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Results for MligTC455_49617

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49617 561 11.69 Mlig455_053826, Mlig455_068519

Neo: -

Age: -

Region-enriched R2: 2.210/0.00459

 CPNE8, CPNE9

Mlig455_053826 {REF} {Length: 3677} {Pfam: Copine [PF07002.18, score=235.6]; Pentapeptide repeats (8 copies) [PF00805.24, score=224.2]; Pentapeptide repeats (9 copies) [PF13576.8, score=203.8]; Pentapeptide repeats (9 copies) [PF13599.8, score=185.9]; C2 domain [PF00168.32, score=40.3]; vWA found in TerF C terminus [PF10138.11, score=20.7]} {Human: ENSG00000139117, CPNE8, copine 8, [Score=301, Expect=2e-90]; ENSG00000144550, CPNE9, copine family member 9, [Score=300, Expect=4e-90]; ENSG00000124772, CPNE5, copine 5, [Score=295, Expect=2e-87]; ENSG00000214078, CPNE1, copine 1, [Score=289, Expect=3e-86]} {Mouse: ENSMUSG00000052560, Cpne8, copine VIII, [Score=302, Expect=9e-91]; ENSMUSG00000030270, Cpne9, copine family member IX, [Score=300, Expect=2e-90]; ENSMUSG00000024008, Cpne5, copine V, [Score=294, Expect=2e-87]} {Celegans: WBGene00001577, gem-4, Gon-2 Extragenic Modifier, [Score=216, Expect=8e-60]} {Smed: dd_Smed_v6_13873_0_1, dd_Smed_v6_13873_0_1, [Score=392, Expect=3e-124]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_4873}

Mlig455_068519 {REF} {Length: 2381} {Pfam: Copine [PF07002.18, score=237.0]; C2 domain [PF00168.32, score=50.8]; vWA found in TerF C terminus [PF10138.11, score=22.6]} {Human: ENSG00000144550, CPNE9, copine family member 9, [Score=407, Expect=2e-135]; ENSG00000139117, CPNE8, copine 8, [Score=398, Expect=9e-132]} {Mouse: ENSMUSG00000030270, Cpne9, copine family member IX, [Score=409, Expect=2e-136]; ENSMUSG00000052560, Cpne8, copine VIII, [Score=400, Expect=2e-132]} {Celegans: WBGene00012128, nra-1, Nicotinic receptor-associated protein 1, [Score=294, Expect=3e-91]} {Smed: dd_Smed_v6_13873_0_1, dd_Smed_v6_13873_0_1, [RH, Score=566, Expect=0.0]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_4873}

Cumulative graph for MligTC455_49617

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.667 3.924 0.24562 0.89196
RegionR2 2.21 3.924 0.00012 0.00459
RegionR3 0.64 3.924 0.19162 0.72878
RegionR4 -1.939 3.924 0.00233 0.02007
RegionR5 1.118 3.924 0.00846 0.05115
RegionR6 -1.404 3.924 0.02185 0.26747
RegionR7 -0.609 3.924 0.41359 1.00000
RegionR8 1.652 3.924 0.00944 0.18285

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -5.656 3.924 0.29039 0.98918
RegenerationR2 -0.107 3.924 0.81811 0.99458
RegenerationR3 0.797 3.924 0.14124 0.56730
RegenerationR4 -0.103 3.924 0.86835 1.00000
RegenerationR5 -0.579 3.924 0.25098 0.68481
RegenerationR6 0.293 3.924 0.66990 0.90851
RegenerationBL -0.008 3.924 0.99360 1.00000
RegenerationTP -2.47 3.924 0.00722 0.14295


Genes with expression patterns similar to MligTC455_49617

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49617 561 11.69 Mlig455_053826, Mlig455_068519

Neo: -

Age: -

Region-enriched R2: 2.210/0.00459

 CPNE8, CPNE9 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_053826 {REF} {Length: 3677} {Pfam: Copine [PF07002.18, score=235.6]; Pentapeptide repeats (8 copies) [PF00805.24, score=224.2]; Pentapeptide repeats (9 copies) [PF13576.8, score=203.8]; Pentapeptide repeats (9 copies) [PF13599.8, score=185.9]; C2 domain [PF00168.32, score=40.3]; vWA found in TerF C terminus [PF10138.11, score=20.7]} {Human: ENSG00000139117, CPNE8, copine 8, [Score=301, Expect=2e-90]; ENSG00000144550, CPNE9, copine family member 9, [Score=300, Expect=4e-90]; ENSG00000124772, CPNE5, copine 5, [Score=295, Expect=2e-87]; ENSG00000214078, CPNE1, copine 1, [Score=289, Expect=3e-86]} {Mouse: ENSMUSG00000052560, Cpne8, copine VIII, [Score=302, Expect=9e-91]; ENSMUSG00000030270, Cpne9, copine family member IX, [Score=300, Expect=2e-90]; ENSMUSG00000024008, Cpne5, copine V, [Score=294, Expect=2e-87]} {Celegans: WBGene00001577, gem-4, Gon-2 Extragenic Modifier, [Score=216, Expect=8e-60]} {Smed: dd_Smed_v6_13873_0_1, dd_Smed_v6_13873_0_1, [Score=392, Expect=3e-124]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_4873}

Mlig455_068519 {REF} {Length: 2381} {Pfam: Copine [PF07002.18, score=237.0]; C2 domain [PF00168.32, score=50.8]; vWA found in TerF C terminus [PF10138.11, score=22.6]} {Human: ENSG00000144550, CPNE9, copine family member 9, [Score=407, Expect=2e-135]; ENSG00000139117, CPNE8, copine 8, [Score=398, Expect=9e-132]} {Mouse: ENSMUSG00000030270, Cpne9, copine family member IX, [Score=409, Expect=2e-136]; ENSMUSG00000052560, Cpne8, copine VIII, [Score=400, Expect=2e-132]} {Celegans: WBGene00012128, nra-1, Nicotinic receptor-associated protein 1, [Score=294, Expect=3e-91]} {Smed: dd_Smed_v6_13873_0_1, dd_Smed_v6_13873_0_1, [RH, Score=566, Expect=0.0]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_4873}
2. MligTC455_19842 93 1.95 Mlig455_039673

Neo: -

Age: Up-Down-Up

 GRIK2 2.704 0.875 - - 0.871 0.958 - Mlig455_039673 {REF} {Length: 3561} {Pfam: Ligand-gated ion channel [PF00060.28, score=141.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=63.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=61.6]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=327, Expect=7e-97]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=322, Expect=1e-94]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=327, Expect=8e-97]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=322, Expect=1e-94]} {Dmel: FBgn0038837, CG3822, [Score=320, Expect=1e-94]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=299, Expect=2e-86]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=392, Expect=3e-120]} {RNA1509_45189} {RNA1310_13827.1} {RNA815_34006}
3. MligTC455_52726 213 4.44 Mlig455_032119

Neo: -

Age: -

Region-enriched R2: 4.573/0.00005

 2.643 - - 0.799 0.888 0.956 - Mlig455_032119 {REF} {Length: 2626} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=61.9]; Capsular polysaccharide synthesis protein [PF05704.14, score=21.0]} {Smed: dd_Smed_v6_6819_0_1, dd_Smed_v6_6819_0_1, [Score=137, Expect=2e-37]} {RNA1509_41314} {RNA1310_26265} {RNA815_9794.1}
4. MligTC455_15996 396 8.26 Mlig455_064976, Mlig455_066809

Neo: -

Age: -

 ARHGEF17 2.601 - 0.728 - 0.915 0.958 -

Mlig455_064976 {REF} {Length: 4968} {Pfam: WD40 repeated domain [PF19056.2, score=146.7]; RhoGEF domain [PF00621.22, score=136.4]} {Human: ENSG00000110237, ARHGEF17, Rho guanine nucleotide exchange factor 17, [Score=233, Expect=6e-61]} {Mouse: ENSMUSG00000032875, Arhgef17, Rho guanine nucleotide exchange factor (GEF) 17, [Score=239, Expect=3e-63]} {Dmel: FBgn0262562, CG43102, [RH, Score=520, Expect=4e-156]} {Celegans: WBGene00019832, osg-1, Rho guanine nucleotide exchange factor osg-1, [RH, Score=240, Expect=2e-64]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [RH, Score=713, Expect=0.0]} {RNA1509_36394} {RNA1310_6117.1} {RNA815_14497}

Mlig455_066809 {REF} {Length: 5061} {Pfam: WD40 repeated domain [PF19056.2, score=146.7]; RhoGEF domain [PF00621.22, score=125.9]} {Human: ENSG00000110237, ARHGEF17, Rho guanine nucleotide exchange factor 17, [RH, Score=266, Expect=2e-71]} {Mouse: ENSMUSG00000032875, Arhgef17, Rho guanine nucleotide exchange factor (GEF) 17, [RH, Score=264, Expect=1e-70]} {Dmel: FBgn0262562, CG43102, [RH, Score=503, Expect=8e-150]} {Celegans: WBGene00019832, osg-1, Rho guanine nucleotide exchange factor osg-1, [Score=224, Expect=3e-59]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [RH, Score=691, Expect=0.0]} {RNA1509_36394} {RNA1310_6117.1} {RNA815_23184}
5. MligTC455_34693 336 7 Mlig455_017459

Neo: -

Age: -

Region-enriched R2: 6.024/0.00000
Region-enriched R3: 3.452/0.00414

 FZD4 1.884 - - - 0.916 0.968 - Mlig455_017459 {REF} {Length: 3882} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=335.8]; Fz domain [PF01392.24, score=90.0]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=424, Expect=3e-141]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=423, Expect=3e-141]} {Dmel: FBgn0001085, fz, frizzled, [Score=306, Expect=2e-95]} {Celegans: WBGene00003006, lin-17, Transmembrane receptor LIN-17, [RH, Score=271, Expect=1e-82]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=473, Expect=3e-160]} {RNA1509_10294} {RNA1310_2672} {RNA815_3209}
6. MligTC455_46285 568 11.84 Mlig455_063390

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R2: 4.933/0.00026
Region-enriched R3: 3.321/0.00307

 1.883 - - - 0.913 0.970 - Mlig455_063390 {REF} {Length: 871} {RNA1509_48573} {RNA1310_59611, RNA1509_48573} {RNA1509_48573, RNA815_35731}
7. MligTC455_43676 56 1.16 Mlig455_058053, Mlig455_058096

Neo: -

Age: -

 1.882 - - - 0.918 0.964 -

Mlig455_058053 {REF} {Length: 391} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_102705} {RNA815_52459}

Mlig455_058096 {REF} {Length: 1983} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=51.3]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=90.1, Expect=1e-19]} {RNA1509_1472} {RNA1310_25467} {RNA815_39314}
8. MligTC455_53813 46 0.96 Mlig455_038036

Neo: -

Age: Down-Down-Up

 1.859 - 0.892 - - 0.967 - Mlig455_038036 {REF} {Length: 1511} {Smed: dd_Smed_v6_12148_0_3, dd_Smed_v6_12148_0_3, [Score=70.5, Expect=9e-14]} {RNA1310_21968} {RNA815_20437}
9. MligTC455_17947 64 1.34 Mlig455_042563

Neo: -

Age: -

Region-enriched R2: 7.054/0.00113

 ASCL5 1.856 - - - 0.877 0.979 - Mlig455_042563 {REF} {Length: 1821} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=52.5]} {Human: ENSG00000232237, ASCL5, achaete-scute family bHLH transcription factor 5, [Score=84.7, Expect=6e-20]} {Mouse: ENSMUSG00000097918, Ascl5, achaete-scute family bHLH transcription factor 5, [Score=84.0, Expect=5e-20]} {Dmel: FBgn0002922, nau, nautilus, [Score=49.3, Expect=6e-07]} {Celegans: WBGene00001952, hlh-6, Helix-loop-helix protein 6, [RH, Score=90.9, Expect=4e-22]} {Smed: dd_Smed_v6_14753_0_1, dd_Smed_v6_14753_0_1, [RH, Score=76.6, Expect=2e-17]} {RNA1310_71187}
10. MligTC455_47741 102 2.13 Mlig455_004211

Neo: -

Age: Down-Up-Up

 1.846 - - - 0.883 0.963 - Mlig455_004211 {REF} {Length: 1794} {RNA1310_23101} {RNA815_45601}
11. MligTC455_52003 1043 21.73 Mlig455_050564, Mlig455_050571

Neo: -

Age: -

 RGS4, RGS8 1.844 - - - 0.890 0.954 -

Mlig455_050564 {REF} {Length: 3240} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=116.7]} {Human: ENSG00000117152, RGS4, regulator of G protein signaling 4, [RH, Score=149, Expect=2e-42]} {Mouse: ENSMUSG00000038530, Rgs4, regulator of G-protein signaling 4, [RH, Score=153, Expect=4e-44]; ENSMUSG00000026678, Rgs5, regulator of G-protein signaling 5, [RH, Score=149, Expect=1e-42]; ENSMUSG00000042671, Rgs8, regulator of G-protein signaling 8, [RH, Score=149, Expect=1e-42]} {Dmel: FBgn0028743, Dhit, Double hit, [Score=118, Expect=2e-30]} {Celegans: WBGene00004350, rgs-7, Regulator of G-protein signaling rgs-7, [Score=124, Expect=4e-33]} {Smed: dd_Smed_v6_8648_0_1, dd_Smed_v6_8648_0_1, [RH, Score=199, Expect=4e-58]} {RNA1509_11015, RNA1509_27306} {RNA1310_4876, RNA1509_11015, RNA1509_27306} {RNA1509_11015, RNA1509_27306, RNA815_6054}

Mlig455_050571 {REF} {Length: 2222} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=118.3]} {Human: ENSG00000135824, RGS8, regulator of G protein signaling 8, [RH, Score=149, Expect=9e-45]; ENSG00000117152, RGS4, regulator of G protein signaling 4, [RH, Score=149, Expect=2e-44]; ENSG00000150681, RGS18, regulator of G protein signaling 18, [RH, Score=146, Expect=5e-43]; ENSG00000143248, RGS5, regulator of G protein signaling 5, [RH, Score=144, Expect=7e-43]} {Mouse: ENSMUSG00000038530, Rgs4, regulator of G-protein signaling 4, [RH, Score=153, Expect=5e-46]; ENSMUSG00000042671, Rgs8, regulator of G-protein signaling 8, [RH, Score=151, Expect=1e-45]; ENSMUSG00000026678, Rgs5, regulator of G-protein signaling 5, [RH, Score=147, Expect=7e-44]} {Dmel: FBgn0028743, Dhit, Double hit, [Score=117, Expect=1e-31]} {Celegans: WBGene00004350, rgs-7, Regulator of G-protein signaling rgs-7, [Score=124, Expect=7e-35]} {Smed: dd_Smed_v6_8648_0_1, dd_Smed_v6_8648_0_1, [RH, Score=192, Expect=1e-57]} {RNA1509_27306} {RNA1310_5436.1} {RNA815_6054}
12. MligTC455_18161 771 16.05 Mlig455_031626, Mlig455_048205

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.318/0.00160

 1.843 - - - 0.881 0.962 -

Mlig455_031626 {REF} {Length: 835} {TRANSSPLICED} {RNA1509_48514} {RNA1310_56583, RNA1509_48514} {RNA1509_48514, RNA815_34758}

Mlig455_048205 {REF} {Length: 651} {RNA1509_48514} {RNA1310_56583} {RNA815_34758}
13. MligTC455_46581 31 0.64 Mlig455_042524

Neo: -

Age: -

 1.842 - - - 0.881 0.961 - Mlig455_042524 {REF} {Length: 975} {RNA1509_46101} {RNA1310_32444} {RNA815_42659}
14. MligTC455_19578 23 0.47 Mlig455_018093, Mlig455_059526

Neo: -

Age: -

 1.841 - - - 0.888 0.953 -

Mlig455_018093 {REF} {Length: 2450} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=99.2]} {Smed: dd_Smed_v6_21491_0_1, dd_Smed_v6_21491_0_1, [Score=72.4, Expect=4e-13]} {RNA1310_65251}

Mlig455_059526 {REF} {Length: 2621} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.4]} {Smed: dd_Smed_v6_21491_0_1, dd_Smed_v6_21491_0_1, [Score=74.7, Expect=8e-14]} {RNA1310_65251}
15. MligTC455_12484 808 16.84 Mlig455_054887

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.064/0.02321

 LTBP2 1.84 - - - 0.974 0.866 - Mlig455_054887 {REF} {Length: 5896} {Pfam: Calcium-binding EGF domain [PF07645.17, score=86.1]; Complement Clr-like EGF-like [PF12662.9, score=59.0]; EGF-like domain [PF00008.29, score=26.1]; Human growth factor-like EGF [PF12661.9, score=20.0]; Coagulation Factor Xa inhibitory site [PF14670.8, score=19.9]} {Human: ENSG00000119681, LTBP2, latent transforming growth factor beta binding protein 2, [Score=149, Expect=2e-35]; ENSG00000049323, LTBP1, latent transforming growth factor beta binding protein 1, [Score=142, Expect=3e-33]} {Mouse: ENSMUSG00000002020, Ltbp2, latent transforming growth factor beta binding protein 2, [Score=141, Expect=5e-33]; ENSMUSG00000024598, Fbn2, fibrillin 2, [Score=141, Expect=5e-33]; ENSMUSG00000040488, Ltbp4, latent transforming growth factor beta binding protein 4, [Score=137, Expect=6e-32]; ENSMUSG00000027204, Fbn1, fibrillin 1, [Score=136, Expect=1e-31]} {Dmel: FBgn0035798, frac, faulty attraction, [Score=122, Expect=2e-27]} {Celegans: WBGene00022816, fbn-1, FBN-1A.1; FiBrilliN homolog, [Score=108, Expect=4e-23]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=121, Expect=3e-27]} {RNA1509_52818} {RNA1310_702.1, RNA1509_52818} {RNA1509_52818, RNA815_201.1}
16. MligTC455_40011 150 3.12 Mlig455_004436, Mlig455_004448

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.676

 1.835 - - - 0.871 0.964 -

Mlig455_004436 {REF} {Length: 595} {RNA1310_81676}

Mlig455_004448 {REF} {Length: 1192} {RNA1310_81676}
17. MligTC455_10024 48 0.99 Mlig455_065062

Neo: -

Age: -

 1.831 - - - 0.870 0.961 - Mlig455_065062 {REF} {Length: 3160} {RNA1310_7348} {RNA815_14995}
18. MligTC455_28055 19 0.41 Mlig455_048300, Mlig455_048327, Mlig455_048344

Neo: -

Age: -

 MARK2, MARK4 1.816 - - - 0.848 0.968 -

Mlig455_048300 {REF} {Length: 2504} {Pfam: Protein kinase domain [PF00069.27, score=157.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=86.8]; Kinase-like [PF14531.8, score=21.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.4]} {Human: ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=158, Expect=1e-39]; ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [Score=157, Expect=2e-39]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=152, Expect=7e-38]; ENSG00000160584, SIK3, SIK family kinase 3, [Score=152, Expect=2e-37]; ENSG00000074590, NUAK1, NUAK family kinase 1, [Score=151, Expect=1e-37]} {Mouse: ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=158, Expect=8e-40]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=156, Expect=3e-39]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [Score=152, Expect=8e-38]; ENSMUSG00000009772, Nuak2, NUAK family, SNF1-like kinase, 2, [Score=151, Expect=7e-38]; ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=151, Expect=4e-37]; ENSMUSG00000020032, Nuak1, NUAK family, SNF1-like kinase, 1, [Score=151, Expect=1e-37]} {Dmel: FBgn0026064, KP78a, [Score=156, Expect=2e-39]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=163, Expect=4e-41]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [Score=317, Expect=1e-97]} {RNA1310_58898} {RNA815_35373}

Mlig455_048327 {REF} {Length: 2998} {Pfam: Protein kinase domain [PF00069.27, score=157.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=86.7]; Kinase-like [PF14531.8, score=21.4]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.3]} {Human: ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [Score=159, Expect=1e-39]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=159, Expect=6e-40]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=153, Expect=5e-38]; ENSG00000160584, SIK3, SIK family kinase 3, [Score=153, Expect=2e-37]; ENSG00000074590, NUAK1, NUAK family kinase 1, [Score=152, Expect=1e-37]} {Mouse: ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=159, Expect=7e-40]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=157, Expect=2e-39]; ENSMUSG00000009772, Nuak2, NUAK family, SNF1-like kinase, 2, [Score=152, Expect=5e-38]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [Score=152, Expect=5e-38]; ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=152, Expect=3e-37]} {Dmel: FBgn0026064, KP78a, [Score=157, Expect=9e-40]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=164, Expect=2e-41]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [Score=318, Expect=1e-97]} {RNA1310_58898} {RNA815_35373}

Mlig455_048344 {REF} {Length: 2992} {Pfam: Protein kinase domain [PF00069.27, score=216.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=130.0]; Kinase-like [PF14531.8, score=22.0]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.6]} {Human: ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=213, Expect=1e-58]; ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [Score=212, Expect=6e-58]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [Score=207, Expect=3e-56]; ENSG00000160584, SIK3, SIK family kinase 3, [Score=206, Expect=2e-54]} {Mouse: ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [Score=212, Expect=3e-58]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=212, Expect=5e-58]; ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=207, Expect=3e-55]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [Score=206, Expect=4e-56]} {Dmel: FBgn0026064, KP78a, [Score=213, Expect=1e-58]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=217, Expect=7e-59]} {Smed: dd_Smed_v6_14823_0_1, dd_Smed_v6_14823_0_1, [RH, Score=465, Expect=5e-154]} {RNA1310_58898} {RNA815_35373}
19. MligTC455_17039 24 0.5 Mlig455_025016

Neo: -

Age: -

 1.811 - - - 0.839 0.972 - Mlig455_025016 {REF} {Length: 2009} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=72.7]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.5]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=18.8]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [RH, Score=209, Expect=1e-63]} {RNA1310_42205} {RNA815_15017}
20. MligTC455_48757 61 1.28 Mlig455_008828, Mlig455_008932

Neo: -

Age: Up-Down-Up

 DDC 1.809 - - - 0.838 0.971 -

Mlig455_008828 {REF} {Length: 2057} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=471.9]} {Human: ENSG00000132437, DDC, dopa decarboxylase, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000020182, Ddc, dopa decarboxylase, [RH, Score=558, Expect=0.0]} {Dmel: FBgn0000422, Ddc, Dopa decarboxylase, [RH, Score=553, Expect=0.0]} {Celegans: WBGene00006562, tdc-1, Tyrosine decarboxylase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_11320_0_1, dd_Smed_v6_11320_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_37174} {RNA815_42090}

Mlig455_008932 {REF} {Length: 2145} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=470.1]} {Human: ENSG00000132437, DDC, dopa decarboxylase, [RH, Score=574, Expect=0.0]} {Mouse: ENSMUSG00000020182, Ddc, dopa decarboxylase, [RH, Score=559, Expect=0.0]} {Dmel: FBgn0000422, Ddc, Dopa decarboxylase, [RH, Score=554, Expect=0.0]} {Celegans: WBGene00006562, tdc-1, Tyrosine decarboxylase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_11320_0_1, dd_Smed_v6_11320_0_1, [RH, Score=564, Expect=0.0]} {RNA1310_37174} {RNA815_42090}
21. MligTC455_12105 21 0.43 Mlig455_015631

Neo: -

Age: -

 1.806 - - - 0.849 0.957 - Mlig455_015631 {REF} {Length: 1685} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=64.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.3]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=22.5]} {Smed: dd_Smed_v6_13742_0_1, dd_Smed_v6_13742_0_1, [Score=82.4, Expect=2e-17]} {RNA1310_95837}
22. MligTC455_46502 168 3.5 Mlig455_010557

Neo: -

Age: -

 1.798 - - - 0.839 0.959 - Mlig455_010557 {REF} {Length: 557} {Pfam: HalX domain [PF08663.12, score=24.3]} {RNA1509_57107} {RNA1310_80026, RNA1509_57107} {RNA1509_57107, RNA815_41799}
23. MligTC455_48760 15 0.31 Mlig455_009006

Neo: -

Age: -

 SULT1A1 1.793 - - - 0.830 0.963 - Mlig455_009006 {REF} {Length: 1306} {Pfam: Sulfotransferase domain [PF00685.29, score=204.1]; Sulfotransferase family [PF13469.8, score=33.6]} {Human: ENSG00000196502, SULT1A1, sulfotransferase family 1A member 1, [RH, Score=162, Expect=4e-47]} {Mouse: ENSMUSG00000029269, Sult1b1, sulfotransferase family 1B, member 1, [RH, Score=167, Expect=8e-49]} {Dmel: FBgn0037665, St2, Sulfotransferase 2, [Score=131, Expect=4e-35]} {Celegans: WBGene00013748, ssu-1, Suppressor of Stomatin mutant Uncoordination, [Score=108, Expect=2e-26]} {Smed: dd_Smed_v6_34919_0_1, dd_Smed_v6_34919_0_1, [RH, Score=276, Expect=2e-91]} {RNA1310_95833}
24. MligTC455_45880 278 5.8 Mlig455_051498

Neo: -

Age: -

Region-enriched R2: 5.081/0.00218

 CALM2 1.789 - - - 0.818 0.971 - Mlig455_051498 {REF} {Length: 2328} {Pfam: EF-hand domain pair [PF13499.8, score=48.0]; EF-hand domain [PF14658.8, score=32.2]; EF-hand domain [PF13405.8, score=23.0]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=84.0, Expect=1e-20]; ENSG00000160014, CALM3, calmodulin 3, [Score=84.0, Expect=1e-20]; ENSG00000198668, CALM1, calmodulin 1, [Score=84.0, Expect=1e-20]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=84.0, Expect=9e-21]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=84.0, Expect=9e-21]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=84.0, Expect=9e-21]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=82.8, Expect=2e-20]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=82.8, Expect=1e-20]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=82.8, Expect=9e-21]} {RNA1509_41430} {RNA1310_44424} {RNA815_28870}
25. MligTC455_13504 29 0.6 Mlig455_027732

Neo: -

Age: Up-Up-Down

 KCND2 1.787 - - - - 0.974 0.813 Mlig455_027732 {REF} {Length: 5011} {Pfam: Ion transport protein [PF00520.33, score=127.7]; BTB/POZ domain [PF02214.24, score=91.1]; Ion channel [PF07885.18, score=49.3]; Shal-type voltage-gated potassium channels, N-terminal [PF11601.10, score=48.9]; Domain of unknown function (DUF3399) [PF11879.10, score=42.8]; BTB/POZ domain [PF16017.7, score=28.0]} {Human: ENSG00000184408, KCND2, potassium voltage-gated channel subfamily D member 2, [RH, Score=719, Expect=0.0]; ENSG00000171385, KCND3, potassium voltage-gated channel subfamily D member 3, [RH, Score=711, Expect=0.0]; ENSG00000102057, KCND1, potassium voltage-gated channel subfamily D member 1, [RH, Score=691, Expect=0.0]} {Mouse: ENSMUSG00000060882, Kcnd2, potassium voltage-gated channel, Shal-related family, member 2, [RH, Score=716, Expect=0.0]; ENSMUSG00000040896, Kcnd3, potassium voltage-gated channel, Shal-related family, member 3, [RH, Score=712, Expect=0.0]; ENSMUSG00000009731, Kcnd1, potassium voltage-gated channel, Shal-related family, member 1, [RH, Score=695, Expect=0.0]} {Dmel: FBgn0005564, Shal, Shaker cognate l, [RH, Score=748, Expect=0.0]} {Celegans: WBGene00022240, shl-1, SHaL family of potassium channels, [RH, Score=712, Expect=0.0]} {Smed: dd_Smed_v6_15876_0_1, dd_Smed_v6_15876_0_1, [RH, Score=713, Expect=0.0]} {RNA1509_23965, RNA1509_36535, RNA1509_40621, RNA1509_53481, RNA1509_55146} {RNA1310_7319, RNA1509_23965, RNA1509_36535, RNA1509_40621, RNA1509_53481, RNA1509_55146} {RNA1509_23965, RNA1509_36535, RNA1509_40621, RNA1509_53481, RNA1509_55146, RNA815_9248}
26. MligTC455_02622 18 0.38 Mlig455_034646, Mlig455_062629

Neo: -

Age: -

 CACNG5 1.782 - - - 0.808 0.974 -

Mlig455_034646 {REF} {Length: 1447} {Pfam: PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=49.4]; PMP-22/EMP/MP20/Claudin family [PF00822.22, score=36.5]} {Human: ENSG00000075429, CACNG5, calcium voltage-gated channel auxiliary subunit gamma 5, [Score=73.2, Expect=3e-14]} {Mouse: ENSMUSG00000040373, Cacng5, calcium channel, voltage-dependent, gamma subunit 5, [Score=72.4, Expect=4e-14]} {RNA1310_115007} {RNA815_41269}

Mlig455_062629 {REF} {Length: 1628} {Pfam: PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=49.4]; PMP-22/EMP/MP20/Claudin family [PF00822.22, score=36.5]} {Human: ENSG00000075429, CACNG5, calcium voltage-gated channel auxiliary subunit gamma 5, [Score=73.2, Expect=3e-14]} {Mouse: ENSMUSG00000040373, Cacng5, calcium channel, voltage-dependent, gamma subunit 5, [Score=72.4, Expect=4e-14]} {RNA1310_115007} {RNA815_41269}
27. MligTC455_45881 285 5.94 Mlig455_051535

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R2: 4.287/0.00883

 CALM2 1.779 - - - 0.813 0.966 - Mlig455_051535 {REF} {Length: 1911} {Pfam: EF-hand domain pair [PF13499.8, score=44.7]; EF-hand domain [PF14658.8, score=28.5]; EF-hand domain [PF13405.8, score=18.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=83.2, Expect=5e-18]; ENSG00000198668, CALM1, calmodulin 1, [Score=83.2, Expect=1e-18]; ENSG00000160014, CALM3, calmodulin 3, [Score=82.8, Expect=2e-18]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=82.8, Expect=1e-18]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=82.8, Expect=1e-18]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=82.8, Expect=1e-18]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=82.4, Expect=2e-18]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=82.4, Expect=1e-18]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=82.4, Expect=1e-18]} {RNA1509_41430} {RNA1310_57772} {RNA815_28870}
28. MligTC455_43038 44 0.92 Mlig455_015669

Neo: -

Age: -

 1.764 - - - 0.952 0.812 - Mlig455_015669 {REF} {Length: 1488} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=94.0, Expect=2e-22]} {RNA1310_25409} {RNA815_23260}
29. MligTC455_46022 51 1.07 Mlig455_009838

Neo: -

Age: -

 1.722 - - - 0.759 0.963 - Mlig455_009838 {REF} {Length: 1632} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=54.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.2]} {Dmel: FBgn0038874, ETHR, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_17171_0_1, dd_Smed_v6_17171_0_1, [Score=175, Expect=2e-51]} {RNA1310_62858} {RNA815_33606}
30. MligTC455_31463 20 0.42 Mlig455_057169

Neo: -

Age: -

 1.72 - - - 0.746 0.974 - Mlig455_057169 {REF} {Length: 1647} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=39.0]} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=82.4, Expect=3e-18]} {RNA1509_6604} {RNA1310_43619} {RNA815_6128.2}
31. MligTC455_19449 235 4.9 Mlig455_048896

Neo: -

Age: logFC(26M/2M)=-0.470

Region-enriched R2: 3.185/0.00006

 1.719 - - - 0.767 0.952 - Mlig455_048896 {REF} {Length: 1819} {Pfam: Innexin [PF00876.20, score=25.6]} {RNA1509_47060} {RNA1310_19756.1, RNA1509_47060} {RNA1509_47060, RNA815_16217}
32. MligTC455_17187 85 1.77 Mlig455_040722

Neo: -

Age: logFC(26M/2M)=-0.644

 SCNN1B 1.706 - - - 0.754 0.952 - Mlig455_040722 {REF} {Length: 2368} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=164.4]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=64.3, Expect=5e-10]} {Mouse: ENSMUSG00000020704, Asic2, acid-sensing (proton-gated) ion channel 2, [Score=58.5, Expect=2e-08]} {Smed: dd_Smed_v6_25838_0_1, dd_Smed_v6_25838_0_1, [Score=230, Expect=3e-67]} {RNA1509_57515} {RNA1310_24808, RNA1509_57515} {RNA1509_57515, RNA815_46525}
33. MligTC455_31462 23 0.48 Mlig455_000844

Neo: -

Age: -

 1.705 - - - 0.731 0.974 - Mlig455_000844 {REF} {Length: 2564} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=39.1]} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=81.6, Expect=5e-18]} {RNA1509_6604} {RNA1310_43619} {RNA815_6128.2}
34. MligTC455_51260 90 1.88 Mlig455_009349

Neo: -

Age: -

 1.701 - - - 0.731 0.970 - Mlig455_009349 {REF} {Length: 1657} {Pfam: Universal stress protein family [PF00582.28, score=83.5]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=97.8, Expect=2e-24]} {RNA1310_30400} {RNA815_28361}
35. MligTC455_48324 1746 36.38 Mlig455_058196

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.604

Region-enriched R3: 5.386/0.00000

 ZAN 1.695 - - - 0.734 0.961 - Mlig455_058196 {REF} {Length: 2399} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=150, Expect=3e-37]} {Mouse: ENSMUSG00000049008, BB014433, expressed sequence BB014433, [Score=67.0, Expect=2e-11]; ENSMUSG00000079173, Zan, zonadhesin, [Score=63.9, Expect=5e-10]} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=109, Expect=6e-25]} {RNA1509_27445} {RNA1310_7841} {RNA815_14882.1}
36. MligTC455_36074 372 7.74 Mlig455_010283

Neo: -

Age: -

Region-enriched R3: 1.594/0.02686

 ACE 1.693 - - - 0.954 0.739 - Mlig455_010283 {REF} {Length: 2915} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=556.6]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=410, Expect=6e-134]; ENSG00000264813, AC113554.1, novel transcript, [Score=410, Expect=9e-134]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=428, Expect=6e-141]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=360, Expect=3e-116]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=154, Expect=6e-39]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [RH, Score=441, Expect=1e-147]} {RNA1509_25217, RNA1509_36855} {RNA1310_6815, RNA1509_25217, RNA1509_36855} {RNA1509_25217, RNA1509_36855, RNA815_11444}
37. MligTC455_38699 267 5.56 Mlig455_054929

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.183/0.01222

 COLEC10 1.693 - - - 0.733 0.960 - Mlig455_054929 {REF} {Length: 1403} {Pfam: Lectin C-type domain [PF00059.23, score=45.4]} {Human: ENSG00000184374, COLEC10, collectin subfamily member 10, [Score=50.4, Expect=2e-07]} {Mouse: ENSMUSG00000038591, Colec10, collectin sub-family member 10, [Score=47.8, Expect=1e-06]} {RNA1509_22697} {RNA1310_23822} {RNA815_11460}
38. MligTC455_34819 168 3.5 Mlig455_010505, Mlig455_061873

Neo: -

Age: Up-Down-Down

 QRFPR 1.69 - - - 0.720 0.970 -

Mlig455_010505 {REF} {Length: 4092} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=158.0]; Olfactory receptor [PF13853.8, score=19.8]} {Human: ENSG00000186867, QRFPR, pyroglutamylated RFamide peptide receptor, [RH, Score=166, Expect=1e-45]} {Mouse: ENSMUSG00000029917, C130060K24Rik, RIKEN cDNA C130060K24 gene, [RH, Score=150, Expect=3e-40]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=137, Expect=2e-34]} {Celegans: WBGene00007635, npr-4, NeuroPeptide Receptor family, [Score=122, Expect=4e-30]} {Smed: dd_Smed_v6_22952_0_1, dd_Smed_v6_22952_0_1, [Score=194, Expect=4e-57]} {RNA1310_26846} {RNA815_28382}

Mlig455_061873 {REF} {Length: 3092} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=131.2]; Olfactory receptor [PF13853.8, score=19.8]} {Human: ENSG00000186867, QRFPR, pyroglutamylated RFamide peptide receptor, [Score=131, Expect=4e-33]} {Mouse: ENSMUSG00000035528, Npffr2, neuropeptide FF receptor 2, [Score=115, Expect=1e-27]; ENSMUSG00000028004, Npy2r, neuropeptide Y receptor Y2, [Score=112, Expect=4e-27]; ENSMUSG00000020090, Npffr1, neuropeptide FF receptor 1, [Score=112, Expect=1e-26]} {Dmel: FBgn0038880, SIFaR, SIFamide receptor, [Score=112, Expect=5e-26]} {Celegans: WBGene00016110, npr-11, Putative neuropeptide Y receptor 11, [Score=103, Expect=5e-24]} {Smed: dd_Smed_v6_22952_0_1, dd_Smed_v6_22952_0_1, [Score=162, Expect=4e-45]} {RNA1310_26846} {RNA815_28382}
39. MligTC455_22502 209 4.36 Mlig455_003008, Mlig455_054590

Neo: -

Age: Up-Down-Down

 SLC6A4 1.681 - - - 0.703 0.978 -

Mlig455_003008 {REF} {Length: 3661} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=681.8]} {Human: ENSG00000108576, SLC6A4, solute carrier family 6 member 4, [RH, Score=610, Expect=0.0]} {Mouse: ENSMUSG00000020838, Slc6a4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, [RH, Score=599, Expect=0.0]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [RH, Score=631, Expect=0.0]} {Celegans: WBGene00003387, mod-5, Transporter, [RH, Score=559, Expect=0.0]} {Smed: dd_Smed_v6_12700_0_1, dd_Smed_v6_12700_0_1, [RH, Score=691, Expect=0.0]} {RNA1509_33614} {RNA1310_10815} {RNA815_8003}

Mlig455_054590 {REF} {Length: 3660} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=387.2]} {Human: ENSG00000108576, SLC6A4, solute carrier family 6 member 4, [Score=345, Expect=6e-114]} {Mouse: ENSMUSG00000020838, Slc6a4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, [Score=339, Expect=9e-112]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [Score=336, Expect=6e-111]} {Celegans: WBGene00003387, mod-5, Transporter, [Score=332, Expect=7e-109]} {Smed: dd_Smed_v6_12700_0_1, dd_Smed_v6_12700_0_1, [Score=357, Expect=2e-118]} {RNA1509_33614} {RNA1310_10815} {RNA815_8003}
40. MligTC455_50734 175 3.66 Mlig455_044294

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.054/0.00263
Region-enriched R3: 3.364/0.00377

 CHRNA3 1.676 - - - 0.973 0.703 - Mlig455_044294 {REF} {Length: 1830} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=242.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=225.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=373, Expect=1e-123]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=365, Expect=1e-120]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=360, Expect=9e-119]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=358, Expect=6e-118]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=376, Expect=3e-125]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=374, Expect=4e-124]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=450, Expect=4e-154]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=381, Expect=2e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [RH, Score=651, Expect=0.0]} {RNA1509_45903} {RNA1310_14580} {RNA815_10044.1}
41. MligTC455_22501 73 1.51 Mlig455_036417

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.645

 SLC6A4 1.674 - - - 0.704 0.970 - Mlig455_036417 {REF} {Length: 3681} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=681.8]} {Human: ENSG00000108576, SLC6A4, solute carrier family 6 member 4, [RH, Score=610, Expect=0.0]} {Mouse: ENSMUSG00000020838, Slc6a4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, [RH, Score=599, Expect=0.0]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [RH, Score=631, Expect=0.0]} {Celegans: WBGene00003387, mod-5, Transporter, [RH, Score=559, Expect=0.0]} {Smed: dd_Smed_v6_12700_0_1, dd_Smed_v6_12700_0_1, [RH, Score=691, Expect=0.0]} {RNA1509_33614} {RNA1310_10815, RNA1509_33614} {RNA1509_33614, RNA815_8003}
42. MligTC455_13734 19 0.4 Mlig455_066088

Neo: -

Age: Down-Up-Down

 1.662 - - - 0.704 0.958 - Mlig455_066088 {REF} {Length: 1207} {RNA1310_47485} {RNA815_44269}
43. MligTC455_23785 36 0.75 Mlig455_001521

Neo: -

Age: Up-Down-Down

 BRSK1 1.662 - - - 0.954 0.708 - Mlig455_001521 {REF} {Length: 3554} {Pfam: Protein kinase domain [PF00069.27, score=239.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=129.4]; Phosphotransferase enzyme family [PF01636.25, score=24.0]} {Human: ENSG00000160469, BRSK1, BR serine/threonine kinase 1, [RH, Score=665, Expect=0.0]} {Mouse: ENSMUSG00000035390, Brsk1, BR serine/threonine kinase 1, [RH, Score=665, Expect=0.0]} {Dmel: FBgn0036544, sff, sugar-free frosting, [RH, Score=605, Expect=0.0]} {Celegans: WBGene00004719, sad-1, Serine/threonine kinase SAD-1, [RH, Score=600, Expect=0.0]} {Smed: dd_Smed_v6_5328_1_3, dd_Smed_v6_5328_1_3, [RH, Score=694, Expect=0.0]} {RNA1509_20961} {RNA1310_11093.1} {RNA815_12027}
44. MligTC455_37026 109 2.28 Mlig455_029463

Neo: -

Age: -

 1.654 - - - 0.704 0.950 - Mlig455_029463 {REF} {Length: 788} {RNA1310_43520} {RNA815_2407}
45. MligTC455_13074 12 0.24 Mlig455_061874

Neo: -

Age: -

 STOM 0.979 - - - - 0.979 - Mlig455_061874 {REF} {Length: 1208} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=99.9]} {Human: ENSG00000148175, STOM, stomatin, [Score=261, Expect=9e-86]; ENSG00000133115, STOML3, stomatin like 3, [Score=251, Expect=5e-82]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=256, Expect=4e-84]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=244, Expect=3e-79]} {Dmel: FBgn0260657, CG42540, [Score=261, Expect=7e-85]} {Celegans: WBGene00006063, sto-1, Stomatin-1, [Score=261, Expect=9e-86]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=292, Expect=2e-98]} {RNA1310_123385}
46. MligTC455_02873 6 0.12 Mlig455_022443

Neo: -

Age: -

 0.977 - - - - 0.977 - Mlig455_022443 {REF} {Length: 974} {Pfam: WSC domain [PF01822.21, score=48.4]; PAN domain [PF00024.28, score=24.1]} {RNA1509_29094} {RNA1310_59466.1} {RNA815_19988}
47. MligTC455_07208 41 0.86 Mlig455_013021

Neo: -

Age: -

 0.977 - - - - 0.977 - Mlig455_013021 {REF} {Length: 876} {Pfam: Lectin C-type domain [PF00059.23, score=28.4]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.1, Expect=6e-11]} {RNA1509_20946} {RNA1310_57972} {RNA815_4785.4}
48. MligTC455_09603 17 0.36 Mlig455_029150

Neo: -

Age: Down-Up-Down

 STAC 0.976 - - - - 0.976 - Mlig455_029150 {REF} {Length: 4216} {Pfam: SH3 domain [PF00018.30, score=41.4]; Variant SH3 domain [PF14604.8, score=35.9]} {Human: ENSG00000144681, STAC, SH3 and cysteine rich domain, [RH, Score=68.9, Expect=1e-11]; ENSG00000141750, STAC2, SH3 and cysteine rich domain 2, [RH, Score=67.0, Expect=5e-11]} {Mouse: ENSMUSG00000032502, Stac, src homology three (SH3) and cysteine rich domain, [RH, Score=68.9, Expect=9e-12]} {Dmel: FBgn0263980, CG43729, [RH, Score=100, Expect=1e-21]} {Celegans: WBGene00006791, unc-57, Endophilin-A homolog, [Score=53.9, Expect=1e-08]} {Smed: dd_Smed_v6_14652_0_1, dd_Smed_v6_14652_0_1, [Score=152, Expect=8e-38]} {RNA1509_50571} {RNA1310_22156} {RNA815_40350.1}
49. MligTC455_14352 18 0.38 Mlig455_057678

Neo: -

Age: -

 0.976 - - - - 0.976 - Mlig455_057678 {REF} {Length: 2474} {NoTransDecoderORF} {RNA1509_25000} {RNA1310_23305} {RNA815_2326}
50. MligTC455_25813 14 0.28 Mlig455_001910

Neo: -

Age: -

 PPP1R16B 0.976 - - - - 0.976 - Mlig455_001910 {REF} {Length: 1899} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=101.6]; Ankyrin repeats (many copies) [PF13637.8, score=89.5]; Ankyrin repeat [PF00023.32, score=87.8]; Ankyrin repeat [PF13606.8, score=78.0]; Ankyrin repeats (many copies) [PF13857.8, score=76.1]} {Human: ENSG00000101445, PPP1R16B, protein phosphatase 1 regulatory subunit 16B, [Score=289, Expect=3e-91]} {Mouse: ENSMUSG00000037754, Ppp1r16b, protein phosphatase 1, regulatory subunit 16B, [Score=285, Expect=2e-89]; ENSMUSG00000033819, Ppp1r16a, protein phosphatase 1, regulatory subunit 16A, [Score=283, Expect=2e-89]} {Dmel: FBgn0036801, MYPT-75D, [Score=292, Expect=9e-92]} {Celegans: WBGene00001582, gfi-2, GEI-4 (Four) Interacting protein, [Score=231, Expect=2e-70]} {Smed: dd_Smed_v6_5941_0_2, dd_Smed_v6_5941_0_2, [Score=320, Expect=5e-104]} {RNA1310_118235}
51. MligTC455_49564 14 0.3 Mlig455_041658

Neo: -

Age: -

Region-enriched R4: 4.816/0.04533

 INSM2 0.976 - - - - 0.976 - Mlig455_041658 {REF} {Length: 1550} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=37.0]; C2H2-type zinc finger [PF13894.8, score=23.1]} {Human: ENSG00000168348, INSM2, INSM transcriptional repressor 2, [RH, Score=92.0, Expect=2e-19]; ENSG00000173404, INSM1, INSM transcriptional repressor 1, [RH, Score=89.0, Expect=2e-18]} {Mouse: ENSMUSG00000045440, Insm2, insulinoma-associated 2, [RH, Score=111, Expect=3e-26]} {Dmel: FBgn0028999, nerfin-1, nervous fingers 1, [RH, Score=154, Expect=7e-42]} {Celegans: WBGene00001210, egl-46, C2H2 zinc finger protein EGL-46, [RH, Score=108, Expect=1e-26]} {Smed: dd_Smed_v6_28888_0_1, dd_Smed_v6_28888_0_1, [RH, Score=108, Expect=8e-27]} {RNA1310_147090}
52. MligTC455_03471 12 0.26 Mlig455_070596

Neo: -

Age: logFC(26M/2M)=1.720

 0.975 - - - - 0.975 - Mlig455_070596 {REF} {Length: 4597} {RNA1509_21785} {RNA1310_51419} {RNA815_4932.1}
53. MligTC455_04182 14 0.29 Mlig455_026668

Neo: -

Age: -

 0.975 - - - - 0.975 - Mlig455_026668 {REF} {Length: 1235} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=21.2} {RNA1509_45595} {RNA1310_9218} {RNA815_6917.1}
54. MligTC455_12106 9 0.2 Mlig455_062451

Neo: -

Age: -

 0.975 - - - - 0.975 - Mlig455_062451 {REF} {Length: 1363} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=67.0]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=29.1]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=23.4]} {Smed: dd_Smed_v6_13742_0_1, dd_Smed_v6_13742_0_1, [Score=82.4, Expect=6e-18]} {RNA1310_95837}
55. MligTC455_22893 3 0.07 Mlig455_046046

Neo: -

Age: -

 AAK1 0.975 - - - - 0.975 - Mlig455_046046 {REF} {Length: 1298} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=40.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=18.6]} {Human: ENSG00000115977, AAK1, AP2 associated kinase 1, [Score=96.7, Expect=5e-23]} {Mouse: ENSMUSG00000057230, Aak1, AP2 associated kinase 1, [Score=95.5, Expect=9e-23]} {Dmel: FBgn0015772, Nak, Numb-associated kinase, [Score=80.9, Expect=8e-18]} {Celegans: WBGene00004762, sel-5, Serine/threonine-protein kinase sel-5, [Score=65.5, Expect=1e-12]} {Smed: dd_Smed_v6_6377_0_1, dd_Smed_v6_6377_0_1, [Score=113, Expect=2e-29]} {RNA1509_6873} {RNA1310_1788} {RNA815_10901}
56. MligTC455_32597 106 2.2 Mlig455_003631, Mlig455_033245

Neo: -

Age: -

 SSUH2 0.975 - - - - 0.975 -

Mlig455_003631 {REF} {Length: 1926} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=112, Expect=3e-27]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=73.2, Expect=5e-14]} {RNA1509_32165} {RNA1310_13450} {RNA815_5462.1}

Mlig455_033245 {REF} {Length: 3547} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=116, Expect=2e-28]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=75.9, Expect=9e-15]} {RNA1509_32165} {RNA1310_13450, RNA1509_32165} {RNA1509_32165, RNA815_5462.1}
57. MligTC455_56480 8 0.16 Mlig455_015107

Neo: -

Age: -

 0.975 - - - - 0.975 - Mlig455_015107 {REF} {Length: 546} {NoTransDecoderORF}
58. MligTC455_01886 11 0.22 Mlig455_022823, Mlig455_022932

Neo: -

Age: Down-Up-Down

 0.974 - - - - 0.974 -

Mlig455_022823 {REF} {Length: 93} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_40444} {RNA1310_2430.3} {RNA815_11228.1}

Mlig455_022932 {REF} {Length: 93} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_40444} {RNA1310_2430.3} {RNA815_11228.1}
59. MligTC455_53937 44 0.92 Mlig455_021975, Mlig455_022028

Neo: -

Age: -

 0.973 - - - - 0.973 -

Mlig455_021975 {REF} {Length: 631} {NoTransDecoderORF} {RNA1310_130902}

Mlig455_022028 {REF} {Length: 192} {NoTransDecoderORF} {RNA1310_130902}
60. MligTC455_12942 16 0.33 Mlig455_033008

Neo: -

Age: -

 CHRNA10 0.972 - - - - 0.972 - Mlig455_033008 {REF} {Length: 2331} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=183.6]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=55.8]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=7e-55]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=186, Expect=1e-53]; ENSG00000174343, CHRNA9, cholinergic receptor nicotinic alpha 9 subunit, [Score=185, Expect=5e-53]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=181, Expect=5e-51]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=181, Expect=5e-51]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=196, Expect=1e-57]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=180, Expect=3e-51]} {Celegans: WBGene00000050, acr-11, AcetylCholine Receptor, [Score=184, Expect=5e-53]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=214, Expect=7e-64]} {RNA1509_38665} {RNA1310_30702} {RNA815_28553}
61. MligTC455_14519 25 0.51 Mlig455_005304

Neo: -

Age: -

 0.972 - - - - 0.972 - Mlig455_005304 {REF} {Length: 1686} {RNA1509_3030} {RNA1310_65512} {RNA815_48423}
62. MligTC455_37747 25 0.53 Mlig455_024090

Neo: -

Age: -

Region-enriched R4: 6.148/0.01140

 0.972 - - - - 0.972 - Mlig455_024090 {REF} {Length: 223} {NoTransDecoderORF} {RNA1509_2515} {RNA1310_11167.1} {RNA815_3258.1}
63. MligTC455_44922 15 0.31 Mlig455_040611

Neo: -

Age: -

 AC254952.1 0.971 - - - - 0.971 - Mlig455_040611 {REF} {Length: 1658} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=86.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=85.3]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=1e-40]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=152, Expect=2e-40]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=147, Expect=9e-39]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=129, Expect=1e-32]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=136, Expect=2e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=136, Expect=2e-35]} {RNA1310_45581} {RNA815_21574}
64. MligTC455_52493 6 0.13 Mlig455_058213

Neo: -

Age: -

 0.97 - - - - 0.970 - Mlig455_058213 {REF} {Length: 1454} {Smed: dd_Smed_v6_25969_0_1, dd_Smed_v6_25969_0_1, [Score=79.0, Expect=3e-16]} {RNA1310_119010}
65. MligTC455_33257 441 9.18 Mlig455_032762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.898

Region-enriched R7: 7.302/0.00324

 ADAMTS1 0.969 - - - - 0.969 - Mlig455_032762 {REF} {Length: 2204} {Pfam: Metallo-peptidase family M12 [PF13688.8, score=49.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=41.2]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=41.1]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=35.5]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=29.0]; ADAM cysteine-rich domain [PF17771.3, score=25.4]} {Human: ENSG00000154734, ADAMTS1, ADAM metallopeptidase with thrombospondin type 1 motif 1, [Score=74.7, Expect=3e-13]; ENSG00000145808, ADAMTS19, ADAM metallopeptidase with thrombospondin type 1 motif 19, [Score=74.3, Expect=5e-13]} {Mouse: ENSMUSG00000006403, Adamts4, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, [Score=70.5, Expect=5e-12]; ENSMUSG00000022893, Adamts1, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1, [Score=68.9, Expect=2e-11]; ENSMUSG00000031994, Adamts8, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8, [Score=68.6, Expect=2e-11]; ENSMUSG00000053441, Adamts19, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19, [Score=68.6, Expect=2e-11]} {Dmel: FBgn0034903, sona, sol narae, [Score=73.2, Expect=5e-13]} {Celegans: WBGene00003248, mig-17, ADAM family mig-17, [Score=57.0, Expect=3e-08]} {RNA1509_380} {RNA1310_14719} {RNA815_5216}
66. MligTC455_37593 287 5.97 Mlig455_042409

Neo: -

Age: -

 0.967 - - - - 0.967 - Mlig455_042409 {REF} {Length: 908} {NoTransDecoderORF} {RNA1509_55800} {RNA1310_92496} {RNA815_54171}
67. MligTC455_05701 250 5.21 Mlig455_020813

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.791

Region-enriched R7: 4.270/0.02152

 CTSA 0.966 - - - 0.966 - - Mlig455_020813 {REF} {Length: 1956} {Pfam: Serine carboxypeptidase [PF00450.24, score=286.5]} {Human: ENSG00000064601, CTSA, cathepsin A, [Score=192, Expect=4e-55]} {Mouse: ENSMUSG00000017760, Ctsa, cathepsin A, [Score=185, Expect=1e-52]} {Dmel: FBgn0038738, CG4572, [RH, Score=115, Expect=2e-27]} {Celegans: WBGene00019605, ctsa-1, Uncharacterized serine carboxypeptidase ctsa-1, [Score=189, Expect=2e-54]} {Smed: dd_Smed_v6_785_0_1, dd_Smed_v6_785_0_1, [Score=201, Expect=7e-59]} {RNA1509_59882} {RNA1310_13629, RNA1509_59882} {RNA1509_59882, RNA815_3781}
68. MligTC455_25379 147 3.07 Mlig455_044596

Neo: -

Age: logFC(26M/2M)=0.621

 TNS2 0.966 - - - - 0.966 - Mlig455_044596 {REF} {Length: 2665} {Pfam: SH2 domain [PF00017.26, score=29.8]; Phosphotyrosine-binding domain [PF08416.15, score=22.5]} {Human: ENSG00000111077, TNS2, tensin 2, [Score=96.7, Expect=3e-20]} {Mouse: ENSMUSG00000037003, Tns2, tensin 2, [Score=89.0, Expect=5e-18]} {Smed: dd_Smed_v6_4454_0_2, dd_Smed_v6_4454_0_2, [Score=97.1, Expect=5e-21]} {RNA1509_44612} {RNA1310_9162.1} {RNA815_10953}
69. MligTC455_27186 28 0.57 Mlig455_010236

Neo: -

Age: logFC(26M/2M)=-1.855

 0.966 - - - - 0.966 - Mlig455_010236 {REF} {Length: 486} {RNA1509_7146} {RNA1310_76234.2} {RNA815_34947.2}
70. MligTC455_31114 53 1.1 Mlig455_017272

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.386

 SLC10A2 0.966 - - - - 0.966 - Mlig455_017272 {REF} {Length: 2348} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=113.6]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=38.7]} {Human: ENSG00000125255, SLC10A2, solute carrier family 10 member 2, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [RH, Score=155, Expect=7e-43]} {Dmel: FBgn0030638, CG11655, [Score=157, Expect=7e-43]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=180, Expect=9e-51]} {Smed: dd_Smed_v6_14676_0_1, dd_Smed_v6_14676_0_1, [Score=260, Expect=5e-82]} {RNA1509_52848} {RNA1310_31875.1} {RNA815_14501}
71. MligTC455_48064 23 0.48 Mlig455_061550

Neo: -

Age: -

 0.965 - - - - 0.965 - Mlig455_061550 {REF} {Length: 860} {RNA1310_88363} {RNA815_47885}
72. MligTC455_54350 200 4.17 Mlig455_008866

Neo: -

Age: -

 PLAC8 0.965 - - - - 0.965 - Mlig455_008866 {REF} {Length: 1137} {Pfam: PLAC8 family [PF04749.19, score=73.9]} {Human: ENSG00000145287, PLAC8, placenta specific 8, [Score=53.1, Expect=7e-10]} {Smed: dd_Smed_v6_477_0_1, dd_Smed_v6_477_0_1, [RH, Score=127, Expect=2e-39]} {RNA1509_49668} {RNA1310_34433, RNA1509_49668} {RNA1509_49668, RNA815_23736}
73. MligTC455_04618 22 0.46 Mlig455_061990

Neo: -

Age: -

 AVPR1A 0.963 - - - - 0.963 - Mlig455_061990 {REF} {Length: 2747} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=128.1]} {Human: ENSG00000166148, AVPR1A, arginine vasopressin receptor 1A, [Score=126, Expect=1e-31]; ENSG00000198049, AVPR1B, arginine vasopressin receptor 1B, [Score=126, Expect=1e-31]; ENSG00000187258, NPSR1, neuropeptide S receptor 1, [Score=120, Expect=1e-29]} {Mouse: ENSMUSG00000043659, Npsr1, neuropeptide S receptor 1, [Score=126, Expect=2e-32]; ENSMUSG00000020123, Avpr1a, arginine vasopressin receptor 1A, [Score=122, Expect=2e-30]} {Dmel: FBgn0039396, CCAP-R, Crustacean cardioactive peptide receptor, [RH, Score=174, Expect=3e-49]} {Celegans: WBGene00011582, ntr-1, Nematocin receptor 1, [Score=73.9, Expect=3e-14]} {Smed: dd_Smed_v6_35162_0_1, dd_Smed_v6_35162_0_1, [Score=138, Expect=9e-37]} {RNA1310_24450} {RNA815_41610}
74. MligTC455_33853 7 0.14 Mlig455_029940

Neo: -

Age: -

 MGAT1 0.963 - - - - 0.963 - Mlig455_029940 {REF} {Length: 2088} {Pfam: GNT-I family [PF03071.17, score=204.9]} {Human: ENSG00000131446, MGAT1, mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, [Score=153, Expect=4e-41]} {Mouse: ENSMUSG00000020346, Mgat1, mannoside acetylglucosaminyltransferase 1, [Score=166, Expect=4e-46]} {Dmel: FBgn0034521, Mgat1, Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1, [Score=172, Expect=3e-48]} {Celegans: WBGene00001639, gly-14, GLYcosylation related; UDP-N-acetylglucosamine:a-3-D-mannoside b-1,2-N-acetylglucosaminyltransferase I, [Score=144, Expect=2e-38]} {Smed: dd_Smed_v6_13024_0_1, dd_Smed_v6_13024_0_1, [Score=158, Expect=1e-43]} {RNA1310_114996}
75. MligTC455_06568 11 0.22 Mlig455_028459

Neo: -

Age: -

 0.962 - - - - 0.962 - Mlig455_028459 {REF} {Length: 1484} {Pfam: Lectin C-type domain [PF00059.23, score=32.8]} {RNA1310_143218}
76. MligTC455_06260 8 0.16 Mlig455_047053

Neo: -

Age: -

 GRM3 0.961 - - - - 0.961 - Mlig455_047053 {REF} {Length: 3518} {Pfam: Receptor family ligand binding region [PF01094.30, score=246.1]; 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=181.7]; Nine Cysteines Domain of family 3 GPCR [PF07562.16, score=29.0]; Periplasmic binding protein [PF13458.8, score=22.4]} {Human: ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=551, Expect=0.0]; ENSG00000196277, GRM7, glutamate metabotropic receptor 7, [Score=545, Expect=4e-178]; ENSG00000179603, GRM8, glutamate metabotropic receptor 8, [Score=541, Expect=5e-177]} {Mouse: ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=547, Expect=9e-180]; ENSMUSG00000024211, Grm8, glutamate receptor, metabotropic 8, [Score=544, Expect=3e-178]; ENSMUSG00000056755, Grm7, glutamate receptor, metabotropic 7, [Score=541, Expect=6e-177]; ENSMUSG00000023192, Grm2, glutamate receptor, metabotropic 2, [Score=530, Expect=4e-173]; ENSMUSG00000063239, Grm4, glutamate receptor, metabotropic 4, [Score=524, Expect=2e-170]} {Dmel: FBgn0050361, mtt, mangetout, [RH, Score=849, Expect=0.0]} {Celegans: WBGene00003232, mgl-1, Probable metabotropic glutamate receptor mgl-1, [Score=521, Expect=6e-169]} {Smed: dd_Smed_v6_15419_0_1, dd_Smed_v6_15419_0_1, [Score=493, Expect=5e-157]} {RNA1310_22509}
77. MligTC455_08774 25 0.53 Mlig455_001889

Neo: -

Age: Up-Down-Down

 HCRTR2 0.96 - - - - 0.960 - Mlig455_001889 {REF} {Length: 3436} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=160.6]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.4]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=24.1]} {Human: ENSG00000137252, HCRTR2, hypocretin receptor 2, [RH, Score=215, Expect=2e-63]} {Mouse: ENSMUSG00000032360, Hcrtr2, hypocretin (orexin) receptor 2, [RH, Score=212, Expect=1e-62]} {Dmel: FBgn0038874, ETHR, [Score=142, Expect=6e-37]} {Celegans: WBGene00013974, npr-9, Galanin-like G-protein coupled receptor npr-9, [Score=116, Expect=6e-28]} {Smed: dd_Smed_v6_22624_0_1, dd_Smed_v6_22624_0_1, [RH, Score=202, Expect=1e-59]} {RNA1310_31833} {RNA815_15909}
78. MligTC455_22214 237 4.94 Mlig455_019333, Mlig455_019447

Neo: -

Age: -

 NRG2 0.96 - - - - 0.960 -

Mlig455_019333 {REF} {Length: 4291} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.7]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.0]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=86.7, Expect=8e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=81.3, Expect=2e-15]} {Dmel: FBgn0005666, bt, bent, [Score=52.0, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}

Mlig455_019447 {REF} {Length: 4242} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.8]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.1]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=18.6]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=88.6, Expect=2e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=83.2, Expect=7e-16]} {Dmel: FBgn0005666, bt, bent, [Score=52.4, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}
79. MligTC455_26101 65 1.35 Mlig455_036947

Neo: -

Age: -

 0.958 - - - - 0.958 - Mlig455_036947 {REF} {Length: 2415} {RNA1509_51525} {RNA1310_9237.1} {RNA815_5309}
80. MligTC455_27535 13 0.27 Mlig455_048809

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=1.142

 PPP1R16B 0.958 - - - - 0.958 - Mlig455_048809 {REF} {Length: 2464} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=99.6]; Ankyrin repeat [PF00023.32, score=86.5]; Ankyrin repeats (many copies) [PF13637.8, score=86.4]; Ankyrin repeats (many copies) [PF13857.8, score=75.5]; Ankyrin repeat [PF13606.8, score=75.2]} {Human: ENSG00000101445, PPP1R16B, protein phosphatase 1 regulatory subunit 16B, [Score=286, Expect=1e-88]} {Mouse: ENSMUSG00000037754, Ppp1r16b, protein phosphatase 1, regulatory subunit 16B, [Score=280, Expect=9e-87]; ENSMUSG00000033819, Ppp1r16a, protein phosphatase 1, regulatory subunit 16A, [Score=278, Expect=2e-86]} {Dmel: FBgn0036801, MYPT-75D, [Score=291, Expect=2e-90]} {Celegans: WBGene00001582, gfi-2, GEI-4 (Four) Interacting protein, [Score=228, Expect=7e-68]} {Smed: dd_Smed_v6_5941_0_2, dd_Smed_v6_5941_0_2, [Score=311, Expect=4e-99]} {RNA1310_118235}
81. MligTC455_39202 47 0.99 Mlig455_010593

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.010/0.00677
Region-enriched R7: 4.029/0.03663

 CALM2 0.957 - - - - 0.957 - Mlig455_010593 {REF} {Length: 1658} {Pfam: EF hand [PF00036.34, score=125.1]; EF-hand domain pair [PF13499.8, score=116.7]; EF-hand domain pair [PF13833.8, score=96.2]; EF-hand domain [PF13405.8, score=93.9]; EF hand [PF13202.8, score=88.5]; EF-hand domain [PF14658.8, score=36.7]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=31.9]; Tellurite resistance protein TerB [PF05099.15, score=30.3]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=28.7]; Caleosin related protein [PF05042.15, score=24.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=200, Expect=5e-65]; ENSG00000160014, CALM3, calmodulin 3, [Score=198, Expect=8e-65]; ENSG00000198668, CALM1, calmodulin 1, [Score=198, Expect=7e-65]; ENSG00000178363, CALML3, calmodulin like 3, [Score=190, Expect=1e-61]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=203, Expect=3e-66]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=198, Expect=5e-65]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=198, Expect=5e-65]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=199, Expect=3e-65]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=199, Expect=2e-65]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=199, Expect=2e-65]} {RNA1509_58569} {RNA1310_33205} {RNA815_15087}
82. MligTC455_16334 23 0.47 Mlig455_048897

Neo: -

Age: -

 GABBR2 0.956 - - - - 0.956 - Mlig455_048897 {REF} {Length: 2632} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=156.6]; Receptor family ligand binding region [PF01094.30, score=109.3]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=307, Expect=2e-91]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=306, Expect=2e-91]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=267, Expect=5e-76]} {Celegans: WBGene00021528, gbb-1, GABA B receptor subunit; GABAB1 receptor subunit, [Score=234, Expect=4e-66]} {Smed: dd_Smed_v6_51663_0_1, dd_Smed_v6_51663_0_1, [Score=129, Expect=2e-33]} {RNA1509_38426} {RNA1310_30172} {RNA815_43578}
83. MligTC455_53466 67 1.39 Mlig455_070695

Neo: -

Age: Up-Down-Down

 0.956 - - - - 0.956 - Mlig455_070695 {REF} {Length: 2622} {Pfam: PDZ domain [PF00595.26, score=27.1]} {RNA1310_42258} {RNA815_27727}
84. MligTC455_20890 29 0.6 Mlig455_001461

Neo: -

Age: Down-Down-Up

 0.955 - - - - 0.955 - Mlig455_001461 {REF} {Length: 2259} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=39.9]} {Smed: dd_Smed_v6_42201_0_1, dd_Smed_v6_42201_0_1, [Score=87.4, Expect=6e-19]} {RNA1310_44182}
85. MligTC455_06678 10 0.22 Mlig455_051040

Neo: -

Age: -

 SLC7A1 0.954 - - - 0.954 - - Mlig455_051040 {REF} {Length: 1969} {Pfam: Amino acid permease [PF13520.8, score=122.2]; Amino acid permease [PF00324.23, score=107.8]; C-terminus of AA_permease [PF13906.8, score=56.1]} {Human: ENSG00000139514, SLC7A1, solute carrier family 7 member 1, [Score=297, Expect=3e-92]} {Mouse: ENSMUSG00000041313, Slc7a1, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1, [Score=300, Expect=2e-93]; ENSMUSG00000022756, Slc7a4, solute carrier family 7 (cationic amino acid transporter, y+ system), member 4, [Score=297, Expect=3e-92]; ENSMUSG00000054753, AU018091, expressed sequence AU018091, [Score=290, Expect=5e-89]; ENSMUSG00000107871, AU018091, expressed sequence AU018091, [Score=290, Expect=5e-89]} {Dmel: FBgn0036984, CG13248, [Score=290, Expect=1e-89]} {Celegans: WBGene00016806, C50D2.2, [Score=293, Expect=1e-91]} {Smed: dd_Smed_v6_8652_0_4, dd_Smed_v6_8652_0_4, [Score=436, Expect=3e-147]} {RNA1310_82370} {RNA815_51664}
86. MligTC455_19938 250 5.2 Mlig455_063706

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.458

Region-enriched R3: 3.513/0.03723

 NKX2-2 0.953 - - - 0.953 - - Mlig455_063706 {REF} {Length: 2739} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=3e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=2e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.9, Expect=8e-23]} {Smed: dd_Smed_v6_2716_0_4, dd_Smed_v6_2716_0_4, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1, RNA1509_27298} {RNA1509_27298, RNA815_30453}
87. MligTC455_29466 109 2.27 Mlig455_042901

Neo: -

Age: -

 MADD 0.953 - - - - 0.953 - Mlig455_042901 {REF} {Length: 6527} {TRANSSPLICED} {Pfam: DENN (AEX-3) domain [PF02141.23, score=81.5]} {Human: ENSG00000110514, MADD, MAP kinase activating death domain, [Score=431, Expect=2e-126]} {Mouse: ENSMUSG00000040687, Madd, MAP-kinase activating death domain, [Score=835, Expect=0.0]} {Dmel: FBgn0030613, Rab3-GEF, Rab3 GDP-GTP exchange factor, [Score=375, Expect=3e-106]} {Celegans: WBGene00000086, aex-3, MAP kinase-activating death domain protein, [Score=328, Expect=6e-92]} {Smed: dd_Smed_v6_8355_0_9, dd_Smed_v6_8355_0_9, [Score=906, Expect=0.0]} {RNA1509_39762} {RNA1310_1472.2} {RNA815_2999.1}
88. MligTC455_01991 81 1.7 Mlig455_065021

Neo: -

Age: -

 0.952 - - - - 0.952 - Mlig455_065021 {REF} {Length: 975} {Pfam: Ammonium Transporter Family [PF00909.23, score=41.4]} {Dmel: FBgn0038309, Amt, Ammonium transporter, [Score=49.3, Expect=5e-07]} {Celegans: WBGene00000134, amt-2, Putative ammonium transporter 2, [Score=52.8, Expect=3e-08]}
89. MligTC455_03801 18 0.38 Mlig455_017135

Neo: -

Age: -

 0.952 - - - - 0.952 - Mlig455_017135 {REF} {Length: 441} {NoTransDecoderORF} {RNA1509_33446} {RNA1310_9913} {RNA815_13562.1}
90. MligTC455_09535 21 0.44 Mlig455_045585

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.720

 0.952 - - - - 0.952 - Mlig455_045585 {REF} {Length: 3644} {RNA1310_75578} {RNA815_42836.2}
91. MligTC455_15253 11 0.22 Mlig455_010266

Neo: -

Age: -

 0.952 - - - - 0.952 - Mlig455_010266 {REF} {Length: 252} {NoTransDecoderORF} {RNA815_48483}
92. MligTC455_25323 440 9.16 Mlig455_044300

Neo: -

Age: -

 0.952 - - - - 0.952 - Mlig455_044300 {REF} {Length: 4648} {Pfam: DDE superfamily endonuclease [PF13358.8, score=47.2]} {Dmel: FBgn0263076, Klp54D, Kinesin-like protein at 54D, [Score=76.6, Expect=7e-14]} {Smed: dd_Smed_v6_15852_0_1, dd_Smed_v6_15852_0_1, [Score=106, Expect=1e-24]} {RNA1509_56341} {RNA1310_5922.1} {RNA815_12097}
93. MligTC455_40051 36 0.76 Mlig455_025990

Neo: -

Age: logFC(26M/2M)=-0.633

 PRKCE 0.952 - - - - 0.952 - Mlig455_025990 {REF} {Length: 2622} {Pfam: Protein kinase domain [PF00069.27, score=102.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=69.5]; Kinase-like [PF14531.8, score=19.5]} {Human: ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=84.3, Expect=1e-16]} {Mouse: ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=82.0, Expect=5e-16]} {Dmel: FBgn0283472, S6k, Ribosomal protein S6 kinase, [Score=79.0, Expect=2e-15]} {Celegans: WBGene00009793, pkn-1, Protein Kinase N (PKN) homolog, [Score=73.2, Expect=2e-13]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=77.8, Expect=4e-15]} {RNA1509_36146} {RNA1310_24732} {RNA815_64704}
94. MligTC455_55235 5 0.1 Mlig455_059236

Neo: -

Age: -

 0.952 - - - - 0.952 - Mlig455_059236 {REF} {Length: 166} {NoTransDecoderORF}
95. MligTC455_34692 37 0.77 Mlig455_017379

Neo: -

Age: -

 0.951 - - - 0.951 - - Mlig455_017379 {REF} {Length: 579} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_10294} {RNA1310_2672} {RNA815_25099}
96. MligTC455_40490 6 0.12 Mlig455_041034

Neo: -

Age: -

 PTPRG 0.95 - - - - 0.950 - Mlig455_041034 {REF} {Length: 5196} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=281.6]; Fibronectin type III domain [PF00041.23, score=71.3]; Immunoglobulin V-set domain [PF07686.19, score=25.9]} {Human: ENSG00000144724, PTPRG, protein tyrosine phosphatase, receptor type G, [Score=298, Expect=4e-82]; ENSG00000106278, PTPRZ1, protein tyrosine phosphatase, receptor type Z1, [Score=284, Expect=2e-77]} {Mouse: ENSMUSG00000021745, Ptprg, protein tyrosine phosphatase, receptor type, G, [Score=291, Expect=7e-80]; ENSMUSG00000068748, Ptprz1, protein tyrosine phosphatase, receptor type Z, polypeptide 1, [Score=280, Expect=6e-76]} {Dmel: FBgn0004369, Ptp99A, Protein tyrosine phosphatase 99A, [Score=277, Expect=2e-77]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=231, Expect=1e-61]} {Smed: dd_Smed_v6_6997_0_1, dd_Smed_v6_6997_0_1, [Score=292, Expect=9e-81]} {RNA1310_83388} {RNA815_43661}
97. MligTC455_46761 1116 23.26 Mlig455_063765

Neo: -

Age: logFC(26M/2M)=0.304

 SLC1A2 0.95 - - - - 0.950 - Mlig455_063765 {REF} {Length: 3371} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=425.5]} {Human: ENSG00000110436, SLC1A2, solute carrier family 1 member 2, [RH, Score=534, Expect=0.0]} {Mouse: ENSMUSG00000005089, Slc1a2, solute carrier family 1 (glial high affinity glutamate transporter), member 2, [RH, Score=545, Expect=0.0]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=382, Expect=5e-127]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [RH, Score=532, Expect=0.0]} {Smed: dd_Smed_v6_7570_0_1, dd_Smed_v6_7570_0_1, [RH, Score=607, Expect=0.0]} {RNA1509_2356} {RNA1310_5021.1} {RNA815_1444.1}
98. MligTC455_50203 99 2.07 Mlig455_069536

Neo: -

Age: -

Region-enriched R2: 3.355/0.02064

 DOC2B 0.95 - - - - 0.950 - Mlig455_069536 {REF} {Length: 3698} {Pfam: C2 domain [PF00168.32, score=136.9]; FYVE-type zinc finger [PF02318.18, score=43.7]} {Human: ENSG00000272670, DOC2B, double C2 domain beta, [Score=241, Expect=3e-73]; ENSG00000272636, DOC2B, double C2 domain beta, [Score=241, Expect=4e-73]; ENSG00000089169, RPH3A, rabphilin 3A, [Score=236, Expect=1e-68]; ENSG00000149927, DOC2A, double C2 domain alpha, [Score=231, Expect=1e-69]} {Mouse: ENSMUSG00000029608, Rph3a, rabphilin 3A, [RH, Score=234, Expect=7e-68]} {Dmel: FBgn0030230, Rph, Rabphilin, [Score=186, Expect=1e-52]} {Celegans: WBGene00004316, rbf-1, Rabphilin-1, [RH, Score=222, Expect=5e-62]} {Smed: dd_Smed_v6_12977_0_1, dd_Smed_v6_12977_0_1, [Score=289, Expect=1e-89]} {RNA1509_54585} {RNA1310_23959} {RNA815_21115}

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