Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_45593 | 620 | 12.91 | Mlig455_071089 | Neo: - Age: - |
VCP | Mlig455_071089 {REF} {Length: 3261} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=321.1]; AAA+ lid domain [PF17862.3, score=84.4]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=76.4]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=51.5]; AAA ATPase domain [PF13191.8, score=46.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=42.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=41.0]; AAA domain [PF13671.8, score=40.8]; Vps4 C terminal oligomerisation domain [PF09336.12, score=38.5]; AAA domain [PF13401.8, score=37.9]; TIP49 P-loop domain [PF06068.15, score=34.6]; AAA domain [PF13238.8, score=32.0]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=30.4]; RNA helicase [PF00910.24, score=29.8]; AAA domain [PF13173.8, score=29.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=28.7]; IstB-like ATP binding protein [PF01695.19, score=27.6]; ABC transporter [PF00005.29, score=27.3]; AAA domain [PF13521.8, score=27.1]; P-loop containing dynein motor region [PF12775.9, score=25.9]; AAA domain [PF13207.8, score=24.7]; Parvovirus non-structural protein NS1 [PF01057.19, score=24.5]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.0]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=22.8]; Bacterial dnaA protein [PF00308.20, score=22.7]; ATPase domain predominantly from Archaea [PF01637.20, score=22.4]; AAA domain [PF13481.8, score=22.4]; KaiC [PF06745.15, score=22.1]; Sigma-54 interaction domain [PF00158.28, score=21.5]; Zeta toxin [PF06414.14, score=20.9]; AAA domain [PF13479.8, score=20.3]; Type III restriction enzyme, res subunit [PF04851.17, score=20.1]; NACHT domain [PF05729.14, score=19.6]; Sigma-54 interaction domain [PF14532.8, score=19.1]; NB-ARC domain [PF00931.24, score=19.0]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=18.5]; PhoH-like protein [PF02562.18, score=18.4]; Protein of unknown function (DUF815) [PF05673.15, score=18.4]} {Human: ENSG00000165280, VCP, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Mouse: ENSMUSG00000028452, Vcp, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Dmel: FBgn0261014, TER94, [RH, Score=1257, Expect=0.0]} {Celegans: WBGene00008053, cdc-48.2, Transitional endoplasmic reticulum ATPase homolog 2, [RH, Score=1214, Expect=0.0]} {Smed: dd_Smed_v6_482_0_1, dd_Smed_v6_482_0_1, [RH, Score=1300, Expect=0.0]} {RNA1509_10842} {RNA1310_14598.1} {RNA815_1672.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.766 | 4.071 | 0.38952 | 1.00000 | |
RegionR2 | 0.309 | 4.071 | 0.63914 | 0.97746 | |
RegionR3 | 0.08 | 4.071 | 0.88458 | 1.00000 | |
RegionR4 | 0.534 | 4.071 | 0.38069 | 0.70524 | |
RegionR5 | 0.752 | 4.071 | 0.13222 | 0.37024 | |
RegionR6 | 0.738 | 4.071 | 0.18380 | 0.74836 | |
RegionR7 | -0.49 | 4.071 | 0.59010 | 1.00000 | |
RegionR8 | -0.157 | 4.071 | 0.88756 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 2.128 | 4.071 | 0.35797 | 1.00000 | |
RegenerationR2 | 0.861 | 4.071 | 0.06101 | 0.40595 | |
RegenerationR3 | 1.64 | 4.071 | 0.00251 | 0.08710 | |
RegenerationR4 | 1.509 | 4.071 | 0.00466 | 0.09545 | |
RegenerationR5 | 1.404 | 4.071 | 0.00281 | 0.09323 | |
RegenerationR6 | 1.625 | 4.071 | 0.00127 | 0.03931 | |
RegenerationBL | 1.404 | 4.071 | 0.02309 | 0.16643 | |
RegenerationTP | 1.385 | 4.071 | 0.06790 | 0.41912 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_45593 | 620 | 12.91 | Mlig455_071089 | Neo: - Age: - |
VCP | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_071089 {REF} {Length: 3261} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=321.1]; AAA+ lid domain [PF17862.3, score=84.4]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=76.4]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=51.5]; AAA ATPase domain [PF13191.8, score=46.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=42.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=41.0]; AAA domain [PF13671.8, score=40.8]; Vps4 C terminal oligomerisation domain [PF09336.12, score=38.5]; AAA domain [PF13401.8, score=37.9]; TIP49 P-loop domain [PF06068.15, score=34.6]; AAA domain [PF13238.8, score=32.0]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=30.4]; RNA helicase [PF00910.24, score=29.8]; AAA domain [PF13173.8, score=29.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=28.7]; IstB-like ATP binding protein [PF01695.19, score=27.6]; ABC transporter [PF00005.29, score=27.3]; AAA domain [PF13521.8, score=27.1]; P-loop containing dynein motor region [PF12775.9, score=25.9]; AAA domain [PF13207.8, score=24.7]; Parvovirus non-structural protein NS1 [PF01057.19, score=24.5]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.0]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=22.8]; Bacterial dnaA protein [PF00308.20, score=22.7]; ATPase domain predominantly from Archaea [PF01637.20, score=22.4]; AAA domain [PF13481.8, score=22.4]; KaiC [PF06745.15, score=22.1]; Sigma-54 interaction domain [PF00158.28, score=21.5]; Zeta toxin [PF06414.14, score=20.9]; AAA domain [PF13479.8, score=20.3]; Type III restriction enzyme, res subunit [PF04851.17, score=20.1]; NACHT domain [PF05729.14, score=19.6]; Sigma-54 interaction domain [PF14532.8, score=19.1]; NB-ARC domain [PF00931.24, score=19.0]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=18.5]; PhoH-like protein [PF02562.18, score=18.4]; Protein of unknown function (DUF815) [PF05673.15, score=18.4]} {Human: ENSG00000165280, VCP, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Mouse: ENSMUSG00000028452, Vcp, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Dmel: FBgn0261014, TER94, [RH, Score=1257, Expect=0.0]} {Celegans: WBGene00008053, cdc-48.2, Transitional endoplasmic reticulum ATPase homolog 2, [RH, Score=1214, Expect=0.0]} {Smed: dd_Smed_v6_482_0_1, dd_Smed_v6_482_0_1, [RH, Score=1300, Expect=0.0]} {RNA1509_10842} {RNA1310_14598.1} {RNA815_1672.1} |
2. | MligTC455_45262 | 189 | 3.93 | Mlig455_007101 | Neo: - Age: - |
1.857 | - | - | - | 0.894 | 0.963 | - | Mlig455_007101 {REF} {Length: 2592} {Dmel: FBgn0053519, Unc-89, [Score=50.8, Expect=4e-06]} {Smed: dd_Smed_v6_5091_0_1, dd_Smed_v6_5091_0_1, [Score=137, Expect=2e-36]} {RNA1509_54868} {RNA1310_9306} {RNA815_2941.1} | |
3. | MligTC455_24698 | 664 | 13.84 | Mlig455_002176 | Neo: - Age: Up-Down-Up Region-enriched R3: 2.133/0.00000 |
1.779 | - | - | - | 0.810 | 0.969 | - | Mlig455_002176 {REF} {Length: 1826} {TRANSSPLICED} {RNA1509_10156} {RNA1310_5607} {RNA815_1167} | |
4. | MligTC455_23168 | 1390 | 28.95 | Mlig455_010328, Mlig455_065663 | Neo: Neoblast, stringent Age: - Region-enriched R5: 1.082/0.00159 |
OGG1 | 1.715 | - | - | - | 0.951 | 0.764 | - | Mlig455_010328 {REF} {Length: 226} {NoTransDecoderORF} {RNA1509_8363} {RNA1310_3839} {RNA815_1115} Mlig455_065663 {REF} {Length: 4418} {Pfam: Microtubule-associated protein Bicaudal-D [PF09730.11, score=354.3]; 8-oxoguanine DNA glycosylase, N-terminal domain [PF07934.14, score=77.4]; HhH-GPD superfamily base excision DNA repair protein [PF00730.27, score=53.4]} {Human: ENSG00000114026, OGG1, 8-oxoguanine DNA glycosylase, [RH, Score=253, Expect=8e-75]} {Mouse: ENSMUSG00000030271, Ogg1, 8-oxoguanine DNA-glycosylase 1, [RH, Score=249, Expect=2e-73]} {Dmel: FBgn0000183, BicD, Bicaudal D, [RH, Score=211, Expect=2e-56]} {Celegans: WBGene00016611, bicd-1, BICaudal D (Drosophila) homolog, [RH, Score=145, Expect=2e-35]} {Smed: dd_Smed_v6_758_0_1, dd_Smed_v6_758_0_1, [RH, Score=328, Expect=2e-95]} {RNA1509_12040, RNA1509_8363} {RNA1310_3839, RNA1509_12040} {RNA1509_12040, RNA815_7397} |
5. | MligTC455_45333 | 5039 | 104.98 | Mlig455_024662, Mlig455_048643, Mlig455_068867 | Neo: - Age: Down-Up-Up Region-enriched R4: 1.566/0.00006 |
LIPA | 1.681 | - | - | - | 0.728 | 0.953 | - | Mlig455_024662 {REF} {Length: 2228} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697} Mlig455_048643 {REF} {Length: 2232} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697} Mlig455_068867 {REF} {Length: 4154} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697} |
6. | MligTC455_50645 | 44 | 0.91 | Mlig455_036533 | Neo: - Age: - |
SCYL1 | 0.965 | - | - | - | - | 0.965 | - | Mlig455_036533 {REF} {Length: 4260} {TRANSSPLICED} {Pfam: HEAT repeat [PF02985.24, score=41.4]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=37.1]; HEAT repeats [PF13646.8, score=32.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=25.7]; Protein kinase domain [PF00069.27, score=23.0]} {Human: ENSG00000142186, SCYL1, SCY1 like pseudokinase 1, [RH, Score=447, Expect=7e-145]} {Mouse: ENSMUSG00000024941, Scyl1, SCY1-like 1 (S. cerevisiae), [RH, Score=441, Expect=6e-143]} {Dmel: FBgn0260990, yata, [RH, Score=516, Expect=4e-171]} {Celegans: WBGene00012337, W07G4.3, [RH, Score=404, Expect=6e-129]} {Smed: dd_Smed_v6_3470_0_1, dd_Smed_v6_3470_0_1, [RH, Score=460, Expect=5e-152]} {RNA1509_21531, RNA1509_23084, RNA1509_58473} {RNA1310_4140, RNA1509_21531, RNA1509_23084, RNA1509_58473} {RNA1509_21531, RNA1509_23084, RNA1509_58473, RNA815_4060} |
7. | MligTC455_51802 | 2189 | 45.59 | Mlig455_011067 | Neo: - Age: logFC(26M/2M)=0.199 |
KPNA4 | 0.957 | - | - | - | - | 0.957 | - | Mlig455_011067 {REF} {Length: 3382} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=281.5]; Atypical Arm repeat [PF16186.7, score=80.0]; Importin beta binding domain [PF01749.22, score=75.4]; HEAT-like repeat [PF13513.8, score=71.9]; HEAT repeats [PF13646.8, score=65.4]; HEAT repeat [PF02985.24, score=56.5]; Adaptin N terminal region [PF01602.22, score=27.0]; V-ATPase subunit H [PF11698.10, score=26.9]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=25.5]; Armadillo-like [PF04826.15, score=25.2]; Parkin co-regulated protein [PF10274.11, score=19.9]; V-ATPase subunit H [PF03224.16, score=18.1]} {Human: ENSG00000186432, KPNA4, karyopherin subunit alpha 4, [RH, Score=701, Expect=0.0]; ENSG00000102753, KPNA3, karyopherin subunit alpha 3, [RH, Score=696, Expect=0.0]} {Mouse: ENSMUSG00000027782, Kpna4, karyopherin (importin) alpha 4, [RH, Score=701, Expect=0.0]; ENSMUSG00000021929, Kpna3, karyopherin (importin) alpha 3, [RH, Score=696, Expect=0.0]} {Dmel: FBgn0027338, Kap-alpha3, karyopherin alpha3, [RH, Score=646, Expect=0.0]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [RH, Score=613, Expect=0.0]} {Smed: dd_Smed_v6_590_0_1, dd_Smed_v6_590_0_1, [RH, Score=704, Expect=0.0]} {RNA1509_13740, RNA1509_1383} {RNA1310_3813.1, RNA1509_13740, RNA1509_1383} {RNA1509_13740, RNA1509_1383, RNA815_7735} |
8. | MligTC455_39843 | 434 | 9.04 | Mlig455_031862 | Neo: - Age: logFC(26M/2M)=0.323 Region-enriched R5: 3.071/0.00013 |
0.955 | - | - | - | 0.955 | - | - | Mlig455_031862 {REF} {Length: 3865} {Smed: dd_Smed_v6_11504_0_1, dd_Smed_v6_11504_0_1, [Score=160, Expect=1e-44]} {RNA1509_38226} {RNA1310_9352.1, RNA1509_38226} {RNA1509_38226, RNA815_18353} | |
9. | MligTC455_49944 | 108 | 2.25 | Mlig455_067437 | Neo: - Age: logFC(26M/2M)=-0.477 Region-enriched R4: 2.865/0.02691 |
GSTP1 | 0.954 | - | - | - | - | 0.954 | - | Mlig455_067437 {REF} {Length: 1036} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=66.1]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=21.1]} {Human: ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=66.2, Expect=9e-13]} {Mouse: ENSMUSG00000097663, Gstp3, glutathione S-transferase pi 3, [Score=56.2, Expect=3e-09]; ENSMUSG00000058216, Gstp3, glutathione S-transferase pi 3, [Score=56.2, Expect=3e-09]; ENSMUSG00000068762, Gstm6, glutathione S-transferase, mu 6, [Score=55.8, Expect=4e-09]} {Celegans: WBGene00001762, gst-14, Glutathione S-Transferase, [Score=64.7, Expect=1e-12]} {RNA1509_34951} {RNA1310_12535} {RNA815_15521.1} |