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Results for MligTC455_13101

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_13101 40 0.83 Mlig455_041354

Neo: -

Age: Up-Down-Down

NWD2 Mlig455_041354 {REF} {Length: 5076} {Pfam: AAA ATPase domain [PF13191.8, score=35.4]; NACHT domain [PF05729.14, score=28.8]; WD domain, G-beta repeat [PF00400.34, score=23.9]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=353, Expect=5e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=338, Expect=3e-94]} {Dmel: FBgn0038397, CG10185, [RH, Score=1016, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [Score=738, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=212, Expect=4e-55]} {RNA1509_20730} {RNA1310_1147} {RNA815_11922}

Cumulative graph for MligTC455_13101

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 5.724 1.156 0.07558 0.60692
RegionR2 3.114 1.156 0.89032 1.00000
RegionR3 -2.336 1.156 0.99989 1.00000
RegionR4 1.144 1.156 0.18363 0.45532
RegionR5 -2.502 1.156 0.99978 1.00000
RegionR6 -2.593 1.156 0.99985 1.00000
RegionR7 -1.586 1.156 0.99979 1.00000
RegionR8 -0.966 1.156 1.00000 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.141 1.156 0.16991 0.91300
RegenerationR2 0.756 1.156 0.71037 0.96013
RegenerationR3 0.27 1.156 0.93557 1.00000
RegenerationR4 -0.297 1.156 0.35762 0.78642
RegenerationR5 -0.515 1.156 0.99987 1.00000
RegenerationR6 1.649 1.156 0.79782 0.97572
RegenerationBL -1.037 1.156 0.99981 1.00000
RegenerationTP -0.909 1.156 0.99983 1.00000


Genes with expression patterns similar to MligTC455_13101

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_13101 40 0.83 Mlig455_041354

Neo: -

Age: Up-Down-Down

NWD2 3 - - 1.000 - 1.000 1.000 Mlig455_041354 {REF} {Length: 5076} {Pfam: AAA ATPase domain [PF13191.8, score=35.4]; NACHT domain [PF05729.14, score=28.8]; WD domain, G-beta repeat [PF00400.34, score=23.9]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=353, Expect=5e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=338, Expect=3e-94]} {Dmel: FBgn0038397, CG10185, [RH, Score=1016, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [Score=738, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=212, Expect=4e-55]} {RNA1509_20730} {RNA1310_1147} {RNA815_11922}
2. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 2.969 - - 0.978 - 0.997 0.994

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
3. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

2.952 - - 0.986 - 0.976 0.990

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
4. MligTC455_45039 168 3.49 Mlig455_040482, Mlig455_040487

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.332/0.02336

2.945 - - 0.990 - 0.961 0.994

Mlig455_040482 {REF} {Length: 1774} {RNA1310_20941} {RNA815_45079}

Mlig455_040487 {REF} {Length: 5763} {tRNA: Val(CAC),pseudo, score=20.2} {Celegans: WBGene00022195, Y71H2B.5, [Score=146, Expect=8e-36]} {Smed: dd_Smed_v6_16438_0_2, dd_Smed_v6_16438_0_2, [Score=188, Expect=1e-49]} {RNA1509_21228} {RNA1310_20941} {RNA815_45079}
5. MligTC455_09456 47 0.97 Mlig455_029993

Neo: -

Age: -

Region-enriched R2: 5.041/0.00960

2.941 - - 0.960 - 0.992 0.989 Mlig455_029993 {REF} {Length: 3167} {RNA1509_44134} {RNA1310_31411} {RNA815_45870}
6. MligTC455_14716 29 0.61 Mlig455_043633

Neo: -

Age: -

ANGPTL2 2.941 - - 0.986 - 0.973 0.982 Mlig455_043633 {REF} {Length: 1106} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=157.6]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=134, Expect=2e-35]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=133, Expect=4e-35]; ENSG00000085265, FCN1, ficolin 1, [Score=132, Expect=8e-36]; ENSG00000160339, FCN2, ficolin 2, [Score=128, Expect=4e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=119, Expect=6e-32]} {Celegans: WBGene00017013, ensh-1, [Score=57.8, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=114, Expect=1e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
7. MligTC455_41540 190 3.96 Mlig455_060056

Neo: -

Age: -

Region-enriched R2: 6.605/0.00196

GLUL 2.935 - - 0.969 - 0.969 0.997 Mlig455_060056 {REF} {Length: 1355} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.3]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=47.5]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=511, Expect=1e-180]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=511, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=515, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=545, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.2} {RNA815_4116.6}
8. MligTC455_42510 125 2.6 Mlig455_025998, Mlig455_070424

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.702

2.932 - - 0.988 - 0.951 0.993

Mlig455_025998 {REF} {Length: 1369} {RNA1310_73875.1}

Mlig455_070424 {REF} {Length: 1082} {RNA1310_73875.1}
9. MligTC455_26255 126 2.63 Mlig455_053706

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.424/0.00107
Region-enriched R4: 3.360/0.04239

FZD5 2.927 - - 0.983 - 0.947 0.997 Mlig455_053706 {REF} {Length: 3671} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=393.1]; Fz domain [PF01392.24, score=105.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=412, Expect=5e-137]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_49831} {RNA1310_28187, RNA1509_49831} {RNA1509_49831, RNA815_16996}
10. MligTC455_06015 22 0.45 Mlig455_025599

Neo: -

Age: -

2.926 - - 0.940 - 0.989 0.997 Mlig455_025599 {REF} {Length: 4401} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.9]; WSC domain [PF01822.21, score=18.9]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=50.8, Expect=3e-06]} {Smed: dd_Smed_v6_17245_0_1, dd_Smed_v6_17245_0_1, [Score=59.7, Expect=4e-09]}
11. MligTC455_15450 19 0.39 Mlig455_006618

Neo: -

Age: -

2.926 - - 0.960 - 0.969 0.997 Mlig455_006618 {REF} {Length: 653} {Pfam: WSC domain [PF01822.21, score=30.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.5, Expect=7e-09]} {RNA1310_35396.1} {RNA815_56551}
12. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 2.925 - - 0.962 - 0.981 0.982 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
13. MligTC455_50253 44 0.92 Mlig455_031495

Neo: -

Age: -

GABRB2 2.924 - - 0.969 - 0.959 0.996 Mlig455_031495 {REF} {Length: 2129} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=58.3]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [Score=71.2, Expect=6e-14]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [Score=67.8, Expect=1e-12]; ENSMUSG00000029212, Gabrb1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, [Score=67.4, Expect=1e-12]} {Dmel: FBgn0024963, GluClalpha, [Score=54.3, Expect=3e-08]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=70.1, Expect=9e-14]} {RNA1310_46931} {RNA815_25428}
14. MligTC455_35583 48 0.99 Mlig455_009953

Neo: -

Age: -

2.923 - - 0.967 - 0.965 0.991 Mlig455_009953 {REF} {Length: 919} {Pfam: Lectin C-type domain [PF00059.23, score=25.9]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=61.6, Expect=2e-11]} {RNA1509_20946} {RNA1310_71370} {RNA815_4785.4}
15. MligTC455_18682 1190 24.79 Mlig455_037756

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.877

Region-enriched R2: 4.609/0.00000

2.921 - - 0.960 - 0.965 0.996 Mlig455_037756 {REF} {Length: 1188} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
16. MligTC455_49491 136 2.83 Mlig455_054796

Neo: -

Age: -

Region-enriched R2: 7.065/0.00003

2.921 - - 0.961 - 0.964 0.996 Mlig455_054796 {REF} {Length: 1567} {RNA1509_22234} {RNA1310_23973} {RNA815_10832}
17. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 2.918 - - 0.966 - 0.981 0.971 Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
18. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 2.914 - - 0.964 - 0.953 0.997 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
19. MligTC455_39096 110 2.29 Mlig455_019781, Mlig455_019803

Neo: -

Age: -

2.914 - - 0.978 - 0.939 0.997

Mlig455_019781 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1310_34740} {RNA815_15663}

Mlig455_019803 {REF} {Length: 1107} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.1]} {RNA1310_34740} {RNA815_15663}
20. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

2.907 - - 0.975 - 0.938 0.994 Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
21. MligTC455_16233 307 6.4 Mlig455_011368

Neo: -

Age: logFC(26M/2M)=-1.958

2.903 - - 0.964 - 0.945 0.994 Mlig455_011368 {REF} {Length: 1236} {RNA1509_44264} {RNA1310_62516} {RNA815_23574}
22. MligTC455_14715 31 0.65 Mlig455_043609

Neo: -

Age: -

ANGPTL1 2.902 - - 0.975 - 0.945 0.982 Mlig455_043609 {REF} {Length: 1252} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=154.2]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=131, Expect=2e-34]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=128, Expect=2e-33]; ENSG00000085265, FCN1, ficolin 1, [Score=128, Expect=2e-34]; ENSG00000160339, FCN2, ficolin 2, [Score=125, Expect=5e-34]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=129, Expect=7e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=128, Expect=2e-33]} {Dmel: FBgn0033312, CG8642, [RH, Score=122, Expect=1e-31]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=112, Expect=7e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
23. MligTC455_18579 143 2.97 Mlig455_047208, Mlig455_048469

Neo: -

Age: -

GRIK2, GRIK3 2.9 - - 0.940 - 0.968 0.992

Mlig455_047208 {REF} {Length: 5413} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=92.5]; Ligand-gated ion channel [PF00060.28, score=84.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=49.2]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=194, Expect=2e-50]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=193, Expect=5e-50]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=192, Expect=2e-49]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=192, Expect=2e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=191, Expect=3e-49]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=194, Expect=1e-50]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=194, Expect=3e-50]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=191, Expect=2e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=191, Expect=2e-49]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=188, Expect=2e-48]} {Dmel: FBgn0038837, CG3822, [Score=185, Expect=9e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=200, Expect=7e-53]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=341, Expect=5e-106]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}

Mlig455_048469 {REF} {Length: 3740} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=95.9]; Ligand-gated ion channel [PF00060.28, score=82.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=51.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=190, Expect=6e-50]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=187, Expect=5e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=185, Expect=3e-48]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=184, Expect=1e-47]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=189, Expect=7e-50]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=187, Expect=6e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=185, Expect=2e-48]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=183, Expect=9e-48]} {Dmel: FBgn0038837, CG3822, [Score=183, Expect=4e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=183, Expect=3e-48]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=338, Expect=6e-108]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}
24. MligTC455_44380 28 0.58 Mlig455_000679, Mlig455_000682, Mlig455_000734

Neo: -

Age: -

2.9 - - 0.941 - 0.960 0.999

Mlig455_000679 {REF} {Length: 966} {Pfam: PAN domain [PF00024.28, score=22.4]} {RNA1310_44307} {RNA815_33128}

Mlig455_000682 {REF} {Length: 1005} {Pfam: WSC domain [PF01822.21, score=41.4]; PAN domain [PF00024.28, score=21.7]} {RNA1310_44307} {RNA815_33128}

Mlig455_000734 {REF} {Length: 1006} {Pfam: WSC domain [PF01822.21, score=41.4]; PAN domain [PF00024.28, score=21.7]} {RNA1310_44307} {RNA815_33128}
25. MligTC455_32028 19 0.39 Mlig455_019343, Mlig455_019346

Neo: -

Age: -

GRIA2 2.899 - - 0.973 - 0.940 0.986

Mlig455_019343 {REF} {Length: 3241} {Pfam: Ligand-gated ion channel [PF00060.28, score=96.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=57.9]; Receptor family ligand binding region [PF01094.30, score=49.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.0]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=150, Expect=1e-36]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=149, Expect=2e-36]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=146, Expect=2e-35]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=144, Expect=9e-35]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=144, Expect=1e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=150, Expect=5e-37]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=150, Expect=8e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=145, Expect=3e-35]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=3e-35]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=144, Expect=5e-35]} {Dmel: FBgn0039927, CG11155, [Score=158, Expect=1e-39]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=125, Expect=3e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=250, Expect=2e-75]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.1}

Mlig455_019346 {REF} {Length: 519} {Pfam: Receptor family ligand binding region [PF01094.30, score=21.5]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.2}
26. MligTC455_44176 89 1.85 Mlig455_022911

Neo: -

Age: -

TNKS 2.892 - - 0.960 - 0.968 0.964 Mlig455_022911 {REF} {Length: 1883} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=67.0]; Ankyrin repeats (3 copies) [PF12796.9, score=64.6]; Ankyrin repeats (many copies) [PF13857.8, score=59.2]; Ankyrin repeat [PF13606.8, score=50.9]; Ankyrin repeat [PF00023.32, score=50.1]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=57.8, Expect=3e-08]; ENSG00000285372, AC270292.3, tankyrase, [Score=56.6, Expect=7e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=55.5, Expect=2e-07]} {Mouse: ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=57.8, Expect=1e-08]; ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=57.8, Expect=1e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=57.8, Expect=2e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=57.4, Expect=1e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.8, Expect=9e-08]; ENSMUSG00000063932, Poteg, POTE ankyrin domain family, member G, [Score=55.5, Expect=8e-08]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.5, Expect=1e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=55.5, Expect=4e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=55.1, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=55.1, Expect=8e-08]} {Dmel: FBgn0040752, Prosap, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_2072_0_22, dd_Smed_v6_2072_0_22, [Score=62.0, Expect=4e-10]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
27. MligTC455_18683 419 8.74 Mlig455_069928

Neo: -

Age: -

Region-specific R2: 6.066

Region-enriched R2: 4.921/0.00217

2.89 - - 0.958 - 0.936 0.996 Mlig455_069928 {REF} {Length: 845} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
28. MligTC455_24753 11 0.23 Mlig455_016700

Neo: -

Age: -

2.89 - - 0.970 - 0.963 0.957 Mlig455_016700 {REF} {Length: 1032} {Pfam: PAN domain [PF00024.28, score=20.1]} {RNA1310_36328.1} {RNA815_39270}
29. MligTC455_39890 162 3.37 Mlig455_047281, Mlig455_047331, Mlig455_069333

Neo: -

Age: -

Region-enriched R2: 6.097/0.00148

PLSCR1 2.889 - - 0.957 - 0.939 0.993

Mlig455_047281 {REF} {Length: 1404} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_047331 {REF} {Length: 1395} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_069333 {REF} {Length: 1416} {Pfam: Scramblase [PF03803.17, score=248.7]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=226, Expect=1e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=228, Expect=2e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=223, Expect=1e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=224, Expect=2e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=4e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=304, Expect=2e-103]} {RNA1310_29769} {RNA815_41335}
30. MligTC455_48634 30 0.62 Mlig455_006052, Mlig455_068060

Neo: -

Age: -

ANGPTL4, FCN2 2.884 - - 0.980 - 0.908 0.996

Mlig455_006052 {REF} {Length: 2091} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=64.0]} {Human: ENSG00000160339, FCN2, ficolin 2, [Score=83.6, Expect=2e-17]} {Mouse: ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=71.6, Expect=9e-14]} {Dmel: FBgn0034160, CG5550, [Score=67.4, Expect=2e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=62.0, Expect=2e-10]} {RNA1310_118683}

Mlig455_068060 {REF} {Length: 1573} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.6]} {Human: ENSG00000167772, ANGPTL4, angiopoietin like 4, [Score=53.9, Expect=9e-08]} {Mouse: ENSMUSG00000028553, Angptl3, angiopoietin-like 3, [Score=50.4, Expect=9e-07]} {Dmel: FBgn0050280, CG30280, [Score=57.0, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=53.9, Expect=3e-08]} {RNA1310_87835}
31. MligTC455_33040 203 4.23 Mlig455_032497

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R2: 4.005/0.00408

PKD2L1 2.883 - - 0.951 - 0.954 0.978 Mlig455_032497 {REF} {Length: 3318} {Pfam: Polycystin cation channel [PF08016.14, score=293.1]; Ion transport protein [PF00520.33, score=39.7]} {Human: ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [Score=236, Expect=4e-66]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=261, Expect=3e-73]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=131, Expect=5e-31]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=180, Expect=1e-47]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=641, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
32. MligTC455_43072 81 1.68 Mlig455_042521

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.590/0.02161

2.882 - - 0.980 - 0.914 0.988 Mlig455_042521 {REF} {Length: 1049} {RNA1509_46101} {RNA1310_32444} {RNA815_30668}
33. MligTC455_18774 91 1.89 Mlig455_032103

Neo: -

Age: -

2.88 - - 0.966 - 0.920 0.994 Mlig455_032103 {REF} {Length: 728} {RNA1310_56123.2} {RNA815_28679}
34. MligTC455_17568 33 0.68 Mlig455_059349, Mlig455_065584

Neo: -

Age: -

2.877 - - 0.931 - 0.949 0.997

Mlig455_059349 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}

Mlig455_065584 {REF} {Length: 1132} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}
35. MligTC455_15679 88 1.82 Mlig455_057219

Neo: -

Age: Down-Up-Up

WSCD2 2.875 - - 0.961 - 0.917 0.997 Mlig455_057219 {REF} {Length: 1035} {Pfam: WSC domain [PF01822.21, score=55.1]; PAN domain [PF00024.28, score=27.0]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.8, Expect=2e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=51.6, Expect=3e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.5, Expect=5e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
36. MligTC455_44177 70 1.46 Mlig455_022828, Mlig455_022920

Neo: -

Age: -

TNKS 2.871 - - 0.951 - 0.976 0.944

Mlig455_022828 {REF} {Length: 1654} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=58.3]; Ankyrin repeats (many copies) [PF13637.8, score=51.4]; Ankyrin repeats (many copies) [PF13857.8, score=43.5]; Ankyrin repeat [PF00023.32, score=38.9]; Ankyrin repeat [PF13606.8, score=35.6]} {Dmel: FBgn0039955, CG41099, [Score=56.6, Expect=5e-08]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.1, Expect=4e-07]} {Smed: dd_Smed_v6_11252_0_1, dd_Smed_v6_11252_0_1, [Score=50.8, Expect=1e-06]} {RNA1509_39040} {RNA1310_886.1} {RNA815_14632}

Mlig455_022920 {REF} {Length: 1424} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=65.4]; Ankyrin repeats (3 copies) [PF12796.9, score=61.1]; Ankyrin repeats (many copies) [PF13857.8, score=57.9]; Ankyrin repeat [PF13606.8, score=50.1]; Ankyrin repeat [PF00023.32, score=49.7]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=56.2, Expect=9e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000285372, AC270292.3, tankyrase, [Score=55.5, Expect=2e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=54.3, Expect=3e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=53.5, Expect=8e-07]} {Mouse: ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=56.6, Expect=3e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=56.6, Expect=3e-08]; ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=56.2, Expect=3e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=56.2, Expect=6e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.1, Expect=2e-07]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.1, Expect=2e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=54.3, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=53.9, Expect=2e-07]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0040752, Prosap, [Score=58.5, Expect=1e-08]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=51.6, Expect=9e-07]} {Smed: dd_Smed_v6_2072_0_20, dd_Smed_v6_2072_0_20, [Score=59.3, Expect=3e-09]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
37. MligTC455_49958 16 0.32 Mlig455_014437, Mlig455_070189

Neo: -

Age: -

2.871 - - 0.976 - 0.898 0.997

Mlig455_014437 {REF} {Length: 921} {RNA1310_45206} {RNA815_28788}

Mlig455_070189 {REF} {Length: 739} {RNA1310_45206} {RNA815_28788}
38. MligTC455_19708 304 6.32 Mlig455_009784

Neo: -

Age: -

Region-enriched R2: 6.355/0.00039

2.87 - - 0.923 - 0.955 0.992 Mlig455_009784 {REF} {Length: 826} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.3]} {RNA1509_54211} {RNA1310_54505.1, RNA1509_54211} {RNA1509_54211, RNA815_29389}
39. MligTC455_28693 60 1.26 Mlig455_022354

Neo: -

Age: -

2.867 - - 0.980 - 0.891 0.996 Mlig455_022354 {REF} {Length: 816} {Pfam: WSC domain [PF01822.21, score=53.0]; PAN domain [PF00024.28, score=20.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=48.1, Expect=2e-06]} {RNA1509_43359} {RNA1310_59466.1} {RNA815_19988}
40. MligTC455_18891 275 5.73 Mlig455_024941

Neo: -

Age: -

Region-enriched R2: 2.016/0.02450

2.866 - - 0.965 - 0.926 0.975 Mlig455_024941 {REF} {Length: 394} {NoTransDecoderORF} {RNA1509_45136} {RNA1310_56753} {RNA815_28269}
41. MligTC455_24924 19 0.39 Mlig455_022395

Neo: -

Age: -

2.866 - - 0.985 - 0.905 0.976 Mlig455_022395 {REF} {Length: 2109} {RNA1310_106878}
42. MligTC455_52128 26 0.54 Mlig455_056382

Neo: -

Age: -

2.865 - - 0.938 - 0.977 0.950 Mlig455_056382 {REF} {Length: 892} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=20.5]; Ankyrin repeat [PF00023.32, score=19.7]} {RNA1310_149618}
43. MligTC455_20722 36 0.74 Mlig455_001696, Mlig455_066078, Mlig455_066120

Neo: -

Age: -

2.864 - - 0.938 - 0.950 0.976

Mlig455_001696 {REF} {Length: 1535} {RNA1310_134737} {RNA815_57224}

Mlig455_066078 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=20.4]} {RNA1310_134737} {RNA815_57224}

Mlig455_066120 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=25.9]} {RNA1310_134737} {RNA815_57224}
44. MligTC455_41595 483 10.07 Mlig455_065096

Neo: -

Age: -

2.864 - - 0.944 - 0.981 0.939 Mlig455_065096 {REF} {Length: 1103} {RNA1310_35732} {RNA815_16408}
45. MligTC455_44687 22 0.45 Mlig455_061067

Neo: -

Age: -

2.864 - - 0.988 - 0.894 0.982 Mlig455_061067 {REF} {Length: 2106} {Pfam: PAN domain [PF00024.28, score=19.4]} {RNA1509_27043} {RNA1310_39798} {RNA815_59357}
46. MligTC455_50566 40 0.84 Mlig455_061499

Neo: -

Age: -

Region-enriched R2: 5.243/0.02447

2.863 - - 0.977 - 0.978 0.908 Mlig455_061499 {REF} {Length: 484} {NoTransDecoderORF} {RNA1310_94077} {RNA815_47403}
47. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 2.862 - - 0.920 - 0.955 0.987 Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
48. MligTC455_11229 51 1.06 Mlig455_054212

Neo: -

Age: -

2.859 - - 0.956 - 0.907 0.996 Mlig455_054212 {REF} {Length: 1481} {RNA1310_23944} {RNA815_32018}
49. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

2.859 - - 0.961 - 0.901 0.997 Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
50. MligTC455_40353 39 0.82 Mlig455_024525

Neo: -

Age: -

2.858 - - 0.968 - 0.911 0.979 Mlig455_024525 {REF} {Length: 1158} {RNA1310_29008}
51. MligTC455_10899 46 0.95 Mlig455_013784, Mlig455_013915

Neo: -

Age: -

2.857 - - 0.983 - 0.886 0.988

Mlig455_013784 {REF} {Length: 1362} {Pfam: Glycine rich protein [PF12810.9, score=20.8]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}

Mlig455_013915 {REF} {Length: 1516} {Pfam: Glycine rich protein [PF12810.9, score=20.3]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}
52. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

2.855 - - 0.939 - 0.927 0.989 Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
53. MligTC455_45032 56 1.16 Mlig455_034186

Neo: -

Age: -

KREMEN1 2.854 - - 0.984 - 0.873 0.997 Mlig455_034186 {REF} {Length: 1010} {Pfam: WSC domain [PF01822.21, score=53.3]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=51.2, Expect=3e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=53.9, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=47.8, Expect=3e-06]} {RNA1310_39474.1} {RNA815_33128}
54. MligTC455_50546 21 0.44 Mlig455_045408

Neo: -

Age: -

2.853 - - 0.985 - 0.881 0.987 Mlig455_045408 {REF} {Length: 1345} {RNA1310_102440}
55. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

GRIA2 2.853 - - 0.976 - 0.909 0.968

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
56. MligTC455_42376 61 1.27 Mlig455_069890

Neo: -

Age: -

2.851 - - 0.937 - 0.989 0.925 Mlig455_069890 {REF} {Length: 630} {TRANSSPLICED} {Pfam: PAN domain [PF00024.28, score=26.1]} {RNA1509_53783} {RNA1310_37190} {RNA815_24434}
57. MligTC455_42963 247 5.15 Mlig455_002825

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.597

Region-enriched R2: 5.687/0.00012

2.851 - - 0.976 - 0.876 0.999 Mlig455_002825 {REF} {Length: 726} {RNA1310_78982} {RNA815_41084}
58. MligTC455_50643 38 0.8 Mlig455_007952, Mlig455_008053

Neo: -

Age: -

VSX1 2.851 - - 0.900 - 0.981 0.970

Mlig455_007952 {REF} {Length: 1358} {Pfam: Homeodomain [PF00046.31, score=79.6]} {Human: ENSG00000100987, VSX1, visual system homeobox 1, [RH, Score=197, Expect=4e-60]; ENSG00000119614, VSX2, visual system homeobox 2, [RH, Score=196, Expect=2e-59]} {Mouse: ENSMUSG00000021239, Vsx2, visual system homeobox 2, [RH, Score=196, Expect=6e-60]; ENSMUSG00000033080, Vsx1, visual system homeobox 1, [RH, Score=195, Expect=2e-59]} {Dmel: FBgn0263512, Vsx2, Visual system homeobox 2, [RH, Score=204, Expect=3e-60]} {Celegans: WBGene00000435, ceh-10, Homeobox protein ceh-10, [RH, Score=204, Expect=2e-63]} {Smed: dd_Smed_v6_19286_0_1, dd_Smed_v6_19286_0_1, [RH, Score=211, Expect=2e-66]} {RNA1310_76393} {RNA815_51313}

Mlig455_008053 {REF} {Length: 2271} {RNA1310_76393} {RNA815_51313}
59. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

2.85 - - 0.899 - 0.978 0.973 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
60. MligTC455_42513 70 1.45 Mlig455_023063, Mlig455_023065

Neo: -

Age: -

KCNC2 2.85 - - 0.917 - 0.948 0.985

Mlig455_023063 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}

Mlig455_023065 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}
61. MligTC455_24302 149 3.11 Mlig455_035632

Neo: -

Age: Up-Down-Up

KCNQ5 2.849 - - 0.899 - 0.959 0.991 Mlig455_035632 {REF} {Length: 2263} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=124.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [Score=122, Expect=1e-28]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [Score=121, Expect=2e-28]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [Score=121, Expect=1e-28]; ENSMUSG00000028631, Kcnq4, potassium voltage-gated channel, subfamily Q, member 4, [Score=119, Expect=4e-28]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [Score=175, Expect=1e-46]} {Celegans: WBGene00002235, kqt-3, KQT-3 potassium channel; Potassium channel, KvQLT family, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_17359_0_2, dd_Smed_v6_17359_0_2, [Score=186, Expect=2e-52]} {RNA1509_34272} {RNA1310_3730.1} {RNA815_2787}
62. MligTC455_42994 1521 31.7 Mlig455_035840

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

Region-enriched R2: 1.854/0.00052

2.847 - - 0.923 - 0.947 0.977 Mlig455_035840 {REF} {Length: 1436} {RNA1509_29485, RNA1509_42231} {RNA1310_26640, RNA1509_29485, RNA1509_42231} {RNA1509_29485, RNA1509_42231, RNA815_37260}
63. MligTC455_13171 25 0.53 Mlig455_005963, Mlig455_005967

Neo: -

Age: -

2.846 - - 0.944 - 0.908 0.994

Mlig455_005963 {REF} {Length: 2617} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}

Mlig455_005967 {REF} {Length: 1405} {Pfam: Lectin C-type domain [PF00059.23, score=20.7]} {RNA1509_20946} {RNA1310_146331} {RNA815_35450}
64. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

2.845 - - 0.909 - 0.956 0.980 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
65. MligTC455_29012 227 4.74 Mlig455_004572

Neo: -

Age: Down-Down-Up

TMEM30A 2.844 - - 0.950 - 0.925 0.969 Mlig455_004572 {REF} {Length: 3160} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=265.5]} {Human: ENSG00000112697, TMEM30A, transmembrane protein 30A, [RH, Score=234, Expect=7e-73]} {Mouse: ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [RH, Score=241, Expect=7e-76]} {Dmel: FBgn0030752, CG9947, [RH, Score=294, Expect=9e-97]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [Score=246, Expect=3e-78]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=275, Expect=2e-89]} {RNA1509_38539} {RNA1310_9371} {RNA815_12157}
66. MligTC455_19042 3679 76.64 Mlig455_030661

Neo: -

Age: logFC(26M/2M)=0.480

Region-specific R2: 2.811

Region-enriched R2: 1.755/0.00003

CAV1 2.842 - - 0.964 - 0.935 0.943 Mlig455_030661 {REF} {Length: 1257} {Pfam: Caveolin [PF01146.19, score=124.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=105, Expect=2e-29]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=105, Expect=2e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=81.6, Expect=8e-20]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=144, Expect=1e-45]} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1310_31540, RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522} {RNA1509_52150, RNA1509_53381, RNA1509_6093, RNA1509_8522, RNA815_14585}
67. MligTC455_17806 20 0.42 Mlig455_044877

Neo: -

Age: -

2.841 - - 0.916 - 0.937 0.988 Mlig455_044877 {REF} {Length: 1723} {Pfam: F5/8 type C domain [PF00754.27, score=29.9]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [RH, Score=67.8, Expect=2e-14]} {RNA1310_72359} {RNA815_40265}
68. MligTC455_34614 24 0.5 Mlig455_060978

Neo: -

Age: -

2.841 - - 0.984 - 0.858 0.999 Mlig455_060978 {REF} {Length: 1770} {RNA1310_81929}
69. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 2.841 - - 0.959 - 0.916 0.966 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
70. MligTC455_31164 572 11.91 Mlig455_029609, Mlig455_045673

Neo: -

Age: -

2.841 - - 0.909 - 0.959 0.973

Mlig455_029609 {REF} {Length: 746} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=39.4]} {Smed: dd_Smed_v6_22533_0_1, dd_Smed_v6_22533_0_1, [Score=48.5, Expect=1e-06]} {RNA1310_96354} {RNA815_44390}

Mlig455_045673 {REF} {Length: 2025} {RNA1509_21720} {RNA1310_14760} {RNA815_24583}
71. MligTC455_26254 174 3.62 Mlig455_034978

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.366

Region-enriched R2: 5.463/0.00000

Regeneration-downregulated R4: -3.454

Regeneration-depleted R4: -3.454

FZD5 2.84 - - 0.985 - 0.865 0.990 Mlig455_034978 {REF} {Length: 3353} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=393.1]; Fz domain [PF01392.24, score=105.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=412, Expect=5e-137]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_49831} {RNA1310_28187} {RNA815_16996}
72. MligTC455_39097 57 1.18 Mlig455_051961

Neo: -

Age: -

Region-enriched R4: 5.550/0.02060

2.84 - - 0.973 - 0.876 0.991 Mlig455_051961 {REF} {Length: 1972} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=65.0]} {RNA1509_13138} {RNA1310_34740} {RNA815_15663}
73. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

2.838 - - 0.972 - 0.869 0.997 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
74. MligTC455_51119 47 0.99 Mlig455_021777, Mlig455_050835

Neo: -

Age: Up-Down-Down

HVCN1 2.837 - - 0.968 - 0.875 0.994

Mlig455_021777 {REF} {Length: 1306} {Human: ENSG00000122986, HVCN1, hydrogen voltage gated channel 1, [Score=47.4, Expect=1e-05]} {Mouse: ENSMUSG00000064267, Hvcn1, hydrogen voltage-gated channel 1, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_20053_0_1, dd_Smed_v6_20053_0_1, [Score=214, Expect=2e-65]} {RNA1310_72509} {RNA815_64339}

Mlig455_050835 {REF} {Length: 1720} {Pfam: Ion transport protein [PF00520.33, score=24.8]} {Human: ENSG00000122986, HVCN1, hydrogen voltage gated channel 1, [Score=65.9, Expect=2e-11]} {Mouse: ENSMUSG00000064267, Hvcn1, hydrogen voltage-gated channel 1, [Score=62.0, Expect=3e-10]} {Smed: dd_Smed_v6_20053_0_1, dd_Smed_v6_20053_0_1, [Score=308, Expect=7e-100]} {RNA1310_72509} {RNA815_64339}
75. MligTC455_39047 39 0.81 Mlig455_037921, Mlig455_038983

Neo: -

Age: -

TNN 2.836 - - 0.879 - 0.967 0.990

Mlig455_037921 {REF} {Length: 4077} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=111.9]} {Human: ENSG00000120332, TNN, tenascin N, [Score=95.5, Expect=1e-21]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=94.7, Expect=2e-21]} {Dmel: FBgn0050280, CG30280, [Score=87.0, Expect=3e-20]} {Celegans: WBGene00020516, T15B7.1, [Score=52.0, Expect=2e-07]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=73.6, Expect=1e-14]} {RNA1509_16377} {RNA1310_5710.1} {RNA815_14744.1}

Mlig455_038983 {REF} {Length: 2023} {RNA1310_108685} {RNA815_54007}
76. MligTC455_18506 59 1.23 Mlig455_038054

Neo: -

Age: Down-Up-Down

SP9 2.835 - - 0.953 - 0.893 0.989 Mlig455_038054 {REF} {Length: 3168} {Pfam: Zinc-finger double domain [PF13465.8, score=49.0]; Zinc finger, C2H2 type [PF00096.28, score=40.9]; C2H2-type zinc finger [PF13894.8, score=26.8]} {Human: ENSG00000217236, SP9, Sp9 transcription factor, [RH, Score=202, Expect=4e-59]; ENSG00000164651, SP8, Sp8 transcription factor, [RH, Score=202, Expect=5e-59]} {Mouse: ENSMUSG00000068859, Sp9, trans-acting transcription factor 9, [RH, Score=202, Expect=3e-59]; ENSMUSG00000048562, Sp8, trans-acting transcription factor 8, [RH, Score=201, Expect=9e-59]} {Dmel: FBgn0020378, Sp1, [RH, Score=198, Expect=6e-56]} {Celegans: WBGene00012735, sptf-3, SP (Specificity Protein) Transcription Factor, [Score=137, Expect=1e-35]} {Smed: dd_Smed_v6_17385_0_1, dd_Smed_v6_17385_0_1, [RH, Score=160, Expect=5e-46]} {RNA1310_42373}
77. MligTC455_40289 93 1.94 Mlig455_017727, Mlig455_056175

Neo: -

Age: -

BMP1, CUBN 2.835 - - 0.982 - 0.910 0.943

Mlig455_017727 {REF} {Length: 1202} {Pfam: CUB domain [PF00431.22, score=55.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=54.7, Expect=4e-08]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.0, Expect=3e-07]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=51.6, Expect=3e-07]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.4, Expect=2e-07]} {RNA1310_48745} {RNA815_23305}

Mlig455_056175 {REF} {Length: 2747} {Pfam: CUB domain [PF00431.22, score=62.6]} {Human: ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=52.8, Expect=2e-07]; ENSG00000107611, CUBN, cubilin, [Score=51.6, Expect=4e-07]} {Mouse: ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=51.6, Expect=3e-07]; ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=49.7, Expect=1e-06]} {Dmel: FBgn0003719, tld, tolloid, [Score=51.2, Expect=3e-07]} {Smed: dd_Smed_v6_69474_0_1, dd_Smed_v6_69474_0_1, [Score=47.0, Expect=3e-07]} {RNA1310_48745} {RNA815_23305}
78. MligTC455_16610 98 2.05 Mlig455_069894

Neo: -

Age: -

Region-enriched R2: 5.254/0.03136

WSCD2 2.831 - - 0.982 - 0.853 0.996 Mlig455_069894 {REF} {Length: 827} {Pfam: WSC domain [PF01822.21, score=59.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=47.8, Expect=9e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.4, Expect=2e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
79. MligTC455_24270 71 1.47 Mlig455_005120

Neo: -

Age: -

CHRNA7 2.83 - - 0.893 - 0.956 0.981 Mlig455_005120 {REF} {Length: 1530} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=115.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.6]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=148, Expect=4e-39]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=147, Expect=5e-39]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=146, Expect=2e-38]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=1e-36]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=135, Expect=5e-34]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=134, Expect=9e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=133, Expect=4e-34]} {RNA1509_43533} {RNA1310_20839.2} {RNA815_22406}
80. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

2.83 - - 0.903 - 0.974 0.953 Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
81. MligTC455_09697 52 1.08 Mlig455_009478, Mlig455_061921

Neo: -

Age: -

CD207 2.829 - - 0.944 - 0.892 0.993

Mlig455_009478 {REF} {Length: 1068} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Human: ENSG00000116031, CD207, CD207 molecule, [Score=48.5, Expect=5e-06]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=1e-13]} {RNA1310_33496.1} {RNA815_23317}

Mlig455_061921 {REF} {Length: 776} {Pfam: Lectin C-type domain [PF00059.23, score=35.3]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=69.7, Expect=4e-14]} {RNA1310_33496.1} {RNA815_23317}
82. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

2.827 - - 0.914 - 0.922 0.991

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
83. MligTC455_40118 72 1.5 Mlig455_001236

Neo: -

Age: -

KCNIP4 2.826 - - 0.937 - 0.930 0.959 Mlig455_001236 {REF} {Length: 1284} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=8e-33]} {RNA1310_43225} {RNA815_33406}
84. MligTC455_45495 988 20.58 Mlig455_010003

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R2: 2.517/0.00003

CAV2 2.826 - - 0.941 - 0.895 0.990 Mlig455_010003 {REF} {Length: 748} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1} {RNA815_31873}
85. MligTC455_18586 93 1.93 Mlig455_020226

Neo: -

Age: Down-Down-Up

2.825 - - 0.950 - 0.896 0.979 Mlig455_020226 {REF} {Length: 1261} {RNA1310_64121} {RNA815_32233}
86. MligTC455_50288 118 2.47 Mlig455_059182

Neo: -

Age: Up-Down-Down

2.824 - - 0.976 - 0.897 0.951 Mlig455_059182 {REF} {Length: 3438} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=42.6]; Lectin C-type domain [PF00059.23, score=23.6]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [RH, Score=189, Expect=3e-53]} {RNA1509_45950, RNA1509_54781} {RNA1310_10757.1, RNA1509_45950, RNA1509_54781} {RNA1509_45950, RNA1509_54781, RNA815_5369}
87. MligTC455_34115 6573 136.93 Mlig455_017846, Mlig455_047865

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.581

Region-enriched R2: 4.896/0.00130

2.821 - - 0.888 - 0.976 0.957

Mlig455_017846 {REF} {Length: 1260} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1310_63880, RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701, RNA815_12890.1}

Mlig455_047865 {REF} {Length: 1135} {RNA1509_4845} {RNA1310_63880} {RNA815_12890.1}
88. MligTC455_25858 48 1 Mlig455_005649, Mlig455_005698, Mlig455_008659

Neo: -

Age: -

2.82 - - 0.936 - 0.887 0.997

Mlig455_005649 {REF} {Length: 1060} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=27.0]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_005698 {REF} {Length: 1505} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=26.8]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_008659 {REF} {Length: 1151} {TRANSSPLICED} {Pfam: haloacid dehalogenase-like hydrolase [PF08282.14, score=19.9]} {RNA1509_25258} {RNA1310_56236} {RNA815_9496.1}
89. MligTC455_32311 54 1.12 Mlig455_026929

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.612

Region-enriched R2: 7.331/0.00256

2.817 - - 0.963 - 0.890 0.964 Mlig455_026929 {REF} {Length: 1796} {Pfam: PAN domain [PF00024.28, score=22.2]} {RNA1310_30037.1} {RNA815_37290}
90. MligTC455_52232 92 1.92 Mlig455_007894, Mlig455_008001

Neo: -

Age: logFC(26M/2M)=0.549

2.816 - - 0.916 - 0.904 0.996

Mlig455_007894 {REF} {Length: 1500} {RNA1310_22136} {RNA815_18832}

Mlig455_008001 {REF} {Length: 1450} {Pfam: PAN domain [PF00024.28, score=18.9]} {RNA1310_22136} {RNA815_18832}
91. MligTC455_37792 210 4.38 Mlig455_024774

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.926

Region-enriched R2: 6.055/0.00271

PKD1L2 2.815 - - 0.970 - 0.902 0.943 Mlig455_024774 {REF} {Length: 6374} {Pfam: Polycystin cation channel [PF08016.14, score=224.6]; PLAT/LH2 domain [PF01477.25, score=66.8]; Ion transport protein [PF00520.33, score=30.8]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=179, Expect=9e-45]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=187, Expect=3e-47]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=109, Expect=1e-23]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=187, Expect=2e-47]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [Score=902, Expect=0.0]} {RNA1509_46134} {RNA1310_488} {RNA815_1711}
92. MligTC455_41328 417 8.68 Mlig455_057091

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.162/0.00002

2.815 - - 0.832 - 0.995 0.988 Mlig455_057091 {REF} {Length: 854} {RNA1310_89414} {RNA815_40489.2}
93. MligTC455_52120 179 3.73 Mlig455_024423, Mlig455_024577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.068/0.01755

POU4F3 2.815 - - 0.952 - 0.912 0.951

Mlig455_024423 {REF} {Length: 1288} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}

Mlig455_024577 {REF} {Length: 1325} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}
94. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 2.809 - - 0.863 - 0.977 0.969 Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
95. MligTC455_40852 128 2.66 Mlig455_042301

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.671

Region-enriched R2: 6.158/0.00357

PKDREJ 2.806 - - 0.960 - 0.875 0.971 Mlig455_042301 {REF} {Length: 11184} {Pfam: Polycystin cation channel [PF08016.14, score=273.5]; PKD domain [PF00801.22, score=86.2]; PLAT/LH2 domain [PF01477.25, score=67.1]; REJ domain [PF02010.17, score=66.8]; PKD domain [PF18911.2, score=62.3]; Ion transport protein [PF00520.33, score=45.4]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=283, Expect=2e-75]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=273, Expect=2e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=158, Expect=3e-38]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=254, Expect=4e-67]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=514, Expect=2e-146]} {RNA1509_8046} {RNA1310_93, RNA1509_8046} {RNA1509_8046, RNA815_1216}
96. MligTC455_47905 56 1.16 Mlig455_037694

Neo: -

Age: -

2.806 - - 0.914 - 0.906 0.986 Mlig455_037694 {REF} {Length: 2503} {RNA1310_36768.1} {RNA815_27683}
97. MligTC455_47079 31 0.66 Mlig455_004459

Neo: -

Age: Up-Down-Down

SSUH2 2.805 - - 0.918 - 0.924 0.963 Mlig455_004459 {REF} {Length: 1975} {Pfam: DnaJ central domain [PF00684.21, score=20.3]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=8e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=89.7, Expect=1e-19]} {RNA1509_29510} {RNA1310_15488} {RNA815_5650}
98. MligTC455_52640 56 1.18 Mlig455_045103

Neo: -

Age: -

Region-enriched R2: 6.488/0.02940

2.805 - - 0.987 - 0.863 0.955 Mlig455_045103 {REF} {Length: 2443} {Pfam: F5/8 type C domain [PF00754.27, score=19.1]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}
99. MligTC455_40610 165 3.43 Mlig455_064484

Neo: -

Age: -

Region-enriched R2: 5.617/0.00105

2.805 - - 0.985 - 0.824 0.996 Mlig455_064484 {REF} {Length: 2931} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=24.9]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [Score=154, Expect=2e-40]} {RNA1509_26568} {RNA1310_9342.1, RNA1509_26568} {RNA1509_26568, RNA815_7018}
100. MligTC455_26765 686 14.29 Mlig455_006971

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.201/0.00046

2.804 - - 0.885 - 0.928 0.991 Mlig455_006971 {REF} {Length: 6360} {Pfam: Cadherin domain [PF00028.19, score=29.2]} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [RH, Score=328, Expect=1e-93]} {RNA1509_19813, RNA1509_5311} {RNA1310_621, RNA1509_19813, RNA1509_5311} {RNA1509_19813, RNA1509_5311, RNA815_183.1}

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