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Results for MligTC455_49841

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49841 536 11.17 Mlig455_054891

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R5: 1.350/0.04241

MMEL1 Mlig455_054891 {REF} {Length: 2632} {Pfam: Peptidase family M13 [PF05649.15, score=201.7]; Peptidase family M13 [PF01431.23, score=93.2]} {Human: ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=181, Expect=4e-47]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=9e-46]; ENSG00000145194, ECE2, endothelin converting enzyme 2, [Score=176, Expect=3e-45]; ENSG00000284917, EEF1AKMT4-ECE2, EEF1AKMT4-ECE2 readthrough, [Score=175, Expect=9e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=194, Expect=7e-52]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=187, Expect=4e-49]} {Celegans: WBGene00017557, nep-11, Neprilysin-11, [Score=158, Expect=8e-40]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=167, Expect=5e-43]} {RNA1509_16049, RNA1509_48689} {RNA1310_4911.1, RNA1509_48689} {RNA1509_48689, RNA815_2994}

Cumulative graph for MligTC455_49841

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.397 3.953 0.29596 0.94727
RegionR2 -2.017 3.953 0.02370 0.17120
RegionR3 1.335 3.953 0.01488 0.19650
RegionR4 0.867 3.953 0.17249 0.43714
RegionR5 1.35 3.953 0.00653 0.04241
RegionR6 1.157 3.953 0.04222 0.38492
RegionR7 -2.782 3.953 0.01628 0.23110
RegionR8 -1.307 3.953 0.33017 0.96323

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -2.117 3.953 0.26170 0.96822
RegenerationR2 0.604 3.953 0.42178 0.82844
RegenerationR3 -0.585 3.953 0.34706 0.76922
RegenerationR4 -0.228 3.953 0.71880 0.96095
RegenerationR5 -0.545 3.953 0.34600 0.76113
RegenerationR6 -0.41 3.953 0.50231 0.80785
RegenerationBL 0.905 3.953 0.31091 0.67636
RegenerationTP -0.534 3.953 0.72320 1.00000


Genes with expression patterns similar to MligTC455_49841

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49841 536 11.17 Mlig455_054891

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R5: 1.350/0.04241

MMEL1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_054891 {REF} {Length: 2632} {Pfam: Peptidase family M13 [PF05649.15, score=201.7]; Peptidase family M13 [PF01431.23, score=93.2]} {Human: ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=182, Expect=2e-47]; ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=181, Expect=4e-47]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=9e-46]; ENSG00000145194, ECE2, endothelin converting enzyme 2, [Score=176, Expect=3e-45]; ENSG00000284917, EEF1AKMT4-ECE2, EEF1AKMT4-ECE2 readthrough, [Score=175, Expect=9e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=194, Expect=7e-52]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=187, Expect=4e-49]} {Celegans: WBGene00017557, nep-11, Neprilysin-11, [Score=158, Expect=8e-40]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=167, Expect=5e-43]} {RNA1509_16049, RNA1509_48689} {RNA1310_4911.1, RNA1509_48689} {RNA1509_48689, RNA815_2994}
2. MligTC455_41503 3372 70.25 Mlig455_015421

Neo: -

Age: -

Region-enriched R3: 1.663/0.00123

4.164 - 0.885 0.819 0.975 0.728 0.757 Mlig455_015421 {REF} {Length: 3377} {Pfam: Fasciclin domain [PF02469.24, score=41.0]} {Dmel: FBgn0032638, SPH93, Serine protease homolog 93, [Score=61.6, Expect=2e-09]} {RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1310_8987, RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1509_26815, RNA1509_27548, RNA1509_56488, RNA815_3084.1}
3. MligTC455_19213 332 6.92 Mlig455_027303

Neo: -

Age: -

Region-enriched R4: 3.653/0.00406
Region-enriched R3: 2.959/0.01217
Region-enriched R5: 2.470/0.02256

HSD11B1 3.954 - 0.716 0.760 0.963 0.810 0.705 Mlig455_027303 {REF} {Length: 1227} {Pfam: short chain dehydrogenase [PF00106.27, score=127.7]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=83.9]; KR domain [PF08659.12, score=25.0]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=161, Expect=2e-47]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=151, Expect=1e-43]} {Dmel: FBgn0051548, CG31548, [Score=79.7, Expect=4e-17]} {Celegans: WBGene00019885, R05D8.7, [Score=80.1, Expect=3e-17]} {Smed: dd_Smed_v6_4614_0_1, dd_Smed_v6_4614_0_1, [Score=72.4, Expect=1e-14]} {RNA1509_41682} {RNA1310_27439} {RNA815_13316}
4. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

3.365 - 0.709 - 0.971 0.919 0.766

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
5. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 3.312 - 0.738 - 0.962 0.817 0.795 Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
6. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

SLC3A1 3.308 - 0.732 - 0.963 0.817 0.796 Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
7. MligTC455_48071 1712 35.67 Mlig455_048082

Neo: -

Age: logFC(26M/2M)=-0.321

Region-enriched R4: 1.489/0.04451

HSD11B1 3.287 - - 0.715 0.962 0.813 0.797 Mlig455_048082 {REF} {Length: 1293} {Pfam: short chain dehydrogenase [PF00106.27, score=123.3]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.2]; KR domain [PF08659.12, score=26.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=155, Expect=4e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=150, Expect=1e-43]} {Dmel: FBgn0027583, CG7601, [Score=82.4, Expect=9e-18]} {Celegans: WBGene00000982, dhs-19, DeHydrogenases, Short chain, [Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_4976_0_1, dd_Smed_v6_4976_0_1, [Score=62.8, Expect=3e-11]} {RNA1509_14549, RNA1509_28912} {RNA1310_26648, RNA1509_14549, RNA1509_28912} {RNA1509_14549, RNA1509_28912, RNA815_11342}
8. MligTC455_42352 5331 111.06 Mlig455_014325

Neo: -

Age: -

Region-enriched R3: 1.607/0.00131
Region-enriched R5: 1.102/0.02723

ACE 3.262 - 0.835 - 0.963 0.725 0.739 Mlig455_014325 {REF} {Length: 2705} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441, RNA1509_9027} {RNA1310_8949, RNA1509_441, RNA1509_9027} {RNA1509_441, RNA1509_9027, RNA815_4061}
9. MligTC455_38613 969 20.2 Mlig455_048005, Mlig455_063705

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.394

Region-enriched R3: 1.570/0.01256

POSTN 3.173 - 0.789 - 0.964 0.710 0.710

Mlig455_048005 {REF} {Length: 629} {Pfam: Fasciclin domain [PF02469.24, score=22.3]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=52.0, Expect=7e-08]} {RNA1509_6801} {RNA1310_9258} {RNA815_5083}

Mlig455_063705 {REF} {Length: 2741} {Pfam: Fasciclin domain [PF02469.24, score=65.6]} {Human: ENSG00000133110, POSTN, periostin, [Score=67.0, Expect=9e-11]} {Mouse: ENSMUSG00000027750, Postn, periostin, osteoblast specific factor, [Score=63.5, Expect=7e-10]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=141, Expect=9e-35]} {RNA1509_45570, RNA1509_6801} {RNA1310_9258, RNA1509_45570, RNA1509_6801} {RNA1509_45570, RNA1509_6801, RNA815_5083}
10. MligTC455_20060 2538 52.87 Mlig455_063008

Neo: -

Age: logFC(26M/2M)=0.327

AMT 2.728 - - - 0.938 0.950 0.840 Mlig455_063008 {REF} {Length: 1813} {TRANSSPLICED} {Pfam: Aminomethyltransferase folate-binding domain [PF01571.23, score=260.3]; Glycine cleavage T-protein C-terminal barrel domain [PF08669.13, score=63.7]} {Human: ENSG00000145020, AMT, aminomethyltransferase, [RH, Score=337, Expect=6e-113]} {Mouse: ENSMUSG00000032607, Amt, aminomethyltransferase, [RH, Score=341, Expect=2e-114]} {Dmel: FBgn0032287, CG6415, [RH, Score=308, Expect=9e-102]} {Celegans: WBGene00017765, gcst-1, Aminomethyltransferase, [RH, Score=298, Expect=6e-98]} {Smed: dd_Smed_v6_3994_0_1, dd_Smed_v6_3994_0_1, [RH, Score=346, Expect=1e-116]} {RNA1509_21672} {RNA1310_17248.1} {RNA815_1503.1}
11. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 2.613 - - - 0.963 0.838 0.812

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
12. MligTC455_50387 1074 22.38 Mlig455_018618

Neo: -

Age: logFC(26M/2M)=0.362

Region-enriched R4: 2.247/0.00001
Region-enriched R3: 1.935/0.00000

SLC8B1 2.549 - - - 0.971 0.795 0.783 Mlig455_018618 {REF} {Length: 2020} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=96.0]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=214, Expect=1e-62]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=220, Expect=4e-65]} {Dmel: FBgn0033324, CG14744, [Score=126, Expect=8e-31]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=168, Expect=3e-45]} {Smed: dd_Smed_v6_1009_1_1, dd_Smed_v6_1009_1_1, [RH, Score=254, Expect=2e-80]} {RNA1509_17694, RNA1509_27887, RNA1509_3073} {RNA1310_3165.1, RNA1509_17694, RNA1509_27887} {RNA1509_17694, RNA1509_27887, RNA815_1390}
13. MligTC455_35670 353 7.35 Mlig455_000478, Mlig455_000513

Neo: -

Age: logFC(26M/2M)=0.556

AC099489.1 2.542 - - - 0.955 0.814 0.773

Mlig455_000478 {REF} {Length: 11127} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=93.5]; Domain of unknown function (DUF1943) [PF09172.13, score=67.6]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=131, Expect=1e-29]} {Dmel: FBgn0087002, apolpp, apolipophorin, [Score=61.2, Expect=8e-09]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=91.7, Expect=3e-18]} {RNA1509_27087, RNA1509_28440} {RNA1310_65.2, RNA1509_28440} {RNA1509_28440, RNA815_55}

Mlig455_000513 {REF} {Length: 2538} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=41.7]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=68.6, Expect=2e-11]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=60.8, Expect=2e-09]} {RNA1509_27087} {RNA1310_65.2} {RNA815_55}
14. MligTC455_35218 678 14.12 Mlig455_014318

Neo: -

Age: Down-Up-Up

2.529 - - - 0.954 0.779 0.796 Mlig455_014318 {REF} {Length: 1896} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_21563, RNA1509_4768} {RNA1310_7742.1, RNA1509_21563, RNA1509_4768} {RNA1509_21563, RNA1509_4768, RNA815_6411}
15. MligTC455_36665 2410 50.21 Mlig455_028654

Neo: -

Age: logFC(26M/2M)=0.273

Region-enriched R3: 1.404/0.00674

PSAP 2.526 - - - 0.967 0.839 0.720 Mlig455_028654 {REF} {Length: 3951} {Pfam: Saposin-like type B, region 1 [PF05184.17, score=340.1]; Saposin-like type B, region 2 [PF03489.19, score=316.5]; Homeodomain-like domain [PF13384.8, score=47.9]; Helix-turn-helix domain [PF13518.8, score=39.6]; Saposin A-type domain [PF02199.17, score=35.5]; Protein of unknown function (DUF2753) [PF10952.10, score=31.0]; Replication factor RFC1 C terminal domain [PF08519.14, score=24.2]; Winged helix-turn helix [PF13551.8, score=23.7]; HD domain [PF13023.8, score=21.9]; Delta endotoxin [PF18449.3, score=19.6]} {Human: ENSG00000197746, PSAP, prosaposin, [RH, Score=177, Expect=9e-47]} {Mouse: ENSMUSG00000004207, Psap, prosaposin, [RH, Score=154, Expect=6e-39]} {Dmel: FBgn0000416, Sap-r, Saposin-related, [RH, Score=245, Expect=3e-67]} {Smed: dd_Smed_v6_266_0_1, dd_Smed_v6_266_0_1, [Score=99.0, Expect=1e-22]} {RNA1509_1917} {RNA1310_9056} {RNA815_5033.1}
16. MligTC455_50388 1031 21.47 Mlig455_018603, Mlig455_018617

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.979/0.00000
Region-enriched R4: 1.829/0.00016

SLC8B1 2.508 - - - 0.964 0.751 0.793

Mlig455_018603 {REF} {Length: 3460} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=150.9]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [RH, Score=215, Expect=5e-60]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [RH, Score=222, Expect=1e-62]} {Dmel: FBgn0033324, CG14744, [Score=127, Expect=4e-30]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [RH, Score=169, Expect=8e-44]} {Smed: dd_Smed_v6_9904_0_1, dd_Smed_v6_9904_0_1, [RH, Score=359, Expect=5e-110]} {RNA1509_3073} {RNA1310_3165.1, RNA1509_3073} {RNA1509_3073, RNA815_1390}

Mlig455_018617 {REF} {Length: 1059} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=47.3]} {Human: ENSG00000089060, SLC8B1, solute carrier family 8 member B1, [Score=97.1, Expect=4e-25]} {Mouse: ENSMUSG00000032754, Slc8b1, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1, [Score=95.1, Expect=3e-23]} {Dmel: FBgn0033599, CG13223, [Score=60.5, Expect=3e-11]} {Celegans: WBGene00003572, ncx-7, Putative sodium/calcium exchanger 7, [Score=68.9, Expect=3e-14]} {Smed: dd_Smed_v6_20334_0_5, dd_Smed_v6_20334_0_5, [Score=114, Expect=6e-33]} {RNA1509_3073} {RNA1310_3165.1} {RNA815_1823}
17. MligTC455_41352 1305 27.18 Mlig455_037071

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.918/0.00007
Region-enriched R3: 1.036/0.03342

MOGAT2 2.489 - - - 0.951 0.825 0.713 Mlig455_037071 {REF} {Length: 866} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=209.7]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [Score=189, Expect=9e-60]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [Score=184, Expect=8e-57]} {Dmel: FBgn0033215, CG1942, [Score=154, Expect=4e-45]} {Celegans: WBGene00019464, K07B1.4, [Score=172, Expect=3e-52]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [Score=154, Expect=1e-45]} {RNA1509_20138} {RNA1310_22626} {RNA815_11687.1}
18. MligTC455_40294 928 19.33 Mlig455_062769

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.415

Region-enriched R4: 2.693/0.00000
Region-enriched R3: 1.531/0.00694
Region-enriched R5: 1.366/0.00671

VAV1 2.484 - - - 0.965 0.751 0.768 Mlig455_062769 {REF} {Length: 4319} {Pfam: SH2 domain [PF00017.26, score=34.9]; RhoGEF domain [PF00621.22, score=28.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.1]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=93.6, Expect=5e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=91.3, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=61.2, Expect=2e-09]} {Celegans: WBGene00006887, vav-1, [Score=64.3, Expect=2e-10]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
19. MligTC455_26167 4416 92 Mlig455_001635

Neo: -

Age: -

Region-enriched R3: 1.339/0.03044

TUBB2B 2.477 - 0.723 0.788 0.966 - - Mlig455_001635 {REF} {Length: 2122} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=239.0]; Tubulin C-terminal domain [PF03953.19, score=140.8]; Misato Segment II tubulin-like domain [PF10644.11, score=23.2]} {Human: ENSG00000137285, TUBB2B, tubulin beta 2B class IIb, [Score=814, Expect=0.0]; ENSG00000137267, TUBB2A, tubulin beta 2A class IIa, [Score=812, Expect=0.0]; ENSG00000196230, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000227739, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000235067, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232421, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000224156, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000229684, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000183311, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000232575, TUBB, tubulin beta class I, [Score=811, Expect=0.0]; ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [Score=811, Expect=0.0]; ENSG00000258947, TUBB3, tubulin beta 3 class III, [Score=803, Expect=0.0]; ENSG00000104833, TUBB4A, tubulin beta 4A class IVa, [Score=802, Expect=0.0]; ENSG00000176014, TUBB6, tubulin beta 6 class V, [Score=784, Expect=0.0]; ENSG00000261456, TUBB8, tubulin beta 8 class VIII, [Score=775, Expect=0.0]} {Mouse: ENSMUSG00000001473, Tubb6, tubulin, beta 6 class V, [RH, Score=788, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [Score=773, Expect=0.0]} {Celegans: WBGene00006537, tbb-2, Tubulin beta-2 chain, [Score=781, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [Score=817, Expect=0.0]} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1310_13968.2, RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016} {RNA1509_15718, RNA1509_19379, RNA1509_19747, RNA1509_30988, RNA1509_36839, RNA1509_41622, RNA1509_5016, RNA815_1610.4}
20. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 2.454 - 0.713 - 0.963 - 0.778

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
21. MligTC455_38362 1015 21.16 Mlig455_045508

Neo: -

Age: -

Region-enriched R4: 1.693/0.01745
Region-enriched R5: 1.163/0.02906

AADAC 2.443 - - - 0.956 0.728 0.759 Mlig455_045508 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=113.1]; Carboxylesterase family [PF00135.30, score=19.9]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=96.3, Expect=2e-21]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=102, Expect=1e-23]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=98.2, Expect=3e-22]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=98.2, Expect=2e-22]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=82.0, Expect=5e-17]} {RNA1509_14307} {RNA1310_15560.2} {RNA815_8354}
22. MligTC455_40293 973 20.27 Mlig455_003116

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.598

Region-enriched R4: 2.611/0.00000
Region-enriched R3: 1.603/0.00240
Region-enriched R5: 1.400/0.00374

VAV1 2.44 - - - 0.961 0.734 0.745 Mlig455_003116 {REF} {Length: 5727} {Pfam: SH2 domain [PF00017.26, score=32.8]; RhoGEF domain [PF00621.22, score=31.4]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.4]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=95.1, Expect=2e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=92.0, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=65.1, Expect=2e-10]} {Celegans: WBGene00006887, vav-1, [Score=65.5, Expect=9e-11]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
23. MligTC455_39889 2060 42.92 Mlig455_033747

Neo: -

Age: -

GDPD1 2.439 - - - 0.979 0.703 0.757 Mlig455_033747 {REF} {Length: 1632} {Pfam: Glycerophosphoryl diester phosphodiesterase family [PF03009.19, score=130.1]} {Human: ENSG00000153982, GDPD1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=57.4, Expect=4e-09]} {Mouse: ENSMUSG00000061666, Gdpd1, glycerophosphodiester phosphodiesterase domain containing 1, [Score=55.1, Expect=4e-08]} {Celegans: WBGene00021497, Y40C5A.4, [RH, Score=53.9, Expect=5e-08]} {RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1310_11037, RNA1509_4963, RNA1509_55034, RNA1509_9150} {RNA1509_4963, RNA1509_55034, RNA1509_9150, RNA815_4734}
24. MligTC455_44360 1025 21.36 Mlig455_040098

Neo: -

Age: Down-Up-Up

Region-enriched R5: 1.368/0.00046

MTHFS 1.881 - - - 0.962 - 0.919 Mlig455_040098 {REF} {Length: 780} {TRANSSPLICED} {Pfam: 5-formyltetrahydrofolate cyclo-ligase family [PF01812.22, score=143.7]} {Human: ENSG00000136371, MTHFS, methenyltetrahydrofolate synthetase, [RH, Score=166, Expect=1e-51]} {Mouse: ENSMUSG00000066442, Mthfs, 5, 10-methenyltetrahydrofolate synthetase, [RH, Score=172, Expect=2e-54]; ENSMUSG00000079427, Mthfsl, 5, 10-methenyltetrahydrofolate synthetase-like, [RH, Score=170, Expect=2e-53]} {Dmel: FBgn0085453, CG34424, [RH, Score=140, Expect=1e-41]} {Celegans: WBGene00013708, Y106G6E.4, Probable 5-formyltetrahydrofolate cyclo-ligase, [RH, Score=131, Expect=3e-38]} {Smed: dd_Smed_v6_6292_0_1, dd_Smed_v6_6292_0_1, [RH, Score=158, Expect=4e-49]} {RNA1509_10860} {RNA1310_32695, RNA1509_10860} {RNA1509_10860, RNA815_23808}
25. MligTC455_14550 82 1.72 Mlig455_016928

Neo: -

Age: Down-Up-Up

Region-enriched R4: 4.810/0.01442

GRASP 1.835 - - - 0.993 - 0.842 Mlig455_016928 {REF} {Length: 1233} {Pfam: PDZ domain [PF17820.3, score=33.1]; PDZ domain [PF00595.26, score=25.0]} {Human: ENSG00000161835, GRASP, general receptor for phosphoinositides 1 associated scaffold protein, [RH, Score=55.8, Expect=5e-09]} {Mouse: ENSMUSG00000000531, Grasp, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, [RH, Score=58.5, Expect=5e-10]} {Dmel: FBgn0035676, ssp6, short spindle 6, [RH, Score=87.8, Expect=3e-20]} {Celegans: WBGene00009272, gras-1, GRASP (General Receptor for phosphoinositides 1-Associated Scaffold Protein) homolog, [RH, Score=64.7, Expect=9e-13]} {RNA1509_57284} {RNA1310_36717} {RNA815_20577}
26. MligTC455_45384 708 14.76 Mlig455_020701, Mlig455_020769

Neo: -

Age: Down-Down-Up

SUGCT 1.831 - - - 0.951 - 0.880

Mlig455_020701 {REF} {Length: 2068} {Pfam: CoA-transferase family III [PF02515.19, score=362.0]} {Human: ENSG00000175600, SUGCT, succinyl-CoA:glutarate-CoA transferase, [Score=370, Expect=8e-126]} {Mouse: ENSMUSG00000055137, Sugct, succinyl-CoA glutarate-CoA transferase, [Score=366, Expect=3e-124]} {Dmel: FBgn0038804, CG10877, [Score=345, Expect=4e-116]} {Celegans: WBGene00014128, ZK892.4, CaiB/baiF CoA-transferase family protein ZK892.4, [Score=93.2, Expect=5e-21]} {Smed: dd_Smed_v6_9420_0_1, dd_Smed_v6_9420_0_1, [Score=332, Expect=5e-112]} {RNA1509_48074} {RNA1310_24642, RNA1509_48074}

Mlig455_020769 {REF} {Length: 1733} {TRANSSPLICED} {Pfam: CoA-transferase family III [PF02515.19, score=104.7]} {Human: ENSG00000175600, SUGCT, succinyl-CoA:glutarate-CoA transferase, [Score=147, Expect=7e-39]} {Mouse: ENSMUSG00000055137, Sugct, succinyl-CoA glutarate-CoA transferase, [Score=149, Expect=2e-39]} {Dmel: FBgn0038804, CG10877, [Score=148, Expect=5e-39]} {Smed: dd_Smed_v6_9420_0_1, dd_Smed_v6_9420_0_1, [Score=125, Expect=2e-31]} {RNA1509_53402} {RNA1310_49818, RNA1509_53402}
27. MligTC455_51925 253 5.27 Mlig455_009245

Neo: -

Age: Down-Up-Down

Region-enriched R5: 1.320/0.02123

UGCG 1.808 - - - 0.965 - 0.843 Mlig455_009245 {REF} {Length: 3283} {Pfam: Glycosyl transferase family 21 [PF13506.8, score=148.2]; Glycosyltransferase like family 2 [PF13641.8, score=73.9]; Glycosyl transferase family group 2 [PF13632.8, score=41.9]} {Human: ENSG00000148154, UGCG, UDP-glucose ceramide glucosyltransferase, [Score=301, Expect=5e-99]} {Mouse: ENSMUSG00000028381, Ugcg, UDP-glucose ceramide glucosyltransferase, [Score=306, Expect=4e-101]} {Dmel: FBgn0067102, GlcT-1, Ceramide glucosyltransferase, [Score=317, Expect=1e-104]} {Celegans: WBGene00019127, cgt-3, Ceramide glucosyltransferase 3, [RH, Score=293, Expect=4e-95]} {Smed: dd_Smed_v6_2757_0_1, dd_Smed_v6_2757_0_1, [RH, Score=291, Expect=1e-94]} {RNA1509_16764, RNA1509_43390} {RNA1310_8682.2, RNA1509_16764, RNA1509_43390} {RNA1509_16764, RNA1509_43390, RNA815_2800}
28. MligTC455_16462 248 5.17 Mlig455_058597

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.200/0.02502
Region-enriched R3: 2.087/0.02407
Region-enriched R5: 1.741/0.03183

1.791 - - - 0.966 - 0.825 Mlig455_058597 {REF} {Length: 2499} {RNA1509_26769, RNA1509_36389, RNA1509_43355} {RNA1310_44087, RNA1509_26769, RNA1509_36389, RNA1509_43355} {RNA1509_26769, RNA1509_36389, RNA1509_43355, RNA815_22536}
29. MligTC455_36668 52 1.08 Mlig455_020415

Neo: -

Age: -

1.77 - - - 0.963 - 0.807 Mlig455_020415 {REF} {Length: 1590} {RNA1310_29239.3} {RNA815_18923}
30. MligTC455_35246 7311 152.31 Mlig455_042511

Neo: -

Age: -

Region-enriched R5: 1.083/0.00029

1.768 - - - - 0.953 0.815 Mlig455_042511 {REF} {Length: 4543} {TRANSSPLICED} {RNA1509_10463, RNA1509_11377, RNA1509_17314, RNA1509_22196, RNA1509_2366, RNA1509_25228, RNA1509_35727, RNA1509_46010, RNA1509_55844, RNA1509_60045} {RNA1310_8239, RNA1509_10463, RNA1509_11377, RNA1509_17314, RNA1509_22196, RNA1509_2366, RNA1509_25228, RNA1509_35727, RNA1509_46010, RNA1509_55844, RNA1509_60045} {RNA1509_10463, RNA1509_11377, RNA1509_17314, RNA1509_22196, RNA1509_2366, RNA1509_25228, RNA1509_35727, RNA1509_46010, RNA1509_55844, RNA1509_60045, RNA815_6648.1}
31. MligTC455_36226 789 16.43 Mlig455_028917

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.621

1.765 - - - 0.951 - 0.814 Mlig455_028917 {REF} {Length: 6194} {RNA1509_4302} {RNA1310_558} {RNA815_13710}
32. MligTC455_43406 1382 28.79 Mlig455_063546

Neo: -

Age: logFC(26M/2M)=-0.363

Region-enriched R4: 1.356/0.01589
Region-enriched R3: 1.139/0.04629

TRPA1 1.757 - - - 0.951 0.806 - Mlig455_063546 {REF} {Length: 5889} {Pfam: Ion transport protein [PF00520.33, score=52.1]; Ankyrin repeat [PF00023.32, score=19.5]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=130, Expect=7e-30]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=127, Expect=5e-29]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=139, Expect=6e-33]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=153, Expect=2e-37]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [Score=132, Expect=7e-31]} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA1509_46763} {RNA1310_1768.1, RNA1509_21433, RNA1509_40381, RNA1509_43070} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA815_3153}
33. MligTC455_08087 293 6.1 Mlig455_047522

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-2.126

Region-enriched R5: 1.898/0.04713

1.756 - - - 0.963 - 0.793 Mlig455_047522 {REF} {Length: 465} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_33866} {RNA1310_107768, RNA1509_33866} {RNA1509_33866, RNA815_62931}
34. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 1.749 - - - 0.951 - 0.798 Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
35. MligTC455_52450 1579 32.89 Mlig455_000119

Neo: -

Age: logFC(26M/2M)=0.275

Region-enriched R4: 1.401/0.02633

1.744 - - - 0.950 0.794 - Mlig455_000119 {REF} {Length: 2142} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=70.3]} {RNA1509_1907, RNA1509_19429, RNA1509_6458} {RNA1310_12956, RNA1509_19429, RNA1509_6458} {RNA1509_19429, RNA1509_6458, RNA815_4763}
36. MligTC455_48226 475 9.89 Mlig455_006039

Neo: -

Age: logFC(26M/2M)=0.772

Region-enriched R4: 2.063/0.02194
Region-enriched R3: 1.959/0.00629

1.733 - - - 0.950 0.783 - Mlig455_006039 {REF} {Length: 3886} {Celegans: WBGene00014141, ZK899.2, [RH, Score=145, Expect=5e-39]} {Smed: dd_Smed_v6_3689_0_1, dd_Smed_v6_3689_0_1, [RH, Score=360, Expect=2e-122]} {RNA1509_34003, RNA1509_40119, RNA1509_42065} {RNA1310_14532, RNA1509_34003, RNA1509_40119, RNA1509_42065} {RNA1509_34003, RNA1509_40119, RNA1509_42065, RNA815_4158}
37. MligTC455_53923 413 8.6 Mlig455_031505

Neo: -

Age: -

Region-enriched R3: 2.700/0.00511

MGAM 1.733 - - - 0.956 - 0.777 Mlig455_031505 {REF} {Length: 3805} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=338.5]} {Human: ENSG00000282607, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=363, Expect=4e-110]; ENSG00000090402, SI, sucrase-isomaltase, [Score=359, Expect=6e-109]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]; ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=347, Expect=9e-105]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=361, Expect=6e-112]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=353, Expect=4e-107]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=150, Expect=6e-38]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [Score=364, Expect=3e-115]} {Smed: dd_Smed_v6_4668_0_1, dd_Smed_v6_4668_0_1, [Score=333, Expect=6e-104]} {RNA1509_3169} {RNA1310_1135} {RNA815_4014}
38. MligTC455_24085 1786 37.2 Mlig455_007320

Neo: -

Age: logFC(26M/2M)=0.210

Region-enriched R3: 2.481/0.00000
Region-enriched R5: 1.136/0.04856

ACHE 1.727 - - - 0.952 0.775 - Mlig455_007320 {REF} {Length: 2268} {Pfam: Carboxylesterase family [PF00135.30, score=353.8]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=232, Expect=2e-67]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=227, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=202, Expect=2e-56]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=223, Expect=2e-64]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=206, Expect=5e-58]} {RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1310_10437.1, RNA1509_28908, RNA1509_31228, RNA1509_46106} {RNA1509_28908, RNA1509_31228, RNA1509_46106, RNA815_3976}
39. MligTC455_28707 1065 22.19 Mlig455_033092

Neo: -

Age: logFC(26M/2M)=0.629

Region-enriched R4: 2.478/0.00050
Region-enriched R3: 1.976/0.00423

1.725 - - - 0.960 0.765 - Mlig455_033092 {REF} {Length: 2843} {Pfam: SH2 domain [PF00017.26, score=18.7]} {RNA1509_4794} {RNA1310_7767.1} {RNA815_2526}
40. MligTC455_26913 1252 26.09 Mlig455_035418

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=2.504

Region-enriched R3: 1.751/0.00053
Region-enriched R4: 1.310/0.04608

1.722 - - - 0.950 0.772 - Mlig455_035418 {REF} {Length: 4935} {Pfam: Fibronectin type III domain [PF00041.23, score=99.3]} {Mouse: ENSMUSG00000026193, Fn1, fibronectin 1, [Score=53.1, Expect=1e-06]} {RNA1509_5914, RNA1509_59574} {RNA1310_11509.1, RNA1509_59574} {RNA1509_59574, RNA815_4107}
41. MligTC455_41895 2935 61.14 Mlig455_023418, Mlig455_023445

Neo: -

Age: logFC(26M/2M)=0.336

Region-enriched R5: 1.564/0.00001

SERPINB9 1.717 - - - - 0.951 0.766

Mlig455_023418 {REF} {Length: 2465} {TRANSSPLICED} {Pfam: Serpin (serine protease inhibitor) [PF00079.22, score=269.5]} {Human: ENSG00000170542, SERPINB9, serpin family B member 9, [Score=152, Expect=6e-42]; ENSG00000166401, SERPINB8, serpin family B member 8, [Score=149, Expect=1e-40]; ENSG00000197632, SERPINB2, serpin family B member 2, [Score=146, Expect=2e-39]} {Mouse: ENSMUSG00000079049, Serpinb1c, serine (or cysteine) peptidase inhibitor, clade B, member 1c, [Score=151, Expect=6e-42]; ENSMUSG00000045827, Serpinb9, serine (or cysteine) peptidase inhibitor, clade B, member 9, [Score=148, Expect=1e-40]; ENSMUSG00000047889, Serpinb6d, serine (or cysteine) peptidase inhibitor, clade B, member 6d, [Score=147, Expect=2e-40]; ENSMUSG00000042842, Serpinb6b, serine (or cysteine) peptidase inhibitor, clade B, member 6b, [Score=147, Expect=2e-40]; ENSMUSG00000058017, Serpinb3d, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D, [Score=144, Expect=5e-39]; ENSMUSG00000052180, Serpinb6c, serine (or cysteine) peptidase inhibitor, clade B, member 6c, [Score=144, Expect=3e-39]; ENSMUSG00000073602, Serpinb3b, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B, [Score=144, Expect=5e-39]} {Dmel: FBgn0028983, Spn55B, Serpin 55B, [Score=137, Expect=1e-36]} {Celegans: WBGene00005648, srp-7, SeRPin; Serine or cysteine protease inhibitor, [Score=120, Expect=8e-31]} {Smed: dd_Smed_v6_1741_0_1, dd_Smed_v6_1741_0_1, [Score=140, Expect=5e-38]} {RNA1509_7122} {RNA1310_6171.1} {RNA815_3542}

Mlig455_023445 {REF} {Length: 2290} {TRANSSPLICED} {Pfam: Serpin (serine protease inhibitor) [PF00079.22, score=275.0]} {Human: ENSG00000170542, SERPINB9, serpin family B member 9, [Score=158, Expect=4e-44]; ENSG00000166401, SERPINB8, serpin family B member 8, [Score=153, Expect=4e-42]; ENSG00000197632, SERPINB2, serpin family B member 2, [Score=152, Expect=2e-41]} {Mouse: ENSMUSG00000079049, Serpinb1c, serine (or cysteine) peptidase inhibitor, clade B, member 1c, [Score=155, Expect=2e-43]; ENSMUSG00000045827, Serpinb9, serine (or cysteine) peptidase inhibitor, clade B, member 9, [Score=155, Expect=6e-43]; ENSMUSG00000058017, Serpinb3d, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D, [Score=151, Expect=1e-41]; ENSMUSG00000042842, Serpinb6b, serine (or cysteine) peptidase inhibitor, clade B, member 6b, [Score=151, Expect=1e-41]; ENSMUSG00000052180, Serpinb6c, serine (or cysteine) peptidase inhibitor, clade B, member 6c, [Score=149, Expect=6e-41]; ENSMUSG00000073602, Serpinb3b, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B, [Score=149, Expect=8e-41]; ENSMUSG00000026715, Serpinc1, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1, [Score=149, Expect=7e-40]} {Dmel: FBgn0028983, Spn55B, Serpin 55B, [Score=138, Expect=6e-37]} {Celegans: WBGene00005648, srp-7, SeRPin; Serine or cysteine protease inhibitor, [Score=119, Expect=6e-30]} {Smed: dd_Smed_v6_3824_0_1, dd_Smed_v6_3824_0_1, [Score=152, Expect=3e-42]} {RNA1509_3621, RNA1509_7122} {RNA1310_6171.1, RNA1509_3621, RNA1509_7122} {RNA1509_3621, RNA1509_7122, RNA815_3542}
42. MligTC455_23305 524 10.91 Mlig455_054093

Neo: -

Age: -

Region-enriched R3: 1.848/0.00073
Region-enriched R4: 1.814/0.00794

CH25H 1.716 - - - 0.959 - 0.757 Mlig455_054093 {REF} {Length: 2052} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=77.6]} {Human: ENSG00000138135, CH25H, cholesterol 25-hydroxylase, [RH, Score=168, Expect=7e-50]} {Mouse: ENSMUSG00000050370, Ch25h, cholesterol 25-hydroxylase, [RH, Score=182, Expect=3e-55]} {Celegans: WBGene00018036, F35C8.5, Cholesterol 25-hydroxylase-like protein, [RH, Score=199, Expect=6e-62]} {RNA1509_13990, RNA1509_16293, RNA1509_2104} {RNA1310_8947, RNA1509_13990, RNA1509_16293, RNA1509_2104} {RNA1509_13990, RNA1509_16293, RNA1509_2104, RNA815_835.1}
43. MligTC455_31181 3530 73.55 Mlig455_051856, Mlig455_051892

Neo: -

Age: -

Region-enriched R6: 1.979/0.00019
Region-enriched R5: 1.598/0.00061
Region-enriched R3: 1.383/0.02407
Region-enriched R4: 1.335/0.03212

ANPEP, ERAP1 1.715 - - 0.950 - 0.765 -

Mlig455_051856 {REF} {Length: 5257} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=263.7]; Peptidase family M1 domain [PF01433.22, score=247.0]; Peptidase M1 N-terminal domain [PF17900.3, score=143.0]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [RH, Score=578, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=565, Expect=0.0]} {Dmel: FBgn0039640, CG14516, [RH, Score=545, Expect=4e-178]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [RH, Score=438, Expect=9e-138]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [RH, Score=644, Expect=0.0]} {RNA1509_14294, RNA1509_1573, RNA1509_20439} {RNA1310_1662.1, RNA1509_14294, RNA1509_20439} {RNA1509_14294, RNA1509_20439, RNA815_486.1}

Mlig455_051892 {REF} {Length: 3530} {Pfam: Peptidase family M1 domain [PF01433.22, score=52.4]; ERAP1-like C-terminal domain [PF11838.10, score=39.9]; FimH, mannose binding [PF09160.12, score=18.4]} {Human: ENSG00000164307, ERAP1, endoplasmic reticulum aminopeptidase 1, [Score=108, Expect=5e-26]; ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=105, Expect=3e-25]} {Mouse: ENSMUSG00000021583, Erap1, endoplasmic reticulum aminopeptidase 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0039656, CG11951, [Score=92.0, Expect=9e-21]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=100, Expect=7e-24]} {Smed: dd_Smed_v6_1249_0_1, dd_Smed_v6_1249_0_1, [Score=95.9, Expect=2e-22]} {RNA1509_13872} {RNA1310_1662.1} {RNA815_3255}
44. MligTC455_48070 1559 32.49 Mlig455_019661

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R3: 1.615/0.01457

HSD11B1 1.712 - - - 0.956 - 0.756 Mlig455_019661 {REF} {Length: 1828} {Pfam: short chain dehydrogenase [PF00106.27, score=125.5]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.3]; KR domain [PF08659.12, score=27.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=157, Expect=2e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=154, Expect=1e-44]} {Dmel: FBgn0027583, CG7601, [Score=82.0, Expect=1e-17]} {Celegans: WBGene00014093, ZK829.1, [Score=74.3, Expect=4e-15]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=62.8, Expect=2e-11]} {RNA1509_11335, RNA1509_15148} {RNA1310_26648, RNA1509_11335, RNA1509_15148} {RNA1509_11335, RNA1509_15148, RNA815_11342}
45. MligTC455_53924 345 7.18 Mlig455_031500, Mlig455_031504

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.512/0.02739

MGAM, MGAM2 1.696 - - - 0.955 - 0.741

Mlig455_031500 {REF} {Length: 6467} {TRANSSPLICED} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=771.4]; N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase [PF16863.7, score=128.0]; Trefoil (P-type) domain [PF00088.20, score=47.5]; Galactose mutarotase-like [PF13802.8, score=46.7]} {Human: ENSG00000282607, MGAM, maltase-glucoamylase, [RH, Score=969, Expect=0.0]; ENSG00000257335, MGAM, maltase-glucoamylase, [RH, Score=969, Expect=0.0]; ENSG00000090402, SI, sucrase-isomaltase, [RH, Score=942, Expect=0.0]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [RH, Score=969, Expect=0.0]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [RH, Score=952, Expect=0.0]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=188, Expect=3e-48]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [RH, Score=482, Expect=4e-147]} {Smed: dd_Smed_v6_1062_0_1, dd_Smed_v6_1062_0_1, [Score=466, Expect=1e-142]} {RNA1509_3169} {RNA1310_1135} {RNA815_4014}

Mlig455_031504 {REF} {Length: 414} {Human: ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=71.6, Expect=6e-15]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=71.6, Expect=6e-15]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=70.1, Expect=2e-14]; ENSG00000282607, MGAM, maltase-glucoamylase, [Score=69.7, Expect=3e-14]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=68.2, Expect=7e-14]} {Celegans: WBGene00019895, aagr-2, Acid Alpha Glucosidase Relate, [Score=73.9, Expect=3e-16]} {Smed: dd_Smed_v6_1062_0_2, dd_Smed_v6_1062_0_2, [Score=58.5, Expect=6e-11]} {RNA1509_3169} {RNA1310_1135} {RNA815_943}
46. MligTC455_07347 70 1.47 Mlig455_065785, Mlig455_065805

Neo: -

Age: -

Region-enriched R4: 6.487/0.00059

FLVCR1, FLVCR2 1.694 - - - 0.952 - 0.742

Mlig455_065785 {REF} {Length: 1658} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=105.8]; Sugar (and other) transporter [PF00083.26, score=28.4]} {Human: ENSG00000162769, FLVCR1, feline leukemia virus subgroup C cellular receptor 1, [RH, Score=340, Expect=4e-111]} {Mouse: ENSMUSG00000034258, Flvcr2, feline leukemia virus subgroup C cellular receptor 2, [RH, Score=359, Expect=1e-118]} {Dmel: FBgn0033196, CG1358, [RH, Score=366, Expect=3e-122]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [RH, Score=372, Expect=1e-123]} {Smed: dd_Smed_v6_7578_0_1, dd_Smed_v6_7578_0_1, [RH, Score=361, Expect=1e-120]} {RNA1310_13875} {RNA815_15816}

Mlig455_065805 {REF} {Length: 1618} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=103.3]; Sugar (and other) transporter [PF00083.26, score=30.5]} {Human: ENSG00000119686, FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2, [Score=317, Expect=2e-102]; ENSG00000162769, FLVCR1, feline leukemia virus subgroup C cellular receptor 1, [Score=315, Expect=2e-101]} {Mouse: ENSMUSG00000034258, Flvcr2, feline leukemia virus subgroup C cellular receptor 2, [Score=328, Expect=9e-107]} {Dmel: FBgn0033196, CG1358, [Score=331, Expect=8e-109]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [Score=342, Expect=2e-113]} {Smed: dd_Smed_v6_7578_0_1, dd_Smed_v6_7578_0_1, [Score=330, Expect=9e-109]} {RNA1310_13875} {RNA815_15816}
47. MligTC455_20134 584 12.17 Mlig455_039542

Neo: -

Age: Down-Down-Up

ATP1B2 1.694 - - - 0.974 - 0.720 Mlig455_039542 {REF} {Length: 1390} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=192.1]} {Human: ENSG00000129244, ATP1B2, ATPase Na+/K+ transporting subunit beta 2, [Score=101, Expect=5e-24]; ENSG00000101892, ATP1B4, ATPase Na+/K+ transporting family member beta 4, [Score=96.7, Expect=6e-22]} {Mouse: ENSMUSG00000041329, Atp1b2, ATPase, Na+/K+ transporting, beta 2 polypeptide, [Score=101, Expect=4e-24]; ENSMUSG00000032412, Atp1b3, ATPase, Na+/K+ transporting, beta 3 polypeptide, [Score=96.7, Expect=1e-22]} {Dmel: FBgn0015777, nrv2, nervana 2, [Score=145, Expect=2e-40]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=1e-42]} {Smed: dd_Smed_v6_2230_0_4, dd_Smed_v6_2230_0_4, [RH, Score=213, Expect=7e-67]} {RNA1509_2976, RNA1509_59487} {RNA1310_26809, RNA1509_2976, RNA1509_59487} {RNA1509_2976, RNA1509_59487, RNA815_11848}
48. MligTC455_09840 420 8.75 Mlig455_050348, Mlig455_050362

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-2.191

BCO2 1.674 - - - 0.954 - 0.720

Mlig455_050348 {REF} {Length: 3061} {Pfam: Retinal pigment epithelial membrane protein [PF03055.17, score=236.4]} {Human: ENSG00000197580, BCO2, beta-carotene oxygenase 2, [Score=110, Expect=2e-25]; ENSG00000135697, BCO1, beta-carotene oxygenase 1, [Score=106, Expect=9e-24]} {Mouse: ENSMUSG00000032066, Bco2, beta-carotene oxygenase 2, [Score=97.8, Expect=4e-21]; ENSMUSG00000028174, Rpe65, retinal pigment epithelium 65, [Score=97.1, Expect=7e-21]; ENSMUSG00000031845, Bco1, beta-carotene oxygenase 1, [Score=95.5, Expect=3e-20]} {Smed: dd_Smed_v6_4523_0_1, dd_Smed_v6_4523_0_1, [Score=67.4, Expect=9e-12]} {RNA1509_30736} {RNA1310_9061, RNA1509_30736} {RNA1509_30736, RNA815_3886}

Mlig455_050362 {REF} {Length: 2942} {Pfam: Retinal pigment epithelial membrane protein [PF03055.17, score=236.4]} {Human: ENSG00000197580, BCO2, beta-carotene oxygenase 2, [Score=110, Expect=2e-25]; ENSG00000135697, BCO1, beta-carotene oxygenase 1, [Score=106, Expect=9e-24]} {Mouse: ENSMUSG00000032066, Bco2, beta-carotene oxygenase 2, [Score=97.8, Expect=4e-21]; ENSMUSG00000028174, Rpe65, retinal pigment epithelium 65, [Score=97.1, Expect=7e-21]; ENSMUSG00000031845, Bco1, beta-carotene oxygenase 1, [Score=95.5, Expect=3e-20]} {Smed: dd_Smed_v6_4523_0_1, dd_Smed_v6_4523_0_1, [Score=67.4, Expect=9e-12]} {RNA1509_30736} {RNA1310_9061} {RNA815_3886}
49. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 1.674 - - - 0.956 0.718 - Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
50. MligTC455_26178 362 7.54 Mlig455_016066

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.817

Region-enriched R4: 2.312/0.03652
Region-enriched R3: 2.220/0.04325

1.67 - - - 0.963 0.707 - Mlig455_016066 {REF} {Length: 1028} {RNA1509_21892} {RNA1310_19861} {RNA815_9448.1}
51. MligTC455_16927 164 3.42 Mlig455_049788

Neo: -

Age: Down-Down-Up

Region-enriched R5: 1.406/0.02662

HBS1L 0.977 - - - - - 0.977 Mlig455_049788 {REF} {Length: 2488} {TRANSSPLICED} {Pfam: Elongation factor Tu GTP binding domain [PF00009.29, score=148.0]; Uncharacterised protein family UPF0047 [PF01894.19, score=124.0]; Elongation factor Tu C-terminal domain [PF03143.19, score=53.4]; 50S ribosome-binding GTPase [PF01926.25, score=25.3]} {Human: ENSG00000112339, HBS1L, HBS1 like translational GTPase, [RH, Score=441, Expect=2e-145]} {Mouse: ENSMUSG00000019977, Hbs1l, Hbs1-like (S. cerevisiae), [RH, Score=405, Expect=3e-131]} {Dmel: FBgn0042712, HBS1, [RH, Score=414, Expect=7e-135]} {Celegans: WBGene00010622, K07A12.4, [RH, Score=337, Expect=3e-106]} {Smed: dd_Smed_v6_9327_0_1, dd_Smed_v6_9327_0_1, [RH, Score=397, Expect=3e-129]} {RNA1509_18150} {RNA1310_11738} {RNA815_5048.1}
52. MligTC455_31180 2635 54.89 Mlig455_051867

Neo: -

Age: logFC(26M/2M)=0.298

Region-enriched R6: 1.875/0.00081
Region-enriched R5: 1.564/0.00104
Region-enriched R4: 1.318/0.04234

ANPEP 0.975 - - 0.975 - - - Mlig455_051867 {REF} {Length: 4944} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=264.9]; Peptidase family M1 domain [PF01433.22, score=166.1]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=377, Expect=2e-118]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=384, Expect=3e-121]} {Dmel: FBgn0052473, CG32473, [Score=344, Expect=7e-107]} {Celegans: WBGene00009865, F49B2.6, Aminopeptidase, [Score=282, Expect=7e-83]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=393, Expect=2e-124]} {RNA1509_1573} {RNA1310_1662.1, RNA1509_1573} {RNA1509_1573, RNA815_759.1}
53. MligTC455_42219 322 6.7 Mlig455_050268

Neo: Irradiation

Age: Up-Down-Down

Region-specific R4: 3.812

Region-enriched R4: 2.572/0.00001

SLC51A 0.97 - - - 0.970 - - Mlig455_050268 {REF} {Length: 3212} {Pfam: Organic solute transporter Ostalpha [PF03619.18, score=109.5]} {Human: ENSG00000163959, SLC51A, solute carrier family 51 alpha subunit, [RH, Score=57.0, Expect=1e-08]} {Mouse: ENSMUSG00000035699, Slc51a, solute carrier family 51, alpha subunit, [RH, Score=61.6, Expect=3e-10]} {Celegans: WBGene00012182, osta-3, Organic solute transporter alpha-like protein 3, [RH, Score=96.3, Expect=2e-22]} {RNA1509_16927} {RNA1310_16316} {RNA815_9480.1}
54. MligTC455_08029 56 1.17 Mlig455_005478

Neo: -

Age: -

0.969 - - - 0.969 - - Mlig455_005478 {REF} {Length: 968} {NoTransDecoderORF} {RNA1310_138835}
55. MligTC455_18949 278 5.8 Mlig455_066715

Neo: -

Age: -

METTL8 0.969 - - - - - 0.969 Mlig455_066715 {REF} {Length: 2927} {Pfam: Methyltransferase domain [PF13489.8, score=45.0]; Methyltransferase domain [PF13649.8, score=36.9]; Methyltransferase domain [PF08242.14, score=34.9]; Methyltransferase domain [PF08241.14, score=26.2]; Methyltransferase domain [PF13578.8, score=23.8]} {Human: ENSG00000123600, METTL8, methyltransferase like 8, [RH, Score=192, Expect=1e-57]; ENSG00000165055, METTL2B, methyltransferase like 2B, [RH, Score=192, Expect=1e-57]; ENSG00000087995, METTL2A, methyltransferase like 2A, [RH, Score=192, Expect=2e-58]} {Mouse: ENSMUSG00000041975, Mettl8, methyltransferase like 8, [RH, Score=194, Expect=2e-58]} {Dmel: FBgn0035247, metl, methyltransferase-like, [RH, Score=251, Expect=2e-81]} {Celegans: WBGene00044720, metl-2, MEthylTransferase Like, [RH, Score=243, Expect=2e-78]} {Smed: dd_Smed_v6_3413_0_1, dd_Smed_v6_3413_0_1, [RH, Score=258, Expect=7e-85]} {RNA1509_27927, RNA1509_6032} {RNA1310_26875, RNA1509_27927} {RNA1509_27927, RNA815_11503}
56. MligTC455_34547 437 9.11 Mlig455_052252

Neo: -

Age: -

Region-enriched R3: 2.304/0.02662

0.968 - - - 0.968 - - Mlig455_052252 {REF} {Length: 1475} {RNA1509_4906} {RNA1310_88.1} {RNA815_214}
57. MligTC455_34548 892 18.58 Mlig455_037149, Mlig455_052297

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.952/0.03060

0.968 - - - 0.968 - -

Mlig455_037149 {REF} {Length: 10460} {TRANSSPLICED} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=31.2]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=55.8, Expect=5e-07]} {RNA1509_40938, RNA1509_4906} {RNA1310_88.1, RNA1509_40938} {RNA1509_40938, RNA815_214}

Mlig455_052297 {REF} {Length: 9432} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=36.3]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=52.0, Expect=7e-06]} {RNA1509_4906} {RNA1310_88.1} {RNA815_214}
58. MligTC455_48919 343 7.14 Mlig455_004050

Neo: -

Age: logFC(26M/2M)=0.295

Region-enriched R3: 3.001/0.00120

AMY1C 0.968 - - - 0.968 - - Mlig455_004050 {REF} {Length: 4713} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=45.5]} {Human: ENSG00000187733, AMY1C, amylase, alpha 1C (salivary), [Score=442, Expect=2e-150]; ENSG00000237763, AMY1A, amylase, alpha 1A (salivary), [Score=442, Expect=2e-150]; ENSG00000174876, AMY1B, amylase, alpha 1B (salivary), [Score=442, Expect=2e-150]; ENSG00000243480, AMY2A, amylase, alpha 2A (pancreatic), [Score=441, Expect=6e-150]; ENSG00000240038, AMY2B, amylase, alpha 2B (pancreatic), [Score=440, Expect=7e-150]} {Mouse: ENSMUSG00000074264, Amy1, amylase 1, salivary, [Score=438, Expect=3e-149]; ENSMUSG00000096569, Amy2a2, amylase 2a2, [Score=430, Expect=3e-146]; ENSMUSG00000093931, Amy2a3, amylase 2a3, [Score=430, Expect=3e-146]; ENSMUSG00000074268, Amy2a5, amylase 2a5, [Score=430, Expect=3e-146]; ENSMUSG00000096770, Amy2a4, amylase 2a4, [Score=430, Expect=3e-146]} {Dmel: FBgn0000078, Amy-d, Amylase distal, [Score=377, Expect=7e-126]} {Celegans: WBGene00008220, C50B6.7, Alpha-amylase, [Score=318, Expect=2e-100]} {RNA1509_24944} {RNA1310_6099.1, RNA1509_24944} {RNA1509_24944, RNA815_5046}
59. MligTC455_18923 743 15.48 Mlig455_063038

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.791

Region-enriched R4: 2.273/0.01537

0.965 - - - 0.965 - - Mlig455_063038 {REF} {Length: 1906} {RNA1509_26120} {RNA1310_29982} {RNA815_3607}
60. MligTC455_37159 93 1.93 Mlig455_043051

Neo: -

Age: -

0.965 - - - - - 0.965 Mlig455_043051 {REF} {Length: 1890} {Pfam: Glycosyltransferase family 92 [PF01697.29, score=88.2]} {Dmel: FBgn0030443, CG12715, [RH, Score=99.8, Expect=4e-23]} {Smed: dd_Smed_v6_5401_0_1, dd_Smed_v6_5401_0_1, [Score=57.8, Expect=2e-09]} {RNA1509_44824} {RNA1310_15859} {RNA815_6722}
61. MligTC455_44699 2074 43.2 Mlig455_048395

Neo: -

Age: logFC(26M/2M)=0.553

Region-enriched R3: 1.711/0.00637

SLC10A5 0.964 - - - 0.964 - - Mlig455_048395 {REF} {Length: 1771} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=116.4]} {Human: ENSG00000253598, SLC10A5, solute carrier family 10 member 5, [RH, Score=130, Expect=9e-33]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=129, Expect=4e-33]; ENSMUSG00000058921, Slc10a5, solute carrier family 10 (sodium/bile acid cotransporter family), member 5, [Score=125, Expect=6e-31]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=9e-31]} {Dmel: FBgn0030756, CG9903, [Score=103, Expect=1e-23]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=206, Expect=4e-60]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [RH, Score=295, Expect=3e-95]} {RNA1509_51285} {RNA1310_359.1} {RNA815_3102}
62. MligTC455_05667 30 0.63 Mlig455_042902

Neo: -

Age: -

0.959 - - - 0.959 - - Mlig455_042902 {REF} {Length: 1134} {RNA1509_46896} {RNA1310_11786}
63. MligTC455_42765 49 1.03 Mlig455_055136

Neo: -

Age: logFC(26M/2M)=0.439

Region-enriched R5: 2.826/0.04177

AHNAK2 0.958 - - - 0.958 - - Mlig455_055136 {REF} {Length: 6053} {TRANSSPLICED} {Human: ENSG00000185567, AHNAK2, AHNAK nucleoprotein 2, [Score=68.2, Expect=2e-10]} {Mouse: ENSMUSG00000072812, Ahnak2, AHNAK nucleoprotein 2, [Score=51.2, Expect=1e-05]} {RNA1509_23810} {RNA1310_9986} {RNA815_12447.1}
64. MligTC455_47303 180 3.75 Mlig455_022918

Neo: -

Age: Down-Up-Down

ARHGAP24 0.957 - - - - - 0.957 Mlig455_022918 {REF} {Length: 2607} {TRANSSPLICED} {Pfam: RhoGAP domain [PF00620.29, score=35.9]} {Human: ENSG00000138639, ARHGAP24, Rho GTPase activating protein 24, [Score=72.4, Expect=9e-13]; ENSG00000128805, ARHGAP22, Rho GTPase activating protein 22, [Score=72.0, Expect=1e-12]; ENSG00000163219, ARHGAP25, Rho GTPase activating protein 25, [Score=70.9, Expect=3e-12]} {Mouse: ENSMUSG00000057315, Arhgap24, Rho GTPase activating protein 24, [Score=75.1, Expect=1e-13]} {Smed: dd_Smed_v6_6320_0_1, dd_Smed_v6_6320_0_1, [Score=70.1, Expect=1e-12]} {RNA1509_23863} {RNA1310_16225.1} {RNA815_11840}
65. MligTC455_17477 47 0.98 Mlig455_053346

Neo: -

Age: -

0.955 - - - 0.955 - - Mlig455_053346 {REF} {Length: 2041} {RNA1509_20382} {RNA1310_59327} {RNA815_58492}
66. MligTC455_25519 1173 24.43 Mlig455_012881

Neo: -

Age: logFC(26M/2M)=-0.253

Region-enriched R3: 1.409/0.00967

SLC13A3 0.955 - - - 0.955 - - Mlig455_012881 {REF} {Length: 4943} {Pfam: Sodium:sulfate symporter transmembrane region [PF00939.21, score=346.8]; Citrate transporter [PF03600.18, score=107.6]} {Human: ENSG00000158296, SLC13A3, solute carrier family 13 member 3, [Score=411, Expect=4e-135]; ENSG00000141485, SLC13A5, solute carrier family 13 member 5, [Score=410, Expect=6e-135]; ENSG00000007216, SLC13A2, solute carrier family 13 member 2, [Score=393, Expect=4e-128]} {Mouse: ENSMUSG00000001095, Slc13a2, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, [Score=402, Expect=6e-132]; ENSMUSG00000029700, Slc13a1, solute carrier family 13 (sodium/sulfate symporters), member 1, [Score=401, Expect=1e-131]; ENSMUSG00000018459, Slc13a3, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, [Score=386, Expect=1e-125]} {Dmel: FBgn0036816, Indy, I'm not dead yet, [Score=303, Expect=5e-94]} {Celegans: WBGene00003517, nac-1, Sodium-dependent low-affinity dicarboxylate transporter 1, [Score=334, Expect=4e-106]} {Smed: dd_Smed_v6_15654_0_1, dd_Smed_v6_15654_0_1, [Score=350, Expect=3e-112]} {RNA1509_17695, RNA1509_5950} {RNA1310_9467.1, RNA1509_17695, RNA1509_5950} {RNA1509_17695, RNA1509_5950, RNA815_3472}
67. MligTC455_49771 61 1.26 Mlig455_018423

Neo: -

Age: -

0.955 - - - 0.955 - - Mlig455_018423 {REF} {Length: 2813} {RNA1509_25822} {RNA1310_57791} {RNA815_29848}
68. MligTC455_11353 696 14.51 Mlig455_004383, Mlig455_037197

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 4.069

0.954 - - - 0.954 - -

Mlig455_004383 {REF} {Length: 3587} {RNA1509_23567} {RNA1310_21215} {RNA815_19894}

Mlig455_037197 {REF} {Length: 4232} {RNA1509_23567} {RNA1310_21215, RNA1509_23567} {RNA1509_23567, RNA815_19894}
69. MligTC455_19299 65 1.35 Mlig455_001048

Neo: -

Age: -

0.954 - - - 0.954 - - Mlig455_001048 {REF} {Length: 2071} {NoTransDecoderORF} {RNA1310_76604}
70. MligTC455_46685 74 1.55 Mlig455_053215

Neo: -

Age: logFC(26M/2M)=0.844

MAP3K19 0.953 - - - 0.953 - - Mlig455_053215 {REF} {Length: 2357} {Pfam: Protein kinase domain [PF00069.27, score=170.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=139.4]; Ankyrin repeats (many copies) [PF13637.8, score=35.8]; Ankyrin repeats (3 copies) [PF12796.9, score=34.1]; Fungal protein kinase [PF17667.3, score=26.9]; Ankyrin repeat [PF13606.8, score=22.2]; ABC1 atypical kinase-like domain [PF03109.18, score=20.8]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=147, Expect=3e-36]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=150, Expect=2e-37]} {Dmel: FBgn0035001, Slik, Sterile20-like kinase, [Score=140, Expect=2e-34]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=125, Expect=9e-30]} {Smed: dd_Smed_v6_2030_0_14, dd_Smed_v6_2030_0_14, [Score=131, Expect=4e-33]} {RNA1509_11461} {RNA1310_9478.1} {RNA815_3045}
71. MligTC455_33379 73 1.53 Mlig455_048175

Neo: -

Age: -

PDSS1 0.951 - - - - - 0.951 Mlig455_048175 {REF} {Length: 1712} {TRANSSPLICED} {Pfam: Polyprenyl synthetase [PF00348.19, score=196.4]} {Human: ENSG00000148459, PDSS1, decaprenyl diphosphate synthase subunit 1, [RH, Score=229, Expect=4e-71]} {Mouse: ENSMUSG00000026784, Pdss1, prenyl (solanesyl) diphosphate synthase, subunit 1, [RH, Score=226, Expect=3e-70]} {Dmel: FBgn0051005, qless, [RH, Score=235, Expect=9e-74]} {Celegans: WBGene00000761, coq-1, COenzyme Q (Ubiquinone) biosynthesis, [RH, Score=211, Expect=3e-65]} {Smed: dd_Smed_v6_12221_0_1, dd_Smed_v6_12221_0_1, [RH, Score=252, Expect=3e-81]} {RNA1509_18613} {RNA1310_15422} {RNA815_6758.1}
72. MligTC455_49766 1596 33.24 Mlig455_058625

Neo: -

Age: Down-Up-Up

Region-enriched R3: 1.734/0.00027
Region-enriched R4: 1.458/0.00884

PNP 0.951 - - - 0.951 - - Mlig455_058625 {REF} {Length: 1062} {Pfam: Phosphorylase superfamily [PF01048.22, score=101.3]} {Human: ENSG00000198805, PNP, purine nucleoside phosphorylase, [Score=205, Expect=1e-64]} {Mouse: ENSMUSG00000115338, Pnp, purine-nucleoside phosphorylase, [Score=195, Expect=5e-61]; ENSMUSG00000068417, Pnp2, purine-nucleoside phosphorylase 2, [Score=194, Expect=1e-60]} {Dmel: FBgn0035348, CG16758, [Score=191, Expect=2e-59]} {Celegans: WBGene00019298, K02D7.1, Purine nucleoside phosphorylase, [Score=169, Expect=4e-51]} {Smed: dd_Smed_v6_786_0_1, dd_Smed_v6_786_0_1, [Score=208, Expect=1e-66]} {RNA1509_4740} {RNA1310_29116} {RNA815_12893}

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