M. lignano Tomo-Seq
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Results for MligTC455_45516

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45516 2861 59.60 Mlig455_002293

Neo: Irradiation

Age: logFC(26M/2M)=0.238

Regeneration-enriched BL: 1.277
Regeneration-enriched R6: 1.154

 SRSF4 Mlig455_002293 {REF} {Length: 1828} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=99.1]; RNA binding motif [PF08777.13, score=33.1]} {Human: ENSG00000116350, SRSF4, serine and arginine rich splicing factor 4, [RH, Score=193, Expect=6e-57]} {Mouse: ENSMUSG00000028911, Srsf4, serine/arginine-rich splicing factor 4, [RH, Score=197, Expect=2e-58]} {Dmel: FBgn0004587, B52, [RH, Score=182, Expect=1e-54]} {Celegans: WBGene00004699, rsp-2, Probable splicing factor, arginine/serine-rich 2, [RH, Score=141, Expect=9e-40]} {Smed: dd_Smed_v6_3431_0_1, dd_Smed_v6_3431_0_1, [RH, Score=186, Expect=3e-56]} {RNA1509_22914} {RNA1310_8234, RNA1509_22914} {RNA1509_22914, RNA815_2822}

Cumulative graph for MligTC455_45516

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.04 5.97 0.94675 1.00000
RegionR2 -0.525 5.97 0.08709 0.36275
RegionR3 0.027 5.97 0.91269 1.00000
RegionR4 0.516 5.97 0.06428 0.22840
RegionR5 0.669 5.97 0.00237 0.01978
RegionR6 -0.048 5.97 0.84955 1.00000
RegionR7 -0.126 5.97 0.69389 1.00000
RegionR8 -0.552 5.97 0.19420 0.78912

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.446 5.97 0.53067 1.00000
RegenerationR2 0.125 5.97 0.65320 0.93781
RegenerationR3 0.402 5.97 0.16695 0.60142
RegenerationR4 0.328 5.97 0.25742 0.70533
RegenerationR5 0.658 5.97 0.01365 0.20404
RegenerationR6 1.154 5.97 0.00006 0.00618
RegenerationBL 1.277 5.97 0.00001 0.00083
RegenerationTP 0.267 5.97 0.46721 0.87874


Genes with expression patterns similar to MligTC455_45516

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45516 2861 59.6 Mlig455_002293

Neo: Irradiation

Age: logFC(26M/2M)=0.238

Regeneration-enriched BL: 1.277
Regeneration-enriched R6: 1.154

 SRSF4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_002293 {REF} {Length: 1828} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=99.1]; RNA binding motif [PF08777.13, score=33.1]} {Human: ENSG00000116350, SRSF4, serine and arginine rich splicing factor 4, [RH, Score=193, Expect=6e-57]} {Mouse: ENSMUSG00000028911, Srsf4, serine/arginine-rich splicing factor 4, [RH, Score=197, Expect=2e-58]} {Dmel: FBgn0004587, B52, [RH, Score=182, Expect=1e-54]} {Celegans: WBGene00004699, rsp-2, Probable splicing factor, arginine/serine-rich 2, [RH, Score=141, Expect=9e-40]} {Smed: dd_Smed_v6_3431_0_1, dd_Smed_v6_3431_0_1, [RH, Score=186, Expect=3e-56]} {RNA1509_22914} {RNA1310_8234, RNA1509_22914} {RNA1509_22914, RNA815_2822}
2. MligTC455_45515 5651 117.72 Mlig455_002150, Mlig455_002249

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.276

Regeneration-enriched BL: 1.266
Regeneration-enriched R6: 1.095

 SRSF4 5.975 0.997 0.990 0.999 0.994 0.998 0.997

Mlig455_002150 {REF} {Length: 1581} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=100.2]; RNA binding motif [PF08777.13, score=34.1]} {Human: ENSG00000116350, SRSF4, serine and arginine rich splicing factor 4, [RH, Score=188, Expect=3e-57]} {Mouse: ENSMUSG00000028911, Srsf4, serine/arginine-rich splicing factor 4, [RH, Score=190, Expect=4e-57]} {Dmel: FBgn0004587, B52, [RH, Score=180, Expect=1e-54]} {Celegans: WBGene00004699, rsp-2, Probable splicing factor, arginine/serine-rich 2, [RH, Score=148, Expect=4e-43]} {Smed: dd_Smed_v6_3431_0_1, dd_Smed_v6_3431_0_1, [RH, Score=183, Expect=2e-56]} {RNA1509_22914} {RNA1310_2260.1} {RNA815_2822}

Mlig455_002249 {REF} {Length: 1685} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=99.7]; RNA binding motif [PF08777.13, score=33.6]} {Human: ENSG00000116350, SRSF4, serine and arginine rich splicing factor 4, [RH, Score=191, Expect=1e-57]} {Mouse: ENSMUSG00000028911, Srsf4, serine/arginine-rich splicing factor 4, [RH, Score=194, Expect=8e-58]} {Dmel: FBgn0004587, B52, [RH, Score=181, Expect=1e-54]} {Celegans: WBGene00004699, rsp-2, Probable splicing factor, arginine/serine-rich 2, [RH, Score=131, Expect=3e-36]} {Smed: dd_Smed_v6_3431_0_1, dd_Smed_v6_3431_0_1, [RH, Score=185, Expect=2e-56]} {RNA1509_22914} {RNA1310_2260.1} {RNA815_2822}
3. MligTC455_40047 1969 41.02 Mlig455_061883

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.325/0.00004
Region-enriched R4: 1.267/0.00239

Regeneration-upregulated BL: 1.463

Regeneration-enriched BL: 1.463

 ARPP19 1.666 - - - - 0.712 0.954 Mlig455_061883 {REF} {Length: 1192} {TRANSSPLICED} {Pfam: cAMP-regulated phosphoprotein/endosulfine conserved region [PF04667.19, score=40.3]} {Human: ENSG00000128989, ARPP19, cAMP regulated phosphoprotein 19, [RH, Score=85.5, Expect=6e-22]; ENSG00000143420, ENSA, endosulfine alpha, [RH, Score=83.6, Expect=4e-21]} {Mouse: ENSMUSG00000007656, Arpp19, cAMP-regulated phosphoprotein 19, [RH, Score=85.1, Expect=4e-22]; ENSMUSG00000038619, Ensa, endosulfine alpha, [RH, Score=84.3, Expect=1e-21]} {Dmel: FBgn0061515, endos, endosulfine, [RH, Score=71.2, Expect=1e-16]} {Smed: dd_Smed_v6_4126_0_2, dd_Smed_v6_4126_0_2, [RH, Score=99.0, Expect=1e-27]} {RNA1509_17883, RNA1509_26901, RNA1509_5887, RNA1509_7335} {RNA1310_27715, RNA1509_17883, RNA1509_26901, RNA1509_5887, RNA1509_7335} {RNA1509_17883, RNA1509_26901, RNA1509_5887, RNA1509_7335, RNA815_12892.1}
4. MligTC455_43935 7749 161.43 Mlig455_045402

Neo: -

Age: logFC(26M/2M)=0.435

Region-enriched R6: 1.517/0.00198

 METTL27 0.971 - - - - 0.971 - Mlig455_045402 {REF} {Length: 1176} {Pfam: Methyltransferase domain [PF13649.8, score=26.4]; Methyltransferase small domain [PF05175.16, score=21.7]; Methyltransferase domain [PF13489.8, score=20.0]} {Human: ENSG00000165171, METTL27, methyltransferase like 27, [Score=78.6, Expect=1e-16]} {Mouse: ENSMUSG00000040557, Mettl27, methyltransferase like 27, [Score=80.1, Expect=2e-17]} {Smed: dd_Smed_v6_5408_0_1, dd_Smed_v6_5408_0_1, [RH, Score=154, Expect=2e-46]} {RNA1509_23136} {RNA1310_39479.1} {RNA815_18819.1}
5. MligTC455_31180 2635 54.89 Mlig455_051867

Neo: -

Age: logFC(26M/2M)=0.298

Region-enriched R6: 1.875/0.00081
Region-enriched R5: 1.564/0.00104
Region-enriched R4: 1.318/0.04234

 ANPEP 0.953 - - - - 0.953 - Mlig455_051867 {REF} {Length: 4944} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=264.9]; Peptidase family M1 domain [PF01433.22, score=166.1]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=377, Expect=2e-118]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=384, Expect=3e-121]} {Dmel: FBgn0052473, CG32473, [Score=344, Expect=7e-107]} {Celegans: WBGene00009865, F49B2.6, Aminopeptidase, [Score=282, Expect=7e-83]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=393, Expect=2e-124]} {RNA1509_1573} {RNA1310_1662.1, RNA1509_1573} {RNA1509_1573, RNA815_759.1}

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