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Results for MligTC455_18564

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}

Cumulative graph for MligTC455_18564

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.719 2.5 0.33729 0.98360
RegionR2 2.416 2.5 0.00078 0.01839
RegionR3 -0.557 2.5 0.47878 0.98216
RegionR4 -2.198 2.5 0.02280 0.11191
RegionR5 -2.368 2.5 0.00402 0.02942
RegionR6 -0.492 2.5 0.54502 1.00000
RegionR7 1.287 2.5 0.10943 0.62791
RegionR8 0.192 2.5 0.86688 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.013 2.5 0.62855 1.00000
RegenerationR2 -0.433 2.5 0.30275 0.74433
RegenerationR3 -0.843 2.5 0.28697 0.71885
RegenerationR4 0.419 2.5 0.58300 0.90630
RegenerationR5 0.213 2.5 0.76507 0.97724
RegenerationR6 -0.657 2.5 0.41051 0.74435
RegenerationBL -6.134 2.5 0.00431 0.05967
RegenerationTP -1.104 2.5 0.34188 0.78479


Genes with expression patterns similar to MligTC455_18564

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
2. MligTC455_52874 382 7.96 Mlig455_026014, Mlig455_070442

Neo: -

Age: -

CDH23 5.006 0.860 0.707 0.947 0.739 0.767 0.986

Mlig455_026014 {REF} {Length: 10931} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=362.8]; Cadherin-like [PF16184.7, score=40.0]; Cadherin-like [PF08266.14, score=32.1]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=327, Expect=4e-90]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=327, Expect=2e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=498, Expect=9e-149]} {RNA1509_48951} {RNA1310_475.1} {RNA815_321.1}

Mlig455_070442 {REF} {Length: 10801} {TRANSSPLICED} {Pfam: Cadherin domain [PF00028.19, score=364.1]; Cadherin-like [PF16184.7, score=39.7]; Cadherin-like [PF08266.14, score=30.9]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=323, Expect=4e-89]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=326, Expect=4e-90]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=404, Expect=8e-116]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=211, Expect=1e-54]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=495, Expect=1e-147]} {RNA1509_44393, RNA1509_48951} {RNA1310_475.1, RNA1509_44393} {RNA1509_44393, RNA815_321.1}
3. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

CCDC151 4.391 - 0.801 0.961 0.773 0.907 0.949 Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
4. MligTC455_45721 1254 26.12 Mlig455_040703, Mlig455_064572

Neo: -

Age: logFC(26M/2M)=-0.404

PTPDC1 4.039 0.853 0.748 - 0.760 0.727 0.951

Mlig455_040703 {REF} {Length: 2564} {TRANSSPLICED} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=29.2]; Protein-tyrosine phosphatase [PF00102.29, score=28.9]; Cyclin-dependent kinase inhibitor 3 (CDKN3) [PF05706.14, score=18.4]} {Human: ENSG00000158079, PTPDC1, protein tyrosine phosphatase domain containing 1, [Score=223, Expect=9e-64]} {Mouse: ENSMUSG00000038042, Ptpdc1, protein tyrosine phosphatase domain containing 1, [Score=220, Expect=1e-62]} {Dmel: FBgn0031952, cdc14, cell division cycle 14, [Score=57.8, Expect=2e-08]} {Celegans: WBGene00020444, T12B3.1, [Score=162, Expect=7e-44]} {Smed: dd_Smed_v6_13749_0_1, dd_Smed_v6_13749_0_1, [Score=199, Expect=3e-57]} {RNA1509_19142, RNA1509_54918} {RNA1310_14761.1, RNA1509_54918} {RNA1509_54918, RNA815_14825}

Mlig455_064572 {REF} {Length: 2822} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=29.2]; Protein-tyrosine phosphatase [PF00102.29, score=28.8]; Cyclin-dependent kinase inhibitor 3 (CDKN3) [PF05706.14, score=18.3]} {Human: ENSG00000158079, PTPDC1, protein tyrosine phosphatase domain containing 1, [Score=223, Expect=2e-63]} {Mouse: ENSMUSG00000038042, Ptpdc1, protein tyrosine phosphatase domain containing 1, [Score=219, Expect=2e-62]} {Dmel: FBgn0031952, cdc14, cell division cycle 14, [Score=57.8, Expect=2e-08]} {Celegans: WBGene00020444, T12B3.1, [Score=162, Expect=6e-44]} {Smed: dd_Smed_v6_13749_0_1, dd_Smed_v6_13749_0_1, [Score=199, Expect=3e-57]} {RNA1509_19142} {RNA1310_14761.1, RNA1509_19142} {RNA1509_19142, RNA815_14825}
5. MligTC455_33463 240 4.99 Mlig455_023684

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.110/0.00054

PKD1L2 3.81 - 0.922 - 0.978 0.938 0.972 Mlig455_023684 {REF} {Length: 12137} {Pfam: Polycystin cation channel [PF08016.14, score=271.5]; PKD domain [PF00801.22, score=88.3]; PLAT/LH2 domain [PF01477.25, score=72.6]; PKD domain [PF18911.2, score=49.9]; Ion transport protein [PF00520.33, score=46.0]; F5/8 type C domain [PF00754.27, score=33.9]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [RH, Score=263, Expect=2e-69]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=272, Expect=3e-72]} {Dmel: FBgn0050048, CG30048, [Score=57.4, Expect=3e-07]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=144, Expect=2e-33]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=518, Expect=3e-147]} {RNA1509_5488} {RNA1310_100} {RNA815_3211}
6. MligTC455_41669 480 10.01 Mlig455_040778, Mlig455_064613

Neo: -

Age: Down-Down-Up

3.737 0.907 - 0.924 - 0.926 0.980

Mlig455_040778 {REF} {Length: 2233} {RNA1310_31511} {RNA815_21534}

Mlig455_064613 {REF} {Length: 1332} {RNA1310_32935} {RNA815_21534}
7. MligTC455_47080 362 7.54 Mlig455_037356

Neo: -

Age: -

Region-enriched R2: 2.691/0.00566

SSUH2 3.706 - - 0.894 0.878 0.960 0.974 Mlig455_037356 {REF} {Length: 1984} {Pfam: DnaJ central domain [PF00684.21, score=20.9]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=5e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=90.9, Expect=7e-20]} {RNA1509_29510} {RNA1310_15488, RNA1509_29510} {RNA1509_29510, RNA815_5650}
8. MligTC455_35019 168 3.49 Mlig455_046994

Neo: -

Age: -

ASIC4 3.694 - - 0.964 0.963 0.782 0.985 Mlig455_046994 {REF} {Length: 4001} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.4]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=76.3, Expect=8e-14]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=72.8, Expect=8e-13]} {Smed: dd_Smed_v6_15233_0_1, dd_Smed_v6_15233_0_1, [RH, Score=103, Expect=1e-22]} {RNA1509_33816} {RNA1310_3176, RNA1509_33816} {RNA1509_33816, RNA815_12439}
9. MligTC455_49020 172 3.58 Mlig455_035624, Mlig455_048255, Mlig455_048315

Neo: -

Age: logFC(26M/2M)=-0.385

Region-enriched R2: 3.728/0.03083

SLC26A5 3.671 0.987 0.789 - 0.951 - 0.944

Mlig455_035624 {REF} {Length: 4558} {Pfam: Sulfate permease family [PF00916.22, score=254.9]; STAS domain [PF01740.23, score=82.3]} {Human: ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [Score=364, Expect=1e-117]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [Score=360, Expect=3e-116]} {Dmel: FBgn0036770, Prestin, [Score=281, Expect=7e-86]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=274, Expect=4e-85]} {Smed: dd_Smed_v6_4250_0_4, dd_Smed_v6_4250_0_4, [Score=468, Expect=9e-158]} {RNA1509_27065} {RNA1310_5442.2} {RNA815_6518}

Mlig455_048255 {REF} {Length: 5310} {Pfam: Sulfate permease family [PF00916.22, score=382.6]; STAS domain [PF01740.23, score=81.1]} {Human: ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [RH, Score=464, Expect=4e-151]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [RH, Score=465, Expect=7e-152]} {Dmel: FBgn0036770, Prestin, [RH, Score=371, Expect=6e-116]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [RH, Score=375, Expect=4e-119]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [RH, Score=633, Expect=0.0]} {RNA1509_27065} {RNA1310_5442.2} {RNA815_6518}

Mlig455_048315 {REF} {Length: 4387} {Pfam: Sulfate permease family [PF00916.22, score=260.9]; STAS domain [PF01740.23, score=82.2]} {Human: ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [Score=360, Expect=2e-114]} {Mouse: ENSMUSG00000029015, Slc26a5, solute carrier family 26, member 5, [Score=359, Expect=2e-114]} {Dmel: FBgn0036770, Prestin, [Score=248, Expect=1e-72]} {Celegans: WBGene00010788, sulp-4, Anion transporter SULP-4; SULfate Permease family, [Score=285, Expect=3e-86]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [Score=477, Expect=5e-160]} {RNA1509_27065} {RNA1310_5442.2} {RNA815_6518}
10. MligTC455_48848 282 5.87 Mlig455_005151, Mlig455_021613

Neo: -

Age: -

Region-specific R2: 4.764

Region-enriched R2: 5.813/0.00000

SYT3 3.652 0.930 - - 0.961 0.818 0.943

Mlig455_005151 {REF} {Length: 1574} {Pfam: C2 domain [PF00168.32, score=55.1]} {Human: ENSG00000213023, SYT3, synaptotagmin 3, [Score=68.6, Expect=5e-12]; ENSG00000011347, SYT7, synaptotagmin 7, [Score=67.0, Expect=1e-11]} {Mouse: ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=69.3, Expect=2e-12]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=63.2, Expect=1e-10]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=66.6, Expect=5e-12]} {Smed: dd_Smed_v6_25279_0_1, dd_Smed_v6_25279_0_1, [Score=85.1, Expect=2e-18]} {RNA1310_20857} {RNA815_8396}

Mlig455_021613 {REF} {Length: 1574} {Pfam: C2 domain [PF00168.32, score=55.1]} {Human: ENSG00000213023, SYT3, synaptotagmin 3, [Score=68.6, Expect=5e-12]; ENSG00000011347, SYT7, synaptotagmin 7, [Score=67.0, Expect=1e-11]} {Mouse: ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=69.3, Expect=2e-12]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=63.2, Expect=1e-10]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=66.6, Expect=5e-12]} {Smed: dd_Smed_v6_25279_0_1, dd_Smed_v6_25279_0_1, [Score=85.1, Expect=2e-18]} {RNA1310_20857} {RNA815_8396}
11. MligTC455_15330 373 7.77 Mlig455_020220

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.289

3.643 - 0.894 0.891 - 0.878 0.980 Mlig455_020220 {REF} {Length: 2115} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=41.4]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=82.0, Expect=3e-20]} {RNA1509_28885, RNA1509_54654} {RNA1310_42962.2, RNA1509_28885, RNA1509_54654} {RNA1509_28885, RNA1509_54654, RNA815_23071}
12. MligTC455_16908 161 3.35 Mlig455_046916

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.397

Region-enriched R2: 2.938/0.02849

SLC17A6 3.643 - - 0.860 0.882 0.935 0.966 Mlig455_046916 {REF} {Length: 3198} {Pfam: Major Facilitator Superfamily [PF07690.18, score=172.0]; Uncharacterised MFS-type transporter YbfB [PF06779.16, score=19.6]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=548, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=542, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=536, Expect=0.0]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=551, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=547, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=543, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=482, Expect=6e-163]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=479, Expect=7e-163]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=591, Expect=0.0]} {RNA1509_38152} {RNA1310_23072, RNA1509_38152} {RNA1509_38152, RNA815_14894}
13. MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2 3.643 - - 0.978 0.732 0.956 0.977

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}
14. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 3.623 - 0.879 - 0.861 0.932 0.951 Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
15. MligTC455_26765 686 14.29 Mlig455_006971

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.201/0.00046

3.617 0.942 - 0.738 - 0.958 0.979 Mlig455_006971 {REF} {Length: 6360} {Pfam: Cadherin domain [PF00028.19, score=29.2]} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [RH, Score=328, Expect=1e-93]} {RNA1509_19813, RNA1509_5311} {RNA1310_621, RNA1509_19813, RNA1509_5311} {RNA1509_19813, RNA1509_5311, RNA815_183.1}
16. MligTC455_18920 299 6.22 Mlig455_052039

Neo: -

Age: Down-Up-Down

Region-enriched R8: 3.175/0.01587

RTN4R 3.613 - 0.900 - 0.888 0.874 0.951 Mlig455_052039 {REF} {Length: 1911} {Pfam: Leucine rich repeat [PF13855.8, score=113.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=46.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=24.5]} {Human: ENSG00000040608, RTN4R, reticulon 4 receptor, [Score=73.2, Expect=2e-13]} {Mouse: ENSMUSG00000111113, Rtn4r, reticulon 4 receptor, [Score=72.8, Expect=2e-13]; ENSMUSG00000043811, Rtn4r, reticulon 4 receptor, [Score=72.8, Expect=2e-13]} {Dmel: FBgn0004364, 18w, 18 wheeler, [Score=71.2, Expect=7e-13]} {Celegans: WBGene00001443, fli-1, Protein flightless-1 homolog, [Score=56.6, Expect=2e-08]} {Smed: dd_Smed_v6_12111_0_1, dd_Smed_v6_12111_0_1, [Score=48.1, Expect=8e-06]} {RNA1310_19257.1} {RNA815_9099}
17. MligTC455_47393 241 5.03 Mlig455_008718, Mlig455_063579

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.683/0.00849

CALM2 3.599 - - 0.892 0.928 0.819 0.960

Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211}

Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211}
18. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

3.597 - 0.868 - 0.835 0.915 0.979 Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
19. MligTC455_35259 2265 47.19 Mlig455_040978

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.606

Region-enriched R2: 1.588/0.00387

ADGRL2 3.594 - 0.707 - 0.914 0.984 0.989 Mlig455_040978 {REF} {Length: 10808} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=86.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=76.2]; PDZ domain [PF17820.3, score=67.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=52.3]; PDZ domain [PF13180.8, score=36.4]; ZU5 domain [PF00791.22, score=30.8]; Guanylate kinase [PF00625.23, score=22.4]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=174, Expect=1e-42]} {Mouse: ENSMUSG00000034917, Tjp3, tight junction protein 3, [RH, Score=172, Expect=9e-43]} {Dmel: FBgn0262614, pyd, polychaetoid, [RH, Score=232, Expect=8e-61]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=174, Expect=4e-43]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_17602, RNA1509_52679, RNA1509_58629} {RNA1310_236.2, RNA1509_17602, RNA1509_58629} {RNA1509_17602, RNA1509_58629, RNA815_77.1}
20. MligTC455_51764 938 19.55 Mlig455_016061

Neo: -

Age: -

Region-specific R2: 2.881

Region-enriched R2: 1.672/0.00180

3.59 - - 0.707 0.942 0.990 0.951 Mlig455_016061 {REF} {Length: 649} {RNA1509_58232} {RNA1310_60107.1, RNA1509_58232} {RNA1509_58232, RNA815_31573}
21. MligTC455_41130 1186 24.72 Mlig455_000166, Mlig455_000179, Mlig455_067712

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.626

Region-enriched R2: 4.906/0.00009

Regeneration-downregulated R3: -5.200

Regeneration-depleted R3: -5.200

3.584 0.738 - - 0.946 0.930 0.970

Mlig455_000166 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_000179 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_067712 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}
22. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

3.579 - 0.928 - 0.768 0.917 0.966 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
23. MligTC455_16749 454 9.45 Mlig455_001550, Mlig455_046548

Neo: -

Age: logFC(26M/2M)=0.515

Region-specific R2: 4.360

Region-enriched R2: 3.409/0.00015

TRAF4 3.579 - 0.843 - 0.950 0.819 0.967

Mlig455_001550 {REF} {Length: 4563} {Pfam: TRAF-type zinc finger [PF02176.20, score=81.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.3]; Seven in absentia protein family [PF03145.18, score=27.2]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.0]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.9]; zinc finger of C3HC4-type, RING [PF15227.8, score=20.4]; zf-RING of BARD1-type protein [PF14835.8, score=20.3]; Ring finger domain [PF13639.8, score=19.5]} {Human: ENSG00000076604, TRAF4, TNF receptor associated factor 4, [Score=237, Expect=4e-72]} {Mouse: ENSMUSG00000017386, Traf4, TNF receptor associated factor 4, [Score=241, Expect=7e-74]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=164, Expect=1e-44]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [RH, Score=276, Expect=1e-87]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_20900} {RNA1310_14813, RNA1509_20900} {RNA1509_20900, RNA815_2335.1}

Mlig455_046548 {REF} {Length: 3881} {Pfam: TRAF-type zinc finger [PF02176.20, score=81.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.3]; Seven in absentia protein family [PF03145.18, score=27.2]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=23.0]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=22.9]; zinc finger of C3HC4-type, RING [PF15227.8, score=20.4]; zf-RING of BARD1-type protein [PF14835.8, score=20.3]; Ring finger domain [PF13639.8, score=19.5]} {Human: ENSG00000076604, TRAF4, TNF receptor associated factor 4, [Score=236, Expect=1e-71]} {Mouse: ENSMUSG00000017386, Traf4, TNF receptor associated factor 4, [Score=240, Expect=3e-73]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=164, Expect=9e-45]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [RH, Score=275, Expect=6e-87]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_20900} {RNA1310_14813} {RNA815_2335.1}
24. MligTC455_45665 1443 30.07 Mlig455_011779

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.663

Region-enriched R2: 1.647/0.04427

Regeneration-depleted R6: -3.147
Regeneration-depleted BL: -2.857

3.575 - 0.876 - 0.958 0.781 0.960 Mlig455_011779 {REF} {Length: 735} {TRANSSPLICED} {RNA1509_33726} {RNA1310_46610, RNA1509_33726} {RNA1509_33726, RNA815_23273}
25. MligTC455_19325 1452 30.24 Mlig455_036471, Mlig455_056256

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.575

Region-enriched R2: 2.298/0.00464
Region-enriched R8: 2.134/0.01396

3.573 - 0.951 - 0.930 0.864 0.828

Mlig455_036471 {REF} {Length: 598} {RNA1509_40294} {RNA1310_65876} {RNA815_35457}

Mlig455_056256 {REF} {Length: 599} {RNA1509_40294} {RNA1310_65876, RNA1509_40294} {RNA1509_40294, RNA815_35457}
26. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

3.557 - 0.707 - 0.922 0.939 0.989 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
27. MligTC455_53844 1403 29.24 Mlig455_051626

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

3.557 - 0.923 - 0.721 0.948 0.965 Mlig455_051626 {REF} {Length: 1671} {RNA1509_15580} {RNA1310_24090} {RNA815_10676.2}
28. MligTC455_53413 249 5.2 Mlig455_035022

Neo: -

Age: -

Region-specific R2: 4.451

Region-enriched R2: 3.023/0.00460

RP1 3.556 - - 0.723 0.967 0.889 0.977 Mlig455_035022 {REF} {Length: 5065} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_57003} {RNA1310_2710} {RNA815_13802.1}
29. MligTC455_29929 164 3.41 Mlig455_030237, Mlig455_068015

Neo: -

Age: -

Region-enriched R2: 4.901/0.00350

SIX6 3.541 - - 0.972 0.727 0.872 0.970

Mlig455_030237 {REF} {Length: 2545} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.1]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=8e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=6e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=9e-93]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=2e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}

Mlig455_068015 {REF} {Length: 2713} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.2]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=7e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=5e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=1e-92]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=1e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=1e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}
30. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

3.54 - - 0.914 0.754 0.905 0.967

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
31. MligTC455_19876 135 2.82 Mlig455_024520, Mlig455_024523

Neo: -

Age: -

3.539 - 0.826 - 0.935 0.819 0.959

Mlig455_024520 {REF} {Length: 2352} {Pfam: CD20-like family [PF04103.17, score=40.9]} {Mouse: ENSMUSG00000048004, Tmem196, transmembrane protein 196, [Score=63.5, Expect=2e-12]} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=184, Expect=5e-59]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}

Mlig455_024523 {REF} {Length: 2311} {Smed: dd_Smed_v6_14043_0_1, dd_Smed_v6_14043_0_1, [Score=153, Expect=3e-47]} {RNA1509_25506} {RNA1310_9338} {RNA815_23744}
32. MligTC455_46698 2235 46.56 Mlig455_009652

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.372/0.00045
Region-enriched R7: 2.057/0.00055

Regeneration-depleted TP: -3.177
Regeneration-depleted BL: -2.998

3.536 - 0.747 - 0.900 0.968 0.921 Mlig455_009652 {REF} {Length: 763} {Pfam: WD repeat binding protein EZH2 [PF11616.10, score=33.2]; NOPS (NUC059) domain [PF08075.13, score=29.1]} {RNA1509_45891} {RNA1310_92759} {RNA815_24028}
33. MligTC455_47806 2724 56.76 Mlig455_033677

Neo: -

Age: -

Region-specific R2: 3.773

Region-enriched R2: 2.504/0.00005

3.533 - - 0.755 0.936 0.962 0.880 Mlig455_033677 {REF} {Length: 1836} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1310_30659.1, RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504} {RNA1509_1605, RNA1509_16422, RNA1509_33244, RNA1509_46504, RNA815_13807}
34. MligTC455_46067 548 11.42 Mlig455_054518, Mlig455_055436, Mlig455_055448

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.305/0.04262

GRIK3, GRIK4 3.52 - - 0.900 0.757 0.880 0.983

Mlig455_054518 {REF} {Length: 4725} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=91.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.2]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=222, Expect=5e-60]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=222, Expect=6e-60]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=218, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=3e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=215, Expect=1e-57]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=9e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=213, Expect=9e-57]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=224, Expect=2e-60]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=224, Expect=9e-61]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=220, Expect=2e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=215, Expect=1e-57]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=296, Expect=6e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=312, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_14215, RNA1509_40992} {RNA1310_5620.1, RNA1509_14215, RNA1509_40992} {RNA1509_14215, RNA1509_40992, RNA815_1965}

Mlig455_055436 {REF} {Length: 4732} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=6e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=7e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=7e-59]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=9e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=211, Expect=2e-56]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=226, Expect=3e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_40992} {RNA1310_5620.1} {RNA815_1965}

Mlig455_055448 {REF} {Length: 4726} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=9e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=9e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=8e-59]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=217, Expect=2e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=7e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=6e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=225, Expect=4e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=217, Expect=9e-59]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=5e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_32892, RNA1509_40992} {RNA1310_5620.1, RNA1509_32892} {RNA1509_32892, RNA815_1965}
35. MligTC455_37720 156 3.25 Mlig455_027725, Mlig455_027921, Mlig455_027931

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.630/0.03113

TRPV6 3.513 0.826 - - 0.825 0.898 0.964

Mlig455_027725 {REF} {Length: 5690} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.7]; Ion transport protein [PF00520.33, score=39.6]; Ankyrin repeat [PF13606.8, score=33.0]; Ankyrin repeats (many copies) [PF13857.8, score=30.8]; Ankyrin repeat [PF00023.32, score=29.7]; Polycystin cation channel [PF08016.14, score=27.5]; Ankyrin repeats (many copies) [PF13637.8, score=21.3]} {Human: ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=207, Expect=4e-55]; ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=206, Expect=4e-55]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [Score=206, Expect=1e-54]} {Dmel: FBgn0086693, iav, inactive, [RH, Score=568, Expect=0.0]} {Celegans: WBGene00003889, osm-9, Olfactory channel, [RH, Score=489, Expect=8e-156]} {Smed: dd_Smed_v6_28914_0_1, dd_Smed_v6_28914_0_1, [Score=492, Expect=6e-158]} {RNA1509_36869} {RNA1310_5278, RNA1509_36869} {RNA1509_36869, RNA815_5723}

Mlig455_027921 {REF} {Length: 8298} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.7]; Ion transport protein [PF00520.33, score=39.2]; Ankyrin repeat [PF13606.8, score=33.0]; Ankyrin repeats (many copies) [PF13857.8, score=30.8]; Ankyrin repeat [PF00023.32, score=29.8]; Polycystin cation channel [PF08016.14, score=27.1]; Ankyrin repeats (many copies) [PF13637.8, score=21.3]} {Human: ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=207, Expect=4e-55]; ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=206, Expect=5e-55]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [Score=206, Expect=9e-55]} {Dmel: FBgn0086693, iav, inactive, [RH, Score=566, Expect=0.0]} {Celegans: WBGene00003889, osm-9, Olfactory channel, [RH, Score=488, Expect=1e-155]} {Smed: dd_Smed_v6_28914_0_1, dd_Smed_v6_28914_0_1, [Score=491, Expect=1e-157]} {RNA1509_36869} {RNA1310_5278} {RNA815_5723}

Mlig455_027931 {REF} {Length: 6147} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.7]; Ion transport protein [PF00520.33, score=40.0]; Ankyrin repeat [PF13606.8, score=34.3]; Ankyrin repeats (many copies) [PF13857.8, score=31.5]; Ankyrin repeat [PF00023.32, score=30.2]; Polycystin cation channel [PF08016.14, score=27.8]; Ankyrin repeats (many copies) [PF13637.8, score=21.7]} {Human: ENSG00000276971, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=208, Expect=7e-56]; ENSG00000165125, TRPV6, transient receptor potential cation channel subfamily V member 6, [RH, Score=207, Expect=1e-55]} {Mouse: ENSMUSG00000029868, Trpv6, transient receptor potential cation channel, subfamily V, member 6, [Score=206, Expect=3e-55]} {Dmel: FBgn0086693, iav, inactive, [RH, Score=567, Expect=0.0]} {Celegans: WBGene00003889, osm-9, Olfactory channel, [RH, Score=488, Expect=5e-157]} {Smed: dd_Smed_v6_28914_0_1, dd_Smed_v6_28914_0_1, [Score=490, Expect=4e-159]} {RNA1509_36869} {RNA1310_5278} {RNA815_5723}
36. MligTC455_44328 858 17.88 Mlig455_026172

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.714

Region-enriched R2: 4.385/0.00000

3.512 0.796 - - 0.846 0.910 0.960 Mlig455_026172 {REF} {Length: 661} {RNA1509_32102, RNA1509_34635} {RNA1310_60068, RNA1509_32102, RNA1509_34635} {RNA1509_32102, RNA1509_34635, RNA815_37486}
37. MligTC455_46394 8810 183.54 Mlig455_054818, Mlig455_054826

Neo: -

Age: -

Region-specific R2: 1.771

Region-enriched R2: 1.255/0.00038

PKD2 3.507 - 0.707 - 0.845 0.977 0.978

Mlig455_054818 {REF} {Length: 2992} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=747, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=380, Expect=6e-120]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [Score=733, Expect=0.0]} {RNA1509_1615} {RNA1310_21296.2, RNA1509_1615} {RNA1509_1615, RNA815_3158.1}

Mlig455_054826 {REF} {Length: 3118} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.4]; EF hand [PF00036.34, score=32.6]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=2e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=1e-122]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
38. MligTC455_49285 164 3.41 Mlig455_004486, Mlig455_037380

Neo: -

Age: -

Region-specific R2: 6.095

Region-enriched R2: 5.942/0.00244

LEF1 3.506 0.935 - - 0.796 0.788 0.987

Mlig455_004486 {REF} {Length: 3612} {Pfam: HMG (high mobility group) box [PF00505.21, score=30.1]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [Score=105, Expect=2e-24]; ENSG00000081059, TCF7, transcription factor 7, [Score=103, Expect=3e-25]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [Score=100, Expect=2e-22]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [Score=105, Expect=6e-25]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [Score=101, Expect=8e-24]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [Score=100, Expect=1e-22]} {Dmel: FBgn0085432, pan, pangolin, [Score=103, Expect=1e-23]} {Celegans: WBGene00004077, pop-1, [Score=82.0, Expect=8e-17]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [Score=114, Expect=3e-29]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}

Mlig455_037380 {REF} {Length: 3365} {Pfam: HMG (high mobility group) box [PF00505.21, score=78.7]; HMG-box domain [PF09011.12, score=32.5]} {Human: ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=156, Expect=1e-43]; ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=154, Expect=7e-41]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=154, Expect=3e-44]; ENSG00000148737, TCF7L2, transcription factor 7 like 2, [RH, Score=150, Expect=6e-44]} {Mouse: ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=157, Expect=9e-44]; ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=156, Expect=1e-41]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=153, Expect=1e-42]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=155, Expect=1e-40]} {Celegans: WBGene00004077, pop-1, [Score=104, Expect=4e-24]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=165, Expect=2e-48]} {RNA1509_13914} {RNA1310_16097} {RNA815_47141}
39. MligTC455_40270 49 1.03 Mlig455_002977

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.640/0.00158

AGAP1 3.496 0.952 - - 0.948 0.856 0.740 Mlig455_002977 {REF} {Length: 2591} {Pfam: Ras family [PF00071.24, score=40.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.9]} {Human: ENSG00000157985, AGAP1, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, [Score=253, Expect=3e-81]; ENSG00000133612, AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=243, Expect=2e-77]} {Mouse: ENSMUSG00000055013, Agap1, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, [Score=253, Expect=2e-77]; ENSMUSG00000023353, Agap3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, [Score=243, Expect=2e-77]} {Dmel: FBgn0028509, CenG1A, Centaurin gamma 1A, [Score=251, Expect=7e-76]} {Celegans: WBGene00000566, cnt-2, Arf-GAP with ANK repeat and PH domain-containing protein cnt-2, [Score=205, Expect=2e-59]} {Smed: dd_Smed_v6_4301_0_1, dd_Smed_v6_4301_0_1, [Score=232, Expect=7e-73]} {RNA1509_22773} {RNA1310_2370} {RNA815_11138}
40. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 3.484 - - 0.765 0.860 0.897 0.962 Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
41. MligTC455_20686 474 9.88 Mlig455_041407, Mlig455_041444, Mlig455_060901

Neo: -

Age: -

Region-enriched R2: 1.932/0.02120

3.483 - 0.896 - 0.745 0.881 0.961

Mlig455_041407 {REF} {Length: 1387} {Smed: dd_Smed_v6_12479_0_1, dd_Smed_v6_12479_0_1, [RH, Score=73.6, Expect=3e-17]} {RNA1509_36978} {RNA1310_41260} {RNA815_26996}

Mlig455_041444 {REF} {Length: 935} {Smed: dd_Smed_v6_12479_0_1, dd_Smed_v6_12479_0_1, [RH, Score=73.6, Expect=4e-17]} {RNA1509_36978} {RNA1310_41260} {RNA815_47140}

Mlig455_060901 {REF} {Length: 2316} {Smed: dd_Smed_v6_12479_0_1, dd_Smed_v6_12479_0_1, [RH, Score=73.6, Expect=3e-17]} {RNA1509_36978} {RNA1310_41260} {RNA815_47140}
42. MligTC455_43173 392 8.16 Mlig455_037383

Neo: -

Age: Up-Down-Down

Regeneration-downregulated TP: -5.031

Regeneration-depleted TP: -5.031

C2orf16 3.482 - 0.754 - 0.800 0.952 0.976 Mlig455_037383 {REF} {Length: 2450} {Pfam: Cornifin (SPRR) family [PF02389.17, score=23.4]} {Human: ENSG00000221843, C2orf16, chromosome 2 open reading frame 16, [Score=80.1, Expect=7e-15]} {RNA1509_52401} {RNA1310_14622.1} {RNA815_17994}
43. MligTC455_27801 113 2.36 Mlig455_033476

Neo: -

Age: -

PLCH2 3.48 - - 0.934 0.755 0.836 0.955 Mlig455_033476 {REF} {Length: 8788} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=200.3]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=106.2]; RasGEF domain [PF00617.21, score=54.0]; Ras association (RalGDS/AF-6) domain [PF00788.25, score=39.7]; C2 domain [PF00168.32, score=29.3]} {Human: ENSG00000149527, PLCH2, phospholipase C eta 2, [Score=326, Expect=4e-90]; ENSG00000276429, PLCH2, phospholipase C eta 2, [Score=326, Expect=4e-90]; ENSG00000101333, PLCB4, phospholipase C beta 4, [Score=325, Expect=1e-90]} {Mouse: ENSMUSG00000024998, Plce1, phospholipase C, epsilon 1, [RH, Score=282, Expect=1e-75]} {Dmel: FBgn0003416, sl, small wing, [Score=164, Expect=3e-40]} {Celegans: WBGene00004036, plc-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, [Score=432, Expect=6e-123]} {Smed: dd_Smed_v6_9716_1_1, dd_Smed_v6_9716_1_1, [Score=752, Expect=0.0]} {RNA1509_26054} {RNA1310_1143.2} {RNA815_10233}
44. MligTC455_49877 188 3.91 Mlig455_027465

Neo: -

Age: -

Region-enriched R2: 3.005/0.04141

AC254952.1 3.474 - 0.794 - 0.913 0.799 0.968 Mlig455_027465 {REF} {Length: 2059} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=89.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.0]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=6e-38]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=144, Expect=9e-38]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=141, Expect=2e-36]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=1e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=6e-37]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=139, Expect=5e-36]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=134, Expect=2e-34]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=132, Expect=4e-33]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=126, Expect=6e-32]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=131, Expect=2e-33]} {RNA1310_26175} {RNA815_7952}
45. MligTC455_12180 107 2.23 Mlig455_038554, Mlig455_052202, Mlig455_053449

Neo: -

Age: logFC(26M/2M)=-0.655

Region-enriched R2: 5.717/0.01573

CNGA3 3.469 0.921 - - 0.768 0.803 0.977

Mlig455_038554 {REF} {Length: 2866} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=75.9]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.6]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=607, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=669, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_052202 {REF} {Length: 3203} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=76.1]; Cyclic nucleotide-binding domain [PF00027.31, score=69.1]; Ion transport protein [PF00520.33, score=68.2]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [RH, Score=644, Expect=0.0]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [RH, Score=605, Expect=0.0]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [RH, Score=563, Expect=0.0]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [RH, Score=667, Expect=0.0]} {RNA1310_22950} {RNA815_16119}

Mlig455_053449 {REF} {Length: 991} {Pfam: C-terminal leucine zipper domain of cyclic nucleotide-gated channels [PF16526.7, score=79.9]; Cyclic nucleotide-binding domain [PF00027.31, score=29.1]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [Score=171, Expect=7e-50]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [Score=161, Expect=2e-46]; ENSMUSG00000067220, Cnga1, cyclic nucleotide gated channel alpha 1, [Score=155, Expect=4e-44]} {Dmel: FBgn0261612, CngA, Cyclic nucleotide-gated ion channel subunit A, [Score=148, Expect=1e-41]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=149, Expect=3e-42]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [Score=155, Expect=8e-45]} {RNA1310_61700} {RNA815_16119}
46. MligTC455_35410 528 11 Mlig455_064178

Neo: -

Age: Down-Down-Down

Region-enriched R2: 2.241/0.03122

PPP3CA 3.462 0.834 - - 0.958 0.771 0.899 Mlig455_064178 {REF} {Length: 4178} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=129.2]} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=701, Expect=0.0]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=690, Expect=0.0]; ENSG00000120910, PPP3CC, protein phosphatase 3 catalytic subunit gamma, [Score=673, Expect=0.0]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=703, Expect=0.0]; ENSMUSG00000021816, Ppp3cb, protein phosphatase 3, catalytic subunit, beta isoform, [Score=690, Expect=0.0]} {Dmel: FBgn0267912, CanA-14F, Calcineurin A at 14F, [Score=697, Expect=0.0]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [Score=646, Expect=0.0]} {Smed: dd_Smed_v6_5378_0_1, dd_Smed_v6_5378_0_1, [Score=523, Expect=0.0]} {RNA1509_25279} {RNA1310_17931} {RNA815_6996}
47. MligTC455_41382 65 1.35 Mlig455_022554

Neo: -

Age: -

Region-enriched R2: 5.596/0.01432

3.451 - - 0.940 0.774 0.767 0.970 Mlig455_022554 {REF} {Length: 503} {Pfam: Pancreatic hormone peptide [PF00159.20, score=18.9]} {RNA1310_81495} {RNA815_42745}
48. MligTC455_32446 142 2.95 Mlig455_042069

Neo: -

Age: Up-Down-Down

TRPA1 3.448 - - 0.878 0.727 0.889 0.954 Mlig455_042069 {REF} {Length: 6835} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=191.2]; Ankyrin repeats (many copies) [PF13637.8, score=164.6]; Ankyrin repeats (many copies) [PF13857.8, score=152.4]; Ankyrin repeat [PF13606.8, score=136.2]; Ankyrin repeat [PF00023.32, score=129.7]; Ion transport protein [PF00520.33, score=47.4]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=176, Expect=1e-44]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=286, Expect=4e-81]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=173, Expect=6e-44]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=450, Expect=2e-140]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=627, Expect=0.0]} {RNA1509_32186} {RNA1310_1780} {RNA815_450.1}
49. MligTC455_42994 1521 31.7 Mlig455_035840

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

Region-enriched R2: 1.854/0.00052

3.446 - 0.745 - 0.756 0.957 0.988 Mlig455_035840 {REF} {Length: 1436} {RNA1509_29485, RNA1509_42231} {RNA1310_26640, RNA1509_29485, RNA1509_42231} {RNA1509_29485, RNA1509_42231, RNA815_37260}
50. MligTC455_30159 107 2.22 Mlig455_008465, Mlig455_009916

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.961/0.00498

TCF7L1 3.443 - - 0.963 0.707 0.859 0.914

Mlig455_008465 {REF} {Length: 2454} {Pfam: HMG (high mobility group) box [PF00505.21, score=81.3]; HMG-box domain [PF09011.12, score=34.6]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=7e-43]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=3e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=156, Expect=8e-42]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=161, Expect=4e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=4e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=6e-43]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=157, Expect=4e-41]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=2e-48]} {RNA1310_11181} {RNA815_36690}

Mlig455_009916 {REF} {Length: 2137} {Pfam: HMG (high mobility group) box [PF00505.21, score=81.4]; HMG-box domain [PF09011.12, score=34.7]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=161, Expect=4e-43]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=2e-43]; ENSG00000081059, TCF7, transcription factor 7, [RH, Score=157, Expect=5e-42]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=162, Expect=2e-43]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=159, Expect=3e-44]; ENSMUSG00000000782, Tcf7, transcription factor 7, T cell specific, [RH, Score=155, Expect=4e-43]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=157, Expect=3e-41]} {Celegans: WBGene00004077, pop-1, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_34144_0_1, dd_Smed_v6_34144_0_1, [RH, Score=166, Expect=1e-48]} {RNA1310_11181} {RNA815_36690}
51. MligTC455_39748 17060 355.41 Mlig455_068905

Neo: -

Age: -

Region-enriched R7: 2.255/0.00030

Regeneration-downregulated BL: -3.088

Regeneration-depleted BL: -3.088

3.435 - - 0.708 0.956 0.908 0.863 Mlig455_068905 {REF} {Length: 1123} {Celegans: WBGene00001446, flp-3, FMRFamide-like neuropeptides 3 SPLGTMRF-amide TPLGTMRF-amide SAEPFGTMRF-amide NPENDTPFGTMRF-amide ASEDALFGTMRF-amide EAEEPLGTMRF-amide SADDSAPFGTMRF-amide NPLGTMRF-amide, [Score=52.4, Expect=4e-08]} {Smed: dd_Smed_v6_1902_0_1, dd_Smed_v6_1902_0_1, [RH, Score=47.4, Expect=2e-07]} {RNA1509_13775, RNA1509_15073, RNA1509_16548, RNA1509_23529, RNA1509_549} {RNA1310_55834.1, RNA1509_13775, RNA1509_15073, RNA1509_16548, RNA1509_23529, RNA1509_549} {RNA1509_13775, RNA1509_15073, RNA1509_16548, RNA1509_23529, RNA1509_549, RNA815_29732}
52. MligTC455_25914 4684 97.58 Mlig455_004975

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.418

Region-enriched R2: 1.471/0.00163

Regeneration-downregulated BL: -1.843

Regeneration-depleted BL: -1.843

3.434 0.731 - - 0.960 0.822 0.921 Mlig455_004975 {REF} {Length: 5220} {RNA1509_1158, RNA1509_11723} {RNA1310_4621.1, RNA1509_11723} {RNA1509_11723, RNA815_1336.1}
53. MligTC455_07624 777 16.19 Mlig455_062715

Neo: -

Age: Up-Down-Up

STOM 3.431 - - 0.963 0.816 0.894 0.758 Mlig455_062715 {REF} {Length: 3417} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=112.9]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=365, Expect=3e-126]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=362, Expect=2e-125]} {Dmel: FBgn0260657, CG42540, [RH, Score=384, Expect=9e-131]} {Celegans: WBGene00006064, sto-2, Stomatin-2, [RH, Score=393, Expect=2e-136]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=379, Expect=3e-132]} {RNA1509_47159, RNA1509_9137} {RNA1310_11482.1, RNA1509_47159, RNA1509_9137} {RNA1509_47159, RNA1509_9137, RNA815_6842}
54. MligTC455_12032 92 1.91 Mlig455_044477

Neo: -

Age: -

KCNIP1 3.43 0.979 - - 0.849 0.876 0.726 Mlig455_044477 {REF} {Length: 1077} {Pfam: EF hand [PF00036.34, score=60.1]; EF-hand domain [PF13405.8, score=57.2]; EF-hand domain pair [PF13499.8, score=54.7]; EF-hand domain pair [PF13833.8, score=47.2]; EF hand [PF13202.8, score=43.0]} {Human: ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=169, Expect=9e-52]; ENSG00000120049, KCNIP2, potassium voltage-gated channel interacting protein 2, [Score=164, Expect=7e-49]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=170, Expect=2e-52]} {Dmel: FBgn0039380, CG5890, [Score=150, Expect=5e-45]} {Celegans: WBGene00008998, ncs-4, Neuronal Calcium Sensor family, [RH, Score=121, Expect=1e-33]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=163, Expect=6e-50]} {RNA1310_40826} {RNA815_29104}
55. MligTC455_37315 84 1.76 Mlig455_048842

Neo: -

Age: -

CALM2 3.423 - - 0.853 0.707 0.896 0.967 Mlig455_048842 {REF} {Length: 1287} {Pfam: EF-hand domain pair [PF13499.8, score=22.7]; EF-hand domain [PF14658.8, score=19.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=68.9, Expect=6e-14]; ENSG00000198668, CALM1, calmodulin 1, [Score=68.2, Expect=4e-14]; ENSG00000160014, CALM3, calmodulin 3, [Score=66.6, Expect=2e-13]; ENSG00000178363, CALML3, calmodulin like 3, [Score=65.5, Expect=4e-13]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=67.0, Expect=2e-13]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=66.6, Expect=1e-13]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=66.6, Expect=1e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=68.6, Expect=1e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=68.6, Expect=1e-14]} {Smed: dd_Smed_v6_5491_0_1, dd_Smed_v6_5491_0_1, [Score=110, Expect=3e-30]} {RNA1310_33365} {RNA815_27013}
56. MligTC455_25915 4499 93.72 Mlig455_005297

Neo: -

Age: -

Region-enriched R2: 1.495/0.00336

Regeneration-downregulated BL: -1.833

Regeneration-depleted BL: -1.833

CPE 3.411 0.725 - - 0.957 0.819 0.910 Mlig455_005297 {REF} {Length: 3239} {Pfam: Zinc carboxypeptidase [PF00246.26, score=188.0]; Carboxypeptidase regulatory-like domain [PF13620.8, score=23.3]} {Human: ENSG00000109472, CPE, carboxypeptidase E, [Score=322, Expect=8e-105]} {Mouse: ENSMUSG00000037852, Cpe, carboxypeptidase E, [Score=318, Expect=1e-103]} {Dmel: FBgn0004648, svr, silver, [Score=225, Expect=2e-68]} {Celegans: WBGene00001189, egl-21, Carboxypeptidase E, [RH, Score=333, Expect=5e-110]} {Smed: dd_Smed_v6_3059_0_1, dd_Smed_v6_3059_0_1, [RH, Score=384, Expect=7e-130]} {RNA1509_1158, RNA1509_34474, RNA1509_41810, RNA1509_58201, RNA1509_8908} {RNA1310_4621.1, RNA1509_1158, RNA1509_34474, RNA1509_41810, RNA1509_58201, RNA1509_8908} {RNA1509_1158, RNA1509_34474, RNA1509_41810, RNA1509_58201, RNA1509_8908, RNA815_1336.1}
57. MligTC455_39957 170 3.54 Mlig455_039809

Neo: -

Age: -

Region-specific R2: 4.733

Region-enriched R2: 5.232/0.00000

ADGB 3.389 0.721 - - 0.763 0.939 0.966 Mlig455_039809 {REF} {Length: 7010} {tRNA: Ile(TAT),pseudo, score=33.4} {Pfam: Calpain family cysteine protease [PF00648.23, score=34.1]} {Human: ENSG00000118492, ADGB, androglobin, [Score=403, Expect=6e-115]} {Mouse: ENSMUSG00000050994, Adgb, androglobin, [Score=252, Expect=4e-67]} {Celegans: WBGene00000543, clp-2, CaLPain family, [Score=73.2, Expect=1e-12]} {Smed: dd_Smed_v6_10677_0_1, dd_Smed_v6_10677_0_1, [Score=253, Expect=8e-68]} {RNA1509_15950, RNA1509_59203} {RNA1310_4821, RNA1509_59203} {RNA1509_59203, RNA815_12506}
58. MligTC455_25589 1419 29.55 Mlig455_029945

Neo: -

Age: -

Region-enriched R2: 2.293/0.00000

Regeneration-downregulated BL: -3.516

Regeneration-depleted BL: -3.516

3.382 - 0.940 - 0.787 0.954 0.701 Mlig455_029945 {REF} {Length: 1261} {Pfam: Helix-turn-helix domain [PF12645.9, score=19.8]; Domain of unknown function (DUF1848) [PF08902.13, score=19.3]} {RNA1509_17753} {RNA1310_70608, RNA1509_17753} {RNA1509_17753, RNA815_1498.1}
59. MligTC455_45622 647 13.48 Mlig455_069391

Neo: -

Age: -

Region-specific R2: 5.132

Region-enriched R2: 3.915/0.00000

Regeneration-downregulated R2: -2.412

Regeneration-depleted R2: -2.412

3.362 - 0.702 - 0.827 0.844 0.989 Mlig455_069391 {REF} {Length: 971} {Smed: dd_Smed_v6_2575_0_1, dd_Smed_v6_2575_0_1, [Score=45.1, Expect=4e-07]} {RNA1509_31982} {RNA1310_46295} {RNA815_23543}
60. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

3.361 0.797 - - 0.705 0.877 0.982

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
61. MligTC455_40874 65 1.34 Mlig455_051048

Neo: -

Age: -

ASIC5 3.355 - - 0.808 0.863 0.717 0.967 Mlig455_051048 {REF} {Length: 2313} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=194.4]} {Human: ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=54.3, Expect=4e-07]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=64.7, Expect=1e-10]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [RH, Score=491, Expect=1e-167]} {RNA1509_56048} {RNA1310_34335} {RNA815_62672}
62. MligTC455_53842 1222 25.46 Mlig455_023890

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.345

Region-enriched R2: 1.546/0.01667

3.349 - 0.739 - 0.787 0.854 0.969 Mlig455_023890 {REF} {Length: 1336} {RNA1509_15580} {RNA1310_22487.1} {RNA815_10676.1}
63. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 3.348 - 0.718 - 0.787 0.963 0.880

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
64. MligTC455_43557 362 7.55 Mlig455_059172, Mlig455_065527

Neo: -

Age: Down-Down-Up

Region-specific R2: 6.284

Region-enriched R2: 5.832/0.00001

ANKRD63 3.344 - 0.743 - 0.732 0.891 0.978

Mlig455_059172 {REF} {Length: 1739} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.2]; Ankyrin repeats (many copies) [PF13637.8, score=42.6]; Ankyrin repeat [PF13606.8, score=27.6]; Ankyrin repeats (many copies) [PF13857.8, score=27.1]; Ankyrin repeat [PF00023.32, score=25.9]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=67.4, Expect=7e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=49.3, Expect=7e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=49.3, Expect=4e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=81.3, Expect=1e-16]} {RNA1310_44826} {RNA815_62096}

Mlig455_065527 {REF} {Length: 2998} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=52.3]; Ankyrin repeats (many copies) [PF13637.8, score=42.0]; Ankyrin repeats (many copies) [PF13857.8, score=26.7]; Ankyrin repeat [PF00023.32, score=26.0]; Ankyrin repeat [PF13606.8, score=22.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=68.2, Expect=6e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=50.1, Expect=5e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=50.4, Expect=2e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=80.9, Expect=2e-16]} {RNA1509_30872} {RNA1310_44826} {RNA815_62096}
65. MligTC455_19079 218 4.54 Mlig455_008746, Mlig455_008760

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.705

Region-enriched R2: 6.864/0.00152

3.341 0.713 - - 0.793 0.867 0.968

Mlig455_008746 {REF} {Length: 652} {RNA1310_75395.1} {RNA815_42524}

Mlig455_008760 {REF} {Length: 1051} {RNA1310_75395.1} {RNA815_42524}
66. MligTC455_53233 1483 30.9 Mlig455_037746, Mlig455_069921

Neo: -

Age: -

Region-specific R2: 7.323

Region-enriched R2: 7.524/0.00000

Regeneration-downregulated R2: -3.635

Regeneration-depleted R2: -3.635

PKD2 3.322 - - 0.789 0.727 0.821 0.985

Mlig455_037746 {REF} {Length: 3024} {Pfam: Polycystin cation channel [PF08016.14, score=468.5]; Ion transport protein [PF00520.33, score=85.9]; EF-hand domain pair [PF13499.8, score=21.3]; EF hand [PF00036.34, score=21.2]; EF-hand domain [PF13405.8, score=18.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=708, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=699, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=306, Expect=2e-90]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=379, Expect=1e-119]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=719, Expect=0.0]} {RNA1509_30624, RNA1509_6992} {RNA1310_6033, RNA1509_30624} {RNA1509_30624, RNA815_1577.1}

Mlig455_069921 {REF} {Length: 3030} {Pfam: Polycystin cation channel [PF08016.14, score=467.0]; Ion transport protein [PF00520.33, score=85.5]; EF hand [PF00036.34, score=21.3]; EF-hand domain pair [PF13499.8, score=21.3]; EF-hand domain [PF13405.8, score=18.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=707, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=699, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=304, Expect=8e-90]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=377, Expect=3e-119]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=716, Expect=0.0]} {RNA1509_6992} {RNA1310_6033, RNA1509_6992} {RNA1509_6992, RNA815_1577.1}
67. MligTC455_25072 4443 92.56 Mlig455_015899

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.175

Region-enriched R2: 4.389/0.00000

PI16 3.318 - - 0.750 0.803 0.797 0.968 Mlig455_015899 {REF} {Length: 2017} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=71.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=112, Expect=1e-26]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [RH, Score=115, Expect=5e-28]} {Dmel: FBgn0038126, CG8483, [Score=95.5, Expect=2e-21]} {Celegans: WBGene00011462, vap-2, Venom-Allergen-like Protein, [RH, Score=85.5, Expect=5e-18]} {Smed: dd_Smed_v6_2512_0_1, dd_Smed_v6_2512_0_1, [Score=140, Expect=2e-39]} {RNA1509_5027} {RNA1310_1356.1} {RNA815_4508}
68. MligTC455_28543 223 4.64 Mlig455_057913

Neo: -

Age: Down-Up-Down

TTLL6 3.307 - - 0.866 0.767 0.720 0.954 Mlig455_057913 {REF} {Length: 4159} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=268.0]} {Human: ENSG00000170703, TTLL6, tubulin tyrosine ligase like 6, [RH, Score=511, Expect=3e-167]} {Mouse: ENSMUSG00000045467, Ttll13, tubulin tyrosine ligase-like family, member 13, [Score=558, Expect=0.0]} {Dmel: FBgn0039501, CG5987, [RH, Score=453, Expect=2e-147]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=220, Expect=6e-61]} {Smed: dd_Smed_v6_8131_0_1, dd_Smed_v6_8131_0_1, [Score=669, Expect=0.0]} {RNA1509_19350} {RNA1310_5550.1} {RNA815_3974}
69. MligTC455_13102 65 1.35 Mlig455_056246

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.206/0.00027

NWD2 3.3 0.838 - - 0.720 0.786 0.956 Mlig455_056246 {REF} {Length: 8104} {Pfam: NACHT domain [PF05729.14, score=51.2]; AAA ATPase domain [PF13191.8, score=36.8]; Domain of unknown function (DUF4062) [PF13271.8, score=36.5]; ATPase domain predominantly from Archaea [PF01637.20, score=23.7]; AAA domain [PF13401.8, score=20.6]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=451, Expect=2e-130]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [RH, Score=436, Expect=2e-125]} {Dmel: FBgn0038397, CG10185, [RH, Score=980, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [RH, Score=925, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=344, Expect=9e-96]} {RNA1509_20730} {RNA1310_1147} {RNA815_11922}
70. MligTC455_48609 3538 73.7 Mlig455_037431, Mlig455_037454, Mlig455_037501

Neo: -

Age: -

Region-specific R2: 3.134

Region-enriched R2: 1.985/0.00000

Regeneration-downregulated BL: -2.003

Regeneration-depleted BL: -2.003

CAPN5 3.3 - 0.752 - 0.762 0.966 0.820

Mlig455_037431 {REF} {Length: 2455} {Pfam: Calpain family cysteine protease [PF00648.23, score=124.0]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=103, Expect=1e-22]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=2e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=103, Expect=5e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}

Mlig455_037454 {REF} {Length: 1043} {RNA1509_15549} {RNA1310_57168} {RNA815_30048}

Mlig455_037501 {REF} {Length: 2687} {Pfam: Calpain family cysteine protease [PF00648.23, score=123.7]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=105, Expect=5e-23]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=3e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=104, Expect=4e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}
71. MligTC455_46451 229 4.76 Mlig455_017183

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.510

Region-enriched R2: 5.394/0.00018

Regeneration-downregulated R2: -2.986

Regeneration-depleted R2: -2.986

3.294 0.847 - - 0.708 0.781 0.958 Mlig455_017183 {REF} {Length: 657} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.6]} {RNA1310_62963} {RNA815_31352}
72. MligTC455_25112 611 12.74 Mlig455_020700

Neo: -

Age: Down-Down-Up

Region-enriched R7: 1.981/0.01296

3.285 0.774 - - 0.718 0.962 0.831 Mlig455_020700 {REF} {Length: 831} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=46.6, Expect=8e-07]} {RNA1509_27832, RNA1509_36958} {RNA1310_50245, RNA1509_27832, RNA1509_36958} {RNA1509_27832, RNA1509_36958, RNA815_48543}
73. MligTC455_42391 1050 21.88 Mlig455_010516, Mlig455_061820, Mlig455_061856, Mlig455_061864

Neo: -

Age: Down-Up-Up

3.188 - - 0.956 0.734 0.735 0.763

Mlig455_010516 {REF} {Length: 729} {RNA1509_38791} {RNA1310_69853, RNA1509_38791} {RNA1509_38791, RNA815_39199}

Mlig455_061820 {REF} {Length: 705} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}

Mlig455_061856 {REF} {Length: 708} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}

Mlig455_061864 {REF} {Length: 1146} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}
74. MligTC455_32922 646 13.45 Mlig455_037744, Mlig455_069919

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.335

Region-enriched R2: 1.859/0.01146

ANXA4 3.111 - 0.743 - 0.703 0.702 0.963

Mlig455_037744 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=312.1]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=1e-106]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=318, Expect=6e-100]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=328, Expect=2e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=317, Expect=2e-99]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=318, Expect=6e-100]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=298, Expect=7e-93]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722} {RNA1310_5582} {RNA815_3942.1}

Mlig455_069919 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=308.6]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=6e-107]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=316, Expect=3e-99]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=329, Expect=1e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=315, Expect=1e-98]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=316, Expect=3e-99]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=297, Expect=3e-92]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722, RNA1509_52903} {RNA1310_5582, RNA1509_19722, RNA1509_52903} {RNA1509_19722, RNA1509_52903, RNA815_3942.1}
75. MligTC455_53504 217 4.51 Mlig455_037385

Neo: -

Age: -

Region-enriched R2: 3.142/0.00738

CSMD1 2.931 - - - 0.989 0.958 0.984 Mlig455_037385 {REF} {Length: 2214} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=198.7]} {Human: ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=149, Expect=8e-37]} {Mouse: ENSMUSG00000028369, Svep1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=136, Expect=7e-33]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=134, Expect=5e-32]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=133, Expect=9e-32]} {Dmel: FBgn0032797, Hasp, Hig-anchoring scaffold protein, [RH, Score=218, Expect=3e-60]} {Celegans: WBGene00002976, lev-9, [RH, Score=244, Expect=4e-72]} {Smed: dd_Smed_v6_13071_0_1, dd_Smed_v6_13071_0_1, [RH, Score=296, Expect=1e-91]} {RNA1509_55985} {RNA1310_12867.1, RNA1509_55985} {RNA1509_55985, RNA815_9157}
76. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

2.894 0.956 - - - 0.958 0.980 Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
77. MligTC455_20574 3347 69.74 Mlig455_021418

Neo: -

Age: -

PCSK2 2.882 - - - 0.978 0.947 0.957 Mlig455_021418 {REF} {Length: 1212} {Pfam: Peptidase S8 pro-domain [PF16470.7, score=47.7]} {Human: ENSG00000125851, PCSK2, proprotein convertase subtilisin/kexin type 2, [Score=53.9, Expect=2e-08]} {Mouse: ENSMUSG00000027419, Pcsk2, proprotein convertase subtilisin/kexin type 2, [Score=52.8, Expect=4e-08]} {Dmel: FBgn0023179, amon, amontillado, [Score=55.8, Expect=2e-09]} {Celegans: WBGene00001172, egl-3, Neuroendocrine convertase 2, [Score=61.2, Expect=3e-11]} {Smed: dd_Smed_v6_1566_0_1, dd_Smed_v6_1566_0_1, [Score=65.1, Expect=1e-12]} {RNA1509_15978} {RNA1310_7333.1} {RNA815_2403.2}
78. MligTC455_53240 1601 33.35 Mlig455_025555

Neo: -

Age: -

Region-specific R2: 4.178

Region-enriched R2: 2.883/0.00000

2.862 - - - 0.952 0.946 0.964 Mlig455_025555 {REF} {Length: 2163} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=28.0]} {Dmel: FBgn0051221, CG31221, [RH, Score=69.7, Expect=2e-14]} {Celegans: WBGene00010290, F58H1.7, [Score=64.7, Expect=4e-13]} {Smed: dd_Smed_v6_2598_0_1, dd_Smed_v6_2598_0_1, [RH, Score=168, Expect=3e-53]} {RNA1509_58542} {RNA1310_40950, RNA1509_58542} {RNA1509_58542, RNA815_19778.1}
79. MligTC455_42513 70 1.45 Mlig455_023063, Mlig455_023065

Neo: -

Age: -

KCNC2 2.855 0.923 - - - 0.959 0.973

Mlig455_023063 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}

Mlig455_023065 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}
80. MligTC455_53414 331 6.9 Mlig455_053442

Neo: -

Age: -

Region-specific R2: 4.308

Region-enriched R2: 3.374/0.00040

RP1 2.851 - - - 0.976 0.903 0.972 Mlig455_053442 {REF} {Length: 1156} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.8]; Doublecortin [PF03607.19, score=103.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.0]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=473, Expect=5e-146]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=454, Expect=1e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.5, Expect=2e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=698, Expect=0.0]} {RNA1509_21828} {RNA1310_33070.1} {RNA815_13802.1}
81. MligTC455_53415 319 6.64 Mlig455_053444

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.862

Region-enriched R2: 4.179/0.00011

RP1 2.848 - - - 0.974 0.902 0.972 Mlig455_053444 {REF} {Length: 4944} {Pfam: PLAT/LH2 domain [PF01477.25, score=155.3]; Doublecortin [PF03607.19, score=100.5]; Embryo-specific protein 3, (ATS3) [PF06232.13, score=22.5]; Fibroblast growth factor [PF00167.20, score=18.6]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=471, Expect=6e-145]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=453, Expect=3e-136]} {Dmel: FBgn0261387, CG17528, [Score=56.6, Expect=1e-07]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.9, Expect=1e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=691, Expect=0.0]} {RNA1509_59703} {RNA1310_2710} {RNA815_17469}
82. MligTC455_24302 149 3.11 Mlig455_035632

Neo: -

Age: Up-Down-Up

KCNQ5 2.838 - - - 0.893 0.968 0.977 Mlig455_035632 {REF} {Length: 2263} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=124.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [Score=122, Expect=1e-28]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [Score=121, Expect=2e-28]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [Score=121, Expect=1e-28]; ENSMUSG00000028631, Kcnq4, potassium voltage-gated channel, subfamily Q, member 4, [Score=119, Expect=4e-28]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [Score=175, Expect=1e-46]} {Celegans: WBGene00002235, kqt-3, KQT-3 potassium channel; Potassium channel, KvQLT family, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_17359_0_2, dd_Smed_v6_17359_0_2, [Score=186, Expect=2e-52]} {RNA1509_34272} {RNA1310_3730.1} {RNA815_2787}
83. MligTC455_50927 254 5.29 Mlig455_070541, Mlig455_070562

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.296

Region-enriched R2: 7.883/0.00008
Region-enriched R3: 4.441/0.03979

FZD4 2.834 - - - 0.909 0.958 0.967

Mlig455_070541 {REF} {Length: 3522} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=471, Expect=6e-159]} {RNA1509_15834} {RNA1310_3800, RNA1509_15834} {RNA1509_15834, RNA815_19571}

Mlig455_070562 {REF} {Length: 3527} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=2e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=470, Expect=8e-159]} {RNA1509_15834} {RNA1310_3800} {RNA815_19571}
84. MligTC455_44120 125 2.61 Mlig455_041513

Neo: -

Age: Up-Down-Down

Region-enriched R2: 7.169/0.00020

2.829 - - - 0.970 0.878 0.981 Mlig455_041513 {REF} {Length: 644} {NoTransDecoderORF} {RNA1310_39164} {RNA815_4344}
85. MligTC455_41396 187 3.9 Mlig455_012937, Mlig455_031470

Neo: -

Age: -

Region-enriched R2: 4.167/0.01146

2.824 - - - 0.879 0.960 0.985

Mlig455_012937 {REF} {Length: 1911} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [Score=46.6, Expect=1e-06]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}

Mlig455_031470 {REF} {Length: 1745} {Dmel: FBgn0083971, CG34135, [RH, Score=60.1, Expect=1e-10]} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [RH, Score=96.3, Expect=3e-23]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}
86. MligTC455_46697 2841 59.19 Mlig455_009247

Neo: -

Age: -

Region-enriched R2: 2.282/0.00076
Region-enriched R7: 1.927/0.00163

Regeneration-downregulated BL: -2.847

Regeneration-depleted BL: -2.847

2.824 - - - 0.913 0.975 0.936 Mlig455_009247 {REF} {Length: 774} {Pfam: WD repeat binding protein EZH2 [PF11616.10, score=40.0]; NOPS (NUC059) domain [PF08075.13, score=34.4]} {RNA1509_12661} {RNA1310_96333} {RNA815_24028}
87. MligTC455_18619 527 10.97 Mlig455_030641, Mlig455_030999

Neo: -

Age: -

COL6A5 2.823 - - - 0.921 0.926 0.976

Mlig455_030641 {REF} {Length: 2413} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=111.9]} {Human: ENSG00000172752, COL6A5, collagen type VI alpha 5 chain, [Score=129, Expect=6e-31]} {Mouse: ENSMUSG00000032572, Col6a4, collagen, type VI, alpha 4, [Score=96.7, Expect=2e-20]; ENSMUSG00000028197, Col24a1, collagen, type XXIV, alpha 1, [Score=95.5, Expect=5e-20]} {Dmel: FBgn0000299, Col4a1, Collagen type IV alpha 1, [Score=91.3, Expect=7e-19]} {Celegans: WBGene00000708, col-135, COLlagen, [Score=99.0, Expect=1e-21]} {Smed: dd_Smed_v6_9565_0_1, dd_Smed_v6_9565_0_1, [Score=111, Expect=2e-25]} {RNA1509_35455} {RNA1310_11079.1} {RNA815_14901}

Mlig455_030999 {REF} {Length: 2379} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=97.0]} {Human: ENSG00000172752, COL6A5, collagen type VI alpha 5 chain, [Score=117, Expect=9e-27]} {Mouse: ENSMUSG00000031502, Col4a1, collagen, type IV, alpha 1, [Score=95.5, Expect=5e-20]; ENSMUSG00000026390, Marco, macrophage receptor with collagenous structure, [Score=91.7, Expect=3e-19]} {Dmel: FBgn0016075, vkg, viking, [Score=83.6, Expect=2e-16]} {Celegans: WBGene00000708, col-135, COLlagen, [Score=90.9, Expect=5e-19]} {Smed: dd_Smed_v6_9565_0_1, dd_Smed_v6_9565_0_1, [Score=105, Expect=1e-23]} {RNA1509_35455} {RNA1310_15043} {RNA815_14901}
88. MligTC455_27025 706 14.7 Mlig455_054786, Mlig455_054878

Neo: -

Age: -

Region-enriched R2: 3.519/0.00005

CD82 2.823 - - - 0.892 0.967 0.964

Mlig455_054786 {REF} {Length: 2796} {Pfam: Tetraspanin family [PF00335.22, score=142.8]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=86.3, Expect=4e-19]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=94.0, Expect=3e-22]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=98.6, Expect=6e-24]} {Celegans: WBGene00006632, tsp-6, Tetraspanin, [Score=74.7, Expect=1e-15]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1310_8032.1, RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1509_20389, RNA1509_43644, RNA1509_56428, RNA815_3380.1}

Mlig455_054878 {REF} {Length: 4398} {Pfam: Tetraspanin family [PF00335.22, score=143.7]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=84.7, Expect=2e-18]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=92.4, Expect=2e-21]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=99.8, Expect=4e-24]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [RH, Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_56428} {RNA1310_8032.2} {RNA815_3380.1}
89. MligTC455_33832 112 2.34 Mlig455_029411

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.300/0.00016
Region-enriched R8: 4.136/0.03070

GLRA3 2.822 - - - 0.953 0.959 0.910 Mlig455_029411 {REF} {Length: 3686} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=149.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.5]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=257, Expect=5e-80]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=253, Expect=3e-78]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=250, Expect=4e-77]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=251, Expect=2e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=249, Expect=5e-77]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=2e-76]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=243, Expect=1e-74]} {Dmel: FBgn0024963, GluClalpha, [Score=253, Expect=2e-78]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=259, Expect=7e-81]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=480, Expect=1e-167]} {RNA1509_35986} {RNA1310_35528} {RNA815_35433}
90. MligTC455_28559 6127 127.65 Mlig455_028180

Neo: -

Age: -

Region-specific R2: 2.829

Region-enriched R2: 1.854/0.00000

Regeneration-depleted BL: -1.839
Regeneration-depleted TP: -1.683

SYT11 2.813 - - - 0.957 0.936 0.920 Mlig455_028180 {REF} {Length: 2785} {Pfam: C2 domain [PF00168.32, score=161.4]} {Human: ENSG00000132718, SYT11, synaptotagmin 11, [RH, Score=305, Expect=7e-100]} {Mouse: ENSMUSG00000068923, Syt11, synaptotagmin XI, [RH, Score=306, Expect=2e-100]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [RH, Score=351, Expect=1e-117]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [RH, Score=232, Expect=2e-72]} {Smed: dd_Smed_v6_7243_0_1, dd_Smed_v6_7243_0_1, [RH, Score=399, Expect=2e-137]} {RNA1509_303} {RNA1310_7615, RNA1509_303} {RNA1509_303, RNA815_4825}
91. MligTC455_51763 1421 29.6 Mlig455_015843

Neo: -

Age: -

Region-specific R2: 3.066

Region-enriched R2: 2.560/0.00003

2.812 - - - 0.935 0.992 0.885 Mlig455_015843 {REF} {Length: 805} {RNA1509_26419, RNA1509_39553, RNA1509_39658} {RNA1310_60107.2, RNA1509_26419, RNA1509_39553, RNA1509_39658} {RNA1509_26419, RNA1509_39553, RNA1509_39658, RNA815_31573}
92. MligTC455_05889 28 0.58 Mlig455_027604, Mlig455_047689, Mlig455_047690

Neo: -

Age: -

TLR4 2.812 - - - 0.950 0.898 0.964

Mlig455_027604 {REF} {Length: 3445} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_22808}

Mlig455_047689 {REF} {Length: 352} {Pfam: Leucine rich repeat [PF13855.8, score=35.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {RNA1310_7084} {RNA815_47088}

Mlig455_047690 {REF} {Length: 346} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_47699}
93. MligTC455_24270 71 1.47 Mlig455_005120

Neo: -

Age: -

CHRNA7 2.81 - - - 0.937 0.910 0.963 Mlig455_005120 {REF} {Length: 1530} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=115.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.6]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=148, Expect=4e-39]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=147, Expect=5e-39]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=146, Expect=2e-38]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=1e-36]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=135, Expect=5e-34]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=134, Expect=9e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=133, Expect=4e-34]} {RNA1509_43533} {RNA1310_20839.2} {RNA815_22406}
94. MligTC455_54282 74 1.54 Mlig455_020191

Neo: -

Age: -

2.808 - - - 0.904 0.931 0.973 Mlig455_020191 {REF} {Length: 937} {RNA1509_48973} {RNA1310_40738.2} {RNA815_31898}
95. MligTC455_23544 169 3.53 Mlig455_021925

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.394/0.00033

DDR2 2.805 - - - 0.940 0.954 0.911 Mlig455_021925 {REF} {Length: 4813} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=205.5]; Protein kinase domain [PF00069.27, score=103.7]; F5/8 type C domain [PF00754.27, score=57.5]} {Human: ENSG00000162733, DDR2, discoidin domain receptor tyrosine kinase 2, [Score=249, Expect=1e-68]} {Mouse: ENSMUSG00000026674, Ddr2, discoidin domain receptor family, member 2, [Score=251, Expect=1e-69]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=238, Expect=3e-64]} {Celegans: WBGene00017381, svh-4, Discoidin domain-containing receptor tyrosine kinase B, [Score=176, Expect=3e-45]} {Smed: dd_Smed_v6_22332_0_1, dd_Smed_v6_22332_0_1, [Score=187, Expect=2e-48]} {RNA1509_46581} {RNA1310_21361} {RNA815_21661}
96. MligTC455_13099 93 1.93 Mlig455_057504

Neo: -

Age: -

2.803 - - 0.890 - 0.921 0.992 Mlig455_057504 {REF} {Length: 2002} {RNA1310_15168} {RNA815_31864}
97. MligTC455_28560 6060 126.24 Mlig455_028251

Neo: -

Age: -

Region-specific R2: 2.839

Region-enriched R2: 1.867/0.00000

Regeneration-depleted BL: -1.887
Regeneration-depleted TP: -1.666

SYT11 2.801 - - - 0.957 0.924 0.920 Mlig455_028251 {REF} {Length: 2851} {Pfam: C2 domain [PF00168.32, score=161.3]} {Human: ENSG00000132718, SYT11, synaptotagmin 11, [RH, Score=304, Expect=1e-99]} {Mouse: ENSMUSG00000068923, Syt11, synaptotagmin XI, [RH, Score=305, Expect=3e-100]} {Dmel: FBgn0028400, Syt4, Synaptotagmin 4, [RH, Score=353, Expect=3e-118]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [RH, Score=233, Expect=4e-73]} {Smed: dd_Smed_v6_7243_0_1, dd_Smed_v6_7243_0_1, [RH, Score=397, Expect=6e-137]} {RNA1509_17703, RNA1509_303, RNA1509_58747} {RNA1310_7615, RNA1509_17703, RNA1509_58747} {RNA1509_17703, RNA1509_58747, RNA815_4825}
98. MligTC455_47261 1918 39.96 Mlig455_033946

Neo: -

Age: -

Region-specific R2: 4.808

Region-enriched R2: 4.545/0.00000

2.79 - - - 0.941 0.890 0.959 Mlig455_033946 {REF} {Length: 2098} {RNA1509_18239, RNA1509_26992, RNA1509_32368} {RNA1310_36725.1, RNA1509_18239, RNA1509_26992, RNA1509_32368} {RNA1509_18239, RNA1509_26992, RNA1509_32368, RNA815_10268.1}
99. MligTC455_50532 259 5.4 Mlig455_019987

Neo: -

Age: Down-Up-Down

NEFH 2.789 - - - 0.900 0.935 0.954 Mlig455_019987 {REF} {Length: 4055} {Human: ENSG00000100285, NEFH, neurofilament heavy, [Score=65.5, Expect=3e-10]} {RNA1509_41200, RNA1509_57173} {RNA1310_3614.2, RNA1509_41200, RNA1509_57173} {RNA1509_41200, RNA1509_57173, RNA815_5328}
100. MligTC455_48218 1632 34 Mlig455_054782, Mlig455_054874

Neo: -

Age: Down-Down-Up

Region-specific R2: 3.792

Region-enriched R2: 2.673/0.00000

Regeneration-downregulated BL: -2.255

Regeneration-depleted BL: -2.255

2.787 - - - 0.959 0.893 0.935

Mlig455_054782 {REF} {Length: 1928} {RNA1509_16585} {RNA1310_35143} {RNA815_1375.1}

Mlig455_054874 {REF} {Length: 2445} {RNA1509_16585} {RNA1310_35143, RNA1509_16585} {RNA1509_16585, RNA815_1375.1}

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