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Results for MligTC455_52640

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_52640 56 1.18 Mlig455_045103

Neo: -

Age: -

Region-enriched R2: 6.488/0.02940

Mlig455_045103 {REF} {Length: 2443} {Pfam: F5/8 type C domain [PF00754.27, score=19.1]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}

Cumulative graph for MligTC455_52640

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -3.949 1.562 0.99976 1.00000
RegionR2 6.488 1.562 0.00155 0.02940
RegionR3 1.627 1.562 0.29120 0.83355
RegionR4 -1.137 1.562 0.89502 1.00000
RegionR5 0.079 1.562 0.68392 1.00000
RegionR6 0.508 1.562 0.60283 1.00000
RegionR7 -1.801 1.562 1.00000 1.00000
RegionR8 -1.814 1.562 1.00000 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.824 1.562 0.99993 1.00000
RegenerationR2 -0.028 1.562 0.97287 1.00000
RegenerationR3 1.103 1.562 0.43293 0.82284
RegenerationR4 2.642 1.562 0.11598 0.52038
RegenerationR5 1.539 1.562 0.25381 0.68676
RegenerationR6 3.171 1.562 0.03281 0.22621
RegenerationBL -0.33 1.562 0.99972 1.00000
RegenerationTP 0.532 1.562 1.00000 1.00000


Genes with expression patterns similar to MligTC455_52640

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_52640 56 1.18 Mlig455_045103

Neo: -

Age: -

Region-enriched R2: 6.488/0.02940

4 1.000 - 1.000 - 1.000 1.000 Mlig455_045103 {REF} {Length: 2443} {Pfam: F5/8 type C domain [PF00754.27, score=19.1]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}
2. MligTC455_09455 51 1.06 Mlig455_029990

Neo: -

Age: -

Region-enriched R2: 4.710/0.00601

3.768 0.974 - 0.911 - 0.939 0.944 Mlig455_029990 {REF} {Length: 3817} {Mouse: ENSMUSG00000090546, Cdr1, cerebellar degeneration related antigen 1, [Score=63.2, Expect=8e-10]} {Celegans: WBGene00013762, Y113G7B.12, [Score=58.2, Expect=2e-08]} {RNA1509_44134} {RNA1310_28496} {RNA815_11143}
3. MligTC455_09697 52 1.08 Mlig455_009478, Mlig455_061921

Neo: -

Age: -

CD207 3.762 0.970 - 0.938 - 0.892 0.962

Mlig455_009478 {REF} {Length: 1068} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Human: ENSG00000116031, CD207, CD207 molecule, [Score=48.5, Expect=5e-06]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=1e-13]} {RNA1310_33496.1} {RNA815_23317}

Mlig455_061921 {REF} {Length: 776} {Pfam: Lectin C-type domain [PF00059.23, score=35.3]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=69.7, Expect=4e-14]} {RNA1310_33496.1} {RNA815_23317}
4. MligTC455_09456 47 0.97 Mlig455_029993

Neo: -

Age: -

Region-enriched R2: 5.041/0.00960

3.757 0.974 - 0.984 - 0.853 0.946 Mlig455_029993 {REF} {Length: 3167} {RNA1509_44134} {RNA1310_31411} {RNA815_45870}
5. MligTC455_50253 44 0.92 Mlig455_031495

Neo: -

Age: -

GABRB2 3.737 0.987 - 0.969 - 0.825 0.956 Mlig455_031495 {REF} {Length: 2129} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=58.3]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [Score=71.2, Expect=6e-14]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [Score=67.8, Expect=1e-12]; ENSMUSG00000029212, Gabrb1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, [Score=67.4, Expect=1e-12]} {Dmel: FBgn0024963, GluClalpha, [Score=54.3, Expect=3e-08]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=70.1, Expect=9e-14]} {RNA1310_46931} {RNA815_25428}
6. MligTC455_43581 177 3.68 Mlig455_042725, Mlig455_042827, Mlig455_063146

Neo: -

Age: Up-Down-Down

GRIA2 3.736 0.979 - 0.950 - 0.821 0.986

Mlig455_042725 {REF} {Length: 3074} {Pfam: Ligand-gated ion channel [PF00060.28, score=104.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.7]; Receptor family ligand binding region [PF01094.30, score=33.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=153, Expect=1e-37]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=149, Expect=2e-36]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=147, Expect=7e-36]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=152, Expect=2e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=148, Expect=3e-36]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=147, Expect=8e-36]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=2e-35]} {Dmel: FBgn0038837, CG3822, [Score=140, Expect=5e-34]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=253, Expect=2e-76]} {RNA1310_25150} {RNA815_13942}

Mlig455_042827 {REF} {Length: 2869} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.9]; Receptor family ligand binding region [PF01094.30, score=49.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.3]; Iron-containing alcohol dehydrogenase [PF13685.8, score=18.6]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=125, Expect=6e-29]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=122, Expect=5e-28]; ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=121, Expect=7e-28]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=120, Expect=2e-27]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=125, Expect=5e-29]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=122, Expect=4e-28]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=121, Expect=1e-27]; ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=120, Expect=1e-27]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=119, Expect=3e-27]} {Dmel: FBgn0039927, CG11155, [Score=127, Expect=7e-30]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=217, Expect=2e-63]} {RNA1310_25150} {RNA815_13942}

Mlig455_063146 {REF} {Length: 2444} {Pfam: Receptor family ligand binding region [PF01094.30, score=35.8]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=82.4, Expect=1e-16]} {RNA1310_25150} {RNA815_13999}
7. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

3.72 0.940 - 0.977 - 0.846 0.957 Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
8. MligTC455_26255 126 2.63 Mlig455_053706

Neo: -

Age: Up-Down-Down

Region-enriched R2: 6.424/0.00107
Region-enriched R4: 3.360/0.04239

FZD5 3.717 0.918 - 0.994 - 0.841 0.964 Mlig455_053706 {REF} {Length: 3671} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=393.1]; Fz domain [PF01392.24, score=105.2]} {Human: ENSG00000163251, FZD5, frizzled class receptor 5, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000045005, Fzd5, frizzled class receptor 5, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0016797, fz2, frizzled 2, [RH, Score=562, Expect=0.0]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [RH, Score=412, Expect=5e-137]} {Smed: dd_Smed_v6_11823_0_1, dd_Smed_v6_11823_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_49831} {RNA1310_28187, RNA1509_49831} {RNA1509_49831, RNA815_16996}
9. MligTC455_39890 162 3.37 Mlig455_047281, Mlig455_047331, Mlig455_069333

Neo: -

Age: -

Region-enriched R2: 6.097/0.00148

PLSCR1 3.701 0.989 - 0.953 - 0.802 0.957

Mlig455_047281 {REF} {Length: 1404} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_047331 {REF} {Length: 1395} {Pfam: Scramblase [PF03803.17, score=248.1]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=225, Expect=4e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=227, Expect=5e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=222, Expect=3e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=223, Expect=6e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=2e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=306, Expect=1e-104]} {RNA1310_29769} {RNA815_41335}

Mlig455_069333 {REF} {Length: 1416} {Pfam: Scramblase [PF03803.17, score=248.7]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=226, Expect=1e-72]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=228, Expect=2e-73]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=223, Expect=1e-71]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=224, Expect=2e-73]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=194, Expect=4e-61]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=304, Expect=2e-103]} {RNA1310_29769} {RNA815_41335}
10. MligTC455_04786 26 0.55 Mlig455_043817, Mlig455_047431

Neo: -

Age: -

3.7 0.991 - 0.946 - 0.808 0.955

Mlig455_043817 {REF} {Length: 319} {NoTransDecoderORF} {RNA1310_64690}

Mlig455_047431 {REF} {Length: 2194} {Pfam: Glycine rich protein [PF12810.9, score=25.3]} {RNA1509_16377} {RNA1310_33363.2} {RNA815_25152}
11. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

3.687 0.982 - 0.933 - 0.813 0.959 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
12. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 3.67 0.954 - 0.955 - 0.830 0.931 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
13. MligTC455_34499 65 1.36 Mlig455_025160, Mlig455_063937

Neo: -

Age: -

3.664 0.984 - 0.965 - 0.758 0.957

Mlig455_025160 {REF} {Length: 942} {RNA1310_54940} {RNA815_33690.1}

Mlig455_063937 {REF} {Length: 995} {RNA1310_54940} {RNA815_33690.1}
14. MligTC455_44646 193 4.01 Mlig455_013515

Neo: -

Age: Down-Up-Down

SCNN1B 3.659 0.962 - 0.936 - 0.852 0.909 Mlig455_013515 {REF} {Length: 2272} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=308.7]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [RH, Score=191, Expect=3e-52]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [RH, Score=188, Expect=3e-51]} {Dmel: FBgn0030795, ppk28, pickpocket 28, [Score=68.2, Expect=1e-11]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=143, Expect=2e-36]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=175, Expect=2e-47]} {RNA1509_52917} {RNA1310_12013.1, RNA1509_52917} {RNA1509_52917, RNA815_4777}
15. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 3.611 0.944 - 0.976 - 0.773 0.918 Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
16. MligTC455_33040 203 4.23 Mlig455_032497

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R2: 4.005/0.00408

PKD2L1 3.611 0.935 - 0.977 - 0.776 0.923 Mlig455_032497 {REF} {Length: 3318} {Pfam: Polycystin cation channel [PF08016.14, score=293.1]; Ion transport protein [PF00520.33, score=39.7]} {Human: ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [Score=236, Expect=4e-66]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=261, Expect=3e-73]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=131, Expect=5e-31]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=180, Expect=1e-47]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=641, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
17. MligTC455_42376 61 1.27 Mlig455_069890

Neo: -

Age: -

3.581 0.849 - 0.961 - 0.828 0.943 Mlig455_069890 {REF} {Length: 630} {TRANSSPLICED} {Pfam: PAN domain [PF00024.28, score=26.1]} {RNA1509_53783} {RNA1310_37190} {RNA815_24434}
18. MligTC455_18499 24 0.5 Mlig455_012628

Neo: -

Age: -

3.58 0.992 - 0.918 - 0.756 0.914 Mlig455_012628 {REF} {Length: 1340} {Smed: dd_Smed_v6_500_0_1, dd_Smed_v6_500_0_1, [Score=60.5, Expect=1e-10]} {RNA1310_107419} {RNA815_46554}
19. MligTC455_42510 125 2.6 Mlig455_025998, Mlig455_070424

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.702

3.577 0.807 - 0.972 - 0.846 0.952

Mlig455_025998 {REF} {Length: 1369} {RNA1310_73875.1}

Mlig455_070424 {REF} {Length: 1082} {RNA1310_73875.1}
20. MligTC455_52393 60 1.25 Mlig455_039640

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.560

Region-enriched R2: 5.399/0.01138

CHAT 3.576 0.950 - 0.995 - 0.704 0.927 Mlig455_039640 {REF} {Length: 3681} {TRANSSPLICED} {Pfam: Choline/Carnitine o-acyltransferase [PF00755.22, score=546.9]} {Human: ENSG00000070748, CHAT, choline O-acetyltransferase, [RH, Score=520, Expect=1e-176]} {Mouse: ENSMUSG00000021919, Chat, choline acetyltransferase, [RH, Score=521, Expect=3e-177]} {Dmel: FBgn0000303, ChAT, Choline acetyltransferase, [Score=452, Expect=1e-149]} {Celegans: WBGene00000481, cha-1, Choline O-acetyltransferase, [RH, Score=356, Expect=1e-113]} {Smed: dd_Smed_v6_6208_0_1, dd_Smed_v6_6208_0_1, [Score=535, Expect=0.0]} {RNA1509_40088} {RNA1310_20833} {RNA815_26395}
21. MligTC455_40852 128 2.66 Mlig455_042301

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.671

Region-enriched R2: 6.158/0.00357

PKDREJ 3.557 0.848 - 0.965 - 0.827 0.917 Mlig455_042301 {REF} {Length: 11184} {Pfam: Polycystin cation channel [PF08016.14, score=273.5]; PKD domain [PF00801.22, score=86.2]; PLAT/LH2 domain [PF01477.25, score=67.1]; REJ domain [PF02010.17, score=66.8]; PKD domain [PF18911.2, score=62.3]; Ion transport protein [PF00520.33, score=45.4]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=283, Expect=2e-75]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=273, Expect=2e-72]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=158, Expect=3e-38]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=254, Expect=4e-67]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [Score=514, Expect=2e-146]} {RNA1509_8046} {RNA1310_93, RNA1509_8046} {RNA1509_8046, RNA815_1216}
22. MligTC455_34655 89 1.86 Mlig455_058020, Mlig455_058176

Neo: -

Age: -

Region-enriched R2: 5.798/0.00826

PPEF1 3.555 0.869 - 0.797 - 0.936 0.953

Mlig455_058020 {REF} {Length: 3007} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=84.9]; EF-hand domain pair [PF13499.8, score=77.8]; EF hand [PF00036.34, score=66.0]; EF-hand domain pair [PF13833.8, score=52.1]; EF-hand domain [PF13405.8, score=48.4]; EF hand [PF13202.8, score=38.2]; PPP5 TPR repeat region [PF08321.14, score=37.0]; EF-hand domain [PF14658.8, score=23.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.4]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [Score=416, Expect=2e-138]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [Score=413, Expect=9e-138]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [Score=404, Expect=3e-134]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [Score=455, Expect=2e-155]} {Smed: dd_Smed_v6_11874_0_2, dd_Smed_v6_11874_0_2, [Score=516, Expect=2e-178]} {RNA1509_3508} {RNA1310_10928.2} {RNA815_11707}

Mlig455_058176 {REF} {Length: 3371} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=102.6]; EF-hand domain pair [PF13499.8, score=72.6]; EF hand [PF00036.34, score=64.2]; EF-hand domain pair [PF13833.8, score=51.3]; EF-hand domain [PF13405.8, score=46.1]; EF hand [PF13202.8, score=36.7]; PPP5 TPR repeat region [PF08321.14, score=36.6]; EF-hand domain [PF14658.8, score=26.5]; IQ calmodulin-binding motif [PF00612.29, score=21.3]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=19.8]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [RH, Score=546, Expect=0.0]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [Score=520, Expect=3e-177]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [Score=529, Expect=2e-180]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [Score=598, Expect=0.0]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [Score=671, Expect=0.0]} {RNA1509_3508} {RNA1310_10928.2} {RNA815_11707}
23. MligTC455_45350 92 1.93 Mlig455_024760, Mlig455_058317, Mlig455_068656

Neo: -

Age: Up-Down-Down

SLC17A6, SLC17A8 3.544 0.924 - 0.940 - 0.714 0.966

Mlig455_024760 {REF} {Length: 2935} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_058317 {REF} {Length: 2971} {Pfam: Major Facilitator Superfamily [PF07690.18, score=157.7]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=534, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=521, Expect=8e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=531, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=526, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=485, Expect=1e-164]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [Score=474, Expect=7e-162]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [Score=585, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_068656 {REF} {Length: 3034} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}
24. MligTC455_21755 70 1.47 Mlig455_021213

Neo: -

Age: -

3.53 0.920 - 0.865 - 0.791 0.954 Mlig455_021213 {REF} {Length: 4215} {Pfam: F5/8 type C domain [PF00754.27, score=55.5]} {RNA1509_2515} {RNA1310_33166} {RNA815_14716}
25. MligTC455_23621 323 6.72 Mlig455_039694, Mlig455_039749

Neo: -

Age: -

Region-enriched R2: 2.235/0.02499

3.522 0.876 - 0.869 - 0.812 0.965

Mlig455_039694 {REF} {Length: 2054} {RNA1509_29694} {RNA1310_14789} {RNA815_12997}

Mlig455_039749 {REF} {Length: 1751} {RNA1509_29694} {RNA1310_14789, RNA1509_29694} {RNA1509_29694, RNA815_12997}
26. MligTC455_49334 86 1.78 Mlig455_037751

Neo: -

Age: -

3.498 0.976 - 0.778 - 0.787 0.957 Mlig455_037751 {REF} {Length: 708} {RNA1509_25826} {RNA1310_47741} {RNA815_23874}
27. MligTC455_34369 112 2.34 Mlig455_015308, Mlig455_015354, Mlig455_036248, Mlig455_068737, Mlig455_070110

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.462/0.00546

3.483 0.963 - 0.994 - 0.727 0.799

Mlig455_015308 {REF} {Length: 1459} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.9]} {RNA1310_34740} {RNA815_15663}

Mlig455_015354 {REF} {Length: 1446} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=66.3]; Sialidase, N-terminal domain [PF02973.18, score=18.5]} {RNA1310_34740} {RNA815_15663}

Mlig455_036248 {REF} {Length: 2111} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=120.9]; Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=28.5]; PAN domain [PF00024.28, score=19.9]} {RNA1509_45496} {RNA1310_2539.1} {RNA815_252.1}

Mlig455_068737 {REF} {Length: 1096} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=68.3]; Sialidase, N-terminal domain [PF02973.18, score=19.9]} {RNA1310_34740} {RNA815_37905}

Mlig455_070110 {REF} {Length: 1340} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=109.6]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1}
28. MligTC455_16875 42 0.88 Mlig455_028243

Neo: -

Age: Up-Down-Down

KCNK16 3.482 0.988 - 0.789 - 0.813 0.892 Mlig455_028243 {REF} {Length: 2676} {Pfam: Ion channel [PF07885.18, score=116.8]; Ion transport protein [PF00520.33, score=28.8]; Protein of unknown function (DUF3112) [PF11309.10, score=19.5]} {Human: ENSG00000095981, KCNK16, potassium two pore domain channel subfamily K member 16, [Score=97.8, Expect=5e-22]; ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=97.4, Expect=2e-21]; ENSG00000100433, KCNK10, potassium two pore domain channel subfamily K member 10, [Score=94.4, Expect=6e-20]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=102, Expect=4e-23]; ENSMUSG00000023387, Kcnk16, potassium channel, subfamily K, member 16, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0033257, sand, sandman, [Score=150, Expect=2e-40]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=162, Expect=5e-45]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=340, Expect=2e-113]} {RNA1509_39975} {RNA1310_18301.1, RNA1509_39975} {RNA1509_39975, RNA815_12440}
29. MligTC455_49491 136 2.83 Mlig455_054796

Neo: -

Age: -

Region-enriched R2: 7.065/0.00003

3.474 0.713 - 0.984 - 0.820 0.957 Mlig455_054796 {REF} {Length: 1567} {RNA1509_22234} {RNA1310_23973} {RNA815_10832}
30. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 3.463 0.842 - 0.945 - 0.720 0.956 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
31. MligTC455_19030 628 13.08 Mlig455_046052

Neo: -

Age: -

Region-enriched R2: 3.353/0.00000

ADGRL3 3.461 0.921 - 0.809 - 0.761 0.970 Mlig455_046052 {REF} {Length: 7405} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=104.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=61.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=54.3]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=28.0]} {Human: ENSG00000150471, ADGRL3, adhesion G protein-coupled receptor L3, [Score=157, Expect=8e-38]} {Mouse: ENSMUSG00000037605, Adgrl3, adhesion G protein-coupled receptor L3, [Score=158, Expect=5e-38]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=72.4, Expect=5e-12]} {Celegans: WBGene00002251, lat-1, Latrophilin-like protein 1, [Score=107, Expect=5e-23]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=587, Expect=1e-173]} {RNA1509_17130, RNA1509_4023, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1310_254.2, RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867, RNA815_85.1}
32. MligTC455_13095 40 0.82 Mlig455_036239

Neo: -

Age: -

3.442 0.957 - 0.873 - 0.844 0.768 Mlig455_036239 {REF} {Length: 2786} {RNA1509_41201} {RNA1310_51044} {RNA815_51130}
33. MligTC455_35895 102 2.12 Mlig455_063971

Neo: -

Age: -

RYK 3.434 0.963 - 0.810 - 0.743 0.918 Mlig455_063971 {REF} {Length: 3496} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=209.4]; WIF domain [PF02019.20, score=109.7]; Protein kinase domain [PF00069.27, score=79.1]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=1e-55]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [RH, Score=202, Expect=2e-55]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=239, Expect=4e-69]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_12594_0_2, dd_Smed_v6_12594_0_2, [Score=201, Expect=3e-55]} {RNA1509_58811} {RNA1310_6671.2} {RNA815_41921}
34. MligTC455_40352 49 1.03 Mlig455_024410

Neo: -

Age: -

3.425 0.743 - 0.886 - 0.825 0.971 Mlig455_024410 {REF} {Length: 1509} {TRANSSPLICED} {RNA1310_29008} {RNA815_41596}
35. MligTC455_21693 48 1 Mlig455_024307, Mlig455_024362, Mlig455_024476

Neo: -

Age: -

AHR 3.394 0.952 - 0.802 - 0.721 0.919

Mlig455_024307 {REF} {Length: 4440} {Pfam: PAS fold [PF08447.14, score=59.6]; PAS fold [PF00989.27, score=42.5]; PAS domain [PF14598.8, score=40.5]; PAS domain [PF13426.9, score=18.9]; C-terminal region of eIF3h [PF19445.1, score=18.6]} {Human: ENSG00000106546, AHR, aryl hydrocarbon receptor, [Score=229, Expect=8e-64]; ENSG00000283321, AC019117.2, novel protein, [Score=228, Expect=1e-63]} {Mouse: ENSMUSG00000019256, Ahr, aryl-hydrocarbon receptor, [Score=216, Expect=2e-59]} {Dmel: FBgn0003513, ss, spineless, [Score=303, Expect=7e-91]} {Celegans: WBGene00000096, ahr-1, Aryl hydrocarbon receptor protein 1, [Score=200, Expect=8e-56]} {Smed: dd_Smed_v6_17534_0_1, dd_Smed_v6_17534_0_1, [Score=369, Expect=4e-118]} {RNA1310_45588}

Mlig455_024362 {REF} {Length: 4404} {Pfam: PAS fold [PF08447.14, score=59.5]; PAS fold [PF00989.27, score=43.6]; PAS domain [PF14598.8, score=41.4]; Helix-loop-helix DNA-binding domain [PF00010.28, score=27.4]; C-terminal region of eIF3h [PF19445.1, score=20.1]} {Human: ENSG00000106546, AHR, aryl hydrocarbon receptor, [RH, Score=298, Expect=1e-88]; ENSG00000283321, AC019117.2, novel protein, [RH, Score=297, Expect=2e-88]} {Mouse: ENSMUSG00000019256, Ahr, aryl-hydrocarbon receptor, [RH, Score=286, Expect=2e-84]} {Dmel: FBgn0003513, ss, spineless, [RH, Score=398, Expect=1e-124]} {Celegans: WBGene00000096, ahr-1, Aryl hydrocarbon receptor protein 1, [RH, Score=265, Expect=6e-79]} {Smed: dd_Smed_v6_17534_0_1, dd_Smed_v6_17534_0_1, [RH, Score=503, Expect=4e-169]} {RNA1310_45588}

Mlig455_024476 {REF} {Length: 4767} {Pfam: PAS fold [PF08447.14, score=58.8]; PAS fold [PF00989.27, score=41.6]; PAS domain [PF14598.8, score=40.1]; Helix-loop-helix DNA-binding domain [PF00010.28, score=27.1]} {Human: ENSG00000106546, AHR, aryl hydrocarbon receptor, [Score=230, Expect=4e-63]; ENSG00000283321, AC019117.2, novel protein, [Score=229, Expect=4e-63]} {Mouse: ENSMUSG00000019256, Ahr, aryl-hydrocarbon receptor, [Score=217, Expect=8e-59]} {Dmel: FBgn0003513, ss, spineless, [Score=303, Expect=5e-89]} {Celegans: WBGene00000096, ahr-1, Aryl hydrocarbon receptor protein 1, [Score=199, Expect=1e-54]} {Smed: dd_Smed_v6_17534_0_1, dd_Smed_v6_17534_0_1, [Score=373, Expect=3e-117]} {RNA1310_45588}
36. MligTC455_48522 94 1.96 Mlig455_032491

Neo: -

Age: -

Region-enriched R2: 4.888/0.01251

3.39 0.974 - 0.807 - 0.706 0.903 Mlig455_032491 {REF} {Length: 2169} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=47.3]} {Dmel: FBgn0015776, nrv1, nervana 1, [Score=55.5, Expect=2e-08]} {RNA1310_12303} {RNA815_10417}
37. MligTC455_52656 121 2.51 Mlig455_062381, Mlig455_062408

Neo: -

Age: Down-Up-Down

3.388 0.983 - 0.709 - 0.781 0.915

Mlig455_062381 {REF} {Length: 2245} {RNA1310_26272} {RNA815_22826}

Mlig455_062408 {REF} {Length: 2277} {RNA1310_26272} {RNA815_37592}
38. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

3.339 0.719 - 0.877 - 0.793 0.950 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
39. MligTC455_19709 221 4.6 Mlig455_010385

Neo: -

Age: -

Region-enriched R2: 4.689/0.03280

3.301 0.991 - 0.761 - 0.822 0.727 Mlig455_010385 {REF} {Length: 903} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.2]} {RNA1509_54211} {RNA1310_54505.2} {RNA815_29389}
40. MligTC455_53842 1222 25.46 Mlig455_023890

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.345

Region-enriched R2: 1.546/0.01667

3.281 0.723 - 0.805 - 0.800 0.953 Mlig455_023890 {REF} {Length: 1336} {RNA1509_15580} {RNA1310_22487.1} {RNA815_10676.1}
41. MligTC455_49877 188 3.91 Mlig455_027465

Neo: -

Age: -

Region-enriched R2: 3.005/0.04141

AC254952.1 3.202 0.750 - 0.735 - 0.747 0.970 Mlig455_027465 {REF} {Length: 2059} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=89.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.0]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=6e-38]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=144, Expect=9e-38]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=141, Expect=2e-36]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=1e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=6e-37]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=139, Expect=5e-36]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=134, Expect=2e-34]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=132, Expect=4e-33]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=126, Expect=6e-32]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=131, Expect=2e-33]} {RNA1310_26175} {RNA815_7952}
42. MligTC455_38950 23 0.47 Mlig455_065213

Neo: -

Age: -

2.948 0.991 - 1.000 - - 0.957 Mlig455_065213 {REF} {Length: 567} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839} {RNA815_35329}
43. MligTC455_39222 213 4.44 Mlig455_064653, Mlig455_064686

Neo: -

Age: -

Region-enriched R2: 4.317/0.00597

2.945 0.988 - 0.992 - - 0.965

Mlig455_064653 {REF} {Length: 2836} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.9, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=7e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_56255} {RNA1310_13407} {RNA815_38407}

Mlig455_064686 {REF} {Length: 3820} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.8]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=58.5, Expect=6e-09]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=73.6, Expect=8e-14]} {Celegans: WBGene00008885, F16C3.1, [Score=51.2, Expect=8e-07]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=219, Expect=1e-66]} {RNA1509_50956} {RNA1310_13407} {RNA815_38407}
44. MligTC455_52570 71 1.49 Mlig455_066071

Neo: -

Age: Up-Down-Up

2.941 0.991 - 0.993 - - 0.957 Mlig455_066071 {REF} {Length: 2575} {Pfam: Hemingway/CFA97 [PF13879.8, score=54.6]; Annexin [PF00191.22, score=26.1]} {Mouse: ENSMUSG00000090336, Cfap97d2, CFAP97 domain containing 2, [Score=46.6, Expect=3e-06]} {Smed: dd_Smed_v6_2676_0_1, dd_Smed_v6_2676_0_1, [Score=70.1, Expect=2e-13]} {RNA1310_29320.1} {RNA815_54680}
45. MligTC455_17177 103 2.15 Mlig455_048992, Mlig455_049009

Neo: -

Age: Down-Down-Up

2.94 0.992 - 0.991 - - 0.957

Mlig455_048992 {REF} {Length: 1836} {RNA1509_44702} {RNA1310_14743, RNA1509_44702} {RNA1509_44702, RNA815_20669.1}

Mlig455_049009 {REF} {Length: 1823} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
46. MligTC455_38949 105 2.19 Mlig455_065209

Neo: -

Age: -

Region-specific R2: 7.633

Region-enriched R2: 10.088/0.00000

2.938 0.990 - 0.991 - - 0.957 Mlig455_065209 {REF} {Length: 591} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839, RNA1509_44618} {RNA1509_44618, RNA815_35329}
47. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 2.913 0.962 - 0.974 - - 0.977 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
48. MligTC455_17178 54 1.12 Mlig455_067758

Neo: -

Age: -

Region-enriched R2: 7.471/0.00007

2.911 0.994 - 0.977 - - 0.940 Mlig455_067758 {REF} {Length: 2301} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
49. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

2.908 0.986 - 0.963 - - 0.959

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
50. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

2.901 0.968 - 0.975 - - 0.958 Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
51. MligTC455_17021 49 1.02 Mlig455_030263

Neo: -

Age: -

2.896 0.979 - 0.977 - - 0.940 Mlig455_030263 {REF} {Length: 566} {TRANSSPLICED} {Pfam: Galactosyltransferase [PF01762.23, score=23.7]} {Dmel: FBgn0000221, brn, brainiac, [Score=45.8, Expect=1e-06]} {RNA1310_35735} {RNA815_59866}
52. MligTC455_43979 188 3.92 Mlig455_000082, Mlig455_063749

Neo: -

Age: -

GHSR 2.891 0.991 - 0.944 - - 0.956

Mlig455_000082 {REF} {Length: 1342} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=53.1]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=18.2]} {Human: ENSG00000121853, GHSR, growth hormone secretagogue receptor, [Score=52.0, Expect=7e-07]} {Mouse: ENSMUSG00000051136, Ghsr, growth hormone secretagogue receptor, [Score=50.4, Expect=2e-06]} {Celegans: WBGene00018798, gnrr-1, GoNadotropin-Releasing hormone Receptor (GnRHR) related, [Score=48.9, Expect=3e-06]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=160, Expect=9e-47]} {RNA1310_30553}

Mlig455_063749 {REF} {Length: 1323} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.4]} {Smed: dd_Smed_v6_60346_0_1, dd_Smed_v6_60346_0_1, [RH, Score=157, Expect=1e-45]} {RNA1310_30553}
53. MligTC455_34525 52 1.08 Mlig455_021566

Neo: -

Age: Down-Up-Down

GNAI1 2.889 0.989 - 0.949 - - 0.951 Mlig455_021566 {REF} {Length: 3532} {Pfam: G-protein alpha subunit [PF00503.22, score=404.9]; ADP-ribosylation factor family [PF00025.23, score=56.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=20.1]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.4]} {Human: ENSG00000127955, GNAI1, G protein subunit alpha i1, [Score=486, Expect=2e-171]; ENSG00000114353, GNAI2, G protein subunit alpha i2, [Score=481, Expect=3e-169]; ENSG00000065135, GNAI3, G protein subunit alpha i3, [Score=474, Expect=1e-166]} {Mouse: ENSMUSG00000057614, Gnai1, guanine nucleotide binding protein (G protein), alpha inhibiting 1, [Score=486, Expect=2e-171]; ENSMUSG00000032562, Gnai2, guanine nucleotide binding protein (G protein), alpha inhibiting 2, [Score=475, Expect=5e-167]; ENSMUSG00000000001, Gnai3, guanine nucleotide binding protein (G protein), alpha inhibiting 3, [Score=474, Expect=1e-166]} {Dmel: FBgn0001104, Galphai, G protein alpha i subunit, [Score=468, Expect=2e-164]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [Score=446, Expect=5e-156]} {Smed: dd_Smed_v6_12112_0_1, dd_Smed_v6_12112_0_1, [RH, Score=598, Expect=0.0]} {RNA1509_45426} {RNA1310_26920, RNA1509_45426} {RNA1509_45426, RNA815_11718}
54. MligTC455_27313 61 1.27 Mlig455_031814, Mlig455_047613

Neo: -

Age: -

WSCD2 2.879 0.991 - 0.924 - - 0.964

Mlig455_031814 {REF} {Length: 844} {Pfam: WSC domain [PF01822.21, score=66.1]; PAN domain [PF00024.28, score=19.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=62.0, Expect=7e-11]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=60.5, Expect=1e-10]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=56.6, Expect=3e-09]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=48.5, Expect=1e-06]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}

Mlig455_047613 {REF} {Length: 843} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.0, Expect=5e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=48.9, Expect=4e-07]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}
55. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

PPA1 2.878 0.991 - 0.933 - - 0.954 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
56. MligTC455_31163 72 1.51 Mlig455_045625

Neo: -

Age: Up-Down-Down

2.869 0.964 - 0.974 - - 0.931 Mlig455_045625 {REF} {Length: 1957} {RNA1509_21720} {RNA1310_14760, RNA1509_21720} {RNA1509_21720, RNA815_24583}
57. MligTC455_15949 37 0.76 Mlig455_059880

Neo: -

Age: -

2.865 0.968 - 0.976 - - 0.921 Mlig455_059880 {REF} {Length: 1226} {Pfam: Lectin C-type domain [PF00059.23, score=39.5]} {Dmel: FBgn0031373, CG15358, [Score=52.8, Expect=4e-08]} {RNA1310_120903}
58. MligTC455_13963 31 0.64 Mlig455_052027

Neo: -

Age: Down-Up-Down

2.864 0.991 - 0.916 - - 0.957 Mlig455_052027 {REF} {Length: 1717} {RNA1509_48973} {RNA1310_34931} {RNA815_59614}
59. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

2.859 0.965 - 0.986 - - 0.908

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
60. MligTC455_51334 326 6.78 Mlig455_011442, Mlig455_061180

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.828

2.859 0.934 - 0.962 - - 0.963

Mlig455_011442 {REF} {Length: 742} {RNA1310_57576.1} {RNA815_29867}

Mlig455_061180 {REF} {Length: 769} {RNA1310_57576.1} {RNA815_29867}
61. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

2.857 0.991 - 0.915 - - 0.951 Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
62. MligTC455_38162 710 14.8 Mlig455_045004

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.269

Region-enriched R2: 5.838/0.00000

Regeneration-downregulated R2: -4.412

Regeneration-depleted R2: -4.412

2.849 0.948 - 0.938 - - 0.963 Mlig455_045004 {REF} {Length: 659} {Smed: dd_Smed_v6_4046_0_1, dd_Smed_v6_4046_0_1, [Score=57.8, Expect=2e-12]} {RNA1509_50998, RNA1509_57106} {RNA1310_56015, RNA1509_50998, RNA1509_57106} {RNA1509_50998, RNA1509_57106, RNA815_29915}
63. MligTC455_35701 66 1.37 Mlig455_010067, Mlig455_063254, Mlig455_063279

Neo: -

Age: Up-Down-Down

Region-enriched R2: 4.716/0.02468

2.846 0.942 - 0.961 - - 0.943

Mlig455_010067 {REF} {Length: 2624} {Pfam: Polycystin cation channel [PF08016.14, score=46.7]} {RNA1310_62521}

Mlig455_063254 {REF} {Length: 2738} {Pfam: Polycystin cation channel [PF08016.14, score=43.3]; Lipopolysaccharide assembly protein A domain [PF06305.13, score=18.4]} {RNA1509_7418} {RNA1310_62521} {RNA815_3659}

Mlig455_063279 {REF} {Length: 2677} {Pfam: Polycystin cation channel [PF08016.14, score=46.0]} {RNA1310_62521}
64. MligTC455_42664 24 0.5 Mlig455_025689

Neo: -

Age: Up-Down-Down

2.845 0.919 - 0.982 - - 0.944 Mlig455_025689 {REF} {Length: 2068} {RNA1310_32888}
65. MligTC455_46691 41 0.85 Mlig455_018781, Mlig455_018951

Neo: -

Age: Up-Down-Down

2.84 0.910 - 0.964 - - 0.966

Mlig455_018781 {REF} {Length: 1694} {Celegans: WBGene00021142, clec-133, C-type LECtin, [RH, Score=52.0, Expect=6e-08]} {RNA1310_43489} {RNA815_41340}

Mlig455_018951 {REF} {Length: 2466} {Celegans: WBGene00021142, clec-133, C-type LECtin, [RH, Score=52.0, Expect=6e-08]} {RNA1310_38733.1} {RNA815_41340}
66. MligTC455_12102 59 1.23 Mlig455_041538, Mlig455_053099

Neo: -

Age: -

Region-enriched R2: 6.626/0.00371

DEGS2 2.835 0.986 - 0.902 - - 0.947

Mlig455_041538 {REF} {Length: 1966} {Pfam: Fatty acid desaturase [PF00487.26, score=87.9]; Sphingolipid Delta4-desaturase (DES) [PF08557.12, score=57.6]} {Human: ENSG00000168350, DEGS2, delta 4-desaturase, sphingolipid 2, [Score=319, Expect=2e-107]; ENSG00000143753, DEGS1, delta 4-desaturase, sphingolipid 1, [Score=315, Expect=5e-106]} {Mouse: ENSMUSG00000038633, Degs1, delta(4)-desaturase, sphingolipid 1, [Score=308, Expect=2e-103]; ENSMUSG00000021263, Degs2, delta(4)-desaturase, sphingolipid 2, [Score=307, Expect=6e-103]} {Dmel: FBgn0001941, ifc, infertile crescent, [Score=345, Expect=5e-118]} {Celegans: WBGene00017996, F33D4.4, Putative sphingolipid delta(4)-desaturase, [Score=318, Expect=4e-107]} {Smed: dd_Smed_v6_7414_0_1, dd_Smed_v6_7414_0_1, [RH, Score=409, Expect=7e-143]} {RNA1310_20672.2} {RNA815_19986}

Mlig455_053099 {REF} {Length: 2009} {Pfam: Fatty acid desaturase [PF00487.26, score=87.9]; Sphingolipid Delta4-desaturase (DES) [PF08557.12, score=57.5]} {Human: ENSG00000168350, DEGS2, delta 4-desaturase, sphingolipid 2, [Score=319, Expect=2e-107]; ENSG00000143753, DEGS1, delta 4-desaturase, sphingolipid 1, [Score=315, Expect=4e-106]} {Mouse: ENSMUSG00000038633, Degs1, delta(4)-desaturase, sphingolipid 1, [Score=309, Expect=7e-104]; ENSMUSG00000021263, Degs2, delta(4)-desaturase, sphingolipid 2, [Score=307, Expect=5e-103]} {Dmel: FBgn0001941, ifc, infertile crescent, [Score=345, Expect=4e-118]} {Celegans: WBGene00017996, F33D4.4, Putative sphingolipid delta(4)-desaturase, [Score=318, Expect=3e-107]} {Smed: dd_Smed_v6_7414_0_1, dd_Smed_v6_7414_0_1, [RH, Score=409, Expect=4e-143]} {RNA1310_20672.1} {RNA815_19986}
67. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

2.835 0.928 - 0.940 - - 0.967

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
68. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

GUCY2F 2.835 0.942 - 0.933 - - 0.960

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
69. MligTC455_32025 18 0.36 Mlig455_028181, Mlig455_028252

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.602

2.829 0.982 - 0.989 - 0.858 -

Mlig455_028181 {REF} {Length: 4403} {Pfam: PH domain [PF00169.31, score=19.7]} {RNA1310_106355}

Mlig455_028252 {REF} {Length: 3659} {Pfam: PH domain [PF00169.31, score=20.0]} {RNA1310_106355}
70. MligTC455_17363 62 1.28 Mlig455_003936

Neo: -

Age: -

2.829 0.991 - 0.881 - - 0.957 Mlig455_003936 {REF} {Length: 1252} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=45.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=26.4]} {RNA1310_47889} {RNA815_24646}
71. MligTC455_30839 19 0.39 Mlig455_027444

Neo: -

Age: -

2.827 0.916 - 0.976 - - 0.935 Mlig455_027444 {REF} {Length: 516} {NoTransDecoderORF} {RNA1310_123335}
72. MligTC455_15344 63 1.3 Mlig455_037163, Mlig455_052315

Neo: -

Age: -

FEV 2.825 0.954 - 0.941 - - 0.930

Mlig455_037163 {REF} {Length: 2044} {Pfam: Ets-domain [PF00178.24, score=118.9]} {Human: ENSG00000163497, FEV, FEV, ETS transcription factor, [RH, Score=186, Expect=7e-58]} {Mouse: ENSMUSG00000055197, Fev, FEV (ETS oncogene family), [RH, Score=187, Expect=4e-58]} {Dmel: FBgn0005658, Ets65A, Ets at 65A, [Score=206, Expect=2e-65]} {Celegans: WBGene00020368, ast-1, Axon STeering defect, [RH, Score=196, Expect=2e-60]} {Smed: dd_Smed_v6_11113_0_1, dd_Smed_v6_11113_0_1, [Score=226, Expect=3e-72]} {RNA1509_29423} {RNA1310_30786.1} {RNA815_45406}

Mlig455_052315 {REF} {Length: 2061} {Pfam: Ets-domain [PF00178.24, score=118.7]; Protein of unknown function (DUF2722) [PF10846.10, score=18.2]} {Human: ENSG00000163497, FEV, FEV, ETS transcription factor, [RH, Score=186, Expect=2e-57]} {Mouse: ENSMUSG00000055197, Fev, FEV (ETS oncogene family), [RH, Score=186, Expect=1e-57]} {Dmel: FBgn0005658, Ets65A, Ets at 65A, [Score=207, Expect=2e-65]} {Celegans: WBGene00020368, ast-1, Axon STeering defect, [RH, Score=196, Expect=4e-60]} {Smed: dd_Smed_v6_14611_0_1, dd_Smed_v6_14611_0_1, [RH, Score=211, Expect=7e-65]} {RNA1509_29423} {RNA1310_30786.1} {RNA815_45406}
73. MligTC455_12183 53 1.11 Mlig455_004166, Mlig455_004190

Neo: -

Age: -

Region-enriched R2: 4.930/0.01881

2.818 0.983 - 0.947 - - 0.888

Mlig455_004166 {REF} {Length: 2818} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=57.4]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=29.1]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=55.5, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=8e-12]} {RNA1310_64973} {RNA815_58453}

Mlig455_004190 {REF} {Length: 2742} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.7]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=28.6]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=56.2, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=1e-11]} {RNA1310_62602} {RNA815_58453}
74. MligTC455_39544 611 12.73 Mlig455_001809, Mlig455_001836, Mlig455_062227, Mlig455_062236

Neo: -

Age: -

Region-specific R2: 8.576

Region-enriched R2: 8.112/0.00016

2.818 0.956 - 0.944 - - 0.918

Mlig455_001809 {REF} {Length: 1067} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_001836 {REF} {Length: 1065} {RNA1509_52939} {RNA1310_72581, RNA1509_52939} {RNA1509_52939, RNA815_24546}

Mlig455_062227 {REF} {Length: 3520} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_062236 {REF} {Length: 620} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}
75. MligTC455_19775 36 0.74 Mlig455_060359

Neo: -

Age: -

FCN1 2.815 0.991 - 0.930 - - 0.894 Mlig455_060359 {REF} {Length: 1109} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=99.0, Expect=2e-23]; ENSG00000142748, FCN3, ficolin 3, [Score=99.0, Expect=1e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=2e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=3e-24]} {Dmel: FBgn0034160, CG5550, [Score=97.8, Expect=7e-24]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=90.1, Expect=4e-20]} {RNA1310_67383} {RNA815_45536}
76. MligTC455_49919 745 15.52 Mlig455_017182, Mlig455_048150

Neo: -

Age: -

Region-specific R2: 7.180

Region-enriched R2: 7.978/0.00000

Regeneration-downregulated R2: -4.649

Regeneration-depleted R2: -4.649

2.814 0.908 - 0.951 - - 0.955

Mlig455_017182 {REF} {Length: 576} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1310_60849, RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1509_35830, RNA1509_49816, RNA1509_53987, RNA815_31347}

Mlig455_048150 {REF} {Length: 574} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830} {RNA1310_60849} {RNA815_31347}
77. MligTC455_45712 91 1.89 Mlig455_050761, Mlig455_050791

Neo: -

Age: -

2.812 0.935 - 0.968 - - 0.909

Mlig455_050761 {REF} {Length: 2816} {RNA1509_10628} {RNA1310_39724.1} {RNA815_34935}

Mlig455_050791 {REF} {Length: 2817} {RNA1509_10628} {RNA1310_39724.1} {RNA815_34935}
78. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

ANGPTL1 2.809 0.939 - 0.919 - - 0.951 Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
79. MligTC455_13101 40 0.83 Mlig455_041354

Neo: -

Age: Up-Down-Down

NWD2 2.805 - - 0.987 - 0.863 0.955 Mlig455_041354 {REF} {Length: 5076} {Pfam: AAA ATPase domain [PF13191.8, score=35.4]; NACHT domain [PF05729.14, score=28.8]; WD domain, G-beta repeat [PF00400.34, score=23.9]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=353, Expect=5e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=338, Expect=3e-94]} {Dmel: FBgn0038397, CG10185, [RH, Score=1016, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [Score=738, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=212, Expect=4e-55]} {RNA1509_20730} {RNA1310_1147} {RNA815_11922}
80. MligTC455_35583 48 0.99 Mlig455_009953

Neo: -

Age: -

2.8 - - 0.989 - 0.851 0.960 Mlig455_009953 {REF} {Length: 919} {Pfam: Lectin C-type domain [PF00059.23, score=25.9]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=61.6, Expect=2e-11]} {RNA1509_20946} {RNA1310_71370} {RNA815_4785.4}
81. MligTC455_18506 59 1.23 Mlig455_038054

Neo: -

Age: Down-Up-Down

SP9 2.797 - - 0.979 - 0.866 0.952 Mlig455_038054 {REF} {Length: 3168} {Pfam: Zinc-finger double domain [PF13465.8, score=49.0]; Zinc finger, C2H2 type [PF00096.28, score=40.9]; C2H2-type zinc finger [PF13894.8, score=26.8]} {Human: ENSG00000217236, SP9, Sp9 transcription factor, [RH, Score=202, Expect=4e-59]; ENSG00000164651, SP8, Sp8 transcription factor, [RH, Score=202, Expect=5e-59]} {Mouse: ENSMUSG00000068859, Sp9, trans-acting transcription factor 9, [RH, Score=202, Expect=3e-59]; ENSMUSG00000048562, Sp8, trans-acting transcription factor 8, [RH, Score=201, Expect=9e-59]} {Dmel: FBgn0020378, Sp1, [RH, Score=198, Expect=6e-56]} {Celegans: WBGene00012735, sptf-3, SP (Specificity Protein) Transcription Factor, [Score=137, Expect=1e-35]} {Smed: dd_Smed_v6_17385_0_1, dd_Smed_v6_17385_0_1, [RH, Score=160, Expect=5e-46]} {RNA1310_42373}
82. MligTC455_17218 37 0.78 Mlig455_053853

Neo: -

Age: -

2.793 0.943 - 0.893 - - 0.957 Mlig455_053853 {REF} {Length: 1743} {RNA1310_61921}
83. MligTC455_48634 30 0.62 Mlig455_006052, Mlig455_068060

Neo: -

Age: -

ANGPTL4, FCN2 2.792 - - 0.997 - 0.838 0.957

Mlig455_006052 {REF} {Length: 2091} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=64.0]} {Human: ENSG00000160339, FCN2, ficolin 2, [Score=83.6, Expect=2e-17]} {Mouse: ENSMUSG00000042436, Mfap4, microfibrillar-associated protein 4, [Score=71.6, Expect=9e-14]} {Dmel: FBgn0034160, CG5550, [Score=67.4, Expect=2e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=62.0, Expect=2e-10]} {RNA1310_118683}

Mlig455_068060 {REF} {Length: 1573} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.6]} {Human: ENSG00000167772, ANGPTL4, angiopoietin like 4, [Score=53.9, Expect=9e-08]} {Mouse: ENSMUSG00000028553, Angptl3, angiopoietin-like 3, [Score=50.4, Expect=9e-07]} {Dmel: FBgn0050280, CG30280, [Score=57.0, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=53.9, Expect=3e-08]} {RNA1310_87835}
84. MligTC455_52629 472 9.83 Mlig455_059435

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.775

Region-enriched R2: 6.727/0.00002

2.791 0.855 - 0.979 - - 0.957 Mlig455_059435 {REF} {Length: 726} {RNA1509_48505} {RNA1310_62885} {RNA815_39881}
85. MligTC455_11229 51 1.06 Mlig455_054212

Neo: -

Age: -

2.79 - - 0.956 - 0.879 0.955 Mlig455_054212 {REF} {Length: 1481} {RNA1310_23944} {RNA815_32018}
86. MligTC455_50344 24 0.51 Mlig455_054355

Neo: -

Age: -

2.79 0.991 - - - 0.842 0.957 Mlig455_054355 {REF} {Length: 1376} {RNA1310_56750}
87. MligTC455_45032 56 1.16 Mlig455_034186

Neo: -

Age: -

KREMEN1 2.786 - - 0.999 - 0.830 0.957 Mlig455_034186 {REF} {Length: 1010} {Pfam: WSC domain [PF01822.21, score=53.3]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=51.2, Expect=3e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=53.9, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=47.8, Expect=3e-06]} {RNA1310_39474.1} {RNA815_33128}
88. MligTC455_44525 3358 69.96 Mlig455_004678, Mlig455_004741, Mlig455_004755, Mlig455_004840

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.742

Region-enriched R2: 10.296/0.00000
Region-enriched R3: 3.568/0.01807

2.783 0.870 - 0.959 - - 0.954

Mlig455_004678 {REF} {Length: 845} {RNA1509_25712} {RNA1310_68954.2} {RNA815_35323}

Mlig455_004741 {REF} {Length: 961} {RNA1509_25712} {RNA1310_68954.1} {RNA815_35323}

Mlig455_004755 {REF} {Length: 1059} {RNA1509_25712} {RNA1310_68954.2} {RNA815_35323}

Mlig455_004840 {REF} {Length: 918} {RNA1509_25712, RNA1509_29691} {RNA1310_68954.2, RNA1509_25712, RNA1509_29691} {RNA1509_25712, RNA1509_29691, RNA815_35323}
89. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

2.778 - - 0.982 - 0.850 0.946

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
90. MligTC455_14059 24 0.5 Mlig455_037086

Neo: -

Age: -

Region-enriched R2: 8.935/0.00338

2.777 0.991 - - - 0.829 0.957 Mlig455_037086 {REF} {Length: 1622} {Pfam: Galactosyltransferase [PF01762.23, score=18.6]} {RNA1310_57689} {RNA815_57743}
91. MligTC455_52120 179 3.73 Mlig455_024423, Mlig455_024577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.068/0.01755

POU4F3 2.776 0.902 - 0.960 - - 0.914

Mlig455_024423 {REF} {Length: 1288} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}

Mlig455_024577 {REF} {Length: 1325} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}
92. MligTC455_45039 168 3.49 Mlig455_040482, Mlig455_040487

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.332/0.02336

2.775 - - 0.968 - 0.849 0.958

Mlig455_040482 {REF} {Length: 1774} {RNA1310_20941} {RNA815_45079}

Mlig455_040487 {REF} {Length: 5763} {tRNA: Val(CAC),pseudo, score=20.2} {Celegans: WBGene00022195, Y71H2B.5, [Score=146, Expect=8e-36]} {Smed: dd_Smed_v6_16438_0_2, dd_Smed_v6_16438_0_2, [Score=188, Expect=1e-49]} {RNA1509_21228} {RNA1310_20941} {RNA815_45079}
93. MligTC455_49958 16 0.32 Mlig455_014437, Mlig455_070189

Neo: -

Age: -

2.774 - - 0.976 - 0.835 0.963

Mlig455_014437 {REF} {Length: 921} {RNA1310_45206} {RNA815_28788}

Mlig455_070189 {REF} {Length: 739} {RNA1310_45206} {RNA815_28788}
94. MligTC455_50694 602 12.54 Mlig455_058794, Mlig455_070066

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.478

Region-enriched R2: 3.805/0.01454

2.774 0.929 - 0.891 - - 0.954

Mlig455_058794 {REF} {Length: 776} {RNA1310_76208} {RNA815_49041}

Mlig455_070066 {REF} {Length: 781} {RNA1310_76208} {RNA815_49041}
95. MligTC455_35773 89 1.86 Mlig455_064449, Mlig455_064456

Neo: -

Age: -

Region-enriched R2: 5.198/0.00725

NANP 2.773 0.926 - 0.993 - - 0.854

Mlig455_064449 {REF} {Length: 503} {NoTransDecoderORF} {RNA1310_53432.2}

Mlig455_064456 {REF} {Length: 3122} {Pfam: Haloacid dehalogenase-like hydrolase [PF13419.8, score=56.3]; haloacid dehalogenase-like hydrolase [PF00702.28, score=55.3]; HAD-hyrolase-like [PF13242.8, score=44.6]} {Human: ENSG00000170191, NANP, N-acetylneuraminic acid phosphatase, [RH, Score=47.4, Expect=8e-06]} {Mouse: ENSMUSG00000053916, Nanp, N-acetylneuraminic acid phosphatase, [RH, Score=48.5, Expect=2e-06]} {Celegans: WBGene00018465, F45E1.4, [RH, Score=147, Expect=4e-43]} {Smed: dd_Smed_v6_2813_0_3, dd_Smed_v6_2813_0_3, [Score=174, Expect=2e-50]} {RNA1310_59243} {RNA815_62364}
96. MligTC455_50546 21 0.44 Mlig455_045408

Neo: -

Age: -

2.772 - - 0.990 - 0.829 0.953 Mlig455_045408 {REF} {Length: 1345} {RNA1310_102440}
97. MligTC455_39179 44 0.91 Mlig455_052012

Neo: -

Age: Down-Up-Up

TCTE3 2.769 0.991 - - - 0.821 0.957 Mlig455_052012 {REF} {Length: 1042} {Pfam: Tctex-1 family [PF03645.15, score=42.5]} {Human: ENSG00000184786, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]; ENSG00000275368, TCTE3, t-complex-associated-testis-expressed 3, [RH, Score=65.9, Expect=8e-13]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=61.6, Expect=1e-11]} {Smed: dd_Smed_v6_9036_0_1, dd_Smed_v6_9036_0_1, [Score=92.8, Expect=1e-23]} {RNA1509_34873} {RNA1310_34743} {RNA815_18661}
98. MligTC455_41540 190 3.96 Mlig455_060056

Neo: -

Age: -

Region-enriched R2: 6.605/0.00196

GLUL 2.767 - - 0.972 - 0.838 0.957 Mlig455_060056 {REF} {Length: 1355} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.3]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=47.5]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=511, Expect=1e-180]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=511, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=515, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=545, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.2} {RNA815_4116.6}
99. MligTC455_15450 19 0.39 Mlig455_006618

Neo: -

Age: -

2.76 - - 0.955 - 0.848 0.957 Mlig455_006618 {REF} {Length: 653} {Pfam: WSC domain [PF01822.21, score=30.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.5, Expect=7e-09]} {RNA1310_35396.1} {RNA815_56551}
100. MligTC455_18748 104 2.17 Mlig455_024985, Mlig455_024999

Neo: -

Age: -

Region-enriched R2: 6.002/0.00016
Region-enriched R4: 3.433/0.02745

GRIK4 2.754 0.948 - 0.842 - - 0.964

Mlig455_024985 {REF} {Length: 1514} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_47299} {RNA815_38321}

Mlig455_024999 {REF} {Length: 3567} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_7578, RNA1509_35538} {RNA1509_35538, RNA815_4987}

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