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Results for MligTC455_45593

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45593 620 12.91 Mlig455_071089

Neo: -

Age: -

VCP Mlig455_071089 {REF} {Length: 3261} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=321.1]; AAA+ lid domain [PF17862.3, score=84.4]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=76.4]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=51.5]; AAA ATPase domain [PF13191.8, score=46.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=42.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=41.0]; AAA domain [PF13671.8, score=40.8]; Vps4 C terminal oligomerisation domain [PF09336.12, score=38.5]; AAA domain [PF13401.8, score=37.9]; TIP49 P-loop domain [PF06068.15, score=34.6]; AAA domain [PF13238.8, score=32.0]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=30.4]; RNA helicase [PF00910.24, score=29.8]; AAA domain [PF13173.8, score=29.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=28.7]; IstB-like ATP binding protein [PF01695.19, score=27.6]; ABC transporter [PF00005.29, score=27.3]; AAA domain [PF13521.8, score=27.1]; P-loop containing dynein motor region [PF12775.9, score=25.9]; AAA domain [PF13207.8, score=24.7]; Parvovirus non-structural protein NS1 [PF01057.19, score=24.5]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.0]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=22.8]; Bacterial dnaA protein [PF00308.20, score=22.7]; ATPase domain predominantly from Archaea [PF01637.20, score=22.4]; AAA domain [PF13481.8, score=22.4]; KaiC [PF06745.15, score=22.1]; Sigma-54 interaction domain [PF00158.28, score=21.5]; Zeta toxin [PF06414.14, score=20.9]; AAA domain [PF13479.8, score=20.3]; Type III restriction enzyme, res subunit [PF04851.17, score=20.1]; NACHT domain [PF05729.14, score=19.6]; Sigma-54 interaction domain [PF14532.8, score=19.1]; NB-ARC domain [PF00931.24, score=19.0]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=18.5]; PhoH-like protein [PF02562.18, score=18.4]; Protein of unknown function (DUF815) [PF05673.15, score=18.4]} {Human: ENSG00000165280, VCP, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Mouse: ENSMUSG00000028452, Vcp, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Dmel: FBgn0261014, TER94, [RH, Score=1257, Expect=0.0]} {Celegans: WBGene00008053, cdc-48.2, Transitional endoplasmic reticulum ATPase homolog 2, [RH, Score=1214, Expect=0.0]} {Smed: dd_Smed_v6_482_0_1, dd_Smed_v6_482_0_1, [RH, Score=1300, Expect=0.0]} {RNA1509_10842} {RNA1310_14598.1} {RNA815_1672.1}

Cumulative graph for MligTC455_45593

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.766 4.071 0.38952 1.00000
RegionR2 0.309 4.071 0.63914 0.97746
RegionR3 0.08 4.071 0.88458 1.00000
RegionR4 0.534 4.071 0.38069 0.70524
RegionR5 0.752 4.071 0.13222 0.37024
RegionR6 0.738 4.071 0.18380 0.74836
RegionR7 -0.49 4.071 0.59010 1.00000
RegionR8 -0.157 4.071 0.88756 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 2.128 4.071 0.35797 1.00000
RegenerationR2 0.861 4.071 0.06101 0.40595
RegenerationR3 1.64 4.071 0.00251 0.08710
RegenerationR4 1.509 4.071 0.00466 0.09545
RegenerationR5 1.404 4.071 0.00281 0.09323
RegenerationR6 1.625 4.071 0.00127 0.03931
RegenerationBL 1.404 4.071 0.02309 0.16643
RegenerationTP 1.385 4.071 0.06790 0.41912


Genes with expression patterns similar to MligTC455_45593

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45593 620 12.91 Mlig455_071089

Neo: -

Age: -

VCP 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_071089 {REF} {Length: 3261} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=321.1]; AAA+ lid domain [PF17862.3, score=84.4]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=76.4]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=51.5]; AAA ATPase domain [PF13191.8, score=46.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=42.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=41.0]; AAA domain [PF13671.8, score=40.8]; Vps4 C terminal oligomerisation domain [PF09336.12, score=38.5]; AAA domain [PF13401.8, score=37.9]; TIP49 P-loop domain [PF06068.15, score=34.6]; AAA domain [PF13238.8, score=32.0]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=30.4]; RNA helicase [PF00910.24, score=29.8]; AAA domain [PF13173.8, score=29.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=28.7]; IstB-like ATP binding protein [PF01695.19, score=27.6]; ABC transporter [PF00005.29, score=27.3]; AAA domain [PF13521.8, score=27.1]; P-loop containing dynein motor region [PF12775.9, score=25.9]; AAA domain [PF13207.8, score=24.7]; Parvovirus non-structural protein NS1 [PF01057.19, score=24.5]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.0]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=22.8]; Bacterial dnaA protein [PF00308.20, score=22.7]; ATPase domain predominantly from Archaea [PF01637.20, score=22.4]; AAA domain [PF13481.8, score=22.4]; KaiC [PF06745.15, score=22.1]; Sigma-54 interaction domain [PF00158.28, score=21.5]; Zeta toxin [PF06414.14, score=20.9]; AAA domain [PF13479.8, score=20.3]; Type III restriction enzyme, res subunit [PF04851.17, score=20.1]; NACHT domain [PF05729.14, score=19.6]; Sigma-54 interaction domain [PF14532.8, score=19.1]; NB-ARC domain [PF00931.24, score=19.0]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=18.5]; PhoH-like protein [PF02562.18, score=18.4]; Protein of unknown function (DUF815) [PF05673.15, score=18.4]} {Human: ENSG00000165280, VCP, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Mouse: ENSMUSG00000028452, Vcp, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Dmel: FBgn0261014, TER94, [RH, Score=1257, Expect=0.0]} {Celegans: WBGene00008053, cdc-48.2, Transitional endoplasmic reticulum ATPase homolog 2, [RH, Score=1214, Expect=0.0]} {Smed: dd_Smed_v6_482_0_1, dd_Smed_v6_482_0_1, [RH, Score=1300, Expect=0.0]} {RNA1509_10842} {RNA1310_14598.1} {RNA815_1672.1}
2. MligTC455_45262 189 3.93 Mlig455_007101

Neo: -

Age: -

1.857 - - - 0.894 0.963 - Mlig455_007101 {REF} {Length: 2592} {Dmel: FBgn0053519, Unc-89, [Score=50.8, Expect=4e-06]} {Smed: dd_Smed_v6_5091_0_1, dd_Smed_v6_5091_0_1, [Score=137, Expect=2e-36]} {RNA1509_54868} {RNA1310_9306} {RNA815_2941.1}
3. MligTC455_24698 664 13.84 Mlig455_002176

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.133/0.00000
Region-enriched R4: 1.095/0.04769

1.779 - - - 0.810 0.969 - Mlig455_002176 {REF} {Length: 1826} {TRANSSPLICED} {RNA1509_10156} {RNA1310_5607} {RNA815_1167}
4. MligTC455_23168 1390 28.95 Mlig455_010328, Mlig455_065663

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.082/0.00159

OGG1 1.715 - - - 0.951 0.764 -

Mlig455_010328 {REF} {Length: 226} {NoTransDecoderORF} {RNA1509_8363} {RNA1310_3839} {RNA815_1115}

Mlig455_065663 {REF} {Length: 4418} {Pfam: Microtubule-associated protein Bicaudal-D [PF09730.11, score=354.3]; 8-oxoguanine DNA glycosylase, N-terminal domain [PF07934.14, score=77.4]; HhH-GPD superfamily base excision DNA repair protein [PF00730.27, score=53.4]} {Human: ENSG00000114026, OGG1, 8-oxoguanine DNA glycosylase, [RH, Score=253, Expect=8e-75]} {Mouse: ENSMUSG00000030271, Ogg1, 8-oxoguanine DNA-glycosylase 1, [RH, Score=249, Expect=2e-73]} {Dmel: FBgn0000183, BicD, Bicaudal D, [RH, Score=211, Expect=2e-56]} {Celegans: WBGene00016611, bicd-1, BICaudal D (Drosophila) homolog, [RH, Score=145, Expect=2e-35]} {Smed: dd_Smed_v6_758_0_1, dd_Smed_v6_758_0_1, [RH, Score=328, Expect=2e-95]} {RNA1509_12040, RNA1509_8363} {RNA1310_3839, RNA1509_12040} {RNA1509_12040, RNA815_7397}
5. MligTC455_45333 5039 104.98 Mlig455_024662, Mlig455_048643, Mlig455_068867

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.566/0.00006
Region-enriched R3: 1.419/0.00002

LIPA 1.681 - - - 0.728 0.953 -

Mlig455_024662 {REF} {Length: 2228} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_048643 {REF} {Length: 2232} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_068867 {REF} {Length: 4154} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}
6. MligTC455_50645 44 0.91 Mlig455_036533

Neo: -

Age: -

SCYL1 0.965 - - - - 0.965 - Mlig455_036533 {REF} {Length: 4260} {TRANSSPLICED} {Pfam: HEAT repeat [PF02985.24, score=41.4]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=37.1]; HEAT repeats [PF13646.8, score=32.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=25.7]; Protein kinase domain [PF00069.27, score=23.0]} {Human: ENSG00000142186, SCYL1, SCY1 like pseudokinase 1, [RH, Score=447, Expect=7e-145]} {Mouse: ENSMUSG00000024941, Scyl1, SCY1-like 1 (S. cerevisiae), [RH, Score=441, Expect=6e-143]} {Dmel: FBgn0260990, yata, [RH, Score=516, Expect=4e-171]} {Celegans: WBGene00012337, W07G4.3, [RH, Score=404, Expect=6e-129]} {Smed: dd_Smed_v6_3470_0_1, dd_Smed_v6_3470_0_1, [RH, Score=460, Expect=5e-152]} {RNA1509_21531, RNA1509_23084, RNA1509_58473} {RNA1310_4140, RNA1509_21531, RNA1509_23084, RNA1509_58473} {RNA1509_21531, RNA1509_23084, RNA1509_58473, RNA815_4060}
7. MligTC455_51802 2189 45.59 Mlig455_011067

Neo: -

Age: logFC(26M/2M)=0.199

KPNA4 0.957 - - - - 0.957 - Mlig455_011067 {REF} {Length: 3382} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=281.5]; Atypical Arm repeat [PF16186.7, score=80.0]; Importin beta binding domain [PF01749.22, score=75.4]; HEAT-like repeat [PF13513.8, score=71.9]; HEAT repeats [PF13646.8, score=65.4]; HEAT repeat [PF02985.24, score=56.5]; Adaptin N terminal region [PF01602.22, score=27.0]; V-ATPase subunit H [PF11698.10, score=26.9]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=25.5]; Armadillo-like [PF04826.15, score=25.2]; Parkin co-regulated protein [PF10274.11, score=19.9]; V-ATPase subunit H [PF03224.16, score=18.1]} {Human: ENSG00000186432, KPNA4, karyopherin subunit alpha 4, [RH, Score=701, Expect=0.0]; ENSG00000102753, KPNA3, karyopherin subunit alpha 3, [RH, Score=696, Expect=0.0]} {Mouse: ENSMUSG00000027782, Kpna4, karyopherin (importin) alpha 4, [RH, Score=701, Expect=0.0]; ENSMUSG00000021929, Kpna3, karyopherin (importin) alpha 3, [RH, Score=696, Expect=0.0]} {Dmel: FBgn0027338, Kap-alpha3, karyopherin alpha3, [RH, Score=646, Expect=0.0]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [RH, Score=613, Expect=0.0]} {Smed: dd_Smed_v6_590_0_1, dd_Smed_v6_590_0_1, [RH, Score=704, Expect=0.0]} {RNA1509_13740, RNA1509_1383} {RNA1310_3813.1, RNA1509_13740, RNA1509_1383} {RNA1509_13740, RNA1509_1383, RNA815_7735}
8. MligTC455_39843 434 9.04 Mlig455_031862

Neo: -

Age: logFC(26M/2M)=0.323

Region-enriched R5: 3.071/0.00013

0.955 - - - 0.955 - - Mlig455_031862 {REF} {Length: 3865} {Smed: dd_Smed_v6_11504_0_1, dd_Smed_v6_11504_0_1, [Score=160, Expect=1e-44]} {RNA1509_38226} {RNA1310_9352.1, RNA1509_38226} {RNA1509_38226, RNA815_18353}
9. MligTC455_49944 108 2.25 Mlig455_067437

Neo: -

Age: logFC(26M/2M)=-0.477

Region-enriched R4: 2.865/0.02691

GSTP1 0.954 - - - - 0.954 - Mlig455_067437 {REF} {Length: 1036} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=66.1]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=21.1]} {Human: ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=66.2, Expect=9e-13]} {Mouse: ENSMUSG00000097663, Gstp3, glutathione S-transferase pi 3, [Score=56.2, Expect=3e-09]; ENSMUSG00000058216, Gstp3, glutathione S-transferase pi 3, [Score=56.2, Expect=3e-09]; ENSMUSG00000068762, Gstm6, glutathione S-transferase, mu 6, [Score=55.8, Expect=4e-09]} {Celegans: WBGene00001762, gst-14, Glutathione S-Transferase, [Score=64.7, Expect=1e-12]} {RNA1509_34951} {RNA1310_12535} {RNA815_15521.1}

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