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Results for MligTC455_46558

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_46558 1383 28.82 Mlig455_031428

Neo: -

Age: -

Regeneration-downregulated TP: -1.779

Regeneration-depleted TP: -1.779

TANC1 Mlig455_031428 {REF} {Length: 2092} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=49.3]; Ankyrin repeats (many copies) [PF13857.8, score=47.2]; Ankyrin repeat [PF13606.8, score=41.6]; Ankyrin repeats (many copies) [PF13637.8, score=36.2]; Ankyrin repeat [PF00023.32, score=36.1]} {Human: ENSG00000115183, TANC1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=55.5, Expect=1e-07]; ENSG00000145362, ANK2, ankyrin 2, [Score=53.5, Expect=7e-07]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=52.0, Expect=1e-06]; ENSMUSG00000005251, Ripk4, receptor-interacting serine-threonine kinase 4, [Score=51.6, Expect=1e-06]; ENSMUSG00000035168, Tanc1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=50.4, Expect=3e-06]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=55.8, Expect=6e-08]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=50.4, Expect=2e-06]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [Score=52.0, Expect=3e-07]} {RNA1509_19702, RNA1509_30097} {RNA1310_14830, RNA1509_19702, RNA1509_30097} {RNA1509_19702, RNA1509_30097, RNA815_5101}

Cumulative graph for MligTC455_46558

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.811 5.046 0.34527 0.98902
RegionR2 -0.012 5.046 0.97281 1.00000
RegionR3 -0.248 5.046 0.41612 0.94118
RegionR4 0.188 5.046 0.58290 0.89905
RegionR5 -0.621 5.046 0.03817 0.15410
RegionR6 -0.077 5.046 0.79933 1.00000
RegionR7 0.615 5.046 0.07141 0.51430
RegionR8 0.967 5.046 0.01643 0.24978

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.927 5.046 0.22363 0.95604
RegenerationR2 0.01 5.046 0.97560 1.00000
RegenerationR3 -0.27 5.046 0.44031 0.82746
RegenerationR4 -0.56 5.046 0.10668 0.50394
RegenerationR5 -0.303 5.046 0.38492 0.78903
RegenerationR6 -0.329 5.046 0.35267 0.69802
RegenerationBL -1.179 5.046 0.00269 0.04378
RegenerationTP -1.779 5.046 0.00004 0.00641 Specific for TP: -1.779


Genes with expression patterns similar to MligTC455_46558

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_46558 1383 28.82 Mlig455_031428

Neo: -

Age: -

Regeneration-downregulated TP: -1.779

Regeneration-depleted TP: -1.779

TANC1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_031428 {REF} {Length: 2092} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=49.3]; Ankyrin repeats (many copies) [PF13857.8, score=47.2]; Ankyrin repeat [PF13606.8, score=41.6]; Ankyrin repeats (many copies) [PF13637.8, score=36.2]; Ankyrin repeat [PF00023.32, score=36.1]} {Human: ENSG00000115183, TANC1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=55.5, Expect=1e-07]; ENSG00000145362, ANK2, ankyrin 2, [Score=53.5, Expect=7e-07]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=52.0, Expect=1e-06]; ENSMUSG00000005251, Ripk4, receptor-interacting serine-threonine kinase 4, [Score=51.6, Expect=1e-06]; ENSMUSG00000035168, Tanc1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=50.4, Expect=3e-06]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=55.8, Expect=6e-08]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=50.4, Expect=2e-06]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [Score=52.0, Expect=3e-07]} {RNA1509_19702, RNA1509_30097} {RNA1310_14830, RNA1509_19702, RNA1509_30097} {RNA1509_19702, RNA1509_30097, RNA815_5101}
2. MligTC455_38922 1324 27.57 Mlig455_055899

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.333

MX2 2.686 - - 0.841 - 0.954 0.891 Mlig455_055899 {REF} {Length: 3320} {Pfam: Dynamin central region [PF01031.22, score=177.8]; Dynamin family [PF00350.25, score=125.7]; Dynamin GTPase effector domain [PF02212.20, score=46.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.2]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=308, Expect=3e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=182, Expect=9e-48]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=176, Expect=6e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=198, Expect=2e-53]} {RNA1509_37170, RNA1509_6400} {RNA1310_6542.1, RNA1509_37170, RNA1509_6400} {RNA1509_37170, RNA1509_6400, RNA815_1426.1}
3. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

MX2 2.667 0.768 - - - 0.950 0.949 Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
4. MligTC455_41702 2176 45.34 Mlig455_055307

Neo: -

Age: Down-Up-Up

CYP2C8 2.623 - - - 0.767 0.953 0.903 Mlig455_055307 {REF} {Length: 2612} {Pfam: Cytochrome P450 [PF00067.24, score=306.8]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=259, Expect=6e-80]} {Mouse: ENSMUSG00000030483, Cyp2b10, cytochrome P450, family 2, subfamily b, polypeptide 10, [Score=257, Expect=2e-79]; ENSMUSG00000040660, Cyp2b9, cytochrome P450, family 2, subfamily b, polypeptide 9, [Score=249, Expect=2e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=247, Expect=2e-75]; ENSMUSG00000040650, Cyp2b23, cytochrome P450, family 2, subfamily b, polypeptide 23, [Score=246, Expect=3e-75]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=246, Expect=1e-74]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=246, Expect=1e-74]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=180, Expect=4e-50]} {Celegans: WBGene00018261, cyp-33C5, CYtochrome P450 family, [Score=221, Expect=7e-66]} {Smed: dd_Smed_v6_2351_0_1, dd_Smed_v6_2351_0_1, [RH, Score=279, Expect=4e-88]} {RNA1509_10256, RNA1509_15694, RNA1509_40717} {RNA1310_11391, RNA1509_10256, RNA1509_15694, RNA1509_40717} {RNA1509_10256, RNA1509_15694, RNA1509_40717, RNA815_585.2}
5. MligTC455_39612 861 17.93 Mlig455_019206

Neo: -

Age: logFC(26M/2M)=-0.343

DLEC1 2.618 - - 0.853 0.805 0.960 - Mlig455_019206 {REF} {Length: 7152} {TRANSSPLICED} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=68.8]; Flagellar-associated PapD-like [PF14874.8, score=25.0]} {Human: ENSG00000008226, DLEC1, DLEC1, cilia and flagella associated protein, [RH, Score=721, Expect=0.0]} {Mouse: ENSMUSG00000038060, Dlec1, deleted in lung and esophageal cancer 1, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_10833_0_1, dd_Smed_v6_10833_0_1, [RH, Score=813, Expect=0.0]} {RNA1509_3454} {RNA1310_859.1, RNA1509_3454} {RNA1509_3454, RNA815_262}
6. MligTC455_53471 1325 27.61 Mlig455_015629

Neo: -

Age: logFC(26M/2M)=-0.386

CFAP65 2.589 - - 0.793 0.819 0.977 - Mlig455_015629 {REF} {Length: 5817} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=93.0]; MSP (Major sperm protein) domain [PF00635.28, score=47.3]; Protein of unknown function (DUF1573) [PF07610.13, score=22.4]; Transmembrane protein 131-like N-terminal [PF12371.10, score=21.0]} {Human: ENSG00000181378, CFAP65, cilia and flagella associated protein 65, [RH, Score=850, Expect=0.0]} {Mouse: ENSMUSG00000047021, Cfap65, cilia and flagella associated protein 65, [RH, Score=844, Expect=0.0]} {Smed: dd_Smed_v6_12428_0_1, dd_Smed_v6_12428_0_1, [RH, Score=1276, Expect=0.0]} {RNA1509_19700} {RNA1310_760, RNA1509_19700} {RNA1509_19700, RNA815_222.1}
7. MligTC455_50366 4401 91.69 Mlig455_031856, Mlig455_031942

Neo: -

Age: logFC(26M/2M)=-0.385

Region-enriched R2: 1.195/0.00796

CFAP100 2.55 0.717 - - 0.880 0.953 -

Mlig455_031856 {REF} {Length: 2306} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4200) [PF13863.8, score=102.4]} {Human: ENSG00000163885, CFAP100, cilia and flagella associated protein 100, [RH, Score=363, Expect=3e-117]} {Mouse: ENSMUSG00000048794, Cfap100, cilia and flagella associated protein 100, [RH, Score=357, Expect=6e-115]} {Smed: dd_Smed_v6_6518_0_1, dd_Smed_v6_6518_0_1, [RH, Score=466, Expect=2e-158]} {RNA1509_2849, RNA1509_9395} {RNA1310_12917.1, RNA1509_2849} {RNA1509_2849, RNA815_2819}

Mlig455_031942 {REF} {Length: 2061} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4200) [PF13863.8, score=102.4]} {Human: ENSG00000163885, CFAP100, cilia and flagella associated protein 100, [RH, Score=363, Expect=3e-117]} {Mouse: ENSMUSG00000048794, Cfap100, cilia and flagella associated protein 100, [RH, Score=357, Expect=6e-115]} {Smed: dd_Smed_v6_6518_0_1, dd_Smed_v6_6518_0_1, [RH, Score=466, Expect=2e-158]} {RNA1509_2849} {RNA1310_12917.1} {RNA815_2819}
8. MligTC455_24074 1066 22.21 Mlig455_048222

Neo: -

Age: -

Region-enriched R2: 1.734/0.02628

2.493 - - 0.786 0.748 0.959 - Mlig455_048222 {REF} {Length: 2364} {Smed: dd_Smed_v6_8763_0_1, dd_Smed_v6_8763_0_1, [RH, Score=101, Expect=1e-23]} {RNA1509_5814} {RNA1310_13945, RNA1509_5814} {RNA1509_5814, RNA815_5072}
9. MligTC455_46850 265 5.52 Mlig455_005746

Neo: -

Age: -

Region-enriched R4: 2.659/0.01708

2.478 0.716 - - 0.807 0.955 - Mlig455_005746 {REF} {Length: 3392} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=84.7, Expect=3e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=68.9, Expect=1e-11]} {RNA1509_46369, RNA1509_7522} {RNA1310_3662, RNA1509_46369, RNA1509_7522} {RNA1509_46369, RNA1509_7522, RNA815_5689}
10. MligTC455_40258 785 16.35 Mlig455_029061

Neo: -

Age: logFC(26M/2M)=-0.289

Region-enriched R2: 1.297/0.02040

Regeneration-downregulated R5: -1.663

Regeneration-depleted R5: -1.663

SLC10A3 2.464 - - 0.751 - 0.757 0.956 Mlig455_029061 {REF} {Length: 2350} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=98.6]} {Human: ENSG00000126903, SLC10A3, solute carrier family 10 member 3, [RH, Score=143, Expect=9e-37]; ENSG00000253598, SLC10A5, solute carrier family 10 member 5, [RH, Score=138, Expect=3e-35]} {Mouse: ENSMUSG00000058921, Slc10a5, solute carrier family 10 (sodium/bile acid cotransporter family), member 5, [RH, Score=140, Expect=5e-36]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [RH, Score=139, Expect=1e-35]} {Dmel: FBgn0030638, CG11655, [RH, Score=184, Expect=6e-52]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=204, Expect=5e-59]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [Score=234, Expect=2e-71]} {RNA1509_26597, RNA1509_7189} {RNA1310_14247, RNA1509_26597, RNA1509_7189} {RNA1509_26597, RNA1509_7189, RNA815_5207}
11. MligTC455_44144 1917 39.94 Mlig455_013403

Neo: -

Age: logFC(26M/2M)=-0.387

TNKS 2.448 - - - 0.769 0.715 0.964 Mlig455_013403 {REF} {Length: 3109} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=73.2]; Ankyrin repeats (many copies) [PF13857.8, score=57.0]; Ankyrin repeats (many copies) [PF13637.8, score=54.5]; Ion transport protein [PF00520.33, score=51.4]; Ankyrin repeat [PF00023.32, score=50.9]; Ankyrin repeat [PF13606.8, score=46.3]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=88.6, Expect=3e-17]; ENSG00000285372, AC270292.3, tankyrase, [Score=87.4, Expect=7e-17]; ENSG00000107854, TNKS2, tankyrase 2, [Score=84.3, Expect=6e-16]} {Mouse: ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=87.4, Expect=4e-17]; ENSMUSG00000024811, Tnks2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, [Score=84.0, Expect=5e-16]} {Dmel: FBgn0004647, N, Notch, [Score=80.1, Expect=7e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=82.8, Expect=6e-16]} {Smed: dd_Smed_v6_8547_0_1, dd_Smed_v6_8547_0_1, [Score=79.3, Expect=6e-15]} {RNA1509_2994} {RNA1310_1688.1, RNA1509_2994} {RNA1509_2994, RNA815_1415.1}
12. MligTC455_51757 1487 30.98 Mlig455_034252, Mlig455_067287

Neo: -

Age: -

TTC25 1.858 - - - 0.903 0.955 -

Mlig455_034252 {REF} {Length: 2484} {Pfam: Tetratricopeptide repeat [PF07719.19, score=74.5]; Tetratricopeptide repeat [PF00515.30, score=56.9]; Tetratricopeptide repeat [PF13424.8, score=54.5]; Tetratricopeptide repeat [PF13181.8, score=42.2]; Tetratricopeptide repeat [PF13428.8, score=37.0]; Tetratricopeptide repeat [PF13432.8, score=36.8]; Tetratricopeptide repeat [PF14559.8, score=33.7]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=27.2]; Tetratricopeptide repeat [PF13176.8, score=26.6]; TPR repeat [PF13414.8, score=25.9]; Tetratricopeptide repeat [PF13371.8, score=25.0]; Domain of Unknown Function (DUF3856) [PF12968.9, score=23.9]; Tetratricopeptide repeat [PF13431.8, score=20.8]} {Human: ENSG00000204815, TTC25, tetratricopeptide repeat domain 25, [RH, Score=401, Expect=3e-132]} {Mouse: ENSMUSG00000006784, Ttc25, tetratricopeptide repeat domain 25, [RH, Score=420, Expect=4e-140]} {Dmel: FBgn0034692, CG13502, [RH, Score=152, Expect=7e-42]} {Smed: dd_Smed_v6_3933_0_1, dd_Smed_v6_3933_0_1, [RH, Score=527, Expect=0.0]} {RNA1509_2214, RNA1509_26740} {RNA1310_11497, RNA1509_26740} {RNA1509_26740, RNA815_2107.1}

Mlig455_067287 {REF} {Length: 2412} {Pfam: Tetratricopeptide repeat [PF07719.19, score=74.5]; Tetratricopeptide repeat [PF00515.30, score=56.9]; Tetratricopeptide repeat [PF13424.8, score=54.5]; Tetratricopeptide repeat [PF13181.8, score=42.2]; Tetratricopeptide repeat [PF13428.8, score=37.0]; Tetratricopeptide repeat [PF13432.8, score=36.8]; Tetratricopeptide repeat [PF14559.8, score=33.7]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=27.2]; Tetratricopeptide repeat [PF13176.8, score=26.6]; TPR repeat [PF13414.8, score=25.9]; Tetratricopeptide repeat [PF13371.8, score=25.0]; Domain of Unknown Function (DUF3856) [PF12968.9, score=23.9]; Tetratricopeptide repeat [PF13431.8, score=20.8]} {Human: ENSG00000204815, TTC25, tetratricopeptide repeat domain 25, [RH, Score=401, Expect=3e-132]} {Mouse: ENSMUSG00000006784, Ttc25, tetratricopeptide repeat domain 25, [RH, Score=420, Expect=4e-140]} {Dmel: FBgn0034692, CG13502, [RH, Score=152, Expect=7e-42]} {Smed: dd_Smed_v6_3933_0_1, dd_Smed_v6_3933_0_1, [RH, Score=527, Expect=0.0]} {RNA1509_2214} {RNA1310_11497} {RNA815_2107.1}
13. MligTC455_23589 1204 25.08 Mlig455_013096, Mlig455_013189

Neo: -

Age: -

CNBD1 1.84 - - - - 0.950 0.890

Mlig455_013096 {REF} {Length: 1719} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.0]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=213, Expect=2e-63]} {RNA1509_35878} {RNA1310_17903} {RNA815_7217}

Mlig455_013189 {REF} {Length: 1713} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.1]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=212, Expect=5e-63]} {RNA1509_35878} {RNA1310_17903, RNA1509_35878} {RNA1509_35878, RNA815_7217}
14. MligTC455_46851 507 10.56 Mlig455_059440

Neo: -

Age: logFC(26M/2M)=-0.309

1.834 - - - - 0.952 0.882 Mlig455_059440 {REF} {Length: 3521} {TRANSSPLICED} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=85.5, Expect=2e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=72.8, Expect=7e-13]} {RNA1509_28804, RNA1509_7522} {RNA1310_3662, RNA1509_28804} {RNA1509_28804, RNA815_5689}
15. MligTC455_23642 573 11.93 Mlig455_069008

Neo: -

Age: logFC(26M/2M)=0.738

ACTB 1.824 - - - 0.861 0.963 - Mlig455_069008 {REF} {Length: 2243} {Pfam: Actin [PF00022.21, score=267.5]; Protein kinase domain [PF00069.27, score=203.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=20.5]} {Human: ENSG00000075624, ACTB, actin beta, [Score=417, Expect=3e-141]; ENSG00000184009, ACTG1, actin gamma 1, [Score=417, Expect=5e-141]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=4e-136]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=5e-136]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [Score=403, Expect=2e-135]; ENSG00000169067, ACTBL2, actin, beta like 2, [Score=401, Expect=9e-135]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [Score=400, Expect=1e-134]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [Score=417, Expect=4e-141]; ENSMUSG00000029580, Actb, actin, beta, [Score=417, Expect=2e-141]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=2e-136]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=4e-136]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [Score=404, Expect=5e-136]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [Score=403, Expect=1e-135]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [Score=400, Expect=8e-135]} {Dmel: FBgn0000042, Act5C, Actin 5C, [Score=417, Expect=3e-141]} {Celegans: WBGene00000064, act-2, Actin-2, [Score=418, Expect=6e-142]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [Score=419, Expect=4e-142]} {RNA1509_28185} {RNA1310_11665} {RNA815_6928}
16. MligTC455_16046 633 13.18 Mlig455_022748

Neo: -

Age: Down-Up-Down

CDYL 1.823 - - 0.854 - 0.969 - Mlig455_022748 {REF} {Length: 8355} {TRANSSPLICED} {Pfam: Chromo (CHRromatin Organisation MOdifier) domain [PF00385.26, score=46.1]; Ankyrin repeats (3 copies) [PF12796.9, score=27.1]; Ankyrin repeat [PF13606.8, score=21.5]} {Human: ENSG00000153046, CDYL, chromodomain Y like, [Score=56.2, Expect=7e-08]; ENSG00000196199, MPHOSPH8, M-phase phosphoprotein 8, [Score=53.9, Expect=5e-07]} {Mouse: ENSMUSG00000031758, Cdyl2, chromodomain protein, Y chromosome-like 2, [Score=53.5, Expect=3e-07]; ENSMUSG00000059288, Cdyl, chromodomain protein, Y chromosome-like, [Score=52.4, Expect=7e-07]; ENSMUSG00000079184, Mphosph8, M-phase phosphoprotein 8, [Score=52.4, Expect=9e-07]} {Dmel: FBgn0004400, rhi, rhino, [Score=52.0, Expect=6e-07]} {Smed: dd_Smed_v6_8960_0_1, dd_Smed_v6_8960_0_1, [Score=60.5, Expect=1e-09]} {RNA1509_12680, RNA1509_39952} {RNA1310_20959.1, RNA1509_39952} {RNA1509_39952, RNA815_8097}
17. MligTC455_26281 697 14.53 Mlig455_022872

Neo: -

Age: -

CYP2U1 1.81 - - - 0.962 0.848 - Mlig455_022872 {REF} {Length: 2676} {Pfam: Cytochrome P450 [PF00067.24, score=219.8]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=167, Expect=2e-49]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=163, Expect=1e-46]; ENSG00000186104, CYP2R1, cytochrome P450 family 2 subfamily R member 1, [Score=160, Expect=2e-47]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=159, Expect=3e-45]} {Mouse: ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [Score=164, Expect=5e-47]; ENSMUSG00000030483, Cyp2b10, cytochrome P450, family 2, subfamily b, polypeptide 10, [Score=163, Expect=1e-46]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=163, Expect=1e-46]; ENSMUSG00000040660, Cyp2b9, cytochrome P450, family 2, subfamily b, polypeptide 9, [Score=162, Expect=2e-46]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=162, Expect=3e-46]; ENSMUSG00000049685, Cyp2g1, cytochrome P450, family 2, subfamily g, polypeptide 1, [Score=162, Expect=3e-46]; ENSMUSG00000040583, Cyp2b13, cytochrome P450, family 2, subfamily b, polypeptide 13, [Score=162, Expect=2e-46]; ENSMUSG00000030670, Cyp2r1, cytochrome P450, family 2, subfamily r, polypeptide 1, [Score=157, Expect=3e-46]; ENSMUSG00000040650, Cyp2b23, cytochrome P450, family 2, subfamily b, polypeptide 23, [Score=156, Expect=3e-44]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=134, Expect=5e-36]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=160, Expect=1e-45]} {Smed: dd_Smed_v6_2351_0_3, dd_Smed_v6_2351_0_3, [Score=201, Expect=2e-61]} {RNA1509_32151} {RNA1310_10092} {RNA815_723}
18. MligTC455_51791 4667 97.23 Mlig455_038198, Mlig455_038377

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.223

PRKAR2A 1.805 - - - 0.954 0.851 -

Mlig455_038198 {REF} {Length: 1734} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=146.5]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=42.3]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [RH, Score=383, Expect=2e-131]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [RH, Score=387, Expect=6e-133]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [RH, Score=410, Expect=1e-142]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=215, Expect=1e-66]} {Smed: dd_Smed_v6_2902_0_1, dd_Smed_v6_2902_0_1, [RH, Score=472, Expect=3e-167]} {RNA1509_18015, RNA1509_20723, RNA1509_3645} {RNA1310_16806, RNA1509_18015, RNA1509_20723} {RNA1509_18015, RNA1509_20723, RNA815_6455.1}

Mlig455_038377 {REF} {Length: 2125} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=147.2]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=42.3]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [RH, Score=385, Expect=6e-132]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [RH, Score=389, Expect=1e-133]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [RH, Score=410, Expect=2e-142]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=215, Expect=1e-66]} {Smed: dd_Smed_v6_2902_0_1, dd_Smed_v6_2902_0_1, [RH, Score=471, Expect=1e-166]} {RNA1509_18612, RNA1509_20187, RNA1509_3645, RNA1509_44370} {RNA1310_16806, RNA1509_18612, RNA1509_20187, RNA1509_3645, RNA1509_44370} {RNA1509_18612, RNA1509_20187, RNA1509_3645, RNA1509_44370, RNA815_6455.1}
19. MligTC455_46667 769 16.02 Mlig455_007827

Neo: -

Age: -

Region-enriched R2: 2.396/0.00004

PLSCR3 1.789 - - - - 0.837 0.952 Mlig455_007827 {REF} {Length: 946} {Pfam: Scramblase [PF03803.17, score=174.8]} {Human: ENSG00000187838, PLSCR3, phospholipid scramblase 3, [Score=155, Expect=1e-46]; ENSG00000284009, PLSCR3, phospholipid scramblase 3, [Score=155, Expect=1e-46]; ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=153, Expect=2e-46]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=162, Expect=4e-49]; ENSMUSG00000019461, Plscr3, phospholipid scramblase 3, [Score=158, Expect=9e-48]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=151, Expect=7e-46]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=124, Expect=4e-35]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [Score=206, Expect=3e-66]} {RNA1509_32731, RNA1509_35060, RNA1509_60038} {RNA1310_24943, RNA1509_32731, RNA1509_35060, RNA1509_60038} {RNA1509_32731, RNA1509_35060, RNA1509_60038, RNA815_10647}
20. MligTC455_42966 424 8.83 Mlig455_065372

Neo: -

Age: logFC(26M/2M)=-0.345

SPATA6L 1.768 - - - 0.952 - 0.816 Mlig455_065372 {REF} {Length: 3682} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=127.3]} {Human: ENSG00000106686, SPATA6L, spermatogenesis associated 6 like, [RH, Score=95.9, Expect=8e-22]} {Mouse: ENSMUSG00000064202, 4430402I18Rik, RIKEN cDNA 4430402I18 gene, [RH, Score=100, Expect=6e-23]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [RH, Score=186, Expect=1e-55]} {RNA1509_23645} {RNA1310_24559, RNA1509_23645} {RNA1509_23645, RNA815_31401}
21. MligTC455_44145 1616 33.67 Mlig455_013447

Neo: -

Age: -

1.759 - - - 0.807 - 0.952 Mlig455_013447 {REF} {Length: 841} {RNA1509_20243} {RNA1310_1688.1} {RNA815_1415.1}
22. MligTC455_03037 319 6.64 Mlig455_058181, Mlig455_058205

Neo: -

Age: Down-Up-Up

FAM126A 1.751 - - - 0.793 0.958 -

Mlig455_058181 {REF} {Length: 1804} {TRANSSPLICED} {Pfam: Hyccin [PF09790.11, score=125.7]} {Human: ENSG00000122591, FAM126A, family with sequence similarity 126 member A, [RH, Score=80.5, Expect=7e-16]} {Mouse: ENSMUSG00000038174, Fam126b, family with sequence similarity 126, member B, [Score=86.3, Expect=1e-17]} {Dmel: FBgn0034269, CG6406, [RH, Score=97.4, Expect=1e-21]} {Celegans: WBGene00017037, D1069.3, [Score=51.6, Expect=7e-07]} {RNA1509_44354} {RNA1310_17018} {RNA815_37064}

Mlig455_058205 {REF} {Length: 1804} {TRANSSPLICED} {Pfam: Hyccin [PF09790.11, score=125.7]} {Human: ENSG00000122591, FAM126A, family with sequence similarity 126 member A, [RH, Score=80.5, Expect=7e-16]} {Mouse: ENSMUSG00000038174, Fam126b, family with sequence similarity 126, member B, [Score=86.3, Expect=1e-17]} {Dmel: FBgn0034269, CG6406, [RH, Score=97.4, Expect=1e-21]} {Celegans: WBGene00017037, D1069.3, [Score=51.6, Expect=7e-07]} {RNA1509_44354} {RNA1310_17018, RNA1509_44354} {RNA1509_44354, RNA815_37064}
23. MligTC455_23564 1404 29.25 Mlig455_012182

Neo: -

Age: logFC(26M/2M)=-0.411

1.746 - - - 0.785 0.961 - Mlig455_012182 {REF} {Length: 3676} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=164, Expect=4e-41]} {RNA1509_54958} {RNA1310_4804} {RNA815_699}
24. MligTC455_20230 1282 26.71 Mlig455_003493, Mlig455_015562

Neo: -

Age: logFC(26M/2M)=-0.236

FAM227A, FAM227B 1.744 - - - 0.763 0.981 -

Mlig455_003493 {REF} {Length: 2231} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.0]} {Human: ENSG00000184949, FAM227A, family with sequence similarity 227 member A, [Score=111, Expect=2e-25]} {Mouse: ENSMUSG00000042564, Fam227a, family with sequence similarity 227, member A, [RH, Score=96.7, Expect=8e-21]; ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=93.6, Expect=6e-20]} {Smed: dd_Smed_v6_15102_0_3, dd_Smed_v6_15102_0_3, [Score=157, Expect=3e-42]} {RNA1509_44428} {RNA1310_6983.2} {RNA815_5876}

Mlig455_015562 {REF} {Length: 2171} {TRANSSPLICED} {Pfam: Protein of unknown function [PF14922.8, score=146.7]} {Human: ENSG00000166262, FAM227B, family with sequence similarity 227 member B, [RH, Score=107, Expect=2e-24]} {Mouse: ENSMUSG00000027209, Fam227b, family with sequence similarity 227, member B, [RH, Score=98.6, Expect=1e-21]} {Smed: dd_Smed_v6_15102_0_7, dd_Smed_v6_15102_0_7, [Score=178, Expect=5e-50]} {RNA1509_58462} {RNA1310_11701} {RNA815_12354}
25. MligTC455_53450 4370 91.04 Mlig455_044396

Neo: -

Age: logFC(26M/2M)=-0.245

AK7 1.743 - - - 0.790 0.953 - Mlig455_044396 {REF} {Length: 2634} {Pfam: Dpy-30 motif [PF05186.15, score=58.4]; Adenylate kinase [PF00406.24, score=48.5]; AAA domain [PF13207.8, score=29.4]} {Human: ENSG00000140057, AK7, adenylate kinase 7, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000041323, Ak7, adenylate kinase 7, [RH, Score=679, Expect=0.0]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00002879, let-754, Adenylate kinase, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_5880_0_1, dd_Smed_v6_5880_0_1, [RH, Score=627, Expect=0.0]} {RNA1509_19178, RNA1509_580} {RNA1310_7753.1, RNA1509_19178, RNA1509_580} {RNA1509_19178, RNA1509_580, RNA815_2574}
26. MligTC455_31001 1473 30.69 Mlig455_024877, Mlig455_068443

Neo: -

Age: -

Region-enriched R8: 2.076/0.01787

MPEG1 1.736 - - 0.769 - 0.967 -

Mlig455_024877 {REF} {Length: 3371} {Pfam: MAC/Perforin domain [PF01823.21, score=139.0]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [RH, Score=362, Expect=4e-108]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [RH, Score=368, Expect=2e-110]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [RH, Score=355, Expect=1e-106]} {RNA1509_21688, RNA1509_30083, RNA1509_44998, RNA1509_4699} {RNA1310_4591, RNA1509_21688, RNA1509_30083, RNA1509_44998} {RNA1509_21688, RNA1509_30083, RNA1509_44998, RNA815_1433.1}

Mlig455_068443 {REF} {Length: 5971} {Pfam: MAC/Perforin domain [PF01823.21, score=139.0]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [RH, Score=362, Expect=4e-108]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [RH, Score=368, Expect=2e-110]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [RH, Score=355, Expect=1e-106]} {RNA1509_4699} {RNA1310_4591} {RNA815_1433.1}
27. MligTC455_51696 624 12.99 Mlig455_011356

Neo: -

Age: -

FAM47E 1.724 - - - 0.773 0.951 - Mlig455_011356 {REF} {Length: 2028} {Pfam: FAM47 family [PF14642.8, score=51.3]} {Human: ENSG00000189157, FAM47E, family with sequence similarity 47 member E, [RH, Score=138, Expect=9e-36]} {Mouse: ENSMUSG00000078315, Fam47c, family with sequence similarity 47, member C, [RH, Score=119, Expect=6e-29]} {Smed: dd_Smed_v6_10346_0_1, dd_Smed_v6_10346_0_1, [RH, Score=293, Expect=6e-95]} {RNA1509_41096, RNA1509_54260, RNA1509_8031} {RNA1310_12665, RNA1509_41096, RNA1509_54260} {RNA1509_41096, RNA1509_54260, RNA815_4489.1}
28. MligTC455_32792 314 6.55 Mlig455_010871

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.924/0.00688

1.706 - - - 0.742 0.964 - Mlig455_010871 {REF} {Length: 1226} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=23.1]} {Smed: dd_Smed_v6_5882_0_1, dd_Smed_v6_5882_0_1, [Score=73.9, Expect=3e-15]} {RNA1509_54110} {RNA1310_37559} {RNA815_18549}
29. MligTC455_23002 1386 28.88 Mlig455_066079, Mlig455_066121

Neo: -

Age: Down-Down-Up

ANKRD50 1.699 - - - 0.714 0.985 -

Mlig455_066079 {REF} {Length: 4539} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=152.7]; Ankyrin repeats (many copies) [PF13637.8, score=140.9]; Ankyrin repeat [PF13606.8, score=112.2]; Ankyrin repeat [PF00023.32, score=105.1]; Ankyrin repeats (many copies) [PF13857.8, score=100.0]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=134, Expect=8e-34]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=131, Expect=4e-33]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=114, Expect=3e-27]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=117, Expect=1e-28]} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA1509_5303} {RNA1310_6276, RNA1509_33878, RNA1509_47884, RNA1509_50045} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA815_1153}

Mlig455_066121 {REF} {Length: 4098} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=236.7]; Ankyrin repeats (many copies) [PF13637.8, score=202.9]; Protein kinase domain [PF00069.27, score=191.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=162.2]; Ankyrin repeat [PF13606.8, score=159.1]; Ankyrin repeat [PF00023.32, score=144.3]; Ankyrin repeats (many copies) [PF13857.8, score=135.5]; ABC1 atypical kinase-like domain [PF03109.18, score=32.5]; Fungal protein kinase [PF17667.3, score=31.9]; Kinase-like [PF14531.8, score=28.5]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=203, Expect=4e-53]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=201, Expect=1e-52]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=158, Expect=3e-39]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=157, Expect=5e-39]} {Smed: dd_Smed_v6_11663_0_4, dd_Smed_v6_11663_0_4, [Score=198, Expect=2e-53]} {RNA1509_5303} {RNA1310_6276} {RNA815_1153}
30. MligTC455_27609 231 4.8 Mlig455_031171

Neo: -

Age: Up-Down-Down

RYR2 1.685 - - - 0.729 0.956 - Mlig455_031171 {REF} {Length: 1840} {Human: ENSG00000198626, RYR2, ryanodine receptor 2, [Score=57.0, Expect=9e-10]; ENSG00000198838, RYR3, ryanodine receptor 3, [Score=55.8, Expect=2e-09]; ENSG00000196218, RYR1, ryanodine receptor 1, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000021313, Ryr2, ryanodine receptor 2, cardiac, [Score=57.0, Expect=6e-10]; ENSMUSG00000057378, Ryr3, ryanodine receptor 3, [Score=56.2, Expect=1e-09]; ENSMUSG00000030592, Ryr1, ryanodine receptor 1, skeletal muscle, [Score=55.1, Expect=3e-09]} {Dmel: FBgn0011286, RyR, Ryanodine receptor, [Score=52.8, Expect=1e-08]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=99.4, Expect=4e-25]} {RNA1509_17046} {RNA1310_1857} {RNA815_62.1}
31. MligTC455_24852 1411 29.39 Mlig455_012420

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.287

FBXO16 1.682 - - - - 0.719 0.963 Mlig455_012420 {REF} {Length: 3757} {Pfam: F-box-like [PF12937.9, score=34.0]; F-box domain [PF00646.35, score=22.7]} {Human: ENSG00000214050, FBXO16, F-box protein 16, [Score=110, Expect=5e-26]} {Mouse: ENSMUSG00000034532, Fbxo16, F-box protein 16, [Score=107, Expect=5e-25]} {Dmel: FBgn0041171, ago, archipelago, [Score=58.2, Expect=2e-08]} {Smed: dd_Smed_v6_12714_0_1, dd_Smed_v6_12714_0_1, [Score=112, Expect=3e-27]} {RNA1509_8187} {RNA1310_37024} {RNA815_17035}
32. MligTC455_50148 595 12.39 Mlig455_006502, Mlig455_006621

Neo: -

Age: -

Region-enriched R4: 1.783/0.00382

ZBBX 1.662 - - - 0.703 0.959 -

Mlig455_006502 {REF} {Length: 3171} {TRANSSPLICED} {Pfam: Cytoplasmic polyadenylation element-binding protein ZZ domain [PF16366.7, score=18.8]} {Human: ENSG00000169064, ZBBX, zinc finger B-box domain containing, [RH, Score=78.6, Expect=3e-14]} {Mouse: ENSMUSG00000034151, Zbbx, zinc finger, B-box domain containing, [RH, Score=89.4, Expect=6e-18]} {Smed: dd_Smed_v6_11048_0_1, dd_Smed_v6_11048_0_1, [RH, Score=139, Expect=3e-34]} {RNA1509_10989, RNA1509_54948} {RNA1310_3743, RNA1509_10989, RNA1509_54948} {RNA1509_10989, RNA1509_54948, RNA815_5872}

Mlig455_006621 {REF} {Length: 3128} {TRANSSPLICED} {Human: ENSG00000169064, ZBBX, zinc finger B-box domain containing, [RH, Score=80.1, Expect=9e-15]} {Mouse: ENSMUSG00000034151, Zbbx, zinc finger, B-box domain containing, [RH, Score=89.0, Expect=9e-18]} {Smed: dd_Smed_v6_11048_0_1, dd_Smed_v6_11048_0_1, [RH, Score=139, Expect=3e-34]} {RNA1509_10989} {RNA1310_3743} {RNA815_5872}
33. MligTC455_39608 6604 137.59 Mlig455_023921, Mlig455_046482

Neo: -

Age: -

APP 1.655 - - - 0.705 0.950 -

Mlig455_023921 {REF} {Length: 3702} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=48.7]; E2 domain of amyloid precursor protein [PF12925.9, score=43.8]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.1]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.3, Expect=3e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.0, Expect=3e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.9, Expect=6e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=101, Expect=4e-22]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=134, Expect=7e-33]} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1310_3149.1, RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900, RNA815_958.1}

Mlig455_046482 {REF} {Length: 3710} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=47.8]; E2 domain of amyloid precursor protein [PF12925.9, score=43.1]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.2]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.7, Expect=2e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.3, Expect=2e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.5, Expect=9e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=103, Expect=9e-23]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=138, Expect=3e-34]} {RNA1509_11651, RNA1509_35488} {RNA1310_3149.1, RNA1509_35488} {RNA1509_35488, RNA815_958.1}
34. MligTC455_18205 1930 40.21 Mlig455_013121

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.975

CALM3 0.978 - - - - - 0.978 Mlig455_013121 {REF} {Length: 709} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=52.2]; EF-hand domain pair [PF13833.8, score=37.1]; EF-hand domain [PF14658.8, score=37.0]; EF-hand domain [PF13405.8, score=25.7]; EF hand [PF00036.34, score=25.5]; Uncharacterised protein family (UPF0154) [PF03672.15, score=22.2]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=137, Expect=6e-42]; ENSG00000143933, CALM2, calmodulin 2, [Score=137, Expect=6e-42]; ENSG00000198668, CALM1, calmodulin 1, [Score=137, Expect=6e-42]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=137, Expect=4e-42]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=137, Expect=4e-42]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=137, Expect=4e-42]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=137, Expect=3e-42]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=136, Expect=8e-42]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=136, Expect=6e-42]} {RNA1509_10890, RNA1509_18669, RNA1509_43138, RNA1509_48258} {RNA1310_49762.1, RNA1509_10890, RNA1509_18669, RNA1509_43138, RNA1509_48258} {RNA1509_10890, RNA1509_18669, RNA1509_43138, RNA1509_48258, RNA815_25161.1}
35. MligTC455_48955 294 6.13 Mlig455_034969

Neo: -

Age: Up-Down-Down

AGRN 0.969 - - - - 0.969 - Mlig455_034969 {REF} {Length: 2190} {Pfam: Kazal-type serine protease inhibitor domain [PF07648.17, score=130.2]; Kazal-type serine protease inhibitor domain [PF00050.23, score=96.2]} {Human: ENSG00000188157, AGRN, agrin, [Score=123, Expect=3e-29]} {Mouse: ENSMUSG00000041936, Agrn, agrin, [Score=126, Expect=2e-30]} {Dmel: FBgn0259878, Fs, Follistatin, [RH, Score=72.4, Expect=3e-13]} {Celegans: WBGene00018304, agr-1, AGRin (Synaptic protein) homolog; AGRin (Synaptic protein) homolog family member, [Score=143, Expect=2e-36]} {Smed: dd_Smed_v6_3649_0_1, dd_Smed_v6_3649_0_1, [RH, Score=201, Expect=5e-56]} {RNA1509_15340} {RNA1310_13904.1} {RNA815_7896}
36. MligTC455_30436 247 5.16 Mlig455_005917, Mlig455_007902, Mlig455_028139

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.855

0.964 - - - - 0.964 -

Mlig455_005917 {REF} {Length: 1826} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}

Mlig455_007902 {REF} {Length: 6338} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=29.0]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=27.9]} {RNA1509_25737} {RNA1310_2048} {RNA815_551.1}

Mlig455_028139 {REF} {Length: 2097} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}
37. MligTC455_38958 335 6.98 Mlig455_068315

Neo: -

Age: -

0.964 - - - - 0.964 - Mlig455_068315 {REF} {Length: 2665} {Pfam: EF-hand domain [PF13405.8, score=31.1]; EF-hand domain pair [PF13499.8, score=27.3]; EF hand [PF00036.34, score=22.7]} {Mouse: ENSMUSG00000030321, Efcab12, EF-hand calcium binding domain 12, [RH, Score=65.1, Expect=2e-10]} {Smed: dd_Smed_v6_10608_0_1, dd_Smed_v6_10608_0_1, [RH, Score=57.8, Expect=7e-10]} {RNA1509_20232} {RNA1310_17116} {RNA815_14272}
38. MligTC455_32133 781 16.27 Mlig455_051306

Neo: -

Age: logFC(26M/2M)=-0.416

Region-enriched R8: 2.021/0.00643

ANKRD63 0.96 - - - - - 0.960 Mlig455_051306 {REF} {Length: 3343} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=60.9]; Ankyrin repeats (many copies) [PF13637.8, score=56.5]; Ankyrin repeats (many copies) [PF13857.8, score=51.2]; Ankyrin repeat [PF00023.32, score=50.5]; Ankyrin repeat [PF13606.8, score=45.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=73.6, Expect=2e-13]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=71.6, Expect=5e-13]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=57.0, Expect=3e-08]} {Smed: dd_Smed_v6_11079_0_1, dd_Smed_v6_11079_0_1, [RH, Score=112, Expect=4e-27]} {RNA1509_19755} {RNA1310_3218.1} {RNA815_26964}
39. MligTC455_21297 546 11.38 Mlig455_033973

Neo: Germline

Age: Up-Down-Up

0.958 - - - - - 0.958 Mlig455_033973 {REF} {Length: 4638} {RNA1509_49102} {RNA1310_24684} {RNA815_56598}
40. MligTC455_29395 220 4.59 Mlig455_054678

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.171

0.958 - - - - 0.958 - Mlig455_054678 {REF} {Length: 1503} {NoTransDecoderORF} {RNA1509_8259} {RNA1310_23579, RNA1509_8259} {RNA1509_8259, RNA815_9835}
41. MligTC455_53189 1040 21.66 Mlig455_029623

Neo: -

Age: Down-Down-Up

0.958 - - - - - 0.958 Mlig455_029623 {REF} {Length: 1190} {Pfam: Globin [PF00042.24, score=53.3]} {Smed: dd_Smed_v6_19850_0_1, dd_Smed_v6_19850_0_1, [Score=45.4, Expect=8e-06]} {RNA1509_20726, RNA1509_38771, RNA1509_38994} {RNA1310_34513, RNA1509_20726, RNA1509_38771, RNA1509_38994} {RNA1509_20726, RNA1509_38771, RNA1509_38994, RNA815_16338}
42. MligTC455_16955 1687 35.15 Mlig455_051000

Neo: -

Age: Down-Up-Up

PLA2G7 0.957 - - - - 0.957 - Mlig455_051000 {REF} {Length: 1559} {TRANSSPLICED} {Pfam: Platelet-activating factor acetylhydrolase, isoform II [PF03403.15, score=213.8]; alpha/beta hydrolase fold [PF00561.22, score=28.3]; Alpha/beta hydrolase family [PF12697.9, score=26.6]; Serine aminopeptidase, S33 [PF12146.10, score=25.3]; Chlorophyllase enzyme [PF12740.9, score=20.4]} {Human: ENSG00000146070, PLA2G7, phospholipase A2 group VII, [RH, Score=171, Expect=1e-48]} {Mouse: ENSMUSG00000037366, Pafah2, platelet-activating factor acetylhydrolase 2, [RH, Score=163, Expect=5e-46]; ENSMUSG00000023913, Pla2g7, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), [RH, Score=158, Expect=1e-43]} {Celegans: WBGene00003906, paf-1, PAF-1; PAF-acetylhydrolase, [RH, Score=142, Expect=2e-38]} {RNA1509_16678, RNA1509_21980} {RNA1310_21439.1, RNA1509_16678, RNA1509_21980} {RNA1509_16678, RNA1509_21980, RNA815_19873}
43. MligTC455_43836 2273 47.36 Mlig455_056036, Mlig455_057471

Neo: -

Age: logFC(26M/2M)=-0.376

0.957 - - - - 0.957 -

Mlig455_056036 {REF} {Length: 2867} {RNA1509_28671} {RNA1310_6148} {RNA815_2070.1}

Mlig455_057471 {REF} {Length: 2932} {RNA1509_27859, RNA1509_28671, RNA1509_41523, RNA1509_5876} {RNA1310_6148, RNA1509_27859, RNA1509_28671, RNA1509_41523, RNA1509_5876} {RNA1509_27859, RNA1509_28671, RNA1509_41523, RNA1509_5876, RNA815_2070.1}
44. MligTC455_33387 27 0.57 Mlig455_023913, Mlig455_046500, Mlig455_057016

Neo: Int S/G2/M

Age: Up-Down-Up, logFC(26M/2M)=0.607

0.956 - - - - 0.956 -

Mlig455_023913 {REF} {Length: 4194} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.4]} {Smed: dd_Smed_v6_11577_0_1, dd_Smed_v6_11577_0_1, [Score=73.2, Expect=8e-14]} {RNA1310_77478} {RNA815_28021}

Mlig455_046500 {REF} {Length: 1944} {RNA1310_77478} {RNA815_28021}

Mlig455_057016 {REF} {Length: 2231} {RNA1310_25610.1}
45. MligTC455_52586 230 4.78 Mlig455_069158

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_069158 {REF} {Length: 3154} {RNA1509_45748, RNA1509_55217} {RNA1310_4688.1, RNA1509_45748} {RNA1509_45748, RNA815_38425}
46. MligTC455_32350 163 3.4 Mlig455_026371

Neo: -

Age: -

0.952 - - - - 0.952 - Mlig455_026371 {REF} {Length: 3693} {TRANSSPLICED} {RNA1509_10757, RNA1509_39547} {RNA1310_3174, RNA1509_39547} {RNA1509_39547, RNA815_3129}
47. MligTC455_28065 375 7.81 Mlig455_069670

Neo: -

Age: -

SHF 0.951 - - - - 0.951 - Mlig455_069670 {REF} {Length: 6323} {TRANSSPLICED} {Pfam: SH2 domain [PF00017.26, score=50.3]} {Human: ENSG00000138606, SHF, Src homology 2 domain containing F, [RH, Score=97.1, Expect=5e-21]; ENSG00000105251, SHD, Src homology 2 domain containing transforming protein D, [RH, Score=97.1, Expect=2e-21]} {Mouse: ENSMUSG00000033256, Shf, Src homology 2 domain containing F, [RH, Score=95.5, Expect=1e-20]} {Dmel: FBgn0264542, hwt, heavyweight, [RH, Score=122, Expect=1e-28]} {Celegans: WBGene00004038, plc-3, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3, [Score=51.6, Expect=1e-06]} {Smed: dd_Smed_v6_6594_0_1, dd_Smed_v6_6594_0_1, [RH, Score=116, Expect=3e-27]} {RNA1509_16431, RNA1509_23706} {RNA1310_8313, RNA1509_16431, RNA1509_23706} {RNA1509_16431, RNA1509_23706, RNA815_7976}
48. MligTC455_33802 659 13.73 Mlig455_033383

Neo: -

Age: logFC(26M/2M)=-0.359

0.951 - - - - 0.951 - Mlig455_033383 {REF} {Length: 3524} {RNA1509_14410, RNA1509_56133} {RNA1310_8398, RNA1509_56133} {RNA1509_56133, RNA815_14639}

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