_53359} {RNA1310_138.1, RNA1509_53359} {RNA1509_53359, RNA815_1847.1}
35. MligTC455_28110 114 2.37 Mlig455_023739, Mlig455_051660, Mlig455_063344

Neo: -

Age: -

0.951 - - - - - 0.951

Mlig455_023739 {REF} {Length: 896} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_14078} {RNA815_15623}

Mlig455_051660 {REF} {Length: 1105} {NoTransDecoderORF} {RNA1509_32637} {RNA1310_15891} {RNA815_15623}

Mlig455_063344 {REF} {Length: 896} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_14078} {RNA815_15623}
36. MligTC455_23105 85 1.77 Mlig455_066252

Neo: -

Age: -

Region-enriched R2: 4.557/0.00175

0.95 - - - - - 0.950 Mlig455_066252 {REF} {Length: 1850} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF3504) [PF12012.10, score=29.4]} {RNA1509_53869} {RNA1310_20011} {RNA815_7057.1}
37. MligTC455_45052 26 0.54 Mlig455_047471

Neo: -

Age: Up-Down-Up

0.95 - - - - - 0.950 Mlig455_047471 {REF} {Length: 3750} {TRANSSPLICED} {RNA1310_38765} {RNA815_44260}

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