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Results for MligTC455_39665

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_39665 112 2.33 Mlig455_023730

Neo: -

Age: -

EPHA7 Mlig455_023730 {REF} {Length: 3591} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.8]; Protein kinase domain [PF00069.27, score=130.1]; Ephrin receptor ligand binding domain [PF01404.21, score=107.2]; Fibronectin type III domain [PF00041.23, score=95.6]; Ephrin type-A receptor 2 transmembrane domain [PF14575.8, score=57.6]; SAM domain (Sterile alpha motif) [PF07647.19, score=55.1]; SAM domain (Sterile alpha motif) [PF00536.32, score=50.6]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.9]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=19.2]} {Human: ENSG00000135333, EPHA7, EPH receptor A7, [Score=658, Expect=0.0]; ENSG00000145242, EPHA5, EPH receptor A5, [Score=647, Expect=0.0]; ENSG00000116106, EPHA4, EPH receptor A4, [Score=646, Expect=0.0]} {Mouse: ENSMUSG00000028289, Epha7, Eph receptor A7, [Score=659, Expect=0.0]; ENSMUSG00000026235, Epha4, Eph receptor A4, [Score=651, Expect=0.0]; ENSMUSG00000029245, Epha5, Eph receptor A5, [Score=648, Expect=0.0]} {Dmel: FBgn0025936, Eph, Eph receptor tyrosine kinase, [Score=609, Expect=0.0]} {Celegans: WBGene00006868, vab-1, Ephrin receptor 1, [Score=458, Expect=2e-143]} {Smed: dd_Smed_v6_16928_0_1, dd_Smed_v6_16928_0_1, [Score=552, Expect=7e-180]} {RNA1509_24016} {RNA1310_2298.1} {RNA815_19987}

Cumulative graph for MligTC455_39665

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.263 2.046 0.90601 1.00000
RegionR2 0.518 2.046 0.53394 0.90453
RegionR3 -1.119 2.046 0.12635 0.61217
RegionR4 0.543 2.046 0.49374 0.82038
RegionR5 -0.55 2.046 0.38704 0.74259
RegionR6 -0.388 2.046 0.58031 1.00000
RegionR7 0.801 2.046 0.32708 0.96152
RegionR8 -0.068 2.046 0.94720 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -4.374 2.046 0.48691 1.00000
RegenerationR2 0.491 2.046 0.36468 0.79178
RegenerationR3 0.806 2.046 0.30654 0.73739
RegenerationR4 -1.251 2.046 0.11104 0.51141
RegenerationR5 -0.542 2.046 0.43658 0.82242
RegenerationR6 -0.808 2.046 0.36393 0.70786
RegenerationBL -4.871 2.046 0.03380 0.20620
RegenerationTP -0.991 2.046 0.37486 0.81143


Genes with expression patterns similar to MligTC455_39665

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_39665 112 2.33 Mlig455_023730

Neo: -

Age: -

EPHA7 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_023730 {REF} {Length: 3591} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.8]; Protein kinase domain [PF00069.27, score=130.1]; Ephrin receptor ligand binding domain [PF01404.21, score=107.2]; Fibronectin type III domain [PF00041.23, score=95.6]; Ephrin type-A receptor 2 transmembrane domain [PF14575.8, score=57.6]; SAM domain (Sterile alpha motif) [PF07647.19, score=55.1]; SAM domain (Sterile alpha motif) [PF00536.32, score=50.6]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.9]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=19.2]} {Human: ENSG00000135333, EPHA7, EPH receptor A7, [Score=658, Expect=0.0]; ENSG00000145242, EPHA5, EPH receptor A5, [Score=647, Expect=0.0]; ENSG00000116106, EPHA4, EPH receptor A4, [Score=646, Expect=0.0]} {Mouse: ENSMUSG00000028289, Epha7, Eph receptor A7, [Score=659, Expect=0.0]; ENSMUSG00000026235, Epha4, Eph receptor A4, [Score=651, Expect=0.0]; ENSMUSG00000029245, Epha5, Eph receptor A5, [Score=648, Expect=0.0]} {Dmel: FBgn0025936, Eph, Eph receptor tyrosine kinase, [Score=609, Expect=0.0]} {Celegans: WBGene00006868, vab-1, Ephrin receptor 1, [Score=458, Expect=2e-143]} {Smed: dd_Smed_v6_16928_0_1, dd_Smed_v6_16928_0_1, [Score=552, Expect=7e-180]} {RNA1509_24016} {RNA1310_2298.1} {RNA815_19987}
2. MligTC455_39664 122 2.55 Mlig455_023719, Mlig455_023723

Neo: -

Age: -

EPHA2, EPHA7 5.808 0.990 0.984 0.986 0.939 0.919 0.990

Mlig455_023719 {REF} {Length: 1150} {TRANSSPLICED} {Pfam: Ephrin receptor ligand binding domain [PF01404.21, score=109.7]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=25.3]; Giardia variant-specific surface protein [PF03302.15, score=17.7]} {Human: ENSG00000142627, EPHA2, EPH receptor A2, [Score=164, Expect=4e-44]} {Mouse: ENSMUSG00000006445, Epha2, Eph receptor A2, [Score=159, Expect=3e-42]} {Celegans: WBGene00006868, vab-1, Ephrin receptor 1, [Score=86.7, Expect=4e-18]} {Smed: dd_Smed_v6_16928_0_1, dd_Smed_v6_16928_0_1, [Score=155, Expect=2e-41]} {RNA1509_51951} {RNA1310_2298.1} {RNA815_18224.1}

Mlig455_023723 {REF} {Length: 5114} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=285.8]; Protein kinase domain [PF00069.27, score=130.1]; Ephrin receptor ligand binding domain [PF01404.21, score=107.2]; Fibronectin type III domain [PF00041.23, score=95.6]; Ephrin type-A receptor 2 transmembrane domain [PF14575.8, score=57.6]; SAM domain (Sterile alpha motif) [PF07647.19, score=55.1]; SAM domain (Sterile alpha motif) [PF00536.32, score=50.6]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.9]; Tyrosine-protein kinase ephrin type A/B receptor-like [PF07699.15, score=19.2]} {Human: ENSG00000135333, EPHA7, EPH receptor A7, [Score=658, Expect=0.0]; ENSG00000145242, EPHA5, EPH receptor A5, [Score=647, Expect=0.0]; ENSG00000116106, EPHA4, EPH receptor A4, [Score=646, Expect=0.0]} {Mouse: ENSMUSG00000028289, Epha7, Eph receptor A7, [Score=659, Expect=0.0]; ENSMUSG00000026235, Epha4, Eph receptor A4, [Score=651, Expect=0.0]; ENSMUSG00000029245, Epha5, Eph receptor A5, [Score=648, Expect=0.0]} {Dmel: FBgn0025936, Eph, Eph receptor tyrosine kinase, [Score=609, Expect=0.0]} {Celegans: WBGene00006868, vab-1, Ephrin receptor 1, [Score=458, Expect=2e-143]} {Smed: dd_Smed_v6_16928_0_1, dd_Smed_v6_16928_0_1, [Score=552, Expect=7e-180]} {RNA1509_24016} {RNA1310_2298.1} {RNA815_10575}
3. MligTC455_02758 129 2.69 Mlig455_001648, Mlig455_001715

Neo: -

Age: logFC(26M/2M)=-0.349

2.604 - - 0.973 0.727 - 0.904

Mlig455_001648 {REF} {Length: 2010} {Pfam: Death domain [PF00531.24, score=20.4]} {RNA1509_32212, RNA1509_57415} {RNA1310_29260, RNA1509_32212, RNA1509_57415} {RNA1509_32212, RNA1509_57415, RNA815_17490}

Mlig455_001715 {REF} {Length: 1221} {RNA1509_32212} {RNA1310_56586} {RNA815_40737.1}
4. MligTC455_24302 149 3.11 Mlig455_035632

Neo: -

Age: Up-Down-Up

KCNQ5 2.381 0.701 - - 0.730 - 0.950 Mlig455_035632 {REF} {Length: 2263} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=124.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [Score=122, Expect=1e-28]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [Score=121, Expect=2e-28]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [Score=121, Expect=1e-28]; ENSMUSG00000028631, Kcnq4, potassium voltage-gated channel, subfamily Q, member 4, [Score=119, Expect=4e-28]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [Score=175, Expect=1e-46]} {Celegans: WBGene00002235, kqt-3, KQT-3 potassium channel; Potassium channel, KvQLT family, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_17359_0_2, dd_Smed_v6_17359_0_2, [Score=186, Expect=2e-52]} {RNA1509_34272} {RNA1310_3730.1} {RNA815_2787}
5. MligTC455_24614 62 1.29 Mlig455_015091, Mlig455_015206

Neo: -

Age: logFC(26M/2M)=-0.441

Region-enriched R4: 7.131/0.00032

Regeneration-downregulated R4: -4.923

Regeneration-depleted R4: -4.923

ECT2 1.914 - - - 0.974 - 0.940

Mlig455_015091 {REF} {Length: 3092} {Pfam: RhoGEF domain [PF00621.22, score=124.1]; Domain of unknown function (DUF4795) [PF16043.7, score=21.0]; Winged helix-turn helix [PF13592.8, score=19.5]} {Human: ENSG00000114346, ECT2, epithelial cell transforming 2, [Score=78.6, Expect=2e-14]} {Mouse: ENSMUSG00000020640, Itsn2, intersectin 2, [Score=78.6, Expect=2e-14]; ENSMUSG00000027699, Ect2, ect2 oncogene, [Score=74.7, Expect=2e-13]} {Dmel: FBgn0003041, pbl, pebble, [Score=57.0, Expect=6e-08]} {Celegans: WBGene00002297, ect-2, ECT2 (Mammalian Rho GEF) homolog, [Score=67.0, Expect=3e-11]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=59.7, Expect=5e-09]} {RNA1509_21158} {RNA1310_6370} {RNA815_1845}

Mlig455_015206 {REF} {Length: 3091} {Pfam: RhoGEF domain [PF00621.22, score=124.1]; Domain of unknown function (DUF4795) [PF16043.7, score=21.0]; Winged helix-turn helix [PF13592.8, score=19.5]} {Human: ENSG00000114346, ECT2, epithelial cell transforming 2, [Score=78.6, Expect=2e-14]} {Mouse: ENSMUSG00000020640, Itsn2, intersectin 2, [Score=78.6, Expect=2e-14]; ENSMUSG00000027699, Ect2, ect2 oncogene, [Score=74.7, Expect=2e-13]} {Dmel: FBgn0003041, pbl, pebble, [Score=57.0, Expect=6e-08]} {Celegans: WBGene00002297, ect-2, ECT2 (Mammalian Rho GEF) homolog, [Score=67.0, Expect=3e-11]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=59.7, Expect=5e-09]} {RNA1509_21158, RNA1509_7033} {RNA1310_6370, RNA1509_21158, RNA1509_7033} {RNA1509_21158, RNA1509_7033, RNA815_1845}
6. MligTC455_45021 381 7.95 Mlig455_046686

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.428/0.03156

AVP 1.902 - - - 0.952 - 0.950 Mlig455_046686 {REF} {Length: 1388} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.2]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=54.3, Expect=2e-09]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=53.1, Expect=3e-09]} {RNA1509_50574} {RNA1310_38922} {RNA815_23813}
7. MligTC455_19716 35 0.73 Mlig455_008148

Neo: -

Age: -

NPY1R 1.901 - - - 0.942 - 0.959 Mlig455_008148 {REF} {Length: 3212} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=183.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=46.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=36.4]} {Human: ENSG00000164128, NPY1R, neuropeptide Y receptor Y1, [RH, Score=167, Expect=8e-47]} {Mouse: ENSMUSG00000031932, Gpr83, G protein-coupled receptor 83, [RH, Score=170, Expect=8e-48]; ENSMUSG00000036437, Npy1r, neuropeptide Y receptor Y1, [RH, Score=167, Expect=7e-47]} {Dmel: FBgn0036934, sNPF-R, short neuropeptide F receptor, [RH, Score=256, Expect=1e-78]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [RH, Score=220, Expect=3e-67]} {Smed: dd_Smed_v6_10020_0_1, dd_Smed_v6_10020_0_1, [RH, Score=336, Expect=1e-112]} {RNA1310_21371} {RNA815_7986}
8. MligTC455_49825 543 11.31 Mlig455_069114

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.806

Region-enriched R2: 3.936/0.00000

1.898 - - - 0.933 - 0.965 Mlig455_069114 {REF} {Length: 828} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=40.0, Expect=9e-06]} {RNA1509_26665} {RNA1310_48731, RNA1509_26665} {RNA1509_26665, RNA815_24488}
9. MligTC455_14176 30 0.63 Mlig455_058283

Neo: -

Age: -

1.897 - - 0.959 0.938 - - Mlig455_058283 {REF} {Length: 1230} {NoTransDecoderORF} {RNA1509_16231} {RNA1310_87164} {RNA815_8904.1}
10. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

1.893 - - - 0.937 - 0.956 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
11. MligTC455_18333 273 5.7 Mlig455_010935

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.059/0.00307

1.89 - - - 0.928 - 0.962 Mlig455_010935 {REF} {Length: 510} {RNA1310_33328.2} {RNA815_15093.1}
12. MligTC455_49824 466 9.71 Mlig455_036536

Neo: -

Age: -

Region-specific R2: 4.841

Region-enriched R2: 3.862/0.00010

1.89 - - - 0.934 - 0.956 Mlig455_036536 {REF} {Length: 1139} {Pfam: Nucleoporin FG repeat region [PF13634.8, score=21.2]} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [RH, Score=49.3, Expect=7e-08]} {RNA1509_18714, RNA1509_59524} {RNA1310_41906, RNA1509_18714, RNA1509_59524} {RNA1509_18714, RNA1509_59524, RNA815_24488}
13. MligTC455_43173 392 8.16 Mlig455_037383

Neo: -

Age: Up-Down-Down

Regeneration-downregulated TP: -5.031

Regeneration-depleted TP: -5.031

C2orf16 1.887 - - - 0.935 - 0.952 Mlig455_037383 {REF} {Length: 2450} {Pfam: Cornifin (SPRR) family [PF02389.17, score=23.4]} {Human: ENSG00000221843, C2orf16, chromosome 2 open reading frame 16, [Score=80.1, Expect=7e-15]} {RNA1509_52401} {RNA1310_14622.1} {RNA815_17994}
14. MligTC455_42520 221 4.6 Mlig455_051277

Neo: -

Age: Down-Up-Up

Region-specific R2: 7.331

Region-enriched R2: 7.171/0.00000

Regeneration-downregulated R2: -3.384

Regeneration-depleted R2: -3.384

1.881 - - - 0.931 - 0.950 Mlig455_051277 {REF} {Length: 969} {RNA1310_42329} {RNA815_20649}
15. MligTC455_34525 52 1.08 Mlig455_021566

Neo: -

Age: Down-Up-Down

GNAI1 1.878 - - - 0.954 - 0.924 Mlig455_021566 {REF} {Length: 3532} {Pfam: G-protein alpha subunit [PF00503.22, score=404.9]; ADP-ribosylation factor family [PF00025.23, score=56.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=20.1]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.4]} {Human: ENSG00000127955, GNAI1, G protein subunit alpha i1, [Score=486, Expect=2e-171]; ENSG00000114353, GNAI2, G protein subunit alpha i2, [Score=481, Expect=3e-169]; ENSG00000065135, GNAI3, G protein subunit alpha i3, [Score=474, Expect=1e-166]} {Mouse: ENSMUSG00000057614, Gnai1, guanine nucleotide binding protein (G protein), alpha inhibiting 1, [Score=486, Expect=2e-171]; ENSMUSG00000032562, Gnai2, guanine nucleotide binding protein (G protein), alpha inhibiting 2, [Score=475, Expect=5e-167]; ENSMUSG00000000001, Gnai3, guanine nucleotide binding protein (G protein), alpha inhibiting 3, [Score=474, Expect=1e-166]} {Dmel: FBgn0001104, Galphai, G protein alpha i subunit, [Score=468, Expect=2e-164]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [Score=446, Expect=5e-156]} {Smed: dd_Smed_v6_12112_0_1, dd_Smed_v6_12112_0_1, [RH, Score=598, Expect=0.0]} {RNA1509_45426} {RNA1310_26920, RNA1509_45426} {RNA1509_45426, RNA815_11718}
16. MligTC455_50440 23 0.47 Mlig455_061066

Neo: -

Age: -

1.867 - - - 0.950 - 0.917 Mlig455_061066 {REF} {Length: 3956} {NoTransDecoderORF} {RNA1310_92899} {RNA815_52783}
17. MligTC455_24272 197 4.1 Mlig455_005121, Mlig455_005189

Neo: -

Age: Down-Up-Down

CHRNA7 1.854 - - - 0.970 - 0.884

Mlig455_005121 {REF} {Length: 1737} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=104.4]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=68.3]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=135, Expect=4e-34]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=134, Expect=3e-34]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=134, Expect=3e-34]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=131, Expect=3e-33]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=127, Expect=5e-32]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=119, Expect=6e-29]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=129, Expect=1e-32]} {Smed: dd_Smed_v6_12182_0_1, dd_Smed_v6_12182_0_1, [Score=120, Expect=2e-29]} {RNA1509_43533} {RNA1310_19997.1, RNA1509_43533} {RNA1509_43533, RNA815_7971}

Mlig455_005189 {REF} {Length: 1477} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=101.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=68.4]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=136, Expect=2e-34]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=136, Expect=1e-34]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=136, Expect=2e-34]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=133, Expect=8e-34]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=128, Expect=4e-32]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=117, Expect=4e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=130, Expect=1e-32]} {Smed: dd_Smed_v6_12182_0_1, dd_Smed_v6_12182_0_1, [Score=117, Expect=3e-28]} {RNA1509_43533} {RNA1310_19997.1} {RNA815_7971}
18. MligTC455_44328 858 17.88 Mlig455_026172

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.714

Region-enriched R2: 4.385/0.00000

1.853 - - - 0.903 - 0.950 Mlig455_026172 {REF} {Length: 661} {RNA1509_32102, RNA1509_34635} {RNA1310_60068, RNA1509_32102, RNA1509_34635} {RNA1509_32102, RNA1509_34635, RNA815_37486}
19. MligTC455_12183 53 1.11 Mlig455_004166, Mlig455_004190

Neo: -

Age: -

Region-enriched R2: 4.930/0.01881

1.844 - - - 0.950 - 0.894

Mlig455_004166 {REF} {Length: 2818} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=57.4]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=29.1]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=55.5, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=8e-12]} {RNA1310_64973} {RNA815_58453}

Mlig455_004190 {REF} {Length: 2742} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.7]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=28.6]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=56.2, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=1e-11]} {RNA1310_62602} {RNA815_58453}
20. MligTC455_19583 95 1.97 Mlig455_010583, Mlig455_010602

Neo: -

Age: -

Region-enriched R2: 6.442/0.00383

1.828 - - - 0.955 - 0.873

Mlig455_010583 {REF} {Length: 2325} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=173.5]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [Score=320, Expect=4e-101]} {RNA1310_36131} {RNA815_32135}

Mlig455_010602 {REF} {Length: 2432} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=182.9]} {Smed: dd_Smed_v6_15099_0_1, dd_Smed_v6_15099_0_1, [RH, Score=346, Expect=2e-110]} {RNA1310_36131} {RNA815_32135}
21. MligTC455_44340 133 2.77 Mlig455_046547

Neo: -

Age: Up-Down-Down

GPR158 1.814 - - - 0.973 - 0.841 Mlig455_046547 {REF} {Length: 3465} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=94.2]} {Human: ENSG00000151025, GPR158, G protein-coupled receptor 158, [RH, Score=246, Expect=8e-68]; ENSG00000276469, GPR179, G protein-coupled receptor 179, [RH, Score=240, Expect=3e-65]; ENSG00000277399, GPR179, G protein-coupled receptor 179, [RH, Score=234, Expect=3e-63]} {Mouse: ENSMUSG00000070337, Gpr179, G protein-coupled receptor 179, [RH, Score=253, Expect=7e-70]; ENSMUSG00000045967, Gpr158, G protein-coupled receptor 158, [RH, Score=251, Expect=1e-69]} {Dmel: FBgn0051660, smog, [RH, Score=285, Expect=1e-82]} {Celegans: WBGene00009558, F39B2.8, [Score=195, Expect=3e-53]} {Smed: dd_Smed_v6_8408_0_1, dd_Smed_v6_8408_0_1, [RH, Score=356, Expect=2e-111]} {RNA1509_37699} {RNA1310_6430, RNA1509_37699} {RNA1509_37699, RNA815_19661}
22. MligTC455_51764 938 19.55 Mlig455_016061

Neo: -

Age: -

Region-specific R2: 2.881

Region-enriched R2: 1.672/0.00180

1.814 - - - 0.841 - 0.973 Mlig455_016061 {REF} {Length: 649} {RNA1509_58232} {RNA1310_60107.1, RNA1509_58232} {RNA1509_58232, RNA815_31573}
23. MligTC455_24759 293 6.11 Mlig455_032990

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.793

PFN4 1.808 - - - - 0.968 0.840 Mlig455_032990 {REF} {Length: 1358} {Pfam: Profilin [PF00235.21, score=102.2]} {Human: ENSG00000176732, PFN4, profilin family member 4, [RH, Score=99.4, Expect=3e-27]} {Mouse: ENSMUSG00000020639, Pfn4, profilin family, member 4, [RH, Score=95.9, Expect=4e-26]} {Smed: dd_Smed_v6_2107_0_1, dd_Smed_v6_2107_0_1, [RH, Score=109, Expect=1e-31]} {RNA1509_34639} {RNA1310_16901.2, RNA1509_34639} {RNA1509_34639, RNA815_34827}
24. MligTC455_35373 50 1.03 Mlig455_065912, Mlig455_070019

Neo: -

Age: Down-Up-Down

Regeneration-upregulated BL: 7.651

Regeneration-enriched BL: 7.651

GLRA2 1.805 - - - 0.967 - 0.838

Mlig455_065912 {REF} {Length: 3290} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=157.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=121.2]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=327, Expect=1e-106]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=321, Expect=2e-104]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=319, Expect=1e-103]} {Mouse: ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=325, Expect=4e-106]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=323, Expect=3e-105]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=317, Expect=3e-103]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=313, Expect=2e-101]} {Dmel: FBgn0024963, GluClalpha, [Score=291, Expect=5e-93]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [RH, Score=249, Expect=2e-76]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=283, Expect=3e-90]} {RNA1509_32923} {RNA1310_14629.1} {RNA815_27491}

Mlig455_070019 {REF} {Length: 4890} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=157.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=120.3]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=326, Expect=2e-106]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=323, Expect=4e-105]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=318, Expect=2e-103]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=325, Expect=5e-106]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=324, Expect=7e-106]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=317, Expect=6e-103]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=313, Expect=1e-101]} {Dmel: FBgn0024963, GluClalpha, [Score=288, Expect=7e-92]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [RH, Score=249, Expect=2e-76]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=284, Expect=2e-90]} {RNA1509_32923} {RNA1310_14629.1} {RNA815_27491}
25. MligTC455_50661 79 1.64 Mlig455_059106

Neo: -

Age: -

1.793 - - - 0.836 - 0.957 Mlig455_059106 {REF} {Length: 711} {NoTransDecoderORF} {RNA1310_39553.1} {RNA815_32589}
26. MligTC455_25112 611 12.74 Mlig455_020700

Neo: -

Age: Down-Down-Up

Region-enriched R7: 1.981/0.01296

1.792 - - - 0.961 - 0.831 Mlig455_020700 {REF} {Length: 831} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=46.6, Expect=8e-07]} {RNA1509_27832, RNA1509_36958} {RNA1310_50245, RNA1509_27832, RNA1509_36958} {RNA1509_27832, RNA1509_36958, RNA815_48543}
27. MligTC455_35732 33 0.68 Mlig455_068717

Neo: -

Age: -

WSCD2 1.789 - - 0.833 0.956 - - Mlig455_068717 {REF} {Length: 1118} {Pfam: WSC domain [PF01822.21, score=44.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=53.9, Expect=4e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=49.7, Expect=8e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=57.8, Expect=1e-09]} {RNA1310_109959}
28. MligTC455_34748 1896 39.5 Mlig455_028992

Neo: -

Age: logFC(26M/2M)=1.173

Regeneration-downregulated BL: -3.995

Regeneration-depleted BL: -3.995

ELK1 1.785 - - - - 0.820 0.965 Mlig455_028992 {REF} {Length: 2125} {Pfam: Ets-domain [PF00178.24, score=59.1]} {Human: ENSG00000126767, ELK1, ELK1, ETS transcription factor, [Score=52.0, Expect=1e-06]; ENSG00000120690, ELF1, E74 like ETS transcription factor 1, [Score=51.6, Expect=2e-06]; ENSG00000124664, SPDEF, SAM pointed domain containing ETS transcription factor, [Score=51.2, Expect=2e-06]; ENSG00000134954, ETS1, ETS proto-oncogene 1, transcription factor, [Score=50.4, Expect=4e-06]; ENSG00000157557, ETS2, ETS proto-oncogene 2, transcription factor, [Score=50.1, Expect=6e-06]} {Mouse: ENSMUSG00000009406, Elk1, ELK1, member of ETS oncogene family, [Score=52.8, Expect=4e-07]; ENSMUSG00000036461, Elf1, E74-like factor 1, [Score=51.2, Expect=2e-06]; ENSMUSG00000024215, Spdef, SAM pointed domain containing ets transcription factor, [Score=50.4, Expect=2e-06]; ENSMUSG00000032035, Ets1, E26 avian leukemia oncogene 1, 5' domain, [Score=50.4, Expect=3e-06]} {Dmel: FBgn0000567, Eip74EF, Ecdysone-induced protein 74EF, [Score=51.2, Expect=1e-06]} {Celegans: WBGene00016029, elf-1, See eff, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_7247_0_1, dd_Smed_v6_7247_0_1, [RH, Score=70.5, Expect=2e-13]} {RNA1509_11103, RNA1509_23008, RNA1509_2890, RNA1509_7878} {RNA1310_14259.1, RNA1509_11103, RNA1509_23008, RNA1509_2890, RNA1509_7878} {RNA1509_11103, RNA1509_23008, RNA1509_2890, RNA1509_7878, RNA815_2480.2}
29. MligTC455_44133 351 7.31 Mlig455_025463

Neo: -

Age: -

C20orf85 1.779 - - - - 0.810 0.969 Mlig455_025463 {REF} {Length: 939} {TRANSSPLICED} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=99.7]} {Human: ENSG00000124237, C20orf85, chromosome 20 open reading frame 85, [Score=57.0, Expect=1e-10]} {Mouse: ENSMUSG00000027518, 1700021F07Rik, RIKEN cDNA 1700021F07 gene, [Score=64.7, Expect=8e-14]} {Smed: dd_Smed_v6_2729_0_1, dd_Smed_v6_2729_0_1, [Score=102, Expect=6e-29]} {RNA1509_43017} {RNA1310_30520.1} {RNA815_25802}
30. MligTC455_32366 22 0.45 Mlig455_034995, Mlig455_056739

Neo: -

Age: -

KREMEN2 1.774 - - - - 0.814 0.960

Mlig455_034995 {REF} {Length: 838} {Pfam: WSC domain [PF01822.21, score=57.3]; PAN domain [PF00024.28, score=30.2]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=48.9, Expect=2e-06]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=53.1, Expect=7e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=64.7, Expect=6e-12]} {RNA1310_90615} {RNA815_32019}

Mlig455_056739 {REF} {Length: 3691} {RNA1310_90615} {RNA815_24291.1}
31. MligTC455_22150 189 3.94 Mlig455_054947

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.071

XDH 1.773 - - 0.820 - - 0.953 Mlig455_054947 {REF} {Length: 5481} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=346.4]; [2Fe-2S] binding domain [PF01799.22, score=95.7]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=91.5]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=51.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=47.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=25.1]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=476, Expect=9e-146]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=471, Expect=4e-144]; ENSMUSG00000079554, Aox2, aldehyde oxidase 2, [Score=457, Expect=7e-139]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=456, Expect=1e-138]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=449, Expect=5e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=640, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=485, Expect=1e-149]} {RNA1509_325, RNA1509_38160} {RNA1310_1603.1, RNA1509_38160} {RNA1509_38160, RNA815_224.2}
32. MligTC455_32428 352 7.33 Mlig455_013946

Neo: -

Age: -

NWD2 1.765 - - 0.803 - - 0.962 Mlig455_013946 {REF} {Length: 7112} {TRANSSPLICED} {Pfam: NACHT domain [PF05729.14, score=45.6]; AAA ATPase domain [PF13191.8, score=41.4]; Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA domain [PF13401.8, score=24.5]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=431, Expect=4e-131]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=426, Expect=2e-129]} {Dmel: FBgn0038397, CG10185, [Score=520, Expect=4e-164]} {Celegans: WBGene00020254, T05C3.2, [Score=530, Expect=2e-167]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=323, Expect=7e-94]} {RNA1509_3054} {RNA1310_322} {RNA815_139.1}
33. MligTC455_33622 44 0.92 Mlig455_053946, Mlig455_060582

Neo: -

Age: Up-Down-Down

MTNR1B 1.755 - - - 0.951 0.804 -

Mlig455_053946 {REF} {Length: 3240} {TRANSSPLICED} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=156.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=33.1]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.1]} {Human: ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=136, Expect=4e-36]; ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=130, Expect=2e-32]} {Mouse: ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=126, Expect=1e-32]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=123, Expect=3e-30]; ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=122, Expect=5e-31]} {Dmel: FBgn0025631, moody, [Score=105, Expect=2e-24]} {Celegans: WBGene00001052, dop-1, DOPamine receptor, [Score=96.7, Expect=8e-22]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=203, Expect=2e-62]} {RNA1509_18800} {RNA1310_23658} {RNA815_33287}

Mlig455_060582 {REF} {Length: 3239} {TRANSSPLICED} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=156.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=33.1]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.1]} {Human: ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=136, Expect=4e-36]; ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=130, Expect=2e-32]} {Mouse: ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=126, Expect=1e-32]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=123, Expect=3e-30]; ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=122, Expect=5e-31]} {Dmel: FBgn0025631, moody, [Score=105, Expect=2e-24]} {Celegans: WBGene00001052, dop-1, DOPamine receptor, [Score=96.7, Expect=8e-22]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=203, Expect=2e-62]} {RNA1509_18800} {RNA1310_23658} {RNA815_33287}
34. MligTC455_36078 21 0.44 Mlig455_032513

Neo: -

Age: -

1.755 - - 0.800 - - 0.955 Mlig455_032513 {REF} {Length: 503} {NoTransDecoderORF} {RNA1509_45539} {RNA1310_77014} {RNA815_40738}
35. MligTC455_40468 380 7.91 Mlig455_023112

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.379

LRRC72 1.742 - - - - 0.789 0.953 Mlig455_023112 {REF} {Length: 1305} {Pfam: Leucine-rich repeat [PF14580.8, score=70.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.2]; Leucine rich repeat [PF13855.8, score=23.3]} {Human: ENSG00000205858, LRRC72, leucine rich repeat containing 72, [RH, Score=130, Expect=7e-36]} {Mouse: ENSMUSG00000020545, Lrrc72, leucine rich repeat containing 72, [RH, Score=140, Expect=2e-39]} {Dmel: FBgn0014395, tilB, touch insensitive larva B, [Score=50.4, Expect=8e-07]} {Celegans: WBGene00003390, mog-2, Probable U2 small nuclear ribonucleoprotein A', [Score=73.2, Expect=5e-15]} {Smed: dd_Smed_v6_5405_0_1, dd_Smed_v6_5405_0_1, [Score=60.5, Expect=1e-10]} {RNA1509_41640, RNA1509_50261} {RNA1310_32093.1, RNA1509_41640, RNA1509_50261} {RNA1509_41640, RNA1509_50261, RNA815_12512}
36. MligTC455_17586 579 12.07 Mlig455_029070

Neo: -

Age: -

Region-specific R2: 3.959

Region-enriched R2: 2.423/0.00859

Regeneration-downregulated R6: -3.050

Regeneration-depleted R6: -3.050

1.739 - - - 0.951 - 0.788 Mlig455_029070 {REF} {Length: 859} {RNA1509_53221, RNA1509_56226} {RNA1310_52775.1, RNA1509_53221, RNA1509_56226} {RNA1509_53221, RNA1509_56226, RNA815_35656}
37. MligTC455_30730 121 2.52 Mlig455_010096

Neo: -

Age: Up-Down-Down

CACNA1H 1.729 0.744 - - - - 0.985 Mlig455_010096 {REF} {Length: 5627} {Pfam: Ion transport protein [PF00520.33, score=445.4]; Polycystin cation channel [PF08016.14, score=60.4]; Domain of unknown function (DUF4834) [PF16118.7, score=22.5]; FAM176 family [PF14851.8, score=20.1]} {Human: ENSG00000196557, CACNA1H, calcium voltage-gated channel subunit alpha1 H, [RH, Score=748, Expect=0.0]; ENSG00000100346, CACNA1I, calcium voltage-gated channel subunit alpha1 I, [RH, Score=734, Expect=0.0]} {Mouse: ENSMUSG00000024112, Cacna1h, calcium channel, voltage-dependent, T type, alpha 1H subunit, [Score=870, Expect=0.0]} {Dmel: FBgn0264386, Ca-alpha1T, Ca[2+]-channel protein alpha[[1]] subunit T, [RH, Score=868, Expect=0.0]} {Celegans: WBGene00000367, cca-1, Voltage-dependent T-type calcium channel subunit alpha, [RH, Score=774, Expect=0.0]} {Smed: dd_Smed_v6_14730_0_1, dd_Smed_v6_14730_0_1, [Score=1018, Expect=0.0]} {RNA1509_27261, RNA1509_28376} {RNA1310_7416.1, RNA1509_27261, RNA1509_28376} {RNA1509_27261, RNA1509_28376, RNA815_3853}
38. MligTC455_16964 15 0.31 Mlig455_038846

Neo: -

Age: -

1.728 - - 0.973 - 0.755 - Mlig455_038846 {REF} {Length: 598} {NoTransDecoderORF} {RNA1310_139317} {RNA815_31479}
39. MligTC455_13683 64 1.33 Mlig455_024287

Neo: -

Age: -

NDRG1 1.727 - - - 0.773 - 0.954 Mlig455_024287 {REF} {Length: 1644} {TRANSSPLICED} {Pfam: Ndr family [PF03096.16, score=199.1]} {Human: ENSG00000104419, NDRG1, N-myc downstream regulated 1, [RH, Score=136, Expect=5e-36]; ENSG00000101079, NDRG3, NDRG family member 3, [RH, Score=134, Expect=3e-35]; ENSG00000103034, NDRG4, NDRG family member 4, [RH, Score=133, Expect=2e-35]; ENSG00000165795, NDRG2, NDRG family member 2, [RH, Score=131, Expect=2e-34]} {Mouse: ENSMUSG00000027634, Ndrg3, N-myc downstream regulated gene 3, [RH, Score=131, Expect=1e-34]; ENSMUSG00000004558, Ndrg2, N-myc downstream regulated gene 2, [RH, Score=130, Expect=3e-34]; ENSMUSG00000005125, Ndrg1, N-myc downstream regulated gene 1, [RH, Score=130, Expect=7e-34]; ENSMUSG00000036564, Ndrg4, N-myc downstream regulated gene 4, [RH, Score=130, Expect=1e-34]} {Dmel: FBgn0043070, MESK2, Misexpression suppressor of KSR 2, [RH, Score=147, Expect=3e-40]} {Celegans: WBGene00014213, ZK1073.1, [RH, Score=128, Expect=5e-34]} {Smed: dd_Smed_v6_1911_0_1, dd_Smed_v6_1911_0_1, [RH, Score=243, Expect=2e-77]} {RNA1509_23780} {RNA1310_107043} {RNA815_11809.1}
40. MligTC455_09653 51 1.06 Mlig455_044944

Neo: -

Age: -

SLC17A6 1.725 - - - - 0.768 0.957 Mlig455_044944 {REF} {Length: 2769} {Pfam: Major Facilitator Superfamily [PF07690.18, score=118.9]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [Score=260, Expect=4e-79]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [Score=248, Expect=1e-74]} {Mouse: ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [Score=259, Expect=8e-79]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [Score=249, Expect=3e-75]; ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [Score=248, Expect=2e-74]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=223, Expect=1e-64]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [Score=203, Expect=2e-58]} {Smed: dd_Smed_v6_21295_0_1, dd_Smed_v6_21295_0_1, [RH, Score=616, Expect=0.0]} {RNA1310_79790} {RNA815_45443}
41. MligTC455_20294 341 7.11 Mlig455_007896, Mlig455_008003

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.032/0.04842

LRRK2 1.723 - - 0.771 - - 0.952

Mlig455_007896 {REF} {Length: 11344} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=164.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=71.6]; TIR domain [PF13676.8, score=57.4]; Leucine rich repeat [PF13855.8, score=43.0]; Ras family [PF00071.24, score=38.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.8]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=3e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=166, Expect=5e-40]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=7e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=125, Expect=4e-28]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=723, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1, RNA1509_8727} {RNA1509_8727, RNA815_1320}

Mlig455_008003 {REF} {Length: 11209} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=160.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.4]; TIR domain [PF13676.8, score=59.5]; Leucine rich repeat [PF13855.8, score=45.2]; Ras family [PF00071.24, score=39.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=28.4]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=1e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=163, Expect=1e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=4e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=120, Expect=1e-26]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=686, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1} {RNA815_1320}
42. MligTC455_25113 762 15.87 Mlig455_020768

Neo: -

Age: Down-Up-Down

Region-enriched R7: 2.653/0.00004
Region-enriched R2: 2.201/0.02449

1.722 - - - 0.952 - 0.770 Mlig455_020768 {REF} {Length: 810} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=46.2, Expect=1e-06]} {RNA1509_36958} {RNA1310_50245} {RNA815_48543}
43. MligTC455_15898 111 2.32 Mlig455_034780

Neo: -

Age: -

Region-enriched R2: 4.729/0.00758

STOM 1.721 - - - 0.959 - 0.762 Mlig455_034780 {REF} {Length: 2617} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=108.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=298, Expect=5e-99]; ENSG00000133115, STOML3, stomatin like 3, [Score=293, Expect=3e-97]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=294, Expect=6e-98]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=285, Expect=3e-94]} {Dmel: FBgn0260657, CG42540, [Score=308, Expect=1e-100]} {Celegans: WBGene00006064, sto-2, Stomatin-2, [Score=309, Expect=5e-103]} {Smed: dd_Smed_v6_6562_0_1, dd_Smed_v6_6562_0_1, [RH, Score=389, Expect=5e-134]} {RNA1509_39119} {RNA1310_7313, RNA1509_39119} {RNA1509_39119, RNA815_17831}
44. MligTC455_18713 134 2.79 Mlig455_057934, Mlig455_057969

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.845

1.718 - - - 0.756 - 0.962

Mlig455_057934 {REF} {Length: 1721} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=25.5]} {RNA1310_29499} {RNA815_28946}

Mlig455_057969 {REF} {Length: 1785} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=25.1]} {RNA1310_29499} {RNA815_28946}
45. MligTC455_34738 836 17.41 Mlig455_032157, Mlig455_032163, Mlig455_067631

Neo: -

Age: -

1.717 - - - - 0.746 0.971

Mlig455_032157 {REF} {Length: 1841} {Pfam: Stathmin family [PF00836.21, score=49.5]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [RH, Score=80.5, Expect=2e-21]} {RNA1509_18048, RNA1509_6791} {RNA1310_32272, RNA1509_18048, RNA1509_6791} {RNA1509_18048, RNA1509_6791, RNA815_831}

Mlig455_032163 {REF} {Length: 1001} {Pfam: Stathmin family [PF00836.21, score=44.6]} {Smed: dd_Smed_v6_512_0_1, dd_Smed_v6_512_0_1, [RH, Score=84.0, Expect=3e-22]} {RNA1509_6791} {RNA1310_71333} {RNA815_831}

Mlig455_067631 {REF} {Length: 817} {Pfam: Stathmin family [PF00836.21, score=31.3]} {RNA1509_6791} {RNA1310_71333} {RNA815_831}
46. MligTC455_40467 376 7.84 Mlig455_023012

Neo: -

Age: -

1.717 - - - - 0.762 0.955 Mlig455_023012 {REF} {Length: 944} {Celegans: WBGene00015646, mlt-10, [Score=150, Expect=4e-42]} {RNA1509_41640} {RNA1310_84380.1} {RNA815_12512}
47. MligTC455_49877 188 3.91 Mlig455_027465

Neo: -

Age: -

Region-enriched R2: 3.005/0.04141

AC254952.1 1.713 - - - 0.761 - 0.952 Mlig455_027465 {REF} {Length: 2059} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=89.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.0]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=6e-38]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=144, Expect=9e-38]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=141, Expect=2e-36]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=1e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=6e-37]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=139, Expect=5e-36]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=134, Expect=2e-34]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=132, Expect=4e-33]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=126, Expect=6e-32]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=131, Expect=2e-33]} {RNA1310_26175} {RNA815_7952}
48. MligTC455_43372 32 0.66 Mlig455_024808

Neo: -

Age: -

1.712 - - 0.760 - - 0.952 Mlig455_024808 {REF} {Length: 2553} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=28.5]; Prokaryotic RING finger family 4 [PF14447.8, score=25.4]} {RNA1310_52604} {RNA815_64021}
49. MligTC455_26943 239 4.97 Mlig455_016974, Mlig455_021256

Neo: -

Age: logFC(26M/2M)=-0.497

ANKRD29 1.708 - - - 0.753 - 0.955

Mlig455_016974 {REF} {Length: 1870} {RNA1509_19588} {RNA1310_63032} {RNA815_21121}

Mlig455_021256 {REF} {Length: 3308} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=111.7]; Ankyrin repeats (many copies) [PF13637.8, score=73.4]; Ankyrin repeat [PF00023.32, score=54.8]; Ankyrin repeats (many copies) [PF13857.8, score=48.7]; Ankyrin repeat [PF13606.8, score=41.8]; Mab-21 protein [PF03281.16, score=20.6]} {Human: ENSG00000154065, ANKRD29, ankyrin repeat domain 29, [Score=110, Expect=4e-26]} {Mouse: ENSMUSG00000057766, Ankrd29, ankyrin repeat domain 29, [Score=108, Expect=1e-25]} {Dmel: FBgn0031473, CG3104, [Score=104, Expect=3e-24]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=90.1, Expect=5e-18]} {Smed: dd_Smed_v6_9936_0_1, dd_Smed_v6_9936_0_1, [Score=119, Expect=7e-28]} {RNA1509_19588} {RNA1310_2850.1} {RNA815_6489}
50. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

1.701 - - - 0.746 - 0.955 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
51. MligTC455_49763 130 2.72 Mlig455_006404

Neo: -

Age: -

Region-enriched R2: 3.029/0.02346

KREMEN1 1.699 - - - - 0.731 0.968 Mlig455_006404 {REF} {Length: 1879} {Pfam: WSC domain [PF01822.21, score=53.7]; PAN domain [PF00024.28, score=24.0]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=45.1, Expect=1e-05]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=44.7, Expect=1e-05]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=47.8, Expect=9e-07]} {RNA1509_53783} {RNA1310_43597} {RNA815_9084.2}
52. MligTC455_39957 170 3.54 Mlig455_039809

Neo: -

Age: -

Region-specific R2: 4.733

Region-enriched R2: 5.232/0.00000

ADGB 1.686 - - - 0.727 - 0.959 Mlig455_039809 {REF} {Length: 7010} {tRNA: Ile(TAT),pseudo, score=33.4} {Pfam: Calpain family cysteine protease [PF00648.23, score=34.1]} {Human: ENSG00000118492, ADGB, androglobin, [Score=403, Expect=6e-115]} {Mouse: ENSMUSG00000050994, Adgb, androglobin, [Score=252, Expect=4e-67]} {Celegans: WBGene00000543, clp-2, CaLPain family, [Score=73.2, Expect=1e-12]} {Smed: dd_Smed_v6_10677_0_1, dd_Smed_v6_10677_0_1, [Score=253, Expect=8e-68]} {RNA1509_15950, RNA1509_59203} {RNA1310_4821, RNA1509_59203} {RNA1509_59203, RNA815_12506}
53. MligTC455_40878 355 7.39 Mlig455_014130

Neo: -

Age: -

1.686 - - - 0.734 - 0.952 Mlig455_014130 {REF} {Length: 1465} {RNA1509_7458} {RNA1310_36212} {RNA815_1610.1}
54. MligTC455_27279 104 2.17 Mlig455_052989, Mlig455_053048

Neo: -

Age: Up-Down-Up

ANK2 1.685 - - 0.708 0.977 - -

Mlig455_052989 {REF} {Length: 4886} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=154.0]; Ankyrin repeat [PF00023.32, score=133.3]; Ankyrin repeats (many copies) [PF13637.8, score=116.0]; Ankyrin repeat [PF13606.8, score=101.5]; Ankyrin repeats (many copies) [PF13857.8, score=84.2]; Mab-21 protein [PF03281.16, score=24.8]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=164, Expect=3e-40]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=158, Expect=2e-38]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=159, Expect=1e-38]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=149, Expect=8e-36]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=160, Expect=1e-39]} {RNA1509_49840} {RNA1310_24047} {RNA815_2400.1}

Mlig455_053048 {REF} {Length: 5337} {Pfam: Mab-21 protein [PF03281.16, score=25.9]} {RNA1509_57692} {RNA1310_3556, RNA1509_57692} {RNA1509_57692, RNA815_2305}
55. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 1.684 - - - 0.732 - 0.952 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
56. MligTC455_41537 411 8.57 Mlig455_058671

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.369

CCDC170 1.682 - - - - 0.732 0.950 Mlig455_058671 {REF} {Length: 4116} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [RH, Score=284, Expect=8e-84]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [RH, Score=274, Expect=4e-80]} {Dmel: FBgn0263079, CG43338, [RH, Score=117, Expect=1e-26]} {Smed: dd_Smed_v6_10140_0_1, dd_Smed_v6_10140_0_1, [RH, Score=304, Expect=4e-91]} {RNA1509_3115} {RNA1310_2598, RNA1509_3115} {RNA1509_3115, RNA815_746}
57. MligTC455_16952 79 1.65 Mlig455_001182

Neo: -

Age: -

1.679 - - - - 0.721 0.958 Mlig455_001182 {REF} {Length: 3873} {Smed: dd_Smed_v6_17523_0_1, dd_Smed_v6_17523_0_1, [RH, Score=67.0, Expect=3e-14]} {RNA1509_4618} {RNA1310_46281} {RNA815_28578}
58. MligTC455_48459 512 10.67 Mlig455_033033, Mlig455_044089

Neo: -

Age: logFC(26M/2M)=-0.316

Region-enriched R2: 2.708/0.00709

CSMD3 1.677 - - 0.724 - - 0.953

Mlig455_033033 {REF} {Length: 2936} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=194.1]} {Human: ENSG00000164796, CSMD3, CUB and Sushi multiple domains 3, [Score=161, Expect=2e-40]; ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=156, Expect=5e-39]; ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=155, Expect=1e-38]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=159, Expect=5e-40]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=152, Expect=9e-38]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [Score=198, Expect=2e-53]} {Celegans: WBGene00002976, lev-9, [Score=123, Expect=3e-29]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=2e-91]} {RNA1509_30688} {RNA1310_7890} {RNA815_3410.1}

Mlig455_044089 {REF} {Length: 2934} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=194.1]} {Human: ENSG00000164796, CSMD3, CUB and Sushi multiple domains 3, [Score=161, Expect=2e-40]; ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=156, Expect=5e-39]; ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=155, Expect=1e-38]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=159, Expect=5e-40]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=152, Expect=9e-38]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [Score=198, Expect=2e-53]} {Celegans: WBGene00002976, lev-9, [Score=123, Expect=3e-29]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=2e-91]} {RNA1509_30688} {RNA1310_7890, RNA1509_30688} {RNA1509_30688, RNA815_3410.1}
59. MligTC455_10299 72 1.51 Mlig455_023028, Mlig455_023125, Mlig455_023183

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.617

Region-enriched R2: 4.572/0.04281

ANGPTL1 1.674 - - - 0.957 - 0.717

Mlig455_023028 {REF} {Length: 2538} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=130.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=8e-29]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=112, Expect=1e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=114, Expect=2e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=112, Expect=9e-28]} {Dmel: FBgn0050280, CG30280, [Score=103, Expect=9e-26]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.8, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023125 {REF} {Length: 2398} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=127.5]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=112, Expect=2e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=107, Expect=1e-25]} {Mouse: ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=107, Expect=7e-26]} {Dmel: FBgn0050280, CG30280, [Score=92.8, Expect=6e-22]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=51.2, Expect=3e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023183 {REF} {Length: 2190} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=129.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=2e-28]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=110, Expect=9e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=113, Expect=4e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=110, Expect=6e-27]} {Dmel: FBgn0003326, sca, scabrous, [Score=104, Expect=8e-25]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.4, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}
60. MligTC455_13154 28 0.59 Mlig455_007824

Neo: -

Age: -

1.67 - - 0.719 - - 0.951 Mlig455_007824 {REF} {Length: 2457} {RNA1509_43477} {RNA1310_26398} {RNA815_11119}
61. MligTC455_19442 244 5.09 Mlig455_002080

Neo: -

Age: logFC(26M/2M)=-0.526

1.665 - - - - 0.707 0.958 Mlig455_002080 {REF} {Length: 2265} {Pfam: Aldehyde ferredoxin oxidoreductase, N-terminal domain [PF02730.17, score=18.6]} {RNA1509_40470} {RNA1310_22476.3} {RNA815_16128}
62. MligTC455_35259 2265 47.19 Mlig455_040978

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.606

Region-enriched R2: 1.588/0.00387

ADGRL2 1.664 - - - 0.701 - 0.963 Mlig455_040978 {REF} {Length: 10808} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=86.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=76.2]; PDZ domain [PF17820.3, score=67.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=52.3]; PDZ domain [PF13180.8, score=36.4]; ZU5 domain [PF00791.22, score=30.8]; Guanylate kinase [PF00625.23, score=22.4]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=174, Expect=1e-42]} {Mouse: ENSMUSG00000034917, Tjp3, tight junction protein 3, [RH, Score=172, Expect=9e-43]} {Dmel: FBgn0262614, pyd, polychaetoid, [RH, Score=232, Expect=8e-61]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=174, Expect=4e-43]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_17602, RNA1509_52679, RNA1509_58629} {RNA1310_236.2, RNA1509_17602, RNA1509_58629} {RNA1509_17602, RNA1509_58629, RNA815_77.1}
63. MligTC455_04605 20 0.42 Mlig455_039086

Neo: -

Age: Down-Up-Down

1.657 - - - - 0.705 0.952 Mlig455_039086 {REF} {Length: 1846} {RNA1310_72368}
64. MligTC455_29874 65 1.36 Mlig455_037947, Mlig455_068699

Neo: -

Age: logFC(26M/2M)=-0.467

ANKRD50 0.984 - - - - - 0.984

Mlig455_037947 {REF} {Length: 4099} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=309.9]; Ankyrin repeat [PF00023.32, score=295.0]; Ankyrin repeat [PF13606.8, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=228.6]; Ankyrin repeats (many copies) [PF13857.8, score=200.7]; Glutamine amidotransferase domain [PF13537.8, score=68.9]; PEGA domain [PF08308.13, score=35.0]; Mab-21 protein [PF03281.16, score=29.5]; Nucleoplasmin/nucleophosmin domain [PF03066.17, score=26.4]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=276, Expect=2e-75]; ENSG00000029534, ANK1, ankyrin 1, [Score=270, Expect=5e-73]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=274, Expect=8e-75]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=256, Expect=7e-69]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=258, Expect=1e-69]} {Smed: dd_Smed_v6_2072_0_29, dd_Smed_v6_2072_0_29, [Score=256, Expect=2e-71]} {RNA1509_26004, RNA1509_28959} {RNA1310_3906.1, RNA1509_28959} {RNA1509_28959, RNA815_1664.1}

Mlig455_068699 {REF} {Length: 2234} {Pfam: Mab-21 protein [PF03281.16, score=31.1]} {RNA1509_26004} {RNA1310_3906.1} {RNA815_1664.1}
65. MligTC455_28509 143 2.97 Mlig455_050246

Neo: -

Age: logFC(26M/2M)=-0.382

WDR49 0.982 - - - - - 0.982 Mlig455_050246 {REF} {Length: 5989} {Pfam: WD domain, G-beta repeat [PF00400.34, score=43.1]; EF-hand domain pair [PF13499.8, score=28.7]; Nup133 N terminal like [PF08801.13, score=22.4]; EF-hand domain pair [PF13833.8, score=21.5]; EF hand [PF00036.34, score=20.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=329, Expect=3e-96]} {Mouse: ENSMUSG00000044083, Efcab8, EF-hand calcium binding domain 8, [RH, Score=258, Expect=2e-70]} {Dmel: FBgn0267449, WDY, WD40 Y, [RH, Score=197, Expect=3e-51]} {Celegans: WBGene00010572, wdr-5.2, WD repeat-containing protein wdr-5.2, [Score=53.9, Expect=4e-07]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=302, Expect=2e-86]} {RNA1509_11289, RNA1509_17402, RNA1509_54041} {RNA1310_2314.2, RNA1509_11289, RNA1509_17402, RNA1509_54041} {RNA1509_11289, RNA1509_17402, RNA1509_54041, RNA815_2581}
66. MligTC455_27799 414 8.62 Mlig455_004285, Mlig455_004370

Neo: -

Age: Down-Up-Down

Region-specific R2: 3.850

Region-enriched R2: 5.047/0.00000

0.98 - - - 0.980 - -

Mlig455_004285 {REF} {Length: 650} {RNA1509_56105} {RNA1310_32410} {RNA815_17871.1}

Mlig455_004370 {REF} {Length: 1653} {RNA1509_56105} {RNA1310_32410} {RNA815_17871.1}
67. MligTC455_34707 705 14.69 Mlig455_047562, Mlig455_047574

Neo: -

Age: -

Region-enriched R8: 2.979/0.00000
Region-enriched R7: 1.790/0.00700

Regeneration-downregulated TP: -3.783

Regeneration-depleted TP: -3.783

ABCA1 0.98 - - - - - 0.980

Mlig455_047562 {REF} {Length: 7841} {Human: ENSG00000165029, ABCA1, ATP binding cassette subfamily A member 1, [Score=149, Expect=9e-40]; ENSG00000198691, ABCA4, ATP binding cassette subfamily A member 4, [Score=144, Expect=6e-38]} {Mouse: ENSMUSG00000015243, Abca1, ATP-binding cassette, sub-family A (ABC1), member 1, [Score=150, Expect=2e-40]} {Dmel: FBgn0031170, CG1718, [Score=150, Expect=1e-40]} {Celegans: WBGene00000022, abt-4, ABC Transporter family, [Score=122, Expect=5e-31]} {Smed: dd_Smed_v6_10304_0_1, dd_Smed_v6_10304_0_1, [Score=124, Expect=1e-31]} {RNA1509_2597} {RNA1310_287.1} {RNA815_111}

Mlig455_047574 {REF} {Length: 7925} {Pfam: ABC transporter [PF00005.29, score=177.3]; ABC-2 family transporter protein [PF12698.9, score=155.4]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=69.7]; Domain of unknown function (DUF4162) [PF13732.8, score=26.2]} {Human: ENSG00000165029, ABCA1, ATP binding cassette subfamily A member 1, [Score=1091, Expect=0.0]} {Mouse: ENSMUSG00000015243, Abca1, ATP-binding cassette, sub-family A (ABC1), member 1, [Score=1088, Expect=0.0]} {Dmel: FBgn0031170, CG1718, [Score=442, Expect=1e-128]} {Celegans: WBGene00000022, abt-4, ABC Transporter family, [Score=357, Expect=5e-100]} {Smed: dd_Smed_v6_2300_0_7, dd_Smed_v6_2300_0_7, [RH, Score=1004, Expect=0.0]} {RNA1509_2597, RNA1509_28410} {RNA1310_287.1, RNA1509_28410} {RNA1509_28410, RNA815_111}
68. MligTC455_23599 300 6.25 Mlig455_025579

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.645/0.00082

FBN2 0.976 - - - - - 0.976 Mlig455_025579 {REF} {Length: 10696} {Pfam: Calcium-binding EGF domain [PF07645.17, score=312.2]; Complement Clr-like EGF-like [PF12662.9, score=241.1]; Coagulation Factor Xa inhibitory site [PF14670.8, score=125.1]; EGF domain [PF12947.9, score=95.9]; EGF-like domain [PF00008.29, score=59.7]; Human growth factor-like EGF [PF12661.9, score=47.9]; Thrombospondin type 1 domain [PF00090.21, score=28.9]; MSP1 EGF domain 1 [PF12946.9, score=21.3]} {Human: ENSG00000138829, FBN2, fibrillin 2, [Score=250, Expect=2e-65]; ENSG00000166147, FBN1, fibrillin 1, [Score=248, Expect=1e-64]; ENSG00000142449, FBN3, fibrillin 3, [Score=243, Expect=3e-63]} {Mouse: ENSMUSG00000024598, Fbn2, fibrillin 2, [Score=253, Expect=1e-66]; ENSMUSG00000027204, Fbn1, fibrillin 1, [Score=251, Expect=5e-66]} {Dmel: FBgn0035798, frac, faulty attraction, [RH, Score=238, Expect=3e-62]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=192, Expect=3e-50]} {Smed: dd_Smed_v6_2649_0_2, dd_Smed_v6_2649_0_2, [Score=294, Expect=3e-79]} {RNA1509_13106} {RNA1310_487} {RNA815_5734}
69. MligTC455_24902 135 2.82 Mlig455_047157, Mlig455_047235

Neo: -

Age: Up-Down-Down

0.975 - - - 0.975 - -

Mlig455_047157 {REF} {Length: 2076} {Pfam: Pet100 [PF09803.11, score=37.6]} {RNA1509_11699} {RNA1310_24026} {RNA815_16164.2}

Mlig455_047235 {REF} {Length: 1828} {Pfam: Pet100 [PF09803.11, score=37.6]} {RNA1509_11699} {RNA1310_24026} {RNA815_16164.2}
70. MligTC455_42654 39 0.81 Mlig455_004817, Mlig455_004898

Neo: -

Age: Up-Down-Up

Regeneration-enriched R6: 11.200
Regeneration-enriched R5: 10.874
Regeneration-enriched R2: 9.867

LMLN2 0.974 - - - - - 0.974

Mlig455_004817 {REF} {Length: 3344} {Pfam: Leishmanolysin [PF01457.18, score=40.1]} {Human: ENSG00000283654, LMLN2, leishmanolysin like peptidase 2, [RH, Score=92.0, Expect=1e-18]} {Mouse: ENSMUSG00000114865, Gm29776, predicted gene, 29776, [RH, Score=88.2, Expect=2e-17]} {Dmel: FBgn0086359, Invadolysin, [Score=75.5, Expect=1e-13]} {Celegans: WBGene00012796, Y43F4A.1, Leishmanolysin-like peptidase, [Score=68.9, Expect=8e-12]} {Smed: dd_Smed_v6_9167_0_1, dd_Smed_v6_9167_0_1, [Score=75.5, Expect=7e-14]} {RNA1509_37538} {RNA1310_4126} {RNA815_1195}

Mlig455_004898 {REF} {Length: 3341} {Pfam: Leishmanolysin [PF01457.18, score=40.4]} {Human: ENSG00000283654, LMLN2, leishmanolysin like peptidase 2, [RH, Score=92.0, Expect=1e-18]} {Mouse: ENSMUSG00000114865, Gm29776, predicted gene, 29776, [RH, Score=89.0, Expect=1e-17]} {Dmel: FBgn0086359, Invadolysin, [Score=74.7, Expect=2e-13]} {Celegans: WBGene00012796, Y43F4A.1, Leishmanolysin-like peptidase, [Score=69.3, Expect=8e-12]} {Smed: dd_Smed_v6_9167_0_1, dd_Smed_v6_9167_0_1, [Score=75.9, Expect=6e-14]} {RNA1509_37538} {RNA1310_4126} {RNA815_1195}
71. MligTC455_25823 51 1.06 Mlig455_027371

Neo: -

Age: -

0.973 - - - - - 0.973 Mlig455_027371 {REF} {Length: 3017} {TRANSSPLICED} {RNA1509_20973} {RNA1310_21777} {RNA815_13901.1}
72. MligTC455_33563 304 6.34 Mlig455_003859, Mlig455_003860, Mlig455_006554, Mlig455_006555, Mlig455_016950, Mlig455_018481, Mlig455_018483, Mlig455_031341, Mlig455_031342, Mlig455_057217, Mlig455_065069, Mlig455_070194

Neo: -

Age: Down-Up-Down

0.973 - - 0.973 - - -

Mlig455_003859 {REF} {Length: 1409} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_003860 {REF} {Length: 1410} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667, RNA1509_18509} {RNA1509_18509, RNA815_14362}

Mlig455_006554 {REF} {Length: 1403} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_006555 {REF} {Length: 1408} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_016950 {REF} {Length: 1742} {Pfam: RNase H-like domain found in reverse transcriptase [PF17917.3, score=103.7]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=80.0]; Integrase zinc binding domain [PF17921.3, score=51.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=33.5]} {Mouse: ENSMUSG00000061186, Sfmbt2, Scm-like with four mbt domains 2, [Score=68.9, Expect=1e-11]} {Smed: dd_Smed_v6_15498_0_18, dd_Smed_v6_15498_0_18, [Score=99.0, Expect=2e-22]} {RNA1509_38544} {RNA1310_2645.1} {RNA815_16906}

Mlig455_018481 {REF} {Length: 6807} {Pfam: RNase H-like domain found in reverse transcriptase [PF17917.3, score=102.5]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=77.2]} {Mouse: ENSMUSG00000024246, Thumpd2, THUMP domain containing 2, [Score=55.8, Expect=1e-07]} {Smed: dd_Smed_v6_15498_0_18, dd_Smed_v6_15498_0_18, [Score=94.4, Expect=8e-21]} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_018483 {REF} {Length: 1402} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_031341 {REF} {Length: 1404} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_031342 {REF} {Length: 1404} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_057217 {REF} {Length: 1399} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_065069 {REF} {Length: 1404} {TRANSSPLICED} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}

Mlig455_070194 {REF} {Length: 1194} {RNA1509_18509} {RNA1310_27667} {RNA815_14362}
73. MligTC455_04625 54 1.12 Mlig455_031551, Mlig455_031554

Neo: -

Age: -

FHAD1 0.972 - - - - - 0.972

Mlig455_031551 {REF} {Length: 1252} {Pfam: FHA domain [PF00498.28, score=38.1]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.3]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=66.2, Expect=1e-11]} {RNA1509_11172} {RNA1310_2117.1} {RNA815_31030}

Mlig455_031554 {REF} {Length: 5287} {Pfam: FHA domain [PF00498.28, score=36.7]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.0]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [Score=130, Expect=4e-31]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=129, Expect=1e-29]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=129, Expect=1e-29]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=252, Expect=3e-68]} {RNA1509_11172} {RNA1310_2117.1} {RNA815_6949}
74. MligTC455_20209 78 1.63 Mlig455_034769

Neo: -

Age: -

0.972 - - - 0.972 - - Mlig455_034769 {REF} {Length: 2528} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=55.9]} {RNA1310_29903.1} {RNA815_52525}
75. MligTC455_40917 136 2.84 Mlig455_054293, Mlig455_054369

Neo: -

Age: -

0.972 - - - 0.972 - -

Mlig455_054293 {REF} {Length: 451} {NoTransDecoderORF} {RNA1310_68874} {RNA815_30304}

Mlig455_054369 {REF} {Length: 490} {NoTransDecoderORF} {RNA1310_68874} {RNA815_30304}
76. MligTC455_38488 104 2.17 Mlig455_028945

Neo: -

Age: -

0.971 - - - 0.971 - - Mlig455_028945 {REF} {Length: 1892} {RNA1509_8169} {RNA1310_1629} {RNA815_9829.1}
77. MligTC455_38489 116 2.42 Mlig455_012152, Mlig455_028944

Neo: -

Age: -

ANK1, ANK3 0.971 - - - 0.971 - -

Mlig455_012152 {REF} {Length: 4233} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=378.4]; Ankyrin repeats (many copies) [PF13637.8, score=260.0]; Ankyrin repeats (many copies) [PF13857.8, score=234.7]; Ankyrin repeat [PF00023.32, score=229.8]; Ankyrin repeat [PF13606.8, score=215.9]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=313, Expect=3e-87]; ENSG00000145362, ANK2, ankyrin 2, [Score=298, Expect=2e-82]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=305, Expect=2e-84]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=295, Expect=1e-82]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=290, Expect=2e-79]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=298, Expect=1e-83]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=286, Expect=2e-80]} {Smed: dd_Smed_v6_2072_0_30, dd_Smed_v6_2072_0_30, [Score=292, Expect=8e-84]} {RNA1509_29504} {RNA1310_1629, RNA1509_29504} {RNA1509_29504, RNA815_5687}

Mlig455_028944 {REF} {Length: 475} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=35.2]; Ankyrin repeat [PF13606.8, score=32.6]; Ankyrin repeats (many copies) [PF13857.8, score=32.5]; Ankyrin repeat [PF00023.32, score=31.7]; Ankyrin repeats (many copies) [PF13637.8, score=30.3]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=49.7, Expect=2e-08]; ENSG00000145362, ANK2, ankyrin 2, [Score=49.3, Expect=2e-08]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=49.7, Expect=1e-08]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=49.3, Expect=2e-08]; ENSMUSG00000005251, Ripk4, receptor-interacting serine-threonine kinase 4, [Score=48.1, Expect=4e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=53.9, Expect=3e-10]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=50.8, Expect=3e-09]} {Smed: dd_Smed_v6_2072_0_6, dd_Smed_v6_2072_0_6, [Score=49.7, Expect=6e-09]} {RNA1509_29504} {RNA1310_1629} {RNA815_5687}
78. MligTC455_54126 566 11.79 Mlig455_000053

Neo: -

Age: -

SPEF1 0.97 - - - - - 0.970 Mlig455_000053 {REF} {Length: 1286} {TRANSSPLICED} {Pfam: CH-like domain in sperm protein [PF06294.13, score=114.7]; CAMSAP CH domain [PF11971.10, score=53.6]} {Human: ENSG00000101222, SPEF1, sperm flagellar 1, [RH, Score=172, Expect=1e-52]} {Mouse: ENSMUSG00000027329, Spef1, sperm flagellar 1, [RH, Score=180, Expect=3e-56]} {Dmel: FBgn0030722, CG12395, [Score=65.5, Expect=2e-12]} {Smed: dd_Smed_v6_5648_0_1, dd_Smed_v6_5648_0_1, [RH, Score=272, Expect=5e-93]} {RNA1509_48542} {RNA1310_25346.2} {RNA815_11607}
79. MligTC455_38810 655 13.64 Mlig455_021157, Mlig455_021360, Mlig455_021587

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.289

Region-enriched R2: 2.927/0.00001

NELL2 0.969 - - - - - 0.969

Mlig455_021157 {REF} {Length: 4103} {Smed: dd_Smed_v6_13075_0_2, dd_Smed_v6_13075_0_2, [Score=57.8, Expect=4e-08]} {RNA1509_22586} {RNA1310_1033} {RNA815_17785}

Mlig455_021360 {REF} {Length: 7457} {Pfam: Calcium-binding EGF domain [PF07645.17, score=34.6]; EGF domain [PF12947.9, score=33.5]; TNFR/NGFR cysteine-rich region [PF00020.20, score=27.7]; Complement Clr-like EGF-like [PF12662.9, score=20.4]} {Human: ENSG00000184613, NELL2, neural EGFL like 2, [Score=63.5, Expect=4e-09]; ENSG00000168743, NPNT, nephronectin, [Score=62.4, Expect=6e-09]; ENSG00000165973, NELL1, neural EGFL like 1, [Score=60.8, Expect=3e-08]} {Mouse: ENSMUSG00000000402, Egfl6, EGF-like-domain, multiple 6, [Score=63.2, Expect=3e-09]; ENSMUSG00000022454, Nell2, NEL-like 2, [Score=63.2, Expect=3e-09]; ENSMUSG00000002885, Adgre5, adhesion G protein-coupled receptor E5, [Score=62.0, Expect=6e-09]; ENSMUSG00000040998, Npnt, nephronectin, [Score=62.0, Expect=5e-09]} {Dmel: FBgn0035798, frac, faulty attraction, [Score=54.7, Expect=1e-06]} {Celegans: WBGene00022816, fbn-1, FBN-1A.1; FiBrilliN homolog, [Score=68.9, Expect=4e-11]} {Smed: dd_Smed_v6_13075_0_1, dd_Smed_v6_13075_0_1, [RH, Score=146, Expect=9e-35]} {RNA1509_49441} {RNA1310_699, RNA1509_49441} {RNA1509_49441, RNA815_6324}

Mlig455_021587 {REF} {Length: 2362} {RNA1509_22586} {RNA1310_1033} {RNA815_22832}
80. MligTC455_21721 1177 24.51 Mlig455_052943, Mlig455_053013

Neo: -

Age: -

TRPM3 0.967 - - - - - 0.967

Mlig455_052943 {REF} {Length: 4423} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.0]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=52.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=521, Expect=2e-158]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=522, Expect=1e-158]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=484, Expect=1e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=362, Expect=8e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=607, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}

Mlig455_053013 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.1]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=53.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=8e-157]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=519, Expect=2e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=8e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=605, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1, RNA1509_4847} {RNA1509_4847, RNA815_652.1}
81. MligTC455_33288 692 14.41 Mlig455_061850

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.145

Region-enriched R2: 4.075/0.00000

0.967 - - - 0.967 - - Mlig455_061850 {REF} {Length: 889} {RNA1509_48963} {RNA1310_87307} {RNA815_23468}
82. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 0.967 - - - - - 0.967 Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
83. MligTC455_01751 113 2.35 Mlig455_019682

Neo: -

Age: -

0.966 - - - - - 0.966 Mlig455_019682 {REF} {Length: 722} {RNA1509_50956} {RNA1310_14959.1} {RNA815_9852.1}
84. MligTC455_29101 37 0.77 Mlig455_061343

Neo: -

Age: logFC(26M/2M)=0.428

0.966 - - - - - 0.966 Mlig455_061343 {REF} {Length: 9097} {Pfam: Zinc knuckle [PF00098.25, score=33.9]} {Celegans: WBGene00017210, F07E5.5, [Score=48.9, Expect=9e-06]} {RNA1509_50802, RNA1509_9188} {RNA1310_234.1, RNA1509_50802} {RNA1509_50802, RNA815_23.1}
85. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

0.966 - - - - - 0.966 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
86. MligTC455_04854 57 1.18 Mlig455_032030

Neo: -

Age: -

Region-enriched R2: 5.099/0.03475

0.964 - - - 0.964 - - Mlig455_032030 {REF} {Length: 1388} {RNA1310_84273}
87. MligTC455_28202 337 7.03 Mlig455_063876

Neo: -

Age: -

Region-enriched R2: 3.393/0.00249

0.964 - - - - - 0.964 Mlig455_063876 {REF} {Length: 9210} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [Score=102, Expect=3e-23]} {RNA1509_30620, RNA1509_41832, RNA1509_45836} {RNA1310_13656, RNA1509_41832, RNA1509_45836} {RNA1509_41832, RNA1509_45836, RNA815_1450.1}
88. MligTC455_39222 213 4.44 Mlig455_064653, Mlig455_064686

Neo: -

Age: -

Region-enriched R2: 4.317/0.00597

0.964 - - - - - 0.964

Mlig455_064653 {REF} {Length: 2836} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.9, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=7e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_56255} {RNA1310_13407} {RNA815_38407}

Mlig455_064686 {REF} {Length: 3820} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.5, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=8e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_50956} {RNA1310_13407} {RNA815_38407}
89. MligTC455_41181 708 14.76 Mlig455_049760

Neo: -

Age: logFC(26M/2M)=-0.377

Region-enriched R2: 2.010/0.02984

AK5 0.963 - - - - - 0.963 Mlig455_049760 {REF} {Length: 2835} {TRANSSPLICED} {Pfam: Adenylate kinase [PF00406.24, score=105.1]; AAA domain [PF13207.8, score=87.6]; AAA domain [PF13238.8, score=49.8]; AAA domain [PF13671.8, score=35.6]; IQ calmodulin-binding motif [PF00612.29, score=33.6]; AAA ATPase domain [PF13191.8, score=29.8]; AAA domain [PF13521.8, score=22.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.4]; AAA domain [PF13245.8, score=20.1]} {Human: ENSG00000154027, AK5, adenylate kinase 5, [RH, Score=223, Expect=6e-64]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [RH, Score=222, Expect=1e-63]} {Dmel: FBgn0032083, CG9541, [RH, Score=109, Expect=1e-24]} {Celegans: WBGene00008746, F13E6.2, [Score=126, Expect=7e-30]} {Smed: dd_Smed_v6_5119_0_1, dd_Smed_v6_5119_0_1, [RH, Score=266, Expect=1e-77]} {RNA1509_14765, RNA1509_30132} {RNA1310_6179.1, RNA1509_14765, RNA1509_30132} {RNA1509_14765, RNA1509_30132, RNA815_3037}
90. MligTC455_44661 48 1 Mlig455_038182

Neo: -

Age: logFC(26M/2M)=-0.564

ANO7 0.963 - - - 0.963 - - Mlig455_038182 {REF} {Length: 3290} {Pfam: Calcium-activated chloride channel [PF04547.14, score=599.2]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=223.8]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=582, Expect=0.0]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=572, Expect=0.0]} {Dmel: FBgn0038721, subdued, [Score=422, Expect=3e-132]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=163, Expect=4e-41]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=670, Expect=0.0]} {RNA1509_46639} {RNA1310_1412.2} {RNA815_15650}
91. MligTC455_10082 430 8.96 Mlig455_000403, Mlig455_000471

Neo: -

Age: -

Region-enriched R2: 2.917/0.00040

0.961 - - - 0.961 - -

Mlig455_000403 {REF} {Length: 747} {RNA1310_48386} {RNA815_37422}

Mlig455_000471 {REF} {Length: 750} {RNA1310_48386} {RNA815_37422}
92. MligTC455_17562 108 2.25 Mlig455_022496

Neo: -

Age: -

NECAB3 0.961 - - - 0.961 - - Mlig455_022496 {REF} {Length: 1499} {Pfam: EF hand [PF00036.34, score=34.0]; EF-hand domain [PF13405.8, score=33.4]; EF-hand domain pair [PF13833.8, score=29.2]; EF-hand domain pair [PF13499.8, score=28.3]; Antibiotic biosynthesis monooxygenase [PF03992.18, score=22.0]; EF hand [PF13202.8, score=21.3]} {Human: ENSG00000125967, NECAB3, N-terminal EF-hand calcium binding protein 3, [RH, Score=189, Expect=7e-57]; ENSG00000123119, NECAB1, N-terminal EF-hand calcium binding protein 1, [RH, Score=186, Expect=1e-55]} {Mouse: ENSMUSG00000040536, Necab1, N-terminal EF-hand calcium binding protein 1, [RH, Score=191, Expect=7e-58]; ENSMUSG00000027489, Necab3, N-terminal EF-hand calcium binding protein 3, [RH, Score=191, Expect=9e-58]} {RNA1509_46831} {RNA1310_24461} {RNA815_25216}
93. MligTC455_30620 201 4.18 Mlig455_058938

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.526

0.961 - - - - - 0.961 Mlig455_058938 {REF} {Length: 4222} {Pfam: Mab-21 protein [PF03281.16, score=39.0]} {RNA1509_51832, RNA1509_59365} {RNA1310_6164, RNA1509_59365} {RNA1509_59365, RNA815_1489.1}
94. MligTC455_42994 1521 31.7 Mlig455_035840

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

Region-enriched R2: 1.854/0.00052

0.961 - - - - - 0.961 Mlig455_035840 {REF} {Length: 1436} {RNA1509_29485, RNA1509_42231} {RNA1310_26640, RNA1509_29485, RNA1509_42231} {RNA1509_29485, RNA1509_42231, RNA815_37260}
95. MligTC455_10083 397 8.27 Mlig455_000410, Mlig455_000477

Neo: -

Age: logFC(26M/2M)=1.533

Region-enriched R2: 3.033/0.00070

0.96 - - - 0.960 - -

Mlig455_000410 {REF} {Length: 1205} {RNA1509_50537} {RNA1310_48386} {RNA815_37422}

Mlig455_000477 {REF} {Length: 1206} {RNA1509_50537} {RNA1310_48386} {RNA815_37422}
96. MligTC455_10953 148 3.08 Mlig455_060864, Mlig455_063528

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.497/0.01237
Region-enriched R5: 3.064/0.03185

KCNH7 0.96 - - - 0.960 - -

Mlig455_060864 {REF} {Length: 7144} {Pfam: Ion transport protein [PF00520.33, score=117.5]; Cyclic nucleotide-binding domain [PF00027.31, score=52.7]; Ion channel [PF07885.18, score=45.4]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=777, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=760, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=751, Expect=0.0]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=776, Expect=0.0]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=761, Expect=0.0]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=751, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [Score=741, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=712, Expect=0.0]} {Smed: dd_Smed_v6_12621_0_1, dd_Smed_v6_12621_0_1, [Score=798, Expect=0.0]} {RNA1509_40124} {RNA1310_4074} {RNA815_8044}

Mlig455_063528 {REF} {Length: 734} {NoTransDecoderORF}
97. MligTC455_29012 227 4.74 Mlig455_004572

Neo: -

Age: Down-Down-Up

TMEM30A 0.96 - - - - - 0.960 Mlig455_004572 {REF} {Length: 3160} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=265.5]} {Human: ENSG00000112697, TMEM30A, transmembrane protein 30A, [RH, Score=234, Expect=7e-73]} {Mouse: ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [RH, Score=241, Expect=7e-76]} {Dmel: FBgn0030752, CG9947, [RH, Score=294, Expect=9e-97]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [Score=246, Expect=3e-78]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=275, Expect=2e-89]} {RNA1509_38539} {RNA1310_9371} {RNA815_12157}
98. MligTC455_04626 114 2.37 Mlig455_056977

Neo: -

Age: logFC(26M/2M)=-0.594

FHAD1 0.959 - - - - - 0.959 Mlig455_056977 {REF} {Length: 5197} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=36.8]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.1]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [Score=130, Expect=1e-29]} {Mouse: ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=127, Expect=3e-29]; ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=127, Expect=3e-29]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=252, Expect=2e-68]} {RNA1509_11172} {RNA1310_2117.1, RNA1509_11172} {RNA1509_11172, RNA815_6949}
99. MligTC455_14375 163 3.4 Mlig455_056945

Neo: -

Age: -

0.959 - - - 0.959 - - Mlig455_056945 {REF} {Length: 1764} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=49.6]} {Smed: dd_Smed_v6_32358_0_1, dd_Smed_v6_32358_0_1, [Score=94.4, Expect=4e-22]} {RNA1509_48719} {RNA1310_16266.1} {RNA815_10544.2}
100. MligTC455_15489 64 1.34 Mlig455_007936, Mlig455_008038

Neo: -

Age: -

Region-enriched R2: 5.213/0.00031

DIRAS2 0.959 - - - - - 0.959

Mlig455_007936 {REF} {Length: 1262} {Pfam: Ras family [PF00071.24, score=149.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=66.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.2]; RsgA GTPase [PF03193.18, score=27.4]; ADP-ribosylation factor family [PF00025.23, score=24.3]; Ferrous iron transport protein B [PF02421.20, score=19.3]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.0]} {Human: ENSG00000165023, DIRAS2, DIRAS family GTPase 2, [RH, Score=263, Expect=1e-88]} {Mouse: ENSMUSG00000047842, Diras2, DIRAS family, GTP-binding RAS-like 2, [RH, Score=262, Expect=2e-88]} {Dmel: FBgn0037754, CG8500, [RH, Score=237, Expect=3e-78]} {Celegans: WBGene00016911, drn-1, GTP-binding protein drn-1, [RH, Score=236, Expect=4e-78]} {Smed: dd_Smed_v6_10778_0_1, dd_Smed_v6_10778_0_1, [RH, Score=245, Expect=3e-82]} {RNA1509_35041} {RNA1310_23187} {RNA815_16187}

Mlig455_008038 {REF} {Length: 1497} {Pfam: Ras family [PF00071.24, score=149.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=66.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.1]; RsgA GTPase [PF03193.18, score=27.5]; ADP-ribosylation factor family [PF00025.23, score=24.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.1]; Ferrous iron transport protein B [PF02421.20, score=19.1]} {Human: ENSG00000165023, DIRAS2, DIRAS family GTPase 2, [RH, Score=263, Expect=1e-88]} {Mouse: ENSMUSG00000047842, Diras2, DIRAS family, GTP-binding RAS-like 2, [RH, Score=262, Expect=3e-88]} {Dmel: FBgn0037754, CG8500, [RH, Score=237, Expect=4e-78]} {Celegans: WBGene00016911, drn-1, GTP-binding protein drn-1, [RH, Score=236, Expect=5e-78]} {Smed: dd_Smed_v6_10778_0_1, dd_Smed_v6_10778_0_1, [RH, Score=246, Expect=4e-82]} {RNA1509_35041} {RNA1310_23187, RNA1509_35041} {RNA1509_35041, RNA815_16187}

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