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Results for MligTC455_32792

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_32792 314 6.55 Mlig455_010871

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.924/0.00688

 Mlig455_010871 {REF} {Length: 1226} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=23.1]} {Smed: dd_Smed_v6_5882_0_1, dd_Smed_v6_5882_0_1, [Score=73.9, Expect=3e-15]} {RNA1509_54110} {RNA1310_37559} {RNA815_18549}

Cumulative graph for MligTC455_32792

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -7.019 3.233 0.05250 0.53729
RegionR2 -0.184 3.233 0.90449 1.00000
RegionR3 1.098 3.233 0.18795 0.72368
RegionR4 2.924 3.233 0.00059 0.00688
RegionR5 1.102 3.233 0.19999 0.49031
RegionR6 1.464 3.233 0.06355 0.47232
RegionR7 -0.287 3.233 0.92558 1.00000
RegionR8 0.903 3.233 0.42941 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.366 3.233 1.00000 1.00000
RegenerationR2 0.875 3.233 0.09111 0.48285
RegenerationR3 -0.535 3.233 0.35501 0.77340
RegenerationR4 -0.654 3.233 0.29042 0.73446
RegenerationR5 -0.259 3.233 0.66205 0.93691
RegenerationR6 -1.157 3.233 0.06549 0.32135
RegenerationBL -1.54 3.233 0.07267 0.31419
RegenerationTP -1.729 3.233 0.07628 0.44186


Genes with expression patterns similar to MligTC455_32792

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_32792 314 6.55 Mlig455_010871

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.924/0.00688

 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_010871 {REF} {Length: 1226} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=23.1]} {Smed: dd_Smed_v6_5882_0_1, dd_Smed_v6_5882_0_1, [Score=73.9, Expect=3e-15]} {RNA1509_54110} {RNA1310_37559} {RNA815_18549}
2. MligTC455_22226 219 4.55 Mlig455_056124

Neo: -

Age: -

 DNAH12 4.238 0.787 0.816 - 0.965 0.824 0.846 Mlig455_056124 {REF} {Length: 12587} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=508.4]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=465.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=385.3]; P-loop containing dynein motor region D4 [PF12780.9, score=347.2]; ATP-binding dynein motor region [PF12781.9, score=299.3]; P-loop containing dynein motor region [PF12775.9, score=276.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=192.4]; Microtubule-binding stalk of dynein motor [PF12777.9, score=176.8]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=153.9]; Dynein heavy chain AAA lid domain [PF17852.3, score=118.0]; AAA domain (dynein-related subfamily) [PF07728.16, score=76.5]; AAA+ lid domain [PF17857.3, score=60.1]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=36.0]; AAA domain [PF13401.8, score=21.7]; RNA helicase [PF00910.24, score=20.4]} {Human: ENSG00000174844, DNAH12, dynein axonemal heavy chain 12, [RH, Score=5023, Expect=0.0]} {Mouse: ENSMUSG00000021879, Dnah12, dynein, axonemal, heavy chain 12, [RH, Score=5006, Expect=0.0]; ENSMUSG00000116451, Dnah12, dynein, axonemal, heavy chain 12, [RH, Score=5006, Expect=0.0]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [RH, Score=3675, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=1005, Expect=0.0]} {Smed: dd_Smed_v6_6941_0_1, dd_Smed_v6_6941_0_1, [RH, Score=5650, Expect=0.0]} {RNA1509_306, RNA1509_4980} {RNA1310_68.1, RNA1509_306, RNA1509_4980} {RNA1509_306, RNA1509_4980, RNA815_82}
3. MligTC455_50366 4401 91.69 Mlig455_031856, Mlig455_031942

Neo: -

Age: logFC(26M/2M)=-0.385

Region-enriched R2: 1.195/0.00796

 CFAP100 2.658 - - - 0.908 0.959 0.791

Mlig455_031856 {REF} {Length: 2306} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4200) [PF13863.8, score=102.4]} {Human: ENSG00000163885, CFAP100, cilia and flagella associated protein 100, [RH, Score=363, Expect=3e-117]} {Mouse: ENSMUSG00000048794, Cfap100, cilia and flagella associated protein 100, [RH, Score=357, Expect=6e-115]} {Smed: dd_Smed_v6_6518_0_1, dd_Smed_v6_6518_0_1, [RH, Score=466, Expect=2e-158]} {RNA1509_2849, RNA1509_9395} {RNA1310_12917.1, RNA1509_2849} {RNA1509_2849, RNA815_2819}

Mlig455_031942 {REF} {Length: 2061} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4200) [PF13863.8, score=102.4]} {Human: ENSG00000163885, CFAP100, cilia and flagella associated protein 100, [RH, Score=363, Expect=3e-117]} {Mouse: ENSMUSG00000048794, Cfap100, cilia and flagella associated protein 100, [RH, Score=357, Expect=6e-115]} {Smed: dd_Smed_v6_6518_0_1, dd_Smed_v6_6518_0_1, [RH, Score=466, Expect=2e-158]} {RNA1509_2849} {RNA1310_12917.1} {RNA815_2819}
4. MligTC455_47171 125 2.61 Mlig455_027708

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.385/0.02638

 TCF7L2 2.655 - - - 0.769 0.959 0.927 Mlig455_027708 {REF} {Length: 4153} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=75.0]; HMG-box domain [PF09011.12, score=30.1]} {Human: ENSG00000148737, TCF7L2, transcription factor 7 like 2, [RH, Score=189, Expect=1e-50]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=185, Expect=4e-50]} {Mouse: ENSMUSG00000024985, Tcf7l2, transcription factor 7 like 2, T cell specific, HMG box, [Score=187, Expect=9e-50]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=188, Expect=2e-49]} {Celegans: WBGene00004077, pop-1, [RH, Score=118, Expect=4e-28]} {Smed: dd_Smed_v6_8152_0_1, dd_Smed_v6_8152_0_1, [RH, Score=193, Expect=4e-52]} {RNA1509_7090} {RNA1310_2735.1} {RNA815_5131}
5. MligTC455_30436 247 5.16 Mlig455_005917, Mlig455_007902, Mlig455_028139

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.855

 2.577 0.894 - 0.733 - 0.950 -

Mlig455_005917 {REF} {Length: 1826} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}

Mlig455_007902 {REF} {Length: 6338} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=29.0]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=27.9]} {RNA1509_25737} {RNA1310_2048} {RNA815_551.1}

Mlig455_028139 {REF} {Length: 2097} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}
6. MligTC455_22227 515 10.73 Mlig455_058769

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.108/0.00122

 DNAH12 2.53 - - - 0.952 0.819 0.759 Mlig455_058769 {REF} {Length: 12537} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=508.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=470.5]; P-loop containing dynein motor region D4 [PF12780.9, score=347.5]; ATP-binding dynein motor region [PF12781.9, score=299.5]; P-loop containing dynein motor region [PF12775.9, score=276.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=177.0]; Dynein heavy chain AAA lid domain [PF18198.3, score=162.7]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=154.2]; Dynein heavy chain AAA lid domain [PF17852.3, score=118.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=77.7]; AAA+ lid domain [PF17857.3, score=60.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=36.8]; AAA domain [PF13401.8, score=22.2]; RNA helicase [PF00910.24, score=21.0]; AAA ATPase domain [PF13191.8, score=19.9]} {Human: ENSG00000174844, DNAH12, dynein axonemal heavy chain 12, [Score=4450, Expect=0.0]} {Mouse: ENSMUSG00000116451, Dnah12, dynein, axonemal, heavy chain 12, [Score=4459, Expect=0.0]; ENSMUSG00000021879, Dnah12, dynein, axonemal, heavy chain 12, [Score=4459, Expect=0.0]} {Dmel: FBgn0013810, Dhc36C, Dynein heavy chain at 36C, [Score=3239, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=968, Expect=0.0]} {Smed: dd_Smed_v6_6941_0_1, dd_Smed_v6_6941_0_1, [Score=4988, Expect=0.0]} {RNA1509_306} {RNA1310_68.1} {RNA815_82}
7. MligTC455_27220 3965 82.6 Mlig455_007059

Neo: -

Age: logFC(26M/2M)=-0.158

 TEKT2 2.361 - - 0.706 0.704 - 0.951 Mlig455_007059 {REF} {Length: 2591} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=425.6]} {Human: ENSG00000092850, TEKT2, tektin 2, [RH, Score=421, Expect=5e-145]} {Mouse: ENSMUSG00000028845, Tekt2, tektin 2, [RH, Score=387, Expect=4e-132]} {Dmel: FBgn0034816, CG3085, [RH, Score=213, Expect=2e-64]} {Celegans: WBGene00019828, R02E12.4, [Score=78.2, Expect=2e-15]} {Smed: dd_Smed_v6_2339_0_1, dd_Smed_v6_2339_0_1, [RH, Score=543, Expect=0.0]} {RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859} {RNA1310_13089.2, RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859} {RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859, RNA815_4479}
8. MligTC455_41632 1020 21.26 Mlig455_031169

Neo: -

Age: -

 IQUB 1.903 - - - 0.972 - 0.931 Mlig455_031169 {REF} {Length: 3147} {TRANSSPLICED} {Pfam: Ubiquitin family [PF00240.25, score=29.5]} {Human: ENSG00000164675, IQUB, IQ motif and ubiquitin domain containing, [RH, Score=582, Expect=0.0]} {Mouse: ENSMUSG00000046192, Iqub, IQ motif and ubiquitin domain containing, [RH, Score=545, Expect=0.0]} {Dmel: FBgn0038960, CG13855, [RH, Score=241, Expect=2e-68]} {Smed: dd_Smed_v6_9227_0_1, dd_Smed_v6_9227_0_1, [RH, Score=585, Expect=0.0]} {RNA1509_27336, RNA1509_6305} {RNA1310_4747.1, RNA1509_27336, RNA1509_6305} {RNA1509_27336, RNA1509_6305, RNA815_1419.1}
9. MligTC455_12985 171 3.57 Mlig455_052961

Neo: -

Age: -

 LOXHD1 1.884 - - - - 0.931 0.953 Mlig455_052961 {REF} {Length: 4152} {Pfam: PLAT/LH2 domain [PF01477.25, score=111.3]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=91.3, Expect=1e-17]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=87.8, Expect=8e-17]} {Smed: dd_Smed_v6_10460_0_1, dd_Smed_v6_10460_0_1, [Score=102, Expect=8e-22]} {RNA1509_6796} {RNA1310_2867.1} {RNA815_966}
10. MligTC455_25566 133 2.77 Mlig455_013513

Neo: -

Age: logFC(26M/2M)=-0.283

 ANKAR 1.837 0.881 - - - - 0.956 Mlig455_013513 {REF} {Length: 4806} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=53.6]; Ankyrin repeats (many copies) [PF13857.8, score=25.9]; Ankyrin repeats (3 copies) [PF12796.9, score=22.4]; Ankyrin repeats (many copies) [PF13637.8, score=19.3]} {Human: ENSG00000151687, ANKAR, ankyrin and armadillo repeat containing, [Score=265, Expect=1e-73]} {Mouse: ENSMUSG00000039342, Ankar, ankyrin and armadillo repeat containing, [Score=292, Expect=3e-83]} {Smed: dd_Smed_v6_10062_0_1, dd_Smed_v6_10062_0_1, [RH, Score=450, Expect=1e-144]} {RNA1509_10980} {RNA1310_5551, RNA1509_10980} {RNA1509_10980, RNA815_1615}
11. MligTC455_46735 771 16.07 Mlig455_028901

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.417

 1.737 - - - 0.786 - 0.951 Mlig455_028901 {REF} {Length: 1588} {RNA1509_17335, RNA1509_37656, RNA1509_56516} {RNA1310_10469, RNA1509_17335, RNA1509_37656, RNA1509_56516} {RNA1509_17335, RNA1509_37656, RNA1509_56516, RNA815_8784.1}
12. MligTC455_28827 979 20.4 Mlig455_044793

Neo: -

Age: -

 PTPRD 1.735 - - - 0.783 0.952 - Mlig455_044793 {REF} {Length: 5656} {TRANSSPLICED} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=74.6]; Fibronectin type III domain [PF00041.23, score=72.1]} {Human: ENSG00000153707, PTPRD, protein tyrosine phosphatase, receptor type D, [Score=120, Expect=6e-27]; ENSG00000282932, PTPRD, protein tyrosine phosphatase, receptor type D, [Score=120, Expect=6e-27]; ENSG00000196090, PTPRT, protein tyrosine phosphatase, receptor type T, [Score=118, Expect=3e-26]} {Mouse: ENSMUSG00000028399, Ptprd, protein tyrosine phosphatase, receptor type, D, [Score=120, Expect=4e-27]; ENSMUSG00000053141, Ptprt, protein tyrosine phosphatase, receptor type, T, [Score=117, Expect=4e-26]} {Dmel: FBgn0004369, Ptp99A, Protein tyrosine phosphatase 99A, [Score=92.4, Expect=1e-18]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=70.1, Expect=7e-12]} {Smed: dd_Smed_v6_13361_0_1, dd_Smed_v6_13361_0_1, [Score=75.5, Expect=1e-13]} {RNA1509_2576} {RNA1310_671.1} {RNA815_239}
13. MligTC455_53608 2624 54.66 Mlig455_066346

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=2.900

 SPAG6 1.727 - - - 0.767 - 0.960 Mlig455_066346 {REF} {Length: 1967} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=130.5]; HEAT repeats [PF13646.8, score=55.3]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=52.1]; HEAT repeat [PF02985.24, score=50.8]; HEAT-like repeat [PF13513.8, score=35.3]; Adaptin N terminal region [PF01602.22, score=31.7]; C-terminal domain of two-partite extracellular sensor domain [PF17150.6, score=31.5]; DNA alkylation repair enzyme [PF08713.13, score=30.7]; Proteasome non-ATPase 26S subunit [PF10508.11, score=24.4]; Rapamycin-insensitive companion of mTOR, N-term [PF14664.8, score=19.6]} {Human: ENSG00000077327, SPAG6, sperm associated antigen 6, [RH, Score=863, Expect=0.0]} {Mouse: ENSMUSG00000022783, Spag6l, sperm associated antigen 6-like, [RH, Score=881, Expect=0.0]} {Dmel: FBgn0024889, Kap-alpha1, karyopherin alpha1, [Score=65.5, Expect=5e-11]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [Score=70.9, Expect=8e-13]} {Smed: dd_Smed_v6_3991_0_1, dd_Smed_v6_3991_0_1, [RH, Score=894, Expect=0.0]} {RNA1509_1649} {RNA1310_12357} {RNA815_5582.1}
14. MligTC455_43622 176 3.67 Mlig455_025727

Neo: -

Age: -

 1.72 - - 0.747 - - 0.973 Mlig455_025727 {REF} {Length: 2693} {Pfam: CAP-Gly domain [PF01302.27, score=18.9]} {RNA1509_50338} {RNA1310_25031} {RNA815_24211}
15. MligTC455_46558 1383 28.82 Mlig455_031428

Neo: -

Age: -

Regeneration-downregulated TP: -1.779

Regeneration-depleted TP: -1.779

 TANC1 1.706 - - - 0.742 0.964 - Mlig455_031428 {REF} {Length: 2092} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=49.3]; Ankyrin repeats (many copies) [PF13857.8, score=47.2]; Ankyrin repeat [PF13606.8, score=41.6]; Ankyrin repeats (many copies) [PF13637.8, score=36.2]; Ankyrin repeat [PF00023.32, score=36.1]} {Human: ENSG00000115183, TANC1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=55.5, Expect=1e-07]; ENSG00000145362, ANK2, ankyrin 2, [Score=53.5, Expect=7e-07]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=52.0, Expect=1e-06]; ENSMUSG00000005251, Ripk4, receptor-interacting serine-threonine kinase 4, [Score=51.6, Expect=1e-06]; ENSMUSG00000035168, Tanc1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=50.4, Expect=3e-06]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=55.8, Expect=6e-08]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=50.4, Expect=2e-06]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [Score=52.0, Expect=3e-07]} {RNA1509_19702, RNA1509_30097} {RNA1310_14830, RNA1509_19702, RNA1509_30097} {RNA1509_19702, RNA1509_30097, RNA815_5101}
16. MligTC455_23642 573 11.93 Mlig455_069008

Neo: -

Age: logFC(26M/2M)=0.738

 ACTB 1.694 - - - 0.742 0.952 - Mlig455_069008 {REF} {Length: 2243} {Pfam: Actin [PF00022.21, score=267.5]; Protein kinase domain [PF00069.27, score=203.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=20.5]} {Human: ENSG00000075624, ACTB, actin beta, [Score=417, Expect=3e-141]; ENSG00000184009, ACTG1, actin gamma 1, [Score=417, Expect=5e-141]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=4e-136]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=5e-136]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [Score=403, Expect=2e-135]; ENSG00000169067, ACTBL2, actin, beta like 2, [Score=401, Expect=9e-135]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [Score=400, Expect=1e-134]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [Score=417, Expect=4e-141]; ENSMUSG00000029580, Actb, actin, beta, [Score=417, Expect=2e-141]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=2e-136]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=4e-136]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [Score=404, Expect=5e-136]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [Score=403, Expect=1e-135]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [Score=400, Expect=8e-135]} {Dmel: FBgn0000042, Act5C, Actin 5C, [Score=417, Expect=3e-141]} {Celegans: WBGene00000064, act-2, Actin-2, [Score=418, Expect=6e-142]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [Score=419, Expect=4e-142]} {RNA1509_28185} {RNA1310_11665} {RNA815_6928}
17. MligTC455_53434 3228 67.25 Mlig455_028543

Neo: -

Age: logFC(26M/2M)=-0.260

 RSPH4A 1.687 - - - 0.736 0.951 - Mlig455_028543 {REF} {Length: 2028} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=618.3]} {Human: ENSG00000111834, RSPH4A, radial spoke head component 4A, [RH, Score=441, Expect=1e-147]} {Mouse: ENSMUSG00000039552, Rsph4a, radial spoke head 4 homolog A (Chlamydomonas), [Score=447, Expect=6e-150]} {Dmel: FBgn0034957, CG3121, [Score=227, Expect=6e-66]} {Smed: dd_Smed_v6_5346_0_1, dd_Smed_v6_5346_0_1, [RH, Score=456, Expect=2e-156]} {RNA1509_18862, RNA1509_6840, RNA1509_800} {RNA1310_12717.1, RNA1509_18862, RNA1509_6840, RNA1509_800} {RNA1509_18862, RNA1509_6840, RNA1509_800, RNA815_4800.1}
18. MligTC455_29902 134 2.79 Mlig455_036021

Neo: -

Age: Down-Up-Up

 MAP3K4 1.67 - 0.716 - 0.954 - - Mlig455_036021 {REF} {Length: 1657} {Pfam: Protein kinase domain [PF00069.27, score=164.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=127.0]; Fungal protein kinase [PF17667.3, score=29.9]; Phosphotransferase enzyme family [PF01636.25, score=20.6]; ABC1 atypical kinase-like domain [PF03109.18, score=20.2]; Kinase-like [PF14531.8, score=18.2]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=130, Expect=1e-32]} {Mouse: ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=126, Expect=3e-31]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=125, Expect=7e-31]; ENSMUSG00000071369, Map3k5, mitogen-activated protein kinase kinase kinase 5, [Score=122, Expect=5e-30]; ENSMUSG00000031303, Map3k15, mitogen-activated protein kinase kinase kinase 15, [Score=122, Expect=5e-30]} {Dmel: FBgn0024329, Mekk1, [Score=127, Expect=7e-32]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=135, Expect=8e-35]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=113, Expect=4e-27]} {RNA1509_43621} {RNA1310_32013} {RNA815_6977.1}
19. MligTC455_35663 475 9.89 Mlig455_028426

Neo: -

Age: -

 CLHC1 0.972 - - - - 0.972 - Mlig455_028426 {REF} {Length: 1005} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.3]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [RH, Score=155, Expect=8e-40]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [RH, Score=160, Expect=8e-42]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=51.2, Expect=2e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [RH, Score=145, Expect=4e-37]} {RNA1509_25530} {RNA1310_5794.1} {RNA815_1706}
20. MligTC455_03719 3498 72.86 Mlig455_015750

Neo: Irradiation

Age: -

 0.971 - - - - 0.971 - Mlig455_015750 {REF} {Length: 2548} {TRANSSPLICED} {RNA1509_54771, RNA1509_5768} {RNA1310_11683, RNA1509_54771, RNA1509_5768} {RNA1509_54771, RNA1509_5768, RNA815_11103}
21. MligTC455_46249 6782 141.28 Mlig455_000078, Mlig455_063745

Neo: -

Age: logFC(26M/2M)=-0.255

 IQCG 0.965 - - - 0.965 - -

Mlig455_000078 {REF} {Length: 1481} {Human: ENSG00000114473, IQCG, IQ motif containing G, [Score=120, Expect=5e-31]} {Mouse: ENSMUSG00000035578, Iqcg, IQ motif containing G, [Score=127, Expect=1e-33]} {Smed: dd_Smed_v6_7221_0_1, dd_Smed_v6_7221_0_1, [Score=207, Expect=9e-65]} {RNA1509_16596, RNA1509_36158} {RNA1310_23185.1, RNA1509_16596} {RNA1509_16596, RNA815_9625.1}

Mlig455_063745 {REF} {Length: 1474} {Human: ENSG00000114473, IQCG, IQ motif containing G, [RH, Score=202, Expect=2e-60]} {Mouse: ENSMUSG00000035578, Iqcg, IQ motif containing G, [RH, Score=209, Expect=2e-63]} {Smed: dd_Smed_v6_7221_0_1, dd_Smed_v6_7221_0_1, [RH, Score=317, Expect=3e-106]} {RNA1509_17815, RNA1509_2529, RNA1509_36158, RNA1509_8663} {RNA1310_23185.1, RNA1509_17815, RNA1509_2529, RNA1509_36158, RNA1509_8663} {RNA1509_17815, RNA1509_2529, RNA1509_36158, RNA1509_8663, RNA815_9625.1}
22. MligTC455_41980 1108 23.09 Mlig455_048223

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.452

Regeneration-depleted BL: -2.044
Regeneration-depleted R6: -1.918

 0.958 - - - - 0.958 - Mlig455_048223 {REF} {Length: 1924} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_5489} {RNA1310_15598} {RNA815_10198.1}
23. MligTC455_47173 255 5.32 Mlig455_047769

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.081/0.00565

 TCF7L2 0.958 - - - 0.958 - - Mlig455_047769 {REF} {Length: 4480} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=75.0]; HMG-box domain [PF09011.12, score=30.1]} {Human: ENSG00000148737, TCF7L2, transcription factor 7 like 2, [RH, Score=190, Expect=1e-50]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=188, Expect=5e-51]} {Mouse: ENSMUSG00000024985, Tcf7l2, transcription factor 7 like 2, T cell specific, HMG box, [Score=187, Expect=5e-50]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=189, Expect=8e-50]} {Celegans: WBGene00004077, pop-1, [RH, Score=120, Expect=1e-28]} {Smed: dd_Smed_v6_8152_0_1, dd_Smed_v6_8152_0_1, [RH, Score=194, Expect=2e-52]} {RNA1509_59103, RNA1509_7090} {RNA1310_2735.1, RNA1509_59103} {RNA1509_59103, RNA815_5131}
24. MligTC455_42421 451 9.4 Mlig455_014113

Neo: -

Age: -

 0.957 - 0.957 - - - - Mlig455_014113 {REF} {Length: 3365} {RNA1509_22432} {RNA1310_7691.1, RNA1509_22432} {RNA1509_22432, RNA815_2712.1}
25. MligTC455_31714 192 4.01 Mlig455_025637

Neo: -

Age: -

 WDR47 0.953 - - - - - 0.953 Mlig455_025637 {REF} {Length: 4092} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=85.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=44.4]} {Human: ENSG00000085433, WDR47, WD repeat domain 47, [RH, Score=305, Expect=4e-88]} {Mouse: ENSMUSG00000040389, Wdr47, WD repeat domain 47, [RH, Score=310, Expect=4e-90]} {Dmel: FBgn0034931, CG2812, [RH, Score=278, Expect=1e-84]} {Celegans: WBGene00019434, nmtn-1, NeMiTiN (Neuronal enriched MAP interacting protein) homolog, [RH, Score=300, Expect=1e-86]} {Smed: dd_Smed_v6_3366_0_2, dd_Smed_v6_3366_0_2, [RH, Score=331, Expect=4e-98]} {RNA1509_17472} {RNA1310_5088} {RNA815_16975}
26. MligTC455_47822 424 8.84 Mlig455_001731

Neo: -

Age: -

 PRKCB 0.953 - - - - 0.953 - Mlig455_001731 {REF} {Length: 5462} {Pfam: Protein kinase domain [PF00069.27, score=217.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=127.3]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=117.0]; C2 domain [PF00168.32, score=99.0]; Protein kinase C terminal domain [PF00433.26, score=34.8]} {Human: ENSG00000166501, PRKCB, protein kinase C beta, [RH, Score=993, Expect=0.0]; ENSG00000154229, PRKCA, protein kinase C alpha, [RH, Score=982, Expect=0.0]} {Mouse: ENSMUSG00000052889, Prkcb, protein kinase C, beta, [RH, Score=991, Expect=0.0]; ENSMUSG00000050965, Prkca, protein kinase C, alpha, [RH, Score=983, Expect=0.0]} {Dmel: FBgn0003091, Pkc53E, Protein C kinase 53E, [RH, Score=988, Expect=0.0]} {Celegans: WBGene00004033, pkc-2, Protein kinase C-like 2, [RH, Score=956, Expect=0.0]} {Smed: dd_Smed_v6_4244_0_2, dd_Smed_v6_4244_0_2, [RH, Score=1076, Expect=0.0]} {RNA1509_11086} {RNA1310_10368.1} {RNA815_2108.1}
27. MligTC455_19760 6101 127.11 Mlig455_004980, Mlig455_005294

Neo: -

Age: logFC(26M/2M)=-0.196

 DNAI1 0.952 - - - - 0.952 -

Mlig455_004980 {REF} {Length: 2735} {Pfam: WD domain, G-beta repeat [PF00400.34, score=34.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.3]} {Human: ENSG00000122735, DNAI1, dynein axonemal intermediate chain 1, [RH, Score=773, Expect=0.0]} {Mouse: ENSMUSG00000061322, Dnaic1, dynein, axonemal, intermediate chain 1, [RH, Score=773, Expect=0.0]} {Dmel: FBgn0034566, CG9313, [RH, Score=522, Expect=1e-176]} {Celegans: WBGene00015927, dyci-1, DYnein Chain, light Intermediate, [Score=112, Expect=9e-26]} {Smed: dd_Smed_v6_4753_0_1, dd_Smed_v6_4753_0_1, [RH, Score=858, Expect=0.0]} {RNA1509_16663, RNA1509_31620, RNA1509_34544, RNA1509_36463, RNA1509_40409, RNA1509_41706, RNA1509_51014} {RNA1310_13300.1, RNA1509_16663, RNA1509_31620, RNA1509_34544, RNA1509_36463, RNA1509_40409, RNA1509_41706} {RNA1509_16663, RNA1509_31620, RNA1509_34544, RNA1509_36463, RNA1509_40409, RNA1509_41706, RNA815_2412.1}

Mlig455_005294 {REF} {Length: 2692} {Pfam: WD domain, G-beta repeat [PF00400.34, score=34.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.5]} {Human: ENSG00000122735, DNAI1, dynein axonemal intermediate chain 1, [RH, Score=772, Expect=0.0]} {Mouse: ENSMUSG00000061322, Dnaic1, dynein, axonemal, intermediate chain 1, [RH, Score=772, Expect=0.0]} {Dmel: FBgn0034566, CG9313, [RH, Score=525, Expect=6e-178]} {Celegans: WBGene00015927, dyci-1, DYnein Chain, light Intermediate, [Score=112, Expect=9e-26]} {Smed: dd_Smed_v6_4753_0_1, dd_Smed_v6_4753_0_1, [RH, Score=860, Expect=0.0]} {RNA1509_51014} {RNA1310_13300.1} {RNA815_2412.1}
28. MligTC455_37382 804 16.75 Mlig455_045573

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.463

 CYP3A5 0.952 - - - 0.952 - - Mlig455_045573 {REF} {Length: 1950} {Pfam: Cytochrome P450 [PF00067.24, score=302.6]} {Human: ENSG00000106258, CYP3A5, cytochrome P450 family 3 subfamily A member 5, [Score=266, Expect=2e-82]; ENSG00000282301, CYP3A7-CYP3A51P, CYP3A7-CYP3A51P readthrough, [Score=255, Expect=7e-78]; ENSG00000160870, CYP3A7, cytochrome P450 family 3 subfamily A member 7, [Score=255, Expect=2e-78]; ENSG00000160868, CYP3A4, cytochrome P450 family 3 subfamily A member 4, [Score=254, Expect=5e-78]} {Mouse: ENSMUSG00000029727, Cyp3a13, cytochrome P450, family 3, subfamily a, polypeptide 13, [Score=277, Expect=4e-87]; ENSMUSG00000075551, Cyp3a41a, cytochrome P450, family 3, subfamily a, polypeptide 41A, [Score=266, Expect=1e-82]; ENSMUSG00000075552, Cyp3a41b, cytochrome P450, family 3, subfamily a, polypeptide 41B, [Score=266, Expect=1e-82]} {Dmel: FBgn0000473, Cyp6a2, Cytochrome P450-6a2, [Score=222, Expect=4e-66]} {Celegans: WBGene00011676, cyp-13A2, Putative cytochrome P450 CYP13A2, [RH, Score=229, Expect=1e-68]} {Smed: dd_Smed_v6_4319_0_1, dd_Smed_v6_4319_0_1, [RH, Score=327, Expect=1e-106]} {RNA1509_15610, RNA1509_34868} {RNA1310_14317, RNA1509_15610, RNA1509_34868} {RNA1509_15610, RNA1509_34868, RNA815_5514}
29. MligTC455_53501 350 7.29 Mlig455_037470

Neo: -

Age: -

 IFT22 0.951 - - - - - 0.951 Mlig455_037470 {REF} {Length: 910} {Pfam: Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=42.7]; Ras family [PF00071.24, score=36.8]; ADP-ribosylation factor family [PF00025.23, score=35.3]; Signal recognition particle receptor beta subunit [PF09439.12, score=20.4]} {Human: ENSG00000128581, IFT22, intraflagellar transport 22, [RH, Score=148, Expect=5e-45]} {Mouse: ENSMUSG00000007987, Ift22, intraflagellar transport 22, [RH, Score=139, Expect=8e-42]} {Celegans: WBGene00012132, ifta-2, Intraflagellar transport associated protein 2, [RH, Score=95.9, Expect=2e-24]} {Smed: dd_Smed_v6_11176_0_1, dd_Smed_v6_11176_0_1, [RH, Score=213, Expect=4e-71]} {RNA1509_53245} {RNA1310_41419} {RNA815_20100}
30. MligTC455_16046 633 13.18 Mlig455_022748

Neo: -

Age: Down-Up-Down

 CDYL 0.95 - - - - 0.950 - Mlig455_022748 {REF} {Length: 8355} {TRANSSPLICED} {Pfam: Chromo (CHRromatin Organisation MOdifier) domain [PF00385.26, score=46.1]; Ankyrin repeats (3 copies) [PF12796.9, score=27.1]; Ankyrin repeat [PF13606.8, score=21.5]} {Human: ENSG00000153046, CDYL, chromodomain Y like, [Score=56.2, Expect=7e-08]; ENSG00000196199, MPHOSPH8, M-phase phosphoprotein 8, [Score=53.9, Expect=5e-07]} {Mouse: ENSMUSG00000031758, Cdyl2, chromodomain protein, Y chromosome-like 2, [Score=53.5, Expect=3e-07]; ENSMUSG00000059288, Cdyl, chromodomain protein, Y chromosome-like, [Score=52.4, Expect=7e-07]; ENSMUSG00000079184, Mphosph8, M-phase phosphoprotein 8, [Score=52.4, Expect=9e-07]} {Dmel: FBgn0004400, rhi, rhino, [Score=52.0, Expect=6e-07]} {Smed: dd_Smed_v6_8960_0_1, dd_Smed_v6_8960_0_1, [Score=60.5, Expect=1e-09]} {RNA1509_12680, RNA1509_39952} {RNA1310_20959.1, RNA1509_39952} {RNA1509_39952, RNA815_8097}
31. MligTC455_35664 1772 36.91 Mlig455_020393, Mlig455_028392, Mlig455_058437

Neo: -

Age: logFC(26M/2M)=-0.217

Region-enriched R4: 1.033/0.04115

 CLHC1 0.95 - - - - 0.950 -

Mlig455_020393 {REF} {Length: 1999} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.3]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [RH, Score=155, Expect=8e-40]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [RH, Score=160, Expect=8e-42]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=51.2, Expect=2e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [RH, Score=145, Expect=4e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_028392 {REF} {Length: 1994} {TRANSSPLICED} {Pfam: Clathrin-H-link [PF13838.8, score=35.7]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=110, Expect=4e-25]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [Score=54.7, Expect=3e-07]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.4, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=114, Expect=1e-26]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_058437 {REF} {Length: 2088} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.4]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=153, Expect=3e-39]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [Score=158, Expect=4e-41]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.8, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=144, Expect=9e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}
32. MligTC455_36317 545 11.35 Mlig455_025049

Neo: -

Age: -

 GLB1 0.95 - - - - 0.950 - Mlig455_025049 {REF} {Length: 2498} {Pfam: Glycosyl hydrolases family 35 [PF01301.21, score=364.2]; Beta-galactosidase [PF02449.17, score=40.5]; Beta-galactosidase jelly roll domain [PF13364.8, score=31.4]} {Human: ENSG00000170266, GLB1, galactosidase beta 1, [RH, Score=482, Expect=1e-161]} {Mouse: ENSMUSG00000045594, Glb1, galactosidase, beta 1, [RH, Score=491, Expect=1e-165]} {Dmel: FBgn0001089, Gal, beta galactosidase, [RH, Score=412, Expect=7e-135]} {Celegans: WBGene00011832, bgal-1, Beta-galactosidase, [RH, Score=384, Expect=1e-124]} {Smed: dd_Smed_v6_4056_0_1, dd_Smed_v6_4056_0_1, [RH, Score=514, Expect=4e-175]} {RNA1509_37267} {RNA1310_9080.2, RNA1509_37267} {RNA1509_37267, RNA815_6506}
33. MligTC455_45148 212 4.41 Mlig455_027575

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.513

 0.95 - - - - - 0.950 Mlig455_027575 {REF} {Length: 3134} {Pfam: Prominin [PF05478.13, score=19.5]} {RNA1509_42069} {RNA1310_6083, RNA1509_42069} {RNA1509_42069, RNA815_5815}
34. MligTC455_53512 916 19.08 Mlig455_028726

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.315

Region-enriched R2: 1.504/0.01018

 IFT172 0.95 - - - - 0.950 - Mlig455_028726 {REF} {Length: 2813} {Pfam: Region in Clathrin and VPS [PF00637.22, score=23.3]; Tetratricopeptide repeat [PF13176.8, score=19.3]} {Human: ENSG00000138002, IFT172, intraflagellar transport 172, [Score=871, Expect=0.0]} {Mouse: ENSMUSG00000038564, Ift172, intraflagellar transport 172, [Score=873, Expect=0.0]} {Dmel: FBgn0035317, Oseg2, Outer segment 2, [Score=546, Expect=5e-173]} {Celegans: WBGene00003883, osm-1, Intraflagellar transport protein osm-1, [Score=517, Expect=2e-162]} {Smed: dd_Smed_v6_10638_0_1, dd_Smed_v6_10638_0_1, [Score=615, Expect=0.0]} {RNA1509_2378} {RNA1310_994} {RNA815_250}

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