Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_52020 | 2033 | 42.35 | Mlig455_066463 | Neo: - Age: - Region-enriched R3: 1.238/0.03405 |
COTL1 | Mlig455_066463 {REF} {Length: 3008} {Pfam: Cofilin/tropomyosin-type actin-binding protein [PF00241.22, score=57.6]} {Human: ENSG00000103187, COTL1, coactosin like F-actin binding protein 1, [Score=98.6, Expect=1e-25]} {Mouse: ENSMUSG00000031827, Cotl1, coactosin-like 1 (Dictyostelium), [Score=96.7, Expect=5e-25]} {Dmel: FBgn0030955, CG6891, [Score=104, Expect=3e-28]} {Smed: dd_Smed_v6_63_0_1, dd_Smed_v6_63_0_1, [Score=94.0, Expect=5e-24]} {RNA1509_39410} {RNA1310_28066} {RNA815_8557} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.479 | 5.653 | 0.05796 | 0.55647 | |
RegionR2 | -0.528 | 5.653 | 0.29155 | 0.67985 | |
RegionR3 | 1.238 | 5.653 | 0.00121 | 0.03405 | |
RegionR4 | 0.906 | 5.653 | 0.04408 | 0.17714 | |
RegionR5 | 0.76 | 5.653 | 0.04440 | 0.17195 | |
RegionR6 | 1.111 | 5.653 | 0.00402 | 0.09560 | |
RegionR7 | -0.655 | 5.653 | 0.15539 | 0.72832 | |
RegionR8 | -1.353 | 5.653 | 0.01719 | 0.25494 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.376 | 5.653 | 0.70149 | 1.00000 | |
RegenerationR2 | -0.894 | 5.653 | 0.08179 | 0.46054 | |
RegenerationR3 | -1.143 | 5.653 | 0.02456 | 0.28271 | |
RegenerationR4 | -0.683 | 5.653 | 0.19427 | 0.63918 | |
RegenerationR5 | -0.974 | 5.653 | 0.05543 | 0.37753 | |
RegenerationR6 | -1.249 | 5.653 | 0.01469 | 0.14932 | |
RegenerationBL | -2.11 | 5.653 | 0.00045 | 0.01311 | |
RegenerationTP | 0.291 | 5.653 | 0.59727 | 0.95924 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_52020 | 2033 | 42.35 | Mlig455_066463 | Neo: - Age: - Region-enriched R3: 1.238/0.03405 |
COTL1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_066463 {REF} {Length: 3008} {Pfam: Cofilin/tropomyosin-type actin-binding protein [PF00241.22, score=57.6]} {Human: ENSG00000103187, COTL1, coactosin like F-actin binding protein 1, [Score=98.6, Expect=1e-25]} {Mouse: ENSMUSG00000031827, Cotl1, coactosin-like 1 (Dictyostelium), [Score=96.7, Expect=5e-25]} {Dmel: FBgn0030955, CG6891, [Score=104, Expect=3e-28]} {Smed: dd_Smed_v6_63_0_1, dd_Smed_v6_63_0_1, [Score=94.0, Expect=5e-24]} {RNA1509_39410} {RNA1310_28066} {RNA815_8557} |
2. | MligTC455_42042 | 5653 | 117.77 | Mlig455_011072 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.324 Region-enriched R3: 1.823/0.00256 |
4.801 | 0.769 | 0.876 | 0.727 | 0.748 | 0.730 | 0.951 | Mlig455_011072 {REF} {Length: 901} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=22.3]; PRELI-like family [PF04707.16, score=19.8]} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1310_48326.1, RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378, RNA815_23354} | |
3. | MligTC455_52019 | 8734 | 181.96 | Mlig455_020071, Mlig455_040874 | Neo: - Age: - |
COTL1 | 3.769 | 0.962 | 0.944 | - | 0.962 | 0.901 | - | Mlig455_020071 {REF} {Length: 2539} {Pfam: Cofilin/tropomyosin-type actin-binding protein [PF00241.22, score=57.5]} {Human: ENSG00000103187, COTL1, coactosin like F-actin binding protein 1, [Score=98.6, Expect=2e-25]} {Mouse: ENSMUSG00000031827, Cotl1, coactosin-like 1 (Dictyostelium), [Score=96.7, Expect=5e-25]} {Dmel: FBgn0030955, CG6891, [Score=105, Expect=2e-28]} {Smed: dd_Smed_v6_63_0_1, dd_Smed_v6_63_0_1, [Score=94.4, Expect=4e-24]} {RNA1509_39410} {RNA1310_28066} {RNA815_15985} Mlig455_040874 {REF} {Length: 1036} {Pfam: Cofilin/tropomyosin-type actin-binding protein [PF00241.22, score=56.8]} {Human: ENSG00000103187, COTL1, coactosin like F-actin binding protein 1, [Score=97.4, Expect=5e-26]} {Mouse: ENSMUSG00000031827, Cotl1, coactosin-like 1 (Dictyostelium), [Score=95.9, Expect=2e-25]} {Dmel: FBgn0030955, CG6891, [Score=102, Expect=3e-28]} {Smed: dd_Smed_v6_63_0_1, dd_Smed_v6_63_0_1, [Score=92.8, Expect=2e-24]} {RNA1509_18981, RNA1509_39939, RNA1509_48173, RNA1509_6793} {RNA1310_1685.1, RNA1509_18981, RNA1509_39939, RNA1509_48173} {RNA1509_18981, RNA1509_39939, RNA1509_48173, RNA815_8557} |
4. | MligTC455_38724 | 5697 | 118.69 | Mlig455_045051 | Neo: - Age: logFC(26M/2M)=-0.423 Region-enriched R3: 1.948/0.00202 |
PANK4 | 3.397 | 0.821 | 0.886 | 0.737 | - | - | 0.953 | Mlig455_045051 {REF} {Length: 2009} {Pfam: Fumble [PF03630.16, score=127.5]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=102, Expect=2e-23]} {Dmel: FBgn0011205, fbl, fumble, [Score=86.7, Expect=1e-18]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=82.4, Expect=3e-17]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [RH, Score=225, Expect=1e-70]} {RNA1509_11373, RNA1509_768} {RNA1310_14353, RNA1509_11373} {RNA1509_11373, RNA815_1414} |
5. | MligTC455_17283 | 1601 | 33.35 | Mlig455_013088 | Neo: - Age: Down-Down-Up Region-enriched R4: 2.185/0.00000 |
1.683 | 0.721 | - | - | 0.962 | - | - | Mlig455_013088 {REF} {Length: 1152} {TRANSSPLICED} {Pfam: Methyltransferase small domain [PF05175.16, score=68.7]; Methyltransferase domain [PF08242.14, score=41.7]; Methyltransferase domain [PF13649.8, score=39.4]; Methyltransferase domain [PF13847.8, score=35.4]; Methyltransferase domain [PF08241.14, score=33.4]; Putative methyltransferase [PF02390.19, score=31.4]; Methyltransferase domain [PF12847.9, score=27.0]; RNA methyltransferase [PF05971.14, score=26.1]; Methyltransferase domain [PF13489.8, score=25.0]; Lysine methyltransferase [PF10294.11, score=24.5]; tRNA methyltransferase complex GCD14 subunit [PF08704.12, score=23.7]; RNA cap guanine-N2 methyltransferase [PF09445.12, score=23.4]; Conserved hypothetical protein 95 [PF03602.17, score=22.8]; Domain of unknown function (DUF2431) [PF10354.11, score=22.4]; Methyltransferase domain [PF13578.8, score=21.5]; tRNA (adenine(22)-N(1))-methyltransferase [PF04816.14, score=21.2]; Putative RNA methylase family UPF0020 [PF01170.20, score=19.8]; Ribosomal protein L11 methyltransferase (PrmA) [PF06325.15, score=19.7]} {RNA1509_4717} {RNA1310_20108} {RNA815_4785.1} | |
6. | MligTC455_37421 | 2101 | 43.77 | Mlig455_042713, Mlig455_042814 | Neo: - Age: - Region-enriched R5: 1.953/0.00000 |
0.963 | - | - | - | 0.963 | - | - | Mlig455_042713 {REF} {Length: 1861} {Pfam: Aminotransferase class-V [PF00266.21, score=59.9]; Aminotransferase class I and II [PF00155.23, score=31.5]} {Smed: dd_Smed_v6_6547_0_1, dd_Smed_v6_6547_0_1, [RH, Score=218, Expect=7e-67]} {RNA1509_29088} {RNA1310_17454, RNA1509_29088} {RNA1509_29088, RNA815_8720} Mlig455_042814 {REF} {Length: 1562} {Pfam: Aminotransferase class-V [PF00266.21, score=59.8]; Aminotransferase class I and II [PF00155.23, score=32.4]} {Dmel: FBgn0032393, CG12264, [Score=48.1, Expect=9e-06]} {Smed: dd_Smed_v6_6547_0_1, dd_Smed_v6_6547_0_1, [RH, Score=203, Expect=2e-61]} {RNA1509_19162, RNA1509_53034} {RNA1310_18376, RNA1509_19162, RNA1509_53034} {RNA1509_19162, RNA1509_53034, RNA815_8720} |
|
7. | MligTC455_36392 | 39001 | 812.51 | Mlig455_045127 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.250 Region-enriched R3: 1.703/0.00504 |
PROC | 0.957 | - | - | - | - | 0.957 | - | Mlig455_045127 {REF} {Length: 860} {Pfam: Trypsin [PF00089.28, score=97.2]; Trypsin-like peptidase domain [PF13365.8, score=38.2]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=66.2, Expect=4e-12]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=75.5, Expect=2e-15]; ENSMUSG00000034039, Prss29, protease, serine 29, [Score=73.6, Expect=4e-15]} {Dmel: FBgn0036738, CG7542, [Score=77.0, Expect=1e-16]} {Celegans: WBGene00006621, try-3, TRYpsin-like protease, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=112, Expect=2e-30]} {RNA1509_29, RNA1509_30952, RNA1509_45912} {RNA1310_47138.1, RNA1509_29, RNA1509_30952, RNA1509_45912} {RNA1509_29, RNA1509_30952, RNA1509_45912, RNA815_8541.1} |
8. | MligTC455_27994 | 6780 | 141.24 | Mlig455_046529, Mlig455_046656 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.627 Region-enriched R5: 1.394/0.00007 |
PPIA | 0.955 | - | - | - | 0.955 | - | - | Mlig455_046529 {REF} {Length: 1080} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=294.7]} {Human: ENSG00000196262, PPIA, peptidylprolyl isomerase A, [RH, Score=232, Expect=2e-76]} {Mouse: ENSMUSG00000071866, Ppia, peptidylprolyl isomerase A, [RH, Score=229, Expect=2e-75]} {Dmel: FBgn0004432, Cyp1, Cyclophilin 1, [Score=226, Expect=2e-73]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [RH, Score=251, Expect=3e-84]} {Smed: dd_Smed_v6_457_0_1, dd_Smed_v6_457_0_1, [RH, Score=237, Expect=4e-79]} {RNA1509_4222} {RNA1310_55233} {RNA815_27193} Mlig455_046656 {REF} {Length: 1071} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=268.9]} {Human: ENSG00000196262, PPIA, peptidylprolyl isomerase A, [RH, Score=235, Expect=9e-78]} {Mouse: ENSMUSG00000071866, Ppia, peptidylprolyl isomerase A, [RH, Score=234, Expect=1e-77]} {Dmel: FBgn0004432, Cyp1, Cyclophilin 1, [Score=229, Expect=8e-75]} {Celegans: WBGene00000879, cyn-3, Peptidyl-prolyl cis-trans isomerase 3, [RH, Score=251, Expect=3e-84]} {Smed: dd_Smed_v6_457_0_1, dd_Smed_v6_457_0_1, [RH, Score=241, Expect=1e-80]} {RNA1509_4222} {RNA1310_55233} {RNA815_27193} |
9. | MligTC455_44182 | 5080 | 105.83 | Mlig455_052125, Mlig455_054123 | Neo: - Age: - Regeneration-downregulated BL: -1.159 Regeneration-depleted BL: -1.159 |
RAB5B | 0.954 | - | - | - | - | 0.954 | - | Mlig455_052125 {REF} {Length: 3077} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=199.2]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=120.1]; ADP-ribosylation factor family [PF00025.23, score=49.2]; 50S ribosome-binding GTPase [PF01926.25, score=25.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.2]; RsgA GTPase [PF03193.18, score=22.0]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=276, Expect=2e-94]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=274, Expect=3e-93]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=272, Expect=4e-93]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=276, Expect=1e-94]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=273, Expect=2e-93]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=272, Expect=3e-93]} {Dmel: FBgn0014010, Rab5, [RH, Score=271, Expect=5e-93]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=265, Expect=7e-91]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=276, Expect=3e-95]} {RNA1509_11276, RNA1509_29926, RNA1509_4956} {RNA1310_20168.2, RNA1509_11276, RNA1509_29926, RNA1509_4956} {RNA1509_11276, RNA1509_29926, RNA1509_4956, RNA815_13866} Mlig455_054123 {REF} {Length: 2395} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=199.2]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=120.1]; ADP-ribosylation factor family [PF00025.23, score=49.2]; 50S ribosome-binding GTPase [PF01926.25, score=25.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.2]; RsgA GTPase [PF03193.18, score=22.0]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=276, Expect=2e-94]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=274, Expect=3e-93]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=272, Expect=4e-93]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=276, Expect=1e-94]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=273, Expect=2e-93]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=272, Expect=3e-93]} {Dmel: FBgn0014010, Rab5, [RH, Score=271, Expect=5e-93]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=265, Expect=7e-91]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=276, Expect=3e-95]} {RNA1509_15436, RNA1509_26235, RNA1509_38165, RNA1509_4956} {RNA1310_20168.2, RNA1509_15436, RNA1509_26235, RNA1509_38165} {RNA1509_15436, RNA1509_26235, RNA1509_38165, RNA815_13866} |
10. | MligTC455_35812 | 912 | 18.99 | Mlig455_063433, Mlig455_063463 | Neo: - Age: - Region-enriched R6: 2.260/0.00346 |
ARHGAP45 | 0.953 | - | - | - | - | 0.953 | - | Mlig455_063433 {REF} {Length: 5901} {Pfam: RhoGAP domain [PF00620.29, score=137.5]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=27.8]} {Human: ENSG00000180448, ARHGAP45, Rho GTPase activating protein 45, [Score=104, Expect=5e-22]; ENSG00000089639, GMIP, GEM interacting protein, [Score=102, Expect=4e-21]} {Mouse: ENSMUSG00000035697, Arhgap45, Rho GTPase activating protein 45, [Score=106, Expect=9e-23]; ENSMUSG00000036246, Gmip, Gem-interacting protein, [Score=105, Expect=2e-22]} {Dmel: FBgn0030685, Graf, GTPase regulator associated with FAK, [Score=92.8, Expect=1e-18]} {Celegans: WBGene00015418, pac-1, GTPase-activating protein pac-1, [Score=91.7, Expect=1e-18]} {Smed: dd_Smed_v6_5208_0_2, dd_Smed_v6_5208_0_2, [RH, Score=143, Expect=8e-35]} {RNA1509_10752, RNA1509_23661, RNA1509_48362} {RNA1310_5626, RNA1509_10752, RNA1509_23661, RNA1509_48362} {RNA1509_10752, RNA1509_23661, RNA1509_48362, RNA815_3834} Mlig455_063463 {REF} {Length: 4819} {Pfam: RhoGAP domain [PF00620.29, score=135.2]} {Human: ENSG00000180448, ARHGAP45, Rho GTPase activating protein 45, [Score=107, Expect=5e-23]} {Mouse: ENSMUSG00000035697, Arhgap45, Rho GTPase activating protein 45, [Score=106, Expect=6e-23]; ENSMUSG00000036246, Gmip, Gem-interacting protein, [Score=101, Expect=2e-21]} {Dmel: FBgn0030685, Graf, GTPase regulator associated with FAK, [Score=89.7, Expect=7e-18]} {Celegans: WBGene00015418, pac-1, GTPase-activating protein pac-1, [Score=89.0, Expect=8e-18]} {Smed: dd_Smed_v6_5208_0_2, dd_Smed_v6_5208_0_2, [RH, Score=142, Expect=1e-34]} {RNA1509_48362} {RNA1310_5626} {RNA815_3834} |
11. | MligTC455_17515 | 227 | 4.73 | Mlig455_021122 | Neo: - Age: Down-Up-Down |
0.952 | - | - | - | 0.952 | - | - | Mlig455_021122 {REF} {Length: 1268} {TRANSSPLICED} {RNA1509_17603} {RNA1310_24433} {RNA815_20109} | |
12. | MligTC455_35632 | 6861 | 142.93 | Mlig455_047206 | Neo: - Age: - Region-enriched R3: 1.984/0.00032 |
DHDH | 0.951 | - | - | - | - | - | 0.951 | Mlig455_047206 {REF} {Length: 1483} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=86.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=245, Expect=8e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=247, Expect=1e-79]} {Dmel: FBgn0031418, CG3609, [Score=229, Expect=5e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=211, Expect=2e-66]} {RNA1509_4889} {RNA1310_24236} {RNA815_11111.1} |
13. | MligTC455_51283 | 194 | 4.04 | Mlig455_016832 | Neo: Int S/G2/M Age: - Region-enriched R5: 3.547/0.00000 |
0.951 | - | - | - | 0.951 | - | - | Mlig455_016832 {REF} {Length: 988} {TRANSSPLICED} {Pfam: Predicted integral membrane zinc-ribbon metal-binding protein [PF10058.11, score=39.1]} {Smed: dd_Smed_v6_6045_0_1, dd_Smed_v6_6045_0_1, [Score=45.4, Expect=1e-05]} {RNA1310_42430} {RNA815_29475} | |
14. | MligTC455_28583 | 1530 | 31.88 | Mlig455_069282 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.324 |
FKBP8 | 0.95 | - | - | - | 0.950 | - | - | Mlig455_069282 {REF} {Length: 2937} {TRANSSPLICED} {Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase [PF00254.30, score=36.8]; Tetratricopeptide repeat [PF00515.30, score=32.4]; Tetratricopeptide repeat [PF07719.19, score=26.5]; Tetratricopeptide repeat [PF13181.8, score=19.3]} {Human: ENSG00000105701, FKBP8, FK506 binding protein 8, [Score=143, Expect=2e-36]} {Mouse: ENSMUSG00000019428, Fkbp8, FK506 binding protein 8, [Score=139, Expect=3e-35]} {Dmel: FBgn0034368, CG5482, [RH, Score=182, Expect=8e-51]} {Celegans: WBGene00001431, fkb-6, Peptidylprolyl isomerase, [Score=67.0, Expect=2e-11]} {Smed: dd_Smed_v6_1474_0_1, dd_Smed_v6_1474_0_1, [Score=159, Expect=1e-41]} {RNA1509_26580} {RNA1310_10924.2} {RNA815_2056.1} |