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Results for MligTC455_12032

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_12032 92 1.91 Mlig455_044477

Neo: -

Age: -

KCNIP1 Mlig455_044477 {REF} {Length: 1077} {Pfam: EF hand [PF00036.34, score=60.1]; EF-hand domain [PF13405.8, score=57.2]; EF-hand domain pair [PF13499.8, score=54.7]; EF-hand domain pair [PF13833.8, score=47.2]; EF hand [PF13202.8, score=43.0]} {Human: ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=169, Expect=9e-52]; ENSG00000120049, KCNIP2, potassium voltage-gated channel interacting protein 2, [Score=164, Expect=7e-49]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=170, Expect=2e-52]} {Dmel: FBgn0039380, CG5890, [Score=150, Expect=5e-45]} {Celegans: WBGene00008998, ncs-4, Neuronal Calcium Sensor family, [RH, Score=121, Expect=1e-33]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=163, Expect=6e-50]} {RNA1310_40826} {RNA815_29104}

Cumulative graph for MligTC455_12032

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.284 1.954 1.00000 1.00000
RegionR2 3.684 1.954 0.01761 0.14158
RegionR3 1.981 1.954 0.07856 0.49621
RegionR4 0.651 1.954 0.48915 0.81623
RegionR5 -1.181 1.954 0.88810 1.00000
RegionR6 -3.568 1.954 1.00000 1.00000
RegionR7 2.296 1.954 0.09512 0.59019
RegionR8 -2.579 1.954 0.99968 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.809 1.954 0.99995 1.00000
RegenerationR2 -0.728 1.954 0.16907 0.60803
RegenerationR3 -0.076 1.954 0.81506 0.98627
RegenerationR4 -0.188 1.954 0.92107 1.00000
RegenerationR5 -0.591 1.954 0.77738 0.98095
RegenerationR6 2.177 1.954 0.21257 0.55628
RegenerationBL -2.515 1.954 0.99977 1.00000
RegenerationTP -3.411 1.954 0.99976 1.00000


Genes with expression patterns similar to MligTC455_12032

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_12032 92 1.91 Mlig455_044477

Neo: -

Age: -

KCNIP1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_044477 {REF} {Length: 1077} {Pfam: EF hand [PF00036.34, score=60.1]; EF-hand domain [PF13405.8, score=57.2]; EF-hand domain pair [PF13499.8, score=54.7]; EF-hand domain pair [PF13833.8, score=47.2]; EF hand [PF13202.8, score=43.0]} {Human: ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=169, Expect=9e-52]; ENSG00000120049, KCNIP2, potassium voltage-gated channel interacting protein 2, [Score=164, Expect=7e-49]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=170, Expect=2e-52]} {Dmel: FBgn0039380, CG5890, [Score=150, Expect=5e-45]} {Celegans: WBGene00008998, ncs-4, Neuronal Calcium Sensor family, [RH, Score=121, Expect=1e-33]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=163, Expect=6e-50]} {RNA1310_40826} {RNA815_29104}
2. MligTC455_25556 160 3.33 Mlig455_041382

Neo: -

Age: -

Region-specific R2: 5.503

Region-enriched R2: 4.706/0.00082

4.382 0.836 0.722 - 0.896 0.989 0.939 Mlig455_041382 {REF} {Length: 1197} {RNA1509_55439} {RNA1310_65119, RNA1509_55439} {RNA1509_55439, RNA815_36098.2}
3. MligTC455_42777 776 16.16 Mlig455_061330, Mlig455_061351, Mlig455_062681

Neo: -

Age: -

Region-enriched R2: 2.412/0.00354

Regeneration-downregulated BL: -7.472

Regeneration-depleted BL: -7.472

HPCA, KCNIP3 4.223 - 0.838 0.833 0.797 0.975 0.780

Mlig455_061330 {REF} {Length: 3398} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=54.3]; EF hand [PF00036.34, score=44.6]; EF-hand domain [PF13405.8, score=40.1]; EF hand [PF13202.8, score=22.1]} {Human: ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=53.9, Expect=1e-08]; ENSG00000138472, GUCA1C, guanylate cyclase activator 1C, [Score=52.4, Expect=2e-08]} {Mouse: ENSMUSG00000079056, Kcnip3, Kv channel interacting protein 3, calsenilin, [Score=51.6, Expect=4e-08]} {Dmel: FBgn0265595, CG44422, [Score=53.1, Expect=1e-08]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=48.5, Expect=2e-07]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [Score=47.4, Expect=3e-07]} {RNA1509_44520, RNA1509_55897} {RNA1310_41409.1, RNA1509_55897} {RNA1509_55897, RNA815_23006}

Mlig455_061351 {REF} {Length: 2885} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=53.9]; EF hand [PF00036.34, score=44.8]; EF-hand domain [PF13405.8, score=40.1]; EF hand [PF13202.8, score=22.3]} {Human: ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=53.9, Expect=1e-08]; ENSG00000138472, GUCA1C, guanylate cyclase activator 1C, [Score=53.1, Expect=1e-08]} {Mouse: ENSMUSG00000079056, Kcnip3, Kv channel interacting protein 3, calsenilin, [Score=51.6, Expect=5e-08]} {Dmel: FBgn0265595, CG44422, [Score=49.7, Expect=2e-07]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=48.9, Expect=1e-07]} {RNA1509_55897} {RNA1310_41409.2} {RNA815_23006}

Mlig455_062681 {REF} {Length: 1756} {Pfam: EF-hand domain pair [PF13499.8, score=54.6]; EF hand [PF00036.34, score=44.6]; EF-hand domain [PF13405.8, score=40.1]; EF hand [PF13202.8, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.1]} {Human: ENSG00000121905, HPCA, hippocalcin, [Score=57.0, Expect=4e-10]; ENSG00000104490, NCALD, neurocalcin delta, [Score=55.5, Expect=1e-09]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=54.3, Expect=4e-09]} {Mouse: ENSMUSG00000020907, Rcvrn, recoverin, [Score=57.0, Expect=3e-10]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=57.0, Expect=3e-10]; ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=55.5, Expect=9e-10]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=54.7, Expect=2e-09]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=53.9, Expect=2e-09]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=48.5, Expect=2e-07]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=51.2, Expect=1e-08]} {RNA1509_44520} {RNA1310_41409.1, RNA1509_44520} {RNA1509_44520, RNA815_23006}
4. MligTC455_47393 241 5.03 Mlig455_008718, Mlig455_063579

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.683/0.00849

CALM2 3.61 - 0.880 - 0.909 0.978 0.843

Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211}

Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211}
5. MligTC455_53546 130 2.72 Mlig455_013326, Mlig455_013334

Neo: -

Age: -

Region-enriched R2: 6.753/0.01892

MMP9 3.559 - 0.978 - 0.900 0.851 0.830

Mlig455_013326 {REF} {Length: 1449} {Pfam: Fibronectin type II domain [PF00040.21, score=92.5]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=82.4, Expect=1e-16]; ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [RH, Score=78.6, Expect=2e-15]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [RH, Score=138, Expect=3e-38]} {RNA1310_38631} {RNA815_51136}

Mlig455_013334 {REF} {Length: 1398} {Pfam: Fibronectin type II domain [PF00040.21, score=92.1]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=84.0, Expect=4e-17]} {Smed: dd_Smed_v6_12601_0_1, dd_Smed_v6_12601_0_1, [RH, Score=140, Expect=2e-38]} {RNA1310_38631} {RNA815_51136}
6. MligTC455_25928 181 3.78 Mlig455_006534, Mlig455_006538, Mlig455_006649, Mlig455_006700

Neo: -

Age: logFC(26M/2M)=-0.528

Region-specific R2: 7.256

Region-enriched R2: 5.788/0.02697

3.551 - 0.954 - 0.879 0.858 0.860

Mlig455_006534 {REF} {Length: 689} {RNA1509_22927} {RNA1310_81957.1} {RNA815_41771.2}

Mlig455_006538 {REF} {Length: 1691} {RNA1509_12380} {RNA1310_164.2} {RNA815_19957}

Mlig455_006649 {REF} {Length: 829} {RNA1509_22927} {RNA1310_81957.1} {RNA815_41771.2}

Mlig455_006700 {REF} {Length: 750} {RNA1509_22927} {RNA1310_81957.2} {RNA815_41771.2}
7. MligTC455_11473 248 5.17 Mlig455_009711, Mlig455_071036

Neo: -

Age: Down-Up-Down

CHRNA3 3.546 0.973 0.907 0.746 - 0.920 -

Mlig455_009711 {REF} {Length: 2402} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=241.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=222.9]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=391, Expect=2e-130]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=379, Expect=6e-126]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=375, Expect=2e-124]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=390, Expect=2e-130]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=375, Expect=2e-124]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [RH, Score=499, Expect=9e-173]} {Celegans: WBGene00000043, acr-3, Acetylcholine receptor subunit beta-type acr-3, [RH, Score=426, Expect=6e-145]} {Smed: dd_Smed_v6_12146_0_1, dd_Smed_v6_12146_0_1, [Score=510, Expect=1e-176]} {RNA1509_48201} {RNA1310_10118} {RNA815_29940}

Mlig455_071036 {REF} {Length: 746} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=28.1]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [Score=63.5, Expect=2e-13]} {Celegans: WBGene00000042, acr-2, Acetylcholine receptor subunit beta-type acr-2, [Score=63.9, Expect=9e-14]} {Smed: dd_Smed_v6_12535_0_1, dd_Smed_v6_12535_0_1, [Score=64.3, Expect=6e-14]} {RNA1310_21182} {RNA815_29940}
8. MligTC455_44354 1240 25.82 Mlig455_001577

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.349

Region-specific R2: 5.143

Region-enriched R2: 4.498/0.00000

Regeneration-downregulated R2: -2.807

Regeneration-depleted R2: -2.807

3.533 - 0.911 - 0.906 0.746 0.970 Mlig455_001577 {REF} {Length: 1028} {RNA1509_23470, RNA1509_33941, RNA1509_57202} {RNA1310_49541.2, RNA1509_23470, RNA1509_33941, RNA1509_57202} {RNA1509_23470, RNA1509_33941, RNA1509_57202, RNA815_59782}
9. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

3.486 0.937 0.878 - - 0.953 0.718 Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
10. MligTC455_44904 1501 31.27 Mlig455_021814

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.865

Region-enriched R2: 3.792/0.00000

3.468 - 0.773 - 0.961 0.848 0.886 Mlig455_021814 {REF} {Length: 959} {RNA1509_15805} {RNA1310_67099.1, RNA1509_15805} {RNA1509_15805, RNA815_17533}
11. MligTC455_26765 686 14.29 Mlig455_006971

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.201/0.00046

3.465 0.921 0.874 - - 0.951 0.719 Mlig455_006971 {REF} {Length: 6360} {Pfam: Cadherin domain [PF00028.19, score=29.2]} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [RH, Score=328, Expect=1e-93]} {RNA1509_19813, RNA1509_5311} {RNA1310_621, RNA1509_19813, RNA1509_5311} {RNA1509_19813, RNA1509_5311, RNA815_183.1}
12. MligTC455_16334 23 0.47 Mlig455_048897

Neo: -

Age: -

GABBR2 3.454 - - 0.808 0.854 0.830 0.962 Mlig455_048897 {REF} {Length: 2632} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=156.6]; Receptor family ligand binding region [PF01094.30, score=109.3]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=307, Expect=2e-91]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=306, Expect=2e-91]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=267, Expect=5e-76]} {Celegans: WBGene00021528, gbb-1, GABA B receptor subunit; GABAB1 receptor subunit, [Score=234, Expect=4e-66]} {Smed: dd_Smed_v6_51663_0_1, dd_Smed_v6_51663_0_1, [Score=129, Expect=2e-33]} {RNA1509_38426} {RNA1310_30172} {RNA815_43578}
13. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 3.43 0.979 - - 0.849 0.876 0.726 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
14. MligTC455_33287 444 9.24 Mlig455_061811

Neo: -

Age: -

Region-enriched R2: 4.031/0.00004

3.409 0.717 0.871 - 0.954 - 0.867 Mlig455_061811 {REF} {Length: 782} {RNA1509_48963} {RNA1310_53012} {RNA815_23468}
15. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 3.386 - 0.928 - 0.783 0.965 0.710

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
16. MligTC455_19819 67 1.39 Mlig455_042327, Mlig455_047107

Neo: -

Age: -

3.372 - - 0.749 0.965 0.786 0.872

Mlig455_042327 {REF} {Length: 1414} {RNA1310_83687}

Mlig455_047107 {REF} {Length: 1283} {RNA1310_83687}
17. MligTC455_46924 1562 32.53 Mlig455_042561

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.240

Region-enriched R2: 5.226/0.00021
Region-enriched R3: 3.273/0.00853

PI16 3.327 - 0.814 - 0.975 0.765 0.773 Mlig455_042561 {REF} {Length: 1929} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=59.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=75.5, Expect=4e-14]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=78.6, Expect=3e-15]; ENSMUSG00000020213, Glipr1l1, GLI pathogenesis-related 1 like 1, [Score=75.1, Expect=5e-15]} {Dmel: FBgn0038126, CG8483, [Score=65.9, Expect=2e-11]} {Celegans: WBGene00003055, lon-1, LONg, [Score=65.9, Expect=7e-12]} {Smed: dd_Smed_v6_2021_0_1, dd_Smed_v6_2021_0_1, [RH, Score=140, Expect=2e-36]} {RNA1509_33691, RNA1509_4403} {RNA1310_19427.1, RNA1509_33691, RNA1509_4403} {RNA1509_33691, RNA1509_4403, RNA815_7689.1}
18. MligTC455_19449 235 4.9 Mlig455_048896

Neo: -

Age: logFC(26M/2M)=-0.470

Region-enriched R2: 3.185/0.00006

3.324 - - 0.710 0.951 0.823 0.840 Mlig455_048896 {REF} {Length: 1819} {Pfam: Innexin [PF00876.20, score=25.6]} {RNA1509_47060} {RNA1310_19756.1, RNA1509_47060} {RNA1509_47060, RNA815_16217}
19. MligTC455_46009 5464 113.82 Mlig455_061251, Mlig455_062639

Neo: -

Age: logFC(26M/2M)=-0.276

Region-specific R2: 2.871

Region-enriched R2: 2.103/0.00001

3.271 0.705 0.869 - 0.964 0.733 -

Mlig455_061251 {REF} {Length: 1343} {Smed: dd_Smed_v6_1520_0_1, dd_Smed_v6_1520_0_1, [Score=54.7, Expect=6e-10]} {RNA1509_3086} {RNA1310_72677.2} {RNA815_25863}

Mlig455_062639 {REF} {Length: 1176} {Smed: dd_Smed_v6_1520_0_1, dd_Smed_v6_1520_0_1, [Score=54.7, Expect=6e-10]} {RNA1509_3086} {RNA1310_72677.2} {RNA815_25863}
20. MligTC455_42338 421 8.78 Mlig455_024562

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.340

FAT4 3.091 0.703 - - 0.710 0.957 0.721 Mlig455_024562 {REF} {Length: 12637} {Pfam: Cadherin domain [PF00028.19, score=1008.3]; Cadherin-like [PF16184.7, score=73.0]; Cadherin-like [PF08266.14, score=52.4]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=722, Expect=0.0]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=751, Expect=0.0]} {Dmel: FBgn0001075, ft, fat, [Score=598, Expect=8e-171]} {Celegans: WBGene00000396, cdh-4, Cadherin-4, [Score=417, Expect=3e-116]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=258, Expect=3e-68]} {RNA1509_28373} {RNA1310_175} {RNA815_9428}
21. MligTC455_47704 106 2.21 Mlig455_032247

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.432

WSCD2 2.804 - - - 0.929 0.913 0.962 Mlig455_032247 {REF} {Length: 2305} {Pfam: WSC domain [PF01822.21, score=58.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=54.7, Expect=1e-07]; ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.8, Expect=5e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=56.6, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-10]} {RNA1509_59284} {RNA1310_13567} {RNA815_27780}
22. MligTC455_36950 42 0.88 Mlig455_022867

Neo: -

Age: -

KIAA1217 2.75 - - - 0.855 0.991 0.904 Mlig455_022867 {REF} {Length: 3173} {Human: ENSG00000120549, KIAA1217, KIAA1217, [RH, Score=72.4, Expect=3e-12]} {Mouse: ENSMUSG00000036617, Etl4, enhancer trap locus 4, [RH, Score=65.9, Expect=2e-10]} {Dmel: FBgn0023531, CG32809, [Score=70.9, Expect=4e-12]} {Celegans: WBGene00022180, Y71H2AM.15, [RH, Score=62.0, Expect=1e-09]} {RNA1310_85458} {RNA815_59686}
23. MligTC455_52549 150 3.12 Mlig455_002138, Mlig455_002284

Neo: -

Age: -

Regeneration-depleted BL: -6.786
Regeneration-depleted TP: -4.939

2.736 - - - 0.891 0.954 0.891

Mlig455_002138 {REF} {Length: 4372} {Pfam: Innexin [PF00876.20, score=62.4]} {Smed: dd_Smed_v6_9861_0_1, dd_Smed_v6_9861_0_1, [Score=60.1, Expect=9e-10]} {RNA1509_36214} {RNA1310_17023} {RNA815_33132}

Mlig455_002284 {REF} {Length: 2783} {Pfam: Innexin [PF00876.20, score=63.0]} {Smed: dd_Smed_v6_9861_0_1, dd_Smed_v6_9861_0_1, [Score=61.2, Expect=4e-10]} {RNA1509_36214} {RNA1310_17023} {RNA815_33132}
24. MligTC455_45191 1420 29.58 Mlig455_000192, Mlig455_058450, Mlig455_067701

Neo: -

Age: -

Regeneration-downregulated BL: -2.403

Regeneration-depleted BL: -2.403

BSG 2.728 - 0.890 - 0.866 0.972 -

Mlig455_000192 {REF} {Length: 2540} {Pfam: Immunoglobulin domain [PF13927.8, score=57.1]; Immunoglobulin I-set domain [PF07679.18, score=53.6]; Immunoglobulin domain [PF00047.27, score=36.0]; Immunoglobulin domain [PF13895.8, score=30.4]; Immunoglobulin V-set domain [PF07686.19, score=22.2]} {Human: ENSG00000172270, BSG, basigin (Ok blood group), [Score=67.8, Expect=1e-12]} {Mouse: ENSMUSG00000023175, Bsg, basigin, [Score=82.4, Expect=3e-17]} {Dmel: FBgn0261822, Bsg, Basigin, [RH, Score=61.6, Expect=1e-10]} {Celegans: WBGene00004729, sax-3, [Score=57.4, Expect=6e-09]} {Smed: dd_Smed_v6_1827_0_1, dd_Smed_v6_1827_0_1, [Score=81.6, Expect=9e-18]} {RNA1509_31454, RNA1509_47270} {RNA1310_8812, RNA1509_31454, RNA1509_47270} {RNA1509_31454, RNA1509_47270, RNA815_2422}

Mlig455_058450 {REF} {Length: 3207} {Pfam: Immunoglobulin domain [PF13927.8, score=56.4]; Immunoglobulin I-set domain [PF07679.18, score=53.0]; Immunoglobulin domain [PF00047.27, score=36.1]; Immunoglobulin domain [PF13895.8, score=29.3]; Immunoglobulin V-set domain [PF07686.19, score=22.0]} {Human: ENSG00000172270, BSG, basigin (Ok blood group), [Score=67.4, Expect=2e-12]} {Mouse: ENSMUSG00000023175, Bsg, basigin, [Score=81.6, Expect=6e-17]} {Dmel: FBgn0261822, Bsg, Basigin, [RH, Score=62.4, Expect=6e-11]} {Celegans: WBGene00004729, sax-3, [Score=58.5, Expect=3e-09]} {Smed: dd_Smed_v6_1827_0_1, dd_Smed_v6_1827_0_1, [Score=80.5, Expect=3e-17]} {RNA1509_31454} {RNA1310_8812} {RNA815_2422}

Mlig455_067701 {REF} {Length: 2864} {Celegans: WBGene00018026, F35A5.4, [Score=60.1, Expect=8e-11]} {RNA1509_47270} {RNA1310_8812} {RNA815_2422}
25. MligTC455_53579 15576 324.49 Mlig455_010515

Neo: -

Age: -

Region-enriched R2: 1.446/0.00265

Regeneration-downregulated BL: -1.566

Regeneration-depleted BL: -1.566

2.711 - 0.904 - 0.824 0.983 - Mlig455_010515 {REF} {Length: 1448} {Pfam: Neuroendocrine protein 7B2 precursor (Secretogranin V) [PF05281.13, score=80.3]} {Dmel: FBgn0041707, 7B2, [RH, Score=70.1, Expect=2e-13]} {Celegans: WBGene00011392, sbt-1, Seven B Two (Mammalian 7BT prohormone convertase chaperone) homolog, [RH, Score=67.4, Expect=5e-13]} {Smed: dd_Smed_v6_3862_0_1, dd_Smed_v6_3862_0_1, [RH, Score=119, Expect=7e-32]} {RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1310_24594, RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1509_1202, RNA1509_1348, RNA1509_17830, RNA815_8289}
26. MligTC455_18539 1250 26.03 Mlig455_003030

Neo: -

Age: logFC(26M/2M)=-0.308

Region-specific R2: 5.210

Region-enriched R2: 4.715/0.00000
Region-enriched R3: 3.959/0.00000

SFRP2 2.704 - - - 0.971 0.882 0.851 Mlig455_003030 {REF} {Length: 2108} {Pfam: Fz domain [PF01392.24, score=88.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=166, Expect=7e-48]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-47]; ENSMUSG00000031548, Sfrp1, secreted frizzled-related protein 1, [RH, Score=157, Expect=2e-44]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=2e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=6e-47]} {Smed: dd_Smed_v6_8832_0_1, dd_Smed_v6_8832_0_1, [RH, Score=153, Expect=4e-43]} {RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1310_15264, RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1509_32854, RNA1509_44148, RNA1509_5709, RNA815_7067}
27. MligTC455_18540 1213 25.28 Mlig455_003235

Neo: -

Age: -

Region-specific R2: 5.238

Region-enriched R2: 4.787/0.00000
Region-enriched R3: 3.982/0.00000

SFRP2 2.703 - - - 0.973 0.873 0.857 Mlig455_003235 {REF} {Length: 1691} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=86.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=167, Expect=4e-46]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-45]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=101, Expect=8e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=1e-44]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=157, Expect=1e-42]} {RNA1509_5709} {RNA1310_15264} {RNA815_7067}
28. MligTC455_21668 84 1.74 Mlig455_024837

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.324

PPP3R1 2.696 - - - 0.962 0.823 0.911 Mlig455_024837 {REF} {Length: 1650} {Pfam: EF hand [PF00036.34, score=92.6]; EF-hand domain pair [PF13499.8, score=86.6]; EF-hand domain [PF13405.8, score=74.3]; EF hand [PF13202.8, score=72.6]; EF-hand domain pair [PF13833.8, score=65.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.0]; EF-hand domain [PF14658.8, score=21.7]} {Human: ENSG00000221823, PPP3R1, protein phosphatase 3 regulatory subunit B, alpha, [RH, Score=289, Expect=5e-101]} {Mouse: ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [RH, Score=289, Expect=3e-101]} {Dmel: FBgn0010014, CanB, Calcineurin B, [RH, Score=282, Expect=1e-98]} {Celegans: WBGene00000554, cnb-1, Protein phosphatase 2B regulatory subunit cnb-1, [RH, Score=272, Expect=7e-95]} {Smed: dd_Smed_v6_5589_0_1, dd_Smed_v6_5589_0_1, [RH, Score=281, Expect=1e-98]} {RNA1509_14613} {RNA1310_16848.1} {RNA815_6272}
29. MligTC455_31695 158 3.3 Mlig455_009775

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.086/0.01194

2.695 - - - 0.977 0.958 0.760 Mlig455_009775 {REF} {Length: 2186} {RNA1310_24838} {RNA815_18727}
30. MligTC455_50927 254 5.29 Mlig455_070541, Mlig455_070562

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.296

Region-enriched R2: 7.883/0.00008
Region-enriched R3: 4.441/0.03979

FZD4 2.685 - - - 0.964 0.933 0.788

Mlig455_070541 {REF} {Length: 3522} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=471, Expect=6e-159]} {RNA1509_15834} {RNA1310_3800, RNA1509_15834} {RNA1509_15834, RNA815_19571}

Mlig455_070562 {REF} {Length: 3527} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=2e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=470, Expect=8e-159]} {RNA1509_15834} {RNA1310_3800} {RNA815_19571}
31. MligTC455_40648 60 1.24 Mlig455_034479

Neo: -

Age: Down-Up-Up

2.676 - - - 0.942 0.767 0.967 Mlig455_034479 {REF} {Length: 2499} {RNA1310_42980.1} {RNA815_47590}
32. MligTC455_53413 249 5.2 Mlig455_035022

Neo: -

Age: -

Region-specific R2: 4.451

Region-enriched R2: 3.023/0.00460

RP1 2.665 - - - 0.950 0.884 0.831 Mlig455_035022 {REF} {Length: 5065} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_57003} {RNA1310_2710} {RNA815_13802.1}
33. MligTC455_14829 56 1.17 Mlig455_053237

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.599

Region-enriched R2: 3.828/0.03404

SSUH2 2.658 - - 0.810 - 0.889 0.959 Mlig455_053237 {REF} {Length: 1420} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=156, Expect=2e-43]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=117, Expect=2e-29]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=87.4, Expect=9e-19]} {RNA1509_46058} {RNA1310_5028.1} {RNA815_5650}
34. MligTC455_13503 70 1.46 Mlig455_010582, Mlig455_010601

Neo: -

Age: -

TRHR 2.657 - - - 0.797 0.989 0.871

Mlig455_010582 {REF} {Length: 2404} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=41.0]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=53.1, Expect=4e-07]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=57.8, Expect=1e-08]} {Dmel: FBgn0029723, Proc-R, Proctolin receptor, [Score=66.2, Expect=2e-11]} {Celegans: WBGene00016265, trhr-1, Thyrotropin-Releasing Hormone Receptor, [Score=55.1, Expect=4e-08]} {Smed: dd_Smed_v6_25364_0_1, dd_Smed_v6_25364_0_1, [Score=167, Expect=2e-47]} {RNA1310_120532}

Mlig455_010601 {REF} {Length: 2481} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=52.6]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=56.2, Expect=5e-08]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=57.0, Expect=2e-08]; ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=57.0, Expect=2e-08]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=74.3, Expect=6e-14]} {Celegans: WBGene00020069, R13H7.2, [Score=54.7, Expect=6e-08]} {Smed: dd_Smed_v6_13560_0_1, dd_Smed_v6_13560_0_1, [RH, Score=177, Expect=3e-51]} {RNA1310_92274}
35. MligTC455_37989 83 1.72 Mlig455_018192

Neo: -

Age: -

2.656 0.971 - - 0.860 0.825 - Mlig455_018192 {REF} {Length: 1275} {Pfam: EF-hand domain pair [PF13499.8, score=36.8]; EF-hand domain [PF13405.8, score=31.2]; EF hand [PF00036.34, score=29.3]; EF-hand domain pair [PF13833.8, score=20.5]; EF hand [PF13202.8, score=19.4]} {Smed: dd_Smed_v6_1010_0_1, dd_Smed_v6_1010_0_1, [Score=105, Expect=6e-27]} {RNA1310_31713.1} {RNA815_36423}
36. MligTC455_38698 945 19.68 Mlig455_009780

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.658

Region-enriched R2: 1.739/0.00137

Regeneration-downregulated BL: -2.534

Regeneration-depleted BL: -2.534

COLEC10 2.641 0.889 - - 0.966 0.786 - Mlig455_009780 {REF} {Length: 1506} {Pfam: Lectin C-type domain [PF00059.23, score=43.5]} {Human: ENSG00000184374, COLEC10, collectin subfamily member 10, [Score=50.4, Expect=2e-07]} {Mouse: ENSMUSG00000038591, Colec10, collectin sub-family member 10, [Score=47.8, Expect=1e-06]} {RNA1509_22697} {RNA1310_23822} {RNA815_11460}
37. MligTC455_45080 3677 76.61 Mlig455_021478, Mlig455_062024, Mlig455_063226, Mlig455_067363

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.291

Region-enriched R8: 1.930/0.00003

2.635 - 0.799 - 0.983 0.853 -

Mlig455_021478 {REF} {Length: 753} {RNA1509_11225} {RNA1310_43601} {RNA815_21702}

Mlig455_062024 {REF} {Length: 752} {RNA1509_11225} {RNA1310_43601} {RNA815_21702}

Mlig455_063226 {REF} {Length: 753} {RNA1509_11225} {RNA1310_43601} {RNA815_21702}

Mlig455_067363 {REF} {Length: 767} {RNA1509_11225} {RNA1310_43601} {RNA815_21702}
38. MligTC455_15189 30 0.63 Mlig455_068662

Neo: -

Age: -

2.626 - - 0.739 - 0.980 0.907 Mlig455_068662 {REF} {Length: 1194} {Pfam: Cupin-like domain [PF13621.8, score=39.8]} {Dmel: FBgn0038510, CG14331, [Score=148, Expect=1e-41]} {Celegans: WBGene00004205, psr-1, Bifunctional arginine demethylase and lysyl-hydroxylase psr-1, [Score=49.7, Expect=1e-06]} {Smed: dd_Smed_v6_8235_0_1, dd_Smed_v6_8235_0_1, [Score=139, Expect=5e-38]} {RNA1509_3781} {RNA1310_5604.1} {RNA815_2493.1}
39. MligTC455_16866 18 0.37 Mlig455_065296

Neo: -

Age: -

2.625 - - 0.700 0.981 0.944 - Mlig455_065296 {REF} {Length: 1827} {RNA1310_92472}
40. MligTC455_16867 18 0.37 Mlig455_065319

Neo: -

Age: -

2.625 - - 0.700 0.981 0.944 - Mlig455_065319 {REF} {Length: 1743} {RNA1310_92472}
41. MligTC455_21182 238 4.96 Mlig455_000068, Mlig455_063733

Neo: -

Age: Down-Up-Up

Region-enriched R4: 5.301/0.04587

2.617 - 0.765 - 0.957 - 0.895

Mlig455_000068 {REF} {Length: 468} {Pfam: Pancreatic hormone peptide [PF00159.20, score=23.7]} {RNA1310_81800.1} {RNA815_55075}

Mlig455_063733 {REF} {Length: 531} {Pfam: Pancreatic hormone peptide [PF00159.20, score=20.7]} {RNA1310_81800.1} {RNA815_55075}
42. MligTC455_48603 1006 20.95 Mlig455_058556

Neo: -

Age: -

Region-enriched R2: 1.380/0.01205

Regeneration-downregulated BL: -2.368

Regeneration-depleted BL: -2.368

CALM2 2.594 0.703 - - 0.935 0.956 - Mlig455_058556 {REF} {Length: 2727} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=101.0]; EF hand [PF00036.34, score=97.2]; EF-hand domain pair [PF13833.8, score=81.7]; EF-hand domain [PF13405.8, score=78.5]; EF hand [PF13202.8, score=71.6]; EF-hand domain [PF14658.8, score=41.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=31.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.3]; Dockerin type I domain [PF00404.20, score=25.5]; SurA N-terminal domain [PF13624.8, score=19.1]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=132, Expect=1e-37]; ENSG00000160014, CALM3, calmodulin 3, [Score=130, Expect=5e-37]; ENSG00000198668, CALM1, calmodulin 1, [Score=130, Expect=3e-37]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=135, Expect=8e-39]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=130, Expect=3e-37]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=130, Expect=3e-37]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=127, Expect=3e-36]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=127, Expect=2e-36]} {Smed: dd_Smed_v6_12048_0_2, dd_Smed_v6_12048_0_2, [RH, Score=163, Expect=8e-49]} {RNA1509_36324, RNA1509_52694, RNA1509_5720} {RNA1310_6210.2, RNA1509_36324, RNA1509_52694, RNA1509_5720} {RNA1509_36324, RNA1509_52694, RNA1509_5720, RNA815_4293.1}
43. MligTC455_19040 49 1.03 Mlig455_003437

Neo: -

Age: -

Region-enriched R2: 6.133/0.00615
Region-enriched R3: 4.021/0.03085

CAV1 2.591 - 0.855 - 0.767 0.969 - Mlig455_003437 {REF} {Length: 808} {Pfam: Caveolin [PF01146.19, score=118.3]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=101, Expect=7e-28]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=102, Expect=2e-28]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.6, Expect=9e-17]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=142, Expect=8e-45]} {RNA1509_53381} {RNA1310_97043} {RNA815_32565}
44. MligTC455_48792 145 3.02 Mlig455_049885

Neo: -

Age: -

2.587 - - 0.848 0.953 - 0.786 Mlig455_049885 {REF} {Length: 1335} {RNA1509_59166} {RNA1310_26794.2} {RNA815_13204}
45. MligTC455_13905 34 0.71 Mlig455_023395

Neo: -

Age: -

2.567 0.966 - - - 0.769 0.832 Mlig455_023395 {REF} {Length: 1110} {Smed: dd_Smed_v6_12856_0_1, dd_Smed_v6_12856_0_1, [Score=47.0, Expect=2e-06]} {RNA1509_18233} {RNA1310_51675} {RNA815_25040}
46. MligTC455_51478 66 1.37 Mlig455_057080

Neo: -

Age: -

2.564 - - - 0.843 0.978 0.743 Mlig455_057080 {REF} {Length: 1661} {Pfam: 7tm Chemosensory receptor [PF08395.14, score=33.2]; Trehalose receptor [PF06151.15, score=30.3]} {RNA1310_59684} {RNA815_43381}
47. MligTC455_48757 61 1.28 Mlig455_008828, Mlig455_008932

Neo: -

Age: Up-Down-Up

DDC 2.563 - 0.760 - 0.978 0.825 -

Mlig455_008828 {REF} {Length: 2057} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=471.9]} {Human: ENSG00000132437, DDC, dopa decarboxylase, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000020182, Ddc, dopa decarboxylase, [RH, Score=558, Expect=0.0]} {Dmel: FBgn0000422, Ddc, Dopa decarboxylase, [RH, Score=553, Expect=0.0]} {Celegans: WBGene00006562, tdc-1, Tyrosine decarboxylase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_11320_0_1, dd_Smed_v6_11320_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_37174} {RNA815_42090}

Mlig455_008932 {REF} {Length: 2145} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=470.1]} {Human: ENSG00000132437, DDC, dopa decarboxylase, [RH, Score=574, Expect=0.0]} {Mouse: ENSMUSG00000020182, Ddc, dopa decarboxylase, [RH, Score=559, Expect=0.0]} {Dmel: FBgn0000422, Ddc, Dopa decarboxylase, [RH, Score=554, Expect=0.0]} {Celegans: WBGene00006562, tdc-1, Tyrosine decarboxylase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_11320_0_1, dd_Smed_v6_11320_0_1, [RH, Score=564, Expect=0.0]} {RNA1310_37174} {RNA815_42090}
48. MligTC455_38838 24 0.49 Mlig455_033571, Mlig455_067059

Neo: -

Age: -

2.562 - - 0.738 0.957 0.867 -

Mlig455_033571 {REF} {Length: 1596} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=62.5]; Capsular polysaccharide synthesis protein [PF05704.14, score=18.7]} {Smed: dd_Smed_v6_42389_0_1, dd_Smed_v6_42389_0_1, [RH, Score=144, Expect=1e-39]} {RNA1310_19511} {RNA815_7578}

Mlig455_067059 {REF} {Length: 1559} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=62.5]; Capsular polysaccharide synthesis protein [PF05704.14, score=18.7]} {Smed: dd_Smed_v6_42389_0_1, dd_Smed_v6_42389_0_1, [RH, Score=144, Expect=1e-39]} {RNA1310_19511} {RNA815_7578}
49. MligTC455_48609 3538 73.7 Mlig455_037431, Mlig455_037454, Mlig455_037501

Neo: -

Age: -

Region-specific R2: 3.134

Region-enriched R2: 1.985/0.00000

Regeneration-downregulated BL: -2.003

Regeneration-depleted BL: -2.003

CAPN5 2.556 - 0.955 - - 0.899 0.702

Mlig455_037431 {REF} {Length: 2455} {Pfam: Calpain family cysteine protease [PF00648.23, score=124.0]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=103, Expect=1e-22]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=2e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=103, Expect=5e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}

Mlig455_037454 {REF} {Length: 1043} {RNA1509_15549} {RNA1310_57168} {RNA815_30048}

Mlig455_037501 {REF} {Length: 2687} {Pfam: Calpain family cysteine protease [PF00648.23, score=123.7]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=105, Expect=5e-23]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=3e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=104, Expect=4e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}
50. MligTC455_17039 24 0.5 Mlig455_025016

Neo: -

Age: -

2.549 - - 0.778 0.983 0.788 - Mlig455_025016 {REF} {Length: 2009} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=72.7]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.5]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=18.8]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [RH, Score=209, Expect=1e-63]} {RNA1310_42205} {RNA815_15017}
51. MligTC455_49557 280 5.82 Mlig455_017273

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.728

Region-specific R2: 3.642

Region-enriched R2: 3.187/0.00196

2.543 0.971 - - 0.784 0.788 - Mlig455_017273 {REF} {Length: 1333} {RNA1509_52848} {RNA1310_64923, RNA1509_52848} {RNA1509_52848, RNA815_51063}
52. MligTC455_46155 116 2.42 Mlig455_027239

Neo: -

Age: -

Region-enriched R2: 4.163/0.03818

GRK3 2.543 - - - 0.967 0.845 0.731 Mlig455_027239 {REF} {Length: 2919} {Pfam: Protein kinase domain [PF00069.27, score=226.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=100.5]; Regulator of G protein signaling domain [PF00615.21, score=48.3]} {Human: ENSG00000100077, GRK3, G protein-coupled receptor kinase 3, [Score=845, Expect=0.0]; ENSG00000173020, GRK2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Mouse: ENSMUSG00000042249, Grk3, G protein-coupled receptor kinase 3, [Score=838, Expect=0.0]; ENSMUSG00000024858, Grk2, G protein-coupled receptor kinase 2, [Score=838, Expect=0.0]} {Dmel: FBgn0260798, Gprk1, G protein-coupled receptor kinase 1, [Score=842, Expect=0.0]} {Celegans: WBGene00001709, grk-2, G protein-coupled receptor kinase 2, [Score=819, Expect=0.0]} {Smed: dd_Smed_v6_6480_0_1, dd_Smed_v6_6480_0_1, [Score=949, Expect=0.0]} {RNA1509_7002} {RNA1310_16658} {RNA815_28070}
53. MligTC455_03228 275 5.73 Mlig455_035802

Neo: -

Age: -

Region-enriched R2: 2.387/0.02287

KCNN2 2.534 - 0.746 - 0.821 0.967 - Mlig455_035802 {REF} {Length: 3854} {Pfam: Calcium-activated SK potassium channel [PF03530.16, score=141.7]; Calmodulin binding domain [PF02888.18, score=74.3]; Ion channel [PF07885.18, score=58.4]} {Human: ENSG00000080709, KCNN2, potassium calcium-activated channel subfamily N member 2, [Score=398, Expect=1e-133]; ENSG00000143603, KCNN3, potassium calcium-activated channel subfamily N member 3, [Score=396, Expect=8e-131]; ENSG00000105642, KCNN1, potassium calcium-activated channel subfamily N member 1, [Score=395, Expect=9e-133]} {Mouse: ENSMUSG00000054477, Kcnn2, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, [Score=399, Expect=6e-131]; ENSMUSG00000000794, Kcnn3, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3, [Score=397, Expect=2e-131]; ENSMUSG00000002908, Kcnn1, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, [Score=387, Expect=4e-130]; ENSMUSG00000111706, Kcnn1, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, [Score=387, Expect=4e-130]} {Dmel: FBgn0029761, SK, small conductance calcium-activated potassium channel, [Score=422, Expect=5e-144]} {Celegans: WBGene00008570, kcnl-2, KCNL-2 variant; KCNN (Potassium K ChaNNel, calcium activated)-Like, [Score=333, Expect=5e-108]} {Smed: dd_Smed_v6_13309_0_1, dd_Smed_v6_13309_0_1, [RH, Score=481, Expect=6e-168]} {RNA1509_42110} {RNA1310_18606.1, RNA1509_42110} {RNA1509_42110, RNA815_13732}
54. MligTC455_03227 266 5.54 Mlig455_035719

Neo: -

Age: -

Region-enriched R2: 2.342/0.02665

2.533 - 0.746 - 0.821 0.966 - Mlig455_035719 {REF} {Length: 154} {NoTransDecoderORF} {RNA1310_97182} {RNA815_18537}
55. MligTC455_35019 168 3.49 Mlig455_046994

Neo: -

Age: -

ASIC4 2.528 - - - 0.850 0.955 0.723 Mlig455_046994 {REF} {Length: 4001} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.4]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=76.3, Expect=8e-14]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=72.8, Expect=8e-13]} {Smed: dd_Smed_v6_15233_0_1, dd_Smed_v6_15233_0_1, [RH, Score=103, Expect=1e-22]} {RNA1509_33816} {RNA1310_3176, RNA1509_33816} {RNA1509_33816, RNA815_12439}
56. MligTC455_21719 441 9.18 Mlig455_025497, Mlig455_025520, Mlig455_070509

Neo: -

Age: -

SLC6A1 2.522 - 0.717 - 0.960 0.845 -

Mlig455_025497 {REF} {Length: 3353} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=655.7]} {Human: ENSG00000157103, SLC6A1, solute carrier family 6 member 1, [RH, Score=592, Expect=0.0]} {Mouse: ENSMUSG00000030310, Slc6a1, solute carrier family 6 (neurotransmitter transporter, GABA), member 1, [RH, Score=592, Expect=0.0]} {Dmel: FBgn0039915, Gat, GABA transporter, [RH, Score=590, Expect=0.0]} {Celegans: WBGene00004910, snf-11, Transporter, [RH, Score=599, Expect=0.0]} {Smed: dd_Smed_v6_8169_0_1, dd_Smed_v6_8169_0_1, [RH, Score=652, Expect=0.0]} {RNA1509_27603} {RNA1310_5653.1} {RNA815_1806}

Mlig455_025520 {REF} {Length: 3631} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=655.7]} {Human: ENSG00000157103, SLC6A1, solute carrier family 6 member 1, [RH, Score=592, Expect=0.0]} {Mouse: ENSMUSG00000030310, Slc6a1, solute carrier family 6 (neurotransmitter transporter, GABA), member 1, [RH, Score=592, Expect=0.0]} {Dmel: FBgn0039915, Gat, GABA transporter, [RH, Score=590, Expect=0.0]} {Celegans: WBGene00004910, snf-11, Transporter, [RH, Score=599, Expect=0.0]} {Smed: dd_Smed_v6_8169_0_1, dd_Smed_v6_8169_0_1, [RH, Score=652, Expect=0.0]} {RNA1509_27603} {RNA1310_5653.1, RNA1509_27603} {RNA1509_27603, RNA815_1806}

Mlig455_070509 {REF} {Length: 3425} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=631.8]} {Human: ENSG00000157103, SLC6A1, solute carrier family 6 member 1, [RH, Score=576, Expect=0.0]} {Mouse: ENSMUSG00000030310, Slc6a1, solute carrier family 6 (neurotransmitter transporter, GABA), member 1, [RH, Score=577, Expect=0.0]} {Dmel: FBgn0039915, Gat, GABA transporter, [RH, Score=575, Expect=0.0]} {Celegans: WBGene00004910, snf-11, Transporter, [RH, Score=583, Expect=0.0]} {Smed: dd_Smed_v6_8169_0_1, dd_Smed_v6_8169_0_1, [RH, Score=636, Expect=0.0]} {RNA1509_27603} {RNA1310_5653.1} {RNA815_1806}
57. MligTC455_29725 72 1.49 Mlig455_014390

Neo: -

Age: -

Region-enriched R2: 7.905/0.00012

OTOP2 2.504 - - 0.772 0.967 0.765 - Mlig455_014390 {REF} {Length: 2547} {Pfam: Otopetrin [PF03189.15, score=220.6]} {Human: ENSG00000183034, OTOP2, otopetrin 2, [Score=52.0, Expect=3e-06]; ENSG00000163982, OTOP1, otopetrin 1, [Score=49.7, Expect=1e-05]} {Mouse: ENSMUSG00000051596, Otop1, otopetrin 1, [Score=53.5, Expect=7e-07]; ENSMUSG00000050201, Otop2, otopetrin 2, [Score=51.6, Expect=3e-06]} {Dmel: FBgn0259150, CG42265, [Score=177, Expect=3e-46]} {Celegans: WBGene00017034, otpl-2, OToPetrin-Like, [Score=101, Expect=2e-22]} {Smed: dd_Smed_v6_13612_0_3, dd_Smed_v6_13612_0_3, [Score=276, Expect=7e-84]} {RNA1310_55206} {RNA815_48323}
58. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

ANGPTL3 2.502 - - - 0.751 0.975 0.776 Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
59. MligTC455_47779 196 4.09 Mlig455_018651

Neo: -

Age: Down-Down-Up

Region-enriched R2: 5.953/0.04766
Region-enriched R3: 5.735/0.00160

2.487 - 0.795 0.739 0.953 - - Mlig455_018651 {REF} {Length: 521} {RNA1509_48336} {RNA1310_73351} {RNA815_41082}
60. MligTC455_20114 4655 96.97 Mlig455_032750

Neo: -

Age: -

Region-enriched R2: 6.812/0.00000
Region-enriched R3: 5.878/0.00000

ADAMTS7 2.482 - - - 0.965 0.808 0.709 Mlig455_032750 {REF} {Length: 1794} {Pfam: Metallo-peptidase family M12 [PF13688.8, score=51.5]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=44.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=39.8]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=37.0]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=26.8]; ADAM cysteine-rich domain [PF17771.3, score=26.3]; Astacin (Peptidase family M12A) [PF01400.26, score=18.3]} {Human: ENSG00000136378, ADAMTS7, ADAM metallopeptidase with thrombospondin type 1 motif 7, [Score=72.4, Expect=1e-12]; ENSG00000134917, ADAMTS8, ADAM metallopeptidase with thrombospondin type 1 motif 8, [Score=72.0, Expect=1e-12]} {Mouse: ENSMUSG00000058145, Adamts17, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17, [Score=70.5, Expect=3e-12]; ENSMUSG00000031994, Adamts8, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8, [Score=70.1, Expect=3e-12]; ENSMUSG00000046169, Adamts6, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6, [Score=69.7, Expect=4e-12]; ENSMUSG00000049538, Adamts16, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16, [Score=68.2, Expect=1e-11]; ENSMUSG00000006403, Adamts4, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, [Score=67.4, Expect=2e-11]} {Dmel: FBgn0029791, CG4096, [Score=74.3, Expect=1e-13]} {Celegans: WBGene00003248, mig-17, ADAM family mig-17, [Score=58.5, Expect=6e-09]} {RNA1509_811} {RNA1310_18102.1, RNA1509_811} {RNA1509_811, RNA815_7066}
61. MligTC455_20113 4626 96.37 Mlig455_032728

Neo: -

Age: -

Region-enriched R2: 7.104/0.00000
Region-enriched R3: 6.207/0.00000

ADAMTS4 2.481 - - - 0.964 0.809 0.708 Mlig455_032728 {REF} {Length: 1834} {Pfam: Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=34.1]; Metallo-peptidase family M12 [PF13688.8, score=30.1]} {Human: ENSG00000158859, ADAMTS4, ADAM metallopeptidase with thrombospondin type 1 motif 4, [Score=50.1, Expect=3e-06]; ENSG00000154734, ADAMTS1, ADAM metallopeptidase with thrombospondin type 1 motif 1, [Score=48.1, Expect=3e-06]} {Mouse: ENSMUSG00000006403, Adamts4, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, [Score=50.1, Expect=2e-06]} {RNA1509_811} {RNA1310_18102.1} {RNA815_7066}
62. MligTC455_46285 568 11.84 Mlig455_063390

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R2: 4.933/0.00026
Region-enriched R3: 3.321/0.00307

2.48 - 0.710 - 0.982 0.788 - Mlig455_063390 {REF} {Length: 871} {RNA1509_48573} {RNA1310_59611, RNA1509_48573} {RNA1509_48573, RNA815_35731}
63. MligTC455_15645 14723 306.72 Mlig455_015733, Mlig455_049437

Neo: -

Age: Down-Down-Up

Region-enriched R7: 1.492/0.00234

Regeneration-downregulated BL: -2.677

Regeneration-depleted BL: -2.677

2.449 - 0.725 - 0.762 0.962 -

Mlig455_015733 {REF} {Length: 960} {Pfam: SLBB domain [PF10531.11, score=20.2]} {RNA1509_3484} {RNA1310_43598.2} {RNA815_17382}

Mlig455_049437 {REF} {Length: 994} {Pfam: YtkA-like [PF13115.8, score=24.2]} {RNA1509_3484} {RNA1310_43598.2} {RNA815_17382}
64. MligTC455_39957 170 3.54 Mlig455_039809

Neo: -

Age: -

Region-specific R2: 4.733

Region-enriched R2: 5.232/0.00000

ADGB 2.441 0.749 - - 0.731 0.961 - Mlig455_039809 {REF} {Length: 7010} {tRNA: Ile(TAT),pseudo, score=33.4} {Pfam: Calpain family cysteine protease [PF00648.23, score=34.1]} {Human: ENSG00000118492, ADGB, androglobin, [Score=403, Expect=6e-115]} {Mouse: ENSMUSG00000050994, Adgb, androglobin, [Score=252, Expect=4e-67]} {Celegans: WBGene00000543, clp-2, CaLPain family, [Score=73.2, Expect=1e-12]} {Smed: dd_Smed_v6_10677_0_1, dd_Smed_v6_10677_0_1, [Score=253, Expect=8e-68]} {RNA1509_15950, RNA1509_59203} {RNA1310_4821, RNA1509_59203} {RNA1509_59203, RNA815_12506}
65. MligTC455_46903 255 5.3 Mlig455_040553

Neo: -

Age: -

Region-enriched R2: 9.597/0.00026

2.438 0.723 - - 0.950 0.765 - Mlig455_040553 {REF} {Length: 562} {RNA1509_45949} {RNA1310_70304, RNA1509_45949} {RNA1509_45949, RNA815_37653}
66. MligTC455_40341 106 2.2 Mlig455_060207, Mlig455_070456

Neo: -

Age: Down-Down-Up

Region-enriched R2: 6.703/0.00648
Region-enriched R3: 4.045/0.03110

NPY2R 2.437 - 0.710 - - 0.753 0.974

Mlig455_060207 {REF} {Length: 3062} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=177.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=47.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=29.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.6]} {Human: ENSG00000185149, NPY2R, neuropeptide Y receptor Y2, [RH, Score=178, Expect=9e-51]} {Mouse: ENSMUSG00000028004, Npy2r, neuropeptide Y receptor Y2, [RH, Score=176, Expect=3e-50]; ENSMUSG00000031932, Gpr83, G protein-coupled receptor 83, [RH, Score=176, Expect=1e-49]} {Dmel: FBgn0036934, sNPF-R, short neuropeptide F receptor, [Score=245, Expect=4e-74]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [RH, Score=215, Expect=5e-65]} {Smed: dd_Smed_v6_15335_0_1, dd_Smed_v6_15335_0_1, [RH, Score=313, Expect=2e-103]} {RNA1310_18147.1} {RNA815_7986}

Mlig455_070456 {REF} {Length: 3569} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=176.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=46.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=29.2]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.3]} {Human: ENSG00000185149, NPY2R, neuropeptide Y receptor Y2, [RH, Score=177, Expect=8e-50]} {Mouse: ENSMUSG00000028004, Npy2r, neuropeptide Y receptor Y2, [RH, Score=175, Expect=3e-49]; ENSMUSG00000031932, Gpr83, G protein-coupled receptor 83, [RH, Score=174, Expect=2e-48]} {Dmel: FBgn0035610, Lkr, Leucokinin receptor, [RH, Score=166, Expect=2e-44]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [Score=215, Expect=4e-64]} {Smed: dd_Smed_v6_15335_0_1, dd_Smed_v6_15335_0_1, [RH, Score=315, Expect=8e-103]} {RNA1310_18147.1} {RNA815_7986}
67. MligTC455_27678 355 7.4 Mlig455_070610

Neo: -

Age: -

Region-specific R2: 4.724

Region-enriched R2: 3.766/0.00062

2.423 - - - 0.963 0.747 0.713 Mlig455_070610 {REF} {Length: 725} {RNA1509_17468, RNA1509_34237} {RNA1310_59474, RNA1509_17468, RNA1509_34237} {RNA1509_17468, RNA1509_34237, RNA815_28024}
68. MligTC455_30540 1159 24.14 Mlig455_048840

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.427

2.416 - 0.736 - - 0.968 0.712 Mlig455_048840 {REF} {Length: 3299} {TRANSSPLICED} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [RH, Score=123, Expect=2e-30]} {RNA1509_3399} {RNA1310_7154.1} {RNA815_2838.1}
69. MligTC455_52727 82 1.72 Mlig455_043336

Neo: -

Age: Down-Up-Down

1.924 - - - 0.943 0.981 - Mlig455_043336 {REF} {Length: 1410} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=60.5]; Capsular polysaccharide synthesis protein [PF05704.14, score=20.9]} {Smed: dd_Smed_v6_6819_0_1, dd_Smed_v6_6819_0_1, [Score=131, Expect=4e-35]} {RNA1509_41314} {RNA1310_26265} {RNA815_9794.1}
70. MligTC455_35773 89 1.86 Mlig455_064449, Mlig455_064456

Neo: -

Age: -

Region-enriched R2: 5.198/0.00725

NANP 1.912 - 0.938 - - 0.974 -

Mlig455_064449 {REF} {Length: 503} {NoTransDecoderORF} {RNA1310_53432.2}

Mlig455_064456 {REF} {Length: 3122} {Pfam: Haloacid dehalogenase-like hydrolase [PF13419.8, score=56.3]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.3]; HAD-hyrolase-like [PF13242.8, score=44.6]} {Human: ENSG00000170191, NANP, N-acetylneuraminic acid phosphatase, [RH, Score=47.4, Expect=8e-06]} {Mouse: ENSMUSG00000053916, Nanp, N-acetylneuraminic acid phosphatase, [RH, Score=48.5, Expect=2e-06]} {Celegans: WBGene00018465, F45E1.4, [RH, Score=147, Expect=4e-43]} {Smed: dd_Smed_v6_2813_0_3, dd_Smed_v6_2813_0_3, [Score=174, Expect=2e-50]} {RNA1310_59243} {RNA815_62364}
71. MligTC455_49020 172 3.58 Mlig455_035624, Mlig455_048255, Mlig455_048315

Neo: -

Age: logFC(26M/2M)=-0.385

Region-enriched R2: 3.728/0.03083

SLC26A5 1.912 0.978 - - 0.934 - -

Mlig455_035624 {REF} {Length: 4558} {Pfam: Sulfate permease family [PF00916.22, score=254.9]; STAS domain [PF01740.23, score=82.3]} {Human: ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [Score=364, Expect=1e-117]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [Score=360, Expect=3e-116]} {Dmel: FBgn0036770, Prestin, [Score=281, Expect=7e-86]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=274, Expect=4e-85]} {Smed: dd_Smed_v6_4250_0_4, dd_Smed_v6_4250_0_4, [Score=468, Expect=9e-158]} {RNA1509_27065} {RNA1310_5442.2} {RNA815_6518}

Mlig455_048255 {REF} {Length: 5310} {Pfam: Sulfate permease family [PF00916.22, score=382.6]; STAS domain [PF01740.23, score=81.1]} {Human: ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [RH, Score=464, Expect=4e-151]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [RH, Score=465, Expect=7e-152]} {Dmel: FBgn0036770, Prestin, [RH, Score=371, Expect=6e-116]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [RH, Score=375, Expect=4e-119]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [RH, Score=633, Expect=0.0]} {RNA1509_27065} {RNA1310_5442.2} {RNA815_6518}

Mlig455_048315 {REF} {Length: 4387} {Pfam: Sulfate permease family [PF00916.22, score=260.9]; STAS domain [PF01740.23, score=82.2]} {Human: ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [Score=360, Expect=2e-114]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [Score=359, Expect=2e-114]} {Dmel: FBgn0036770, Prestin, [Score=248, Expect=1e-72]} {Celegans: WBGene00010788, sulp-4, Anion transporter SULP-4; SULfate Permease family, [Score=285, Expect=3e-86]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [Score=477, Expect=5e-160]} {RNA1509_27065} {RNA1310_5442.2} {RNA815_6518}
72. MligTC455_19298 52 1.08 Mlig455_007404

Neo: -

Age: -

IRX4 1.907 - - - - 0.976 0.931 Mlig455_007404 {REF} {Length: 1775} {Pfam: Homeobox KN domain [PF05920.13, score=53.9]; Homeodomain [PF00046.31, score=30.1]} {Human: ENSG00000113430, IRX4, iroquois homeobox 4, [RH, Score=149, Expect=2e-39]; ENSG00000159387, IRX6, iroquois homeobox 6, [RH, Score=147, Expect=6e-39]} {Mouse: ENSMUSG00000021604, Irx4, Iroquois homeobox 4, [RH, Score=150, Expect=5e-40]; ENSMUSG00000031738, Irx6, Iroquois homeobox 6, [RH, Score=145, Expect=1e-38]} {Dmel: FBgn0015919, caup, caupolican, [RH, Score=153, Expect=3e-40]} {Celegans: WBGene00007984, irx-1, Putative iroquois-class homeodomain protein irx-1, [RH, Score=124, Expect=1e-31]} {Smed: dd_Smed_v6_17352_0_1, dd_Smed_v6_17352_0_1, [RH, Score=159, Expect=3e-44]} {RNA1310_58105} {RNA815_61910}
73. MligTC455_42798 138 2.86 Mlig455_005345, Mlig455_005460

Neo: -

Age: logFC(26M/2M)=0.617

CLEC3A 1.901 0.963 0.938 - - - -

Mlig455_005345 {REF} {Length: 1469} {Pfam: Lectin C-type domain [PF00059.23, score=22.7]} {RNA1509_35720} {RNA1310_2191.3} {RNA815_1425.1}

Mlig455_005460 {REF} {Length: 722} {Pfam: Lectin C-type domain [PF00059.23, score=25.6]} {Human: ENSG00000166509, CLEC3A, C-type lectin domain family 3 member A, [Score=47.8, Expect=3e-06]} {RNA1509_35720} {RNA1310_2191.3} {RNA815_1425.1}
74. MligTC455_50296 55 1.15 Mlig455_051593

Neo: -

Age: Up-Down-Up

1.891 - - - - 0.938 0.953 Mlig455_051593 {REF} {Length: 2388} {RNA1310_48051} {RNA815_14784}
75. MligTC455_46517 122 2.54 Mlig455_051299

Neo: -

Age: -

Region-enriched R2: 3.450/0.03846

ERC2 1.88 - - - 0.976 0.904 - Mlig455_051299 {REF} {Length: 6303} {TRANSSPLICED} {Pfam: RIM-binding protein of the cytomatrix active zone [PF10174.11, score=167.4]; Tropomyosin like [PF12718.9, score=22.2]; Autophagy protein 16 (ATG16) [PF08614.13, score=20.7]} {Human: ENSG00000187672, ERC2, ELKS/RAB6-interacting/CAST family member 2, [Score=143, Expect=1e-33]} {Mouse: ENSMUSG00000040640, Erc2, ELKS/RAB6-interacting/CAST family member 2, [Score=143, Expect=6e-34]} {Dmel: FBgn0259246, brp, bruchpilot, [Score=117, Expect=1e-25]} {Smed: dd_Smed_v6_12278_0_1, dd_Smed_v6_12278_0_1, [Score=211, Expect=9e-55]} {RNA1509_45174, RNA1509_45537} {RNA1310_5220.1, RNA1509_45537} {RNA1509_45537, RNA815_13350}
76. MligTC455_23269 1700 35.41 Mlig455_058823

Neo: -

Age: -

Region-enriched R8: 1.965/0.00066

SYT1 1.87 - - - 0.897 0.973 - Mlig455_058823 {REF} {Length: 3328} {Pfam: C2 domain [PF00168.32, score=181.3]; CEP76 C2 domain [PF15627.8, score=21.0]; Phosphoinositide 3-kinase C2 [PF00792.26, score=20.4]} {Human: ENSG00000067715, SYT1, synaptotagmin 1, [RH, Score=436, Expect=4e-151]} {Mouse: ENSMUSG00000035864, Syt1, synaptotagmin I, [RH, Score=435, Expect=4e-151]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=496, Expect=1e-174]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=432, Expect=6e-150]} {Smed: dd_Smed_v6_6730_0_1, dd_Smed_v6_6730_0_1, [Score=542, Expect=0.0]} {RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080} {RNA1310_21689, RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080} {RNA1509_10517, RNA1509_25740, RNA1509_36281, RNA1509_40080, RNA815_10622.1}
77. MligTC455_09224 21 0.43 Mlig455_038078

Neo: -

Age: -

1.868 - - - 0.996 - 0.872 Mlig455_038078 {REF} {Length: 771} {Pfam: PAN domain [PF00024.28, score=28.0]} {RNA1509_46267} {RNA1310_51656} {RNA815_32275.1}
78. MligTC455_50734 175 3.66 Mlig455_044294

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.054/0.00263
Region-enriched R3: 3.364/0.00377

CHRNA3 1.864 - - - 0.894 - 0.970 Mlig455_044294 {REF} {Length: 1830} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=242.4]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=225.5]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=373, Expect=1e-123]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=365, Expect=1e-120]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=360, Expect=9e-119]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=358, Expect=6e-118]} {Mouse: ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=376, Expect=3e-125]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=374, Expect=4e-124]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=450, Expect=4e-154]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=381, Expect=2e-127]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [RH, Score=651, Expect=0.0]} {RNA1509_45903} {RNA1310_14580} {RNA815_10044.1}
79. MligTC455_41968 247 5.15 Mlig455_048152

Neo: -

Age: -

Region-specific R2: 5.996

Region-enriched R2: 5.206/0.00199

1.855 - 0.905 - 0.950 - - Mlig455_048152 {REF} {Length: 932} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=22.6]} {RNA1509_40628} {RNA1310_50753} {RNA815_21607}
80. MligTC455_51780 138 2.88 Mlig455_046894

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.174/0.00338

PNPO 1.855 - - - 0.962 0.893 - Mlig455_046894 {REF} {Length: 2339} {Pfam: Pyridoxamine 5'-phosphate oxidase [PF01243.22, score=78.4]; Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region [PF10590.11, score=69.2]; Pyridoxamine 5'-phosphate oxidase [PF12766.9, score=22.3]} {Human: ENSG00000108439, PNPO, pyridoxamine 5'-phosphate oxidase, [Score=182, Expect=7e-57]} {Mouse: ENSMUSG00000018659, Pnpo, pyridoxine 5'-phosphate oxidase, [RH, Score=184, Expect=1e-57]} {Dmel: FBgn0051472, sgll, sugarlethal, [Score=168, Expect=6e-52]} {Celegans: WBGene00018996, F57B9.1, Putative pyridoxamine 5'-phosphate oxidase, [RH, Score=200, Expect=1e-64]} {Smed: dd_Smed_v6_5086_0_1, dd_Smed_v6_5086_0_1, [RH, Score=177, Expect=2e-55]} {RNA1509_54079} {RNA1310_31564.1, RNA1509_54079} {RNA1509_54079, RNA815_34098}
81. MligTC455_47234 19 0.39 Mlig455_051300

Neo: -

Age: Down-Up-Down

SCNN1B 1.853 - - - 0.891 0.962 - Mlig455_051300 {REF} {Length: 1753} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=169.2]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=55.8, Expect=1e-07]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=57.8, Expect=2e-08]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=85.9, Expect=1e-17]} {RNA1310_54586}
82. MligTC455_15598 45 0.94 Mlig455_021461

Neo: -

Age: Down-Up-Up

1.852 - - - - 0.900 0.952 Mlig455_021461 {REF} {Length: 2020} {RNA1310_35982.1} {RNA815_27626}
83. MligTC455_26243 7282 151.7 Mlig455_058373

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.861

Region-enriched R2: 2.532/0.00002

PPIB 1.852 - - - 0.969 - 0.883 Mlig455_058373 {REF} {Length: 1101} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=123.3]} {Human: ENSG00000166794, PPIB, peptidylprolyl isomerase B, [Score=154, Expect=2e-47]} {Mouse: ENSMUSG00000032383, Ppib, peptidylprolyl isomerase B, [Score=153, Expect=4e-47]} {Dmel: FBgn0034753, CG2852, [Score=131, Expect=6e-39]} {Celegans: WBGene00000882, cyn-6, Peptidyl-prolyl cis-trans isomerase 6, [Score=139, Expect=4e-42]} {Smed: dd_Smed_v6_348_0_1, dd_Smed_v6_348_0_1, [Score=233, Expect=6e-79]} {RNA1509_11405, RNA1509_2163} {RNA1310_10180, RNA1509_11405} {RNA1509_11405, RNA815_2338.1}
84. MligTC455_47309 569 11.85 Mlig455_047902, Mlig455_047990

Neo: -

Age: logFC(26M/2M)=-0.322

NSF 1.852 - - - 0.878 0.974 -

Mlig455_047902 {REF} {Length: 3210} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=169.7]; AAA+ lid domain [PF17862.3, score=38.2]; AAA ATPase domain [PF13191.8, score=34.7]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=32.6]; AAA domain [PF13401.8, score=29.7]; AAA domain [PF13173.8, score=29.2]; TIP49 P-loop domain [PF06068.15, score=28.7]; NACHT domain [PF05729.14, score=27.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=26.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=25.6]; AAA domain [PF13238.8, score=25.5]; AAA domain [PF13671.8, score=22.9]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=22.5]; RNA helicase [PF00910.24, score=22.0]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=21.8]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=21.5]; ATPase domain predominantly from Archaea [PF01637.20, score=21.2]; Magnesium chelatase, subunit ChlI [PF01078.23, score=20.7]} {Human: ENSG00000073969, NSF, N-ethylmaleimide sensitive factor, vesicle fusing ATPase, [RH, Score=759, Expect=0.0]; ENSG00000278174, NSF, N-ethylmaleimide sensitive factor, vesicle fusing ATPase, [RH, Score=759, Expect=0.0]; ENSG00000276262, NSF, N-ethylmaleimide sensitive factor, vesicle fusing ATPase, [RH, Score=759, Expect=0.0]} {Mouse: ENSMUSG00000034187, Nsf, N-ethylmaleimide sensitive fusion protein, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0266464, Nsf2, N-ethylmaleimide-sensitive factor 2, [RH, Score=816, Expect=0.0]} {Celegans: WBGene00003818, nsf-1, Vesicle-fusing ATPase, [RH, Score=676, Expect=0.0]} {Smed: dd_Smed_v6_3364_0_1, dd_Smed_v6_3364_0_1, [RH, Score=631, Expect=0.0]} {RNA1509_35440} {RNA1310_7474} {RNA815_4714}

Mlig455_047990 {REF} {Length: 3208} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=168.7]; AAA+ lid domain [PF17862.3, score=37.8]; THAP domain [PF05485.14, score=35.8]; AAA ATPase domain [PF13191.8, score=33.6]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=33.2]; AAA domain [PF13401.8, score=28.4]; AAA domain [PF13173.8, score=28.3]; TIP49 P-loop domain [PF06068.15, score=27.9]; NACHT domain [PF05729.14, score=25.9]; AAA domain (dynein-related subfamily) [PF07728.16, score=25.4]; AAA domain (Cdc48 subfamily) [PF07724.16, score=24.9]; AAA domain [PF13238.8, score=24.7]; AAA domain [PF13671.8, score=22.1]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=21.8]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=21.5]; RNA helicase [PF00910.24, score=21.3]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=21.0]; Magnesium chelatase, subunit ChlI [PF01078.23, score=20.0]; ATPase domain predominantly from Archaea [PF01637.20, score=19.8]} {Human: ENSG00000276262, NSF, N-ethylmaleimide sensitive factor, vesicle fusing ATPase, [RH, Score=760, Expect=0.0]; ENSG00000278174, NSF, N-ethylmaleimide sensitive factor, vesicle fusing ATPase, [RH, Score=760, Expect=0.0]; ENSG00000073969, NSF, N-ethylmaleimide sensitive factor, vesicle fusing ATPase, [RH, Score=760, Expect=0.0]} {Mouse: ENSMUSG00000034187, Nsf, N-ethylmaleimide sensitive fusion protein, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0266464, Nsf2, N-ethylmaleimide-sensitive factor 2, [RH, Score=818, Expect=0.0]} {Celegans: WBGene00003818, nsf-1, Vesicle-fusing ATPase, [RH, Score=677, Expect=0.0]} {Smed: dd_Smed_v6_3364_0_1, dd_Smed_v6_3364_0_1, [RH, Score=630, Expect=0.0]} {RNA1509_35440} {RNA1310_7474} {RNA815_4714}
85. MligTC455_47160 747 15.56 Mlig455_021750

Neo: -

Age: logFC(26M/2M)=-0.246

FAM184A 1.848 - - - - 0.955 0.893 Mlig455_021750 {REF} {Length: 3705} {Pfam: Family with sequence similarity 184, A and B [PF15665.7, score=130.1]} {Human: ENSG00000111879, FAM184A, family with sequence similarity 184 member A, [RH, Score=340, Expect=5e-99]} {Mouse: ENSMUSG00000019856, Fam184a, family with sequence similarity 184, member A, [RH, Score=308, Expect=7e-88]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=60.8, Expect=5e-09]} {Smed: dd_Smed_v6_16975_0_1, dd_Smed_v6_16975_0_1, [RH, Score=264, Expect=3e-73]} {RNA1509_5806} {RNA1310_3258.1, RNA1509_5806} {RNA1509_5806, RNA815_936}
86. MligTC455_53468 14 0.28 Mlig455_070377

Neo: -

Age: -

1.846 - - - 0.977 0.869 - Mlig455_070377 {REF} {Length: 2927} {Pfam: Glycine rich protein [PF12810.9, score=23.6]} {RNA1509_10020} {RNA1310_33363.2} {RNA815_25152}
87. MligTC455_46173 63 1.3 Mlig455_032091

Neo: Irradiation

Age: Up-Down-Up

SRR 1.834 - - - 0.863 0.971 - Mlig455_032091 {REF} {Length: 2590} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=208.5]; ACT domain [PF01842.27, score=19.8]} {Human: ENSG00000167720, SRR, serine racemase, [Score=129, Expect=2e-32]} {Mouse: ENSMUSG00000001323, Srr, serine racemase, [Score=105, Expect=4e-24]} {Dmel: FBgn0037684, CG8129, [Score=373, Expect=5e-123]} {Celegans: WBGene00010456, K01C8.1, [Score=407, Expect=5e-136]} {Smed: dd_Smed_v6_6737_0_1, dd_Smed_v6_6737_0_1, [Score=474, Expect=7e-163]} {RNA1509_48789} {RNA1310_15074} {RNA815_9364}
88. MligTC455_50601 21 0.44 Mlig455_018462

Neo: -

Age: -

1.833 - - - 0.856 0.977 - Mlig455_018462 {REF} {Length: 2878} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=164.0]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=117, Expect=1e-27]} {RNA1310_8235} {RNA815_10456.1}
89. MligTC455_13975 63 1.31 Mlig455_070810

Neo: -

Age: -

Region-enriched R2: 7.513/0.00519

1.831 - - - - 0.962 0.869 Mlig455_070810 {REF} {Length: 1542} {Pfam: Otopetrin [PF03189.15, score=108.9]} {Dmel: FBgn0031514, CG3332, [Score=74.3, Expect=3e-14]} {Celegans: WBGene00015035, otpl-1, OToPetrin-Like, [Score=47.8, Expect=9e-06]} {Smed: dd_Smed_v6_13612_0_3, dd_Smed_v6_13612_0_3, [Score=119, Expect=2e-29]} {RNA1310_93602} {RNA815_48323}
90. MligTC455_37270 86 1.79 Mlig455_022293

Neo: -

Age: -

CASP3 1.819 - - - 0.956 0.863 - Mlig455_022293 {REF} {Length: 2773} {Pfam: Caspase domain [PF00656.24, score=93.1]; Ankyrin repeats (3 copies) [PF12796.9, score=77.8]; Ankyrin repeats (many copies) [PF13857.8, score=62.2]; Ankyrin repeats (many copies) [PF13637.8, score=56.0]; Ankyrin repeat [PF13606.8, score=39.1]; Ankyrin repeat [PF00023.32, score=28.2]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=109, Expect=7e-26]; ENSG00000003400, CASP10, caspase 10, [Score=107, Expect=9e-24]; ENSG00000165806, CASP7, caspase 7, [Score=104, Expect=2e-23]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=106, Expect=9e-25]; ENSMUSG00000031628, Casp3, caspase 3, [Score=103, Expect=3e-24]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=96.3, Expect=3e-21]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=81.6, Expect=9e-17]} {Smed: dd_Smed_v6_3121_1_1, dd_Smed_v6_3121_1_1, [Score=102, Expect=3e-24]} {RNA1509_54818} {RNA1310_7187, RNA1509_54818} {RNA1509_54818, RNA815_8712}
91. MligTC455_10786 15 0.32 Mlig455_018164

Neo: -

Age: -

1.818 - - - 0.968 - 0.850 Mlig455_018164 {REF} {Length: 1819} {Pfam: F5/8 type C domain [PF00754.27, score=24.0]} {Smed: dd_Smed_v6_15258_0_1, dd_Smed_v6_15258_0_1, [RH, Score=57.8, Expect=5e-10]} {RNA1310_114361}
92. MligTC455_49620 290 6.04 Mlig455_001138, Mlig455_001300

Neo: -

Age: -

Region-enriched R2: 5.198/0.00000

ELAVL3, ELAVL4 1.815 - - - 0.833 0.982 -

Mlig455_001138 {REF} {Length: 3131} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=206.7]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=37.5]; Occluded RNA-recognition motif [PF16842.7, score=27.0]} {Human: ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=268, Expect=6e-85]; ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=268, Expect=3e-85]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=268, Expect=2e-84]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [RH, Score=270, Expect=2e-87]} {Dmel: FBgn0010263, Rbp9, RNA-binding protein 9, [Score=273, Expect=2e-86]} {Celegans: WBGene00001368, exc-7, [RH, Score=327, Expect=6e-107]} {Smed: dd_Smed_v6_13151_0_1, dd_Smed_v6_13151_0_1, [RH, Score=269, Expect=8e-84]} {RNA1509_28072} {RNA1310_22289} {RNA815_15133}

Mlig455_001300 {REF} {Length: 3150} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=203.6]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=36.4]; Occluded RNA-recognition motif [PF16842.7, score=27.0]} {Human: ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=274, Expect=4e-87]; ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=271, Expect=6e-86]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=268, Expect=3e-85]; ENSG00000066044, ELAVL1, ELAV like RNA binding protein 1, [Score=262, Expect=3e-83]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [RH, Score=271, Expect=7e-88]} {Dmel: FBgn0010263, Rbp9, RNA-binding protein 9, [Score=270, Expect=4e-85]} {Celegans: WBGene00001368, exc-7, [RH, Score=326, Expect=1e-106]} {Smed: dd_Smed_v6_11311_0_2, dd_Smed_v6_11311_0_2, [RH, Score=300, Expect=2e-97]} {RNA1509_28072} {RNA1310_22289} {RNA815_15133}
93. MligTC455_46004 40 0.83 Mlig455_053399

Neo: -

Age: -

1.811 - - - 0.989 - 0.822 Mlig455_053399 {REF} {Length: 583} {NoTransDecoderORF} {RNA1310_66147} {RNA815_35487}
94. MligTC455_13773 101 2.1 Mlig455_010827

Neo: -

Age: -

1.81 - - - 0.958 0.852 - Mlig455_010827 {REF} {Length: 304} {NoTransDecoderORF} {RNA1509_22845} {RNA1310_11632} {RNA815_10000}
95. MligTC455_28903 55 1.14 Mlig455_030222, Mlig455_067999

Neo: -

Age: Up-Down-Down

FAT4 1.808 0.852 - - 0.956 - -

Mlig455_030222 {REF} {Length: 8676} {Pfam: Cadherin domain [PF00028.19, score=744.0]; Cadherin-like [PF16184.7, score=94.9]; Cadherin-like [PF08266.14, score=40.7]; RET Cadherin like domain 1 [PF17756.3, score=23.4]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=518, Expect=1e-147]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=531, Expect=9e-152]} {Dmel: FBgn0001075, ft, fat, [Score=479, Expect=9e-136]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=268, Expect=1e-71]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=260, Expect=4e-69]} {RNA1509_58830} {RNA1310_15141, RNA1509_58830} {RNA1509_58830, RNA815_18357}

Mlig455_067999 {REF} {Length: 8147} {Pfam: Cadherin domain [PF00028.19, score=745.9]; Cadherin-like [PF16184.7, score=94.8]; Cadherin-like [PF08266.14, score=40.9]; RET Cadherin like domain 1 [PF17756.3, score=23.3]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=519, Expect=6e-148]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=531, Expect=7e-152]} {Dmel: FBgn0001075, ft, fat, [Score=476, Expect=8e-135]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=268, Expect=1e-71]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=261, Expect=2e-69]} {RNA1509_58830} {RNA1310_15141} {RNA815_18357}
96. MligTC455_19938 250 5.2 Mlig455_063706

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.458

Region-enriched R3: 3.513/0.03723

NKX2-2 1.807 - - - 0.966 - 0.841 Mlig455_063706 {REF} {Length: 2739} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=3e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=2e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.9, Expect=8e-23]} {Smed: dd_Smed_v6_2716_0_4, dd_Smed_v6_2716_0_4, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1, RNA1509_27298} {RNA1509_27298, RNA815_30453}
97. MligTC455_35411 583 12.15 Mlig455_064235

Neo: -

Age: -

PPP3CA 1.806 - - - 0.851 0.955 - Mlig455_064235 {REF} {Length: 3595} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=156, Expect=8e-46]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=149, Expect=4e-43]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=158, Expect=1e-46]} {Dmel: FBgn0011826, Pp2B-14D, Protein phosphatase 2B at 14D, [Score=159, Expect=1e-46]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=115, Expect=1e-30]} {Smed: dd_Smed_v6_5669_1_2, dd_Smed_v6_5669_1_2, [Score=155, Expect=7e-49]} {RNA1509_42566} {RNA1310_30586} {RNA815_21103.2}
98. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 1.802 - 0.962 - - 0.840 -

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
99. MligTC455_53307 32 0.67 Mlig455_018445

Neo: -

Age: Up-Down-Down

SLC4A11 1.797 - - - - 0.988 0.809 Mlig455_018445 {REF} {Length: 3675} {Pfam: HCO3- transporter family [PF00955.23, score=519.3]; Band 3 cytoplasmic domain [PF07565.15, score=37.0]; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 [PF00359.24, score=23.1]} {Human: ENSG00000088836, SLC4A11, solute carrier family 4 member 11, [RH, Score=536, Expect=2e-175]} {Mouse: ENSMUSG00000074796, Slc4a11, solute carrier family 4, sodium bicarbonate transporter-like, member 11, [RH, Score=529, Expect=9e-174]} {Dmel: FBgn0036043, CG8177, [Score=256, Expect=1e-70]} {Celegans: WBGene00019018, abts-3, Anion transporter ABTS-3; Anion/Bicarbonate TranSporter family, [RH, Score=690, Expect=0.0]} {Smed: dd_Smed_v6_12290_0_1, dd_Smed_v6_12290_0_1, [RH, Score=929, Expect=0.0]} {RNA1509_57265} {RNA1310_5995, RNA1509_57265} {RNA1509_57265, RNA815_19456}
100. MligTC455_51537 225 4.69 Mlig455_064569

Neo: -

Age: -

1.795 - 0.963 - - 0.832 - Mlig455_064569 {REF} {Length: 2141} {RNA1310_34295.1} {RNA815_22630}

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