Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_05885 | 516 | 10.76 | Mlig455_011335 | Neo: - Age: logFC(26M/2M)=-0.395 |
MAP3K19 | Mlig455_011335 {REF} {Length: 6983} {Pfam: Protein kinase domain [PF00069.27, score=287.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=180.9]; Ankyrin repeats (many copies) [PF13637.8, score=56.3]; Ankyrin repeats (3 copies) [PF12796.9, score=55.0]; Apolipoprotein L [PF05461.13, score=39.2]; Ankyrin repeat [PF13606.8, score=37.3]; Ankyrin repeats (many copies) [PF13857.8, score=32.7]; Ankyrin repeat [PF00023.32, score=31.2]; Phosphotransferase enzyme family [PF01636.25, score=21.2]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=118, Expect=4e-27]; ENSG00000163482, STK36, serine/threonine kinase 36, [Score=114, Expect=6e-25]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=115, Expect=4e-26]; ENSMUSG00000033276, Stk36, serine/threonine kinase 36, [Score=113, Expect=1e-24]; ENSMUSG00000020389, Cdkl3, cyclin-dependent kinase-like 3, [Score=112, Expect=7e-25]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=104, Expect=4e-22]} {Celegans: WBGene00019801, aak-1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, [Score=97.1, Expect=2e-20]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=108, Expect=1e-23]} {RNA1509_1087, RNA1509_13350, RNA1509_21157, RNA1509_56155, RNA1509_58761} {RNA1310_1574, RNA1509_13350, RNA1509_21157, RNA1509_56155, RNA1509_58761} {RNA1509_13350, RNA1509_21157, RNA1509_56155, RNA1509_58761, RNA815_525.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 1.521 | 3.768 | 0.16516 | 0.78916 | |
RegionR2 | 0.343 | 3.768 | 0.54341 | 0.91027 | |
RegionR3 | 0.54 | 3.768 | 0.23498 | 0.77670 | |
RegionR4 | 0.791 | 3.768 | 0.13878 | 0.37991 | |
RegionR5 | -0.127 | 3.768 | 0.78855 | 1.00000 | |
RegionR6 | 0.106 | 3.768 | 0.82395 | 1.00000 | |
RegionR7 | -0.952 | 3.768 | 0.18846 | 0.79140 | |
RegionR8 | -2.222 | 3.768 | 0.05534 | 0.45964 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -2.686 | 3.768 | 0.11112 | 0.83505 | |
RegenerationR2 | 0.086 | 3.768 | 0.85116 | 1.00000 | |
RegenerationR3 | -0.553 | 3.768 | 0.27401 | 0.70840 | |
RegenerationR4 | -1.067 | 3.768 | 0.04290 | 0.33331 | |
RegenerationR5 | -0.739 | 3.768 | 0.14840 | 0.56539 | |
RegenerationR6 | -0.51 | 3.768 | 0.32847 | 0.67498 | |
RegenerationBL | 0.414 | 3.768 | 0.58188 | 0.93375 | |
RegenerationTP | 1.054 | 3.768 | 0.23564 | 0.68121 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_05885 | 516 | 10.76 | Mlig455_011335 | Neo: - Age: logFC(26M/2M)=-0.395 |
MAP3K19 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_011335 {REF} {Length: 6983} {Pfam: Protein kinase domain [PF00069.27, score=287.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=180.9]; Ankyrin repeats (many copies) [PF13637.8, score=56.3]; Ankyrin repeats (3 copies) [PF12796.9, score=55.0]; Apolipoprotein L [PF05461.13, score=39.2]; Ankyrin repeat [PF13606.8, score=37.3]; Ankyrin repeats (many copies) [PF13857.8, score=32.7]; Ankyrin repeat [PF00023.32, score=31.2]; Phosphotransferase enzyme family [PF01636.25, score=21.2]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=118, Expect=4e-27]; ENSG00000163482, STK36, serine/threonine kinase 36, [Score=114, Expect=6e-25]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=115, Expect=4e-26]; ENSMUSG00000033276, Stk36, serine/threonine kinase 36, [Score=113, Expect=1e-24]; ENSMUSG00000020389, Cdkl3, cyclin-dependent kinase-like 3, [Score=112, Expect=7e-25]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=104, Expect=4e-22]} {Celegans: WBGene00019801, aak-1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, [Score=97.1, Expect=2e-20]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=108, Expect=1e-23]} {RNA1509_1087, RNA1509_13350, RNA1509_21157, RNA1509_56155, RNA1509_58761} {RNA1310_1574, RNA1509_13350, RNA1509_21157, RNA1509_56155, RNA1509_58761} {RNA1509_13350, RNA1509_21157, RNA1509_56155, RNA1509_58761, RNA815_525.1} |
2. | MligTC455_40423 | 752 | 15.66 | Mlig455_029299, Mlig455_058869 | Neo: - Age: Down-Up-Down |
CALM1 | 1.876 | - | - | 0.954 | - | - | 0.922 | Mlig455_029299 {REF} {Length: 1144} {Pfam: EF-hand domain pair [PF13833.8, score=47.6]; EF-hand domain pair [PF13499.8, score=39.7]; EF hand [PF00036.34, score=31.4]; EF-hand domain [PF13405.8, score=29.4]; EF-hand domain [PF14658.8, score=24.4]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=100, Expect=1e-26]; ENSG00000143933, CALM2, calmodulin 2, [Score=100, Expect=1e-26]; ENSG00000160014, CALM3, calmodulin 3, [Score=100, Expect=1e-26]; ENSG00000178363, CALML3, calmodulin like 3, [Score=95.1, Expect=1e-24]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=100, Expect=8e-27]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=100, Expect=8e-27]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=100, Expect=8e-27]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=98.2, Expect=4e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=98.2, Expect=4e-26]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=98.2, Expect=3e-26]} {RNA1509_16604} {RNA1310_33121} {RNA815_17390} Mlig455_058869 {REF} {Length: 1325} {Pfam: EF-hand domain pair [PF13833.8, score=47.6]; EF-hand domain pair [PF13499.8, score=39.7]; EF hand [PF00036.34, score=31.4]; EF-hand domain [PF13405.8, score=29.4]; EF-hand domain [PF14658.8, score=24.4]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=100, Expect=1e-26]; ENSG00000143933, CALM2, calmodulin 2, [Score=100, Expect=1e-26]; ENSG00000160014, CALM3, calmodulin 3, [Score=100, Expect=1e-26]; ENSG00000178363, CALML3, calmodulin like 3, [Score=95.1, Expect=1e-24]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=100, Expect=8e-27]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=100, Expect=8e-27]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=100, Expect=8e-27]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=98.2, Expect=4e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=98.2, Expect=4e-26]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=98.2, Expect=3e-26]} {RNA1509_16604} {RNA1310_33121, RNA1509_16604} {RNA1509_16604, RNA815_17390} |
3. | MligTC455_39525 | 26 | 0.54 | Mlig455_046789 | Neo: - Age: - |
1.732 | - | - | - | 0.781 | 0.951 | - | Mlig455_046789 {REF} {Length: 670} {RNA1509_44223} {RNA1310_99471} {RNA815_64986} | |
4. | MligTC455_25733 | 284 | 5.92 | Mlig455_046183 | Neo: - Age: Down-Up-Down |
UBE2H | 0.969 | - | - | - | 0.969 | - | - | Mlig455_046183 {REF} {Length: 3803} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=123.4]} {Human: ENSG00000186591, UBE2H, ubiquitin conjugating enzyme E2 H, [RH, Score=300, Expect=2e-104]} {Mouse: ENSMUSG00000039159, Ube2h, ubiquitin-conjugating enzyme E2H, [RH, Score=300, Expect=1e-104]} {Dmel: FBgn0029996, UbcE2H, Ubiquitin conjugating enzyme E2H, [RH, Score=272, Expect=1e-93]} {Celegans: WBGene00006705, ubc-8, UBiquitin Conjugating enzyme, [RH, Score=249, Expect=4e-84]} {Smed: dd_Smed_v6_4514_0_1, dd_Smed_v6_4514_0_1, [RH, Score=267, Expect=9e-92]} {RNA1509_28957, RNA1509_40439} {RNA1310_30434.2, RNA1509_28957, RNA1509_40439} {RNA1509_28957, RNA1509_40439, RNA815_15106.1} |
5. | MligTC455_23532 | 341 | 7.1 | Mlig455_008838 | Neo: - Age: - |
PYCR2 | 0.958 | - | - | - | 0.958 | - | - | Mlig455_008838 {REF} {Length: 2169} {TRANSSPLICED} {Pfam: Pyrroline-5-carboxylate reductase dimerisation [PF14748.8, score=122.2]; NADP oxidoreductase coenzyme F420-dependent [PF03807.19, score=76.5]; Ornithine cyclodeaminase/mu-crystallin family [PF02423.17, score=25.3]; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus [PF01210.25, score=24.3]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=20.0]} {Human: ENSG00000143811, PYCR2, pyrroline-5-carboxylate reductase 2, [RH, Score=236, Expect=2e-76]; ENSG00000183010, PYCR1, pyrroline-5-carboxylate reductase 1, [RH, Score=233, Expect=2e-75]} {Mouse: ENSMUSG00000025140, Pycr1, pyrroline-5-carboxylate reductase 1, [RH, Score=233, Expect=1e-75]; ENSMUSG00000026520, Pycr2, pyrroline-5-carboxylate reductase family, member 2, [RH, Score=229, Expect=4e-74]} {Dmel: FBgn0038516, P5cr-2, Pyrroline-5-carboxylate reductase-like 2, [RH, Score=213, Expect=2e-68]} {Celegans: WBGene00010924, M153.1, [RH, Score=214, Expect=4e-69]} {Smed: dd_Smed_v6_3217_0_2, dd_Smed_v6_3217_0_2, [Score=162, Expect=1e-48]} {RNA1509_53797} {RNA1310_24990, RNA1509_53797} {RNA1509_53797, RNA815_21427} |
6. | MligTC455_42132 | 837 | 17.43 | Mlig455_012837 | Neo: - Age: logFC(26M/2M)=-0.387 |
EFCAB6 | 0.958 | - | - | - | - | - | 0.958 | Mlig455_012837 {REF} {Length: 5469} {Pfam: EF-hand domain pair [PF13499.8, score=199.1]; EF-hand domain [PF08976.13, score=153.8]; EF-hand domain [PF13405.8, score=129.1]; EF hand [PF00036.34, score=112.1]; EF-hand domain pair [PF13833.8, score=77.4]; EF hand [PF13202.8, score=44.2]; Family of unknown function (DUF5580) [PF17743.3, score=35.6]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [RH, Score=389, Expect=1e-111]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=373, Expect=4e-106]} {Smed: dd_Smed_v6_7065_0_1, dd_Smed_v6_7065_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_39025} {RNA1310_902.1} {RNA815_763} |
7. | MligTC455_49022 | 378 | 7.87 | Mlig455_008757 | Neo: - Age: - |
0.956 | - | - | 0.956 | - | - | - | Mlig455_008757 {REF} {Length: 1456} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=24.1]; Lipopolysaccharide assembly protein A domain [PF06305.13, score=19.0]} {Smed: dd_Smed_v6_2114_0_1, dd_Smed_v6_2114_0_1, [RH, Score=130, Expect=5e-36]} {RNA1509_42918} {RNA1310_17906} {RNA815_7308.1} | |
8. | MligTC455_28295 | 471 | 9.82 | Mlig455_034661 | Neo: - Age: - |
0.954 | - | - | 0.954 | - | - | - | Mlig455_034661 {REF} {Length: 526} {RNA1310_61099} {RNA815_29618} | |
9. | MligTC455_19360 | 1380 | 28.75 | Mlig455_065641 | Neo: - Age: logFC(26M/2M)=-0.869 |
0.953 | - | - | - | - | - | 0.953 | Mlig455_065641 {REF} {Length: 843} {RNA1509_52437} {RNA1310_43315.2} {RNA815_22018.1} | |
10. | MligTC455_41793 | 128 | 2.66 | Mlig455_056389 | Neo: - Age: logFC(26M/2M)=-0.406 |
CCDC96 | 0.951 | - | - | 0.951 | - | - | - | Mlig455_056389 {REF} {Length: 2189} {Pfam: Domain of unknown function (DUF4201) [PF13870.8, score=154.7]} {Human: ENSG00000173013, CCDC96, coiled-coil domain containing 96, [RH, Score=195, Expect=5e-54]} {Mouse: ENSMUSG00000050677, Ccdc96, coiled-coil domain containing 96, [RH, Score=195, Expect=4e-54]} {Smed: dd_Smed_v6_9313_0_1, dd_Smed_v6_9313_0_1, [RH, Score=201, Expect=5e-59]} {RNA1509_26742, RNA1509_58369} {RNA1310_8172.1, RNA1509_58369} {RNA1509_58369, RNA815_3762} |
11. | MligTC455_44157 | 2728 | 56.84 | Mlig455_015483 | Neo: - Age: logFC(26M/2M)=-0.621 Region-enriched R4: 1.377/0.00397 |
SPAG8 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_015483 {REF} {Length: 1025} {Human: ENSG00000137098, SPAG8, sperm associated antigen 8, [RH, Score=83.2, Expect=3e-18]} {Mouse: ENSMUSG00000066196, Spag8, sperm associated antigen 8, [RH, Score=90.9, Expect=4e-21]} {Smed: dd_Smed_v6_6123_0_1, dd_Smed_v6_6123_0_1, [RH, Score=131, Expect=1e-38]} {RNA1509_3548} {RNA1310_4106} {RNA815_16577} |
12. | MligTC455_48409 | 252 | 5.25 | Mlig455_000937 | Neo: - Age: logFC(26M/2M)=-1.004 |
0.951 | - | - | - | 0.951 | - | - | Mlig455_000937 {REF} {Length: 3906} {Pfam: Mab-21 protein [PF03281.16, score=40.8]} {RNA1509_23744, RNA1509_44882} {RNA1310_5050.1, RNA1509_23744, RNA1509_44882} {RNA1509_23744, RNA1509_44882, RNA815_9143} | |
13. | MligTC455_50914 | 714 | 14.87 | Mlig455_005873 | Neo: - Age: - Region-enriched R2: 2.125/0.01399 |
DNHD1 | 0.95 | - | - | - | - | - | 0.950 | Mlig455_005873 {REF} {Length: 14506} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=207.8]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=114.3]; P-loop containing dynein motor region D4 [PF12780.9, score=60.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=54.5]; P-loop containing dynein motor region [PF12775.9, score=46.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=42.8]; Dynein heavy chain AAA lid domain [PF17852.3, score=38.9]; AAA domain [PF13401.8, score=22.7]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=20.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=19.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=159, Expect=1e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=177, Expect=3e-43]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=4e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=82.0, Expect=1e-14]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [Score=331, Expect=5e-90]} {RNA1509_32900} {RNA1310_31} {RNA815_1203} |