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Results for MligTC455_32992

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_32992 490 10.21 Mlig455_038095, Mlig455_038097

Neo: -

Age: -

Region-enriched R2: 2.886/0.00584
Region-enriched R3: 2.133/0.03102

 CFAP46

Mlig455_038095 {REF} {Length: 9404} {Human: ENSG00000171811, CFAP46, cilia and flagella associated protein 46, [RH, Score=1014, Expect=0.0]} {Mouse: ENSMUSG00000049571, Cfap46, cilia and flagella associated protein 46, [RH, Score=742, Expect=0.0]} {Smed: dd_Smed_v6_14103_0_1, dd_Smed_v6_14103_0_1, [RH, Score=818, Expect=0.0]} {RNA1509_22612, RNA1509_24033} {RNA1310_152.1, RNA1509_24033} {RNA1509_24033, RNA815_852}

Mlig455_038097 {REF} {Length: 2124} {Pfam: WXXGXW repeat (2 copies) [PF12779.9, score=37.5]} {RNA1509_22612} {RNA1310_53889} {RNA815_852}

Cumulative graph for MligTC455_32992

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.012 3.831 0.14792 0.76159
RegionR2 2.886 3.831 0.00016 0.00584
RegionR3 2.133 3.831 0.00106 0.03102
RegionR4 0.843 3.831 0.36896 0.69216
RegionR5 0.673 3.831 0.43654 0.79657
RegionR6 1.418 3.831 0.06731 0.48497
RegionR7 -1.165 3.831 0.99176 1.00000
RegionR8 -0.776 3.831 0.97823 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 6.022 3.831 0.21386 0.95150
RegenerationR2 0.903 3.831 0.01813 0.22074
RegenerationR3 0.307 3.831 0.52413 0.86876
RegenerationR4 0.557 3.831 0.30489 0.74655
RegenerationR5 0.568 3.831 0.22924 0.66379
RegenerationR6 -0.152 3.831 0.76922 0.96156
RegenerationBL 1.564 3.831 0.04561 0.24457
RegenerationTP 1.173 3.831 0.27952 0.72689


Genes with expression patterns similar to MligTC455_32992

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_32992 490 10.21 Mlig455_038095, Mlig455_038097

Neo: -

Age: -

Region-enriched R2: 2.886/0.00584
Region-enriched R3: 2.133/0.03102

 CFAP46 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_038095 {REF} {Length: 9404} {Human: ENSG00000171811, CFAP46, cilia and flagella associated protein 46, [RH, Score=1014, Expect=0.0]} {Mouse: ENSMUSG00000049571, Cfap46, cilia and flagella associated protein 46, [RH, Score=742, Expect=0.0]} {Smed: dd_Smed_v6_14103_0_1, dd_Smed_v6_14103_0_1, [RH, Score=818, Expect=0.0]} {RNA1509_22612, RNA1509_24033} {RNA1310_152.1, RNA1509_24033} {RNA1509_24033, RNA815_852}

Mlig455_038097 {REF} {Length: 2124} {Pfam: WXXGXW repeat (2 copies) [PF12779.9, score=37.5]} {RNA1509_22612} {RNA1310_53889} {RNA815_852}
2. MligTC455_32993 456 9.49 Mlig455_068821

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.033

Region-enriched R2: 2.892/0.00773
Region-enriched R3: 2.197/0.02773

 CFAP46 5.968 0.994 0.992 1.000 0.988 0.995 0.999 Mlig455_068821 {REF} {Length: 3199} {Human: ENSG00000171811, CFAP46, cilia and flagella associated protein 46, [Score=201, Expect=3e-52]} {Mouse: ENSMUSG00000049571, Cfap46, cilia and flagella associated protein 46, [Score=232, Expect=2e-62]} {Smed: dd_Smed_v6_14103_0_1, dd_Smed_v6_14103_0_1, [Score=238, Expect=6e-65]} {RNA1509_22612} {RNA1310_312.1} {RNA815_3411}
3. MligTC455_41199 7523 156.73 Mlig455_001888, Mlig455_048783

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.793

 CFAP45 4.124 0.710 0.761 0.839 - 0.967 0.847

Mlig455_001888 {REF} {Length: 2583} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=192.2]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=301, Expect=2e-95]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=296, Expect=2e-93]} {Dmel: FBgn0037162, CG11449, [Score=100, Expect=4e-22]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=407, Expect=1e-136]} {RNA1509_2741} {RNA1310_7881.1} {RNA815_2376.1}

Mlig455_048783 {REF} {Length: 2929} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [RH, Score=371, Expect=6e-122]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [RH, Score=365, Expect=9e-120]} {Dmel: FBgn0037162, CG11449, [RH, Score=116, Expect=2e-27]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [RH, Score=478, Expect=5e-164]} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA1509_455} {RNA1310_7881.1, RNA1509_11068, RNA1509_22358, RNA1509_2741} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA815_2376.1}
4. MligTC455_45245 945 19.69 Mlig455_020601

Neo: -

Age: -

 SPAG16 3.986 0.950 0.752 0.815 - 0.745 0.724 Mlig455_020601 {REF} {Length: 1546} {Pfam: WD domain, G-beta repeat [PF00400.34, score=85.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.9]} {Human: ENSG00000144451, SPAG16, sperm associated antigen 16, [Score=163, Expect=1e-43]} {Mouse: ENSMUSG00000053153, Spag16, sperm associated antigen 16, [Score=164, Expect=7e-44]} {Dmel: FBgn0036354, Poc1, Proteome of centrioles 1, [Score=73.9, Expect=5e-14]} {Celegans: WBGene00007972, prp-4, Yeast PRP (Splicing factor) related, [Score=73.2, Expect=1e-13]} {Smed: dd_Smed_v6_6137_0_1, dd_Smed_v6_6137_0_1, [Score=206, Expect=6e-60]} {RNA1509_41329} {RNA1310_9669.1} {RNA815_12897}
5. MligTC455_24001 531 11.07 Mlig455_036318

Neo: -

Age: Up-Down-Down

 DNAH3 3.472 - - 0.807 0.817 0.892 0.956 Mlig455_036318 {REF} {Length: 13102} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=527.0]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=479.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=409.8]; P-loop containing dynein motor region D4 [PF12780.9, score=366.0]; ATP-binding dynein motor region [PF12781.9, score=303.3]; P-loop containing dynein motor region [PF12775.9, score=274.8]; Dynein heavy chain AAA lid domain [PF18198.3, score=187.8]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=157.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=124.6]; Microtubule-binding stalk of dynein motor [PF12777.9, score=124.5]; AAA+ lid domain [PF17857.3, score=66.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=64.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=29.9]; AAA ATPase domain [PF13191.8, score=20.6]; RNA helicase [PF00910.24, score=20.1]} {Human: ENSG00000158486, DNAH3, dynein axonemal heavy chain 3, [RH, Score=5014, Expect=0.0]} {Mouse: ENSMUSG00000052273, Dnah3, dynein, axonemal, heavy chain 3, [RH, Score=5030, Expect=0.0]} {Dmel: FBgn0035581, Dnah3, dynein, axonemal, heavy chain 3, [RH, Score=3534, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=699, Expect=0.0]} {Smed: dd_Smed_v6_6941_0_1, dd_Smed_v6_6941_0_1, [Score=3807, Expect=0.0]} {RNA1509_389} {RNA1310_53.1} {RNA815_33.1}
6. MligTC455_38105 2374 49.46 Mlig455_015942

Neo: -

Age: logFC(26M/2M)=-0.373

 AK9 3.391 - 0.749 0.767 0.891 0.984 - Mlig455_015942 {REF} {Length: 6588} {Pfam: Adenylate kinase [PF00406.24, score=148.4]; AAA domain [PF13207.8, score=69.1]; Domain of unknown function [PF12018.10, score=55.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=38.2]; AAA domain [PF13238.8, score=35.5]; YHS domain [PF04945.15, score=34.7]; AAA domain [PF13479.8, score=31.0]; AAA domain [PF13671.8, score=30.4]; AAA domain [PF13401.8, score=23.9]; Hydin Adenylate kinase-like domain [PF17213.5, score=21.5]; RNA helicase [PF00910.24, score=19.7]; AAA domain [PF13521.8, score=19.6]} {Human: ENSG00000155085, AK9, adenylate kinase 9, [RH, Score=1089, Expect=0.0]} {Mouse: ENSMUSG00000091415, Ak9, adenylate kinase 9, [RH, Score=1080, Expect=0.0]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=54.3, Expect=2e-07]} {Celegans: WBGene00009575, F40F8.1, UMP-CMP kinase 2, [Score=58.9, Expect=3e-09]} {Smed: dd_Smed_v6_9617_0_1, dd_Smed_v6_9617_0_1, [RH, Score=863, Expect=0.0]} {RNA1509_1039} {RNA1310_346} {RNA815_505}
7. MligTC455_43002 147 3.07 Mlig455_004304

Neo: -

Age: Up-Down-Down

 GLUD1 2.713 - - 0.983 0.889 0.841 - Mlig455_004304 {REF} {Length: 2088} {Pfam: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=134.8]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=288, Expect=8e-94]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=285, Expect=5e-93]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=288, Expect=5e-94]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=288, Expect=2e-96]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=240, Expect=4e-76]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=277, Expect=1e-90]} {RNA1509_18938, RNA1509_30743} {RNA1310_2661.2, RNA1509_18938} {RNA1509_18938, RNA815_713.2}
8. MligTC455_43476 4089 85.19 Mlig455_041367

Neo: -

Age: logFC(26M/2M)=-0.284

 TNNC1 2.625 - - - 0.953 0.875 0.797 Mlig455_041367 {REF} {Length: 1848} {Pfam: EF-hand domain pair [PF13499.8, score=49.6]; EF hand [PF00036.34, score=48.0]; EF-hand domain [PF13405.8, score=41.5]; EF hand [PF13202.8, score=41.4]; EF-hand domain pair [PF13833.8, score=29.7]} {Human: ENSG00000114854, TNNC1, troponin C1, slow skeletal and cardiac type, [Score=50.4, Expect=7e-07]; ENSG00000143933, CALM2, calmodulin 2, [Score=49.3, Expect=2e-06]; ENSG00000198668, CALM1, calmodulin 1, [Score=48.9, Expect=2e-06]; ENSG00000160014, CALM3, calmodulin 3, [Score=48.9, Expect=2e-06]} {Mouse: ENSMUSG00000027422, Rrbp1, ribosome binding protein 1, [Score=55.5, Expect=1e-07]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=54.7, Expect=2e-08]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=47.8, Expect=9e-07]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=48.1, Expect=1e-06]} {RNA1509_2843, RNA1509_31377, RNA1509_7835} {RNA1310_12201, RNA1509_2843, RNA1509_31377, RNA1509_7835} {RNA1509_2843, RNA1509_31377, RNA1509_7835, RNA815_6659.1}
9. MligTC455_41200 1715 35.72 Mlig455_069721

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.691

 CFAP45 2.609 - 0.740 - 0.917 0.952 - Mlig455_069721 {REF} {Length: 2678} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=327, Expect=2e-105]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=317, Expect=1e-101]} {Dmel: FBgn0037162, CG11449, [RH, Score=114, Expect=1e-26]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=434, Expect=4e-147]} {RNA1509_11293, RNA1509_455, RNA1509_48510, RNA1509_5508} {RNA1310_7881.1, RNA1509_11293, RNA1509_48510, RNA1509_5508} {RNA1509_11293, RNA1509_48510, RNA1509_5508, RNA815_2376.1}
10. MligTC455_28843 310 6.45 Mlig455_020145

Neo: -

Age: Down-Up-Down

 2.588 - - - 0.893 0.740 0.955 Mlig455_020145 {REF} {Length: 838} {RNA1509_57120} {RNA1310_47368} {RNA815_25285.1}
11. MligTC455_34365 761 15.86 Mlig455_045898

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.155

 2.588 - - - 0.925 0.954 0.709 Mlig455_045898 {REF} {Length: 1534} {RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1310_33460, RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1509_18388, RNA1509_36026, RNA1509_43852, RNA815_35266}
12. MligTC455_18106 1217 25.35 Mlig455_066402

Neo: -

Age: -

 C7orf31 2.58 - - 0.743 0.957 0.880 - Mlig455_066402 {REF} {Length: 3205} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4555) [PF15093.8, score=102.0]} {Human: ENSG00000153790, C7orf31, chromosome 7 open reading frame 31, [RH, Score=119, Expect=3e-27]} {Mouse: ENSMUSG00000029828, 4921507P07Rik, RIKEN cDNA 4921507P07 gene, [RH, Score=110, Expect=1e-24]} {RNA1509_11592} {RNA1310_4450} {RNA815_12248}
13. MligTC455_22760 1202 25.04 Mlig455_005448

Neo: -

Age: -

 ELOVL4 2.53 - - - 0.852 0.961 0.717 Mlig455_005448 {REF} {Length: 1604} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=208.1]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=284, Expect=2e-95]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=281, Expect=7e-95]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [Score=204, Expect=3e-65]} {Celegans: WBGene00001244, elo-6, Elongation of very long chain fatty acids protein 6, [Score=81.6, Expect=4e-18]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=286, Expect=2e-97]} {RNA1509_11261} {RNA1310_21427.2} {RNA815_6649.1}
14. MligTC455_09472 23 0.47 Mlig455_059329

Neo: -

Age: -

 NGB 2.497 - - 0.735 - 0.951 0.811 Mlig455_059329 {REF} {Length: 2110} {Pfam: Globin [PF00042.24, score=52.9]} {Human: ENSG00000165553, NGB, neuroglobin, [RH, Score=48.5, Expect=8e-07]} {Mouse: ENSMUSG00000021032, Ngb, neuroglobin, [RH, Score=50.4, Expect=1e-07]} {RNA1310_93460} {RNA815_18392}
15. MligTC455_36097 2740 57.08 Mlig455_040117, Mlig455_067335

Neo: -

Age: -

 ANKDD1A 1.883 - - - 0.921 0.962 -

Mlig455_040117 {REF} {Length: 2659} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=188.9]; Ankyrin repeats (many copies) [PF13637.8, score=157.3]; Ankyrin repeats (many copies) [PF13857.8, score=149.0]; Ankyrin repeat [PF13606.8, score=142.1]; Ankyrin repeat [PF00023.32, score=132.4]; Death domain [PF00531.24, score=24.1]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [Score=228, Expect=9e-67]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [Score=241, Expect=8e-72]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=138, Expect=1e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=135, Expect=9e-33]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=456, Expect=2e-154]} {RNA1509_19327} {RNA1310_8321.1, RNA1509_19327} {RNA1509_19327, RNA815_4521.1}

Mlig455_067335 {REF} {Length: 2660} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=188.4]; Ankyrin repeats (many copies) [PF13637.8, score=155.8]; Ankyrin repeats (many copies) [PF13857.8, score=148.9]; Ankyrin repeat [PF13606.8, score=140.8]; Ankyrin repeat [PF00023.32, score=132.9]; Death domain [PF00531.24, score=24.1]} {Human: ENSG00000166839, ANKDD1A, ankyrin repeat and death domain containing 1A, [Score=228, Expect=1e-66]} {Mouse: ENSMUSG00000066510, Ankdd1a, ankyrin repeat and death domain containing 1A, [Score=241, Expect=8e-72]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=137, Expect=2e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=135, Expect=8e-33]} {Smed: dd_Smed_v6_7532_0_1, dd_Smed_v6_7532_0_1, [RH, Score=456, Expect=2e-154]} {RNA1509_19327} {RNA1310_8321.1} {RNA815_4521.1}
16. MligTC455_40201 607 12.65 Mlig455_052028

Neo: -

Age: logFC(26M/2M)=-0.526

 DCLK3 1.878 - - - 0.906 0.972 - Mlig455_052028 {REF} {Length: 3990} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.8]; Fungal protein kinase [PF17667.3, score=26.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.0]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=370, Expect=2e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=8e-110]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=369, Expect=3e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=295, Expect=7e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=351, Expect=2e-105]} {RNA1509_13597} {RNA1310_2158.1} {RNA815_2598}
17. MligTC455_40202 595 12.39 Mlig455_057253

Neo: -

Age: logFC(26M/2M)=-0.440

 DCLK3 1.873 - - - 0.901 0.972 - Mlig455_057253 {REF} {Length: 4012} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.9]; Fungal protein kinase [PF17667.3, score=25.3]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.9]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=371, Expect=1e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=2e-113]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=370, Expect=1e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=296, Expect=6e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=352, Expect=1e-105]} {RNA1509_13597, RNA1509_49808} {RNA1310_2158.1, RNA1509_13597, RNA1509_49808} {RNA1509_13597, RNA1509_49808, RNA815_2598}
18. MligTC455_49596 1668 34.74 Mlig455_063375

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R2: 1.067/0.02988

 ARMC4 1.833 - - - 0.874 0.959 - Mlig455_063375 {REF} {Length: 3432} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=192.9]; HEAT repeats [PF13646.8, score=53.0]; Armadillo-like [PF04826.15, score=26.7]; V-ATPase subunit H [PF11698.10, score=26.4]; HEAT-like repeat [PF13513.8, score=26.1]; Kinesin-associated protein (KAP) [PF05804.14, score=24.7]; V-ATPase subunit H [PF03224.16, score=23.0]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=22.2]; HEAT repeat [PF02985.24, score=19.6]} {Human: ENSG00000169126, ARMC4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Mouse: ENSMUSG00000061802, Armc4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Dmel: FBgn0031905, gudu, [RH, Score=592, Expect=0.0]} {Smed: dd_Smed_v6_5065_0_1, dd_Smed_v6_5065_0_1, [RH, Score=932, Expect=0.0]} {RNA1509_1009, RNA1509_21601} {RNA1310_2954.1, RNA1509_1009, RNA1509_21601} {RNA1509_1009, RNA1509_21601, RNA815_1045}
19. MligTC455_18954 970 20.2 Mlig455_012818

Neo: -

Age: Down-Up-Up

 1.827 - - - 0.957 0.870 - Mlig455_012818 {REF} {Length: 1632} {Smed: dd_Smed_v6_5259_0_1, dd_Smed_v6_5259_0_1, [RH, Score=55.5, Expect=1e-09]} {RNA1509_36783, RNA1509_40417, RNA1509_59402} {RNA1310_20651.1, RNA1509_36783, RNA1509_40417, RNA1509_59402} {RNA1509_36783, RNA1509_40417, RNA1509_59402, RNA815_9212.1}
20. MligTC455_29772 225 4.68 Mlig455_061433, Mlig455_061441

Neo: -

Age: Down-Up-Up

 MAP3K19 1.805 - - 0.952 - 0.853 -

Mlig455_061433 {REF} {Length: 1580} {NoTransDecoderORF} {RNA1509_6748} {RNA1310_47210.1} {RNA815_24422.1}

Mlig455_061441 {REF} {Length: 2974} {Pfam: Protein kinase domain [PF00069.27, score=189.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=146.8]; Ankyrin repeats (many copies) [PF13637.8, score=76.8]; Ankyrin repeats (3 copies) [PF12796.9, score=64.8]; Ankyrin repeats (many copies) [PF13857.8, score=47.0]; Ankyrin repeat [PF13606.8, score=35.3]; Fungal protein kinase [PF17667.3, score=28.3]; Ankyrin repeat [PF00023.32, score=25.8]; ABC1 atypical kinase-like domain [PF03109.18, score=24.8]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=155, Expect=5e-39]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=151, Expect=4e-39]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=139, Expect=1e-34]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=127, Expect=1e-30]} {Smed: dd_Smed_v6_2030_0_11, dd_Smed_v6_2030_0_11, [Score=129, Expect=2e-32]} {RNA1509_45037} {RNA1310_19968} {RNA815_5323.1}
21. MligTC455_40052 513 10.68 Mlig455_035856

Neo: -

Age: -

 1.769 - - - 0.811 0.958 - Mlig455_035856 {REF} {Length: 3180} {TRANSSPLICED} {Smed: dd_Smed_v6_14291_0_1, dd_Smed_v6_14291_0_1, [RH, Score=221, Expect=3e-61]} {RNA1509_6964} {RNA1310_5805} {RNA815_1720}
22. MligTC455_08178 288 6.01 Mlig455_062827

Neo: -

Age: Down-Up-Down

 ANK2 1.706 - - - 0.955 0.751 - Mlig455_062827 {REF} {Length: 2430} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=60.2]; Ankyrin repeat [PF00023.32, score=47.3]; Ankyrin repeats (many copies) [PF13637.8, score=34.0]; Ankyrin repeats (many copies) [PF13857.8, score=33.9]; Ankyrin repeat [PF13606.8, score=31.7]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=50.8, Expect=3e-06]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=50.8, Expect=2e-06]; ENSMUSG00000047117, Ankdd1b, ankyrin repeat and death domain containing 1B, [Score=50.4, Expect=2e-06]} {Dmel: FBgn0039590, CG10011, [Score=48.1, Expect=1e-05]} {Smed: dd_Smed_v6_2072_0_26, dd_Smed_v6_2072_0_26, [Score=48.9, Expect=4e-06]} {RNA1509_10786} {RNA1310_15894} {RNA815_6009}
23. MligTC455_42227 1213 25.28 Mlig455_004225, Mlig455_031049

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.914/0.00168

 LRGUK 1.699 - - 0.976 - 0.723 -

Mlig455_004225 {REF} {Length: 3526} {Pfam: Guanylate kinase [PF00625.23, score=97.8]; Leucine rich repeat [PF13855.8, score=83.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=81.7]; Leucine-rich repeat [PF14580.8, score=68.6]; Leucine Rich repeat [PF13516.8, score=23.6]} {Human: ENSG00000155530, LRGUK, leucine rich repeats and guanylate kinase domain containing, [RH, Score=416, Expect=7e-131]} {Mouse: ENSMUSG00000056215, Lrguk, leucine-rich repeats and guanylate kinase domain containing, [RH, Score=429, Expect=3e-139]} {Dmel: FBgn0036099, CG11811, [Score=107, Expect=8e-26]} {Celegans: WBGene00011637, sds-22, Protein phosphatase 1 regulatory subunit SDS22 homolog, [Score=87.0, Expect=2e-18]} {Smed: dd_Smed_v6_9362_0_1, dd_Smed_v6_9362_0_1, [RH, Score=405, Expect=5e-131]} {RNA1509_3553} {RNA1310_6024.1, RNA1509_3553} {RNA1509_3553, RNA815_2429}

Mlig455_031049 {REF} {Length: 3115} {Pfam: Leucine rich repeat [PF13855.8, score=92.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=86.2]; Leucine-rich repeat [PF14580.8, score=60.1]; Leucine Rich repeat [PF13516.8, score=24.3]; Guanylate kinase [PF00625.23, score=23.6]; Leucine Rich Repeat [PF00560.35, score=21.3]} {Human: ENSG00000155530, LRGUK, leucine rich repeats and guanylate kinase domain containing, [Score=281, Expect=3e-85]} {Mouse: ENSMUSG00000056215, Lrguk, leucine-rich repeats and guanylate kinase domain containing, [Score=276, Expect=7e-84]} {Dmel: FBgn0028992, sds22, [Score=71.2, Expect=3e-13]} {Celegans: WBGene00011637, sds-22, Protein phosphatase 1 regulatory subunit SDS22 homolog, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_9362_0_1, dd_Smed_v6_9362_0_1, [Score=259, Expect=2e-78]} {RNA1509_3553} {RNA1310_6024.2} {RNA815_2429}
24. MligTC455_17296 134 2.79 Mlig455_037848

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.847

 PIGW 1.674 - - - 0.703 0.971 - Mlig455_037848 {REF} {Length: 2875} {Pfam: GWT1 [PF06423.14, score=77.4]} {Human: ENSG00000277161, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=92.4, Expect=4e-19]; ENSG00000275600, PIGW, phosphatidylinositol glycan anchor biosynthesis class W, [Score=92.4, Expect=4e-19]} {Mouse: ENSMUSG00000045140, Pigw, phosphatidylinositol glycan anchor biosynthesis, class W, [Score=107, Expect=4e-24]} {Dmel: FBgn0031422, PIG-Wa, Phosphatidylinositol glycan anchor biosynthesis class W a, [Score=117, Expect=4e-28]} {Celegans: WBGene00022447, hpo-20, Phosphatidylinositol-glycan biosynthesis class W protein, [Score=97.1, Expect=4e-21]} {Smed: dd_Smed_v6_14190_0_1, dd_Smed_v6_14190_0_1, [Score=96.3, Expect=3e-21]} {RNA1509_28166} {RNA1310_42427} {RNA815_4044}
25. MligTC455_27439 211 4.4 Mlig455_040407

Neo: -

Age: -

 1.673 - - 0.963 - - 0.710 Mlig455_040407 {REF} {Length: 590} {RNA1310_75750} {RNA815_36038.1}
26. MligTC455_50109 681 14.18 Mlig455_035951

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.431

 COP1 1.672 - - - 0.953 - 0.719 Mlig455_035951 {REF} {Length: 2678} {Pfam: Ring finger domain [PF13639.8, score=20.7]} {Human: ENSG00000143207, COP1, COP1, E3 ubiquitin ligase, [RH, Score=47.8, Expect=2e-06]} {Smed: dd_Smed_v6_2170_0_1, dd_Smed_v6_2170_0_1, [Score=164, Expect=7e-45]} {RNA1509_12012} {RNA1310_3106, RNA1509_12012} {RNA1509_12012, RNA815_15680}
27. MligTC455_18684 442 9.2 Mlig455_048930, Mlig455_048954

Neo: -

Age: Down-Up-Up

 MAP3K3 0.974 - - - - 0.974 -

Mlig455_048930 {REF} {Length: 1361} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=182.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=127.3]; ABC1 atypical kinase-like domain [PF03109.18, score=21.7]; PB1 domain [PF00564.26, score=19.1]} {Human: ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=229, Expect=2e-68]} {Mouse: ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=228, Expect=3e-68]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=155, Expect=2e-41]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=154, Expect=5e-41]} {Smed: dd_Smed_v6_9266_0_1, dd_Smed_v6_9266_0_1, [Score=196, Expect=4e-57]} {RNA1509_27897} {RNA1310_25374} {RNA815_11066}

Mlig455_048954 {REF} {Length: 1360} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=37.5]; PB1 domain [PF00564.26, score=20.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=18.3]} {Human: ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=81.3, Expect=4e-17]; ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [Score=79.0, Expect=2e-16]} {Mouse: ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=81.3, Expect=3e-17]; ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [Score=78.2, Expect=2e-16]} {RNA1509_27897} {RNA1310_25374} {RNA815_11066}
28. MligTC455_10217 100 2.08 Mlig455_042730

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.306/0.02912
Region-enriched R3: 3.318/0.03227

 0.968 - - - - 0.968 - Mlig455_042730 {REF} {Length: 1398} {RNA1509_44180} {RNA1310_20217} {RNA815_8842}
29. MligTC455_27837 39 0.81 Mlig455_007266

Neo: -

Age: Down-Up-Down

 0.963 - - - - 0.963 - Mlig455_007266 {REF} {Length: 5168} {Pfam: Integrase zinc binding domain [PF17921.3, score=71.6]; Integrase core domain [PF00665.28, score=50.6]; DDE superfamily endonuclease [PF13358.8, score=21.8]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=208, Expect=2e-61]} {RNA1509_20493} {RNA1310_131.1} {RNA815_52.1}
30. MligTC455_49240 969 20.18 Mlig455_064870

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.538

 CERK 0.963 - - - 0.963 - - Mlig455_064870 {REF} {Length: 2740} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=78.7]; Ceramide kinase C-terminal domain [PF19280.1, score=61.3]; YegS C-terminal NAD kinase beta sandwich-like domain [PF19279.1, score=23.2]} {Human: ENSG00000100422, CERK, ceramide kinase, [RH, Score=230, Expect=2e-68]} {Mouse: ENSMUSG00000035891, Cerk, ceramide kinase, [RH, Score=229, Expect=3e-68]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [RH, Score=181, Expect=2e-49]} {Celegans: WBGene00020398, cerk-1, Ceramide kinase 1, [Score=143, Expect=1e-36]} {Smed: dd_Smed_v6_9323_0_1, dd_Smed_v6_9323_0_1, [RH, Score=273, Expect=1e-85]} {RNA1509_7173} {RNA1310_7457.1, RNA1509_7173} {RNA1509_7173, RNA815_12572}
31. MligTC455_40756 35 0.73 Mlig455_050356, Mlig455_065112

Neo: -

Age: -

 0.961 - - - - 0.961 -

Mlig455_050356 {REF} {Length: 740} {NoTransDecoderORF} {RNA1509_38191} {RNA1310_5321.1} {RNA815_14836}

Mlig455_065112 {REF} {Length: 277} {NoTransDecoderORF} {RNA1509_38191} {RNA1310_5321.1} {RNA815_14836}
32. MligTC455_46835 286 5.95 Mlig455_044319

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.222

 0.961 - - - - - 0.961 Mlig455_044319 {REF} {Length: 3046} {Pfam: Bacterial TSP3 repeat [PF18884.2, score=18.6]} {RNA1509_127} {RNA1310_66832} {RNA815_4383.4}
33. MligTC455_53612 1108 23.09 Mlig455_023847, Mlig455_046530, Mlig455_046638, Mlig455_046657

Neo: -

Age: Down-Up-Up

Region-enriched R2: 1.470/0.03843

 0.961 - - - 0.961 - -

Mlig455_023847 {REF} {Length: 2954} {TRANSSPLICED} {RNA1509_48720, RNA1509_59611} {RNA1310_8026, RNA1509_48720, RNA1509_59611} {RNA1509_48720, RNA1509_59611, RNA815_3300.1}

Mlig455_046530 {REF} {Length: 2423} {RNA1509_56940} {RNA1310_8026} {RNA815_3300.1}

Mlig455_046638 {REF} {Length: 2807} {RNA1509_56940} {RNA1310_8026} {RNA815_3300.1}

Mlig455_046657 {REF} {Length: 2718} {RNA1509_56940} {RNA1310_8026, RNA1509_56940} {RNA1509_56940, RNA815_3300.1}
34. MligTC455_06965 768 15.99 Mlig455_011672, Mlig455_011674, Mlig455_049919

Neo: -

Age: Down-Up-Up

 NOTCH1 0.956 - - 0.956 - - -

Mlig455_011672 {REF} {Length: 815} {RNA1509_54595} {RNA1310_59282} {RNA815_18996}

Mlig455_011674 {REF} {Length: 490} {NoTransDecoderORF} {RNA1509_54595} {RNA1310_59282} {RNA815_18996}

Mlig455_049919 {REF} {Length: 1587} {Pfam: EGF-like domain [PF00008.29, score=27.3]; EGF-like domain [PF07974.15, score=23.4]; Human growth factor-like EGF [PF12661.9, score=19.7]} {Human: ENSG00000148400, NOTCH1, notch 1, [Score=53.9, Expect=2e-08]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [Score=52.0, Expect=7e-08]; ENSMUSG00000026923, Notch1, notch 1, [Score=51.6, Expect=9e-08]} {Dmel: FBgn0259140, CG42255, [Score=50.4, Expect=2e-07]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=52.4, Expect=2e-08]} {RNA1509_54595} {RNA1310_59282} {RNA815_18996}
35. MligTC455_16225 212 4.42 Mlig455_019360

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.571

 0.956 - - - - 0.956 - Mlig455_019360 {REF} {Length: 2345} {Smed: dd_Smed_v6_16150_0_1, dd_Smed_v6_16150_0_1, [RH, Score=93.2, Expect=5e-20]} {RNA1509_34395} {RNA1310_13154, RNA1509_34395} {RNA1509_34395, RNA815_10500}
36. MligTC455_31649 44 0.93 Mlig455_007325, Mlig455_008077, Mlig455_036688, Mlig455_044932, Mlig455_069853

Neo: -

Age: Up-Down-Down

 TRPM3 0.952 - - - - 0.952 -

Mlig455_007325 {REF} {Length: 4316} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=127.7]; Endonuclease-reverse transcriptase [PF14529.8, score=75.9]} {RNA1509_32599} {RNA1310_1582} {RNA815_252.1}

Mlig455_008077 {REF} {Length: 1249} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=137.9]; Ankyrin repeats (many copies) [PF13637.8, score=96.4]; Ankyrin repeat [PF13606.8, score=60.8]; Ankyrin repeats (many copies) [PF13857.8, score=57.2]; Ankyrin repeat [PF00023.32, score=37.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=101, Expect=1e-20]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=103, Expect=2e-21]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=85.9, Expect=3e-16]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.1, Expect=1e-11]} {Smed: dd_Smed_v6_10717_0_1, dd_Smed_v6_10717_0_1, [Score=100, Expect=6e-21]} {RNA1509_45496} {RNA1310_1582} {RNA815_252.3}

Mlig455_036688 {REF} {Length: 698} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=137.9]; Ankyrin repeats (many copies) [PF13637.8, score=96.4]; Ankyrin repeat [PF13606.8, score=60.8]; Ankyrin repeats (many copies) [PF13857.8, score=57.2]; Ankyrin repeat [PF00023.32, score=37.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=101, Expect=1e-20]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=103, Expect=2e-21]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=85.9, Expect=3e-16]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=70.1, Expect=1e-11]} {Smed: dd_Smed_v6_10717_0_1, dd_Smed_v6_10717_0_1, [Score=100, Expect=6e-21]} {RNA1509_45496} {RNA1310_1582} {RNA815_252.1}

Mlig455_044932 {REF} {Length: 842} {TRANSSPLICED} {Pfam: Endonuclease-reverse transcriptase [PF14529.8, score=77.0]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=18.8]} {RNA1509_45496} {RNA1310_1659} {RNA815_252.3}

Mlig455_069853 {REF} {Length: 5003} {TRANSSPLICED} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=117.8]; Endonuclease-reverse transcriptase [PF14529.8, score=73.1]} {RNA1509_45496} {RNA1310_1582} {RNA815_252.1}
37. MligTC455_39518 40 0.83 Mlig455_031401

Neo: -

Age: -

 CHRNA1 0.95 - - - - 0.950 - Mlig455_031401 {REF} {Length: 2411} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=92.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=76.4]} {Human: ENSG00000138435, CHRNA1, cholinergic receptor nicotinic alpha 1 subunit, [Score=120, Expect=3e-29]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=120, Expect=2e-29]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=115, Expect=2e-27]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=114, Expect=3e-27]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=134, Expect=2e-34]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=135, Expect=1e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=124, Expect=5e-31]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=114, Expect=2e-27]} {RNA1509_53098} {RNA1310_67430} {RNA815_23438}
38. MligTC455_39794 787 16.39 Mlig455_051184

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.481

 0.95 - - - 0.950 - - Mlig455_051184 {REF} {Length: 1501} {TRANSSPLICED} {Smed: dd_Smed_v6_2398_0_1, dd_Smed_v6_2398_0_1, [RH, Score=167, Expect=1e-50]} {RNA1509_25151} {RNA1310_14303.1} {RNA815_5283}

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