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Results for MligTC455_16507

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_16507 120 2.50 Mlig455_062916

Neo: -

Age: -

 CTNS Mlig455_062916 {REF} {Length: 2187} {Pfam: PQ loop repeat [PF04193.16, score=98.2]} {Human: ENSG00000040531, CTNS, cystinosin, lysosomal cystine transporter, [Score=252, Expect=4e-79]} {Mouse: ENSMUSG00000005949, Ctns, cystinosis, nephropathic, [Score=246, Expect=2e-77]} {Dmel: FBgn0039045, CG17119, [RH, Score=269, Expect=4e-86]} {Celegans: WBGene00008052, ctns-1, Cystinosin homolog, [RH, Score=228, Expect=2e-70]} {Smed: dd_Smed_v6_4571_0_1, dd_Smed_v6_4571_0_1, [RH, Score=271, Expect=8e-88]} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1310_18560, RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307, RNA815_7181}

Cumulative graph for MligTC455_16507

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.373 2.247 0.99957 1.00000
RegionR2 1.148 2.247 0.34949 0.74300
RegionR3 2.211 2.247 0.02440 0.26660
RegionR4 1.249 2.247 0.25563 0.55637
RegionR5 2.053 2.247 0.02824 0.12420
RegionR6 2.393 2.247 0.01822 0.24111
RegionR7 -4.377 2.247 0.99959 1.00000
RegionR8 0.695 2.247 0.57158 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.07 2.247 0.99994 1.00000
RegenerationR2 0.521 2.247 0.53588 0.88669
RegenerationR3 0.472 2.247 0.54943 0.88333
RegenerationR4 1.292 2.247 0.11941 0.52623
RegenerationR5 -0.039 2.247 0.95965 1.00000
RegenerationR6 0.467 2.247 0.55450 0.84188
RegenerationBL 0.599 2.247 0.61973 0.96254
RegenerationTP 4.157 2.247 0.00905 0.16067


Genes with expression patterns similar to MligTC455_16507

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_16507 120 2.5 Mlig455_062916

Neo: -

Age: -

 CTNS 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_062916 {REF} {Length: 2187} {Pfam: PQ loop repeat [PF04193.16, score=98.2]} {Human: ENSG00000040531, CTNS, cystinosin, lysosomal cystine transporter, [Score=252, Expect=4e-79]} {Mouse: ENSMUSG00000005949, Ctns, cystinosis, nephropathic, [Score=246, Expect=2e-77]} {Dmel: FBgn0039045, CG17119, [RH, Score=269, Expect=4e-86]} {Celegans: WBGene00008052, ctns-1, Cystinosin homolog, [RH, Score=228, Expect=2e-70]} {Smed: dd_Smed_v6_4571_0_1, dd_Smed_v6_4571_0_1, [RH, Score=271, Expect=8e-88]} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1310_18560, RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307, RNA815_7181}
2. MligTC455_43156 30659 638.72 Mlig455_013212, Mlig455_013235, Mlig455_013307

Neo: -

Age: logFC(26M/2M)=-0.210

Region-enriched R6: 1.505/0.00540
Region-enriched R5: 1.426/0.00133
Region-enriched R4: 1.190/0.03651

 2.411 - 0.719 - 0.961 - 0.731

Mlig455_013212 {REF} {Length: 1340} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=78.1]; Methyltransferase domain [PF13649.8, score=73.6]; Methyltransferase domain [PF13489.8, score=61.5]; Methyltransferase domain [PF08242.14, score=51.0]; Methyltransferase domain [PF13847.8, score=50.3]; ubiE/COQ5 methyltransferase family [PF01209.20, score=50.2]; Mycolic acid cyclopropane synthetase [PF02353.22, score=42.9]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=23.1]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=22.1]; Methyltransferase small domain [PF05175.16, score=21.3]; Tellurite resistance protein TehB [PF03848.16, score=20.1]} {Dmel: FBgn0032922, CG9249, [Score=47.8, Expect=4e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=182, Expect=1e-54]} {RNA1509_20289, RNA1509_5276, RNA1509_6525} {RNA1310_20797, RNA1509_20289, RNA1509_5276} {RNA1509_20289, RNA1509_5276, RNA815_10580.1}

Mlig455_013235 {REF} {Length: 1347} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=77.6]; Methyltransferase domain [PF13649.8, score=73.4]; Methyltransferase domain [PF13489.8, score=59.4]; Methyltransferase domain [PF08242.14, score=50.7]; Methyltransferase domain [PF13847.8, score=50.0]; ubiE/COQ5 methyltransferase family [PF01209.20, score=49.1]; Mycolic acid cyclopropane synthetase [PF02353.22, score=41.7]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=21.8]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=21.4]; Methyltransferase small domain [PF05175.16, score=19.5]} {Dmel: FBgn0032922, CG9249, [Score=48.1, Expect=3e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=181, Expect=4e-54]} {RNA1509_2488, RNA1509_52745, RNA1509_6525} {RNA1310_20797, RNA1509_2488, RNA1509_52745, RNA1509_6525} {RNA1509_2488, RNA1509_52745, RNA1509_6525, RNA815_10580.1}

Mlig455_013307 {REF} {Length: 1338} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=78.1]; Methyltransferase domain [PF13649.8, score=73.6]; Methyltransferase domain [PF13489.8, score=61.5]; Methyltransferase domain [PF08242.14, score=51.0]; Methyltransferase domain [PF13847.8, score=50.3]; ubiE/COQ5 methyltransferase family [PF01209.20, score=50.2]; Mycolic acid cyclopropane synthetase [PF02353.22, score=42.9]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=23.1]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=22.1]; Methyltransferase small domain [PF05175.16, score=21.3]; Tellurite resistance protein TehB [PF03848.16, score=20.1]} {Dmel: FBgn0032922, CG9249, [Score=47.8, Expect=4e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=182, Expect=1e-54]} {RNA1509_6525} {RNA1310_20797} {RNA815_10580.1}
3. MligTC455_51743 473 9.85 Mlig455_066181

Neo: -

Age: logFC(26M/2M)=-0.536

 1.802 - - - - 0.849 0.953 Mlig455_066181 {REF} {Length: 2582} {RNA1509_24668} {RNA1310_11745, RNA1509_24668} {RNA1509_24668, RNA815_6094}
4. MligTC455_14821 305 6.35 Mlig455_018773

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.196/0.03323
Region-enriched R5: 1.788/0.02997

 PANK1 1.678 - - - 0.965 - 0.713 Mlig455_018773 {REF} {Length: 2765} {Pfam: Fumble [PF03630.16, score=101.1]} {Human: ENSG00000152782, PANK1, pantothenate kinase 1, [Score=55.5, Expect=6e-08]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=79.7, Expect=9e-16]} {Dmel: FBgn0011205, fbl, fumble, [Score=56.2, Expect=2e-08]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=73.2, Expect=5e-14]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=182, Expect=4e-54]} {RNA1509_12016} {RNA1310_16423} {RNA815_7574.1}
5. MligTC455_15783 5345 111.36 Mlig455_025807, Mlig455_025814

Neo: -

Age: -

Region-enriched R4: 1.633/0.00032
Region-enriched R5: 1.583/0.00001
Region-enriched R6: 1.083/0.03690

 GULP1 1.67 0.718 - - 0.952 - -

Mlig455_025807 {REF} {Length: 1817} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.3, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]; ENSMUSG00000024219, Anks1, ankyrin repeat and SAM domain containing 1, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0029092, ced-6, [RH, Score=69.7, Expect=1e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=49.3, Expect=3e-06]} {RNA1509_14211, RNA1509_2504} {RNA1310_16087, RNA1509_14211, RNA1509_2504} {RNA1509_14211, RNA1509_2504, RNA815_6763}

Mlig455_025814 {REF} {Length: 1818} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.7, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]} {Dmel: FBgn0029092, ced-6, [RH, Score=68.2, Expect=3e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=47.8, Expect=8e-06]} {RNA1509_2504, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1310_16087, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1509_44856, RNA1509_48464, RNA1509_9772, RNA815_6763}
6. MligTC455_19691 169 3.53 Mlig455_029093

Neo: -

Age: -

 SMARCAL1 1 - - 1.000 - - - Mlig455_029093 {REF} {Length: 4025} {TRANSSPLICED} {Pfam: SNF2-related domain [PF00176.25, score=109.3]; HepA-related protein (HARP) [PF07443.15, score=66.4]; Helicase conserved C-terminal domain [PF00271.33, score=45.1]; Type III restriction enzyme, res subunit [PF04851.17, score=24.6]} {Human: ENSG00000138375, SMARCAL1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1, [RH, Score=470, Expect=6e-153]} {Mouse: ENSMUSG00000039354, Smarcal1, SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, [RH, Score=489, Expect=4e-161]} {Dmel: FBgn0031655, Marcal1, [RH, Score=376, Expect=2e-119]} {Celegans: WBGene00015806, smrc-1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 homolog, [RH, Score=409, Expect=4e-133]} {Smed: dd_Smed_v6_10238_0_1, dd_Smed_v6_10238_0_1, [RH, Score=513, Expect=2e-173]} {RNA1509_13058} {RNA1310_6023} {RNA815_1885.1}
7. MligTC455_39351 815 16.99 Mlig455_068114

Neo: -

Age: -

 RAB8B 0.988 - - - 0.988 - - Mlig455_068114 {REF} {Length: 1704} {Pfam: Ras family [PF00071.24, score=174.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.7]; ADP-ribosylation factor family [PF00025.23, score=55.4]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=151, Expect=2e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [Score=145, Expect=6e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=3e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=3e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=151, Expect=1e-45]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=148, Expect=2e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=144, Expect=2e-42]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [Score=144, Expect=3e-42]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=6e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=6e-52]} {RNA1509_18167, RNA1509_19859} {RNA1310_37116, RNA1509_18167, RNA1509_19859} {RNA1509_18167, RNA1509_19859, RNA815_17007}
8. MligTC455_52026 1687 35.15 Mlig455_004669, Mlig455_004733, Mlig455_004832

Neo: -

Age: logFC(26M/2M)=0.290

Region-enriched R5: 1.467/0.04312

 0.987 - - - 0.987 - -

Mlig455_004669 {REF} {Length: 1728} {RNA1509_23759} {RNA1310_39844} {RNA815_18443.1}

Mlig455_004733 {REF} {Length: 2712} {RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1310_39844, RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1509_23759, RNA1509_38591, RNA1509_46380, RNA815_18443.1}

Mlig455_004832 {REF} {Length: 1806} {RNA1509_23759, RNA1509_55627} {RNA1310_39844, RNA1509_55627} {RNA1509_55627, RNA815_18443.1}
9. MligTC455_17284 28 0.58 Mlig455_021795

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.028

 0.981 - - - 0.981 - - Mlig455_021795 {REF} {Length: 3140} {RNA1509_16895} {RNA1310_22424.1} {RNA815_3739}
10. MligTC455_45275 384 8 Mlig455_037525

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.804

Region-enriched R4: 2.211/0.00561

 0.971 - - - 0.971 - - Mlig455_037525 {REF} {Length: 1617} {Pfam: HYD1 signature containing ADP-ribosyltransferase [PF15633.8, score=44.2]} {RNA1509_38410, RNA1509_7973} {RNA1310_28627, RNA1509_38410, RNA1509_7973} {RNA1509_38410, RNA1509_7973, RNA815_9390.1}
11. MligTC455_18597 2002 41.7 Mlig455_008723, Mlig455_063593

Neo: -

Age: -

Region-enriched R5: 1.210/0.02582

 AGPS 0.97 - - - 0.970 - -

Mlig455_008723 {REF} {Length: 3049} {TRANSSPLICED} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=183.8]; FAD binding domain [PF01565.25, score=116.9]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [RH, Score=770, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [RH, Score=771, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [RH, Score=669, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [RH, Score=702, Expect=0.0]} {RNA1509_6531} {RNA1310_6470.2, RNA1509_6531} {RNA1509_6531, RNA815_2634}

Mlig455_063593 {REF} {Length: 3191} {TRANSSPLICED} {Pfam: FAD binding domain [PF01565.25, score=116.1]; FAD linked oxidases, C-terminal domain [PF02913.21, score=111.2]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [Score=683, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [Score=685, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [Score=566, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [Score=583, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [Score=620, Expect=0.0]} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA1509_6531} {RNA1310_6470.2, RNA1509_28418, RNA1509_50386, RNA1509_53669} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA815_2634}
12. MligTC455_39350 538 11.21 Mlig455_023484

Neo: -

Age: Down-Up-Down

Region-enriched R4: 3.492/0.00082
Region-enriched R5: 2.753/0.00156

 RAB8B 0.97 - - - 0.970 - - Mlig455_023484 {REF} {Length: 1074} {Pfam: Ras family [PF00071.24, score=174.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.8]; ADP-ribosylation factor family [PF00025.23, score=55.3]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=152, Expect=1e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=2e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=2e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=152, Expect=6e-46]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=147, Expect=3e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=145, Expect=5e-43]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=5e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=5e-52]} {RNA1509_19859, RNA1509_27459} {RNA1310_37116, RNA1509_27459} {RNA1509_27459, RNA815_17007}
13. MligTC455_42649 1111 23.15 Mlig455_033920

Neo: -

Age: logFC(26M/2M)=0.288

 TPTE2 0.97 - - - 0.970 - - Mlig455_033920 {REF} {Length: 2398} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=66.0]; Ion transport protein [PF00520.33, score=35.9]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=28.9]; Protein-tyrosine phosphatase [PF00102.29, score=24.5]; Inositol hexakisphosphate [PF14566.8, score=22.0]} {Human: ENSG00000132958, TPTE2, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2, [RH, Score=373, Expect=6e-124]} {Mouse: ENSMUSG00000031481, Tpte, transmembrane phosphatase with tensin homology, [RH, Score=384, Expect=1e-126]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=171, Expect=9e-48]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=137, Expect=5e-34]} {Smed: dd_Smed_v6_4925_0_2, dd_Smed_v6_4925_0_2, [RH, Score=424, Expect=7e-145]} {RNA1509_26060, RNA1509_6952} {RNA1310_16625.1, RNA1509_26060, RNA1509_6952} {RNA1509_26060, RNA1509_6952, RNA815_5966}
14. MligTC455_34755 1776 36.99 Mlig455_050399

Neo: -

Age: -

 PFKM 0.967 - - - 0.967 - - Mlig455_050399 {REF} {Length: 3919} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=609.5]} {Human: ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=830, Expect=0.0]} {Mouse: ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=826, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=805, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [Score=834, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=810, Expect=0.0]} {Smed: dd_Smed_v6_3613_0_1, dd_Smed_v6_3613_0_1, [Score=864, Expect=0.0]} {RNA1509_45109, RNA1509_4935} {RNA1310_2251.3, RNA1509_45109} {RNA1509_45109, RNA815_2567}
15. MligTC455_43797 2681 55.85 Mlig455_051343

Neo: -

Age: logFC(26M/2M)=0.181

Region-enriched R5: 1.067/0.00046

 SHMT2 0.967 - - - 0.967 - - Mlig455_051343 {REF} {Length: 1803} {TRANSSPLICED} {Pfam: Serine hydroxymethyltransferase [PF00464.21, score=614.7]} {Human: ENSG00000182199, SHMT2, serine hydroxymethyltransferase 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000025403, Shmt2, serine hydroxymethyltransferase 2 (mitochondrial), [RH, Score=657, Expect=0.0]} {Dmel: FBgn0029823, Shmt, Serine hydroxymethyl transferase, [RH, Score=594, Expect=0.0]} {Celegans: WBGene00003214, mel-32, Serine hydroxymethyltransferase, [RH, Score=567, Expect=0.0]} {Smed: dd_Smed_v6_7793_0_1, dd_Smed_v6_7793_0_1, [RH, Score=638, Expect=0.0]} {RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642} {RNA1310_15013, RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642} {RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642, RNA815_5372}
16. MligTC455_35519 1708 35.59 Mlig455_014621

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.589

Region-enriched R4: 1.911/0.00012
Region-enriched R3: 1.380/0.00213
Region-enriched R5: 1.309/0.00075

 SLC44A2 0.965 - - - 0.965 - - Mlig455_014621 {REF} {Length: 3582} {Pfam: Plasma-membrane choline transporter [PF04515.14, score=313.8]} {Human: ENSG00000129353, SLC44A2, solute carrier family 44 member 2, [Score=436, Expect=1e-142]} {Mouse: ENSMUSG00000057193, Slc44a2, solute carrier family 44, member 2, [Score=451, Expect=7e-149]} {Dmel: FBgn0039637, Ctl2, Choline transporter-like 2, [Score=315, Expect=4e-96]} {Celegans: WBGene00018037, chtl-1, Choline transporter-like protein 1, [Score=373, Expect=1e-118]} {Smed: dd_Smed_v6_6488_0_1, dd_Smed_v6_6488_0_1, [Score=434, Expect=7e-142]} {RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1310_8213, RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1509_14161, RNA1509_56009, RNA1509_8961, RNA815_109}
17. MligTC455_41002 233 4.84 Mlig455_022813

Neo: -

Age: -

 PNPLA2 0.965 - - - 0.965 - - Mlig455_022813 {REF} {Length: 4359} {TRANSSPLICED} {Pfam: Patatin-like phospholipase [PF01734.24, score=37.5]} {Human: ENSG00000177666, PNPLA2, patatin like phospholipase domain containing 2, [RH, Score=206, Expect=8e-59]} {Mouse: ENSMUSG00000025509, Pnpla2, patatin-like phospholipase domain containing 2, [RH, Score=203, Expect=4e-58]} {Dmel: FBgn0036449, bmm, brummer, [RH, Score=247, Expect=5e-74]} {Celegans: WBGene00015484, atgl-1, Patanin-like phospholipase domain-containing protein, [RH, Score=188, Expect=3e-51]} {Smed: dd_Smed_v6_9544_0_1, dd_Smed_v6_9544_0_1, [RH, Score=224, Expect=1e-65]} {RNA1509_22408, RNA1509_31645} {RNA1310_13835, RNA1509_22408, RNA1509_31645} {RNA1509_22408, RNA1509_31645, RNA815_4510}
18. MligTC455_23491 83 1.73 Mlig455_059101

Neo: -

Age: -

 0.964 - - - - 0.964 - Mlig455_059101 {REF} {Length: 2808} {TRANSSPLICED} {RNA1509_38122} {RNA1310_8876.1} {RNA815_14615.1}
19. MligTC455_29886 979 20.4 Mlig455_029016

Neo: -

Age: logFC(26M/2M)=-0.339

Region-enriched R3: 1.707/0.00111

 0.964 - - - 0.964 - - Mlig455_029016 {REF} {Length: 2165} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=364.0]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=121, Expect=1e-30]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=304, Expect=3e-100]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=305, Expect=3e-100]} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1310_23805, RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541, RNA815_9290}
20. MligTC455_37964 3298 68.72 Mlig455_056045

Neo: -

Age: logFC(26M/2M)=1.465

 HSD17B4 0.964 - - - 0.964 - - Mlig455_056045 {REF} {Length: 2688} {Pfam: short chain dehydrogenase [PF00106.27, score=134.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=112.0]; MaoC like domain [PF01575.21, score=101.4]; SCP-2 sterol transfer family [PF02036.19, score=70.6]; KR domain [PF08659.12, score=53.8]} {Human: ENSG00000133835, HSD17B4, hydroxysteroid 17-beta dehydrogenase 4, [RH, Score=810, Expect=0.0]} {Mouse: ENSMUSG00000024507, Hsd17b4, hydroxysteroid (17-beta) dehydrogenase 4, [RH, Score=781, Expect=0.0]} {Dmel: FBgn0030731, Mfe2, peroxisomal Multifunctional enzyme type 2, [RH, Score=595, Expect=0.0]} {Celegans: WBGene00000991, dhs-28, DeHydrogenases, Short chain, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_5867_0_1, dd_Smed_v6_5867_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_9012} {RNA1310_590.1} {RNA815_2204}
21. MligTC455_04428 655 13.66 Mlig455_071088

Neo: -

Age: -

Region-enriched R4: 3.160/0.00859

 0.962 - - - 0.962 - - Mlig455_071088 {REF} {Length: 272} {NoTransDecoderORF} {RNA1509_284} {RNA1310_24413} {RNA815_6153}
22. MligTC455_52352 141 2.93 Mlig455_054504

Neo: -

Age: -

 PLPP6 0.961 - - - - - 0.961 Mlig455_054504 {REF} {Length: 3185} {Pfam: PAP2 superfamily [PF01569.23, score=54.7]; PAP2 superfamily [PF14378.8, score=30.1]} {Human: ENSG00000205808, PLPP6, phospholipid phosphatase 6, [Score=72.8, Expect=6e-15]} {Mouse: ENSMUSG00000040105, Plpp6, phospholipid phosphatase 6, [Score=73.9, Expect=1e-15]} {Dmel: FBgn0051717, CG31717, [Score=70.1, Expect=9e-15]} {Celegans: WBGene00020486, T13C5.6, [Score=77.0, Expect=1e-17]} {Smed: dd_Smed_v6_11684_0_1, dd_Smed_v6_11684_0_1, [Score=75.1, Expect=5e-17]} {RNA1509_56728} {RNA1310_49228} {RNA815_16579}
23. MligTC455_44645 563 11.72 Mlig455_070220

Neo: -

Age: -

 SLC28A1 0.959 - - - 0.959 - - Mlig455_070220 {REF} {Length: 2524} {Pfam: Na+ dependent nucleoside transporter C-terminus [PF07662.15, score=236.4]; Na+ dependent nucleoside transporter N-terminus [PF01773.22, score=73.8]; Nucleoside recognition [PF07670.16, score=23.7]} {Human: ENSG00000156222, SLC28A1, solute carrier family 28 member 1, [RH, Score=377, Expect=7e-123]; ENSG00000137860, SLC28A2, solute carrier family 28 member 2, [RH, Score=369, Expect=3e-119]} {Mouse: ENSMUSG00000027219, Slc28a2, solute carrier family 28 (sodium-coupled nucleoside transporter), member 2, [RH, Score=385, Expect=6e-126]; ENSMUSG00000025726, Slc28a1, solute carrier family 28 (sodium-coupled nucleoside transporter), member 1, [RH, Score=377, Expect=1e-122]} {Dmel: FBgn0025709, CNT2, Concentrative nucleoside transporter 2, [Score=300, Expect=5e-94]} {Celegans: WBGene00017868, slc-28.2, Sodium/nucleoside cotransporter, [RH, Score=240, Expect=2e-71]} {Smed: dd_Smed_v6_3508_0_1, dd_Smed_v6_3508_0_1, [Score=456, Expect=3e-154]} {RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1310_7732, RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1509_20711, RNA1509_21619, RNA1509_48971, RNA815_2578}
24. MligTC455_48283 909 18.94 Mlig455_026664

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.206

Region-enriched R4: 1.636/0.00109

 VMP1 0.958 - - - 0.958 - - Mlig455_026664 {REF} {Length: 4250} {Pfam: SAP domain [PF02037.29, score=41.2]; SNARE associated Golgi protein [PF09335.13, score=32.6]; SAP domain-containing new25 [PF18953.2, score=19.7]} {Human: ENSG00000062716, VMP1, vacuole membrane protein 1, [RH, Score=381, Expect=4e-128]} {Mouse: ENSMUSG00000018171, Vmp1, vacuole membrane protein 1, [RH, Score=388, Expect=7e-131]} {Dmel: FBgn0052675, Tango5, Transport and Golgi organization 5, [RH, Score=378, Expect=2e-125]} {Celegans: WBGene00012559, epg-3, Ectopic P granules protein 3, [RH, Score=371, Expect=6e-124]} {Smed: dd_Smed_v6_1156_0_1, dd_Smed_v6_1156_0_1, [RH, Score=281, Expect=6e-90]} {RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125} {RNA1310_6077, RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125} {RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125, RNA815_1510}
25. MligTC455_19715 467 9.74 Mlig455_002931

Neo: -

Age: logFC(26M/2M)=-0.732

Region-enriched R4: 1.523/0.02873

 RIDA 0.957 - - - 0.957 - - Mlig455_002931 {REF} {Length: 1022} {TRANSSPLICED} {Pfam: Endoribonuclease L-PSP [PF01042.23, score=99.4]} {Human: ENSG00000132541, RIDA, reactive intermediate imine deaminase A homolog, [Score=117, Expect=5e-34]} {Mouse: ENSMUSG00000022323, Rida, reactive intermediate imine deaminase A homolog, [Score=115, Expect=2e-33]} {Dmel: FBgn0086691, UK114, [Score=81.6, Expect=2e-20]} {Celegans: WBGene00016011, C23G10.2, RutC family protein C23G10.2, [Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1895_0_1, dd_Smed_v6_1895_0_1, [Score=118, Expect=4e-35]} {RNA1509_16898, RNA1509_22089} {RNA1310_27243, RNA1509_16898, RNA1509_22089} {RNA1509_16898, RNA1509_22089, RNA815_23611}
26. MligTC455_36954 2263 47.15 Mlig455_041278

Neo: -

Age: logFC(26M/2M)=-0.220

Region-enriched R3: 1.232/0.02876

 MARC1 0.957 - - - 0.957 - - Mlig455_041278 {REF} {Length: 2109} {Pfam: MOSC N-terminal beta barrel domain [PF03476.18, score=77.0]; MOSC domain [PF03473.19, score=67.6]} {Human: ENSG00000186205, MARC1, mitochondrial amidoxime reducing component 1, [RH, Score=114, Expect=1e-28]} {Mouse: ENSMUSG00000026621, Marc1, mitochondrial amidoxime reducing component 1, [RH, Score=118, Expect=3e-30]; ENSMUSG00000073481, Marc2, mitochondrial amidoxime reducing component 2, [RH, Score=116, Expect=2e-29]} {Dmel: FBgn0033451, CG1665, [RH, Score=81.6, Expect=3e-17]} {Celegans: WBGene00018758, F53E10.1, [RH, Score=98.2, Expect=4e-23]} {Smed: dd_Smed_v6_7493_0_1, dd_Smed_v6_7493_0_1, [Score=63.2, Expect=3e-11]} {RNA1509_12139, RNA1509_16934, RNA1509_25829, RNA1509_27068, RNA1509_4542} {RNA1310_14706.1, RNA1509_12139, RNA1509_16934, RNA1509_25829, RNA1509_27068, RNA1509_4542} {RNA1509_12139, RNA1509_16934, RNA1509_25829, RNA1509_27068, RNA1509_4542, RNA815_10847}
27. MligTC455_15352 3077 64.11 Mlig455_039852

Neo: -

Age: -

Region-enriched R4: 1.575/0.00036
Region-enriched R5: 1.301/0.00024

 SDR16C5 0.956 - - - 0.956 - - Mlig455_039852 {REF} {Length: 1435} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=165.9]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=115.3]; KR domain [PF08659.12, score=48.9]} {Human: ENSG00000170786, SDR16C5, short chain dehydrogenase/reductase family 16C member 5, [RH, Score=253, Expect=1e-82]} {Mouse: ENSMUSG00000028236, Sdr16c5, short chain dehydrogenase/reductase family 16C, member 5, [RH, Score=268, Expect=1e-88]} {Dmel: FBgn0031630, CG15629, [RH, Score=193, Expect=3e-59]} {Celegans: WBGene00000967, dhs-3, DeHydrogenases, Short chain, [RH, Score=247, Expect=1e-80]} {Smed: dd_Smed_v6_4834_0_2, dd_Smed_v6_4834_0_2, [RH, Score=234, Expect=8e-76]} {RNA1509_20131, RNA1509_41592, RNA1509_57893, RNA1509_57894, RNA1509_8825, RNA1509_9556} {RNA1310_22233, RNA1509_20131, RNA1509_41592, RNA1509_57893, RNA1509_57894, RNA1509_8825, RNA1509_9556} {RNA1509_20131, RNA1509_41592, RNA1509_57893, RNA1509_57894, RNA1509_8825, RNA1509_9556, RNA815_11357}
28. MligTC455_38598 960 20 Mlig455_045271, Mlig455_069192

Neo: -

Age: Down-Down-Up

 SYT14 0.956 - - - 0.956 - -

Mlig455_045271 {REF} {Length: 3033} {Pfam: C2 domain [PF00168.32, score=54.5]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [RH, Score=218, Expect=3e-65]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=216, Expect=5e-62]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [RH, Score=223, Expect=6e-66]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [Score=89.0, Expect=3e-19]} {Smed: dd_Smed_v6_9548_0_2, dd_Smed_v6_9548_0_2, [Score=160, Expect=1e-44]} {RNA1509_38023} {RNA1310_12668.1} {RNA815_11664.1}

Mlig455_069192 {REF} {Length: 3053} {Pfam: C2 domain [PF00168.32, score=54.5]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [RH, Score=219, Expect=2e-65]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=216, Expect=4e-62]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [RH, Score=223, Expect=2e-66]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [Score=88.6, Expect=4e-19]} {Smed: dd_Smed_v6_9548_0_2, dd_Smed_v6_9548_0_2, [Score=160, Expect=9e-45]} {RNA1509_38023, RNA1509_51042} {RNA1310_12668.1, RNA1509_38023, RNA1509_51042} {RNA1509_38023, RNA1509_51042, RNA815_11664.1}
29. MligTC455_04186 313 6.53 Mlig455_002354, Mlig455_053098

Neo: -

Age: -

 SLIT2 0.955 - - - - - 0.955

Mlig455_002354 {REF} {Length: 460} {Pfam: Leucine rich repeat [PF13855.8, score=128.4]; EGF-like domain [PF00008.29, score=121.4]; Human growth factor-like EGF [PF12661.9, score=72.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=72.5]; Laminin G domain [PF00054.25, score=61.8]; Laminin G domain [PF02210.26, score=58.2]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=47.1]; Leucine Rich Repeat [PF00560.35, score=30.8]; Leucine rich repeat N-terminal domain [PF01462.20, score=26.3]; Calcium-binding EGF domain [PF07645.17, score=24.9]; Leucine-rich repeat [PF14580.8, score=21.2]; EGF domain [PF12947.9, score=20.1]} {Human: ENSG00000145147, SLIT2, slit guidance ligand 2, [RH, Score=649, Expect=0.0]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [RH, Score=641, Expect=0.0]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [RH, Score=620, Expect=0.0]} {Dmel: FBgn0264089, sli, slit, [RH, Score=723, Expect=0.0]} {Celegans: WBGene00004854, slt-1, Slit homolog 1 protein, [RH, Score=593, Expect=0.0]} {Smed: dd_Smed_v6_12111_0_1, dd_Smed_v6_12111_0_1, [RH, Score=675, Expect=0.0]} {RNA1509_4387} {RNA1310_1314.1} {RNA815_367}

Mlig455_053098 {REF} {Length: 4484} {Pfam: Leucine rich repeat [PF13855.8, score=128.4]; EGF-like domain [PF00008.29, score=121.4]; Human growth factor-like EGF [PF12661.9, score=72.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=72.5]; Laminin G domain [PF00054.25, score=61.8]; Laminin G domain [PF02210.26, score=58.2]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=47.1]; Leucine Rich Repeat [PF00560.35, score=30.8]; Leucine rich repeat N-terminal domain [PF01462.20, score=26.3]; Calcium-binding EGF domain [PF07645.17, score=24.9]; Leucine-rich repeat [PF14580.8, score=21.2]; EGF domain [PF12947.9, score=20.1]} {Human: ENSG00000145147, SLIT2, slit guidance ligand 2, [RH, Score=649, Expect=0.0]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [RH, Score=641, Expect=0.0]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [RH, Score=620, Expect=0.0]} {Dmel: FBgn0264089, sli, slit, [RH, Score=723, Expect=0.0]} {Celegans: WBGene00004854, slt-1, Slit homolog 1 protein, [RH, Score=593, Expect=0.0]} {Smed: dd_Smed_v6_12111_0_1, dd_Smed_v6_12111_0_1, [RH, Score=675, Expect=0.0]} {RNA1509_4387, RNA1509_48290} {RNA1310_1314.1, RNA1509_4387, RNA1509_48290} {RNA1509_4387, RNA1509_48290, RNA815_367}
30. MligTC455_27011 404 8.43 Mlig455_032582

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.534

Region-enriched R5: 2.444/0.00062
Region-enriched R4: 2.178/0.03035

 0.955 - - - 0.955 - - Mlig455_032582 {REF} {Length: 7368} {Pfam: Fibronectin type III domain [PF00041.23, score=62.0]} {RNA1509_43177, RNA1509_4388, RNA1509_48867, RNA1509_57361, RNA1509_57435, RNA1509_57532} {RNA1310_213.1, RNA1509_43177, RNA1509_48867, RNA1509_57361, RNA1509_57435, RNA1509_57532} {RNA1509_43177, RNA1509_48867, RNA1509_57361, RNA1509_57435, RNA1509_57532, RNA815_43.1}
31. MligTC455_17024 361 7.51 Mlig455_036730

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.762/0.04763

 CTSO 0.954 - - - 0.954 - - Mlig455_036730 {REF} {Length: 2029} {TRANSSPLICED} {Pfam: Papain family cysteine protease [PF00112.25, score=166.5]; Peptidase C1-like family [PF03051.17, score=25.3]} {Human: ENSG00000263238, CTSO, cathepsin O, [RH, Score=169, Expect=1e-48]; ENSG00000256043, CTSO, cathepsin O, [RH, Score=169, Expect=1e-48]} {Mouse: ENSMUSG00000028015, Ctso, cathepsin O, [RH, Score=161, Expect=7e-46]} {Dmel: FBgn0260462, CG12163, [Score=130, Expect=3e-33]} {Celegans: WBGene00007055, tag-196, [Score=121, Expect=4e-30]} {Smed: dd_Smed_v6_456_0_1, dd_Smed_v6_456_0_1, [Score=124, Expect=2e-31]} {RNA1509_24611} {RNA1310_22386} {RNA815_10365}
32. MligTC455_37937 4015 83.65 Mlig455_035711, Mlig455_035797

Neo: -

Age: Down-Down-Up

Region-enriched R4: 1.404/0.03810
Region-enriched R5: 1.295/0.01501

 CHL1 0.954 - - - 0.954 - -

Mlig455_035711 {REF} {Length: 4194} {TRANSSPLICED} {Pfam: Bravo-like intracellular region [PF13882.8, score=60.6]; Immunoglobulin domain [PF13927.8, score=22.3]} {Human: ENSG00000134121, CHL1, cell adhesion molecule L1 like, [Score=55.5, Expect=2e-07]; ENSG00000091129, NRCAM, neuronal cell adhesion molecule, [Score=53.5, Expect=2e-06]} {Mouse: ENSMUSG00000020598, Nrcam, neuronal cell adhesion molecule, [RH, Score=51.6, Expect=9e-07]} {Smed: dd_Smed_v6_9155_0_2, dd_Smed_v6_9155_0_2, [RH, Score=53.9, Expect=3e-07]} {RNA1509_13489, RNA1509_1785, RNA1509_41860, RNA1509_6524} {RNA1310_5625, RNA1509_13489, RNA1509_41860, RNA1509_6524} {RNA1509_13489, RNA1509_41860, RNA1509_6524, RNA815_1660}

Mlig455_035797 {REF} {Length: 4434} {TRANSSPLICED} {Pfam: Bravo-like intracellular region [PF13882.8, score=60.6]; Immunoglobulin domain [PF13927.8, score=21.2]} {Human: ENSG00000134121, CHL1, cell adhesion molecule L1 like, [Score=55.5, Expect=3e-07]; ENSG00000091129, NRCAM, neuronal cell adhesion molecule, [Score=53.9, Expect=2e-06]} {Mouse: ENSMUSG00000020598, Nrcam, neuronal cell adhesion molecule, [RH, Score=52.0, Expect=8e-07]} {Smed: dd_Smed_v6_9155_0_2, dd_Smed_v6_9155_0_2, [RH, Score=53.9, Expect=3e-07]} {RNA1509_1785} {RNA1310_5625} {RNA815_1660}

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