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Results for MligTC455_44952

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_44952 726 15.13 Mlig455_011161

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.494

Region-enriched R5: 1.481/0.00145

 Mlig455_011161 {REF} {Length: 3053} {Celegans: WBGene00015646, mlt-10, [Score=172, Expect=4e-46]} {RNA1509_57962} {RNA1310_14000} {RNA815_26889}

Cumulative graph for MligTC455_44952

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.812 4.048 0.47881 1.00000
RegionR2 0.996 4.048 0.05514 0.28125
RegionR3 0.696 4.048 0.11059 0.57877
RegionR4 -0.849 4.048 0.09914 0.30581
RegionR5 1.481 4.048 0.00008 0.00145
RegionR6 0.518 4.048 0.25887 0.84644
RegionR7 -0.415 4.048 0.51424 1.00000
RegionR8 -1.615 4.048 0.07983 0.53728

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.241 4.048 0.87302 1.00000
RegenerationR2 0.451 4.048 0.27582 0.72058
RegenerationR3 0.381 4.048 0.41121 0.80933
RegenerationR4 0.831 4.048 0.09285 0.47509
RegenerationR5 -0.477 4.048 0.26405 0.69551
RegenerationR6 -0.214 4.048 0.67505 0.91136
RegenerationBL 0.89 4.048 0.13935 0.44495
RegenerationTP 2.078 4.048 0.00138 0.05741


Genes with expression patterns similar to MligTC455_44952

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_44952 726 15.13 Mlig455_011161

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.494

Region-enriched R5: 1.481/0.00145

 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_011161 {REF} {Length: 3053} {Celegans: WBGene00015646, mlt-10, [Score=172, Expect=4e-46]} {RNA1509_57962} {RNA1310_14000} {RNA815_26889}
2. MligTC455_49206 859 17.89 Mlig455_004480

Neo: -

Age: -

 1.762 - - 0.809 0.953 - - Mlig455_004480 {REF} {Length: 1143} {RNA1509_33030, RNA1509_49653} {RNA1310_49359.1, RNA1509_33030, RNA1509_49653} {RNA1509_33030, RNA1509_49653, RNA815_26981}
3. MligTC455_42659 2799 58.31 Mlig455_009046, Mlig455_058134

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.179

 PACSIN2 1.703 - - - 0.985 - 0.718

Mlig455_009046 {REF} {Length: 3055} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=54.6]; SH3 domain [PF00018.30, score=51.8]; Fes/CIP4, and EFC/F-BAR homology domain [PF00611.25, score=51.0]; Variant SH3 domain [PF07653.19, score=34.2]} {Human: ENSG00000100266, PACSIN2, protein kinase C and casein kinase substrate in neurons 2, [Score=325, Expect=5e-105]} {Mouse: ENSMUSG00000016664, Pacsin2, protein kinase C and casein kinase substrate in neurons 2, [RH, Score=335, Expect=2e-109]} {Dmel: FBgn0053094, Synd, Syndapin, [Score=285, Expect=4e-90]} {Celegans: WBGene00018467, sdpn-1, SynDaPiN (Synaptic dynamin binding protein) homolog, [Score=219, Expect=6e-65]} {Smed: dd_Smed_v6_7987_0_1, dd_Smed_v6_7987_0_1, [Score=351, Expect=1e-115]} {RNA1509_22117, RNA1509_37584} {RNA1310_9530, RNA1509_22117} {RNA1509_22117, RNA815_8193}

Mlig455_058134 {REF} {Length: 3083} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=54.5]; SH3 domain [PF00018.30, score=51.7]; Fes/CIP4, and EFC/F-BAR homology domain [PF00611.25, score=50.9]; Variant SH3 domain [PF07653.19, score=34.1]} {Human: ENSG00000100266, PACSIN2, protein kinase C and casein kinase substrate in neurons 2, [Score=322, Expect=1e-103]} {Mouse: ENSMUSG00000016664, Pacsin2, protein kinase C and casein kinase substrate in neurons 2, [Score=329, Expect=9e-107]} {Dmel: FBgn0053094, Synd, Syndapin, [Score=286, Expect=5e-90]} {Celegans: WBGene00018467, sdpn-1, SynDaPiN (Synaptic dynamin binding protein) homolog, [Score=187, Expect=7e-53]} {Smed: dd_Smed_v6_7987_0_1, dd_Smed_v6_7987_0_1, [Score=337, Expect=4e-110]} {RNA1509_37584} {RNA1310_9122.1} {RNA815_8193}
4. MligTC455_32784 1194 24.87 Mlig455_043430

Neo: -

Age: -

Region-enriched R7: 1.555/0.01708

 RCL1 1.694 - - - 0.951 0.743 - Mlig455_043430 {REF} {Length: 3933} {TRANSSPLICED} {Pfam: RNA 3'-terminal phosphate cyclase [PF01137.23, score=175.4]; Cyclic nucleotide-binding domain [PF00027.31, score=133.6]; RNA 3'-terminal phosphate cyclase (RTC), insert domain [PF05189.15, score=90.1]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=44.2]} {Human: ENSG00000120158, RCL1, RNA terminal phosphate cyclase like 1, [RH, Score=358, Expect=1e-116]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [RH, Score=380, Expect=1e-124]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=385, Expect=3e-127]} {Celegans: WBGene00022852, ZK1127.5, Probable RNA 3'-terminal phosphate cyclase-like protein, [RH, Score=299, Expect=3e-94]} {Smed: dd_Smed_v6_2902_0_1, dd_Smed_v6_2902_0_1, [Score=428, Expect=3e-144]} {RNA1509_16905} {RNA1310_10559.2} {RNA815_4244.1}
5. MligTC455_25335 470 9.79 Mlig455_067720

Neo: -

Age: -

 CDK16 1.668 0.711 - - - - 0.957 Mlig455_067720 {REF} {Length: 6652} {Pfam: Protein kinase domain [PF00069.27, score=227.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=110.9]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.2]; Haspin like kinase domain [PF12330.10, score=18.0]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=481, Expect=5e-163]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=462, Expect=2e-155]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=481, Expect=2e-163]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=460, Expect=6e-155]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=361, Expect=7e-117]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=410, Expect=1e-133]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=454, Expect=3e-151]} {RNA1509_47906} {RNA1310_5935} {RNA815_2428}
6. MligTC455_47600 263 5.48 Mlig455_031414

Neo: -

Age: -

Region-enriched R2: 2.961/0.01561

 NRXN1 0.967 - - - 0.967 - - Mlig455_031414 {REF} {Length: 4843} {Pfam: Laminin G domain [PF02210.26, score=235.7]; Laminin G domain [PF00054.25, score=191.1]; Syndecan domain [PF01034.22, score=26.0]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=22.3]; EGF-like domain [PF00008.29, score=19.4]} {Human: ENSG00000179915, NRXN1, neurexin 1, [RH, Score=379, Expect=3e-109]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=387, Expect=1e-112]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=313, Expect=5e-87]} {Celegans: WBGene00007799, nrx-1, NRX-1 beta isoform; NeuReXin related, [Score=179, Expect=2e-45]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [Score=349, Expect=9e-101]} {RNA1509_55888} {RNA1310_9438.1} {RNA815_24775.1}
7. MligTC455_51266 2459 51.22 Mlig455_048385, Mlig455_049087

Neo: -

Age: -

Region-enriched R7: 1.882/0.00099

 RAB3C 0.96 - - - 0.960 - -

Mlig455_048385 {REF} {Length: 3166} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=207.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=114.7]; ADP-ribosylation factor family [PF00025.23, score=53.9]; Signal recognition particle receptor beta subunit [PF09439.12, score=21.9]; 50S ribosome-binding GTPase [PF01926.25, score=20.9]; Elongation factor Tu GTP binding domain [PF00009.29, score=20.3]; Ferrous iron transport protein B [PF02421.20, score=18.9]; RsgA GTPase [PF03193.18, score=18.9]} {Human: ENSG00000152932, RAB3C, RAB3C, member RAS oncogene family, [RH, Score=355, Expect=1e-125]; ENSG00000169213, RAB3B, RAB3B, member RAS oncogene family, [RH, Score=346, Expect=3e-122]; ENSG00000105649, RAB3A, RAB3A, member RAS oncogene family, [RH, Score=345, Expect=8e-122]; ENSG00000105514, RAB3D, RAB3D, member RAS oncogene family, [RH, Score=338, Expect=3e-119]} {Mouse: ENSMUSG00000021700, Rab3c, RAB3C, member RAS oncogene family, [RH, Score=352, Expect=1e-124]; ENSMUSG00000031840, Rab3a, RAB3A, member RAS oncogene family, [RH, Score=345, Expect=4e-122]; ENSMUSG00000111277, Rab3a, RAB3A, member RAS onco family, [RH, Score=345, Expect=4e-122]; ENSMUSG00000019066, Rab3d, RAB3D, member RAS oncogene family, [RH, Score=342, Expect=1e-120]; ENSMUSG00000003411, Rab3b, RAB3B, member RAS oncogene family, [RH, Score=341, Expect=2e-120]} {Dmel: FBgn0005586, Rab3, [RH, Score=359, Expect=1e-127]} {Celegans: WBGene00004267, rab-3, Ras-related protein Rab-3, [RH, Score=353, Expect=3e-125]} {Smed: dd_Smed_v6_5920_0_1, dd_Smed_v6_5920_0_1, [RH, Score=345, Expect=2e-122]} {RNA1509_11395} {RNA1310_25880} {RNA815_16450}

Mlig455_049087 {REF} {Length: 3460} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=207.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=114.7]; ADP-ribosylation factor family [PF00025.23, score=53.9]; Signal recognition particle receptor beta subunit [PF09439.12, score=21.9]; 50S ribosome-binding GTPase [PF01926.25, score=20.9]; Elongation factor Tu GTP binding domain [PF00009.29, score=20.3]; Ferrous iron transport protein B [PF02421.20, score=18.9]; RsgA GTPase [PF03193.18, score=18.9]} {Human: ENSG00000152932, RAB3C, RAB3C, member RAS oncogene family, [RH, Score=355, Expect=1e-125]; ENSG00000169213, RAB3B, RAB3B, member RAS oncogene family, [RH, Score=346, Expect=3e-122]; ENSG00000105649, RAB3A, RAB3A, member RAS oncogene family, [RH, Score=345, Expect=8e-122]; ENSG00000105514, RAB3D, RAB3D, member RAS oncogene family, [RH, Score=338, Expect=3e-119]} {Mouse: ENSMUSG00000021700, Rab3c, RAB3C, member RAS oncogene family, [RH, Score=352, Expect=1e-124]; ENSMUSG00000031840, Rab3a, RAB3A, member RAS oncogene family, [RH, Score=345, Expect=4e-122]; ENSMUSG00000111277, Rab3a, RAB3A, member RAS onco family, [RH, Score=345, Expect=4e-122]; ENSMUSG00000019066, Rab3d, RAB3D, member RAS oncogene family, [RH, Score=342, Expect=1e-120]; ENSMUSG00000003411, Rab3b, RAB3B, member RAS oncogene family, [RH, Score=341, Expect=2e-120]} {Dmel: FBgn0005586, Rab3, [RH, Score=359, Expect=1e-127]} {Celegans: WBGene00004267, rab-3, Ras-related protein Rab-3, [RH, Score=353, Expect=3e-125]} {Smed: dd_Smed_v6_5920_0_1, dd_Smed_v6_5920_0_1, [RH, Score=345, Expect=2e-122]} {RNA1509_11395} {RNA1310_25880, RNA1509_11395} {RNA1509_11395, RNA815_16450}
8. MligTC455_35063 359 7.49 Mlig455_017090

Neo: -

Age: logFC(26M/2M)=-0.336

Region-enriched R2: 2.861/0.00814

 DNM1 0.956 - - - 0.956 - - Mlig455_017090 {REF} {Length: 4208} {Pfam: Dynamin central region [PF01031.22, score=334.5]; Dynamin family [PF00350.25, score=184.2]; Dynamin GTPase effector domain [PF02212.20, score=80.3]; PH domain [PF00169.31, score=37.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.3]} {Human: ENSG00000106976, DNM1, dynamin 1, [RH, Score=1101, Expect=0.0]; ENSG00000197959, DNM3, dynamin 3, [RH, Score=1094, Expect=0.0]; ENSG00000079805, DNM2, dynamin 2, [RH, Score=1075, Expect=0.0]} {Mouse: ENSMUSG00000026825, Dnm1, dynamin 1, [RH, Score=1102, Expect=0.0]; ENSMUSG00000040265, Dnm3, dynamin 3, [RH, Score=1089, Expect=0.0]; ENSMUSG00000033335, Dnm2, dynamin 2, [RH, Score=1074, Expect=0.0]} {Dmel: FBgn0003392, shi, shibire, [RH, Score=1074, Expect=0.0]} {Celegans: WBGene00001130, dyn-1, Dynamin, [RH, Score=984, Expect=0.0]} {Smed: dd_Smed_v6_6863_0_1, dd_Smed_v6_6863_0_1, [RH, Score=1068, Expect=0.0]} {RNA1509_31451, RNA1509_50695} {RNA1310_8903.1, RNA1509_31451, RNA1509_50695} {RNA1509_31451, RNA1509_50695, RNA815_1703.1}
9. MligTC455_53259 1211 25.23 Mlig455_000021, Mlig455_063726

Neo: -

Age: Down-Up-Down

Region-enriched R7: 2.967/0.00000

Regeneration-downregulated BL: -3.226

Regeneration-depleted BL: -3.226

 CALM2 0.952 - - - 0.952 - -

Mlig455_000021 {REF} {Length: 1568} {Pfam: EF hand [PF00036.34, score=104.3]; EF-hand domain pair [PF13499.8, score=101.0]; EF-hand domain [PF13405.8, score=85.6]; EF-hand domain pair [PF13833.8, score=69.9]; EF hand [PF13202.8, score=68.0]; EF-hand domain [PF14658.8, score=45.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=26.1]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=181, Expect=6e-58]; ENSG00000178363, CALML3, calmodulin like 3, [Score=177, Expect=6e-57]; ENSG00000160014, CALM3, calmodulin 3, [Score=176, Expect=1e-56]; ENSG00000198668, CALM1, calmodulin 1, [Score=176, Expect=1e-56]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=180, Expect=2e-58]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=178, Expect=6e-57]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=176, Expect=7e-57]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=176, Expect=7e-57]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=175, Expect=2e-56]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=174, Expect=3e-56]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=174, Expect=2e-56]} {RNA1509_7324} {RNA1310_27659.2, RNA1509_7324} {RNA1509_7324, RNA815_12079.1}

Mlig455_063726 {REF} {Length: 1571} {Pfam: EF hand [PF00036.34, score=104.3]; EF-hand domain pair [PF13499.8, score=101.0]; EF-hand domain [PF13405.8, score=85.6]; EF-hand domain pair [PF13833.8, score=69.9]; EF hand [PF13202.8, score=68.0]; EF-hand domain [PF14658.8, score=45.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=26.1]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=181, Expect=6e-58]; ENSG00000178363, CALML3, calmodulin like 3, [Score=177, Expect=6e-57]; ENSG00000160014, CALM3, calmodulin 3, [Score=176, Expect=1e-56]; ENSG00000198668, CALM1, calmodulin 1, [Score=176, Expect=1e-56]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=180, Expect=2e-58]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=178, Expect=6e-57]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=176, Expect=7e-57]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=176, Expect=7e-57]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=175, Expect=2e-56]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=174, Expect=3e-56]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=174, Expect=2e-56]} {RNA1509_7324} {RNA1310_27659.2} {RNA815_12079.1}

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