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Results for MligTC455_05667

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_05667 30 0.63 Mlig455_042902

Neo: -

Age: -

Mlig455_042902 {REF} {Length: 1134} {RNA1509_46896} {RNA1310_11786}

Cumulative graph for MligTC455_05667

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.059 1.071 0.99993 1.00000
RegionR2 0.333 1.071 0.99957 1.00000
RegionR3 -0.01 1.071 0.99976 1.00000
RegionR4 -0.467 1.071 0.99919 1.00000
RegionR5 -0.219 1.071 0.99991 1.00000
RegionR6 -0.063 1.071 0.99983 1.00000
RegionR7 0.182 1.071 0.99978 1.00000
RegionR8 0.302 1.071 0.99976 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.176 1.071 0.99977 1.00000
RegenerationR2 4.461 1.071 0.20821 0.65598
RegenerationR3 3.855 1.071 0.33398 0.75910
RegenerationR4 4.217 1.071 0.33827 0.77039
RegenerationR5 3.787 1.071 0.26395 0.69539
RegenerationR6 5.717 1.071 0.17807 0.51198
RegenerationBL -0.008 1.071 0.99978 1.00000
RegenerationTP -0.02 1.071 0.99987 1.00000


Genes with expression patterns similar to MligTC455_05667

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_05667 30 0.63 Mlig455_042902

Neo: -

Age: -

3 - - - 1.000 1.000 1.000 Mlig455_042902 {REF} {Length: 1134} {RNA1509_46896} {RNA1310_11786}
2. MligTC455_11291 42 0.88 Mlig455_009149

Neo: Int S/G2/M

Age: -

MPV17L2 1.86 - - - 0.953 - 0.907 Mlig455_009149 {REF} {Length: 819} {TRANSSPLICED} {Pfam: Mpv17 / PMP22 family [PF04117.14, score=56.2]} {Human: ENSG00000254858, MPV17L2, MPV17 mitochondrial inner membrane protein like 2, [Score=102, Expect=1e-26]} {Mouse: ENSMUSG00000111476, Mpv17l2, MPV17 mitochondrial membrane protein-like 2, [RH, Score=102, Expect=9e-27]; ENSMUSG00000035559, Mpv17l2, MPV17 mitochondrial membrane protein-like 2, [RH, Score=102, Expect=9e-27]} {Dmel: FBgn0030481, CG1662, [RH, Score=137, Expect=5e-40]} {Celegans: WBGene00022744, ZK470.1, [RH, Score=85.5, Expect=8e-21]} {Smed: dd_Smed_v6_8288_0_1, dd_Smed_v6_8288_0_1, [RH, Score=106, Expect=9e-29]} {RNA1509_17272, RNA1509_21202, RNA1509_22178} {RNA1310_31500, RNA1509_17272, RNA1509_21202} {RNA1509_17272, RNA1509_21202, RNA815_20641}
3. MligTC455_42219 322 6.7 Mlig455_050268

Neo: Irradiation

Age: Up-Down-Down

Region-specific R4: 3.812

Region-enriched R4: 2.572/0.00001

SLC51A 0.989 - - - 0.989 - - Mlig455_050268 {REF} {Length: 3212} {Pfam: Organic solute transporter Ostalpha [PF03619.18, score=109.5]} {Human: ENSG00000163959, SLC51A, solute carrier family 51 alpha subunit, [RH, Score=57.0, Expect=1e-08]} {Mouse: ENSMUSG00000035699, Slc51a, solute carrier family 51, alpha subunit, [RH, Score=61.6, Expect=3e-10]} {Celegans: WBGene00012182, osta-3, Organic solute transporter alpha-like protein 3, [RH, Score=96.3, Expect=2e-22]} {RNA1509_16927} {RNA1310_16316} {RNA815_9480.1}
4. MligTC455_29150 23 0.49 Mlig455_029766, Mlig455_029858

Neo: -

Age: -

0.986 - - - - 0.986 -

Mlig455_029766 {REF} {Length: 567} {NoTransDecoderORF} {RNA1310_96409} {RNA815_49217.2}

Mlig455_029858 {REF} {Length: 3844} {NoTransDecoderORF} {RNA1509_47250} {RNA1310_82253} {RNA815_38239}
5. MligTC455_36668 52 1.08 Mlig455_020415

Neo: -

Age: -

0.984 - - - 0.984 - - Mlig455_020415 {REF} {Length: 1590} {RNA1310_29239.3} {RNA815_18923}
6. MligTC455_42765 49 1.03 Mlig455_055136

Neo: -

Age: logFC(26M/2M)=0.439

Region-enriched R5: 2.826/0.04177

AHNAK2 0.98 - - - 0.980 - - Mlig455_055136 {REF} {Length: 6053} {TRANSSPLICED} {Human: ENSG00000185567, AHNAK2, AHNAK nucleoprotein 2, [Score=68.2, Expect=2e-10]} {Mouse: ENSMUSG00000072812, Ahnak2, AHNAK nucleoprotein 2, [Score=51.2, Expect=1e-05]} {RNA1509_23810} {RNA1310_9986} {RNA815_12447.1}
7. MligTC455_53924 345 7.18 Mlig455_031500, Mlig455_031504

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.512/0.02739

MGAM, MGAM2 0.978 - - - 0.978 - -

Mlig455_031500 {REF} {Length: 6467} {TRANSSPLICED} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=771.4]; N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase [PF16863.7, score=128.0]; Trefoil (P-type) domain [PF00088.20, score=47.5]; Galactose mutarotase-like [PF13802.8, score=46.7]} {Human: ENSG00000282607, MGAM, maltase-glucoamylase, [RH, Score=969, Expect=0.0]; ENSG00000257335, MGAM, maltase-glucoamylase, [RH, Score=969, Expect=0.0]; ENSG00000090402, SI, sucrase-isomaltase, [RH, Score=942, Expect=0.0]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [RH, Score=969, Expect=0.0]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [RH, Score=952, Expect=0.0]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=188, Expect=3e-48]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [RH, Score=482, Expect=4e-147]} {Smed: dd_Smed_v6_1062_0_1, dd_Smed_v6_1062_0_1, [Score=466, Expect=1e-142]} {RNA1509_3169} {RNA1310_1135} {RNA815_4014}

Mlig455_031504 {REF} {Length: 414} {Human: ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=71.6, Expect=6e-15]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=71.6, Expect=6e-15]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=70.1, Expect=2e-14]; ENSG00000282607, MGAM, maltase-glucoamylase, [Score=69.7, Expect=3e-14]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=68.2, Expect=7e-14]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [Score=73.9, Expect=3e-16]} {Smed: dd_Smed_v6_1062_0_2, dd_Smed_v6_1062_0_2, [Score=58.5, Expect=6e-11]} {RNA1509_3169} {RNA1310_1135} {RNA815_943}
8. MligTC455_35218 678 14.12 Mlig455_014318

Neo: -

Age: Down-Up-Up

0.973 - - - 0.973 - - Mlig455_014318 {REF} {Length: 1896} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_21563, RNA1509_4768} {RNA1310_7742.1, RNA1509_21563, RNA1509_4768} {RNA1509_21563, RNA1509_4768, RNA815_6411}
9. MligTC455_36910 84 1.75 Mlig455_031683

Neo: -

Age: -

0.973 - - - - 0.973 - Mlig455_031683 {REF} {Length: 4716} {RNA1509_36080} {RNA1310_44068, RNA1509_36080} {RNA1509_36080, RNA815_39601}
10. MligTC455_53923 413 8.6 Mlig455_031505

Neo: -

Age: -

Region-enriched R3: 2.700/0.00511

MGAM 0.973 - - - 0.973 - - Mlig455_031505 {REF} {Length: 3805} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=338.5]} {Human: ENSG00000282607, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000090402, SI, sucrase-isomaltase, [Score=359, Expect=6e-109]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]; ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=361, Expect=6e-112]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=353, Expect=4e-107]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=150, Expect=6e-38]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [Score=364, Expect=3e-115]} {Smed: dd_Smed_v6_4668_0_1, dd_Smed_v6_4668_0_1, [Score=333, Expect=6e-104]} {RNA1509_3169} {RNA1310_1135} {RNA815_4014}
11. MligTC455_10454 39 0.81 Mlig455_009673

Neo: -

Age: -

DNASE2B 0.971 - - - - 0.971 - Mlig455_009673 {REF} {Length: 3264} {Pfam: Deoxyribonuclease II [PF03265.17, score=170.0]} {Human: ENSG00000137976, DNASE2B, deoxyribonuclease 2 beta, [Score=117, Expect=2e-28]} {Mouse: ENSMUSG00000028185, Dnase2b, deoxyribonuclease II beta, [Score=128, Expect=2e-32]} {Dmel: FBgn0000477, DNaseII, Deoxyribonuclease II, [Score=95.9, Expect=3e-21]} {Celegans: WBGene00000799, crn-6, Cell death-related nuclease 6, [Score=103, Expect=8e-24]} {Smed: dd_Smed_v6_1691_0_1, dd_Smed_v6_1691_0_1, [Score=113, Expect=2e-27]} {RNA1509_52192} {RNA1310_16913} {RNA815_10835}
12. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 0.97 - - - 0.970 - - Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
13. MligTC455_26259 76 1.59 Mlig455_026466

Neo: -

Age: -

SSUH2 0.969 - - - - 0.969 - Mlig455_026466 {REF} {Length: 2558} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=211, Expect=9e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=168, Expect=6e-48]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=67.8, Expect=3e-12]} {RNA1509_35931} {RNA1310_33249} {RNA815_15534}
14. MligTC455_49771 61 1.26 Mlig455_018423

Neo: -

Age: -

0.968 - - - 0.968 - - Mlig455_018423 {REF} {Length: 2813} {RNA1509_25822} {RNA1310_57791} {RNA815_29848}
15. MligTC455_50035 432 9 Mlig455_000039

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.574/0.01215

SPHK1 0.968 - - - 0.968 - - Mlig455_000039 {REF} {Length: 2459} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=79.4]; YegS C-terminal NAD kinase beta sandwich-like domain [PF19279.1, score=29.9]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [RH, Score=215, Expect=5e-64]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=206, Expect=1e-60]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [Score=142, Expect=1e-35]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [RH, Score=149, Expect=5e-39]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [RH, Score=174, Expect=1e-48]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
16. MligTC455_52799 80 1.66 Mlig455_031263

Neo: -

Age: -

0.967 - - - - 0.967 - Mlig455_031263 {REF} {Length: 2630} {TRANSSPLICED} {Pfam: Yippee zinc-binding/DNA-binding /Mis18, centromere assembly [PF03226.16, score=19.0]} {Celegans: WBGene00011139, R08B4.3, [RH, Score=67.4, Expect=2e-14]} {RNA1509_40856, RNA1509_47857} {RNA1310_46338, RNA1509_40856} {RNA1509_40856, RNA815_34349}
17. MligTC455_12517 587 12.23 Mlig455_023517

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.412

0.966 - - - 0.966 - - Mlig455_023517 {REF} {Length: 661} {RNA1509_22223} {RNA1310_60769} {RNA815_31256}
18. MligTC455_14499 35 0.73 Mlig455_052131

Neo: -

Age: -

0.966 - - - - 0.966 - Mlig455_052131 {REF} {Length: 203} {NoTransDecoderORF} {RNA1310_10102} {RNA815_11180}
19. MligTC455_21785 107 2.24 Mlig455_005064

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-0.389

KRIT1 0.966 - - - - 0.966 - Mlig455_005064 {REF} {Length: 4037} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.0]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeats (many copies) [PF13637.8, score=40.3]; Ankyrin repeat [PF00023.32, score=35.8]; Ankyrin repeat [PF13606.8, score=32.7]; FERM central domain [PF00373.20, score=26.3]} {Human: ENSG00000001631, KRIT1, KRIT1, ankyrin repeat containing, [RH, Score=218, Expect=2e-60]; ENSG00000285953, AC000120.3, novel protein, [RH, Score=209, Expect=2e-57]} {Mouse: ENSMUSG00000000600, Krit1, KRIT1, ankyrin repeat containing, [RH, Score=207, Expect=1e-56]} {Dmel: FBgn0029137, Patsas, [Score=51.6, Expect=2e-06]} {Celegans: WBGene00013955, kri-1, KRIT 1 (Krev interaction trapped/cerebral cavernous malformation 1) homolog; Krev interaction trapped/cerebral cavernous malformation 1 isoform a, [RH, Score=85.9, Expect=5e-17]} {Smed: dd_Smed_v6_10935_0_1, dd_Smed_v6_10935_0_1, [RH, Score=137, Expect=3e-33]} {RNA1509_17918} {RNA1310_6799, RNA1509_17918} {RNA1509_17918, RNA815_1724}
20. MligTC455_42437 135 2.82 Mlig455_046015

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.377

Region-enriched R4: 4.645/0.00175

0.964 - - - 0.964 - - Mlig455_046015 {REF} {Length: 5259} {Pfam: Pyruvate phosphate dikinase, AMP/ATP-binding domain [PF01326.21, score=155.0]; PEP-utilising enzyme, mobile domain [PF00391.25, score=76.2]} {Celegans: WBGene00011893, T21C9.6, [Score=245, Expect=5e-67]} {Smed: dd_Smed_v6_2604_0_1, dd_Smed_v6_2604_0_1, [Score=591, Expect=0.0]} {RNA1509_11691} {RNA1310_1331} {RNA815_563}
21. MligTC455_43327 11 0.22 Mlig455_036664

Neo: -

Age: -

0.963 - - - - 0.963 - Mlig455_036664 {REF} {Length: 590} {NoTransDecoderORF} {RNA1509_18111} {RNA1310_77247} {RNA815_11759.2}
22. MligTC455_29131 123 2.57 Mlig455_037013

Neo: -

Age: -

Region-enriched R3: 4.542/0.00028
Region-enriched R5: 3.258/0.00981

0.962 - - - 0.962 - - Mlig455_037013 {REF} {Length: 2178} {RNA1509_47002} {RNA1310_12462.2} {RNA815_6311.1}
23. MligTC455_23304 1206 25.12 Mlig455_036050

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.727/0.00398

CH25H 0.961 - - - 0.961 - - Mlig455_036050 {REF} {Length: 2059} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=77.6]} {Human: ENSG00000138135, CH25H, cholesterol 25-hydroxylase, [RH, Score=168, Expect=6e-50]} {Mouse: ENSMUSG00000050370, Ch25h, cholesterol 25-hydroxylase, [RH, Score=182, Expect=2e-55]} {Celegans: WBGene00018036, F35C8.5, Cholesterol 25-hydroxylase-like protein, [RH, Score=201, Expect=1e-62]} {RNA1509_10839, RNA1509_11085, RNA1509_2104, RNA1509_51868} {RNA1310_8947, RNA1509_10839, RNA1509_11085, RNA1509_51868} {RNA1509_10839, RNA1509_11085, RNA1509_51868, RNA815_835.1}
24. MligTC455_35670 353 7.35 Mlig455_000478, Mlig455_000513

Neo: -

Age: logFC(26M/2M)=0.556

AC099489.1 0.961 - - - 0.961 - -

Mlig455_000478 {REF} {Length: 11127} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=93.5]; Domain of unknown function (DUF1943) [PF09172.13, score=67.6]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=131, Expect=1e-29]} {Dmel: FBgn0087002, apolpp, apolipophorin, [Score=61.2, Expect=8e-09]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=91.7, Expect=3e-18]} {RNA1509_27087, RNA1509_28440} {RNA1310_65.2, RNA1509_28440} {RNA1509_28440, RNA815_55}

Mlig455_000513 {REF} {Length: 2538} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=41.7]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=68.6, Expect=2e-11]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=60.8, Expect=2e-09]} {RNA1509_27087} {RNA1310_65.2} {RNA815_55}
25. MligTC455_38825 11 0.23 Mlig455_039405

Neo: -

Age: -

0.961 - - - - 0.961 - Mlig455_039405 {REF} {Length: 2870} {RNA1509_50426} {RNA1310_112749} {RNA815_26544}
26. MligTC455_44699 2074 43.2 Mlig455_048395

Neo: -

Age: logFC(26M/2M)=0.553

Region-enriched R3: 1.711/0.00637

SLC10A5 0.961 - - - 0.961 - - Mlig455_048395 {REF} {Length: 1771} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=116.4]} {Human: ENSG00000253598, SLC10A5, solute carrier family 10 member 5, [RH, Score=130, Expect=9e-33]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=129, Expect=4e-33]; ENSMUSG00000058921, Slc10a5, solute carrier family 10 (sodium/bile acid cotransporter family), member 5, [Score=125, Expect=6e-31]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=9e-31]} {Dmel: FBgn0030756, CG9903, [Score=103, Expect=1e-23]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=206, Expect=4e-60]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [RH, Score=295, Expect=3e-95]} {RNA1509_51285} {RNA1310_359.1} {RNA815_3102}
27. MligTC455_17882 4410 91.87 Mlig455_017550, Mlig455_030854

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-1.153

Region-enriched R6: 2.434/0.00204
Region-enriched R5: 1.911/0.00431
Region-enriched R3: 1.811/0.04295

Regeneration-upregulated TP: 4.451

Regeneration-enriched TP: 4.451

0.96 - - - 0.960 - -

Mlig455_017550 {REF} {Length: 2052} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=68.3]} {RNA1509_5435} {RNA1310_16003} {RNA815_8431}

Mlig455_030854 {REF} {Length: 1811} {RNA1509_41365, RNA1509_5435} {RNA1310_16003, RNA1509_41365} {RNA1509_41365, RNA815_8431}
28. MligTC455_49841 536 11.17 Mlig455_054891

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R5: 1.350/0.04241

MMEL1 0.959 - - - 0.959 - - Mlig455_054891 {REF} {Length: 2632} {Pfam: Peptidase family M13 [PF05649.15, score=201.7]; Peptidase family M13 [PF01431.23, score=93.2]} {Human: ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=181, Expect=4e-47]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=9e-46]; ENSG00000145194, ECE2, endothelin converting enzyme 2, [Score=176, Expect=3e-45]; ENSG00000284917, EEF1AKMT4-ECE2, EEF1AKMT4-ECE2 readthrough, [Score=175, Expect=9e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=194, Expect=7e-52]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=187, Expect=4e-49]} {Celegans: WBGene00017557, nep-11, Neprilysin-11, [Score=158, Expect=8e-40]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=167, Expect=5e-43]} {RNA1509_16049, RNA1509_48689} {RNA1310_4911.1, RNA1509_48689} {RNA1509_48689, RNA815_2994}
29. MligTC455_19299 65 1.35 Mlig455_001048

Neo: -

Age: -

0.958 - - - 0.958 - - Mlig455_001048 {REF} {Length: 2071} {NoTransDecoderORF} {RNA1310_76604}
30. MligTC455_23305 524 10.91 Mlig455_054093

Neo: -

Age: -

Region-enriched R3: 1.848/0.00073
Region-enriched R4: 1.814/0.00794

CH25H 0.958 - - - 0.958 - - Mlig455_054093 {REF} {Length: 2052} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=77.6]} {Human: ENSG00000138135, CH25H, cholesterol 25-hydroxylase, [RH, Score=168, Expect=7e-50]} {Mouse: ENSMUSG00000050370, Ch25h, cholesterol 25-hydroxylase, [RH, Score=182, Expect=3e-55]} {Celegans: WBGene00018036, F35C8.5, Cholesterol 25-hydroxylase-like protein, [RH, Score=199, Expect=6e-62]} {RNA1509_13990, RNA1509_16293, RNA1509_2104} {RNA1310_8947, RNA1509_13990, RNA1509_16293, RNA1509_2104} {RNA1509_13990, RNA1509_16293, RNA1509_2104, RNA815_835.1}
31. MligTC455_32332 20 0.43 Mlig455_031157

Neo: -

Age: Up-Down-Up

0.958 - - - - 0.958 - Mlig455_031157 {REF} {Length: 2930} {RNA1509_59088} {RNA1310_38580} {RNA815_39994}
32. MligTC455_30312 52 1.09 Mlig455_064890

Neo: -

Age: logFC(26M/2M)=-0.341

MAP3K19 0.957 - - - - 0.957 - Mlig455_064890 {REF} {Length: 3703} {Pfam: Protein kinase domain [PF00069.27, score=186.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=138.8]; Ankyrin repeats (3 copies) [PF12796.9, score=63.4]; Ankyrin repeats (many copies) [PF13637.8, score=62.5]; Ankyrin repeats (many copies) [PF13857.8, score=41.8]; Ankyrin repeat [PF00023.32, score=37.4]; Ankyrin repeat [PF13606.8, score=31.0]; ABC1 atypical kinase-like domain [PF03109.18, score=28.7]; Fungal protein kinase [PF17667.3, score=27.3]; Phosphotransferase enzyme family [PF01636.25, score=20.7]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=153, Expect=8e-40]; ENSG00000072786, STK10, serine/threonine kinase 10, [Score=151, Expect=6e-38]; ENSG00000065613, SLK, STE20 like kinase, [Score=147, Expect=2e-36]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=157, Expect=2e-41]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=149, Expect=4e-38]} {Celegans: WBGene00022603, gck-2, Mitogen-activated protein kinase kinase kinase kinase, [Score=135, Expect=4e-33]} {Smed: dd_Smed_v6_9984_0_1, dd_Smed_v6_9984_0_1, [Score=140, Expect=4e-37]} {RNA1509_25652} {RNA1310_24355.1} {RNA815_2803.1}
33. MligTC455_38068 131 2.74 Mlig455_069951

Neo: -

Age: Up-Down-Down

ANO7 0.957 - - - - 0.957 - Mlig455_069951 {REF} {Length: 5066} {TRANSSPLICED} {Pfam: Calcium-activated chloride channel [PF04547.14, score=419.3]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=87.9]; PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=25.1]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=301, Expect=4e-87]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=303, Expect=7e-89]} {Dmel: FBgn0036235, CG6938, [Score=266, Expect=6e-74]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=414, Expect=2e-130]} {Smed: dd_Smed_v6_5046_0_1, dd_Smed_v6_5046_0_1, [Score=279, Expect=1e-80]} {RNA1509_23151} {RNA1310_3473} {RNA815_7212}
34. MligTC455_24085 1786 37.2 Mlig455_007320

Neo: -

Age: logFC(26M/2M)=0.210

Region-enriched R3: 2.481/0.00000
Region-enriched R5: 1.136/0.04856

ACHE 0.956 - - - 0.956 - - Mlig455_007320 {REF} {Length: 2268} {Pfam: Carboxylesterase family [PF00135.30, score=353.8]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=232, Expect=2e-67]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=227, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=202, Expect=2e-56]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=223, Expect=2e-64]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=206, Expect=5e-58]} {RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1310_10437.1, RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1509_28908, RNA1509_31228, RNA1509_46106, RNA815_3976}
35. MligTC455_13131 387 8.05 Mlig455_026023

Neo: -

Age: logFC(26M/2M)=0.509

Region-enriched R4: 1.750/0.02424

CALM2 0.955 - - - 0.955 - - Mlig455_026023 {REF} {Length: 1136} {Pfam: EF-hand domain [PF14658.8, score=22.4]; EF hand [PF00036.34, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=59.7, Expect=8e-11]; ENSG00000160014, CALM3, calmodulin 3, [Score=58.9, Expect=9e-11]; ENSG00000198668, CALM1, calmodulin 1, [Score=58.9, Expect=9e-11]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=58.9, Expect=6e-11]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=58.9, Expect=6e-11]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=58.9, Expect=6e-11]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=58.9, Expect=7e-11]} {Dmel: FBgn0004687, Mlc-c, Myosin light chain cytoplasmic, [Score=58.9, Expect=5e-11]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=57.4, Expect=1e-10]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=57.4, Expect=1e-10]} {RNA1509_43009} {RNA1310_29863, RNA1509_43009} {RNA1509_43009, RNA815_15472.1}
36. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

0.955 - - - 0.955 - - Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
37. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

0.955 - - - 0.955 - - Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
38. MligTC455_32089 32 0.66 Mlig455_040995

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_040995 {REF} {Length: 754} {NoTransDecoderORF} {RNA1509_49715} {RNA1310_24655} {RNA815_31399}
39. MligTC455_40572 206 4.28 Mlig455_055867

Neo: -

Age: Up-Down-Up

Region-enriched R3: 3.069/0.00971
Region-enriched R4: 2.734/0.03821

SMOX 0.954 - - - 0.954 - - Mlig455_055867 {REF} {Length: 3423} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=186.6]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=52.5]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=22.8]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=21.8]; FAD dependent oxidoreductase [PF01266.26, score=21.0]; FAD binding domain [PF00890.26, score=18.3]} {Human: ENSG00000088826, SMOX, spermine oxidase, [RH, Score=134, Expect=2e-33]} {Mouse: ENSMUSG00000027333, Smox, spermine oxidase, [RH, Score=133, Expect=3e-33]} {Dmel: FBgn0036749, CG7460, [RH, Score=144, Expect=8e-38]} {Celegans: WBGene00016061, hpo-15, [RH, Score=132, Expect=4e-33]} {Smed: dd_Smed_v6_20536_0_1, dd_Smed_v6_20536_0_1, [RH, Score=63.5, Expect=9e-11]} {RNA1509_44166} {RNA1310_14670.1, RNA1509_44166} {RNA1509_44166, RNA815_11013}
40. MligTC455_14550 82 1.72 Mlig455_016928

Neo: -

Age: Down-Up-Up

Region-enriched R4: 4.810/0.01442

GRASP 0.953 - - - 0.953 - - Mlig455_016928 {REF} {Length: 1233} {Pfam: PDZ domain [PF17820.3, score=33.1]; PDZ domain [PF00595.26, score=25.0]} {Human: ENSG00000161835, GRASP, general receptor for phosphoinositides 1 associated scaffold protein, [RH, Score=55.8, Expect=5e-09]} {Mouse: ENSMUSG00000000531, Grasp, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, [RH, Score=58.5, Expect=5e-10]} {Dmel: FBgn0035676, ssp6, short spindle 6, [RH, Score=87.8, Expect=3e-20]} {Celegans: WBGene00009272, gras-1, GRASP (General Receptor for phosphoinositides 1-Associated Scaffold Protein) homolog, [RH, Score=64.7, Expect=9e-13]} {RNA1509_57284} {RNA1310_36717} {RNA815_20577}
41. MligTC455_19213 332 6.92 Mlig455_027303

Neo: -

Age: -

Region-enriched R4: 3.653/0.00406
Region-enriched R3: 2.959/0.01217
Region-enriched R5: 2.470/0.02256

HSD11B1 0.953 - - - 0.953 - - Mlig455_027303 {REF} {Length: 1227} {Pfam: short chain dehydrogenase [PF00106.27, score=127.7]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.9]; KR domain [PF08659.12, score=25.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=161, Expect=2e-47]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=79.7, Expect=4e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_4614_0_1, dd_Smed_v6_4614_0_1, [Score=72.4, Expect=1e-14]} {RNA1509_41682} {RNA1310_27439} {RNA815_13316}
42. MligTC455_19827 25 0.52 Mlig455_041824

Neo: Germline

Age: -

CSNK1A1 0.953 - - - 0.953 - - Mlig455_041824 {REF} {Length: 3035} {Human: ENSG00000113712, CSNK1A1, casein kinase 1 alpha 1, [Score=60.1, Expect=6e-09]} {Mouse: ENSMUSG00000024576, Csnk1a1, casein kinase 1, alpha 1, [Score=60.1, Expect=4e-09]} {Dmel: FBgn0037325, CG12147, [Score=62.4, Expect=9e-10]} {Celegans: WBGene00002202, kin-19, Casein kinase I isoform alpha, [Score=68.6, Expect=4e-12]} {Smed: dd_Smed_v6_12103_0_1, dd_Smed_v6_12103_0_1, [Score=65.1, Expect=3e-11]} {RNA1509_32782} {RNA1310_8866.1, RNA1509_32782} {RNA1509_32782, RNA815_11402.1}
43. MligTC455_51747 32 0.66 Mlig455_019791, Mlig455_019810

Neo: -

Age: -

0.953 - - - - 0.953 -

Mlig455_019791 {REF} {Length: 1662} {tRNA: Undet(NNN),pseudo, score=21.8} {RNA1509_26806} {RNA1310_54539} {RNA815_44342}

Mlig455_019810 {REF} {Length: 1680} {tRNA: Undet(NNN),pseudo, score=20.2} {RNA1509_45595} {RNA1310_54539} {RNA815_44342}
44. MligTC455_48088 154 3.21 Mlig455_069669

Neo: -

Age: -

0.952 - - - - - 0.952 Mlig455_069669 {REF} {Length: 1538} {NoTransDecoderORF} {RNA1509_23706} {RNA1310_39789} {RNA815_19330.1}
45. MligTC455_50036 1353 28.19 Mlig455_063714

Neo: -

Age: logFC(26M/2M)=-0.294

Region-enriched R4: 1.826/0.00071
Region-enriched R3: 1.745/0.00078
Region-enriched R5: 1.202/0.01353

SPHK1 0.952 - - - 0.952 - - Mlig455_063714 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=81.8]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=152, Expect=4e-43]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=150, Expect=5e-44]; ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [RH, Score=145, Expect=1e-39]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=120, Expect=2e-31]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=127, Expect=3e-34]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
46. MligTC455_10035 177 3.7 Mlig455_070770

Neo: Irradiation

Age: Down-Down-Down, logFC(26M/2M)=-1.114

0.951 - - - - 0.951 - Mlig455_070770 {REF} {Length: 1452} {NoTransDecoderORF} {RNA1509_18811} {RNA1310_39704} {RNA815_51915}
47. MligTC455_35770 270 5.63 Mlig455_061794

Neo: Germline

Age: logFC(26M/2M)=-0.353

Region-specific R4: 4.388

Region-enriched R4: 2.622/0.01221

0.951 - - - 0.951 - - Mlig455_061794 {REF} {Length: 1977} {NoTransDecoderORF} {RNA1509_25218} {RNA1310_30831} {RNA815_5930}
48. MligTC455_43417 52 1.07 Mlig455_057452

Neo: -

Age: -

KCNK13 0.951 - - - - - 0.951 Mlig455_057452 {REF} {Length: 2055} {TRANSSPLICED} {Pfam: Ion channel [PF07885.18, score=86.0]; Ion transport protein [PF00520.33, score=25.2]} {Human: ENSG00000152315, KCNK13, potassium two pore domain channel subfamily K member 13, [RH, Score=318, Expect=7e-105]; ENSG00000184261, KCNK12, potassium two pore domain channel subfamily K member 12, [RH, Score=307, Expect=3e-100]} {Mouse: ENSMUSG00000050138, Kcnk12, potassium channel, subfamily K, member 12, [RH, Score=318, Expect=2e-104]} {Dmel: FBgn0037690, Task7, TWIK-related acid-sensitive K[+] channel 7, [Score=105, Expect=7e-25]} {Celegans: WBGene00006669, twk-14, TWiK family of potassium channels, [RH, Score=241, Expect=2e-74]} {Smed: dd_Smed_v6_15695_0_1, dd_Smed_v6_15695_0_1, [Score=80.9, Expect=3e-16]} {RNA1509_42705} {RNA1310_65121} {RNA815_42759}
49. MligTC455_18923 743 15.48 Mlig455_063038

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.791

Region-enriched R4: 2.273/0.01537

0.95 - - - 0.950 - - Mlig455_063038 {REF} {Length: 1906} {RNA1509_26120} {RNA1310_29982} {RNA815_3607}
50. MligTC455_38061 112 2.33 Mlig455_003183, Mlig455_003385

Neo: -

Age: Down-Up-Down

Region-enriched R4: 3.963/0.00323
Region-enriched R3: 2.923/0.03513

SLC22A5 0.95 - - - 0.950 - -

Mlig455_003183 {REF} {Length: 2030} {Pfam: Sugar (and other) transporter [PF00083.26, score=94.4]; Major Facilitator Superfamily [PF07690.18, score=79.2]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=251, Expect=1e-75]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=247, Expect=3e-74]} {Mouse: ENSMUSG00000020334, Slc22a4, solute carrier family 22 (organic cation transporter), member 4, [Score=250, Expect=1e-75]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=248, Expect=2e-74]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=272, Expect=3e-84]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=233, Expect=4e-69]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=211, Expect=3e-61]} {RNA1310_28487} {RNA815_52073}

Mlig455_003385 {REF} {Length: 2374} {Pfam: Major Facilitator Superfamily [PF07690.18, score=37.9]; Sugar (and other) transporter [PF00083.26, score=28.3]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=113, Expect=5e-26]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=111, Expect=2e-25]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=110, Expect=2e-25]; ENSMUSG00000018900, Slc22a5, solute carrier family 22 (organic cation transporter), member 5, [Score=107, Expect=2e-24]; ENSMUSG00000020334, Slc22a4, solute carrier family 22 (organic cation transporter), member 4, [Score=105, Expect=7e-24]} {Dmel: FBgn0086365, Orct2, Organic cation transporter 2, [Score=134, Expect=1e-33]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=100, Expect=3e-22]} {RNA1310_28487} {RNA815_52073}
51. MligTC455_50387 1074 22.38 Mlig455_018618

Neo: -

Age: logFC(26M/2M)=0.362

Region-enriched R4: 2.247/0.00001
Region-enriched R3: 1.935/0.00000

SLC8B1 0.95 - - - 0.950 - - Mlig455_018618 {REF} {Length: 2020} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=96.0]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=214, Expect=1e-62]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=220, Expect=4e-65]} {Dmel: FBgn0033324, CG14744, [Score=126, Expect=8e-31]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=168, Expect=3e-45]} {Smed: dd_Smed_v6_1009_1_1, dd_Smed_v6_1009_1_1, [RH, Score=254, Expect=2e-80]} {RNA1509_17694, RNA1509_27887, RNA1509_3073} {RNA1310_3165.1, RNA1509_17694, RNA1509_27887} {RNA1509_17694, RNA1509_27887, RNA815_1390}

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