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Results for MligTC455_10931

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_10931 58 1.21 Mlig455_010937

Neo: -

Age: -

Region-enriched R8: 5.091/0.01315

 Mlig455_010937 {REF} {Length: 2035} {Pfam: Galactose binding lectin domain [PF02140.20, score=44.7]} {RNA1310_25216} {RNA815_30839}

Cumulative graph for MligTC455_10931

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.444 1.182 0.99952 1.00000
RegionR2 0.436 1.182 0.48481 0.86791
RegionR3 -2.858 1.182 0.99966 1.00000
RegionR4 0.09 1.182 0.59523 0.90914
RegionR5 0.525 1.182 0.31870 0.65973
RegionR6 -3.36 1.182 0.99964 1.00000
RegionR7 1.52 1.182 0.23621 0.86042
RegionR8 5.091 1.182 0.00018 0.01315

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.946 1.182 0.99996 1.00000
RegenerationR2 -0.377 1.182 0.64783 0.93520
RegenerationR3 2.007 1.182 0.19941 0.63409
RegenerationR4 -0.506 1.182 0.87175 1.00000
RegenerationR5 -0.706 1.182 0.50090 0.85895
RegenerationR6 3.233 1.182 0.08741 0.36967
RegenerationBL -0.441 1.182 0.76538 1.00000
RegenerationTP -0.857 1.182 0.43520 0.85630


Genes with expression patterns similar to MligTC455_10931

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_10931 58 1.21 Mlig455_010937

Neo: -

Age: -

Region-enriched R8: 5.091/0.01315

 4 - - 1.000 1.000 1.000 1.000 Mlig455_010937 {REF} {Length: 2035} {Pfam: Galactose binding lectin domain [PF02140.20, score=44.7]} {RNA1310_25216} {RNA815_30839}
2. MligTC455_39312 101 2.11 Mlig455_002158

Neo: -

Age: -

 CFAP99 1.888 - - - - 0.930 0.958 Mlig455_002158 {REF} {Length: 4740} {Pfam: Thyroglobulin type-1 repeat [PF00086.20, score=82.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=43.8]; Kazal-type serine protease inhibitor domain [PF07648.17, score=35.9]; Kazal-type serine protease inhibitor domain [PF00050.23, score=35.3]; EF-hand domain pair [PF13499.8, score=29.0]; EF-hand domain [PF13405.8, score=27.5]; EF hand [PF00036.34, score=23.2]; EF hand [PF13202.8, score=19.1]} {Human: ENSG00000206113, CFAP99, cilia and flagella associated protein 99, [RH, Score=302, Expect=4e-88]} {Mouse: ENSMUSG00000109572, Cfap99, cilia and flagella associated protein 99, [RH, Score=308, Expect=3e-90]} {Dmel: FBgn0262169, magu, [RH, Score=144, Expect=4e-35]} {Smed: dd_Smed_v6_8538_0_1, dd_Smed_v6_8538_0_1, [RH, Score=342, Expect=5e-103]} {RNA1509_16659} {RNA1310_6756} {RNA815_2531}
3. MligTC455_43755 1306 27.21 Mlig455_010280

Neo: -

Age: -

Region-enriched R7: 1.117/0.04060

Regeneration-downregulated BL: -2.741

Regeneration-depleted BL: -2.741

 SMTN 1.873 - - - 0.919 - 0.954 Mlig455_010280 {REF} {Length: 2087} {Pfam: Calponin homology (CH) domain [PF00307.33, score=83.4]; Smoothelin cytoskeleton protein [PF12510.10, score=35.2]; CAMSAP CH domain [PF11971.10, score=32.4]} {Human: ENSG00000183963, SMTN, smoothelin, [RH, Score=168, Expect=2e-45]} {Mouse: ENSMUSG00000020439, Smtn, smoothelin, [RH, Score=162, Expect=2e-43]} {Dmel: FBgn0085446, CG34417, [RH, Score=160, Expect=7e-43]} {Celegans: WBGene00020530, T15B12.1, [RH, Score=144, Expect=4e-39]} {Smed: dd_Smed_v6_2554_0_1, dd_Smed_v6_2554_0_1, [RH, Score=176, Expect=2e-54]} {RNA1509_21748} {RNA1310_16112} {RNA815_14550}
4. MligTC455_53278 158 3.28 Mlig455_006949

Neo: -

Age: -

Regeneration-enriched TP: 10.826
Regeneration-enriched BL: 9.300
Regeneration-enriched R3: 8.515
Regeneration-enriched R6: 7.811
Regeneration-enriched R4: 7.808
Regeneration-enriched R5: 7.623

 1.872 - - - 0.954 - 0.918 Mlig455_006949 {REF} {Length: 1237} {RNA1509_34269} {RNA1310_44808} {RNA815_8213}
5. MligTC455_26054 49 1.02 Mlig455_024874

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.844

 MPEG1 1.853 - - - 0.892 - 0.961 Mlig455_024874 {REF} {Length: 3027} {Pfam: MAC/Perforin domain [PF01823.21, score=80.3]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [Score=357, Expect=3e-112]} {Mouse: ENSMUSG00000040065, Pfpl, pore forming protein-like, [RH, Score=340, Expect=4e-106]} {Smed: dd_Smed_v6_10990_0_1, dd_Smed_v6_10990_0_1, [RH, Score=335, Expect=2e-104]} {RNA1509_45077} {RNA1310_5939} {RNA815_2438}
6. MligTC455_15489 64 1.34 Mlig455_007936, Mlig455_008038

Neo: -

Age: -

Region-enriched R2: 5.213/0.00031

 DIRAS2 1.831 - - 0.972 - 0.859 -

Mlig455_007936 {REF} {Length: 1262} {Pfam: Ras family [PF00071.24, score=149.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=66.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.2]; RsgA GTPase [PF03193.18, score=27.4]; ADP-ribosylation factor family [PF00025.23, score=24.3]; Ferrous iron transport protein B [PF02421.20, score=19.3]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.0]} {Human: ENSG00000165023, DIRAS2, DIRAS family GTPase 2, [RH, Score=263, Expect=1e-88]} {Mouse: ENSMUSG00000047842, Diras2, DIRAS family, GTP-binding RAS-like 2, [RH, Score=262, Expect=2e-88]} {Dmel: FBgn0037754, CG8500, [RH, Score=237, Expect=3e-78]} {Celegans: WBGene00016911, drn-1, GTP-binding protein drn-1, [RH, Score=236, Expect=4e-78]} {Smed: dd_Smed_v6_10778_0_1, dd_Smed_v6_10778_0_1, [RH, Score=245, Expect=3e-82]} {RNA1509_35041} {RNA1310_23187} {RNA815_16187}

Mlig455_008038 {REF} {Length: 1497} {Pfam: Ras family [PF00071.24, score=149.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=66.1]; 50S ribosome-binding GTPase [PF01926.25, score=28.1]; RsgA GTPase [PF03193.18, score=27.5]; ADP-ribosylation factor family [PF00025.23, score=24.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.1]; Ferrous iron transport protein B [PF02421.20, score=19.1]} {Human: ENSG00000165023, DIRAS2, DIRAS family GTPase 2, [RH, Score=263, Expect=1e-88]} {Mouse: ENSMUSG00000047842, Diras2, DIRAS family, GTP-binding RAS-like 2, [RH, Score=262, Expect=3e-88]} {Dmel: FBgn0037754, CG8500, [RH, Score=237, Expect=4e-78]} {Celegans: WBGene00016911, drn-1, GTP-binding protein drn-1, [RH, Score=236, Expect=5e-78]} {Smed: dd_Smed_v6_10778_0_1, dd_Smed_v6_10778_0_1, [RH, Score=246, Expect=4e-82]} {RNA1509_35041} {RNA1310_23187, RNA1509_35041} {RNA1509_35041, RNA815_16187}
7. MligTC455_37342 203 4.23 Mlig455_024018

Neo: -

Age: -

 1.77 - - - - 0.953 0.817 Mlig455_024018 {REF} {Length: 1374} {RNA1509_59718} {RNA1310_33285} {RNA815_22262}
8. MligTC455_36981 59 1.23 Mlig455_050314

Neo: -

Age: -

Region-enriched R2: 4.760/0.03524

 ASIC5 1.767 - - 0.950 - 0.817 - Mlig455_050314 {REF} {Length: 3328} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=158.3]; Kringle domain [PF00051.20, score=20.5]} {Human: ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=59.3, Expect=2e-08]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=51.6, Expect=3e-06]} {Smed: dd_Smed_v6_16557_0_1, dd_Smed_v6_16557_0_1, [Score=52.8, Expect=6e-07]} {RNA1310_9846.1} {RNA815_21595}
9. MligTC455_52351 280 5.84 Mlig455_037161, Mlig455_038476, Mlig455_052313

Neo: -

Age: Down-Up-Up

Region-enriched R8: 4.109/0.00021
Region-enriched R7: 3.048/0.01067

 CALM2 1.761 - - 0.795 - - 0.966

Mlig455_037161 {REF} {Length: 1076} {Pfam: EF-hand domain pair [PF13499.8, score=39.3]; EF hand [PF00036.34, score=24.4]; EF-hand domain [PF13405.8, score=24.1]; EF-hand domain pair [PF13833.8, score=21.3]; EF-hand domain [PF14658.8, score=21.2]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=2e-22]; ENSG00000160014, CALM3, calmodulin 3, [Score=92.4, Expect=2e-22]; ENSG00000198668, CALM1, calmodulin 1, [Score=92.4, Expect=1e-22]; ENSG00000178363, CALML3, calmodulin like 3, [Score=90.1, Expect=1e-21]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=93.2, Expect=2e-22]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=92.4, Expect=1e-22]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=92.4, Expect=1e-22]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=92.4, Expect=1e-22]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=92.0, Expect=1e-22]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=92.0, Expect=9e-23]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=92.0, Expect=7e-23]} {RNA1310_8603.1} {RNA815_31151.1}

Mlig455_038476 {REF} {Length: 855} {Pfam: EF-hand domain pair [PF13499.8, score=40.9]; EF hand [PF00036.34, score=26.1]; EF-hand domain [PF13405.8, score=25.6]; EF-hand domain pair [PF13833.8, score=22.7]; EF-hand domain [PF14658.8, score=22.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=92.4, Expect=8e-23]; ENSG00000160014, CALM3, calmodulin 3, [Score=92.0, Expect=5e-23]; ENSG00000198668, CALM1, calmodulin 1, [Score=92.0, Expect=5e-23]; ENSG00000178363, CALML3, calmodulin like 3, [Score=89.0, Expect=7e-22]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=92.4, Expect=8e-23]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=92.0, Expect=4e-23]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=92.0, Expect=4e-23]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=91.3, Expect=6e-23]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=91.3, Expect=5e-23]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=90.9, Expect=4e-23]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=90.9, Expect=3e-23]} {RNA1310_8603.1} {RNA815_31151.1}

Mlig455_052313 {REF} {Length: 1073} {Pfam: EF-hand domain pair [PF13499.8, score=33.5]; EF hand [PF00036.34, score=23.1]; EF-hand domain pair [PF13833.8, score=21.8]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=80.9, Expect=5e-18]; ENSG00000198668, CALM1, calmodulin 1, [Score=80.5, Expect=3e-18]; ENSG00000160014, CALM3, calmodulin 3, [Score=80.1, Expect=3e-18]; ENSG00000178363, CALML3, calmodulin like 3, [Score=79.3, Expect=7e-18]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=81.3, Expect=9e-19]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=80.9, Expect=3e-18]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=80.1, Expect=2e-18]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=80.1, Expect=2e-18]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=79.7, Expect=3e-18]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=79.7, Expect=2e-18]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=79.7, Expect=2e-18]} {RNA1310_8603.1} {RNA815_31151.1}
10. MligTC455_20404 2355 49.05 Mlig455_053980

Neo: -

Age: -

Region-enriched R7: 4.495/0.00000
Region-enriched R8: 4.318/0.00000

Regeneration-downregulated BL: -4.662

Regeneration-depleted BL: -4.662

 1.759 - - - 0.804 - 0.955 Mlig455_053980 {REF} {Length: 505} {NoTransDecoderORF} {RNA1509_5548} {RNA1310_94516} {RNA815_53532}
11. MligTC455_35505 126 2.62 Mlig455_018997, Mlig455_022533, Mlig455_055707

Neo: -

Age: -

 HRH2, SYT7 1.757 - - 0.963 - 0.794 -

Mlig455_018997 {REF} {Length: 4854} {Pfam: C2 domain [PF00168.32, score=156.5]} {Human: ENSG00000011347, SYT7, synaptotagmin 7, [RH, Score=271, Expect=9e-84]} {Mouse: ENSMUSG00000024743, Syt7, synaptotagmin VII, [RH, Score=261, Expect=3e-81]} {Dmel: FBgn0039900, Syt7, Synaptotagmin 7, [RH, Score=243, Expect=4e-76]} {Celegans: WBGene00004926, snt-6, SyNapTotagmin, [RH, Score=182, Expect=1e-53]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=199, Expect=6e-60]} {RNA1310_29722} {RNA815_16467}

Mlig455_022533 {REF} {Length: 1223} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=80.1]} {Human: ENSG00000113749, HRH2, histamine receptor H2, [Score=68.6, Expect=4e-12]} {Mouse: ENSMUSG00000044338, Aplnr, apelin receptor, [Score=64.3, Expect=7e-11]; ENSMUSG00000037424, Taar9, trace amine-associated receptor 9, [Score=63.9, Expect=9e-11]; ENSMUSG00000034987, Hrh2, histamine receptor H2, [Score=63.2, Expect=2e-10]} {Dmel: FBgn0039595, AstA-R2, Allatostatin A receptor 2, [Score=53.1, Expect=2e-07]} {Smed: dd_Smed_v6_15036_0_1, dd_Smed_v6_15036_0_1, [Score=63.2, Expect=9e-11]}

Mlig455_055707 {REF} {Length: 2803} {Pfam: C2 domain [PF00168.32, score=156.6]} {Human: ENSG00000011347, SYT7, synaptotagmin 7, [RH, Score=270, Expect=2e-83]} {Mouse: ENSMUSG00000024743, Syt7, synaptotagmin VII, [RH, Score=259, Expect=4e-81]} {Dmel: FBgn0039900, Syt7, Synaptotagmin 7, [RH, Score=243, Expect=2e-76]} {Celegans: WBGene00004926, snt-6, SyNapTotagmin, [RH, Score=182, Expect=1e-53]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=199, Expect=4e-60]} {RNA1310_29722} {RNA815_16467}
12. MligTC455_11888 142 2.96 Mlig455_065110

Neo: -

Age: -

 PCDH11X 1.746 - - 0.758 - 0.988 - Mlig455_065110 {REF} {Length: 4103} {Pfam: Cadherin domain [PF00028.19, score=207.8]; Cadherin-like [PF16184.7, score=34.7]; Cadherin-like [PF08266.14, score=23.4]} {Human: ENSG00000102290, PCDH11X, protocadherin 11 X-linked, [Score=273, Expect=3e-74]; ENSG00000099715, PCDH11Y, protocadherin 11 Y-linked, [Score=271, Expect=1e-73]} {Mouse: ENSMUSG00000034755, Pcdh11x, protocadherin 11 X-linked, [Score=278, Expect=6e-76]} {Dmel: FBgn0261574, kug, kugelei, [Score=177, Expect=4e-44]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=144, Expect=2e-34]} {Smed: dd_Smed_v6_12023_0_1, dd_Smed_v6_12023_0_1, [Score=322, Expect=1e-92]} {RNA1509_38191} {RNA1310_74429} {RNA815_12734}
13. MligTC455_16451 61 1.26 Mlig455_037847

Neo: -

Age: -

 1.71 - - 0.957 - 0.753 - Mlig455_037847 {REF} {Length: 931}
14. MligTC455_40245 125 2.61 Mlig455_045020

Neo: -

Age: -

Region-enriched R8: 2.724/0.00842

 1.697 - - - 0.969 - 0.728 Mlig455_045020 {REF} {Length: 4797} {RNA1509_7608} {RNA1310_23716} {RNA815_45025.1}
15. MligTC455_44725 67 1.4 Mlig455_024194

Neo: -

Age: -

 1.691 - - - - 0.719 0.972 Mlig455_024194 {REF} {Length: 956} {RNA1310_84543} {RNA815_47586}
16. MligTC455_10003 110 2.29 Mlig455_009380

Neo: -

Age: -

 1.688 - - - - 0.715 0.973 Mlig455_009380 {REF} {Length: 2126} {RNA1509_38062} {RNA1310_66742.1} {RNA815_8442.1}
17. MligTC455_37343 240 4.99 Mlig455_024086

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.659/0.04266

 1.681 - - - - 0.952 0.729 Mlig455_024086 {REF} {Length: 4209} {RNA1509_36528, RNA1509_59718} {RNA1310_12514, RNA1509_36528, RNA1509_59718} {RNA1509_36528, RNA1509_59718, RNA815_21020}
18. MligTC455_53839 106 2.21 Mlig455_008195, Mlig455_069578

Neo: -

Age: -

 1.681 - - 0.950 - 0.731 -

Mlig455_008195 {REF} {Length: 2376} {Smed: dd_Smed_v6_4245_0_1, dd_Smed_v6_4245_0_1, [Score=54.7, Expect=8e-08]} {RNA1310_37888} {RNA815_29107}

Mlig455_069578 {REF} {Length: 2376} {Smed: dd_Smed_v6_4245_0_1, dd_Smed_v6_4245_0_1, [Score=54.7, Expect=8e-08]} {RNA1310_37888} {RNA815_29107}
19. MligTC455_19450 194 4.05 Mlig455_065775, Mlig455_065798

Neo: -

Age: -

 1.657 - - 0.954 - 0.703 -

Mlig455_065775 {REF} {Length: 1864} {Pfam: Innexin [PF00876.20, score=26.9]} {RNA1509_47060} {RNA1310_19756.1} {RNA815_16217}

Mlig455_065798 {REF} {Length: 1809} {Pfam: Innexin [PF00876.20, score=26.9]} {RNA1509_47060} {RNA1310_19756.1} {RNA815_16217}
20. MligTC455_33474 29 0.61 Mlig455_066685

Neo: -

Age: -

 0.986 - - 0.986 - - - Mlig455_066685 {REF} {Length: 538} {NoTransDecoderORF} {RNA1509_34535} {RNA1310_86294.1} {RNA815_36906}
21. MligTC455_12391 21 0.43 Mlig455_059389

Neo: -

Age: -

 SSTR5 0.984 - - 0.984 - - - Mlig455_059389 {REF} {Length: 2086} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=121.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=28.0]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=26.9]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=24.9]} {Human: ENSG00000162009, SSTR5, somatostatin receptor 5, [Score=91.3, Expect=2e-19]; ENSG00000264717, NPY4R2, neuropeptide Y receptor Y4-2, [Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000045052, Prlhr, prolactin releasing hormone receptor, [Score=103, Expect=8e-24]; ENSMUSG00000048337, Npy4r, neuropeptide Y receptor Y4, [Score=102, Expect=2e-23]; ENSMUSG00000038071, Npy6r, neuropeptide Y receptor Y6, [Score=102, Expect=3e-23]} {Dmel: FBgn0037408, NPFR, Neuropeptide F receptor, [Score=114, Expect=8e-27]} {Celegans: WBGene00003808, npr-2, NeuroPeptide Receptor family, [Score=100, Expect=7e-23]} {Smed: dd_Smed_v6_26109_0_1, dd_Smed_v6_26109_0_1, [Score=191, Expect=5e-54]} {RNA1509_59439} {RNA1310_49826} {RNA815_38569}
22. MligTC455_43502 87 1.81 Mlig455_049275, Mlig455_050621

Neo: -

Age: Down-Down-Up

Region-enriched R8: 4.055/0.04204

 GPR139 0.983 - - 0.983 - - -

Mlig455_049275 {REF} {Length: 1973} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=70.2]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=40.7]} {Human: ENSG00000180269, GPR139, G protein-coupled receptor 139, [Score=51.2, Expect=2e-06]} {Mouse: ENSMUSG00000066197, Gpr139, G protein-coupled receptor 139, [Score=49.7, Expect=3e-06]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00016265, trhr-1, Thyrotropin-Releasing Hormone Receptor, [Score=64.3, Expect=4e-11]} {Smed: dd_Smed_v6_9550_0_1, dd_Smed_v6_9550_0_1, [Score=167, Expect=2e-47]} {RNA1509_46026} {RNA1310_15406} {RNA815_32015}

Mlig455_050621 {REF} {Length: 2103} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=70.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=39.9]} {Human: ENSG00000180269, GPR139, G protein-coupled receptor 139, [Score=49.3, Expect=6e-06]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=72.8, Expect=1e-13]} {Celegans: WBGene00016265, trhr-1, Thyrotropin-Releasing Hormone Receptor, [Score=60.8, Expect=5e-10]} {Smed: dd_Smed_v6_9550_0_1, dd_Smed_v6_9550_0_1, [RH, Score=168, Expect=7e-48]} {RNA1509_7660} {RNA1310_15406} {RNA815_32015}
23. MligTC455_50328 128 2.66 Mlig455_039843

Neo: -

Age: -

 SCNN1B 0.98 - - 0.980 - - - Mlig455_039843 {REF} {Length: 2793} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=206.6]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=69.3, Expect=1e-11]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=58.9, Expect=1e-08]; ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=57.4, Expect=4e-08]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=75.5, Expect=8e-14]} {Smed: dd_Smed_v6_23028_0_1, dd_Smed_v6_23028_0_1, [RH, Score=366, Expect=3e-118]} {RNA1509_37054} {RNA1310_10450, RNA1509_37054} {RNA1509_37054, RNA815_17111}
24. MligTC455_17788 34 0.71 Mlig455_042993

Neo: -

Age: -

 0.978 - - - - - 0.978 Mlig455_042993 {REF} {Length: 1462} {TRANSSPLICED} {RNA1310_18933} {RNA815_24996}
25. MligTC455_13333 116 2.42 Mlig455_017077

Neo: -

Age: -

 0.977 - - 0.977 - - - Mlig455_017077 {REF} {Length: 2070} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=19.5]} {RNA1509_11472} {RNA1310_17969} {RNA815_7860}
26. MligTC455_20819 30 0.63 Mlig455_010137

Neo: -

Age: -

 0.977 - - 0.977 - - - Mlig455_010137 {REF} {Length: 187} {NoTransDecoderORF} {RNA1509_44447} {RNA1310_132544} {RNA815_57653}
27. MligTC455_44724 186 3.88 Mlig455_024176

Neo: -

Age: -

Region-enriched R7: 3.890/0.00870

 0.976 - - - - - 0.976 Mlig455_024176 {REF} {Length: 967} {RNA1310_84543} {RNA815_47586}
28. MligTC455_12281 83 1.74 Mlig455_014532

Neo: -

Age: -

 0.974 - - 0.974 - - - Mlig455_014532 {REF} {Length: 718} {Pfam: DDE superfamily endonuclease [PF13359.8, score=26.4]} {RNA1509_49619} {RNA1310_9836} {RNA815_36431}
29. MligTC455_04897 17 0.36 Mlig455_049759

Neo: -

Age: -

 0.972 - - - - 0.972 - Mlig455_049759 {REF} {Length: 407} {NoTransDecoderORF}
30. MligTC455_39231 20 0.41 Mlig455_067555

Neo: -

Age: -

 0.971 - - - - - 0.971 Mlig455_067555 {REF} {Length: 2125} {Celegans: WBGene00016348, C33E10.6, [Score=111, Expect=2e-28]} {Smed: dd_Smed_v6_3268_0_3, dd_Smed_v6_3268_0_3, [Score=103, Expect=4e-28]} {RNA1509_47487} {RNA1310_8325.1} {RNA815_24633}
31. MligTC455_39723 249 5.18 Mlig455_022693, Mlig455_022705

Neo: -

Age: -

Region-enriched R2: 3.177/0.00982

 0.971 - - 0.971 - - -

Mlig455_022693 {REF} {Length: 1190} {TRANSSPLICED} {RNA1310_27415} {RNA815_16060}

Mlig455_022705 {REF} {Length: 1526} {TRANSSPLICED} {RNA1310_27415} {RNA815_16060}
32. MligTC455_28745 165 3.43 Mlig455_011834

Neo: -

Age: Up-Down-Up

 ITPR1 0.97 - - 0.970 - - - Mlig455_011834 {REF} {Length: 9842} {Pfam: RIH domain [PF01365.23, score=97.3]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=68.7]; RyR and IP3R Homology associated [PF08454.13, score=66.6]; MIR domain [PF02815.21, score=57.6]; Ion transport protein [PF00520.33, score=21.7]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=226, Expect=3e-58]; ENSG00000096433, ITPR3, inositol 1,4,5-trisphosphate receptor type 3, [Score=225, Expect=6e-58]; ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=220, Expect=2e-56]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=229, Expect=3e-59]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=154, Expect=9e-37]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=142, Expect=2e-33]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [RH, Score=3006, Expect=0.0]} {RNA1509_2749, RNA1509_40391} {RNA1310_434.2, RNA1509_40391} {RNA1509_40391, RNA815_1122}
33. MligTC455_34446 25 0.51 Mlig455_039384, Mlig455_039391

Neo: -

Age: -

 PCDH11X 0.968 - - 0.968 - - -

Mlig455_039384 {REF} {Length: 2836} {Pfam: Cadherin domain [PF00028.19, score=280.0]; Cadherin-like [PF16184.7, score=41.3]; Cadherin prodomain like [PF08758.13, score=28.6]; Cadherin-like [PF08266.14, score=28.1]} {Human: ENSG00000102290, PCDH11X, protocadherin 11 X-linked, [Score=250, Expect=2e-68]; ENSG00000184226, PCDH9, protocadherin 9, [Score=245, Expect=3e-67]; ENSG00000099715, PCDH11Y, protocadherin 11 Y-linked, [Score=244, Expect=6e-67]} {Mouse: ENSMUSG00000055421, Pcdh9, protocadherin 9, [Score=239, Expect=5e-66]; ENSMUSG00000051375, Pcdh1, protocadherin 1, [Score=230, Expect=2e-62]} {Dmel: FBgn0024836, stan, starry night, [Score=205, Expect=9e-54]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=163, Expect=1e-40]} {Smed: dd_Smed_v6_19816_0_1, dd_Smed_v6_19816_0_1, [RH, Score=324, Expect=3e-95]} {RNA1310_41254} {RNA815_60576}

Mlig455_039391 {REF} {Length: 4065} {Pfam: Cadherin domain [PF00028.19, score=279.6]; Cadherin-like [PF16184.7, score=39.6]; Cadherin prodomain like [PF08758.13, score=28.2]; Cadherin-like [PF08266.14, score=25.9]} {Human: ENSG00000102290, PCDH11X, protocadherin 11 X-linked, [Score=257, Expect=9e-70]; ENSG00000099715, PCDH11Y, protocadherin 11 Y-linked, [Score=252, Expect=5e-68]; ENSG00000184226, PCDH9, protocadherin 9, [Score=246, Expect=2e-66]} {Mouse: ENSMUSG00000055421, Pcdh9, protocadherin 9, [Score=240, Expect=1e-64]; ENSMUSG00000051375, Pcdh1, protocadherin 1, [Score=231, Expect=7e-62]} {Dmel: FBgn0024836, stan, starry night, [Score=209, Expect=3e-54]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=166, Expect=4e-41]} {Smed: dd_Smed_v6_19816_0_1, dd_Smed_v6_19816_0_1, [Score=331, Expect=4e-96]} {RNA1310_41254} {RNA815_60576}
34. MligTC455_15701 134 2.79 Mlig455_034847

Neo: -

Age: -

 NEK9 0.967 - - - - 0.967 - Mlig455_034847 {REF} {Length: 3309} {Pfam: Protein kinase domain [PF00069.27, score=196.8]; Regulator of chromosome condensation (RCC1) repeat [PF00415.20, score=167.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=136.5]; Regulator of chromosome condensation (RCC1) repeat [PF13540.8, score=78.8]; Fungal protein kinase [PF17667.3, score=20.1]} {Human: ENSG00000119638, NEK9, NIMA related kinase 9, [RH, Score=743, Expect=0.0]} {Mouse: ENSMUSG00000034290, Nek9, NIMA (never in mitosis gene a)-related expressed kinase 9, [RH, Score=724, Expect=0.0]} {Dmel: FBgn0045980, niki, nimA-like kinase, [Score=308, Expect=2e-91]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=355, Expect=3e-108]} {Smed: dd_Smed_v6_8692_0_1, dd_Smed_v6_8692_0_1, [RH, Score=576, Expect=0.0]} {RNA1509_4066, RNA1509_47408} {RNA1310_4454, RNA1509_47408} {RNA1509_47408, RNA815_1625}
35. MligTC455_53245 111 2.31 Mlig455_009161, Mlig455_009600, Mlig455_027061

Neo: -

Age: logFC(26M/2M)=0.502

Region-enriched R8: 3.893/0.00478

 0.967 - - - 0.967 - -

Mlig455_009161 {REF} {Length: 2794} {Pfam: Mab-21 protein [PF03281.16, score=23.7]} {RNA1509_21275} {RNA1310_18150.1} {RNA815_28013}

Mlig455_009600 {REF} {Length: 2794} {Pfam: Mab-21 protein [PF03281.16, score=23.7]} {RNA1509_21275} {RNA1310_18150.1} {RNA815_28013}

Mlig455_027061 {REF} {Length: 2793} {Pfam: Mab-21 protein [PF03281.16, score=23.7]} {RNA1509_21275} {RNA1310_18150.1} {RNA815_28013}
36. MligTC455_28744 162 3.37 Mlig455_011019

Neo: -

Age: Down-Up-Down

 ITPR1 0.966 - - 0.966 - - - Mlig455_011019 {REF} {Length: 3051} {Pfam: Ion transport protein [PF00520.33, score=20.4]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=116, Expect=1e-26]} {Mouse: ENSMUSG00000030102, Itpr1, inositol 1,4,5-trisphosphate receptor 1, [Score=114, Expect=7e-26]; ENSMUSG00000030592, Ryr1, ryanodine receptor 1, skeletal muscle, [Score=109, Expect=2e-24]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=97.4, Expect=9e-21]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_3814_1_2, dd_Smed_v6_3814_1_2, [Score=447, Expect=6e-150]} {RNA1509_25537} {RNA1310_434.1} {RNA815_10022}
37. MligTC455_17959 100 2.07 Mlig455_007716

Neo: -

Age: Down-Up-Down

 0.965 - - - - 0.965 - Mlig455_007716 {REF} {Length: 2235} {Pfam: Plectin repeat [PF00681.22, score=24.7]} {RNA1509_53557} {RNA1310_11354} {RNA815_18566}
38. MligTC455_22431 1793 37.35 Mlig455_029174, Mlig455_029199, Mlig455_030242

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.492

Region-enriched R4: 1.531/0.03970

 TTLL10 0.965 - - - - 0.965 -

Mlig455_029174 {REF} {Length: 5911} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=174.6]; YheC/D like ATP-grasp [PF14398.8, score=40.2]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.7]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [RH, Score=337, Expect=1e-103]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [RH, Score=334, Expect=1e-102]} {Dmel: FBgn0052238, CG32238, [Score=133, Expect=1e-32]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=119, Expect=2e-28]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [RH, Score=431, Expect=3e-140]} {RNA1509_16250} {RNA1310_5524.1} {RNA815_5887}

Mlig455_029199 {REF} {Length: 3271} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=176.0]; YheC/D like ATP-grasp [PF14398.8, score=41.8]; Sugar-transfer associated ATP-grasp [PF14397.8, score=22.9]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [Score=318, Expect=5e-100]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [Score=317, Expect=1e-99]} {Dmel: FBgn0052238, CG32238, [Score=132, Expect=3e-33]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=119, Expect=5e-29]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [Score=407, Expect=5e-135]} {RNA1509_9701} {RNA1310_5524.2} {RNA815_5887}

Mlig455_030242 {REF} {Length: 4802} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=168.4]; YheC/D like ATP-grasp [PF14398.8, score=37.9]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.6]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [Score=286, Expect=4e-85]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [Score=301, Expect=1e-90]} {Dmel: FBgn0030823, CG8918, [Score=121, Expect=1e-28]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=116, Expect=2e-27]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [Score=377, Expect=9e-120]} {RNA1509_16250, RNA1509_24153} {RNA1310_5524.2, RNA1509_24153} {RNA1509_24153, RNA815_6782}
39. MligTC455_09794 47 0.98 Mlig455_039192

Neo: -

Age: -

Region-enriched R2: 4.286/0.04353

 AKTIP 0.963 - - 0.963 - - - Mlig455_039192 {REF} {Length: 2085} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=32.1]} {Human: ENSG00000166971, AKTIP, AKT interacting protein, [RH, Score=106, Expect=2e-26]} {Mouse: ENSMUSG00000031667, Aktip, thymoma viral proto-oncogene 1 interacting protein, [RH, Score=107, Expect=5e-27]} {Dmel: FBgn0285962, CG46338, [RH, Score=88.2, Expect=3e-20]} {Celegans: WBGene00006714, ubc-19, UBiquitin Conjugating enzyme, [RH, Score=88.2, Expect=4e-20]} {Smed: dd_Smed_v6_3423_0_1, dd_Smed_v6_3423_0_1, [RH, Score=88.2, Expect=1e-20]} {RNA1310_39420.1} {RNA815_30132}
40. MligTC455_19211 107 2.23 Mlig455_052588

Neo: -

Age: -

Region-enriched R8: 3.795/0.01587

 0.963 - - 0.963 - - - Mlig455_052588 {REF} {Length: 2340} {Celegans: WBGene00019180, H10D18.5, [RH, Score=62.4, Expect=6e-11]} {Smed: dd_Smed_v6_10251_0_1, dd_Smed_v6_10251_0_1, [RH, Score=95.9, Expect=2e-23]} {RNA1509_8096} {RNA1310_25906} {RNA815_14581.1}
41. MligTC455_20534 1868 38.91 Mlig455_005305

Neo: -

Age: logFC(26M/2M)=-0.258

 0.963 - - - - 0.963 - Mlig455_005305 {REF} {Length: 2652} {Pfam: UPF0489 domain [PF12640.9, score=37.5]} {Smed: dd_Smed_v6_7217_0_1, dd_Smed_v6_7217_0_1, [RH, Score=53.5, Expect=3e-07]} {RNA1509_26295, RNA1509_3030, RNA1509_45201} {RNA1310_7798.1, RNA1509_26295, RNA1509_3030, RNA1509_45201} {RNA1509_26295, RNA1509_3030, RNA1509_45201, RNA815_2565.1}
42. MligTC455_26774 54 1.12 Mlig455_038949

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.339

 ANO7 0.963 - - 0.963 - - - Mlig455_038949 {REF} {Length: 4653} {Pfam: Calcium-activated chloride channel [PF04547.14, score=519.7]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=243.5]} {Human: ENSG00000146205, ANO7, anoctamin 7, [RH, Score=875, Expect=0.0]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [RH, Score=886, Expect=0.0]} {Dmel: FBgn0038721, subdued, [RH, Score=596, Expect=0.0]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=242, Expect=6e-68]} {Smed: dd_Smed_v6_4761_0_1, dd_Smed_v6_4761_0_1, [RH, Score=1092, Expect=0.0]} {RNA1509_15570} {RNA1310_5583.1} {RNA815_1646.1}
43. MligTC455_32573 34 0.71 Mlig455_050903, Mlig455_067814

Neo: -

Age: Up-Down-Up

 CHRNA2 0.963 - - - - - 0.963

Mlig455_050903 {REF} {Length: 2028} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=157.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=98.7]} {Human: ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=208, Expect=2e-59]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=206, Expect=2e-59]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=204, Expect=3e-57]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=198, Expect=6e-56]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=203, Expect=2e-58]; ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=201, Expect=4e-56]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=199, Expect=3e-56]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=198, Expect=3e-56]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=197, Expect=7e-56]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=202, Expect=1e-57]} {Celegans: WBGene00002974, lev-1, Acetylcholine receptor subunit beta-type lev-1, [Score=194, Expect=1e-54]} {Smed: dd_Smed_v6_10322_0_1, dd_Smed_v6_10322_0_1, [Score=426, Expect=7e-143]} {RNA1509_37874} {RNA1310_43734} {RNA815_13595}

Mlig455_067814 {REF} {Length: 2696} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=158.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=99.0]} {Human: ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=208, Expect=4e-60]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=207, Expect=3e-60]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=203, Expect=3e-57]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=198, Expect=2e-56]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=203, Expect=9e-59]; ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=200, Expect=3e-56]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=199, Expect=6e-57]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=197, Expect=3e-56]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=197, Expect=2e-56]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=202, Expect=2e-58]} {Celegans: WBGene00002974, lev-1, Acetylcholine receptor subunit beta-type lev-1, [Score=194, Expect=3e-55]} {Smed: dd_Smed_v6_10322_0_1, dd_Smed_v6_10322_0_1, [Score=426, Expect=1e-143]} {RNA1509_37874} {RNA1310_43734} {RNA815_13595}
44. MligTC455_52432 75 1.56 Mlig455_019213

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.520

 0.963 - - - - - 0.963 Mlig455_019213 {REF} {Length: 3040} {RNA1310_29981} {RNA815_46279}
45. MligTC455_42077 62 1.3 Mlig455_024098

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.885

 0.962 - - - - - 0.962 Mlig455_024098 {REF} {Length: 615} {TRANSSPLICED} {RNA1509_48241} {RNA1310_44412} {RNA815_29414.2}
46. MligTC455_09259 130 2.7 Mlig455_061607

Neo: -

Age: -

Region-enriched R7: 3.673/0.00705

 TIA1 0.961 - - - - - 0.961 Mlig455_061607 {REF} {Length: 2819} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=130.2]; RNA binding motif [PF08777.13, score=26.6]; RNA recognition motif [PF16367.7, score=26.0]; Cytosolic domain of 10TM putative phosphate transporter [PF14703.8, score=20.2]; Nup53/35/40-type RNA recognition motif [PF14605.8, score=19.1]} {Human: ENSG00000116001, TIA1, TIA1 cytotoxic granule associated RNA binding protein, [Score=193, Expect=8e-57]; ENSG00000151923, TIAL1, TIA1 cytotoxic granule associated RNA binding protein like 1, [Score=186, Expect=5e-54]} {Mouse: ENSMUSG00000071337, Tia1, cytotoxic granule-associated RNA binding protein 1, [Score=191, Expect=4e-56]; ENSMUSG00000030846, Tial1, Tia1 cytotoxic granule-associated RNA binding protein-like 1, [Score=187, Expect=5e-55]} {Dmel: FBgn0085391, trv, trivet, [Score=209, Expect=5e-62]} {Celegans: WBGene00015943, tiar-1, TIA-1/TIAL RNA binding protein homolog, [Score=195, Expect=8e-59]} {Smed: dd_Smed_v6_10924_0_1, dd_Smed_v6_10924_0_1, [Score=281, Expect=4e-91]} {RNA1509_12173} {RNA1310_36610.1} {RNA815_23930}
47. MligTC455_16227 57 1.2 Mlig455_059119

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.809

 0.961 - - - - 0.961 - Mlig455_059119 {REF} {Length: 2862} {Smed: dd_Smed_v6_16150_0_1, dd_Smed_v6_16150_0_1, [RH, Score=95.9, Expect=5e-21]} {RNA1509_34395} {RNA1310_13154} {RNA815_10500}
48. MligTC455_25320 36 0.76 Mlig455_047880

Neo: -

Age: -

 PCLO 0.961 - - - 0.961 - - Mlig455_047880 {REF} {Length: 9411} {Pfam: C2 domain [PF00168.32, score=67.8]; FYVE-type zinc finger [PF02318.18, score=65.1]; Piccolo Zn-finger [PF05715.15, score=28.4]; PDZ domain [PF17820.3, score=21.8]} {Human: ENSG00000186472, PCLO, piccolo presynaptic cytomatrix protein, [RH, Score=119, Expect=9e-26]} {Mouse: ENSMUSG00000061601, Pclo, piccolo (presynaptic cytomatrix protein), [RH, Score=120, Expect=2e-26]} {Dmel: FBgn0053547, Rim, Rab3 interacting molecule, [Score=88.2, Expect=1e-16]} {Celegans: WBGene00004033, pkc-2, Protein kinase C-like 2, [Score=80.5, Expect=1e-14]} {Smed: dd_Smed_v6_9615_0_1, dd_Smed_v6_9615_0_1, [RH, Score=190, Expect=3e-48]} {RNA1509_12949, RNA1509_17082} {RNA1310_4514, RNA1509_12949} {RNA1509_12949, RNA815_4128}
49. MligTC455_27181 505 10.52 Mlig455_033391, Mlig455_033441

Neo: -

Age: logFC(26M/2M)=-0.263

Region-enriched R2: 2.348/0.01526

 TMEM67 0.961 - - - - 0.961 -

Mlig455_033391 {REF} {Length: 5538} {Pfam: Meckelin (Transmembrane protein 67) [PF09773.11, score=724.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=117.4]} {Human: ENSG00000164953, TMEM67, transmembrane protein 67, [RH, Score=528, Expect=1e-165]} {Mouse: ENSMUSG00000049488, Tmem67, transmembrane protein 67, [RH, Score=522, Expect=2e-162]} {Dmel: FBgn0038814, CG15923, [RH, Score=151, Expect=1e-36]} {Celegans: WBGene00018042, mks-3, MecKel-Gruber Syndrome (MKS) homolog, [RH, Score=311, Expect=4e-89]} {Smed: dd_Smed_v6_7765_0_1, dd_Smed_v6_7765_0_1, [RH, Score=554, Expect=3e-176]} {RNA1509_3205} {RNA1310_2827.1} {RNA815_833}

Mlig455_033441 {REF} {Length: 3979} {Pfam: Meckelin (Transmembrane protein 67) [PF09773.11, score=724.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=117.4]} {Human: ENSG00000164953, TMEM67, transmembrane protein 67, [RH, Score=528, Expect=1e-165]} {Mouse: ENSMUSG00000049488, Tmem67, transmembrane protein 67, [RH, Score=522, Expect=2e-162]} {Dmel: FBgn0038814, CG15923, [RH, Score=151, Expect=1e-36]} {Celegans: WBGene00018042, mks-3, MecKel-Gruber Syndrome (MKS) homolog, [RH, Score=311, Expect=4e-89]} {Smed: dd_Smed_v6_7765_0_1, dd_Smed_v6_7765_0_1, [RH, Score=554, Expect=3e-176]} {RNA1509_3205} {RNA1310_2827.1} {RNA815_833}
50. MligTC455_27933 109 2.27 Mlig455_062805

Neo: -

Age: logFC(26M/2M)=0.852

 MYLK 0.961 - - - 0.961 - - Mlig455_062805 {REF} {Length: 5619} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=190.4]; Protein kinase domain [PF00069.27, score=143.5]; Immunoglobulin domain [PF13927.8, score=121.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=80.8]; Immunoglobulin domain [PF13895.8, score=52.2]; Immunoglobulin domain [PF00047.27, score=51.8]; Immunoglobulin V-set domain [PF07686.19, score=38.3]; ABC1 atypical kinase-like domain [PF03109.18, score=21.5]} {Human: ENSG00000065534, MYLK, myosin light chain kinase, [Score=184, Expect=7e-47]; ENSG00000140795, MYLK3, myosin light chain kinase 3, [Score=176, Expect=6e-45]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=187, Expect=6e-48]; ENSMUSG00000022836, Mylk, myosin, light polypeptide kinase, [Score=184, Expect=4e-47]} {Dmel: FBgn0005666, bt, bent, [Score=197, Expect=4e-51]} {Celegans: WBGene00006759, unc-22, Twitchin, [Score=216, Expect=1e-57]} {Smed: dd_Smed_v6_2544_0_1, dd_Smed_v6_2544_0_1, [Score=184, Expect=2e-47]} {RNA1509_411} {RNA1310_1.1} {RNA815_0}
51. MligTC455_42691 104 2.16 Mlig455_042573

Neo: -

Age: -

 ARHGAP18 0.961 - - - 0.961 - - Mlig455_042573 {REF} {Length: 3525} {TRANSSPLICED} {Pfam: RhoGAP domain [PF00620.29, score=81.7]; PH domain [PF00169.31, score=20.8]} {Human: ENSG00000146376, ARHGAP18, Rho GTPase activating protein 18, [Score=139, Expect=2e-33]} {Mouse: ENSMUSG00000039031, Arhgap18, Rho GTPase activating protein 18, [Score=122, Expect=4e-28]} {Dmel: FBgn0039994, conu, conundrum, [Score=70.9, Expect=4e-12]} {Celegans: WBGene00001559, gei-1, GEX Interacting protein, [Score=58.9, Expect=2e-08]} {Smed: dd_Smed_v6_3376_0_1, dd_Smed_v6_3376_0_1, [Score=58.5, Expect=1e-08]} {RNA1509_28435} {RNA1310_13214} {RNA815_12374.1}
52. MligTC455_48954 316 6.59 Mlig455_000336, Mlig455_067936

Neo: -

Age: -

Region-enriched R8: 6.016/0.00000
Region-enriched R7: 4.803/0.00000
Region-enriched R6: 2.001/0.03096

 WNT2 0.961 - - - - - 0.961

Mlig455_000336 {REF} {Length: 2268} {Pfam: wnt family [PF00110.21, score=150.7]} {Human: ENSG00000105989, WNT2, Wnt family member 2, [Score=94.4, Expect=1e-20]; ENSG00000162552, WNT4, Wnt family member 4, [Score=92.8, Expect=3e-20]} {Mouse: ENSMUSG00000010797, Wnt2, wingless-type MMTV integration site family, member 2, [Score=95.1, Expect=4e-21]; ENSMUSG00000036856, Wnt4, wingless-type MMTV integration site family, member 4, [Score=93.2, Expect=2e-20]} {Dmel: FBgn0010453, Wnt4, Wnt oncogene analog 4, [Score=75.5, Expect=3e-14]} {Celegans: WBGene00000857, cwn-1, [Score=95.5, Expect=2e-21]} {Smed: dd_Smed_v6_14391_0_1, dd_Smed_v6_14391_0_1, [RH, Score=137, Expect=4e-36]} {RNA1509_39977} {RNA1310_11459, RNA1509_39977} {RNA1509_39977, RNA815_18855}

Mlig455_067936 {REF} {Length: 2361} {Pfam: wnt family [PF00110.21, score=149.2]} {Human: ENSG00000105989, WNT2, Wnt family member 2, [Score=96.7, Expect=2e-21]; ENSG00000162552, WNT4, Wnt family member 4, [Score=92.0, Expect=6e-20]} {Mouse: ENSMUSG00000010797, Wnt2, wingless-type MMTV integration site family, member 2, [Score=97.4, Expect=7e-22]} {Dmel: FBgn0010453, Wnt4, Wnt oncogene analog 4, [Score=75.5, Expect=3e-14]} {Celegans: WBGene00000857, cwn-1, [Score=96.3, Expect=1e-21]} {Smed: dd_Smed_v6_14391_0_1, dd_Smed_v6_14391_0_1, [RH, Score=133, Expect=7e-35]} {RNA1509_39977} {RNA1310_11459} {RNA815_18855}
53. MligTC455_53662 2784 58 Mlig455_007977, Mlig455_015600

Neo: -

Age: logFC(26M/2M)=-0.407

 0.961 - - - - - 0.961

Mlig455_007977 {REF} {Length: 2162} {Smed: dd_Smed_v6_1161_1_1, dd_Smed_v6_1161_1_1, [RH, Score=68.6, Expect=5e-13]} {RNA1509_2354, RNA1509_33456} {RNA1310_13288.1, RNA1509_33456} {RNA1509_33456, RNA815_8569}

Mlig455_015600 {REF} {Length: 1981} {Smed: dd_Smed_v6_1161_1_1, dd_Smed_v6_1161_1_1, [RH, Score=68.6, Expect=5e-13]} {RNA1509_10769, RNA1509_2354, RNA1509_38909, RNA1509_39678} {RNA1310_13288.1, RNA1509_10769, RNA1509_2354, RNA1509_38909, RNA1509_39678} {RNA1509_10769, RNA1509_2354, RNA1509_38909, RNA1509_39678, RNA815_8569}
54. MligTC455_15228 38 0.8 Mlig455_023876

Neo: -

Age: -

 0.96 - - - - - 0.960 Mlig455_023876 {REF} {Length: 827} {RNA1509_31914} {RNA1310_102040} {RNA815_22831}
55. MligTC455_32317 1546 32.21 Mlig455_039677

Neo: -

Age: logFC(26M/2M)=-0.274

 BEST4 0.96 - - - - 0.960 - Mlig455_039677 {REF} {Length: 3379} {Pfam: Bestrophin, RFP-TM, chloride channel [PF01062.23, score=182.9]} {Human: ENSG00000142959, BEST4, bestrophin 4, [Score=205, Expect=9e-60]} {Mouse: ENSMUSG00000020169, Best3, bestrophin 3, [Score=193, Expect=8e-54]; ENSMUSG00000052819, Best2, bestrophin 2, [Score=191, Expect=3e-54]} {Dmel: FBgn0040238, Best1, Bestrophin 1, [Score=227, Expect=3e-66]} {Celegans: WBGene00015288, best-4, Bestrophin homolog, [Score=180, Expect=5e-50]} {Smed: dd_Smed_v6_8073_0_1, dd_Smed_v6_8073_0_1, [Score=359, Expect=7e-120]} {RNA1509_15539, RNA1509_25951, RNA1509_8648} {RNA1310_8340, RNA1509_15539, RNA1509_25951, RNA1509_8648} {RNA1509_15539, RNA1509_25951, RNA1509_8648, RNA815_2922.1}
56. MligTC455_44160 159 3.32 Mlig455_054300

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.772

 0.96 - - - - 0.960 - Mlig455_054300 {REF} {Length: 1875} {Pfam: RAM signalling pathway protein [PF10428.11, score=19.5]} {RNA1509_25869, RNA1509_28395, RNA1509_50016} {RNA1310_9357.1, RNA1509_25869, RNA1509_50016} {RNA1509_25869, RNA1509_50016, RNA815_10341}
57. MligTC455_25785 47 0.97 Mlig455_046276

Neo: -

Age: -

 0.959 - - - - - 0.959 Mlig455_046276 {REF} {Length: 1627} {RNA1509_22707} {RNA1310_33596.2} {RNA815_24119.2}
58. MligTC455_30138 465 9.69 Mlig455_038022, Mlig455_068400

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.522

Region-enriched R2: 2.607/0.01918

 HEATR4 0.959 - - - - 0.959 -

Mlig455_038022 {REF} {Length: 4854} {TRANSSPLICED} {Pfam: HEAT repeats [PF13646.8, score=77.9]; HEAT repeat [PF02985.24, score=45.7]; HEAT-like repeat [PF13513.8, score=26.2]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=18.9]} {Human: ENSG00000187105, HEATR4, HEAT repeat containing 4, [RH, Score=339, Expect=3e-98]} {Mouse: ENSMUSG00000090843, Heatr4, HEAT repeat containing 4, [RH, Score=327, Expect=8e-95]} {Smed: dd_Smed_v6_16127_0_1, dd_Smed_v6_16127_0_1, [RH, Score=460, Expect=8e-141]} {RNA1509_8516} {RNA1310_8186} {RNA815_1423.1}

Mlig455_068400 {REF} {Length: 4848} {TRANSSPLICED} {Pfam: HEAT repeats [PF13646.8, score=88.8]; HEAT repeat [PF02985.24, score=45.7]; HEAT-like repeat [PF13513.8, score=25.9]} {Human: ENSG00000187105, HEATR4, HEAT repeat containing 4, [RH, Score=340, Expect=1e-98]} {Mouse: ENSMUSG00000090843, Heatr4, HEAT repeat containing 4, [RH, Score=328, Expect=2e-95]} {Smed: dd_Smed_v6_16127_0_1, dd_Smed_v6_16127_0_1, [RH, Score=460, Expect=5e-141]} {RNA1509_8516} {RNA1310_8186} {RNA815_1423.1}
59. MligTC455_36404 165 3.45 Mlig455_047919

Neo: -

Age: Down-Up-Down

 MRPL48 0.959 - - 0.959 - - - Mlig455_047919 {REF} {Length: 1883} {TRANSSPLICED} {Pfam: Ribosomal protein S10p/S20e [PF00338.24, score=45.7]} {Human: ENSG00000175581, MRPL48, mitochondrial ribosomal protein L48, [RH, Score=52.4, Expect=5e-08]} {Mouse: ENSMUSG00000030706, Mrpl48, mitochondrial ribosomal protein L48, [RH, Score=48.1, Expect=9e-07]} {Dmel: FBgn0031357, mRpL48, mitochondrial ribosomal protein L48, [RH, Score=80.5, Expect=5e-19]} {Smed: dd_Smed_v6_4587_0_1, dd_Smed_v6_4587_0_1, [RH, Score=73.9, Expect=1e-16]} {RNA1509_18137, RNA1509_51510} {RNA1310_41454, RNA1509_18137, RNA1509_51510} {RNA1509_18137, RNA1509_51510, RNA815_12402}
60. MligTC455_42545 32 0.67 Mlig455_002655

Neo: -

Age: -

 0.959 - - - - - 0.959 Mlig455_002655 {REF} {Length: 1324} {NoTransDecoderORF} {RNA1509_54267} {RNA1310_33758} {RNA815_263}
61. MligTC455_07051 26 0.54 Mlig455_024162, Mlig455_047642

Neo: -

Age: -

 0.958 - - - - - 0.958

Mlig455_024162 {REF} {Length: 2495} {Pfam: SET domain [PF00856.30, score=35.1]; C2H2-type zinc-finger domain [PF13909.8, score=22.1]} {RNA1310_131883} {RNA815_45891}

Mlig455_047642 {REF} {Length: 799} {RNA1310_131883}
62. MligTC455_24093 62 1.29 Mlig455_059190

Neo: -

Age: Up-Down-Down

Region-enriched R6: 4.112/0.00048

 0.957 - - - - - 0.957 Mlig455_059190 {REF} {Length: 3731} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=136.4]} {Celegans: WBGene00016064, acd-1, [Score=49.3, Expect=7e-06]} {Smed: dd_Smed_v6_15195_0_1, dd_Smed_v6_15195_0_1, [Score=225, Expect=2e-66]} {RNA1509_1151} {RNA1310_43459} {RNA815_50348}
63. MligTC455_03593 21 0.43 Mlig455_054695

Neo: -

Age: -

 0.956 - - - - - 0.956 Mlig455_054695 {REF} {Length: 1093} {NoTransDecoderORF} {RNA1509_46835} {RNA1310_16754} {RNA815_21965}
64. MligTC455_33123 64 1.33 Mlig455_063455

Neo: -

Age: -

 SYP 0.956 - - 0.956 - - - Mlig455_063455 {REF} {Length: 2098} {Pfam: Membrane-associating domain [PF01284.25, score=30.0]} {Human: ENSG00000102003, SYP, synaptophysin, [RH, Score=74.7, Expect=5e-17]} {Mouse: ENSMUSG00000031144, Syp, synaptophysin, [Score=72.8, Expect=7e-16]} {Smed: dd_Smed_v6_682_0_1, dd_Smed_v6_682_0_1, [Score=87.4, Expect=3e-22]} {RNA1509_20189} {RNA1310_9076} {RNA815_6504}
65. MligTC455_33131 549 11.45 Mlig455_022594, Mlig455_026005, Mlig455_070429

Neo: Germline

Age: logFC(26M/2M)=-0.432

 KY 0.956 - - - - 0.956 -

Mlig455_022594 {REF} {Length: 667} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_18119} {RNA815_4493}

Mlig455_026005 {REF} {Length: 5002} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=111, Expect=1e-24]} {RNA1509_11170} {RNA1310_2597.1} {RNA815_17158}

Mlig455_070429 {REF} {Length: 5697} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=97.4, Expect=5e-20]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=96.7, Expect=6e-20]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=113, Expect=4e-25]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=113, Expect=3e-25]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=113, Expect=4e-25]} {RNA1509_11170, RNA1509_29877} {RNA1310_2597.1, RNA1509_11170, RNA1509_29877} {RNA1509_11170, RNA1509_29877, RNA815_3609}
66. MligTC455_20517 89 1.86 Mlig455_023814

Neo: -

Age: logFC(26M/2M)=0.507

 QRSL1 0.955 - - 0.955 - - - Mlig455_023814 {REF} {Length: 3292} {TRANSSPLICED} {Pfam: Amidase [PF01425.23, score=219.5]} {Human: ENSG00000130348, QRSL1, QRSL1, glutaminyl-tRNA amidotransferase subunit A, [Score=104, Expect=3e-24]} {Mouse: ENSMUSG00000019863, Qrsl1, glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1, [Score=103, Expect=5e-23]} {Dmel: FBgn0260779, GatA, Glutamyl-tRNA amidotransferase, subunit A, [Score=105, Expect=5e-24]} {Celegans: WBGene00021508, Y41D4A.6, Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, [Score=106, Expect=2e-24]} {Smed: dd_Smed_v6_12029_0_1, dd_Smed_v6_12029_0_1, [Score=96.3, Expect=3e-21]} {RNA1310_26342} {RNA815_31425}
67. MligTC455_18802 612 12.75 Mlig455_050495

Neo: -

Age: logFC(26M/2M)=-0.313

Region-enriched R2: 1.656/0.00269

 CLIP2 0.954 - - - - 0.954 - Mlig455_050495 {REF} {Length: 2826} {TRANSSPLICED} {Pfam: CAP-Gly domain [PF01302.27, score=65.4]; Homeobox associated leucine zipper [PF02183.20, score=23.1]; TSC-22/dip/bun family [PF01166.20, score=21.0]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=57.8, Expect=6e-08]; ENSG00000130779, CLIP1, CAP-Gly domain containing linker protein 1, [Score=57.0, Expect=1e-07]; ENSG00000135837, CEP350, centrosomal protein 350, [Score=56.2, Expect=2e-07]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=55.5, Expect=2e-07]; ENSMUSG00000049550, Clip1, CAP-GLY domain containing linker protein 1, [Score=53.9, Expect=7e-07]; ENSMUSG00000033671, Cep350, centrosomal protein 350, [Score=53.1, Expect=1e-06]} {Dmel: FBgn0020503, CLIP-190, Cytoplasmic linker protein 190, [Score=56.2, Expect=6e-08]} {Smed: dd_Smed_v6_12415_0_2, dd_Smed_v6_12415_0_2, [RH, Score=161, Expect=5e-42]} {RNA1509_7942} {RNA1310_6547.1, RNA1509_7942} {RNA1509_7942, RNA815_18657}
68. MligTC455_48006 701 14.61 Mlig455_007273, Mlig455_031838, Mlig455_068306

Neo: -

Age: -

Region-specific R2: 2.969

Region-enriched R2: 2.942/0.00000

 DAG1 0.954 - - - - 0.954 -

Mlig455_007273 {REF} {Length: 4574} {Pfam: Dystroglycan (Dystrophin-associated glycoprotein 1) [PF05454.13, score=33.4]; Alpha-Dystroglycan N-terminal domain 2 [PF18424.3, score=23.0]; TMEM154 protein family [PF15102.8, score=20.3]} {Smed: dd_Smed_v6_11814_0_1, dd_Smed_v6_11814_0_1, [Score=75.5, Expect=2e-13]} {RNA1509_12492} {RNA1310_1589.1} {RNA815_11235}

Mlig455_031838 {REF} {Length: 4722} {TRANSSPLICED} {Pfam: Dystroglycan (Dystrophin-associated glycoprotein 1) [PF05454.13, score=33.3]; Alpha-Dystroglycan N-terminal domain 2 [PF18424.3, score=32.4]; TMEM154 protein family [PF15102.8, score=20.2]} {Human: ENSG00000173402, DAG1, dystroglycan 1, [Score=58.9, Expect=6e-08]} {Mouse: ENSMUSG00000039952, Dag1, dystroglycan 1, [Score=57.8, Expect=9e-08]} {Smed: dd_Smed_v6_11814_0_1, dd_Smed_v6_11814_0_1, [Score=95.9, Expect=1e-19]} {RNA1509_12492} {RNA1310_1589.1} {RNA815_11235}

Mlig455_068306 {REF} {Length: 4731} {TRANSSPLICED} {Pfam: Dystroglycan (Dystrophin-associated glycoprotein 1) [PF05454.13, score=33.3]; Alpha-Dystroglycan N-terminal domain 2 [PF18424.3, score=32.4]; TMEM154 protein family [PF15102.8, score=20.2]} {Human: ENSG00000173402, DAG1, dystroglycan 1, [Score=58.5, Expect=7e-08]} {Mouse: ENSMUSG00000039952, Dag1, dystroglycan 1, [Score=57.4, Expect=1e-07]} {Smed: dd_Smed_v6_11814_0_1, dd_Smed_v6_11814_0_1, [Score=97.8, Expect=2e-20]} {RNA1509_12492} {RNA1310_1589.1, RNA1509_12492} {RNA1509_12492, RNA815_11235}
69. MligTC455_06705 80 1.68 Mlig455_019480, Mlig455_060538, Mlig455_066890

Neo: -

Age: Up-Down-Up

 TLR7 0.953 - - - - - 0.953

Mlig455_019480 {REF} {Length: 3308} {Pfam: Leucine rich repeat [PF13855.8, score=88.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=59.8]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=22.1]; TIR domain [PF01582.22, score=21.8]; Leucine Rich Repeat [PF00560.35, score=20.7]; TIR domain [PF13676.8, score=19.8]; Leucine-rich repeat [PF14580.8, score=19.6]} {Human: ENSG00000196664, TLR7, toll like receptor 7, [Score=80.9, Expect=6e-15]} {Mouse: ENSMUSG00000044583, Tlr7, toll-like receptor 7, [Score=79.3, Expect=1e-14]} {Dmel: FBgn0034083, lbk, lambik, [Score=72.0, Expect=2e-12]} {Celegans: WBGene00022129, lron-11, 1D304; ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=57.8, Expect=2e-08]} {RNA1509_25920} {RNA1310_57209} {RNA815_36862}

Mlig455_060538 {REF} {Length: 2657} {Pfam: TIR domain [PF13676.8, score=22.8]; TIR domain [PF01582.22, score=19.9]} {Human: ENSG00000196664, TLR7, toll like receptor 7, [Score=51.2, Expect=8e-07]} {Mouse: ENSMUSG00000044583, Tlr7, toll-like receptor 7, [Score=55.5, Expect=3e-08]} {RNA1509_25920} {RNA1310_57209} {RNA815_36862}

Mlig455_066890 {REF} {Length: 3474} {Pfam: Leucine rich repeat [PF13855.8, score=102.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=70.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=37.2]; Leucine-rich repeat [PF14580.8, score=23.1]; TIR domain [PF01582.22, score=20.6]; TIR domain [PF13676.8, score=19.5]} {Human: ENSG00000196664, TLR7, toll like receptor 7, [RH, Score=93.2, Expect=1e-18]} {Mouse: ENSMUSG00000044583, Tlr7, toll-like receptor 7, [RH, Score=90.1, Expect=7e-18]} {Dmel: FBgn0036494, Toll-6, [Score=72.4, Expect=2e-12]} {Celegans: WBGene00006366, sym-1, SYM-1 protein, [Score=58.2, Expect=2e-08]} {RNA1509_25920} {RNA1310_49916} {RNA815_36862}
70. MligTC455_17267 266 5.55 Mlig455_017106

Neo: -

Age: logFC(26M/2M)=-0.337

 OTOP2 0.953 - - - - 0.953 - Mlig455_017106 {REF} {Length: 3746} {Pfam: Otopetrin [PF03189.15, score=249.6]} {Human: ENSG00000183034, OTOP2, otopetrin 2, [Score=58.9, Expect=2e-08]} {Mouse: ENSMUSG00000050201, Otop2, otopetrin 2, [Score=68.2, Expect=2e-11]} {Dmel: FBgn0259150, CG42265, [Score=181, Expect=4e-47]} {Celegans: WBGene00017449, otpl-3, OToPetrin-Like, [Score=114, Expect=2e-26]} {Smed: dd_Smed_v6_13612_0_2, dd_Smed_v6_13612_0_2, [RH, Score=297, Expect=2e-91]} {RNA1509_17427} {RNA1310_8650, RNA1509_17427} {RNA1509_17427, RNA815_9942}
71. MligTC455_42821 155 3.22 Mlig455_040440

Neo: -

Age: -

 LARGE1 0.953 - - - - 0.953 - Mlig455_040440 {REF} {Length: 5152} {TRANSSPLICED} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=181.1]; Glycosyl transferase family 8 [PF01501.22, score=52.6]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=649, Expect=0.0]; ENSG00000165905, LARGE2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=620, Expect=0.0]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [RH, Score=646, Expect=0.0]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [RH, Score=622, Expect=0.0]} {Dmel: FBgn0032457, CG15483, [RH, Score=67.8, Expect=1e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [RH, Score=304, Expect=1e-93]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [RH, Score=484, Expect=6e-165]} {RNA1509_51185} {RNA1310_11436, RNA1509_51185} {RNA1509_51185, RNA815_10031}
72. MligTC455_10359 45 0.93 Mlig455_001092

Neo: -

Age: -

 0.952 - - - - - 0.952 Mlig455_001092 {REF} {Length: 1830} {TRANSSPLICED} {RNA1310_35838.1} {RNA815_17439}
73. MligTC455_25945 25 0.53 Mlig455_019546

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.743

Region-enriched R4: 3.955/0.01696

 MX2 0.952 - - - 0.952 - - Mlig455_019546 {REF} {Length: 3219} {Pfam: Dynamin central region [PF01031.22, score=131.1]; Dynamin family [PF00350.25, score=71.6]; Dynamin GTPase effector domain [PF02212.20, score=28.1]; Laminin Domain I [PF06008.16, score=18.4]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=204, Expect=1e-56]; ENSG00000157601, MX1, MX dynamin like GTPase 1, [Score=196, Expect=6e-54]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=187, Expect=5e-51]} {Dmel: FBgn0003392, shi, shibire, [Score=114, Expect=4e-26]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=119, Expect=1e-27]} {Smed: dd_Smed_v6_6863_0_4, dd_Smed_v6_6863_0_4, [Score=112, Expect=1e-25]} {RNA1509_17853} {RNA1310_5329.1} {RNA815_1588.1}
74. MligTC455_28483 912 19 Mlig455_056019

Neo: -

Age: -

Region-enriched R2: 1.652/0.01432

 XPO4 0.952 - - - - 0.952 - Mlig455_056019 {REF} {Length: 4372} {TRANSSPLICED} {Human: ENSG00000132953, XPO4, exportin 4, [RH, Score=241, Expect=2e-64]} {Mouse: ENSMUSG00000021952, Xpo4, exportin 4, [RH, Score=241, Expect=7e-65]} {Smed: dd_Smed_v6_10330_0_1, dd_Smed_v6_10330_0_1, [RH, Score=72.4, Expect=1e-12]} {RNA1509_11967, RNA1509_55558} {RNA1310_2509.1, RNA1509_55558} {RNA1509_55558, RNA815_8640}
75. MligTC455_32569 388 8.09 Mlig455_037270

Neo: -

Age: -

 IRAK4 0.952 - - - - 0.952 - Mlig455_037270 {REF} {Length: 3195} {Pfam: Protein kinase domain [PF00069.27, score=132.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=110.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.4]} {Human: ENSG00000198001, IRAK4, interleukin 1 receptor associated kinase 4, [Score=78.6, Expect=1e-14]} {Mouse: ENSMUSG00000059883, Irak4, interleukin-1 receptor-associated kinase 4, [Score=82.4, Expect=5e-16]} {Dmel: FBgn0010441, pll, pelle, [Score=75.5, Expect=8e-14]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_9065_0_1, dd_Smed_v6_9065_0_1, [Score=67.8, Expect=4e-12]} {RNA1509_57751, RNA1509_59099} {RNA1310_29366, RNA1509_57751, RNA1509_59099} {RNA1509_57751, RNA1509_59099, RNA815_24983}
76. MligTC455_42273 272 5.67 Mlig455_039400

Neo: -

Age: Up-Down-Down

Region-enriched R8: 6.215/0.00000

 RASGRF1 0.952 - - 0.952 - - - Mlig455_039400 {REF} {Length: 5341} {Pfam: RasGEF domain [PF00617.21, score=186.0]; RhoGEF domain [PF00621.22, score=114.0]; PH domain [PF00169.31, score=70.4]; RasGEF N-terminal motif [PF00618.22, score=67.2]; Pleckstrin homology domain [PF15413.8, score=23.5]} {Human: ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [RH, Score=752, Expect=0.0]; ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [RH, Score=741, Expect=0.0]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=153, Expect=5e-37]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=115, Expect=1e-25]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [RH, Score=1133, Expect=0.0]} {RNA1509_54715} {RNA1310_10415, RNA1509_54715} {RNA1509_54715, RNA815_14434}
77. MligTC455_53387 188 3.91 Mlig455_025116

Neo: -

Age: -

 0.952 - - - - 0.952 - Mlig455_025116 {REF} {Length: 2443} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF13410.8, score=21.7]} {RNA1509_15321, RNA1509_30948, RNA1509_38855} {RNA1310_18756.1, RNA1509_15321, RNA1509_30948, RNA1509_38855} {RNA1509_15321, RNA1509_30948, RNA1509_38855, RNA815_4170.1}
78. MligTC455_00722 98 2.04 Mlig455_029527

Neo: -

Age: -

 0.951 - - - - - 0.951 Mlig455_029527 {REF} {Length: 63} {NoTransDecoderORF}
79. MligTC455_23839 23 0.48 Mlig455_033252

Neo: -

Age: -

 0.951 - - 0.951 - - - Mlig455_033252 {REF} {Length: 5293} {RNA1509_19415} {RNA1310_2520.1} {RNA815_1536.1}
80. MligTC455_39765 175 3.65 Mlig455_027660

Neo: Germline

Age: Up-Down-Down

 0.951 - - 0.951 - - - Mlig455_027660 {REF} {Length: 3087} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=22.8]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=83.6, Expect=8e-18]} {RNA1509_22260} {RNA1310_8440} {RNA815_5721}
81. MligTC455_43285 112 2.34 Mlig455_006643

Neo: -

Age: -

 ARMC3 0.951 - - - - 0.951 - Mlig455_006643 {REF} {Length: 3011} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=100.6]; Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=95.9]; HEAT repeats [PF13646.8, score=72.3]; HEAT repeat [PF02985.24, score=52.3]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=40.1]; HEAT-like repeat [PF13513.8, score=40.0]; V-ATPase subunit H [PF11698.10, score=39.8]; Armadillo-like [PF04826.15, score=29.7]; Interferon-related developmental regulator (IFRD) [PF05004.15, score=18.7]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [RH, Score=533, Expect=3e-176]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [RH, Score=504, Expect=2e-165]} {Dmel: FBgn0033794, CG13326, [Score=57.4, Expect=6e-08]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [RH, Score=752, Expect=0.0]} {RNA1509_14962, RNA1509_42538, RNA1509_58062} {RNA1310_4998.1, RNA1509_14962, RNA1509_42538} {RNA1509_14962, RNA1509_42538, RNA815_8459}
82. MligTC455_46429 48 1 Mlig455_042128

Neo: -

Age: -

 0.951 - - - - 0.951 - Mlig455_042128 {REF} {Length: 1428} {Pfam: F5/8 type C domain [PF00754.27, score=33.1]} {RNA1310_65361} {RNA815_33677}
83. MligTC455_27708 1033 21.52 Mlig455_058740

Neo: -

Age: Down-Down-Up

 TCTN1 0.95 - - - - 0.950 - Mlig455_058740 {REF} {Length: 4264} {Pfam: Protein of unknown function (DUF1619) [PF07773.13, score=180.3]} {Human: ENSG00000204852, TCTN1, tectonic family member 1, [RH, Score=140, Expect=1e-34]} {Mouse: ENSMUSG00000038593, Tctn1, tectonic family member 1, [RH, Score=128, Expect=8e-31]} {Smed: dd_Smed_v6_14210_0_1, dd_Smed_v6_14210_0_1, [Score=82.4, Expect=2e-16]} {RNA1509_21328, RNA1509_2978, RNA1509_56923, RNA1509_7408} {RNA1310_313, RNA1509_2978, RNA1509_56923, RNA1509_7408} {RNA1509_2978, RNA1509_56923, RNA1509_7408, RNA815_1107}
84. MligTC455_43963 1010 21.04 Mlig455_015437

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.083/0.01168

 0.95 - - - - 0.950 - Mlig455_015437 {REF} {Length: 612} {RNA1509_32160} {RNA1310_60746, RNA1509_32160} {RNA1509_32160, RNA815_30740}
85. MligTC455_44536 178 3.71 Mlig455_002956

Neo: -

Age: -

 ALX3 0.95 - - - - 0.950 - Mlig455_002956 {REF} {Length: 2217} {Pfam: Homeodomain [PF00046.31, score=82.6]} {Human: ENSG00000156150, ALX3, ALX homeobox 3, [RH, Score=135, Expect=5e-36]; ENSG00000052850, ALX4, ALX homeobox 4, [RH, Score=134, Expect=4e-35]; ENSG00000180318, ALX1, ALX homeobox 1, [RH, Score=129, Expect=6e-34]} {Mouse: ENSMUSG00000040310, Alx4, aristaless-like homeobox 4, [RH, Score=134, Expect=4e-35]; ENSMUSG00000014603, Alx3, aristaless-like homeobox 3, [RH, Score=134, Expect=1e-35]; ENSMUSG00000036602, Alx1, ALX homeobox 1, [RH, Score=129, Expect=1e-34]} {Dmel: FBgn0020617, Rx, Retinal Homeobox, [RH, Score=119, Expect=8e-29]} {Celegans: WBGene00044330, alr-1, AristaLess (Drosophila homeodomain) Related, [RH, Score=116, Expect=4e-29]} {Smed: dd_Smed_v6_16955_0_1, dd_Smed_v6_16955_0_1, [RH, Score=132, Expect=7e-35]} {RNA1310_34642} {RNA815_45742}
86. MligTC455_50558 173 3.61 Mlig455_005169

Neo: -

Age: Up-Up-Down

 ELP2 0.95 - - 0.950 - - - Mlig455_005169 {REF} {Length: 3996} {Pfam: WD domain, G-beta repeat [PF00400.34, score=78.5]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=26.4]} {Human: ENSG00000134759, ELP2, elongator acetyltransferase complex subunit 2, [RH, Score=317, Expect=3e-96]} {Mouse: ENSMUSG00000024271, Elp2, elongator acetyltransferase complex subunit 2, [RH, Score=315, Expect=6e-96]} {Dmel: FBgn0033540, Elp2, Elongator complex protein 2, [Score=339, Expect=1e-105]} {Celegans: WBGene00013738, elpc-2, ELongator complex Protein Component, [RH, Score=255, Expect=2e-74]} {Smed: dd_Smed_v6_8224_0_1, dd_Smed_v6_8224_0_1, [RH, Score=260, Expect=2e-76]} {RNA1509_24068} {RNA1310_6574.1, RNA1509_24068} {RNA1509_24068, RNA815_5329}

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