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Results for MligTC455_43847

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_43847 3526 73.45 Mlig455_054896

Neo: -

Age: logFC(26M/2M)=0.475

Region-enriched R4: 1.008/0.00929

Regeneration-upregulated BL: 1.126

Regeneration-enriched BL: 1.126

PSMC4 Mlig455_054896 {REF} {Length: 1696} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=110.1]; AAA+ lid domain [PF17862.3, score=40.2]; AAA domain (Cdc48 subfamily) [PF07724.16, score=34.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=27.8]; AAA ATPase domain [PF13191.8, score=25.8]; AAA domain [PF13238.8, score=22.3]; AAA domain [PF13401.8, score=22.3]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=21.8]; AAA domain [PF13521.8, score=21.0]; Protein of unknown function (DUF815) [PF05673.15, score=20.3]; Magnesium chelatase, subunit ChlI [PF01078.23, score=20.0]; AAA domain [PF13671.8, score=19.8]; TIP49 P-loop domain [PF06068.15, score=18.1]} {Human: ENSG00000281221, PSMC4, proteasome 26S subunit, ATPase 4, [Score=373, Expect=9e-130]; ENSG00000013275, PSMC4, proteasome 26S subunit, ATPase 4, [Score=373, Expect=9e-130]} {Mouse: ENSMUSG00000030603, Psmc4, proteasome (prosome, macropain) 26S subunit, ATPase, 4, [Score=372, Expect=4e-130]} {Dmel: FBgn0028686, Rpt3, Regulatory particle triple-A ATPase 3, [Score=372, Expect=1e-129]} {Celegans: WBGene00004503, rpt-3, Probable 26S protease regulatory subunit 6B, [Score=338, Expect=1e-116]} {Smed: dd_Smed_v6_1279_0_1, dd_Smed_v6_1279_0_1, [Score=374, Expect=5e-131]} {RNA1509_9119} {RNA1310_15862} {RNA815_6256.1}

Cumulative graph for MligTC455_43847

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.662 6.342 0.27543 0.92595
RegionR2 -0.282 6.342 0.39816 0.79243
RegionR3 -0.269 6.342 0.32927 0.86716
RegionR4 1.008 6.342 0.00086 0.00929
RegionR5 0.64 6.342 0.00916 0.05419
RegionR6 0.136 6.342 0.61809 1.00000
RegionR7 -0.177 6.342 0.58502 1.00000
RegionR8 -0.393 6.342 0.32190 0.95564

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.618 6.342 0.42029 1.00000
RegenerationR2 0.038 6.342 0.90418 1.00000
RegenerationR3 0.634 6.342 0.06190 0.42076
RegenerationR4 -0.34 6.342 0.31197 0.75190
RegenerationR5 -0.037 6.342 0.90580 1.00000
RegenerationR6 0.93 6.342 0.00404 0.07605
RegenerationBL 1.126 6.342 0.00028 0.00949 Specific for BL: 1.126
RegenerationTP 0.284 6.342 0.44531 0.86456


Genes with expression patterns similar to MligTC455_43847

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_43847 3526 73.45 Mlig455_054896

Neo: -

Age: logFC(26M/2M)=0.475

Region-enriched R4: 1.008/0.00929

Regeneration-upregulated BL: 1.126

Regeneration-enriched BL: 1.126

PSMC4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_054896 {REF} {Length: 1696} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=110.1]; AAA+ lid domain [PF17862.3, score=40.2]; AAA domain (Cdc48 subfamily) [PF07724.16, score=34.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=27.8]; AAA ATPase domain [PF13191.8, score=25.8]; AAA domain [PF13238.8, score=22.3]; AAA domain [PF13401.8, score=22.3]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=21.8]; AAA domain [PF13521.8, score=21.0]; Protein of unknown function (DUF815) [PF05673.15, score=20.3]; Magnesium chelatase, subunit ChlI [PF01078.23, score=20.0]; AAA domain [PF13671.8, score=19.8]; TIP49 P-loop domain [PF06068.15, score=18.1]} {Human: ENSG00000281221, PSMC4, proteasome 26S subunit, ATPase 4, [Score=373, Expect=9e-130]; ENSG00000013275, PSMC4, proteasome 26S subunit, ATPase 4, [Score=373, Expect=9e-130]} {Mouse: ENSMUSG00000030603, Psmc4, proteasome (prosome, macropain) 26S subunit, ATPase, 4, [Score=372, Expect=4e-130]} {Dmel: FBgn0028686, Rpt3, Regulatory particle triple-A ATPase 3, [Score=372, Expect=1e-129]} {Celegans: WBGene00004503, rpt-3, Probable 26S protease regulatory subunit 6B, [Score=338, Expect=1e-116]} {Smed: dd_Smed_v6_1279_0_1, dd_Smed_v6_1279_0_1, [Score=374, Expect=5e-131]} {RNA1509_9119} {RNA1310_15862} {RNA815_6256.1}
2. MligTC455_43846 3542 73.79 Mlig455_054802

Neo: -

Age: -

Region-enriched R4: 1.013/0.00780

Regeneration-upregulated BL: 1.109

Regeneration-enriched BL: 1.109

PSMC4 5.985 1.000 1.000 0.996 0.996 1.000 0.993 Mlig455_054802 {REF} {Length: 1813} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=146.8]; Proteasomal ATPase OB C-terminal domain [PF16450.7, score=46.4]; AAA+ lid domain [PF17862.3, score=37.9]; AAA domain (Cdc48 subfamily) [PF07724.16, score=33.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=31.7]; AAA ATPase domain [PF13191.8, score=25.0]; AAA domain [PF13401.8, score=22.0]; AAA domain [PF13238.8, score=21.2]; Protein of unknown function (DUF815) [PF05673.15, score=20.9]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=20.6]; AAA domain [PF13521.8, score=19.4]; Magnesium chelatase, subunit ChlI [PF01078.23, score=18.7]; TIP49 P-loop domain [PF06068.15, score=18.0]} {Human: ENSG00000013275, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]; ENSG00000281221, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]} {Mouse: ENSMUSG00000030603, Psmc4, proteasome (prosome, macropain) 26S subunit, ATPase, 4, [RH, Score=715, Expect=0.0]} {Dmel: FBgn0028686, Rpt3, Regulatory particle triple-A ATPase 3, [RH, Score=702, Expect=0.0]} {Celegans: WBGene00004503, rpt-3, Probable 26S protease regulatory subunit 6B, [RH, Score=629, Expect=0.0]} {Smed: dd_Smed_v6_1279_0_1, dd_Smed_v6_1279_0_1, [RH, Score=695, Expect=0.0]} {RNA1509_2743, RNA1509_41659} {RNA1310_15862, RNA1509_2743, RNA1509_41659} {RNA1509_2743, RNA1509_41659, RNA815_6256.1}
3. MligTC455_19667 1945 40.52 Mlig455_048916

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.226

METAP2 1.746 - - - 0.790 0.956 - Mlig455_048916 {REF} {Length: 1920} {TRANSSPLICED} {Pfam: Metallopeptidase family M24 [PF00557.26, score=151.8]} {Human: ENSG00000111142, METAP2, methionyl aminopeptidase 2, [RH, Score=580, Expect=0.0]} {Mouse: ENSMUSG00000036112, Metap2, methionine aminopeptidase 2, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0283478, und, uninitiated, [RH, Score=563, Expect=0.0]} {Celegans: WBGene00003130, map-2, Methionine AminoPeptidase, [RH, Score=553, Expect=0.0]} {Smed: dd_Smed_v6_2809_0_1, dd_Smed_v6_2809_0_1, [RH, Score=561, Expect=0.0]} {RNA1509_21855, RNA1509_3506, RNA1509_35350, RNA1509_44852, RNA1509_47551, RNA1509_5949, RNA1509_6431} {RNA1310_15348, RNA1509_21855, RNA1509_3506, RNA1509_35350, RNA1509_44852, RNA1509_47551, RNA1509_5949, RNA1509_6431} {RNA1509_21855, RNA1509_3506, RNA1509_35350, RNA1509_44852, RNA1509_47551, RNA1509_5949, RNA1509_6431, RNA815_5667}
4. MligTC455_16709 1302 27.12 Mlig455_029518

Neo: -

Age: -

Region-enriched R3: 1.855/0.00908

SLC13A3 0.968 - - - - 0.968 - Mlig455_029518 {REF} {Length: 2726} {Pfam: Sodium:sulfate symporter transmembrane region [PF00939.21, score=302.1]; Citrate transporter [PF03600.18, score=114.3]} {Human: ENSG00000158296, SLC13A3, solute carrier family 13 member 3, [Score=406, Expect=7e-134]} {Mouse: ENSMUSG00000018459, Slc13a3, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, [Score=384, Expect=3e-125]; ENSMUSG00000029700, Slc13a1, solute carrier family 13 (sodium/sulfate symporters), member 1, [Score=367, Expect=8e-119]; ENSMUSG00000020805, Slc13a5, solute carrier family 13 (sodium-dependent citrate transporter), member 5, [Score=366, Expect=1e-118]; ENSMUSG00000001095, Slc13a2, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, [Score=366, Expect=1e-118]; ENSMUSG00000029843, Slc13a4, solute carrier family 13 (sodium/sulfate symporters), member 4, [Score=365, Expect=5e-118]} {Dmel: FBgn0036816, Indy, I'm not dead yet, [Score=281, Expect=1e-86]} {Celegans: WBGene00003517, nac-1, Sodium-dependent low-affinity dicarboxylate transporter 1, [Score=317, Expect=7e-100]} {Smed: dd_Smed_v6_12964_0_8, dd_Smed_v6_12964_0_8, [Score=360, Expect=6e-117]} {RNA1509_9551} {RNA1310_8761.2} {RNA815_3645}
5. MligTC455_33893 2159 44.99 Mlig455_048120

Neo: -

Age: -

Region-enriched R5: 1.314/0.00000
Region-enriched R4: 1.116/0.00488

SHMT2 0.958 - - - - 0.958 - Mlig455_048120 {REF} {Length: 2300} {TRANSSPLICED} {Pfam: Serine hydroxymethyltransferase [PF00464.21, score=623.4]} {Human: ENSG00000182199, SHMT2, serine hydroxymethyltransferase 2, [Score=595, Expect=0.0]} {Mouse: ENSMUSG00000020534, Shmt1, serine hydroxymethyltransferase 1 (soluble), [RH, Score=562, Expect=0.0]} {Dmel: FBgn0029823, Shmt, Serine hydroxymethyl transferase, [RH, Score=576, Expect=0.0]} {Celegans: WBGene00003214, mel-32, Serine hydroxymethyltransferase, [RH, Score=589, Expect=0.0]} {Smed: dd_Smed_v6_2312_0_1, dd_Smed_v6_2312_0_1, [RH, Score=588, Expect=0.0]} {RNA1509_2637, RNA1509_8192} {RNA1310_8717.2, RNA1509_2637, RNA1509_8192} {RNA1509_2637, RNA1509_8192, RNA815_3601}
6. MligTC455_44116 15886 330.96 Mlig455_070259

Neo: -

Age: logFC(26M/2M)=-0.821

Region-enriched R3: 1.626/0.01191

BHMT 0.953 - - - - 0.953 - Mlig455_070259 {REF} {Length: 1926} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=168.1]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=562, Expect=0.0]} {Mouse: ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=570, Expect=0.0]; ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=570, Expect=0.0]} {Celegans: WBGene00010988, metr-1, Probable methionine synthase, [Score=52.4, Expect=5e-07]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942} {RNA1310_16129.1, RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942} {RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942, RNA815_5900.1}
7. MligTC455_18994 2791 58.15 Mlig455_032925, Mlig455_032939

Neo: -

Age: -

Region-enriched R5: 1.616/0.00346
Region-enriched R6: 1.503/0.04971

KLKB1 0.952 - - - - 0.952 -

Mlig455_032925 {REF} {Length: 1754} {Pfam: Trypsin [PF00089.28, score=100.7]} {Human: ENSG00000164344, KLKB1, kallikrein B1, [Score=80.9, Expect=3e-16]} {Mouse: ENSMUSG00000049291, Prss38, protease, serine 38, [Score=71.2, Expect=2e-13]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=70.1, Expect=1e-12]; ENSMUSG00000059042, Klk1b9, kallikrein 1-related peptidase b9, [Score=68.6, Expect=8e-13]} {Dmel: FBgn0033362, CG8172, [Score=69.3, Expect=7e-13]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=74.3, Expect=3e-14]} {Smed: dd_Smed_v6_7481_0_1, dd_Smed_v6_7481_0_1, [RH, Score=101, Expect=1e-24]} {RNA1509_10182, RNA1509_10813} {RNA1310_3302.1, RNA1509_10182, RNA1509_10813} {RNA1509_10182, RNA1509_10813, RNA815_8189.1}

Mlig455_032939 {REF} {Length: 1229} {TRANSSPLICED} {Pfam: Trypsin [PF00089.28, score=100.8]} {Human: ENSG00000164344, KLKB1, kallikrein B1, [Score=80.9, Expect=3e-16]} {Mouse: ENSMUSG00000049291, Prss38, protease, serine 38, [Score=70.9, Expect=2e-13]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=70.5, Expect=7e-13]; ENSMUSG00000059042, Klk1b9, kallikrein 1-related peptidase b9, [Score=68.2, Expect=9e-13]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=67.4, Expect=7e-12]} {Dmel: FBgn0033362, CG8172, [Score=69.7, Expect=4e-13]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=74.3, Expect=2e-14]} {Smed: dd_Smed_v6_7481_0_1, dd_Smed_v6_7481_0_1, [RH, Score=101, Expect=1e-24]} {RNA1509_10182} {RNA1310_3302.1} {RNA815_8189.1}
8. MligTC455_16708 1126 23.47 Mlig455_029498

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.797

Region-enriched R4: 1.447/0.01642
Region-enriched R3: 1.379/0.01773
Region-enriched R5: 1.134/0.02374

SLC13A3 0.95 - - - - 0.950 - Mlig455_029498 {REF} {Length: 2725} {Pfam: Sodium:sulfate symporter transmembrane region [PF00939.21, score=288.8]; Citrate transporter [PF03600.18, score=115.2]} {Human: ENSG00000158296, SLC13A3, solute carrier family 13 member 3, [Score=405, Expect=1e-133]} {Mouse: ENSMUSG00000018459, Slc13a3, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, [Score=381, Expect=2e-124]; ENSMUSG00000001095, Slc13a2, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, [Score=366, Expect=1e-118]; ENSMUSG00000029700, Slc13a1, solute carrier family 13 (sodium/sulfate symporters), member 1, [Score=366, Expect=2e-118]; ENSMUSG00000029843, Slc13a4, solute carrier family 13 (sodium/sulfate symporters), member 4, [Score=364, Expect=2e-117]; ENSMUSG00000020805, Slc13a5, solute carrier family 13 (sodium-dependent citrate transporter), member 5, [Score=364, Expect=6e-118]} {Dmel: FBgn0036816, Indy, I'm not dead yet, [Score=276, Expect=2e-84]} {Celegans: WBGene00003517, nac-1, Sodium-dependent low-affinity dicarboxylate transporter 1, [Score=316, Expect=1e-99]} {Smed: dd_Smed_v6_12964_0_8, dd_Smed_v6_12964_0_8, [Score=360, Expect=6e-117]} {RNA1509_9551} {RNA1310_8761.2, RNA1509_9551} {RNA1509_9551, RNA815_3645}

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