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Results for MligTC455_53088

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53088 804 16.74 Mlig455_054521, Mlig455_055377, Mlig455_055451

Neo: -

Age: -

TPRG1L

Mlig455_054521 {REF} {Length: 1274} {TRANSSPLICED} {Pfam: Inositol phosphatase [PF12456.10, score=32.3]} {Human: ENSG00000158109, TPRG1L, tumor protein p63 regulated 1 like, [Score=62.8, Expect=3e-11]} {Mouse: ENSMUSG00000029030, Tprgl, transformation related protein 63 regulated like, [Score=65.9, Expect=1e-12]} {Smed: dd_Smed_v6_2044_0_1, dd_Smed_v6_2044_0_1, [Score=56.2, Expect=1e-09]} {RNA1509_7979} {RNA1310_8605} {RNA815_10846}

Mlig455_055377 {REF} {Length: 1261} {Pfam: Inositol phosphatase [PF12456.10, score=32.4]} {Human: ENSG00000158109, TPRG1L, tumor protein p63 regulated 1 like, [Score=61.2, Expect=8e-11]} {Mouse: ENSMUSG00000029030, Tprgl, transformation related protein 63 regulated like, [Score=63.9, Expect=6e-12]} {RNA1509_7979} {RNA1310_8605} {RNA815_10846}

Mlig455_055451 {REF} {Length: 1330} {TRANSSPLICED} {Pfam: Inositol phosphatase [PF12456.10, score=31.9]} {Human: ENSG00000158109, TPRG1L, tumor protein p63 regulated 1 like, [Score=68.9, Expect=2e-13]} {Mouse: ENSMUSG00000029030, Tprgl, transformation related protein 63 regulated like, [Score=71.2, Expect=2e-14]} {Smed: dd_Smed_v6_2044_0_1, dd_Smed_v6_2044_0_1, [Score=57.0, Expect=9e-10]} {RNA1509_40030} {RNA1310_8605} {RNA815_10846}

Cumulative graph for MligTC455_53088

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.986 4.476 0.43214 1.00000
RegionR2 -0.83 4.476 0.23258 0.60499
RegionR3 1.27 4.476 0.00862 0.13849
RegionR4 1.243 4.476 0.04137 0.16937
RegionR5 0.453 4.476 0.33573 0.68169
RegionR6 0.592 4.476 0.25718 0.84342
RegionR7 -2.496 4.476 0.00708 0.13871
RegionR8 -1.22 4.476 0.24197 0.85887

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.535 4.476 0.73090 1.00000
RegenerationR2 0.163 4.476 0.77948 0.98312
RegenerationR3 0.2 4.476 0.73341 0.95887
RegenerationR4 0.212 4.476 0.73755 0.96688
RegenerationR5 1.231 4.476 0.03422 0.30789
RegenerationR6 0.073 4.476 0.90422 1.00000
RegenerationBL 0.975 4.476 0.19118 0.52535
RegenerationTP 1.257 4.476 0.17666 0.61081


Genes with expression patterns similar to MligTC455_53088

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53088 804 16.74 Mlig455_054521, Mlig455_055377, Mlig455_055451

Neo: -

Age: -

TPRG1L 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_054521 {REF} {Length: 1274} {TRANSSPLICED} {Pfam: Inositol phosphatase [PF12456.10, score=32.3]} {Human: ENSG00000158109, TPRG1L, tumor protein p63 regulated 1 like, [Score=62.8, Expect=3e-11]} {Mouse: ENSMUSG00000029030, Tprgl, transformation related protein 63 regulated like, [Score=65.9, Expect=1e-12]} {Smed: dd_Smed_v6_2044_0_1, dd_Smed_v6_2044_0_1, [Score=56.2, Expect=1e-09]} {RNA1509_7979} {RNA1310_8605} {RNA815_10846}

Mlig455_055377 {REF} {Length: 1261} {Pfam: Inositol phosphatase [PF12456.10, score=32.4]} {Human: ENSG00000158109, TPRG1L, tumor protein p63 regulated 1 like, [Score=61.2, Expect=8e-11]} {Mouse: ENSMUSG00000029030, Tprgl, transformation related protein 63 regulated like, [Score=63.9, Expect=6e-12]} {RNA1509_7979} {RNA1310_8605} {RNA815_10846}

Mlig455_055451 {REF} {Length: 1330} {TRANSSPLICED} {Pfam: Inositol phosphatase [PF12456.10, score=31.9]} {Human: ENSG00000158109, TPRG1L, tumor protein p63 regulated 1 like, [Score=68.9, Expect=2e-13]} {Mouse: ENSMUSG00000029030, Tprgl, transformation related protein 63 regulated like, [Score=71.2, Expect=2e-14]} {Smed: dd_Smed_v6_2044_0_1, dd_Smed_v6_2044_0_1, [Score=57.0, Expect=9e-10]} {RNA1509_40030} {RNA1310_8605} {RNA815_10846}
2. MligTC455_16023 622 12.96 Mlig455_048417, Mlig455_049055

Neo: -

Age: logFC(26M/2M)=-0.353

Region-enriched R4: 1.900/0.00082
Region-enriched R3: 1.176/0.03983

SLC10A3, SLC10A6 3.372 - 0.771 - 0.786 0.854 0.961

Mlig455_048417 {REF} {Length: 2016} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=43.0]} {Human: ENSG00000145283, SLC10A6, solute carrier family 10 member 6, [Score=60.8, Expect=1e-09]; ENSG00000126903, SLC10A3, solute carrier family 10 member 3, [Score=60.5, Expect=2e-09]} {Mouse: ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=59.7, Expect=2e-09]} {Dmel: FBgn0030638, CG11655, [Score=79.3, Expect=7e-16]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=92.8, Expect=2e-20]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [Score=89.4, Expect=2e-19]} {RNA1509_13359} {RNA1310_13071} {RNA815_4905}

Mlig455_049055 {REF} {Length: 2118} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=94.9]} {Human: ENSG00000126903, SLC10A3, solute carrier family 10 member 3, [RH, Score=130, Expect=3e-32]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=4e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=127, Expect=3e-32]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=2e-30]} {Dmel: FBgn0030638, CG11655, [RH, Score=191, Expect=2e-54]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=221, Expect=4e-65]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [Score=229, Expect=4e-69]} {RNA1509_13359, RNA1509_35282} {RNA1310_13071, RNA1509_13359, RNA1509_35282} {RNA1509_13359, RNA1509_35282, RNA815_4905}
3. MligTC455_16022 616 12.83 Mlig455_048556

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.801/0.00244
Region-enriched R3: 1.214/0.03772

SLC10A3 3.294 - 0.766 - 0.730 0.844 0.954 Mlig455_048556 {REF} {Length: 1530} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=56.7]} {Human: ENSG00000126903, SLC10A3, solute carrier family 10 member 3, [Score=95.5, Expect=6e-21]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [Score=92.0, Expect=5e-20]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0030638, CG11655, [Score=141, Expect=2e-37]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=161, Expect=2e-44]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [Score=161, Expect=5e-45]} {RNA1509_13359} {RNA1310_13071} {RNA815_4905}
4. MligTC455_32587 347 7.22 Mlig455_002565, Mlig455_011377, Mlig455_056647

Neo: -

Age: logFC(26M/2M)=-0.638

Region-enriched R4: 5.751/0.00210
Region-enriched R5: 3.262/0.03233

SLC17A5 2.661 - - - 0.836 0.850 0.975

Mlig455_002565 {REF} {Length: 2259} {Pfam: hAT family C-terminal dimerisation region [PF05699.16, score=32.3]} {Smed: dd_Smed_v6_17002_0_4, dd_Smed_v6_17002_0_4, [Score=77.0, Expect=1e-14]} {RNA1509_58448} {RNA1310_63461} {RNA815_51469}

Mlig455_011377 {REF} {Length: 3512} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=183.3]} {Human: ENSG00000119899, SLC17A5, solute carrier family 17 member 5, [RH, Score=363, Expect=6e-120]} {Mouse: ENSMUSG00000049624, Slc17a5, solute carrier family 17 (anion/sugar transporter), member 5, [RH, Score=365, Expect=6e-121]} {Dmel: FBgn0024315, Picot, [RH, Score=324, Expect=1e-104]} {Celegans: WBGene00008000, slc-17.2, Uncharacterized transporter slc-17.2, [RH, Score=324, Expect=3e-105]} {Smed: dd_Smed_v6_4910_0_1, dd_Smed_v6_4910_0_1, [RH, Score=384, Expect=9e-129]} {RNA1509_50557} {RNA1310_9071} {RNA815_18641}

Mlig455_056647 {REF} {Length: 2390} {Pfam: hAT family C-terminal dimerisation region [PF05699.16, score=32.2]} {Smed: dd_Smed_v6_17002_0_4, dd_Smed_v6_17002_0_4, [Score=91.7, Expect=4e-19]} {RNA1509_58448} {RNA1310_82811} {RNA815_51469}
5. MligTC455_37180 372 7.75 Mlig455_020649

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.893/0.00005
Region-enriched R5: 1.749/0.04568

SAXO2 2.582 - 0.803 - 0.818 - 0.961 Mlig455_020649 {REF} {Length: 3369} {Human: ENSG00000188659, SAXO2, stabilizer of axonemal microtubules 2, [Score=56.6, Expect=3e-08]} {Mouse: ENSMUSG00000038570, Saxo2, stabilizer of axonemal microtubules 2, [Score=62.8, Expect=2e-10]} {Smed: dd_Smed_v6_12892_0_1, dd_Smed_v6_12892_0_1, [Score=48.1, Expect=5e-06]} {RNA1509_27202, RNA1509_41936} {RNA1310_7566, RNA1509_41936} {RNA1509_41936, RNA815_9731}
6. MligTC455_43800 4639 96.64 Mlig455_041018, Mlig455_041127, Mlig455_041183

Neo: -

Age: -

RGN 2.54 - - - 0.805 0.769 0.966

Mlig455_041018 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=221.4]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=187, Expect=4e-57]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=190, Expect=3e-58]} {Dmel: FBgn0030362, regucalcin, [Score=142, Expect=6e-40]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=5e-53]} {RNA1509_3252} {RNA1310_20018.1} {RNA815_8819.1}

Mlig455_041127 {REF} {Length: 1500} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=181, Expect=1e-54]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=184, Expect=3e-56]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=3e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=178, Expect=8e-54]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}

Mlig455_041183 {REF} {Length: 1502} {TRANSSPLICED} {Pfam: SMP-30/Gluconolactonase/LRE-like region [PF08450.14, score=216.7]; Two component regulator propeller [PF07494.13, score=22.9]} {Human: ENSG00000130988, RGN, regucalcin, [RH, Score=182, Expect=5e-55]} {Mouse: ENSMUSG00000023070, Rgn, regucalcin, [RH, Score=186, Expect=9e-57]} {Dmel: FBgn0038257, smp-30, Senescence marker protein-30, [Score=145, Expect=4e-41]} {Smed: dd_Smed_v6_3808_0_1, dd_Smed_v6_3808_0_1, [RH, Score=176, Expect=3e-53]} {RNA1509_3252} {RNA1310_7497.1} {RNA815_8819.1}
7. MligTC455_22151 1286 26.78 Mlig455_054961

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.174/0.00000
Region-enriched R3: 1.898/0.00000
Region-enriched R5: 1.123/0.00549

XDH 2.523 - - - 0.757 0.815 0.951 Mlig455_054961 {REF} {Length: 8931} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=746.5]; [2Fe-2S] binding domain [PF01799.22, score=187.9]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=151.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=115.0]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=110.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=28.4]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=490, Expect=1e-144]; ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=472, Expect=2e-138]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=496, Expect=5e-147]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=472, Expect=7e-139]} {Dmel: FBgn0038349, AOX3, Aldehyde oxidase 3, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=501, Expect=1e-148]} {RNA1509_48253} {RNA1310_3150.1} {RNA815_224.3}
8. MligTC455_40926 680 14.16 Mlig455_029450, Mlig455_029472

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.535/0.00634
Region-enriched R3: 2.023/0.02088

OTOF 2.517 - - - 0.753 0.806 0.958

Mlig455_029450 {REF} {Length: 7011} {Pfam: C2 domain [PF00168.32, score=238.1]; Ferlin C-terminus [PF16165.7, score=107.1]; FerB (NUC096) domain [PF08150.14, score=73.3]; FerI (NUC094) domain [PF08151.14, score=62.3]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=847, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=845, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [RH, Score=324, Expect=3e-89]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=145, Expect=3e-34]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1229, Expect=0.0]} {RNA1509_44062, RNA1509_58476} {RNA1310_427.1, RNA1509_44062} {RNA1509_44062, RNA815_1463}

Mlig455_029472 {REF} {Length: 6996} {Pfam: C2 domain [PF00168.32, score=238.4]; Ferlin C-terminus [PF16165.7, score=107.1]; FerB (NUC096) domain [PF08150.14, score=73.4]; FerI (NUC094) domain [PF08151.14, score=62.3]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=849, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=846, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [RH, Score=324, Expect=3e-89]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=145, Expect=3e-34]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1231, Expect=0.0]} {RNA1509_58476} {RNA1310_427.1, RNA1509_58476} {RNA1509_58476, RNA815_1463}
9. MligTC455_23027 1424 29.67 Mlig455_037516

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.237

Region-enriched R5: 1.343/0.00006
Region-enriched R4: 1.073/0.02114

DHRS4 2.5 0.951 - - 0.724 0.825 - Mlig455_037516 {REF} {Length: 4706} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=169.5]; short chain dehydrogenase [PF00106.27, score=111.5]; DDE superfamily endonuclease [PF03184.21, score=40.1]; OTU-like cysteine protease [PF02338.21, score=34.5]} {Human: ENSG00000284807, DHRS4, dehydrogenase/reductase 4, [Score=184, Expect=1e-51]; ENSG00000157326, DHRS4, dehydrogenase/reductase 4, [Score=184, Expect=1e-51]} {Mouse: ENSMUSG00000022210, Dhrs4, dehydrogenase/reductase (SDR family) member 4, [Score=179, Expect=4e-50]} {Dmel: FBgn0035588, CG10672, [Score=200, Expect=5e-57]} {Celegans: WBGene00000976, dhs-13, DeHydrogenases, Short chain, [Score=181, Expect=2e-51]} {Smed: dd_Smed_v6_6646_0_1, dd_Smed_v6_6646_0_1, [Score=190, Expect=2e-54]} {RNA1509_8082} {RNA1310_32758.3} {RNA815_14440.1}
10. MligTC455_41503 3372 70.25 Mlig455_015421

Neo: -

Age: -

Region-enriched R3: 1.663/0.00123

2.493 - - - 0.729 0.812 0.952 Mlig455_015421 {REF} {Length: 3377} {Pfam: Fasciclin domain [PF02469.24, score=41.0]} {Dmel: FBgn0032638, SPH93, Serine protease homolog 93, [Score=61.6, Expect=2e-09]} {RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1310_8987, RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1509_26815, RNA1509_27548, RNA1509_56488, RNA815_3084.1}
11. MligTC455_48796 3932 81.93 Mlig455_010032, Mlig455_063287

Neo: -

Age: -

Region-enriched R3: 1.371/0.00023

2.478 - - - 0.789 0.737 0.952

Mlig455_010032 {REF} {Length: 3305} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=3e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=727, Expect=0.0]} {RNA1509_1610, RNA1509_26475} {RNA1310_2842, RNA1509_1610, RNA1509_26475} {RNA1509_1610, RNA1509_26475, RNA815_1220.1}

Mlig455_063287 {REF} {Length: 3306} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=4e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1610} {RNA1310_2842} {RNA815_1220.1}
12. MligTC455_50449 2354 49.04 Mlig455_064469

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.266

Region-enriched R3: 1.639/0.00084
Region-enriched R5: 1.149/0.01827

KREMEN1 2.476 - - - 0.954 0.763 0.759 Mlig455_064469 {REF} {Length: 719} {TRANSSPLICED} {Pfam: WSC domain [PF01822.21, score=61.7]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=52.4, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=50.8, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=1e-08]} {RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774, RNA1509_51348} {RNA1310_56240.1, RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774} {RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774, RNA815_26405}
13. MligTC455_19214 797 16.61 Mlig455_067480, Mlig455_067488

Neo: -

Age: logFC(26M/2M)=0.411

Region-enriched R4: 2.048/0.00458

HSD11B1 2.462 - - - 0.722 0.772 0.968

Mlig455_067480 {REF} {Length: 1095} {Pfam: short chain dehydrogenase [PF00106.27, score=63.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=42.8]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=83.6, Expect=1e-18]} {Mouse: ENSMUSG00000029311, Hsd17b11, hydroxysteroid (17-beta) dehydrogenase 11, [Score=59.7, Expect=2e-10]} {Dmel: FBgn0039043, CG17121, [Score=49.7, Expect=7e-07]} {RNA1509_28182} {RNA1310_27439} {RNA815_13316}

Mlig455_067488 {REF} {Length: 1390} {Pfam: short chain dehydrogenase [PF00106.27, score=128.2]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.0]; KR domain [PF08659.12, score=25.0]; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [PF02882.21, score=18.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=158, Expect=4e-46]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=80.9, Expect=2e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=71.6, Expect=2e-14]} {RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1310_27439, RNA1509_28182, RNA1509_29712, RNA1509_41682} {RNA1509_28182, RNA1509_29712, RNA1509_41682, RNA815_13316}
14. MligTC455_35963 222 4.63 Mlig455_022679

Neo: -

Age: logFC(26M/2M)=0.351

Region-enriched R3: 1.680/0.02750

1.826 - - - 0.869 - 0.957 Mlig455_022679 {REF} {Length: 3869} {TRANSSPLICED} {Pfam: Glycosyl hydrolase family 63 C-terminal domain [PF03200.18, score=26.0]; Protein of unknown function (DUF4232) [PF14016.8, score=20.8]} {RNA1509_18909, RNA1509_19906, RNA1509_9146} {RNA1310_4028.1, RNA1509_18909, RNA1509_19906, RNA1509_9146} {RNA1509_18909, RNA1509_19906, RNA1509_9146, RNA815_1420}
15. MligTC455_15896 224 4.67 Mlig455_000871

Neo: -

Age: -

Region-enriched R3: 3.079/0.00082

SLC22A5 1.785 - - - 0.833 - 0.952 Mlig455_000871 {REF} {Length: 3053} {Pfam: Sugar (and other) transporter [PF00083.26, score=128.9]; Major Facilitator Superfamily [PF07690.18, score=82.2]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=191, Expect=3e-53]; ENSG00000172940, SLC22A13, solute carrier family 22 member 13, [Score=187, Expect=6e-52]} {Mouse: ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [Score=188, Expect=2e-52]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=187, Expect=5e-52]; ENSMUSG00000018900, Slc22a5, solute carrier family 22 (organic cation transporter), member 5, [Score=182, Expect=3e-50]} {Dmel: FBgn0086365, Orct2, Organic cation transporter 2, [Score=238, Expect=6e-71]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=183, Expect=6e-51]} {Smed: dd_Smed_v6_10903_0_1, dd_Smed_v6_10903_0_1, [RH, Score=244, Expect=2e-74]} {RNA1509_34392, RNA1509_36858, RNA1509_7569} {RNA1310_6516, RNA1509_34392, RNA1509_36858, RNA1509_7569} {RNA1509_34392, RNA1509_36858, RNA1509_7569, RNA815_4307.1}
16. MligTC455_07568 59 1.24 Mlig455_050176

Neo: -

Age: -

Region-enriched R4: 5.685/0.01793

1.782 - - - - 0.823 0.959 Mlig455_050176 {REF} {Length: 797} {RNA1509_50562} {RNA1310_122277}
17. MligTC455_35962 331 6.9 Mlig455_022661

Neo: -

Age: -

1.776 - - - 0.820 - 0.956 Mlig455_022661 {REF} {Length: 220} {NoTransDecoderORF} {RNA1509_19906} {RNA1310_19437} {RNA815_21043}
18. MligTC455_53528 378 7.87 Mlig455_040364

Neo: -

Age: logFC(26M/2M)=0.734

Region-enriched R4: 3.457/0.00234
Region-enriched R3: 2.972/0.00183

1.768 - - - 0.799 - 0.969 Mlig455_040364 {REF} {Length: 1576} {TRANSSPLICED} {Pfam: Universal stress protein family [PF00582.28, score=97.2]} {Smed: dd_Smed_v6_985_0_1, dd_Smed_v6_985_0_1, [RH, Score=119, Expect=9e-35]} {RNA1509_7232} {RNA1310_49135, RNA1509_7232} {RNA1509_7232, RNA815_18182.1}
19. MligTC455_50210 260 5.41 Mlig455_036928

Neo: -

Age: logFC(26M/2M)=1.112

1.751 - - - 0.801 - 0.950 Mlig455_036928 {REF} {Length: 2037} {TRANSSPLICED} {Pfam: Inosine-uridine preferring nucleoside hydrolase [PF01156.21, score=67.1]} {Dmel: FBgn0030511, CG11158, [Score=41.2, Expect=1e-05]} {Celegans: WBGene00017436, F13H8.3, [Score=51.2, Expect=3e-09]} {RNA1509_60162} {RNA1310_24900} {RNA815_15172}
20. MligTC455_53923 413 8.6 Mlig455_031505

Neo: -

Age: -

Region-enriched R3: 2.700/0.00511

MGAM 1.737 - - - - 0.765 0.972 Mlig455_031505 {REF} {Length: 3805} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=338.5]} {Human: ENSG00000282607, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000090402, SI, sucrase-isomaltase, [Score=359, Expect=6e-109]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]; ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=361, Expect=6e-112]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=353, Expect=4e-107]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=150, Expect=6e-38]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [Score=364, Expect=3e-115]} {Smed: dd_Smed_v6_4668_0_1, dd_Smed_v6_4668_0_1, [Score=333, Expect=6e-104]} {RNA1509_3169} {RNA1310_1135} {RNA815_4014}
21. MligTC455_40821 347 7.22 Mlig455_016792

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.666

1.724 - - - - 0.773 0.951 Mlig455_016792 {REF} {Length: 1267} {TRANSSPLICED} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=48.2]; short chain dehydrogenase [PF00106.27, score=38.4]} {Dmel: FBgn0030968, CG7322, [Score=52.4, Expect=3e-08]} {Celegans: WBGene00000984, dhs-21, L-xylulose reductase, [Score=51.6, Expect=4e-08]} {RNA1509_44109} {RNA1310_24446.1} {RNA815_13838}
22. MligTC455_53873 315 6.57 Mlig455_031286

Neo: -

Age: Down-Down-Up

Region-enriched R5: 2.452/0.00042
Region-enriched R4: 2.381/0.02290

TPMT 1.693 - 0.733 - 0.960 - - Mlig455_031286 {REF} {Length: 1329} {TRANSSPLICED} {Pfam: Thiopurine S-methyltransferase (TPMT) [PF05724.13, score=127.5]} {Human: ENSG00000137364, TPMT, thiopurine S-methyltransferase, [RH, Score=94.7, Expect=6e-23]} {Mouse: ENSMUSG00000021376, Tpmt, thiopurine methyltransferase, [RH, Score=90.9, Expect=1e-21]} {Smed: dd_Smed_v6_21433_0_1, dd_Smed_v6_21433_0_1, [RH, Score=90.1, Expect=7e-22]} {RNA1509_48062} {RNA1310_27111.1} {RNA815_28412}
23. MligTC455_39889 2060 42.92 Mlig455_033747

Neo: -

Age: -

GDPD1 1.682 - - - 0.729 - 0.953 Mlig455_033747 {REF} {Length: 1632} {Pfam: Glycerophosphoryl diester phosphodiesterase family [PF03009.19, score=130.1]} {Human: ENSG00000153982, GDPD1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=57.4, Expect=4e-09]} {Mouse: ENSMUSG00000061666, Gdpd1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=55.1, Expect=4e-08]} {Celegans: WBGene00021497, Y40C5A.4, [RH, Score=53.9, Expect=5e-08]} {RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1310_11037, RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1509_4963, RNA1509_55034, RNA1509_9150, RNA815_4734}
24. MligTC455_35287 454 9.45 Mlig455_025493, Mlig455_070516

Neo: -

Age: -

Region-enriched R4: 2.155/0.03256
Region-enriched R3: 2.113/0.04928

PDE11A, PDE5A 1.677 - 0.714 - - - 0.963

Mlig455_025493 {REF} {Length: 3767} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=131.1]; GAF domain [PF13492.8, score=22.4]} {Human: ENSG00000128655, PDE11A, phosphodiesterase 11A, [Score=326, Expect=1e-104]; ENSG00000284741, PDE11A, phosphodiesterase 11A, [Score=326, Expect=2e-103]; ENSG00000138735, PDE5A, phosphodiesterase 5A, [Score=313, Expect=4e-97]} {Mouse: ENSMUSG00000075270, Pde11a, phosphodiesterase 11A, [Score=323, Expect=4e-100]} {Dmel: FBgn0085370, Pde11, Phosphodiesterase 11, [Score=334, Expect=3e-103]} {Celegans: WBGene00016328, pde-5, Probable 3',5'-cyclic phosphodiesterase pde-5, [Score=219, Expect=4e-63]} {Smed: dd_Smed_v6_8595_0_4, dd_Smed_v6_8595_0_4, [Score=367, Expect=3e-117]} {RNA1509_11890} {RNA1310_3423.1} {RNA815_991}

Mlig455_070516 {REF} {Length: 5806} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=231.4]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=137.2]; GAF domain [PF01590.28, score=102.2]; GAF domain [PF13185.8, score=56.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=33.2]; GAF domain [PF13492.8, score=25.3]} {Human: ENSG00000138735, PDE5A, phosphodiesterase 5A, [RH, Score=625, Expect=0.0]; ENSG00000128655, PDE11A, phosphodiesterase 11A, [RH, Score=608, Expect=0.0]} {Mouse: ENSMUSG00000053965, Pde5a, phosphodiesterase 5A, cGMP-specific, [RH, Score=621, Expect=0.0]; ENSMUSG00000075270, Pde11a, phosphodiesterase 11A, [RH, Score=617, Expect=0.0]} {Dmel: FBgn0085370, Pde11, Phosphodiesterase 11, [RH, Score=642, Expect=0.0]} {Celegans: WBGene00016328, pde-5, Probable 3',5'-cyclic phosphodiesterase pde-5, [Score=304, Expect=3e-88]} {Smed: dd_Smed_v6_8595_0_4, dd_Smed_v6_8595_0_4, [RH, Score=680, Expect=0.0]} {RNA1509_11890} {RNA1310_3423.1} {RNA815_991}
25. MligTC455_23013 590 12.28 Mlig455_014573

Neo: -

Age: -

Region-enriched R3: 1.767/0.00535
Region-enriched R5: 1.415/0.01021

DMGDH 1.66 - - - - 0.701 0.959 Mlig455_014573 {REF} {Length: 4164} {Pfam: Aminomethyltransferase folate-binding domain [PF01571.23, score=214.0]; FAD dependent oxidoreductase [PF01266.26, score=201.5]; Glycine cleavage T-protein C-terminal barrel domain [PF08669.13, score=64.7]; FAD dependent oxidoreductase central domain [PF16350.7, score=55.7]; FAD binding domain [PF01494.21, score=36.2]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=28.6]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=26.9]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=26.5]; FAD binding domain [PF00890.26, score=23.9]; Thi4 family [PF01946.19, score=20.8]; FAD dependent oxidoreductase [PF12831.9, score=18.9]} {Human: ENSG00000132837, DMGDH, dimethylglycine dehydrogenase, [RH, Score=947, Expect=0.0]} {Mouse: ENSMUSG00000042102, Dmgdh, dimethylglycine dehydrogenase precursor, [RH, Score=949, Expect=0.0]} {Dmel: FBgn0034276, Sardh, Sarcosine dehydrogenase, [Score=321, Expect=1e-95]} {Celegans: WBGene00021355, Y37E3.17, [RH, Score=450, Expect=3e-145]} {Smed: dd_Smed_v6_4377_0_3, dd_Smed_v6_4377_0_3, [RH, Score=921, Expect=0.0]} {RNA1509_18378, RNA1509_22900, RNA1509_29343, RNA1509_44138, RNA1509_55845} {RNA1310_3038.1, RNA1509_18378, RNA1509_22900, RNA1509_29343, RNA1509_44138, RNA1509_55845} {RNA1509_18378, RNA1509_22900, RNA1509_29343, RNA1509_44138, RNA1509_55845, RNA815_868.1}
26. MligTC455_30399 167 3.48 Mlig455_070660

Neo: -

Age: Down-Down-Up

Region-enriched R4: 4.847/0.00001

TRAF6 0.97 - - - - - 0.970 Mlig455_070660 {REF} {Length: 2276} {Pfam: TRAF-type zinc finger [PF02176.20, score=39.6]; Laminin Domain II [PF06009.14, score=18.8]} {Human: ENSG00000175104, TRAF6, TNF receptor associated factor 6, [Score=94.4, Expect=1e-19]} {Mouse: ENSMUSG00000027164, Traf6, TNF receptor-associated factor 6, [Score=92.8, Expect=2e-19]; ENSMUSG00000026942, Traf2, TNF receptor-associated factor 2, [Score=89.7, Expect=2e-18]; ENSMUSG00000021277, Traf3, TNF receptor-associated factor 3, [Score=88.6, Expect=6e-18]} {Smed: dd_Smed_v6_4392_0_1, dd_Smed_v6_4392_0_1, [Score=88.6, Expect=2e-18]} {RNA1509_36404} {RNA1310_21610.1} {RNA815_9291}
27. MligTC455_25000 632 13.16 Mlig455_016812

Neo: -

Age: logFC(26M/2M)=1.119

NPR1 0.958 - - - - - 0.958 Mlig455_016812 {REF} {Length: 4406} {Pfam: Receptor family ligand binding region [PF01094.30, score=140.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.7]; Protein kinase domain [PF00069.27, score=41.9]} {Human: ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=188, Expect=3e-49]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=188, Expect=4e-49]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=200, Expect=2e-53]} {Dmel: FBgn0051183, CG31183, [Score=192, Expect=1e-50]} {Celegans: WBGene00020131, gcy-28, Receptor-type guanylate cyclase gcy-28, [Score=182, Expect=2e-47]} {Smed: dd_Smed_v6_9955_0_1, dd_Smed_v6_9955_0_1, [Score=349, Expect=9e-106]} {RNA1509_8882} {RNA1310_1175.2} {RNA815_737}
28. MligTC455_29383 55 1.16 Mlig455_052508

Neo: -

Age: -

0.958 - - - 0.958 - - Mlig455_052508 {REF} {Length: 7465} {RNA1509_38155} {RNA1310_23095} {RNA815_16176.1}
29. MligTC455_25202 272 5.66 Mlig455_057365, Mlig455_057395

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.414/0.00124

RHOT1 0.956 - - - - - 0.956

Mlig455_057365 {REF} {Length: 5866} {Pfam: Ras family [PF00071.24, score=18.9]} {Human: ENSG00000126858, RHOT1, ras homolog family member T1, [Score=97.4, Expect=6e-20]; ENSG00000140983, RHOT2, ras homolog family member T2, [Score=93.6, Expect=9e-19]} {Mouse: ENSMUSG00000017686, Rhot1, ras homolog family member T1, [Score=97.4, Expect=4e-20]} {Dmel: FBgn0039140, Miro, Mitochondrial Rho, [Score=94.4, Expect=3e-19]} {Celegans: WBGene00019544, miro-1, Mitochondrial Rho GTPase 1, [Score=70.5, Expect=5e-12]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=92.4, Expect=1e-18]} {RNA1509_6021} {RNA1310_875.1} {RNA815_349}

Mlig455_057395 {REF} {Length: 1037} {Dmel: FBgn0050147, Hil, Hillarin, [Score=71.6, Expect=2e-13]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=62.4, Expect=1e-10]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=82.4, Expect=4e-17]} {RNA1509_6021} {RNA1310_875.1} {RNA815_349}
30. MligTC455_25204 538 11.21 Mlig455_069579

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.471

Region-enriched R3: 3.220/0.00014
Region-enriched R5: 1.890/0.03760

0.954 - - - - - 0.954 Mlig455_069579 {REF} {Length: 3907} {RNA1509_37038} {RNA1310_15345} {RNA815_1099}
31. MligTC455_43930 968 20.18 Mlig455_005369, Mlig455_036245

Neo: -

Age: -

Region-enriched R4: 1.365/0.00450
Region-enriched R5: 1.356/0.00004

ORMDL3 0.952 - - - 0.952 - -

Mlig455_005369 {REF} {Length: 2429} {TRANSSPLICED} {Pfam: ORMDL family [PF04061.16, score=160.3]} {Human: ENSG00000172057, ORMDL3, ORMDL sphingolipid biosynthesis regulator 3, [RH, Score=186, Expect=9e-61]; ENSG00000123353, ORMDL2, ORMDL sphingolipid biosynthesis regulator 2, [RH, Score=182, Expect=3e-59]} {Mouse: ENSMUSG00000038150, Ormdl3, ORM1-like 3 (S. cerevisiae), [RH, Score=186, Expect=4e-61]} {Dmel: FBgn0037110, ORMDL, [RH, Score=136, Expect=2e-41]} {Smed: dd_Smed_v6_4097_0_1, dd_Smed_v6_4097_0_1, [RH, Score=203, Expect=3e-68]} {RNA1509_32377, RNA1509_49458} {RNA1310_51157, RNA1509_32377, RNA1509_49458} {RNA1509_32377, RNA1509_49458, RNA815_18890}

Mlig455_036245 {REF} {Length: 5439} {TRANSSPLICED} {Pfam: ORMDL family [PF04061.16, score=160.3]} {Human: ENSG00000172057, ORMDL3, ORMDL sphingolipid biosynthesis regulator 3, [RH, Score=186, Expect=9e-61]; ENSG00000123353, ORMDL2, ORMDL sphingolipid biosynthesis regulator 2, [RH, Score=182, Expect=3e-59]} {Mouse: ENSMUSG00000038150, Ormdl3, ORM1-like 3 (S. cerevisiae), [RH, Score=186, Expect=4e-61]} {Dmel: FBgn0037110, ORMDL, [RH, Score=136, Expect=2e-41]} {Smed: dd_Smed_v6_4097_0_1, dd_Smed_v6_4097_0_1, [RH, Score=203, Expect=3e-68]} {RNA1509_15178, RNA1509_22377, RNA1509_44699} {RNA1310_57654, RNA1509_15178, RNA1509_22377, RNA1509_44699} {RNA1509_15178, RNA1509_22377, RNA1509_44699, RNA815_18890}
32. MligTC455_09958 142 2.96 Mlig455_013067

Neo: -

Age: -

Region-enriched R4: 4.107/0.03419

SLC5A8 0.951 - - - - - 0.951 Mlig455_013067 {REF} {Length: 3653} {Pfam: Sodium:solute symporter family [PF00474.19, score=121.3]} {Human: ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=318, Expect=1e-99]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=318, Expect=1e-99]} {Mouse: ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=319, Expect=3e-100]} {Dmel: FBgn0034494, CG10444, [Score=280, Expect=1e-85]} {Celegans: WBGene00014092, ZK822.5, [Score=218, Expect=2e-62]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=258, Expect=1e-77]} {RNA1509_54739} {RNA1310_11168} {RNA815_11120.1}
33. MligTC455_27861 431 8.98 Mlig455_016420

Neo: -

Age: -

Region-enriched R3: 2.104/0.02341

SLC22A13 0.951 - - - - - 0.951 Mlig455_016420 {REF} {Length: 2162} {Pfam: Sugar (and other) transporter [PF00083.26, score=98.2]; Major Facilitator Superfamily [PF07690.18, score=76.1]} {Human: ENSG00000172940, SLC22A13, solute carrier family 22 member 13, [Score=239, Expect=1e-71]} {Mouse: ENSMUSG00000074028, Slc22a13, solute carrier family 22 (organic cation transporter), member 13, [Score=238, Expect=4e-71]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=251, Expect=2e-76]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=174, Expect=1e-47]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=192, Expect=2e-54]} {RNA1509_38920, RNA1509_52977} {RNA1310_14607, RNA1509_38920, RNA1509_52977} {RNA1509_38920, RNA1509_52977, RNA815_16215}
34. MligTC455_19778 115 2.41 Mlig455_043422

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.387

Region-enriched R4: 3.409/0.01435

ARIH2 0.95 0.950 - - - - - Mlig455_043422 {REF} {Length: 3573} {TRANSSPLICED} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=61.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=21.2]; zinc-RING finger domain [PF14634.8, score=19.9]; RING-type zinc-finger [PF13445.8, score=19.1]} {Human: ENSG00000177479, ARIH2, ariadne RBR E3 ubiquitin protein ligase 2, [Score=315, Expect=1e-102]} {Mouse: ENSMUSG00000064145, Arih2, ariadne RBR E3 ubiquitin protein ligase 2, [Score=313, Expect=2e-102]} {Dmel: FBgn0025186, ari-2, ariadne 2, [Score=361, Expect=7e-121]} {Celegans: WBGene00020462, T12E12.1, Potential E3 ubiquitin-protein ligase ariadne-2, [Score=303, Expect=9e-99]} {Smed: dd_Smed_v6_7986_0_1, dd_Smed_v6_7986_0_1, [Score=317, Expect=1e-103]} {RNA1509_4785} {RNA1310_15084} {RNA815_5803}

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