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Results for MligTC455_10217

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_10217 100 2.08 Mlig455_042730

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.306/0.02912
Region-enriched R3: 3.318/0.03227

Mlig455_042730 {REF} {Length: 1398} {RNA1509_44180} {RNA1310_20217} {RNA815_8842}

Cumulative graph for MligTC455_10217

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.933 2.036 0.98808 1.00000
RegionR2 4.306 2.036 0.00153 0.02912
RegionR3 3.318 2.036 0.00112 0.03227
RegionR4 -1.602 2.036 0.99788 1.00000
RegionR5 -0.451 2.036 0.93988 1.00000
RegionR6 -1.829 2.036 0.99823 1.00000
RegionR7 1.185 2.036 0.32900 0.96422
RegionR8 -3.993 2.036 0.31189 0.94426

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -3.226 2.036 0.64096 1.00000
RegenerationR2 -2.62 2.036 0.01035 0.16402
RegenerationR3 -2.398 2.036 0.03091 0.31433
RegenerationR4 -2.432 2.036 0.05958 0.39145
RegenerationR5 -2.52 2.036 0.03806 0.32293
RegenerationR6 -2.374 2.036 0.14225 0.46198
RegenerationBL -2.787 2.036 1.00000 1.00000
RegenerationTP -2.236 2.036 1.00000 1.00000


Genes with expression patterns similar to MligTC455_10217

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_10217 100 2.08 Mlig455_042730

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.306/0.02912
Region-enriched R3: 3.318/0.03227

5 1.000 1.000 1.000 - 1.000 1.000 Mlig455_042730 {REF} {Length: 1398} {RNA1509_44180} {RNA1310_20217} {RNA815_8842}
2. MligTC455_53453 949 19.76 Mlig455_032022

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.635

IAH1 1.698 - 0.744 - - 0.954 - Mlig455_032022 {REF} {Length: 1554} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=85.6]; GDSL-like Lipase/Acylhydrolase [PF00657.24, score=35.2]} {Human: ENSG00000134330, IAH1, isoamyl acetate hydrolyzing esterase 1 (putative), [RH, Score=147, Expect=3e-43]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=132, Expect=2e-37]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [RH, Score=152, Expect=8e-46]} {RNA1509_17158} {RNA1310_31040.1, RNA1509_17158} {RNA1509_17158, RNA815_22020}
3. MligTC455_53452 887 18.47 Mlig455_032015

Neo: -

Age: -

Regeneration-downregulated BL: -2.041

Regeneration-depleted BL: -2.041

1.692 - 0.742 - - 0.950 - Mlig455_032015 {REF} {Length: 1210} {Pfam: GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=32.4]} {Mouse: ENSMUSG00000062054, Iah1, isoamyl acetate-hydrolyzing esterase 1 homolog, [Score=58.9, Expect=3e-11]} {Smed: dd_Smed_v6_6241_0_1, dd_Smed_v6_6241_0_1, [Score=89.7, Expect=1e-22]} {RNA1509_17158} {RNA1310_31040.1} {RNA815_22020}
4. MligTC455_41199 7523 156.73 Mlig455_001888, Mlig455_048783

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.793

CFAP45 1.668 - 0.707 - - 0.961 -

Mlig455_001888 {REF} {Length: 2583} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=192.2]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=301, Expect=2e-95]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=296, Expect=2e-93]} {Dmel: FBgn0037162, CG11449, [Score=100, Expect=4e-22]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=407, Expect=1e-136]} {RNA1509_2741} {RNA1310_7881.1} {RNA815_2376.1}

Mlig455_048783 {REF} {Length: 2929} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [RH, Score=371, Expect=6e-122]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [RH, Score=365, Expect=9e-120]} {Dmel: FBgn0037162, CG11449, [RH, Score=116, Expect=2e-27]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [RH, Score=478, Expect=5e-164]} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA1509_455} {RNA1310_7881.1, RNA1509_11068, RNA1509_22358, RNA1509_2741} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA815_2376.1}
5. MligTC455_31649 44 0.93 Mlig455_007325, Mlig455_008077, Mlig455_036688, Mlig455_044932, Mlig455_069853

Neo: -

Age: Up-Down-Down

TRPM3 0.98 - - - - 0.980 -

Mlig455_007325 {REF} {Length: 4316} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=127.7]; Endonuclease-reverse transcriptase [PF14529.8, score=75.9]} {RNA1509_32599} {RNA1310_1582} {RNA815_252.1}

Mlig455_008077 {REF} {Length: 1249} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=137.9]; Ankyrin repeats (many copies) [PF13637.8, score=96.4]; Ankyrin repeat [PF13606.8, score=60.8]; Ankyrin repeats (many copies) [PF13857.8, score=57.2]; Ankyrin repeat [PF00023.32, score=37.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=101, Expect=1e-20]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=103, Expect=2e-21]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=85.9, Expect=3e-16]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.1, Expect=1e-11]} {Smed: dd_Smed_v6_10717_0_1, dd_Smed_v6_10717_0_1, [Score=100, Expect=6e-21]} {RNA1509_45496} {RNA1310_1582} {RNA815_252.3}

Mlig455_036688 {REF} {Length: 698} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=137.9]; Ankyrin repeats (many copies) [PF13637.8, score=96.4]; Ankyrin repeat [PF13606.8, score=60.8]; Ankyrin repeats (many copies) [PF13857.8, score=57.2]; Ankyrin repeat [PF00023.32, score=37.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=101, Expect=1e-20]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=103, Expect=2e-21]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=85.9, Expect=3e-16]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.1, Expect=1e-11]} {Smed: dd_Smed_v6_10717_0_1, dd_Smed_v6_10717_0_1, [Score=100, Expect=6e-21]} {RNA1509_45496} {RNA1310_1582} {RNA815_252.1}

Mlig455_044932 {REF} {Length: 842} {TRANSSPLICED} {Pfam: Endonuclease-reverse transcriptase [PF14529.8, score=77.0]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=18.8]} {RNA1509_45496} {RNA1310_1659} {RNA815_252.3}

Mlig455_069853 {REF} {Length: 5003} {TRANSSPLICED} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=117.8]; Endonuclease-reverse transcriptase [PF14529.8, score=73.1]} {RNA1509_45496} {RNA1310_1582} {RNA815_252.1}
6. MligTC455_52048 1282 26.72 Mlig455_019679

Neo: -

Age: logFC(26M/2M)=-0.701

0.98 - - - - 0.980 - Mlig455_019679 {REF} {Length: 2281} {Pfam: D-arabinono-1,4-lactone oxidase [PF04030.16, score=40.8]; FAD binding domain [PF01565.25, score=27.1]} {Mouse: ENSMUSG00000034450, Gulo, gulonolactone (L-) oxidase, [Score=55.1, Expect=1e-07]} {Smed: dd_Smed_v6_10292_0_1, dd_Smed_v6_10292_0_1, [Score=127, Expect=4e-31]} {RNA1509_25376, RNA1509_2896} {RNA1310_10814, RNA1509_25376} {RNA1509_25376, RNA815_3783}
7. MligTC455_07930 10 0.21 Mlig455_026231

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=2.342

SLC16A2 0.976 - - - - 0.976 - Mlig455_026231 {REF} {Length: 1904} {Pfam: Major Facilitator Superfamily [PF07690.18, score=27.5]; Sugar (and other) transporter [PF00083.26, score=19.9]; Transmembrane secretion effector [PF05977.15, score=17.1]} {Human: ENSG00000147100, SLC16A2, solute carrier family 16 member 2, [Score=73.6, Expect=1e-14]} {Mouse: ENSMUSG00000033965, Slc16a2, solute carrier family 16 (monocarboxylic acid transporters), member 2, [Score=73.6, Expect=8e-15]; ENSMUSG00000019838, Slc16a10, solute carrier family 16 (monocarboxylic acid transporters), member 10, [Score=71.2, Expect=3e-14]} {Dmel: FBgn0001296, kar, karmoisin, [Score=103, Expect=4e-25]} {Celegans: WBGene00010834, mct-3, MonoCarboxylate Transporter family, [Score=57.0, Expect=2e-09]} {Smed: dd_Smed_v6_9402_0_1, dd_Smed_v6_9402_0_1, [Score=53.1, Expect=3e-08]} {RNA1509_13048} {RNA1310_12929} {RNA815_4877.1}
8. MligTC455_17296 134 2.79 Mlig455_037848

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.847

PIGW 0.976 - - - - 0.976 - Mlig455_037848 {REF} {Length: 2875} {Pfam: GWT1 [PF06423.14, score=77.4]} {Human: ENSG00000277161, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=92.4, Expect=4e-19]; ENSG00000275600, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=92.4, Expect=4e-19]} {Mouse: ENSMUSG00000045140, Pigw, phosphatidylinositol glycan anchor biosynthesis, class W, [Score=107, Expect=4e-24]} {Dmel: FBgn0031422, PIG-Wa, Phosphatidylinositol glycan anchor biosynthesis class W a, [Score=117, Expect=4e-28]} {Celegans: WBGene00022447, hpo-20, Phosphatidylinositol-glycan biosynthesis class W protein, [Score=97.1, Expect=4e-21]} {Smed: dd_Smed_v6_14190_0_1, dd_Smed_v6_14190_0_1, [Score=96.3, Expect=3e-21]} {RNA1509_28166} {RNA1310_42427} {RNA815_4044}
9. MligTC455_12658 17 0.34 Mlig455_065480

Neo: -

Age: -

0.975 - - - - 0.975 - Mlig455_065480 {REF} {Length: 2946} {Pfam: Domain of unknown function (DUF4770) [PF15994.7, score=19.0]} {RNA1310_40031.2} {RNA815_52899}
10. MligTC455_16225 212 4.42 Mlig455_019360

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.571

0.971 - - - - 0.971 - Mlig455_019360 {REF} {Length: 2345} {Smed: dd_Smed_v6_16150_0_1, dd_Smed_v6_16150_0_1, [RH, Score=93.2, Expect=5e-20]} {RNA1509_34395} {RNA1310_13154, RNA1509_34395} {RNA1509_34395, RNA815_10500}
11. MligTC455_32993 456 9.49 Mlig455_068821

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.033

Region-enriched R2: 2.892/0.00773
Region-enriched R3: 2.197/0.02773

CFAP46 0.969 - - - - 0.969 - Mlig455_068821 {REF} {Length: 3199} {Human: ENSG00000171811, CFAP46, cilia and flagella associated protein 46, [Score=201, Expect=3e-52]} {Mouse: ENSMUSG00000049571, Cfap46, cilia and flagella associated protein 46, [Score=232, Expect=2e-62]} {Smed: dd_Smed_v6_14103_0_1, dd_Smed_v6_14103_0_1, [Score=238, Expect=6e-65]} {RNA1509_22612} {RNA1310_312.1} {RNA815_3411}
12. MligTC455_32992 490 10.21 Mlig455_038095, Mlig455_038097

Neo: -

Age: -

Region-enriched R2: 2.886/0.00584
Region-enriched R3: 2.133/0.03102

CFAP46 0.968 - - - - 0.968 -

Mlig455_038095 {REF} {Length: 9404} {Human: ENSG00000171811, CFAP46, cilia and flagella associated protein 46, [RH, Score=1014, Expect=0.0]} {Mouse: ENSMUSG00000049571, Cfap46, cilia and flagella associated protein 46, [RH, Score=742, Expect=0.0]} {Smed: dd_Smed_v6_14103_0_1, dd_Smed_v6_14103_0_1, [RH, Score=818, Expect=0.0]} {RNA1509_22612, RNA1509_24033} {RNA1310_152.1, RNA1509_24033} {RNA1509_24033, RNA815_852}

Mlig455_038097 {REF} {Length: 2124} {Pfam: WXXGXW repeat (2 copies) [PF12779.9, score=37.5]} {RNA1509_22612} {RNA1310_53889} {RNA815_852}
13. MligTC455_37838 40 0.83 Mlig455_012885

Neo: -

Age: Up-Down-Down

PKDREJ 0.968 - - - - 0.968 - Mlig455_012885 {REF} {Length: 13341} {Pfam: Polycystin cation channel [PF08016.14, score=221.2]; REJ domain [PF02010.17, score=52.8]; PLAT/LH2 domain [PF01477.25, score=27.5]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=184, Expect=7e-46]} {Mouse: ENSMUSG00000052496, Pkdrej, polycystin (PKD) family receptor for egg jelly, [Score=186, Expect=7e-47]; ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=178, Expect=3e-44]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=110, Expect=6e-24]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=121, Expect=3e-27]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=260, Expect=1e-69]} {RNA1509_38015} {RNA1310_23208, RNA1509_38015} {RNA1509_38015, RNA815_31966}
14. MligTC455_40202 595 12.39 Mlig455_057253

Neo: -

Age: logFC(26M/2M)=-0.440

DCLK3 0.968 - - - - 0.968 - Mlig455_057253 {REF} {Length: 4012} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.9]; Fungal protein kinase [PF17667.3, score=25.3]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.9]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=371, Expect=1e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=2e-113]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=370, Expect=1e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=296, Expect=6e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=352, Expect=1e-105]} {RNA1509_13597, RNA1509_49808} {RNA1310_2158.1, RNA1509_13597, RNA1509_49808} {RNA1509_13597, RNA1509_49808, RNA815_2598}
15. MligTC455_05581 42 0.87 Mlig455_005887

Neo: -

Age: -

0.967 - - - - 0.967 - Mlig455_005887 {REF} {Length: 906} {NoTransDecoderORF}
16. MligTC455_46366 186 3.88 Mlig455_058774

Neo: -

Age: -

0.967 - - - - 0.967 - Mlig455_058774 {REF} {Length: 1243} {NoTransDecoderORF} {RNA1509_27726} {RNA1310_29978} {RNA815_47137}
17. MligTC455_40756 35 0.73 Mlig455_050356, Mlig455_065112

Neo: -

Age: -

0.966 - - - - 0.966 -

Mlig455_050356 {REF} {Length: 740} {NoTransDecoderORF} {RNA1509_38191} {RNA1310_5321.1} {RNA815_14836}

Mlig455_065112 {REF} {Length: 277} {NoTransDecoderORF} {RNA1509_38191} {RNA1310_5321.1} {RNA815_14836}
18. MligTC455_08795 29 0.6 Mlig455_005761

Neo: -

Age: Down-Up-Down

0.965 - - - - 0.965 - Mlig455_005761 {REF} {Length: 855} {NoTransDecoderORF} {RNA1509_57252} {RNA1310_97275.1} {RNA815_50075}
19. MligTC455_55615 9 0.18 Mlig455_002937

Neo: -

Age: -

0.965 - - - - 0.965 - Mlig455_002937 {REF} {Length: 373} {NoTransDecoderORF}
20. MligTC455_39518 40 0.83 Mlig455_031401

Neo: -

Age: -

CHRNA1 0.964 - - - - 0.964 - Mlig455_031401 {REF} {Length: 2411} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=92.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=76.4]} {Human: ENSG00000138435, CHRNA1, cholinergic receptor nicotinic alpha 1 subunit, [Score=120, Expect=3e-29]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=120, Expect=2e-29]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=115, Expect=2e-27]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=114, Expect=3e-27]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=134, Expect=2e-34]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=135, Expect=1e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=124, Expect=5e-31]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=114, Expect=2e-27]} {RNA1509_53098} {RNA1310_67430} {RNA815_23438}
21. MligTC455_18534 164 3.42 Mlig455_013039

Neo: -

Age: -

CD163L1 0.963 - - - - 0.963 - Mlig455_013039 {REF} {Length: 1954} {Pfam: Scavenger receptor cysteine-rich domain [PF00530.20, score=87.2]; Scavenger receptor cysteine-rich domain [PF15494.8, score=29.1]} {Human: ENSG00000177675, CD163L1, CD163 molecule like 1, [Score=96.3, Expect=1e-21]} {Mouse: ENSMUSG00000047517, Dmbt1, deleted in malignant brain tumors 1, [Score=80.1, Expect=2e-16]; ENSMUSG00000006204, 5430419D17Rik, RIKEN cDNA 5430419D17 gene, [Score=79.0, Expect=5e-16]; ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=78.6, Expect=6e-16]; ENSMUSG00000025185, Loxl4, lysyl oxidase-like 4, [Score=78.2, Expect=9e-16]; ENSMUSG00000029699, Ssc4d, scavenger receptor cysteine rich family, 4 domains, [Score=76.3, Expect=4e-15]} {Dmel: FBgn0034660, lox2, lysyl oxidase-like 2, [Score=89.4, Expect=9e-20]} {Smed: dd_Smed_v6_10591_0_1, dd_Smed_v6_10591_0_1, [Score=89.7, Expect=4e-20]} {RNA1509_21249} {RNA1310_15268.1} {RNA815_5714}
22. MligTC455_29740 15 0.32 Mlig455_001115

Neo: -

Age: -

SLC5A8 0.963 - - - - 0.963 - Mlig455_001115 {REF} {Length: 1813} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=94.4]; Sodium:solute symporter family [PF00474.19, score=44.7]} {Human: ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=195, Expect=2e-53]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=195, Expect=2e-53]; ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=190, Expect=1e-51]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=194, Expect=2e-53]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=192, Expect=9e-53]} {Dmel: FBgn0034494, CG10444, [Score=162, Expect=2e-42]} {Celegans: WBGene00018716, F52H2.4, [Score=106, Expect=4e-24]} {Smed: dd_Smed_v6_13771_0_1, dd_Smed_v6_13771_0_1, [Score=162, Expect=2e-42]} {RNA1310_73267} {RNA815_24869}
23. MligTC455_40201 607 12.65 Mlig455_052028

Neo: -

Age: logFC(26M/2M)=-0.526

DCLK3 0.963 - - - - 0.963 - Mlig455_052028 {REF} {Length: 3990} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.8]; Fungal protein kinase [PF17667.3, score=26.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.0]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=370, Expect=2e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=8e-110]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=369, Expect=3e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=295, Expect=7e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=351, Expect=2e-105]} {RNA1509_13597} {RNA1310_2158.1} {RNA815_2598}
24. MligTC455_17315 129 2.69 Mlig455_065409

Neo: -

Age: Up-Down-Down

0.96 - - - - 0.960 - Mlig455_065409 {REF} {Length: 9465} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF3883) [PF13020.8, score=40.0]} {Smed: dd_Smed_v6_10250_0_1, dd_Smed_v6_10250_0_1, [RH, Score=197, Expect=4e-50]} {RNA1509_10371} {RNA1310_1171} {RNA815_5724}
25. MligTC455_41305 52 1.08 Mlig455_045937

Neo: -

Age: -

RBM38 0.96 - - - - - 0.960 Mlig455_045937 {REF} {Length: 2092} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=57.4]} {Human: ENSG00000132819, RBM38, RNA binding motif protein 38, [Score=136, Expect=1e-38]; ENSG00000112183, RBM24, RNA binding motif protein 24, [Score=135, Expect=2e-38]} {Mouse: ENSMUSG00000038132, Rbm24, RNA binding motif protein 24, [Score=134, Expect=5e-38]; ENSMUSG00000027510, Rbm38, RNA binding motif protein 38, [Score=132, Expect=3e-37]} {Dmel: FBgn0260943, Rbp6, RNA-binding protein 6, [Score=74.7, Expect=6e-15]} {Celegans: WBGene00006321, sup-12, SUPpressor, [Score=132, Expect=9e-39]} {Smed: dd_Smed_v6_11304_0_1, dd_Smed_v6_11304_0_1, [Score=159, Expect=2e-47]} {RNA1310_47322} {RNA815_37890}
26. MligTC455_24711 46 0.96 Mlig455_015705

Neo: -

Age: -

Regeneration-upregulated BL: 6.967

Regeneration-enriched BL: 6.967

0.959 - - - - 0.959 - Mlig455_015705 {REF} {Length: 1380} {NoTransDecoderORF} {RNA1509_40708} {RNA1310_77515} {RNA815_26884}
27. MligTC455_36097 2740 57.08 Mlig455_040117, Mlig455_067335

Neo: -

Age: -

ANKDD1A 0.959 - - - - 0.959 -

Mlig455_040117 {REF} {Length: 2659} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=188.9]; Ankyrin repeats (many copies) [PF13637.8, score=157.3]; Ankyrin repeats (many copies) [PF13857.8, score=149.0]; Ankyrin repeat [PF13606.8, score=142.1]; Ankyrin repeat [PF00023.32, score=132.4]; Death domain [PF00531.24, score=24.1]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [Score=228, Expect=9e-67]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [Score=241, Expect=8e-72]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=138, Expect=1e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=135, Expect=9e-33]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=456, Expect=2e-154]} {RNA1509_19327} {RNA1310_8321.1, RNA1509_19327} {RNA1509_19327, RNA815_4521.1}

Mlig455_067335 {REF} {Length: 2660} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=188.4]; Ankyrin repeats (many copies) [PF13637.8, score=155.8]; Ankyrin repeats (many copies) [PF13857.8, score=148.9]; Ankyrin repeat [PF13606.8, score=140.8]; Ankyrin repeat [PF00023.32, score=132.9]; Death domain [PF00531.24, score=24.1]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [Score=228, Expect=1e-66]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [Score=241, Expect=8e-72]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=137, Expect=2e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=135, Expect=8e-33]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=456, Expect=2e-154]} {RNA1509_19327} {RNA1310_8321.1} {RNA815_4521.1}
28. MligTC455_53484 40 0.82 Mlig455_036835

Neo: -

Age: Down-Up-Down

0.959 - - - - 0.959 - Mlig455_036835 {REF} {Length: 1128} {RNA1509_45864} {RNA1310_3774, RNA1509_45864} {RNA1509_45864, RNA815_2602}
29. MligTC455_19702 266 5.54 Mlig455_012020

Neo: -

Age: -

TTC30B 0.958 - - - - 0.958 - Mlig455_012020 {REF} {Length: 2634} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF14559.8, score=73.1]; Tetratricopeptide repeat [PF07719.19, score=53.4]; Tetratricopeptide repeat [PF13424.8, score=39.7]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=38.5]; Tetratricopeptide repeat [PF13432.8, score=37.3]; Tetratricopeptide repeat [PF13174.8, score=31.6]; Tetratricopeptide repeat [PF00515.30, score=27.1]; Tetratricopeptide repeat [PF13428.8, score=26.0]; Tetratricopeptide repeat [PF13181.8, score=25.9]; Tetratricopeptide repeat [PF13176.8, score=21.7]; Tetratricopeptide repeat [PF13371.8, score=20.6]; Outer membrane lipoprotein [PF13525.8, score=20.3]; Putative TPR-like repeat [PF17004.7, score=20.1]} {Human: ENSG00000196659, TTC30B, tetratricopeptide repeat domain 30B, [Score=778, Expect=0.0]; ENSG00000197557, TTC30A, tetratricopeptide repeat domain 30A, [Score=771, Expect=0.0]} {Mouse: ENSMUSG00000075271, Ttc30a1, tetratricopeptide repeat domain 30A1, [Score=778, Expect=0.0]; ENSMUSG00000075273, Ttc30b, tetratricopeptide repeat domain 30B, [Score=778, Expect=0.0]; ENSMUSG00000075272, Ttc30a2, tetratricopeptide repeat domain 30A2, [Score=774, Expect=0.0]} {Dmel: FBgn0032470, CG5142, [Score=515, Expect=1e-175]} {Celegans: WBGene00001117, dyf-1, Tetratricopeptide repeat protein 30 homolog, [Score=568, Expect=0.0]} {Smed: dd_Smed_v6_8798_0_1, dd_Smed_v6_8798_0_1, [Score=865, Expect=0.0]} {RNA1509_12977} {RNA1310_15403, RNA1509_12977} {RNA1509_12977, RNA815_4297}
30. MligTC455_34747 2468 51.41 Mlig455_012139, Mlig455_028961

Neo: -

Age: logFC(26M/2M)=1.937

ELF1, ELK1 0.958 - - - - 0.958 -

Mlig455_012139 {REF} {Length: 2138} {Pfam: Ets-domain [PF00178.24, score=59.0]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=20.6]} {Human: ENSG00000126767, ELK1, ELK1, ETS transcription factor, [Score=51.6, Expect=1e-06]; ENSG00000120690, ELF1, E74 like ETS transcription factor 1, [Score=51.6, Expect=2e-06]; ENSG00000134954, ETS1, ETS proto-oncogene 1, transcription factor, [Score=50.1, Expect=2e-06]; ENSG00000157557, ETS2, ETS proto-oncogene 2, transcription factor, [Score=50.1, Expect=6e-06]; ENSG00000105672, ETV2, ETS variant 2, [Score=49.3, Expect=4e-06]; ENSG00000124664, SPDEF, SAM pointed domain containing ETS transcription factor, [Score=49.3, Expect=7e-06]} {Mouse: ENSMUSG00000009406, Elk1, ELK1, member of ETS oncogene family, [Score=52.4, Expect=7e-07]; ENSMUSG00000036461, Elf1, E74-like factor 1, [Score=51.2, Expect=2e-06]; ENSMUSG00000032035, Ets1, E26 avian leukemia oncogene 1, 5' domain, [Score=50.1, Expect=3e-06]} {Dmel: FBgn0000567, Eip74EF, Ecdysone-induced protein 74EF, [Score=50.8, Expect=2e-06]} {Celegans: WBGene00016029, elf-1, See eff, [Score=48.1, Expect=7e-06]} {Smed: dd_Smed_v6_7247_0_1, dd_Smed_v6_7247_0_1, [RH, Score=70.9, Expect=2e-13]} {RNA1509_4244} {RNA1310_14259.1, RNA1509_4244} {RNA1509_4244, RNA815_2480.2}

Mlig455_028961 {REF} {Length: 2107} {Pfam: Ets-domain [PF00178.24, score=56.4]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.0]} {Human: ENSG00000120690, ELF1, E74 like ETS transcription factor 1, [Score=50.4, Expect=4e-06]; ENSG00000126767, ELK1, ELK1, ETS transcription factor, [Score=49.7, Expect=6e-06]} {Mouse: ENSMUSG00000036461, Elf1, E74-like factor 1, [Score=50.1, Expect=4e-06]; ENSMUSG00000009406, Elk1, ELK1, member of ETS oncogene family, [Score=50.1, Expect=3e-06]; ENSMUSG00000030199, Etv6, ets variant 6, [Score=48.5, Expect=9e-06]} {Dmel: FBgn0000567, Eip74EF, Ecdysone-induced protein 74EF, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_7247_0_1, dd_Smed_v6_7247_0_1, [RH, Score=71.6, Expect=8e-14]} {RNA1509_4244} {RNA1310_14259.1} {RNA815_2480.2}
31. MligTC455_09472 23 0.47 Mlig455_059329

Neo: -

Age: -

NGB 0.956 - - - - 0.956 - Mlig455_059329 {REF} {Length: 2110} {Pfam: Globin [PF00042.24, score=52.9]} {Human: ENSG00000165553, NGB, neuroglobin, [RH, Score=48.5, Expect=8e-07]} {Mouse: ENSMUSG00000021032, Ngb, neuroglobin, [RH, Score=50.4, Expect=1e-07]} {RNA1310_93460} {RNA815_18392}
32. MligTC455_21721 1177 24.51 Mlig455_052943, Mlig455_053013

Neo: -

Age: -

TRPM3 0.956 - - - - 0.956 -

Mlig455_052943 {REF} {Length: 4423} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.0]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=52.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=521, Expect=2e-158]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=522, Expect=1e-158]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=484, Expect=1e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=362, Expect=8e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=607, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}

Mlig455_053013 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.1]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=53.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=8e-157]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=519, Expect=2e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=8e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=605, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1, RNA1509_4847} {RNA1509_4847, RNA815_652.1}
33. MligTC455_26873 68 1.42 Mlig455_027780

Neo: -

Age: Up-Down-Down

0.955 - - - - 0.955 - Mlig455_027780 {REF} {Length: 2483} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=41.6]} {Smed: dd_Smed_v6_9242_0_1, dd_Smed_v6_9242_0_1, [Score=119, Expect=3e-28]} {RNA1509_39812} {RNA1310_27043.1} {RNA815_21476}
34. MligTC455_39101 80 1.67 Mlig455_009466

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_009466 {REF} {Length: 363} {NoTransDecoderORF} {RNA1509_29120} {RNA1310_73330} {RNA815_29655.2}
35. MligTC455_45892 26 0.54 Mlig455_024234

Neo: -

Age: -

HTR3A 0.955 - - - - 0.955 - Mlig455_024234 {REF} {Length: 1801} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=107.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=139, Expect=6e-36]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=137, Expect=3e-35]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=135, Expect=1e-34]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=137, Expect=1e-35]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=136, Expect=4e-35]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=134, Expect=2e-34]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=122, Expect=5e-30]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=140, Expect=2e-36]} {Smed: dd_Smed_v6_12182_0_1, dd_Smed_v6_12182_0_1, [Score=130, Expect=3e-33]} {RNA1509_7752} {RNA1310_10606.2} {RNA815_50031}
36. MligTC455_43474 102 2.12 Mlig455_003702

Neo: -

Age: -

0.952 - - - - 0.952 - Mlig455_003702 {REF} {Length: 428} {NoTransDecoderORF} {RNA1509_9116} {RNA1310_43705} {RNA815_26628}
37. MligTC455_48617 1098 22.87 Mlig455_045679

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.603

Region-enriched R2: 1.287/0.04140
Region-enriched R4: 1.125/0.04806

CCDC81 0.952 - - - - 0.952 - Mlig455_045679 {REF} {Length: 3799} {Human: ENSG00000149201, CCDC81, coiled-coil domain containing 81, [RH, Score=239, Expect=1e-70]} {Mouse: ENSMUSG00000039391, Ccdc81, coiled-coil domain containing 81, [Score=215, Expect=9e-61]} {Smed: dd_Smed_v6_6753_0_1, dd_Smed_v6_6753_0_1, [RH, Score=378, Expect=3e-122]} {RNA1509_2273} {RNA1310_2252} {RNA815_610}
38. MligTC455_09829 23 0.49 Mlig455_020089

Neo: -

Age: Down-Up-Down

0.951 - - - - 0.951 - Mlig455_020089 {REF} {Length: 2399} {TRANSSPLICED} {RNA1310_22138} {RNA815_46507}
39. MligTC455_45832 434 9.04 Mlig455_031218

Neo: -

Age: logFC(26M/2M)=-0.554

Regeneration-depleted BL: -8.141
Regeneration-depleted R5: -5.539
Regeneration-depleted R6: -4.514
Regeneration-depleted R4: -4.459
Regeneration-depleted R3: -3.400
Regeneration-depleted R2: -2.225

CYP2J2 0.951 - - - - 0.951 - Mlig455_031218 {REF} {Length: 2567} {Pfam: Cytochrome P450 [PF00067.24, score=269.5]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=231, Expect=5e-69]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=231, Expect=4e-69]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=229, Expect=2e-68]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=226, Expect=8e-67]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=226, Expect=8e-67]} {Dmel: FBgn0036910, Cyp305a1, [Score=166, Expect=7e-45]} {Celegans: WBGene00012448, cyp-33D3, CYtochrome P450 family, [Score=208, Expect=9e-61]} {Smed: dd_Smed_v6_8600_0_1, dd_Smed_v6_8600_0_1, [Score=221, Expect=1e-65]} {RNA1509_10802} {RNA1310_15759, RNA1509_10802} {RNA1509_10802, RNA815_10494}
40. MligTC455_48923 498 10.38 Mlig455_032490

Neo: -

Age: logFC(26M/2M)=-0.394

IQCH 0.951 - - - - 0.951 - Mlig455_032490 {REF} {Length: 3574} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=26.0]} {Human: ENSG00000103599, IQCH, IQ motif containing H, [Score=594, Expect=0.0]} {Mouse: ENSMUSG00000037801, Iqch, IQ motif containing H, [Score=586, Expect=0.0]} {Smed: dd_Smed_v6_10544_0_1, dd_Smed_v6_10544_0_1, [Score=671, Expect=0.0]} {RNA1509_7338} {RNA1310_3995, RNA1509_7338} {RNA1509_7338, RNA815_1179}
41. MligTC455_07608 80 1.67 Mlig455_005352

Neo: -

Age: logFC(26M/2M)=0.394

Region-enriched R3: 5.990/0.00000

PNLIP 0.95 - - - - - 0.950 Mlig455_005352 {REF} {Length: 2323} {Pfam: Lipase [PF00151.21, score=318.0]} {Human: ENSG00000175535, PNLIP, pancreatic lipase, [RH, Score=271, Expect=6e-85]} {Mouse: ENSMUSG00000025091, Pnliprp2, pancreatic lipase-related protein 2, [RH, Score=288, Expect=2e-91]; ENSMUSG00000046008, Pnlip, pancreatic lipase, [RH, Score=283, Expect=1e-89]} {Dmel: FBgn0029831, CG5966, [RH, Score=229, Expect=2e-68]} {RNA1509_28080} {RNA1310_1779} {RNA815_6964}
42. MligTC455_18684 442 9.2 Mlig455_048930, Mlig455_048954

Neo: -

Age: Down-Up-Up

MAP3K3 0.95 - - - - 0.950 -

Mlig455_048930 {REF} {Length: 1361} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=182.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=127.3]; ABC1 atypical kinase-like domain [PF03109.18, score=21.7]; PB1 domain [PF00564.26, score=19.1]} {Human: ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=229, Expect=2e-68]} {Mouse: ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=228, Expect=3e-68]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=155, Expect=2e-41]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=154, Expect=5e-41]} {Smed: dd_Smed_v6_9266_0_1, dd_Smed_v6_9266_0_1, [Score=196, Expect=4e-57]} {RNA1509_27897} {RNA1310_25374} {RNA815_11066}

Mlig455_048954 {REF} {Length: 1360} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=37.5]; PB1 domain [PF00564.26, score=20.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=18.3]} {Human: ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=81.3, Expect=4e-17]; ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [Score=79.0, Expect=2e-16]} {Mouse: ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=81.3, Expect=3e-17]; ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [Score=78.2, Expect=2e-16]} {RNA1509_27897} {RNA1310_25374} {RNA815_11066}
43. MligTC455_27466 46 0.96 Mlig455_013603

Neo: -

Age: -

Region-enriched R4: 4.655/0.02538

MAP3K19 0.95 - - - - 0.950 - Mlig455_013603 {REF} {Length: 4965} {Pfam: Protein kinase domain [PF00069.27, score=191.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=142.0]; Ankyrin repeats (many copies) [PF13637.8, score=91.0]; Ankyrin repeats (3 copies) [PF12796.9, score=81.0]; Ankyrin repeats (many copies) [PF13857.8, score=53.3]; Ankyrin repeat [PF13606.8, score=37.2]; ABC1 atypical kinase-like domain [PF03109.18, score=23.3]; Fungal protein kinase [PF17667.3, score=22.8]; Ankyrin repeat [PF00023.32, score=21.5]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=162, Expect=4e-40]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=164, Expect=7e-41]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=140, Expect=2e-34]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=132, Expect=7e-32]} {Smed: dd_Smed_v6_2030_0_14, dd_Smed_v6_2030_0_14, [Score=132, Expect=4e-33]} {RNA1509_34593} {RNA1310_13664} {RNA815_7939.1}

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