M. lignano Tomo-Seq
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Results for MligTC455_51802

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51802 2189 45.59 Mlig455_011067

Neo: -

Age: logFC(26M/2M)=0.199

 KPNA4 Mlig455_011067 {REF} {Length: 3382} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=281.5]; Atypical Arm repeat [PF16186.7, score=80.0]; Importin beta binding domain [PF01749.22, score=75.4]; HEAT-like repeat [PF13513.8, score=71.9]; HEAT repeats [PF13646.8, score=65.4]; HEAT repeat [PF02985.24, score=56.5]; Adaptin N terminal region [PF01602.22, score=27.0]; V-ATPase subunit H [PF11698.10, score=26.9]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=25.5]; Armadillo-like [PF04826.15, score=25.2]; Parkin co-regulated protein [PF10274.11, score=19.9]; V-ATPase subunit H [PF03224.16, score=18.1]} {Human: ENSG00000186432, KPNA4, karyopherin subunit alpha 4, [RH, Score=701, Expect=0.0]; ENSG00000102753, KPNA3, karyopherin subunit alpha 3, [RH, Score=696, Expect=0.0]} {Mouse: ENSMUSG00000027782, Kpna4, karyopherin (importin) alpha 4, [RH, Score=701, Expect=0.0]; ENSMUSG00000021929, Kpna3, karyopherin (importin) alpha 3, [RH, Score=696, Expect=0.0]} {Dmel: FBgn0027338, Kap-alpha3, karyopherin alpha3, [RH, Score=646, Expect=0.0]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [RH, Score=613, Expect=0.0]} {Smed: dd_Smed_v6_590_0_1, dd_Smed_v6_590_0_1, [RH, Score=704, Expect=0.0]} {RNA1509_13740, RNA1509_1383} {RNA1310_3813.1, RNA1509_13740, RNA1509_1383} {RNA1509_13740, RNA1509_1383, RNA815_7735}

Cumulative graph for MligTC455_51802

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.655 5.696 0.25379 0.90129
RegionR2 -0.08 5.696 0.75856 1.00000
RegionR3 -0.052 5.696 0.80502 1.00000
RegionR4 0.508 5.696 0.04430 0.17765
RegionR5 0.807 5.696 0.00001 0.00023
RegionR6 -0.164 5.696 0.45133 1.00000
RegionR7 -0.719 5.696 0.01865 0.25166
RegionR8 -0.954 5.696 0.01379 0.22687

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.512 5.696 0.10107 0.81835
RegenerationR2 -0.157 5.696 0.47656 0.86138
RegenerationR3 0.254 5.696 0.29624 0.72754
RegenerationR4 0 5.696 0.99992 1.00000
RegenerationR5 -0.286 5.696 0.19082 0.62178
RegenerationR6 0.643 5.696 0.00858 0.11396
RegenerationBL 0.482 5.696 0.12872 0.42694
RegenerationTP 0.453 5.696 0.19621 0.63576


Genes with expression patterns similar to MligTC455_51802

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51802 2189 45.59 Mlig455_011067

Neo: -

Age: logFC(26M/2M)=0.199

 KPNA4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_011067 {REF} {Length: 3382} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=281.5]; Atypical Arm repeat [PF16186.7, score=80.0]; Importin beta binding domain [PF01749.22, score=75.4]; HEAT-like repeat [PF13513.8, score=71.9]; HEAT repeats [PF13646.8, score=65.4]; HEAT repeat [PF02985.24, score=56.5]; Adaptin N terminal region [PF01602.22, score=27.0]; V-ATPase subunit H [PF11698.10, score=26.9]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=25.5]; Armadillo-like [PF04826.15, score=25.2]; Parkin co-regulated protein [PF10274.11, score=19.9]; V-ATPase subunit H [PF03224.16, score=18.1]} {Human: ENSG00000186432, KPNA4, karyopherin subunit alpha 4, [RH, Score=701, Expect=0.0]; ENSG00000102753, KPNA3, karyopherin subunit alpha 3, [RH, Score=696, Expect=0.0]} {Mouse: ENSMUSG00000027782, Kpna4, karyopherin (importin) alpha 4, [RH, Score=701, Expect=0.0]; ENSMUSG00000021929, Kpna3, karyopherin (importin) alpha 3, [RH, Score=696, Expect=0.0]} {Dmel: FBgn0027338, Kap-alpha3, karyopherin alpha3, [RH, Score=646, Expect=0.0]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [RH, Score=613, Expect=0.0]} {Smed: dd_Smed_v6_590_0_1, dd_Smed_v6_590_0_1, [RH, Score=704, Expect=0.0]} {RNA1509_13740, RNA1509_1383} {RNA1310_3813.1, RNA1509_13740, RNA1509_1383} {RNA1509_13740, RNA1509_1383, RNA815_7735}
2. MligTC455_52362 278 5.79 Mlig455_032543, Mlig455_037930

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.247

 0.967 - - - - 0.967 -

Mlig455_032543 {REF} {Length: 1118} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=59.5]; Ankyrin repeats (many copies) [PF13637.8, score=54.9]; Ankyrin repeat [PF13606.8, score=38.0]; Ankyrin repeats (many copies) [PF13857.8, score=36.3]; Ankyrin repeat [PF00023.32, score=28.6]} {RNA1310_33114} {RNA815_16952}

Mlig455_037930 {REF} {Length: 1123} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=59.5]; Ankyrin repeats (many copies) [PF13637.8, score=54.9]; Ankyrin repeat [PF13606.8, score=38.0]; Ankyrin repeats (many copies) [PF13857.8, score=36.3]; Ankyrin repeat [PF00023.32, score=28.6]} {RNA1310_33114} {RNA815_16952}
3. MligTC455_45593 620 12.91 Mlig455_071089

Neo: -

Age: -

 VCP 0.957 - - - - 0.957 - Mlig455_071089 {REF} {Length: 3261} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=321.1]; AAA+ lid domain [PF17862.3, score=84.4]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=76.4]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=51.5]; AAA ATPase domain [PF13191.8, score=46.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=42.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=41.0]; AAA domain [PF13671.8, score=40.8]; Vps4 C terminal oligomerisation domain [PF09336.12, score=38.5]; AAA domain [PF13401.8, score=37.9]; TIP49 P-loop domain [PF06068.15, score=34.6]; AAA domain [PF13238.8, score=32.0]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=30.4]; RNA helicase [PF00910.24, score=29.8]; AAA domain [PF13173.8, score=29.8]; Magnesium chelatase, subunit ChlI [PF01078.23, score=28.7]; IstB-like ATP binding protein [PF01695.19, score=27.6]; ABC transporter [PF00005.29, score=27.3]; AAA domain [PF13521.8, score=27.1]; P-loop containing dynein motor region [PF12775.9, score=25.9]; AAA domain [PF13207.8, score=24.7]; Parvovirus non-structural protein NS1 [PF01057.19, score=24.5]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.0]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=22.8]; Bacterial dnaA protein [PF00308.20, score=22.7]; ATPase domain predominantly from Archaea [PF01637.20, score=22.4]; AAA domain [PF13481.8, score=22.4]; KaiC [PF06745.15, score=22.1]; Sigma-54 interaction domain [PF00158.28, score=21.5]; Zeta toxin [PF06414.14, score=20.9]; AAA domain [PF13479.8, score=20.3]; Type III restriction enzyme, res subunit [PF04851.17, score=20.1]; NACHT domain [PF05729.14, score=19.6]; Sigma-54 interaction domain [PF14532.8, score=19.1]; NB-ARC domain [PF00931.24, score=19.0]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=18.5]; PhoH-like protein [PF02562.18, score=18.4]; Protein of unknown function (DUF815) [PF05673.15, score=18.4]} {Human: ENSG00000165280, VCP, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Mouse: ENSMUSG00000028452, Vcp, valosin containing protein, [RH, Score=1258, Expect=0.0]} {Dmel: FBgn0261014, TER94, [RH, Score=1257, Expect=0.0]} {Celegans: WBGene00008053, cdc-48.2, Transitional endoplasmic reticulum ATPase homolog 2, [RH, Score=1214, Expect=0.0]} {Smed: dd_Smed_v6_482_0_1, dd_Smed_v6_482_0_1, [RH, Score=1300, Expect=0.0]} {RNA1509_10842} {RNA1310_14598.1} {RNA815_1672.1}

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