Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_51774 | 143 | 2.99 | Mlig455_020123 | Neo: - Age: - Region-enriched R6: 2.569/0.02780 |
POU3F3 | Mlig455_020123 {REF} {Length: 5804} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=128.2]; Homeodomain [PF00046.31, score=64.9]} {Human: ENSG00000198914, POU3F3, POU class 3 homeobox 3, [RH, Score=291, Expect=1e-91]; ENSG00000184486, POU3F2, POU class 3 homeobox 2, [RH, Score=288, Expect=5e-91]; ENSG00000196767, POU3F4, POU class 3 homeobox 4, [RH, Score=286, Expect=1e-91]; ENSG00000185668, POU3F1, POU class 3 homeobox 1, [RH, Score=284, Expect=2e-89]} {Mouse: ENSMUSG00000045515, Pou3f3, POU domain, class 3, transcription factor 3, [RH, Score=291, Expect=7e-92]; ENSMUSG00000095139, Pou3f2, POU domain, class 3, transcription factor 2, [RH, Score=288, Expect=4e-91]; ENSMUSG00000056854, Pou3f4, POU domain, class 3, transcription factor 4, [RH, Score=287, Expect=6e-92]; ENSMUSG00000090125, Pou3f1, POU domain, class 3, transcription factor 1, [RH, Score=283, Expect=2e-89]} {Dmel: FBgn0086680, vvl, ventral veins lacking, [RH, Score=293, Expect=5e-90]} {Celegans: WBGene00000431, ceh-6, Homeobox protein ceh-6, [RH, Score=247, Expect=2e-76]} {Smed: dd_Smed_v6_8234_0_1, dd_Smed_v6_8234_0_1, [RH, Score=270, Expect=1e-84]} {RNA1509_24966} {RNA1310_6220} {RNA815_1267} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -4.467 | 2.24 | 0.38618 | 1.00000 | |
RegionR2 | 1.522 | 2.24 | 0.17290 | 0.51984 | |
RegionR3 | 0.006 | 2.24 | 0.85566 | 1.00000 | |
RegionR4 | -1.116 | 2.24 | 0.99121 | 1.00000 | |
RegionR5 | -0.922 | 2.24 | 0.98595 | 1.00000 | |
RegionR6 | 2.569 | 2.24 | 0.00060 | 0.02780 | |
RegionR7 | 1.039 | 2.24 | 0.43043 | 1.00000 | |
RegionR8 | 1.368 | 2.24 | 0.39317 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.601 | 2.24 | 0.99995 | 1.00000 | |
RegenerationR2 | 0.047 | 2.24 | 0.94372 | 1.00000 | |
RegenerationR3 | 0.718 | 2.24 | 0.38232 | 0.79163 | |
RegenerationR4 | 0.97 | 2.24 | 0.24332 | 0.69131 | |
RegenerationR5 | 0.534 | 2.24 | 0.49684 | 0.85705 | |
RegenerationR6 | -0.653 | 2.24 | 0.30494 | 0.65400 | |
RegenerationBL | 0.065 | 2.24 | 0.95180 | 1.00000 | |
RegenerationTP | -0.308 | 2.24 | 0.78529 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_51774 | 143 | 2.99 | Mlig455_020123 | Neo: - Age: - Region-enriched R6: 2.569/0.02780 |
POU3F3 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_020123 {REF} {Length: 5804} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=128.2]; Homeodomain [PF00046.31, score=64.9]} {Human: ENSG00000198914, POU3F3, POU class 3 homeobox 3, [RH, Score=291, Expect=1e-91]; ENSG00000184486, POU3F2, POU class 3 homeobox 2, [RH, Score=288, Expect=5e-91]; ENSG00000196767, POU3F4, POU class 3 homeobox 4, [RH, Score=286, Expect=1e-91]; ENSG00000185668, POU3F1, POU class 3 homeobox 1, [RH, Score=284, Expect=2e-89]} {Mouse: ENSMUSG00000045515, Pou3f3, POU domain, class 3, transcription factor 3, [RH, Score=291, Expect=7e-92]; ENSMUSG00000095139, Pou3f2, POU domain, class 3, transcription factor 2, [RH, Score=288, Expect=4e-91]; ENSMUSG00000056854, Pou3f4, POU domain, class 3, transcription factor 4, [RH, Score=287, Expect=6e-92]; ENSMUSG00000090125, Pou3f1, POU domain, class 3, transcription factor 1, [RH, Score=283, Expect=2e-89]} {Dmel: FBgn0086680, vvl, ventral veins lacking, [RH, Score=293, Expect=5e-90]} {Celegans: WBGene00000431, ceh-6, Homeobox protein ceh-6, [RH, Score=247, Expect=2e-76]} {Smed: dd_Smed_v6_8234_0_1, dd_Smed_v6_8234_0_1, [RH, Score=270, Expect=1e-84]} {RNA1509_24966} {RNA1310_6220} {RNA815_1267} |
2. | MligTC455_48257 | 51 | 1.07 | Mlig455_020980 | Neo: - Age: - |
VAV3 | 1.83 | - | - | - | - | 0.870 | 0.960 | Mlig455_020980 {REF} {Length: 3664} {Pfam: Calponin homology (CH) domain [PF00307.33, score=41.6]; RhoGEF domain [PF00621.22, score=39.8]; SH2 domain [PF00017.26, score=27.7]; CAMSAP CH domain [PF11971.10, score=20.9]} {Human: ENSG00000134215, VAV3, vav guanine nucleotide exchange factor 3, [Score=135, Expect=5e-32]; ENSG00000160293, VAV2, vav guanine nucleotide exchange factor 2, [Score=134, Expect=1e-31]} {Mouse: ENSMUSG00000009621, Vav2, vav 2 oncogene, [Score=134, Expect=8e-32]; ENSMUSG00000033721, Vav3, vav 3 oncogene, [Score=132, Expect=3e-31]} {Celegans: WBGene00006887, vav-1, [Score=107, Expect=9e-24]} {Smed: dd_Smed_v6_6109_0_1, dd_Smed_v6_6109_0_1, [Score=97.1, Expect=1e-20]} {RNA1310_24185} {RNA815_29420} |
3. | MligTC455_48862 | 115 | 2.4 | Mlig455_045259 | Neo: - Age: Up-Down-Up |
TTN | 1.782 | - | - | 0.817 | - | 0.965 | - | Mlig455_045259 {REF} {Length: 3317} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=230.4]; Immunoglobulin domain [PF13927.8, score=132.2]; Immunoglobulin domain [PF00047.27, score=87.0]; Immunoglobulin domain [PF13895.8, score=84.9]; Immunoglobulin V-set domain [PF07686.19, score=42.4]; Immunoglobulin C1-set domain [PF07654.17, score=24.1]} {Human: ENSG00000155657, TTN, titin, [Score=107, Expect=1e-22]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=123, Expect=6e-28]} {Dmel: FBgn0086906, sls, sallimus, [Score=337, Expect=2e-97]} {Celegans: WBGene00004130, ketn-1, KETtiN (Drosophila actin-binding) homolog; Kettin, [Score=278, Expect=7e-78]} {Smed: dd_Smed_v6_2928_0_1, dd_Smed_v6_2928_0_1, [RH, Score=534, Expect=2e-177]} {RNA1509_11032} {RNA1310_1392.2} {RNA815_689.1} |
4. | MligTC455_07923 | 371 | 7.73 | Mlig455_035667 | Neo: - Age: Down-Up-Down Region-enriched R6: 5.311/0.00000 |
OSR2 | 1.76 | 0.801 | - | - | - | - | 0.959 | Mlig455_035667 {REF} {Length: 972} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=53.1]; C2H2-type zinc finger [PF13894.8, score=39.0]; Zinc-finger double domain [PF13465.8, score=36.6]; C2H2-type zinc finger [PF13912.8, score=26.5]} {Human: ENSG00000164920, OSR2, odd-skipped related transciption factor 2, [Score=157, Expect=9e-45]; ENSG00000143867, OSR1, odd-skipped related transciption factor 1, [Score=157, Expect=6e-45]} {Mouse: ENSMUSG00000048387, Osr1, odd-skipped related transcription factor 1, [Score=157, Expect=5e-45]; ENSMUSG00000022330, Osr2, odd-skipped related 2, [Score=156, Expect=1e-44]} {Dmel: FBgn0002985, odd, odd skipped, [RH, Score=161, Expect=2e-45]} {Celegans: WBGene00003846, odd-2, Protein odd-skipped-related 2, [RH, Score=161, Expect=6e-47]} {Smed: dd_Smed_v6_10039_0_1, dd_Smed_v6_10039_0_1, [Score=172, Expect=8e-51]} {RNA1509_57522} {RNA1310_42919} {RNA815_20495} |
5. | MligTC455_36023 | 124 | 2.58 | Mlig455_051287 | Neo: - Age: - |
TRPM3 | 1.715 | 0.972 | - | - | 0.743 | - | - | Mlig455_051287 {REF} {Length: 4788} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.0]; Ion transport protein [PF00520.33, score=63.8]; Ankyrin repeats (many copies) [PF13637.8, score=55.2]; Ankyrin repeat [PF00023.32, score=44.1]; Ankyrin repeats (many copies) [PF13857.8, score=42.4]; Ankyrin repeat [PF13606.8, score=30.9]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=152, Expect=2e-36]; ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=148, Expect=4e-35]; ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=148, Expect=4e-35]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=153, Expect=7e-37]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=146, Expect=9e-35]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=129, Expect=1e-29]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=104, Expect=2e-22]} {Smed: dd_Smed_v6_17981_0_2, dd_Smed_v6_17981_0_2, [Score=195, Expect=3e-50]} {RNA1509_36155} {RNA1310_16055, RNA1509_36155} {RNA1509_36155, RNA815_25933} |
6. | MligTC455_31770 | 61 | 1.27 | Mlig455_026049 | Neo: - Age: Up-Down-Down |
TRIM3 | 0.968 | 0.968 | - | - | - | - | - | Mlig455_026049 {REF} {Length: 6214} {TRANSSPLICED} {Pfam: NHL repeat [PF01436.23, score=19.2]} {Human: ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=55.5, Expect=2e-07]} {Mouse: ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=55.5, Expect=1e-07]} {RNA1509_23300} {RNA1310_24008.1} {RNA815_3900.1} |
7. | MligTC455_35333 | 90 | 1.87 | Mlig455_067763 | Neo: - Age: - |
RPS6KB1 | 0.968 | - | - | - | 0.968 | - | - | Mlig455_067763 {REF} {Length: 2200} {Pfam: Protein kinase domain [PF00069.27, score=227.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.1]; Protein kinase C terminal domain [PF00433.26, score=39.1]; Kinase-like [PF14531.8, score=30.7]} {Human: ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [Score=453, Expect=2e-155]; ENSG00000175634, RPS6KB2, ribosomal protein S6 kinase B2, [Score=441, Expect=2e-150]} {Mouse: ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=452, Expect=2e-154]; ENSMUSG00000097721, Rps6kb2, ribosomal protein S6 kinase, polypeptide 2, [Score=431, Expect=1e-146]; ENSMUSG00000024830, Rps6kb2, ribosomal protein S6 kinase, polypeptide 2, [Score=431, Expect=1e-146]} {Dmel: FBgn0283472, S6k, Ribosomal protein S6 kinase, [Score=437, Expect=5e-149]} {Celegans: WBGene00012929, rsks-1, Ribosomal protein S6 kinase beta, [Score=427, Expect=2e-144]} {Smed: dd_Smed_v6_5658_0_1, dd_Smed_v6_5658_0_1, [RH, Score=466, Expect=2e-160]} {RNA1509_36368} {RNA1310_14771.1} {RNA815_3550} |
8. | MligTC455_37009 | 39 | 0.82 | Mlig455_057445 | Neo: - Age: - |
0.967 | 0.967 | - | - | - | - | - | Mlig455_057445 {REF} {Length: 1385} {NoTransDecoderORF} {RNA1509_51521} {RNA1310_2201} {RNA815_40192} | |
9. | MligTC455_22287 | 217 | 4.51 | Mlig455_061243 | Neo: - Age: - Region-enriched R6: 2.653/0.03497 |
0.963 | 0.963 | - | - | - | - | - | Mlig455_061243 {REF} {Length: 715} {RNA1310_30275.2} {RNA815_15340.1} | |
10. | MligTC455_49144 | 224 | 4.67 | Mlig455_067459 | Neo: - Age: - Region-enriched R4: 3.068/0.01719 |
0.958 | 0.958 | - | - | - | - | - | Mlig455_067459 {REF} {Length: 2398} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=49.5]} {Smed: dd_Smed_v6_13233_0_2, dd_Smed_v6_13233_0_2, [Score=60.1, Expect=3e-09]} {RNA1509_11962} {RNA1310_8951.1} | |
11. | MligTC455_48256 | 51 | 1.07 | Mlig455_007665 | Neo: - Age: Down-Up-Down |
0.956 | - | - | - | - | - | 0.956 | Mlig455_007665 {REF} {Length: 4291} {Pfam: EF-hand domain pair [PF13833.8, score=30.9]; EF hand [PF00036.34, score=25.2]; EF-hand domain pair [PF13499.8, score=21.4]; RhoGEF domain [PF00621.22, score=21.0]; EF hand [PF13202.8, score=18.1]} {RNA1509_8417} {RNA1310_24185} {RNA815_18042.1} | |
12. | MligTC455_10723 | 27 | 0.55 | Mlig455_025988 | Neo: - Age: - |
0.952 | 0.952 | - | - | - | - | - | Mlig455_025988 {REF} {Length: 511} {NoTransDecoderORF} {RNA1509_42786} {RNA1310_26614} {RNA815_15996} | |
13. | MligTC455_35002 | 390 | 8.12 | Mlig455_070372 | Neo: - |
SVEP1 | 0.951 | 0.951 | - | - | - | - | - | Mlig455_070372 {REF} {Length: 1042} {Pfam: EGF-like domain [PF00008.29, score=33.8]; EGF-like domain [PF07974.15, score=21.9]} {Human: ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=51.6, Expect=3e-07]; ENSG00000148400, NOTCH1, notch 1, [Score=51.2, Expect=4e-07]} {Mouse: ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=58.9, Expect=5e-10]} {Dmel: FBgn0004647, N, Notch, [Score=50.1, Expect=4e-07]} {RNA1509_29817} {RNA1310_28236} {RNA815_11876.1} |
14. | MligTC455_27513 | 326 | 6.8 | Mlig455_027937 | Neo: - Age: logFC(26M/2M)=-0.593 |
MAP3K4 | 0.95 | 0.950 | - | - | - | - | - | Mlig455_027937 {REF} {Length: 2685} {Pfam: Protein kinase domain [PF00069.27, score=165.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=123.4]; Ankyrin repeats (3 copies) [PF12796.9, score=78.4]; Ankyrin repeats (many copies) [PF13637.8, score=58.3]; Ankyrin repeat [PF13606.8, score=56.2]; Ankyrin repeats (many copies) [PF13857.8, score=46.5]; Ankyrin repeat [PF00023.32, score=40.7]; Fungal protein kinase [PF17667.3, score=27.5]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=132, Expect=4e-31]} {Mouse: ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=6e-30]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=123, Expect=2e-28]; ENSMUSG00000031303, Map3k15, mitogen-activated protein kinase kinase kinase 15, [Score=122, Expect=3e-28]} {Dmel: FBgn0024329, Mekk1, [Score=126, Expect=2e-29]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=137, Expect=4e-33]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=112, Expect=2e-25]} {RNA1509_27731} {RNA1310_10050} {RNA815_9449.1} |
15. | MligTC455_28590 | 8 | 0.17 | Mlig455_036217 | Neo: - Age: - |
0.95 | - | - | - | 0.950 | - | - | Mlig455_036217 {REF} {Length: 55} {NoTransDecoderORF} {RNA1509_51858} | |
16. | MligTC455_51655 | 303 | 6.31 | Mlig455_015084, Mlig455_015200, Mlig455_027162 | Neo: - |
0.95 | - | - | - | 0.950 | - | - | Mlig455_015084 {REF} {Length: 746} {TRANSSPLICED} {RNA1310_65067} {RNA815_34678} Mlig455_015200 {REF} {Length: 788} {TRANSSPLICED} {RNA1310_65067} {RNA815_34678} Mlig455_027162 {REF} {Length: 788} {TRANSSPLICED} {RNA1310_65067} {RNA815_34678} |