Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_16029 | 143 | 2.99 | Mlig455_015088 | Neo: - Age: - |
CDK11B | Mlig455_015088 {REF} {Length: 6058} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=215.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=97.1]; BTB/POZ domain [PF00651.33, score=82.9]; Kinase-like [PF14531.8, score=22.5]; Peptidase family S64 [PF08192.13, score=17.6]} {Human: ENSG00000248333, CDK11B, cyclin dependent kinase 11B, [RH, Score=514, Expect=4e-165]; ENSG00000008128, CDK11A, cyclin dependent kinase 11A, [RH, Score=508, Expect=1e-162]} {Mouse: ENSMUSG00000029062, Cdk11b, cyclin-dependent kinase 11B, [RH, Score=512, Expect=2e-164]} {Dmel: FBgn0016696, Pitslre, [RH, Score=502, Expect=1e-158]} {Celegans: WBGene00015203, cdk-11.1, Putative serine/threonine-protein kinase B0495.2, [RH, Score=432, Expect=2e-135]} {Smed: dd_Smed_v6_3540_0_3, dd_Smed_v6_3540_0_3, [RH, Score=495, Expect=4e-159]} {RNA1509_23995} {RNA1310_10655} {RNA815_5865} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.84 | 2.36 | 0.72409 | 1.00000 | |
RegionR2 | 0.106 | 2.36 | 0.89545 | 1.00000 | |
RegionR3 | 0.102 | 2.36 | 0.87380 | 1.00000 | |
RegionR4 | 0.113 | 2.36 | 0.87559 | 1.00000 | |
RegionR5 | 0.894 | 2.36 | 0.09205 | 0.28852 | |
RegionR6 | 0.328 | 2.36 | 0.62329 | 1.00000 | |
RegionR7 | -0.262 | 2.36 | 0.80956 | 1.00000 | |
RegionR8 | -0.441 | 2.36 | 0.75841 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -4.263 | 2.36 | 0.52101 | 1.00000 | |
RegenerationR2 | -1.417 | 2.36 | 0.04423 | 0.34754 | |
RegenerationR3 | -0.712 | 2.36 | 0.29977 | 0.73129 | |
RegenerationR4 | -0.363 | 2.36 | 0.58271 | 0.90623 | |
RegenerationR5 | -0.601 | 2.36 | 0.26541 | 0.69698 | |
RegenerationR6 | 0.226 | 2.36 | 0.72369 | 0.93781 | |
RegenerationBL | 1.065 | 2.36 | 0.22719 | 0.57712 | |
RegenerationTP | 0.826 | 2.36 | 0.43980 | 0.85990 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_16029 | 143 | 2.99 | Mlig455_015088 | Neo: - Age: - |
CDK11B | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_015088 {REF} {Length: 6058} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=215.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=97.1]; BTB/POZ domain [PF00651.33, score=82.9]; Kinase-like [PF14531.8, score=22.5]; Peptidase family S64 [PF08192.13, score=17.6]} {Human: ENSG00000248333, CDK11B, cyclin dependent kinase 11B, [RH, Score=514, Expect=4e-165]; ENSG00000008128, CDK11A, cyclin dependent kinase 11A, [RH, Score=508, Expect=1e-162]} {Mouse: ENSMUSG00000029062, Cdk11b, cyclin-dependent kinase 11B, [RH, Score=512, Expect=2e-164]} {Dmel: FBgn0016696, Pitslre, [RH, Score=502, Expect=1e-158]} {Celegans: WBGene00015203, cdk-11.1, Putative serine/threonine-protein kinase B0495.2, [RH, Score=432, Expect=2e-135]} {Smed: dd_Smed_v6_3540_0_3, dd_Smed_v6_3540_0_3, [RH, Score=495, Expect=4e-159]} {RNA1509_23995} {RNA1310_10655} {RNA815_5865} |
2. | MligTC455_17501 | 114 | 2.37 | Mlig455_002481 | Neo: - Age: - |
1.816 | - | - | 0.960 | 0.856 | - | - | Mlig455_002481 {REF} {Length: 2949} {RNA1509_41440} {RNA1310_26404.1, RNA1509_41440} {RNA1509_41440, RNA815_11074.1} | |
3. | MligTC455_31938 | 131 | 2.74 | Mlig455_041047 | Neo: - Age: - |
1.742 | - | - | - | - | 0.775 | 0.967 | Mlig455_041047 {REF} {Length: 1376} {RNA1509_52877} {RNA1310_44065.2} {RNA815_31243} | |
4. | MligTC455_22433 | 447 | 9.31 | Mlig455_026751, Mlig455_051741 | Neo: Int S/G2/M Age: Up-Down-Down |
USP49 | 0.977 | - | - | - | - | - | 0.977 | Mlig455_026751 {REF} {Length: 7322} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=118.0]} {Human: ENSG00000164663, USP49, ubiquitin specific peptidase 49, [Score=52.0, Expect=4e-06]; ENSG00000140455, USP3, ubiquitin specific peptidase 3, [Score=52.0, Expect=3e-06]} {Mouse: ENSMUSG00000053483, Usp21, ubiquitin specific peptidase 21, [Score=50.1, Expect=9e-06]; ENSMUSG00000090115, Usp49, ubiquitin specific peptidase 49, [Score=49.7, Expect=1e-05]; ENSMUSG00000032376, Usp3, ubiquitin specific peptidase 3, [Score=49.3, Expect=1e-05]} {RNA1509_14174} {RNA1310_11133, RNA1509_14174} {RNA1509_14174, RNA815_3873.1} Mlig455_051741 {REF} {Length: 7065} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=118.3]} {Human: ENSG00000164663, USP49, ubiquitin specific peptidase 49, [Score=52.8, Expect=2e-06]; ENSG00000140455, USP3, ubiquitin specific peptidase 3, [Score=52.0, Expect=2e-06]} {Mouse: ENSMUSG00000053483, Usp21, ubiquitin specific peptidase 21, [Score=50.4, Expect=6e-06]; ENSMUSG00000090115, Usp49, ubiquitin specific peptidase 49, [Score=49.7, Expect=1e-05]; ENSMUSG00000032376, Usp3, ubiquitin specific peptidase 3, [Score=49.3, Expect=1e-05]} {RNA1509_14174, RNA1509_41159} {RNA1310_11133, RNA1509_41159} {RNA1509_41159, RNA815_3873.1} |
5. | MligTC455_22354 | 65 | 1.35 | Mlig455_009895, Mlig455_057001, Mlig455_057061 | Neo: - Age: logFC(26M/2M)=0.575 |
EIF2B3, PPM1A | 0.966 | - | - | - | 0.966 | - | - | Mlig455_009895 {REF} {Length: 1696} {TRANSSPLICED} {Pfam: MobA-like NTP transferase domain [PF12804.9, score=34.3]; Nucleotidyl transferase [PF00483.25, score=31.3]; Domain of unknown function (DUF4954) [PF16314.7, score=23.8]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=20.2]} {Human: ENSG00000070785, EIF2B3, eukaryotic translation initiation factor 2B subunit gamma, [Score=111, Expect=5e-26]} {Mouse: ENSMUSG00000028683, Eif2b3, eukaryotic translation initiation factor 2B, subunit 3, [Score=124, Expect=1e-30]} {Dmel: FBgn0034029, eIF2Bgamma, eukaryotic translation initiation factor 2B subunit gamma, [RH, Score=139, Expect=4e-36]} {Celegans: WBGene00004090, eif-2Bgamma, Probable translation initiation factor eIF-2B subunit gamma, [RH, Score=72.0, Expect=2e-13]} {RNA1509_11665} {RNA1310_17674} {RNA815_11116} Mlig455_057001 {REF} {Length: 983} {Pfam: Domain of unknown function (DUF4954) [PF16314.7, score=25.6]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=23.3]} {Dmel: FBgn0034029, eIF2Bgamma, eukaryotic translation initiation factor 2B subunit gamma, [Score=73.6, Expect=2e-14]} {Celegans: WBGene00004090, eif-2Bgamma, Probable translation initiation factor eIF-2B subunit gamma, [RH, Score=71.2, Expect=8e-14]} {RNA1509_11665} {RNA1310_17674} {RNA815_11116} Mlig455_057061 {REF} {Length: 1331} {Pfam: Domain of unknown function (DUF4954) [PF16314.7, score=24.3]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=21.9]} {Human: ENSG00000100614, PPM1A, protein phosphatase, Mg2+/Mn2+ dependent 1A, [Score=50.1, Expect=4e-07]; ENSG00000138032, PPM1B, protein phosphatase, Mg2+/Mn2+ dependent 1B, [Score=48.9, Expect=1e-05]; ENSG00000285542, AC013717.1, novel protein, PPM1B-SLC3A1 readthrough, [Score=48.5, Expect=1e-05]} {Mouse: ENSMUSG00000021096, Ppm1a, protein phosphatase 1A, magnesium dependent, alpha isoform, [Score=52.0, Expect=7e-07]; ENSMUSG00000061130, Ppm1b, protein phosphatase 1B, magnesium dependent, beta isoform, [Score=49.7, Expect=4e-06]} {Dmel: FBgn0034029, eIF2Bgamma, eukaryotic translation initiation factor 2B subunit gamma, [Score=75.1, Expect=2e-14]} {Celegans: WBGene00004090, eif-2Bgamma, Probable translation initiation factor eIF-2B subunit gamma, [RH, Score=71.2, Expect=2e-13]} {Smed: dd_Smed_v6_2275_0_1, dd_Smed_v6_2275_0_1, [Score=61.6, Expect=2e-10]} {RNA1509_11665} {RNA1310_17674} {RNA815_11116} |
6. | MligTC455_47349 | 1450 | 30.22 | Mlig455_010530, Mlig455_061804 | Neo: Neoblast, stringent Age: - Region-enriched R5: 1.675/0.00004 |
DNMT3B | 0.964 | - | - | - | - | - | 0.964 | Mlig455_010530 {REF} {Length: 2248} {TRANSSPLICED} {Pfam: Cysteine rich ADD domain in DNMT3 [PF17980.3, score=29.7]} {Human: ENSG00000088305, DNMT3B, DNA methyltransferase 3 beta, [Score=89.0, Expect=1e-17]} {Mouse: ENSMUSG00000027478, Dnmt3b, DNA methyltransferase 3B, [Score=97.1, Expect=2e-20]; ENSMUSG00000082079, Dnmt3c, DNA methyltransferase 3C, [Score=94.7, Expect=1e-19]} {RNA1509_23149} {RNA1310_10697.1, RNA1509_23149} {RNA1509_23149, RNA815_14886} Mlig455_061804 {REF} {Length: 2249} {TRANSSPLICED} {Pfam: Cysteine rich ADD domain in DNMT3 [PF17980.3, score=29.7]} {Human: ENSG00000088305, DNMT3B, DNA methyltransferase 3 beta, [Score=89.4, Expect=9e-18]} {Mouse: ENSMUSG00000027478, Dnmt3b, DNA methyltransferase 3B, [Score=97.1, Expect=2e-20]; ENSMUSG00000082079, Dnmt3c, DNA methyltransferase 3C, [Score=94.7, Expect=9e-20]} {RNA1509_23149} {RNA1310_10697.1} {RNA815_14886} |
7. | MligTC455_50916 | 879 | 18.31 | Mlig455_028663, Mlig455_028694 | Neo: Irradiation Age: - |
0.959 | - | - | - | - | - | 0.959 | Mlig455_028663 {REF} {Length: 2888} {Pfam: Microtubule associated protein (MAP65/ASE1 family) [PF03999.14, score=97.7]} {Smed: dd_Smed_v6_12013_0_1, dd_Smed_v6_12013_0_1, [Score=64.7, Expect=7e-11]} {RNA1509_8219} {RNA1310_6966.1} {RNA815_1972.1} Mlig455_028694 {REF} {Length: 2675} {Pfam: Microtubule associated protein (MAP65/ASE1 family) [PF03999.14, score=95.3]} {Smed: dd_Smed_v6_12013_0_1, dd_Smed_v6_12013_0_1, [Score=66.2, Expect=2e-11]} {RNA1509_8219} {RNA1310_1428.1, RNA1509_8219} {RNA1509_8219, RNA815_1972.1} |
|
8. | MligTC455_48983 | 364 | 7.59 | Mlig455_006479 | Neo: - Age: - |
HEXB | 0.953 | - | - | - | - | - | 0.953 | Mlig455_006479 {REF} {Length: 4395} {TRANSSPLICED} {Pfam: Glycosyl hydrolase family 20, catalytic domain [PF00728.24, score=279.9]; beta-acetyl hexosaminidase like [PF14845.8, score=64.9]; Glycosyl hydrolase family 20, domain 2 [PF02838.17, score=25.4]} {Human: ENSG00000049860, HEXB, hexosaminidase subunit beta, [Score=404, Expect=3e-131]; ENSG00000213614, HEXA, hexosaminidase subunit alpha, [Score=392, Expect=6e-127]} {Mouse: ENSMUSG00000021665, Hexb, hexosaminidase B, [Score=397, Expect=5e-129]; ENSMUSG00000025232, Hexa, hexosaminidase A, [Score=393, Expect=1e-127]} {Dmel: FBgn0045063, fdl, fused lobes, [RH, Score=214, Expect=4e-59]} {Celegans: WBGene00020509, hex-1, Beta-hexosaminidase A, [Score=313, Expect=1e-96]} {Smed: dd_Smed_v6_3964_0_1, dd_Smed_v6_3964_0_1, [RH, Score=477, Expect=1e-156]} {RNA1509_11107} {RNA1310_1997.1} {RNA815_5636} |
9. | MligTC455_38386 | 276 | 5.74 | Mlig455_019773 | Neo: Int S/G2/M Age: - Region-enriched R4: 1.680/0.04858 |
PSMC3 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_019773 {REF} {Length: 2330} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=141.5]; Proteasomal ATPase OB C-terminal domain [PF16450.7, score=53.2]; AAA+ lid domain [PF17862.3, score=46.2]; AAA ATPase domain [PF13191.8, score=27.8]; AAA domain (dynein-related subfamily) [PF07728.16, score=26.8]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=23.4]; AAA domain (Cdc48 subfamily) [PF07724.16, score=21.6]; AAA domain [PF13401.8, score=20.5]; Protein of unknown function (DUF815) [PF05673.15, score=18.1]} {Human: ENSG00000165916, PSMC3, proteasome 26S subunit, ATPase 3, [RH, Score=726, Expect=0.0]} {Mouse: ENSMUSG00000002102, Psmc3, proteasome (prosome, macropain) 26S subunit, ATPase 3, [RH, Score=727, Expect=0.0]} {Dmel: FBgn0028684, Rpt5, Regulatory particle triple-A ATPase 5, [RH, Score=726, Expect=0.0]} {Celegans: WBGene00004505, rpt-5, Proteasome Regulatory Particle, ATPase-like, [RH, Score=711, Expect=0.0]} {Smed: dd_Smed_v6_1855_0_1, dd_Smed_v6_1855_0_1, [RH, Score=741, Expect=0.0]} {RNA1509_11369} {RNA1310_10892, RNA1509_11369} {RNA1509_11369, RNA815_3190} |
10. | MligTC455_41238 | 268 | 5.58 | Mlig455_014819 | Neo: - Age: - |
NDOR1 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_014819 {REF} {Length: 5603} {Pfam: Flavodoxin [PF00258.27, score=66.4]; FAD binding domain [PF00667.22, score=60.7]; Oxidoreductase NAD-binding domain [PF00175.23, score=43.6]} {Human: ENSG00000188566, NDOR1, NADPH dependent diflavin oxidoreductase 1, [RH, Score=361, Expect=3e-115]} {Mouse: ENSMUSG00000006471, Ndor1, NADPH dependent diflavin oxidoreductase 1, [RH, Score=363, Expect=2e-116]} {Dmel: FBgn0035890, CG13667, [RH, Score=295, Expect=1e-90]} {Celegans: WBGene00001485, fre-1, NADPH-dependent diflavin oxidoreductase 1, [RH, Score=300, Expect=7e-93]} {Smed: dd_Smed_v6_17265_0_1, dd_Smed_v6_17265_0_1, [RH, Score=339, Expect=1e-107]} {RNA1509_17019, RNA1509_19226} {RNA1310_9966, RNA1509_17019} {RNA1509_17019, RNA815_3436} |