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Results for MligTC455_08811

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_08811 162 3.38 Mlig455_054365

Neo: -

Age: Down-Down-Down

 Mlig455_054365 {REF} {Length: 881} {RNA1509_52541} {RNA1310_78287} {RNA815_41027}

Cumulative graph for MligTC455_08811

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.088 2.28 0.29458 0.94570
RegionR2 2.421 2.28 0.00601 0.07248
RegionR3 -0.029 2.28 0.98059 1.00000
RegionR4 -1.536 2.28 0.07309 0.24939
RegionR5 1.322 2.28 0.02138 0.10167
RegionR6 0.017 2.28 0.97133 1.00000
RegionR7 -0.879 2.28 0.51905 1.00000
RegionR8 0.772 2.28 0.56294 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 5.358 2.28 0.00982 0.44095
RegenerationR2 -0.143 2.28 0.84962 1.00000
RegenerationR3 0.702 2.28 0.42827 0.82003
RegenerationR4 0.841 2.28 0.30820 0.74899
RegenerationR5 0.378 2.28 0.54012 0.88028
RegenerationR6 0.645 2.28 0.51586 0.81717
RegenerationBL -1.156 2.28 0.50991 0.87358
RegenerationTP 2.314 2.28 0.03487 0.31204


Genes with expression patterns similar to MligTC455_08811

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_08811 162 3.38 Mlig455_054365

Neo: -

Age: Down-Down-Down

 5 1.000 1.000 1.000 - 1.000 1.000 Mlig455_054365 {REF} {Length: 881} {RNA1509_52541} {RNA1310_78287} {RNA815_41027}
2. MligTC455_08810 173 3.6 Mlig455_054289

Neo: -

Age: Up-Down-Up

 LIMK1 4.98 0.999 1.000 1.000 - 0.982 0.999 Mlig455_054289 {REF} {Length: 2786} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=138.3]; Protein kinase domain [PF00069.27, score=130.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.1]} {Human: ENSG00000106683, LIMK1, LIM domain kinase 1, [Score=175, Expect=9e-49]} {Mouse: ENSMUSG00000029674, Limk1, LIM-domain containing, protein kinase, [Score=172, Expect=4e-48]} {Dmel: FBgn0283712, LIMK1, LIM domain kinase 1, [Score=163, Expect=3e-44]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [Score=105, Expect=1e-24]} {Smed: dd_Smed_v6_4373_0_1, dd_Smed_v6_4373_0_1, [Score=117, Expect=2e-29]} {RNA1509_32349} {RNA1310_20379.1, RNA1509_32349} {RNA1509_32349, RNA815_32665}
3. MligTC455_33756 416 8.66 Mlig455_012072

Neo: Int S/G2/M

Age: Down-Up-Down

Region-enriched R5: 1.414/0.00045

 STOML2 2.566 0.863 - 0.970 - - 0.733 Mlig455_012072 {REF} {Length: 1957} {TRANSSPLICED} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=97.6]; C-terminal region of band_7 [PF16200.7, score=82.5]} {Human: ENSG00000165283, STOML2, stomatin like 2, [RH, Score=405, Expect=1e-139]} {Mouse: ENSMUSG00000028455, Stoml2, stomatin (Epb7.2)-like 2, [RH, Score=400, Expect=2e-137]} {Dmel: FBgn0034936, CG2970, [RH, Score=379, Expect=3e-129]} {Celegans: WBGene00006061, stl-1, STomatin-Like, [RH, Score=375, Expect=2e-128]} {Smed: dd_Smed_v6_2211_0_1, dd_Smed_v6_2211_0_1, [RH, Score=379, Expect=2e-129]} {RNA1509_7007} {RNA1310_10106} {RNA815_7823}
4. MligTC455_52782 103 2.15 Mlig455_020826

Neo: -

Age: Down-Up-Down

Region-enriched R5: 3.206/0.01220

 RCOR3 1.748 0.797 - - - 0.951 - Mlig455_020826 {REF} {Length: 3804} {Pfam: Myb-like DNA-binding domain [PF00249.33, score=64.4]; Myb DNA-binding like [PF15963.7, score=26.6]; Myb-like DNA-binding domain [PF13921.8, score=26.1]; ELM2 domain [PF01448.26, score=22.8]} {Human: ENSG00000117625, RCOR3, REST corepressor 3, [RH, Score=247, Expect=8e-77]} {Mouse: ENSMUSG00000037395, Rcor3, REST corepressor 3, [RH, Score=249, Expect=1e-77]; ENSMUSG00000111452, Rcor3, REST corepressor 3, [RH, Score=249, Expect=1e-77]} {Dmel: FBgn0261573, CoRest, [RH, Score=172, Expect=1e-46]} {Celegans: WBGene00010012, saeg-1, Suppressor of activated egl-4 protein 1, [Score=52.0, Expect=6e-07]} {RNA1509_18242} {RNA1310_10015.1} {RNA815_28312.1}
5. MligTC455_33060 100 2.08 Mlig455_045901

Neo: Germline

Age: Up-Down-Up

Region-enriched R5: 3.781/0.00002

 1.72 - - 0.769 - - 0.951 Mlig455_045901 {REF} {Length: 2137} {Pfam: Immunoglobulin domain [PF13927.8, score=49.5]; Immunoglobulin domain [PF13895.8, score=47.1]; Immunoglobulin I-set domain [PF07679.18, score=41.6]; Immunoglobulin V-set domain [PF07686.19, score=29.8]; Immunoglobulin domain [PF00047.27, score=27.2]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=53.1, Expect=7e-07]} {Smed: dd_Smed_v6_2673_0_1, dd_Smed_v6_2673_0_1, [Score=50.4, Expect=3e-06]} {RNA1509_12903} {RNA1310_11861, RNA1509_12903} {RNA1509_12903, RNA815_4505}
6. MligTC455_26002 237 4.93 Mlig455_003520

Neo: -

Age: -

 RAB8B 1.709 - - 0.726 - - 0.983 Mlig455_003520 {REF} {Length: 1926} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=21.6]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=54.7, Expect=2e-10]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=54.3, Expect=3e-10]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=56.2, Expect=4e-11]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=55.8, Expect=6e-11]} {Dmel: FBgn0262518, Rab8, [Score=48.1, Expect=3e-08]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=50.8, Expect=3e-09]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=50.1, Expect=4e-09]} {RNA1509_12702} {RNA1310_26159.1} {RNA815_11534.2}
7. MligTC455_51180 590 12.29 Mlig455_012498, Mlig455_012587

Neo: -

Age: -

 1.69 0.735 - - - 0.955 -

Mlig455_012498 {REF} {Length: 3214} {TRANSSPLICED} {Pfam: RUN domain [PF02759.21, score=55.2]} {Smed: dd_Smed_v6_12193_0_1, dd_Smed_v6_12193_0_1, [RH, Score=58.2, Expect=1e-08]} {RNA1509_18736} {RNA1310_14745, RNA1509_18736} {RNA1509_18736, RNA815_5188}

Mlig455_012587 {REF} {Length: 3216} {TRANSSPLICED} {Pfam: RUN domain [PF02759.21, score=52.3]} {Smed: dd_Smed_v6_6417_0_1, dd_Smed_v6_6417_0_1, [RH, Score=52.8, Expect=4e-07]} {RNA1509_18736} {RNA1310_14745} {RNA815_5188}
8. MligTC455_39949 78 1.63 Mlig455_062594

Neo: -

Age: Down-Up-Down

 0.987 - - 0.987 - - - Mlig455_062594 {REF} {Length: 1930} {NoTransDecoderORF} {RNA1310_17694.1} {RNA815_30420}
9. MligTC455_34253 1073 22.35 Mlig455_035968

Neo: -

Age: -

Region-enriched R5: 1.204/0.04277

 PGK1 0.98 - - - - 0.980 - Mlig455_035968 {REF} {Length: 2381} {Pfam: Phosphoglycerate kinase [PF00162.21, score=488.1]} {Human: ENSG00000102144, PGK1, phosphoglycerate kinase 1, [RH, Score=588, Expect=0.0]; ENSG00000170950, PGK2, phosphoglycerate kinase 2, [RH, Score=585, Expect=0.0]} {Mouse: ENSMUSG00000062070, Pgk1, phosphoglycerate kinase 1, [RH, Score=587, Expect=0.0]; ENSMUSG00000031233, Pgk2, phosphoglycerate kinase 2, [RH, Score=572, Expect=0.0]} {Dmel: FBgn0250906, Pgk, Phosphoglycerate kinase, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00020185, pgk-1, Probable phosphoglycerate kinase, [RH, Score=605, Expect=0.0]} {Smed: dd_Smed_v6_972_0_1, dd_Smed_v6_972_0_1, [RH, Score=602, Expect=0.0]} {RNA1509_1929, RNA1509_24971} {RNA1310_10765.1, RNA1509_1929, RNA1509_24971} {RNA1509_1929, RNA1509_24971, RNA815_5032.1}
10. MligTC455_52939 40 0.84 Mlig455_010311

Neo: -

Age: -

 0.979 - - - - 0.979 - Mlig455_010311 {REF} {Length: 1147} {Pfam: Domain of unknown function (DUF4271) [PF14093.8, score=18.9]} {RNA1310_110667}
11. MligTC455_41372 927 19.32 Mlig455_040212

Neo: Neoblast

Age: -

 NUDT21 0.977 - - - - 0.977 - Mlig455_040212 {REF} {Length: 1662} {TRANSSPLICED} {Pfam: Nucleotide hydrolase [PF13869.8, score=257.3]} {Human: ENSG00000167005, NUDT21, nudix hydrolase 21, [RH, Score=293, Expect=1e-101]} {Mouse: ENSMUSG00000031754, Nudt21, nudix (nucleoside diphosphate linked moiety X)-type motif 21, [RH, Score=293, Expect=1e-101]} {Dmel: FBgn0035987, CG3689, [RH, Score=286, Expect=7e-99]} {Celegans: WBGene00009668, cfim-1, Cleavage Factor IM (CFIm) homolog, [RH, Score=275, Expect=7e-95]} {Smed: dd_Smed_v6_4067_0_2, dd_Smed_v6_4067_0_2, [RH, Score=284, Expect=2e-98]} {RNA1509_30613, RNA1509_32408} {RNA1310_18617, RNA1509_30613, RNA1509_32408} {RNA1509_30613, RNA1509_32408, RNA815_19534.1}
12. MligTC455_21238 129 2.69 Mlig455_005974

Neo: -

Age: -

Region-enriched R5: 1.628/0.01619

 0.976 - - - - 0.976 - Mlig455_005974 {REF} {Length: 382} {NoTransDecoderORF} {RNA1509_57525} {RNA1310_118595} {RNA815_10590.1}
13. MligTC455_13921 220 4.58 Mlig455_045722

Neo: -

Age: -

Region-enriched R6: 3.243/0.00161
Region-enriched R5: 3.053/0.00017

 0.974 - - - - - 0.974 Mlig455_045722 {REF} {Length: 1184} {NoTransDecoderORF} {RNA1509_45086} {RNA1310_33791, RNA1509_45086} {RNA1509_45086, RNA815_26629.1}
14. MligTC455_12116 106 2.2 Mlig455_004661, Mlig455_004728

Neo: -

Age: Up-Up-Down

 0.973 - - - - 0.973 -

Mlig455_004661 {REF} {Length: 3441} {RNA1509_48407} {RNA1310_2938.1} {RNA815_14343.2}

Mlig455_004728 {REF} {Length: 2670} {RNA1509_48407} {RNA1310_45267.1, RNA1509_48407} {RNA1509_48407, RNA815_58661}
15. MligTC455_34786 265 5.52 Mlig455_048038

Neo: -

Age: -

 0.97 - - - - - 0.970 Mlig455_048038 {REF} {Length: 2713} {TRANSSPLICED} {RNA1509_16012, RNA1509_45749} {RNA1310_42575.1, RNA1509_16012, RNA1509_45749} {RNA1509_16012, RNA1509_45749, RNA815_38389}
16. MligTC455_06814 49 1.02 Mlig455_046899

Neo: -

Age: -

 0.969 - - - - 0.969 - Mlig455_046899 {REF} {Length: 337}
17. MligTC455_13630 103 2.15 Mlig455_015975, Mlig455_015995

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.335

 0.969 - - 0.969 - - -

Mlig455_015975 {REF} {Length: 3240} {tRNA: Val(CAC),pseudo, score=22.4} {RNA1509_22695} {RNA1310_13430.1, RNA1509_22695} {RNA1509_22695, RNA815_19328.1}

Mlig455_015995 {REF} {Length: 3774} {tRNA: Val(CAC),pseudo, score=22.4} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=18.9]} {RNA1509_22695} {RNA1310_13430.1} {RNA815_4308.1}
18. MligTC455_07684 42 0.88 Mlig455_022129

Neo: -

Age: -

 0.967 - - - - 0.967 - Mlig455_022129 {REF} {Length: 443} {NoTransDecoderORF} {RNA1310_69626}
19. MligTC455_29653 200 4.17 Mlig455_009145

Neo: -

Age: logFC(26M/2M)=0.607

 SETMAR 0.967 - - - - 0.967 - Mlig455_009145 {REF} {Length: 2358} {TRANSSPLICED} {Pfam: DDE superfamily endonuclease [PF13358.8, score=32.4]; Winged helix-turn helix [PF13551.8, score=31.6]; Homeodomain-like domain [PF13384.8, score=29.0]; Bacterial regulatory proteins, lacI family [PF00356.23, score=28.5]; Helix-turn-helix domain of resolvase [PF02796.17, score=24.3]; Helix-turn-helix domain [PF13518.8, score=23.4]; Bacterial regulatory proteins, tetR family [PF00440.25, score=23.1]; Helix-turn-helix [PF01381.24, score=21.9]; Winged helix-turn-helix DNA-binding [PF13412.8, score=21.4]; MarR family [PF12802.9, score=21.3]; Sugar-specific transcriptional regulator TrmB [PF01978.21, score=21.0]; HTH DNA binding domain [PF04967.14, score=21.0]; AsnC-type helix-turn-helix domain [PF13404.8, score=20.3]; Transposase [PF01498.20, score=19.3]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=62.4, Expect=3e-10]} {Smed: dd_Smed_v6_16239_0_2, dd_Smed_v6_16239_0_2, [Score=69.3, Expect=4e-14]} {RNA1509_272} {RNA1310_26410} {RNA815_12134}
20. MligTC455_39919 472 9.84 Mlig455_009244, Mlig455_009648, Mlig455_037054

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.798

 0.965 - - - - 0.965 -

Mlig455_009244 {REF} {Length: 812} {NoTransDecoderORF} {tRNA: Val(CAC),pseudo, score=21.7} {RNA1509_9666} {RNA1310_72404} {RNA815_3434}

Mlig455_009648 {REF} {Length: 773} {NoTransDecoderORF} {tRNA: Val(CAC),pseudo, score=21.7} {RNA1509_9666} {RNA1310_72404} {RNA815_3434}

Mlig455_037054 {REF} {Length: 394} {NoTransDecoderORF} {RNA1509_466} {RNA1310_10184.1} {RNA815_3434}
21. MligTC455_40136 198 4.13 Mlig455_015773

Neo: -

Age: logFC(26M/2M)=0.466

 IDNK 0.964 - - 0.964 - - - Mlig455_015773 {REF} {Length: 3709} {TRANSSPLICED} {Pfam: Shikimate kinase [PF01202.24, score=34.9]; AAA domain [PF13671.8, score=29.0]; AAA domain [PF13238.8, score=26.3]; AAA domain [PF13521.8, score=21.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.5]; AAA ATPase domain [PF13191.8, score=19.6]} {Human: ENSG00000148057, IDNK, IDNK, gluconokinase, [RH, Score=123, Expect=4e-35]} {Mouse: ENSMUSG00000050002, Idnk, idnK gluconokinase homolog (E. coli), [RH, Score=128, Expect=2e-37]} {Celegans: WBGene00017818, F26D11.1, Gluconokinase, [RH, Score=128, Expect=8e-38]} {Smed: dd_Smed_v6_14936_0_1, dd_Smed_v6_14936_0_1, [RH, Score=110, Expect=6e-31]} {RNA1509_48460} {RNA1310_24189, RNA1509_48460} {RNA1509_48460, RNA815_32058}
22. MligTC455_24695 174 3.63 Mlig455_048635

Neo: -

Age: -

 FAU 0.963 - - - - 0.963 - Mlig455_048635 {REF} {Length: 350} {TRANSSPLICED} {Pfam: Ribosomal protein S30 [PF04758.16, score=95.8]} {Human: ENSG00000149806, FAU, FAU, ubiquitin like and ribosomal protein S30 fusion, [Score=83.6, Expect=2e-21]} {Mouse: ENSMUSG00000038274, Fau, Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), [Score=82.8, Expect=4e-21]} {Dmel: FBgn0038834, RpS30, Ribosomal protein S30, [RH, Score=87.0, Expect=5e-23]} {Celegans: WBGene00004499, rps-30, 40S ribosomal protein S30, [RH, Score=72.4, Expect=2e-17]} {Smed: dd_Smed_v6_126_0_1, dd_Smed_v6_126_0_1, [Score=92.0, Expect=6e-25]} {RNA1509_7814} {RNA1310_56942} {RNA815_29383}
23. MligTC455_54021 1302 27.12 Mlig455_011593, Mlig455_050000

Neo: -

Age: -

 PUM2 0.963 - - - - 0.963 -

Mlig455_011593 {REF} {Length: 5544} {TRANSSPLICED} {Pfam: Pumilio-family RNA binding repeat [PF00806.21, score=296.7]; CPL (NUC119) domain [PF08144.13, score=19.8]; Protein of unknown function (DUF445) [PF04286.14, score=19.7]} {Human: ENSG00000055917, PUM2, pumilio RNA binding family member 2, [RH, Score=531, Expect=5e-174]; ENSG00000134644, PUM1, pumilio RNA binding family member 1, [RH, Score=530, Expect=2e-173]} {Mouse: ENSMUSG00000020594, Pum2, pumilio RNA-binding family member 2, [RH, Score=531, Expect=1e-173]; ENSMUSG00000106966, Pum1, pumilio RNA-binding family member 1, [RH, Score=526, Expect=3e-172]; ENSMUSG00000028580, Pum1, pumilio RNA-binding family member 1, [RH, Score=526, Expect=3e-172]} {Dmel: FBgn0003165, pum, pumilio, [RH, Score=511, Expect=5e-161]} {Celegans: WBGene00004245, puf-9, PUF (Pumilio/FBF) domain-containing, [RH, Score=388, Expect=1e-122]} {Smed: dd_Smed_v6_1677_0_1, dd_Smed_v6_1677_0_1, [RH, Score=504, Expect=4e-164]} {RNA1509_24495, RNA1509_3668, RNA1509_59306} {RNA1310_1864.1, RNA1509_24495, RNA1509_59306} {RNA1509_24495, RNA1509_59306, RNA815_1730.2}

Mlig455_050000 {REF} {Length: 5309} {TRANSSPLICED} {Pfam: Pumilio-family RNA binding repeat [PF00806.21, score=296.4]; Protein of unknown function (DUF445) [PF04286.14, score=19.8]; CPL (NUC119) domain [PF08144.13, score=19.7]} {Human: ENSG00000055917, PUM2, pumilio RNA binding family member 2, [RH, Score=531, Expect=4e-173]; ENSG00000134644, PUM1, pumilio RNA binding family member 1, [RH, Score=530, Expect=3e-171]} {Mouse: ENSMUSG00000020594, Pum2, pumilio RNA-binding family member 2, [RH, Score=531, Expect=2e-173]; ENSMUSG00000028580, Pum1, pumilio RNA-binding family member 1, [RH, Score=526, Expect=5e-172]; ENSMUSG00000106966, Pum1, pumilio RNA-binding family member 1, [RH, Score=526, Expect=5e-172]} {Dmel: FBgn0003165, pum, pumilio, [RH, Score=511, Expect=5e-161]} {Celegans: WBGene00004245, puf-9, PUF (Pumilio/FBF) domain-containing, [RH, Score=388, Expect=2e-122]} {Smed: dd_Smed_v6_1677_0_1, dd_Smed_v6_1677_0_1, [RH, Score=504, Expect=3e-164]} {RNA1509_21797, RNA1509_28076, RNA1509_33435, RNA1509_3668, RNA1509_57796} {RNA1310_1864.1, RNA1509_21797, RNA1509_28076, RNA1509_33435, RNA1509_3668, RNA1509_57796} {RNA1509_21797, RNA1509_28076, RNA1509_33435, RNA1509_3668, RNA1509_57796, RNA815_1730.1}
24. MligTC455_19107 490 10.21 Mlig455_002175, Mlig455_002276

Neo: Germline

Age: Up-Down-Up

Region-enriched R5: 1.406/0.00276

 PSMC3IP 0.962 - - 0.962 - - -

Mlig455_002175 {REF} {Length: 1599} {TRANSSPLICED} {Pfam: TBPIP/Hop2 winged helix domain [PF07106.15, score=92.4]; Leucine zipper with capping helix domain [PF18517.3, score=39.8]} {Human: ENSG00000131470, PSMC3IP, PSMC3 interacting protein, [RH, Score=128, Expect=2e-36]} {Mouse: ENSMUSG00000019303, Psmc3ip, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein, [RH, Score=147, Expect=7e-44]} {Smed: dd_Smed_v6_15163_0_1, dd_Smed_v6_15163_0_1, [RH, Score=134, Expect=4e-39]} {RNA1509_36312} {RNA1310_45817.2} {RNA815_29085.1}

Mlig455_002276 {REF} {Length: 1717} {TRANSSPLICED} {Pfam: TBPIP/Hop2 winged helix domain [PF07106.15, score=92.3]; Leucine zipper with capping helix domain [PF18517.3, score=39.8]; Filament-like plant protein, long coiled-coil [PF05911.13, score=21.4]; Penicillinase repressor [PF03965.18, score=19.7]} {Human: ENSG00000131470, PSMC3IP, PSMC3 interacting protein, [RH, Score=130, Expect=3e-37]} {Mouse: ENSMUSG00000019303, Psmc3ip, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein, [RH, Score=146, Expect=2e-43]} {Smed: dd_Smed_v6_15163_0_1, dd_Smed_v6_15163_0_1, [RH, Score=139, Expect=3e-41]} {RNA1509_18951} {RNA1310_38683} {RNA815_16821}
25. Mlig999020.1 0.961 - - - - 0.961 -
26. MligTC455_40029 127 2.64 Mlig455_000944

Neo: -

Age: -

 MAP3K9 0.96 - - 0.960 - - - Mlig455_000944 {REF} {Length: 5547} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=143.4]; Protein kinase domain [PF00069.27, score=122.4]; Variant SH3 domain [PF14604.8, score=20.5]; SH3 domain [PF00018.30, score=19.2]} {Human: ENSG00000006432, MAP3K9, mitogen-activated protein kinase kinase kinase 9, [RH, Score=282, Expect=2e-78]} {Mouse: ENSMUSG00000042724, Map3k9, mitogen-activated protein kinase kinase kinase 9, [RH, Score=284, Expect=2e-79]} {Dmel: FBgn0030018, slpr, slipper, [RH, Score=242, Expect=3e-65]} {Celegans: WBGene00003374, mlk-1, Mitogen-activated protein kinase kinase kinase mlk-1, [RH, Score=140, Expect=2e-33]} {Smed: dd_Smed_v6_8838_0_1, dd_Smed_v6_8838_0_1, [Score=136, Expect=2e-32]} {RNA1509_21185} {RNA1310_3788.2} {RNA815_27222}
27. MligTC455_40741 306 6.38 Mlig455_062243

Neo: -

Age: -

 0.96 - - - - 0.960 - Mlig455_062243 {REF} {Length: 1935} {RNA1509_17197, RNA1509_50186} {RNA1310_23515, RNA1509_50186} {RNA1509_50186, RNA815_9818}
28. MligTC455_19932 461 9.61 Mlig455_019596, Mlig455_059100

Neo: -

Age: -

 0.959 - - - - - 0.959

Mlig455_019596 {REF} {Length: 3118} {TRANSSPLICED} {RNA1509_20980} {RNA1310_30814.1} {RNA815_36360}

Mlig455_059100 {REF} {Length: 3656} {TRANSSPLICED} {RNA1509_20980, RNA1509_28513} {RNA1310_30814.1, RNA1509_28513} {RNA1509_28513, RNA815_36360}
29. MligTC455_28851 635 13.22 Mlig455_015966, Mlig455_015985, Mlig455_016082, Mlig455_041037, Mlig455_051413, Mlig455_059417

Neo: -

Age: -

 0.959 - - - - 0.959 -

Mlig455_015966 {REF} {Length: 4813} {RNA1509_34937} {RNA1310_2313.1} {RNA815_7759.1}

Mlig455_015985 {REF} {Length: 5033} {RNA1509_34937, RNA1509_37327} {RNA1310_2313.1, RNA1509_37327} {RNA1509_37327, RNA815_7759.1}

Mlig455_016082 {REF} {Length: 419} {NoTransDecoderORF} {RNA1509_34937} {RNA1310_3298} {RNA815_22311}

Mlig455_041037 {REF} {Length: 2026} {RNA1509_22642} {RNA1310_32012} {RNA815_16629}

Mlig455_051413 {REF} {Length: 3765} {RNA1509_34937, RNA1509_47681} {RNA1310_3298, RNA1509_47681} {RNA1509_47681, RNA815_7759.1}

Mlig455_059417 {REF} {Length: 3670} {RNA1509_34937} {RNA1310_2313.1} {RNA815_7759.1}
30. MligTC455_20864 359 7.49 Mlig455_014815

Neo: -

Age: -

Region-enriched R4: 3.052/0.00599
Region-enriched R5: 2.028/0.03479

 CASP3 0.958 - - - - 0.958 - Mlig455_014815 {REF} {Length: 1932} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=132.7]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=213, Expect=3e-67]; ENSG00000165806, CASP7, caspase 7, [Score=211, Expect=2e-66]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=209, Expect=8e-66]; ENSMUSG00000031628, Casp3, caspase 3, [Score=201, Expect=6e-63]} {Dmel: FBgn0019972, Drice, Death related ICE-like caspase, [Score=185, Expect=4e-56]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=130, Expect=6e-36]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=164, Expect=2e-49]} {RNA1509_27339, RNA1509_8672} {RNA1310_32950.1, RNA1509_27339} {RNA1509_27339, RNA815_12370.1}
31. MligTC455_16373 174 3.63 Mlig455_030616, Mlig455_031025

Neo: -

Age: -

Region-enriched R7: 3.799/0.02098

 RAPGEF2 0.955 - - - - 0.955 -

Mlig455_030616 {REF} {Length: 3142} {Pfam: RasGEF domain [PF00617.21, score=60.1]; RasGEF N-terminal motif [PF00618.22, score=30.4]; Hpt domain [PF01627.25, score=20.8]} {Human: ENSG00000109756, RAPGEF2, Rap guanine nucleotide exchange factor 2, [Score=126, Expect=5e-29]; ENSG00000158987, RAPGEF6, Rap guanine nucleotide exchange factor 6, [Score=121, Expect=1e-27]; ENSG00000273217, AC008695.1, novel protein, [Score=120, Expect=4e-27]} {Mouse: ENSMUSG00000062232, Rapgef2, Rap guanine nucleotide exchange factor (GEF) 2, [Score=125, Expect=6e-29]; ENSMUSG00000037533, Rapgef6, Rap guanine nucleotide exchange factor (GEF) 6, [Score=120, Expect=4e-28]} {Dmel: FBgn0265778, PDZ-GEF, PDZ domain-containing guanine nucleotide exchange factor, [Score=118, Expect=8e-27]} {Celegans: WBGene00004254, pxf-1, Rap guanine nucleotide exchange factor, [Score=114, Expect=9e-26]} {Smed: dd_Smed_v6_10889_0_1, dd_Smed_v6_10889_0_1, [Score=69.3, Expect=5e-12]} {RNA1310_33127.1} {RNA815_32874}

Mlig455_031025 {REF} {Length: 3182} {Pfam: RasGEF domain [PF00617.21, score=58.2]; RasGEF N-terminal motif [PF00618.22, score=30.4]} {Human: ENSG00000109756, RAPGEF2, Rap guanine nucleotide exchange factor 2, [Score=127, Expect=3e-29]; ENSG00000158987, RAPGEF6, Rap guanine nucleotide exchange factor 6, [Score=122, Expect=8e-28]; ENSG00000273217, AC008695.1, novel protein, [Score=121, Expect=2e-27]} {Mouse: ENSMUSG00000062232, Rapgef2, Rap guanine nucleotide exchange factor (GEF) 2, [Score=126, Expect=3e-29]; ENSMUSG00000037533, Rapgef6, Rap guanine nucleotide exchange factor (GEF) 6, [Score=123, Expect=8e-29]} {Dmel: FBgn0265778, PDZ-GEF, PDZ domain-containing guanine nucleotide exchange factor, [Score=120, Expect=2e-27]} {Celegans: WBGene00004254, pxf-1, Rap guanine nucleotide exchange factor, [Score=109, Expect=3e-24]} {Smed: dd_Smed_v6_4950_0_3, dd_Smed_v6_4950_0_3, [Score=72.0, Expect=1e-12]} {RNA1310_33127.1} {RNA815_32874}
32. MligTC455_18447 564 11.74 Mlig455_004573, Mlig455_004576, Mlig455_064768

Neo: -

Age: -

 0.955 - - - - 0.955 -

Mlig455_004573 {REF} {Length: 896} {NoTransDecoderORF} {RNA1310_83095} {RNA815_25848}

Mlig455_004576 {REF} {Length: 708} {NoTransDecoderORF} {RNA1310_83095} {RNA815_25848}

Mlig455_064768 {REF} {Length: 964} {NoTransDecoderORF} {RNA1310_83095} {RNA815_25848}
33. MligTC455_42160 601 12.52 Mlig455_018542, Mlig455_058399

Neo: -

Age: -

 CAPSL 0.955 - - - - 0.955 -

Mlig455_018542 {REF} {Length: 2698} {TRANSSPLICED} {Pfam: EF-hand domain [PF13405.8, score=62.3]; EF hand [PF00036.34, score=56.5]; EF-hand domain pair [PF13499.8, score=55.2]; EF hand [PF13202.8, score=41.0]; EF-hand domain pair [PF13833.8, score=39.8]} {Human: ENSG00000152611, CAPSL, calcyphosine like, [RH, Score=239, Expect=6e-77]} {Mouse: ENSMUSG00000039676, Capsl, calcyphosine-like, [Score=257, Expect=5e-84]} {Dmel: FBgn0051345, CG31345, [Score=190, Expect=5e-58]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=50.8, Expect=2e-07]} {Smed: dd_Smed_v6_7209_0_1, dd_Smed_v6_7209_0_1, [Score=239, Expect=2e-77]} {RNA1509_53428} {RNA1310_21756.3} {RNA815_16758}

Mlig455_058399 {REF} {Length: 1789} {TRANSSPLICED} {Pfam: EF-hand domain [PF13405.8, score=73.0]; EF-hand domain pair [PF13499.8, score=65.7]; EF hand [PF00036.34, score=63.2]; EF hand [PF13202.8, score=50.3]; EF-hand domain pair [PF13833.8, score=44.7]} {Human: ENSG00000152611, CAPSL, calcyphosine like, [RH, Score=270, Expect=2e-92]} {Mouse: ENSMUSG00000039676, Capsl, calcyphosine-like, [RH, Score=279, Expect=5e-96]} {Dmel: FBgn0051345, CG31345, [RH, Score=240, Expect=7e-81]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=63.5, Expect=1e-12]} {Smed: dd_Smed_v6_4512_0_1, dd_Smed_v6_4512_0_1, [RH, Score=289, Expect=5e-100]} {RNA1509_53428, RNA1509_53848} {RNA1310_21756.2, RNA1509_53848} {RNA1509_53848, RNA815_16758}
34. MligTC455_47721 25 0.51 Mlig455_017471

Neo: -

Age: logFC(26M/2M)=0.335

 SLC18B1 0.955 - - - - - 0.955 Mlig455_017471 {REF} {Length: 2642} {Pfam: Major Facilitator Superfamily [PF07690.18, score=151.5]; Sugar (and other) transporter [PF00083.26, score=18.1]} {Human: ENSG00000146409, SLC18B1, solute carrier family 18 member B1, [RH, Score=193, Expect=3e-56]} {Mouse: ENSMUSG00000037455, Slc18b1, solute carrier family 18, subfamily B, member 1, [Score=214, Expect=3e-63]} {Celegans: WBGene00018860, vpat-1, Vesicular PolyAmine Transporter, [Score=227, Expect=4e-68]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [Score=53.9, Expect=1e-07]} {RNA1509_14952} {RNA1310_8790} {RNA815_3189}
35. MligTC455_48074 77 1.61 Mlig455_025063

Neo: -

Age: -

 0.955 - - - - 0.955 - Mlig455_025063 {REF} {Length: 1497} {NoTransDecoderORF} {RNA1509_19361} {RNA1310_62803} {RNA815_14770.1}
36. MligTC455_54020 578 12.05 Mlig455_011514

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.471

 0.955 - - - - 0.955 - Mlig455_011514 {REF} {Length: 6920} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=69.6]; gag-polyprotein putative aspartyl protease [PF13975.8, score=22.4]} {Smed: dd_Smed_v6_16336_0_2, dd_Smed_v6_16336_0_2, [Score=129, Expect=8e-33]} {RNA1509_3668} {RNA1310_1864.1} {RNA815_1730.1}
37. MligTC455_18050 570 11.88 Mlig455_055052

Neo: -

Age: -

 0.954 - - - - 0.954 - Mlig455_055052 {REF} {Length: 950} {Pfam: PLAC8 family [PF04749.19, score=73.5]; Uncharacterized protein conserved in archaea (DUF2180) [PF09947.11, score=18.7]} {Smed: dd_Smed_v6_743_0_1, dd_Smed_v6_743_0_1, [Score=111, Expect=4e-33]} {RNA1509_44969} {RNA1310_55602} {RNA815_30798}
38. MligTC455_34021 125 2.61 Mlig455_039887

Neo: -

Age: -

 0.954 - - - - 0.954 - Mlig455_039887 {REF} {Length: 2575} {TRANSSPLICED} {RNA1509_10624} {RNA1310_1445} {RNA815_405.1}
39. MligTC455_08692 107 2.23 Mlig455_058306, Mlig455_058307, Mlig455_065817

Neo: -

Age: -

 ALKBH3 0.953 - - - - 0.953 -

Mlig455_058306 {REF} {Length: 5928} {Pfam: 2OG-Fe(II) oxygenase superfamily [PF13532.8, score=69.9]} {Human: ENSG00000166199, ALKBH3, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase, [Score=90.9, Expect=1e-19]} {Mouse: ENSMUSG00000040174, Alkbh3, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase, [Score=92.0, Expect=4e-20]} {Smed: dd_Smed_v6_7441_0_1, dd_Smed_v6_7441_0_1, [Score=82.0, Expect=6e-17]} {RNA1310_51047}

Mlig455_058307 {REF} {Length: 228} {NoTransDecoderORF} {RNA1310_102038}

Mlig455_065817 {REF} {Length: 181} {NoTransDecoderORF} {RNA1310_128812}
40. MligTC455_35877 331 6.9 Mlig455_065077

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.663

 0.953 - - - - 0.953 - Mlig455_065077 {REF} {Length: 746} {TRANSSPLICED} {RNA1509_30262} {RNA1310_14575.1} {RNA815_18974}
41. MligTC455_39355 318 6.63 Mlig455_066221

Neo: -

Age: logFC(26M/2M)=-0.462

 0.953 - - - - 0.953 - Mlig455_066221 {REF} {Length: 1502} {Pfam: Sleepless protein [PF17064.7, score=30.6]} {Dmel: FBgn0260499, qvr, quiver, [Score=48.1, Expect=2e-07]} {Smed: dd_Smed_v6_11379_0_1, dd_Smed_v6_11379_0_1, [RH, Score=77.4, Expect=9e-19]} {RNA1509_28973} {RNA1310_56072.1, RNA1509_28973} {RNA1509_28973, RNA815_30549}
42. MligTC455_47180 201 4.18 Mlig455_060479

Neo: -

Age: -

 CTNNB1 0.953 - - - - 0.953 - Mlig455_060479 {REF} {Length: 3957} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=52.6]} {Human: ENSG00000168036, CTNNB1, catenin beta 1, [Score=335, Expect=9e-104]} {Mouse: ENSMUSG00000006932, Ctnnb1, catenin (cadherin associated protein), beta 1, [Score=335, Expect=3e-103]} {Dmel: FBgn0000117, arm, armadillo, [Score=332, Expect=5e-103]} {Celegans: WBGene00001979, hmp-2, Beta-catenin-like protein hmp-2, [Score=154, Expect=4e-39]} {Smed: dd_Smed_v6_4850_0_1, dd_Smed_v6_4850_0_1, [Score=195, Expect=7e-55]} {RNA1509_16403} {RNA1310_6005} {RNA815_6676}
43. MligTC455_12731 331 6.89 Mlig455_005108

Neo: -

Age: -

Region-enriched R6: 3.150/0.01756

 0.952 - - - - 0.952 - Mlig455_005108 {REF} {Length: 654} {NoTransDecoderORF} {RNA1509_44841} {RNA1310_66981} {RNA815_54535}
44. MligTC455_54261 134 2.8 Mlig455_059557

Neo: -

Age: Up-Down-Down

 SLC27A4 0.952 - - - - 0.952 - Mlig455_059557 {REF} {Length: 3920} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=240.8]; AMP-binding enzyme C-terminal domain [PF13193.8, score=30.4]} {Human: ENSG00000167114, SLC27A4, solute carrier family 27 member 4, [RH, Score=640, Expect=0.0]; ENSG00000130304, SLC27A1, solute carrier family 27 member 1, [RH, Score=613, Expect=0.0]} {Mouse: ENSMUSG00000059316, Slc27a4, solute carrier family 27 (fatty acid transporter), member 4, [RH, Score=627, Expect=0.0]; ENSMUSG00000031808, Slc27a1, solute carrier family 27 (fatty acid transporter), member 1, [RH, Score=620, Expect=0.0]} {Dmel: FBgn0267828, Fatp, Fatty acid (long chain) transport protein, [RH, Score=592, Expect=0.0]} {Celegans: WBGene00017012, acs-22, Fatty Acid CoA Synthetase family, [RH, Score=494, Expect=1e-167]} {Smed: dd_Smed_v6_4057_0_1, dd_Smed_v6_4057_0_1, [RH, Score=635, Expect=0.0]} {RNA1509_18148} {RNA1310_5176, RNA1509_18148} {RNA1509_18148, RNA815_3662}
45. MligTC455_38566 68 1.41 Mlig455_014445

Neo: -

Age: -

 CHRNB3 0.95 - - - - 0.950 - Mlig455_014445 {REF} {Length: 1764} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=126.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=56.0]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=139, Expect=5e-36]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=138, Expect=1e-35]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=136, Expect=8e-35]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=136, Expect=8e-35]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=135, Expect=2e-34]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=138, Expect=8e-36]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=136, Expect=6e-35]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=134, Expect=1e-34]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=133, Expect=5e-34]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=143, Expect=3e-37]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=154, Expect=2e-41]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=149, Expect=5e-40]} {RNA1310_19180} {RNA815_21410}

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