Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_49552 | 1383 | 28.82 | Mlig455_049932 | Neo: - Age: - |
MAP3K19 | Mlig455_049932 {REF} {Length: 4789} {Pfam: Protein kinase domain [PF00069.27, score=149.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=131.1]; Caspase domain [PF00656.24, score=120.9]; Ankyrin repeats (3 copies) [PF12796.9, score=69.7]; Ankyrin repeats (many copies) [PF13857.8, score=55.5]; Ankyrin repeat [PF00023.32, score=42.8]; Ankyrin repeats (many copies) [PF13637.8, score=41.0]; Ankyrin repeat [PF13606.8, score=39.6]; Fungal protein kinase [PF17667.3, score=18.8]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=126, Expect=1e-29]; ENSG00000060237, WNK1, WNK lysine deficient protein kinase 1, [Score=120, Expect=8e-27]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=120, Expect=5e-28]; ENSMUSG00000045962, Wnk1, WNK lysine deficient protein kinase 1, [Score=120, Expect=5e-27]; ENSMUSG00000041245, Wnk3, WNK lysine deficient protein kinase 3, [Score=116, Expect=3e-26]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=109, Expect=5e-24]} {Celegans: WBGene00006941, wnk-1, Serine/threonine-protein kinase WNK, [Score=106, Expect=7e-23]} {Smed: dd_Smed_v6_2030_0_14, dd_Smed_v6_2030_0_14, [Score=104, Expect=2e-23]} {RNA1509_2733, RNA1509_55677} {RNA1310_1474, RNA1509_2733, RNA1509_55677} {RNA1509_2733, RNA1509_55677, RNA815_848} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.666 | 4.948 | 0.33797 | 0.98402 | |
RegionR2 | -0.466 | 4.948 | 0.24794 | 0.62547 | |
RegionR3 | -0.238 | 4.948 | 0.48346 | 0.98453 | |
RegionR4 | 0.501 | 4.948 | 0.20971 | 0.49397 | |
RegionR5 | -0.341 | 4.948 | 0.31231 | 0.65121 | |
RegionR6 | -0.208 | 4.948 | 0.54884 | 1.00000 | |
RegionR7 | -0.219 | 4.948 | 0.58036 | 1.00000 | |
RegionR8 | 0.306 | 4.948 | 0.48592 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -2.979 | 4.948 | 0.02205 | 0.58499 | |
RegenerationR2 | -0.155 | 4.948 | 0.69592 | 0.95507 | |
RegenerationR3 | -0.609 | 4.948 | 0.15163 | 0.58100 | |
RegenerationR4 | -1.037 | 4.948 | 0.01578 | 0.19624 | |
RegenerationR5 | -0.51 | 4.948 | 0.22174 | 0.65647 | |
RegenerationR6 | -0.478 | 4.948 | 0.27533 | 0.62476 | |
RegenerationBL | -0.733 | 4.948 | 0.09845 | 0.36863 | |
RegenerationTP | -0.291 | 4.948 | 0.52247 | 0.91529 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_49552 | 1383 | 28.82 | Mlig455_049932 | Neo: - Age: - |
MAP3K19 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_049932 {REF} {Length: 4789} {Pfam: Protein kinase domain [PF00069.27, score=149.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=131.1]; Caspase domain [PF00656.24, score=120.9]; Ankyrin repeats (3 copies) [PF12796.9, score=69.7]; Ankyrin repeats (many copies) [PF13857.8, score=55.5]; Ankyrin repeat [PF00023.32, score=42.8]; Ankyrin repeats (many copies) [PF13637.8, score=41.0]; Ankyrin repeat [PF13606.8, score=39.6]; Fungal protein kinase [PF17667.3, score=18.8]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=126, Expect=1e-29]; ENSG00000060237, WNK1, WNK lysine deficient protein kinase 1, [Score=120, Expect=8e-27]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=120, Expect=5e-28]; ENSMUSG00000045962, Wnk1, WNK lysine deficient protein kinase 1, [Score=120, Expect=5e-27]; ENSMUSG00000041245, Wnk3, WNK lysine deficient protein kinase 3, [Score=116, Expect=3e-26]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=109, Expect=5e-24]} {Celegans: WBGene00006941, wnk-1, Serine/threonine-protein kinase WNK, [Score=106, Expect=7e-23]} {Smed: dd_Smed_v6_2030_0_14, dd_Smed_v6_2030_0_14, [Score=104, Expect=2e-23]} {RNA1509_2733, RNA1509_55677} {RNA1310_1474, RNA1509_2733, RNA1509_55677} {RNA1509_2733, RNA1509_55677, RNA815_848} |
2. | MligTC455_46559 | 1484 | 30.91 | Mlig455_056465 | Neo: - Age: logFC(26M/2M)=-0.295 |
TANC1 | 2.444 | - | - | - | 0.774 | 0.714 | 0.956 | Mlig455_056465 {REF} {Length: 2067} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=50.7]; Ankyrin repeats (3 copies) [PF12796.9, score=48.4]; Ankyrin repeat [PF13606.8, score=41.8]; Ankyrin repeats (many copies) [PF13637.8, score=41.1]; Ankyrin repeat [PF00023.32, score=36.6]} {Human: ENSG00000115183, TANC1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=57.0, Expect=5e-08]; ENSG00000145362, ANK2, ankyrin 2, [Score=57.0, Expect=5e-08]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=55.8, Expect=9e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [Score=53.1, Expect=1e-07]} {RNA1509_19702, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1310_14830, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1509_36019, RNA1509_36843, RNA1509_6963, RNA815_5101} |
3. | MligTC455_30000 | 1520 | 31.66 | Mlig455_006409 | Neo: - Age: Down-Down-Up |
NOTCH1 | 1.83 | - | - | - | 0.962 | 0.868 | - | Mlig455_006409 {REF} {Length: 2677} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=198.7]; Human growth factor-like EGF [PF12661.9, score=99.3]; EGF-like domain [PF07974.15, score=23.3]} {Human: ENSG00000148400, NOTCH1, notch 1, [Score=306, Expect=2e-87]; ENSG00000134250, NOTCH2, notch 2, [Score=305, Expect=5e-87]} {Mouse: ENSMUSG00000026923, Notch1, notch 1, [Score=312, Expect=1e-89]; ENSMUSG00000027878, Notch2, notch 2, [Score=300, Expect=9e-86]} {Dmel: FBgn0259685, crb, crumbs, [Score=291, Expect=1e-82]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=234, Expect=5e-64]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=236, Expect=9e-65]} {RNA1509_26892} {RNA1310_37026} {RNA815_11987.1} |
4. | MligTC455_10951 | 312 | 6.5 | Mlig455_035123, Mlig455_071126 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.446 Region-enriched R7: 2.734/0.00691 |
OXSR1 | 1.778 | - | - | - | 0.961 | 0.817 | - | Mlig455_035123 {REF} {Length: 1777} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=31.6]; Protein kinase domain [PF00069.27, score=24.6]} {RNA1509_27972} {RNA1310_12789} {RNA815_5890.1} Mlig455_071126 {REF} {Length: 2025} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=119.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=115.8]; Fungal protein kinase [PF17667.3, score=29.4]} {Human: ENSG00000172939, OXSR1, oxidative stress responsive 1, [Score=89.7, Expect=1e-18]; ENSG00000198648, STK39, serine/threonine kinase 39, [Score=85.9, Expect=2e-17]; ENSG00000132155, RAF1, Raf-1 proto-oncogene, serine/threonine kinase, [Score=85.9, Expect=2e-17]} {Mouse: ENSMUSG00000036737, Oxsr1, oxidative-stress responsive 1, [Score=88.6, Expect=2e-18]; ENSMUSG00000027030, Stk39, serine/threonine kinase 39, [Score=85.9, Expect=2e-17]; ENSMUSG00000002413, Braf, Braf transforming gene, [Score=84.7, Expect=7e-17]; ENSMUSG00000000441, Raf1, v-raf-leukemia viral oncogene 1, [Score=84.7, Expect=6e-17]; ENSMUSG00000037738, Nek5, NIMA (never in mitosis gene a)-related expressed kinase 5, [Score=84.7, Expect=5e-17]} {Dmel: FBgn0046689, Takl1, Tak1-like 1, [Score=99.4, Expect=2e-22]} {Celegans: WBGene00006971, zak-1, Mammalian ZAK kinase homolog, [Score=97.1, Expect=3e-21]} {Smed: dd_Smed_v6_2589_0_2, dd_Smed_v6_2589_0_2, [Score=106, Expect=5e-25]} {RNA1509_27972, RNA1509_47040} {RNA1310_12789, RNA1509_47040} {RNA1509_47040, RNA815_5890.1} |
5. | MligTC455_27273 | 1242 | 25.88 | Mlig455_036825 | Neo: - Age: - |
RHBDL2 | 1.706 | - | 0.756 | - | 0.950 | - | - | Mlig455_036825 {REF} {Length: 3039} {Pfam: Rhomboid family [PF01694.24, score=106.0]; EF-hand domain pair [PF13499.8, score=21.6]; EF hand [PF00036.34, score=19.8]} {Human: ENSG00000158315, RHBDL2, rhomboid like 2, [Score=161, Expect=1e-44]; ENSG00000141314, RHBDL3, rhomboid like 3, [Score=153, Expect=6e-41]} {Mouse: ENSMUSG00000043333, Rhbdl2, rhomboid like 2, [Score=172, Expect=6e-49]} {Dmel: FBgn0030318, rho-4, rhomboid-4, [Score=165, Expect=2e-45]} {Celegans: WBGene00004400, rom-1, Rhomboid-related protein 1, [Score=165, Expect=4e-46]} {Smed: dd_Smed_v6_13835_0_1, dd_Smed_v6_13835_0_1, [Score=305, Expect=9e-99]} {RNA1509_2577, RNA1509_28194} {RNA1310_13375, RNA1509_2577, RNA1509_28194} {RNA1509_2577, RNA1509_28194, RNA815_2003.1} |
6. | MligTC455_54178 | 434 | 9.04 | Mlig455_020796 | Neo: - Age: Down-Down-Up Region-enriched R7: 1.941/0.00397 |
1.706 | - | - | - | 0.968 | - | 0.738 | Mlig455_020796 {REF} {Length: 2879} {Smed: dd_Smed_v6_5057_0_1, dd_Smed_v6_5057_0_1, [RH, Score=91.7, Expect=4e-20]} {RNA1509_10580} {RNA1310_9366, RNA1509_10580} {RNA1509_10580, RNA815_2566} | |
7. | MligTC455_53663 | 2058 | 42.87 | Mlig455_008115 | Neo: - Age: logFC(26M/2M)=-0.253 |
1.683 | 0.729 | - | - | 0.954 | - | - | Mlig455_008115 {REF} {Length: 2006} {Smed: dd_Smed_v6_1161_1_1, dd_Smed_v6_1161_1_1, [RH, Score=69.7, Expect=2e-13]} {RNA1509_18168, RNA1509_23504, RNA1509_9630} {RNA1310_13288.1, RNA1509_18168, RNA1509_23504, RNA1509_9630} {RNA1509_18168, RNA1509_23504, RNA1509_9630, RNA815_8569} | |
8. | MligTC455_17819 | 776 | 16.16 | Mlig455_029976 | Neo: - Age: Down-Up-Down |
GUCA1B | 1.672 | - | - | - | 0.952 | - | 0.720 | Mlig455_029976 {REF} {Length: 1140} {Pfam: EF hand [PF00036.34, score=74.9]; EF-hand domain pair [PF13499.8, score=71.2]; EF hand [PF13202.8, score=63.7]; EF-hand domain [PF13405.8, score=63.2]; EF-hand domain pair [PF13833.8, score=52.6]} {Human: ENSG00000112599, GUCA1B, guanylate cyclase activator 1B, [Score=69.7, Expect=1e-14]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=52.0, Expect=8e-09]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=51.6, Expect=2e-08]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=51.6, Expect=2e-08]; ENSMUSG00000028310, Ppp3r2, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II), [Score=50.4, Expect=1e-07]; ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [Score=50.4, Expect=8e-08]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=50.4, Expect=5e-08]} {Celegans: WBGene00003565, ncs-3, Neuronal Calcium Sensor family, [Score=67.8, Expect=3e-14]} {Smed: dd_Smed_v6_14450_0_1, dd_Smed_v6_14450_0_1, [Score=52.0, Expect=1e-08]} {RNA1509_25226} {RNA1310_34058} {RNA815_15719} |
9. | MligTC455_25613 | 657 | 13.69 | Mlig455_030148 | Neo: - Age: Down-Up-Down |
CDH23 | 0.96 | - | - | - | 0.960 | - | - | Mlig455_030148 {REF} {Length: 7253} {Pfam: Cadherin domain [PF00028.19, score=375.6]; Cadherin-like [PF08266.14, score=27.1]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=282, Expect=1e-75]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=280, Expect=4e-75]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=485, Expect=2e-141]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=171, Expect=3e-42]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=344, Expect=9e-96]} {RNA1509_1684} {RNA1310_428} {RNA815_149.1} |
10. | MligTC455_35755 | 919 | 19.14 | Mlig455_068026 | Neo: - Age: logFC(26M/2M)=-0.205 Region-enriched R7: 1.992/0.01201 |
0.95 | - | - | - | - | 0.950 | - | Mlig455_068026 {REF} {Length: 7037} {RNA1509_16355} {RNA1310_6351.1, RNA1509_16355} {RNA1509_16355, RNA815_4874} |