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Results for MligTC455_52026

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_52026 1687 35.15 Mlig455_004669, Mlig455_004733, Mlig455_004832

Neo: -

Age: logFC(26M/2M)=0.290

Region-enriched R5: 1.467/0.04312

Mlig455_004669 {REF} {Length: 1728} {RNA1509_23759} {RNA1310_39844} {RNA815_18443.1}

Mlig455_004733 {REF} {Length: 2712} {RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1310_39844, RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1509_23759, RNA1509_38591, RNA1509_46380, RNA815_18443.1}

Mlig455_004832 {REF} {Length: 1806} {RNA1509_23759, RNA1509_55627} {RNA1310_39844, RNA1509_55627} {RNA1509_55627, RNA815_18443.1}

Cumulative graph for MligTC455_52026

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.257 5.318 0.79120 1.00000
RegionR2 -4.35 5.318 0.00000 0.00026
RegionR3 1.253 5.318 0.02471 0.26859
RegionR4 1.448 5.318 0.02811 0.12980
RegionR5 1.467 5.318 0.00669 0.04312
RegionR6 1.483 5.318 0.00929 0.16041
RegionR7 -1.556 5.318 0.04800 0.42109
RegionR8 -0.001 5.318 0.98987 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.187 5.318 0.89509 1.00000
RegenerationR2 1.921 5.318 0.03363 0.30267
RegenerationR3 -0.587 5.318 0.44013 0.82731
RegenerationR4 -0.365 5.318 0.63617 0.92575
RegenerationR5 0.361 5.318 0.62690 0.92139
RegenerationR6 0.296 5.318 0.68777 0.91757
RegenerationBL 0.221 5.318 0.75610 1.00000
RegenerationTP 0.362 5.318 0.66293 0.99541


Genes with expression patterns similar to MligTC455_52026

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_52026 1687 35.15 Mlig455_004669, Mlig455_004733, Mlig455_004832

Neo: -

Age: logFC(26M/2M)=0.290

Region-enriched R5: 1.467/0.04312

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_004669 {REF} {Length: 1728} {RNA1509_23759} {RNA1310_39844} {RNA815_18443.1}

Mlig455_004733 {REF} {Length: 2712} {RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1310_39844, RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1509_23759, RNA1509_38591, RNA1509_46380, RNA815_18443.1}

Mlig455_004832 {REF} {Length: 1806} {RNA1509_23759, RNA1509_55627} {RNA1310_39844, RNA1509_55627} {RNA1509_55627, RNA815_18443.1}
2. MligTC455_31181 3530 73.55 Mlig455_051856, Mlig455_051892

Neo: -

Age: -

Region-enriched R6: 1.979/0.00019
Region-enriched R5: 1.598/0.00061
Region-enriched R3: 1.383/0.02407
Region-enriched R4: 1.335/0.03212

ANPEP, ERAP1 3.344 0.751 - - 0.978 0.895 0.720

Mlig455_051856 {REF} {Length: 5257} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=263.7]; Peptidase family M1 domain [PF01433.22, score=247.0]; Peptidase M1 N-terminal domain [PF17900.3, score=143.0]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [RH, Score=578, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=565, Expect=0.0]} {Dmel: FBgn0039640, CG14516, [RH, Score=545, Expect=4e-178]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [RH, Score=438, Expect=9e-138]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [RH, Score=644, Expect=0.0]} {RNA1509_14294, RNA1509_1573, RNA1509_20439} {RNA1310_1662.1, RNA1509_14294, RNA1509_20439} {RNA1509_14294, RNA1509_20439, RNA815_486.1}

Mlig455_051892 {REF} {Length: 3530} {Pfam: Peptidase family M1 domain [PF01433.22, score=52.4]; ERAP1-like C-terminal domain [PF11838.10, score=39.9]; FimH, mannose binding [PF09160.12, score=18.4]} {Human: ENSG00000164307, ERAP1, endoplasmic reticulum aminopeptidase 1, [Score=108, Expect=5e-26]; ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=105, Expect=3e-25]} {Mouse: ENSMUSG00000021583, Erap1, endoplasmic reticulum aminopeptidase 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0039656, CG11951, [Score=92.0, Expect=9e-21]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=100, Expect=7e-24]} {Smed: dd_Smed_v6_1249_0_1, dd_Smed_v6_1249_0_1, [Score=95.9, Expect=2e-22]} {RNA1509_13872} {RNA1310_1662.1} {RNA815_3255}
3. MligTC455_15783 5345 111.36 Mlig455_025807, Mlig455_025814

Neo: -

Age: -

Region-enriched R4: 1.633/0.00032
Region-enriched R5: 1.583/0.00001
Region-enriched R6: 1.083/0.03690

GULP1 3.3 0.771 0.834 - 0.966 0.729 -

Mlig455_025807 {REF} {Length: 1817} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.3, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]; ENSMUSG00000024219, Anks1, ankyrin repeat and SAM domain containing 1, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0029092, ced-6, [RH, Score=69.7, Expect=1e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=49.3, Expect=3e-06]} {RNA1509_14211, RNA1509_2504} {RNA1310_16087, RNA1509_14211, RNA1509_2504} {RNA1509_14211, RNA1509_2504, RNA815_6763}

Mlig455_025814 {REF} {Length: 1818} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.7, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]} {Dmel: FBgn0029092, ced-6, [RH, Score=68.2, Expect=3e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=47.8, Expect=8e-06]} {RNA1509_2504, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1310_16087, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1509_44856, RNA1509_48464, RNA1509_9772, RNA815_6763}
4. MligTC455_18116 1101 22.93 Mlig455_034507

Neo: -

Age: -

Region-enriched R6: 2.069/0.00170
Region-enriched R5: 1.877/0.00089

AP2S1 3.227 - 0.764 - 0.959 0.781 0.723 Mlig455_034507 {REF} {Length: 3004} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=204.0]} {Human: ENSG00000042753, AP2S1, adaptor related protein complex 2 subunit sigma 1, [RH, Score=269, Expect=3e-94]} {Mouse: ENSMUSG00000008036, Ap2s1, adaptor-related protein complex 2, sigma 1 subunit, [RH, Score=269, Expect=2e-94]} {Dmel: FBgn0043012, AP-2sigma, Adaptor Protein complex 2, sigma subunit, [RH, Score=265, Expect=7e-93]} {Celegans: WBGene00000157, aps-2, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=268, Expect=2e-94]} {Smed: dd_Smed_v6_3529_0_1, dd_Smed_v6_3529_0_1, [RH, Score=257, Expect=6e-90]} {RNA1509_11642, RNA1509_3682, RNA1509_37240, RNA1509_53443, RNA1509_60138, RNA1509_8028} {RNA1310_34747, RNA1509_11642, RNA1509_3682, RNA1509_53443, RNA1509_60138, RNA1509_8028} {RNA1509_11642, RNA1509_3682, RNA1509_53443, RNA1509_60138, RNA1509_8028, RNA815_7668.1}
5. MligTC455_18117 1092 22.75 Mlig455_066275

Neo: -

Age: logFC(26M/2M)=0.355

Region-enriched R6: 2.041/0.00226
Region-enriched R5: 1.905/0.00060

AP2S1 3.221 - 0.766 - 0.959 0.774 0.722 Mlig455_066275 {REF} {Length: 1943} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=204.0]} {Human: ENSG00000042753, AP2S1, adaptor related protein complex 2 subunit sigma 1, [RH, Score=269, Expect=3e-94]} {Mouse: ENSMUSG00000008036, Ap2s1, adaptor-related protein complex 2, sigma 1 subunit, [RH, Score=269, Expect=2e-94]} {Dmel: FBgn0043012, AP-2sigma, Adaptor Protein complex 2, sigma subunit, [RH, Score=265, Expect=7e-93]} {Celegans: WBGene00000157, aps-2, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=268, Expect=2e-94]} {Smed: dd_Smed_v6_3529_0_1, dd_Smed_v6_3529_0_1, [RH, Score=257, Expect=6e-90]} {RNA1509_11775, RNA1509_37240} {RNA1310_34747, RNA1509_11775, RNA1509_37240} {RNA1509_11775, RNA1509_37240, RNA815_7668.1}
6. MligTC455_45420 2046 42.62 Mlig455_056064, Mlig455_061586

Neo: -

Age: -

Region-enriched R3: 2.079/0.03891

2.761 0.867 - - 0.955 - 0.939

Mlig455_056064 {REF} {Length: 1343} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_9020} {RNA1310_25351.3} {RNA815_8070}

Mlig455_061586 {REF} {Length: 1849} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_48946, RNA1509_9020} {RNA1310_25351.3, RNA1509_48946, RNA1509_9020} {RNA1509_48946, RNA1509_9020, RNA815_8070}
7. MligTC455_50736 5253 109.44 Mlig455_030264

Neo: -

Age: -

Region-enriched R6: 1.447/0.04006

2.731 0.896 - - 0.954 0.881 - Mlig455_030264 {REF} {Length: 442} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_524} {RNA1310_31841} {RNA815_1325}
8. MligTC455_39350 538 11.21 Mlig455_023484

Neo: -

Age: Down-Up-Down

Region-enriched R4: 3.492/0.00082
Region-enriched R5: 2.753/0.00156

RAB8B 2.675 - - - 0.950 0.782 0.943 Mlig455_023484 {REF} {Length: 1074} {Pfam: Ras family [PF00071.24, score=174.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.8]; ADP-ribosylation factor family [PF00025.23, score=55.3]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=152, Expect=1e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=2e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=2e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=152, Expect=6e-46]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=147, Expect=3e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=145, Expect=5e-43]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=5e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=5e-52]} {RNA1509_19859, RNA1509_27459} {RNA1310_37116, RNA1509_27459} {RNA1509_27459, RNA815_17007}
9. MligTC455_53812 2315 48.24 Mlig455_015129

Neo: -

Age: logFC(26M/2M)=-2.651

Region-enriched R6: 1.986/0.00003
Region-enriched R5: 1.574/0.00020
Region-enriched R3: 1.221/0.03544

2.609 - - - 0.939 0.717 0.953 Mlig455_015129 {REF} {Length: 705} {NoTransDecoderORF} {RNA1509_178} {RNA1310_14124} {RNA815_48259}
10. MligTC455_27407 2071 43.14 Mlig455_040794

Neo: -

Age: -

CLTC 2.601 0.742 - - 0.892 - 0.967 Mlig455_040794 {REF} {Length: 6145} {Pfam: Region in Clathrin and VPS [PF00637.22, score=643.9]; Clathrin propeller repeat [PF01394.22, score=127.7]; Clathrin-H-link [PF13838.8, score=115.3]; Clathrin, heavy-chain linker [PF09268.12, score=39.2]; Coatomer WD associated region [PF04053.16, score=32.1]; Tetratricopeptide repeat [PF13428.8, score=19.9]} {Human: ENSG00000141367, CLTC, clathrin heavy chain, [RH, Score=2641, Expect=0.0]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [RH, Score=2640, Expect=0.0]} {Dmel: FBgn0000319, Chc, Clathrin heavy chain, [RH, Score=2533, Expect=0.0]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [RH, Score=2347, Expect=0.0]} {Smed: dd_Smed_v6_59_0_1, dd_Smed_v6_59_0_1, [RH, Score=2675, Expect=0.0]} {RNA1509_23463, RNA1509_55839, RNA1509_592, RNA1509_6769} {RNA1310_523.1, RNA1509_23463, RNA1509_55839, RNA1509_592, RNA1509_6769} {RNA1509_23463, RNA1509_55839, RNA1509_592, RNA1509_6769, RNA815_198.1}
11. MligTC455_27408 2056 42.83 Mlig455_064632

Neo: -

Age: Down-Up-Up

CLTC 2.593 0.739 - - 0.885 - 0.969 Mlig455_064632 {REF} {Length: 1348} {Pfam: Region in Clathrin and VPS [PF00637.22, score=107.0]} {Human: ENSG00000141367, CLTC, clathrin heavy chain, [Score=298, Expect=2e-97]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [Score=298, Expect=3e-92]} {Dmel: FBgn0000319, Chc, Clathrin heavy chain, [Score=280, Expect=2e-86]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=259, Expect=3e-79]} {Smed: dd_Smed_v6_59_0_2, dd_Smed_v6_59_0_2, [Score=310, Expect=4e-97]} {RNA1509_17759, RNA1509_38056, RNA1509_55839} {RNA1310_523.1, RNA1509_17759, RNA1509_38056} {RNA1509_17759, RNA1509_38056, RNA815_3155}
12. MligTC455_43156 30659 638.72 Mlig455_013212, Mlig455_013235, Mlig455_013307

Neo: -

Age: logFC(26M/2M)=-0.210

Region-enriched R6: 1.505/0.00540
Region-enriched R5: 1.426/0.00133
Region-enriched R4: 1.190/0.03651

2.592 0.740 - - 0.979 0.873 -

Mlig455_013212 {REF} {Length: 1340} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=78.1]; Methyltransferase domain [PF13649.8, score=73.6]; Methyltransferase domain [PF13489.8, score=61.5]; Methyltransferase domain [PF08242.14, score=51.0]; Methyltransferase domain [PF13847.8, score=50.3]; ubiE/COQ5 methyltransferase family [PF01209.20, score=50.2]; Mycolic acid cyclopropane synthetase [PF02353.22, score=42.9]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=23.1]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=22.1]; Methyltransferase small domain [PF05175.16, score=21.3]; Tellurite resistance protein TehB [PF03848.16, score=20.1]} {Dmel: FBgn0032922, CG9249, [Score=47.8, Expect=4e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=182, Expect=1e-54]} {RNA1509_20289, RNA1509_5276, RNA1509_6525} {RNA1310_20797, RNA1509_20289, RNA1509_5276} {RNA1509_20289, RNA1509_5276, RNA815_10580.1}

Mlig455_013235 {REF} {Length: 1347} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=77.6]; Methyltransferase domain [PF13649.8, score=73.4]; Methyltransferase domain [PF13489.8, score=59.4]; Methyltransferase domain [PF08242.14, score=50.7]; Methyltransferase domain [PF13847.8, score=50.0]; ubiE/COQ5 methyltransferase family [PF01209.20, score=49.1]; Mycolic acid cyclopropane synthetase [PF02353.22, score=41.7]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=21.8]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=21.4]; Methyltransferase small domain [PF05175.16, score=19.5]} {Dmel: FBgn0032922, CG9249, [Score=48.1, Expect=3e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=181, Expect=4e-54]} {RNA1509_2488, RNA1509_52745, RNA1509_6525} {RNA1310_20797, RNA1509_2488, RNA1509_52745, RNA1509_6525} {RNA1509_2488, RNA1509_52745, RNA1509_6525, RNA815_10580.1}

Mlig455_013307 {REF} {Length: 1338} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=78.1]; Methyltransferase domain [PF13649.8, score=73.6]; Methyltransferase domain [PF13489.8, score=61.5]; Methyltransferase domain [PF08242.14, score=51.0]; Methyltransferase domain [PF13847.8, score=50.3]; ubiE/COQ5 methyltransferase family [PF01209.20, score=50.2]; Mycolic acid cyclopropane synthetase [PF02353.22, score=42.9]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=23.1]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=22.1]; Methyltransferase small domain [PF05175.16, score=21.3]; Tellurite resistance protein TehB [PF03848.16, score=20.1]} {Dmel: FBgn0032922, CG9249, [Score=47.8, Expect=4e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=182, Expect=1e-54]} {RNA1509_6525} {RNA1310_20797} {RNA815_10580.1}
13. MligTC455_34754 1515 31.57 Mlig455_040390, Mlig455_040396

Neo: -

Age: -

Region-enriched R5: 1.522/0.00861

PFKM 2.57 0.782 - - 0.963 0.825 -

Mlig455_040390 {REF} {Length: 5737} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=551.3]; Integrase core domain [PF00665.28, score=28.9]} {Human: ENSG00000152556, PFKM, phosphofructokinase, muscle, [Score=511, Expect=8e-163]; ENSG00000067057, PFKP, phosphofructokinase, platelet, [Score=501, Expect=7e-160]; ENSG00000141959, PFKL, phosphofructokinase, liver type, [Score=495, Expect=9e-158]} {Mouse: ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [Score=508, Expect=8e-163]; ENSMUSG00000020277, Pfkl, phosphofructokinase, liver, B-type, [Score=498, Expect=8e-159]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [Score=494, Expect=1e-157]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [Score=517, Expect=4e-166]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [Score=501, Expect=5e-160]} {Smed: dd_Smed_v6_3613_0_1, dd_Smed_v6_3613_0_1, [Score=571, Expect=0.0]} {RNA1509_11643} {RNA1310_2251.4} {RNA815_8327}

Mlig455_040396 {REF} {Length: 3871} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=611.5]} {Human: ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=837, Expect=0.0]} {Mouse: ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=832, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=814, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [Score=826, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=810, Expect=0.0]} {Smed: dd_Smed_v6_3613_0_1, dd_Smed_v6_3613_0_1, [Score=864, Expect=0.0]} {RNA1509_11643, RNA1509_13268, RNA1509_33375, RNA1509_53165} {RNA1310_2251.2, RNA1509_13268, RNA1509_33375, RNA1509_53165} {RNA1509_13268, RNA1509_33375, RNA1509_53165, RNA815_2567}
14. MligTC455_43797 2681 55.85 Mlig455_051343

Neo: -

Age: logFC(26M/2M)=0.181

Region-enriched R5: 1.067/0.00046

SHMT2 2.529 0.710 - - 0.967 0.852 - Mlig455_051343 {REF} {Length: 1803} {TRANSSPLICED} {Pfam: Serine hydroxymethyltransferase [PF00464.21, score=614.7]} {Human: ENSG00000182199, SHMT2, serine hydroxymethyltransferase 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000025403, Shmt2, serine hydroxymethyltransferase 2 (mitochondrial), [RH, Score=657, Expect=0.0]} {Dmel: FBgn0029823, Shmt, Serine hydroxymethyl transferase, [RH, Score=594, Expect=0.0]} {Celegans: WBGene00003214, mel-32, Serine hydroxymethyltransferase, [RH, Score=567, Expect=0.0]} {Smed: dd_Smed_v6_7793_0_1, dd_Smed_v6_7793_0_1, [RH, Score=638, Expect=0.0]} {RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642} {RNA1310_15013, RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642} {RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642, RNA815_5372}
15. MligTC455_22295 61 1.27 Mlig455_013847

Neo: -

Age: -

Region-enriched R4: 4.322/0.00351

2.498 0.761 - - 0.956 0.781 - Mlig455_013847 {REF} {Length: 739} {RNA1509_27316} {RNA1310_79145} {RNA815_31484}
16. MligTC455_44645 563 11.72 Mlig455_070220

Neo: -

Age: -

SLC28A1 2.488 0.736 - - 0.970 0.782 - Mlig455_070220 {REF} {Length: 2524} {Pfam: Na+ dependent nucleoside transporter C-terminus [PF07662.15, score=236.4]; Na+ dependent nucleoside transporter N-terminus [PF01773.22, score=73.8]; Nucleoside recognition [PF07670.16, score=23.7]} {Human: ENSG00000156222, SLC28A1, solute carrier family 28 member 1, [RH, Score=377, Expect=7e-123]; ENSG00000137860, SLC28A2, solute carrier family 28 member 2, [RH, Score=369, Expect=3e-119]} {Mouse: ENSMUSG00000027219, Slc28a2, solute carrier family 28 (sodium-coupled nucleoside transporter), member 2, [RH, Score=385, Expect=6e-126]; ENSMUSG00000025726, Slc28a1, solute carrier family 28 (sodium-coupled nucleoside transporter), member 1, [RH, Score=377, Expect=1e-122]} {Dmel: FBgn0025709, CNT2, Concentrative nucleoside transporter 2, [Score=300, Expect=5e-94]} {Celegans: WBGene00017868, slc-28.2, Sodium/nucleoside cotransporter, [RH, Score=240, Expect=2e-71]} {Smed: dd_Smed_v6_3508_0_1, dd_Smed_v6_3508_0_1, [Score=456, Expect=3e-154]} {RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1310_7732, RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1509_20711, RNA1509_21619, RNA1509_48971, RNA815_2578}
17. MligTC455_48283 909 18.94 Mlig455_026664

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.206

Region-enriched R4: 1.636/0.00109

VMP1 2.488 0.785 - - 0.950 0.753 - Mlig455_026664 {REF} {Length: 4250} {Pfam: SAP domain [PF02037.29, score=41.2]; SNARE associated Golgi protein [PF09335.13, score=32.6]; SAP domain-containing new25 [PF18953.2, score=19.7]} {Human: ENSG00000062716, VMP1, vacuole membrane protein 1, [RH, Score=381, Expect=4e-128]} {Mouse: ENSMUSG00000018171, Vmp1, vacuole membrane protein 1, [RH, Score=388, Expect=7e-131]} {Dmel: FBgn0052675, Tango5, Transport and Golgi organization 5, [RH, Score=378, Expect=2e-125]} {Celegans: WBGene00012559, epg-3, Ectopic P granules protein 3, [RH, Score=371, Expect=6e-124]} {Smed: dd_Smed_v6_1156_0_1, dd_Smed_v6_1156_0_1, [RH, Score=281, Expect=6e-90]} {RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125} {RNA1310_6077, RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125} {RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125, RNA815_1510}
18. MligTC455_35519 1708 35.59 Mlig455_014621

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.589

Region-enriched R4: 1.911/0.00012
Region-enriched R3: 1.380/0.00213
Region-enriched R5: 1.309/0.00075

SLC44A2 2.455 0.722 0.771 - 0.962 - - Mlig455_014621 {REF} {Length: 3582} {Pfam: Plasma-membrane choline transporter [PF04515.14, score=313.8]} {Human: ENSG00000129353, SLC44A2, solute carrier family 44 member 2, [Score=436, Expect=1e-142]} {Mouse: ENSMUSG00000057193, Slc44a2, solute carrier family 44, member 2, [Score=451, Expect=7e-149]} {Dmel: FBgn0039637, Ctl2, Choline transporter-like 2, [Score=315, Expect=4e-96]} {Celegans: WBGene00018037, chtl-1, Choline transporter-like protein 1, [Score=373, Expect=1e-118]} {Smed: dd_Smed_v6_6488_0_1, dd_Smed_v6_6488_0_1, [Score=434, Expect=7e-142]} {RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1310_8213, RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1509_14161, RNA1509_56009, RNA1509_8961, RNA815_109}
19. MligTC455_52915 17827 371.4 Mlig455_014224

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.310

AHCY 2.441 0.784 - - 0.954 0.703 - Mlig455_014224 {REF} {Length: 2060} {Pfam: S-adenosyl-L-homocysteine hydrolase [PF05221.19, score=455.6]; S-adenosyl-L-homocysteine hydrolase, NAD binding domain [PF00670.23, score=269.8]; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=33.8]; Acetohydroxy acid isomeroreductase, NADPH-binding domain [PF07991.14, score=26.1]; Putative NAD(P)-binding [PF13241.8, score=20.1]} {Human: ENSG00000101444, AHCY, adenosylhomocysteinase, [RH, Score=683, Expect=0.0]} {Mouse: ENSMUSG00000048087, Gm4737, predicted gene 4737, [RH, Score=676, Expect=0.0]; ENSMUSG00000027597, Ahcy, S-adenosylhomocysteine hydrolase, [RH, Score=676, Expect=0.0]} {Dmel: FBgn0014455, Ahcy, Adenosylhomocysteinase, [RH, Score=717, Expect=0.0]} {Celegans: WBGene00019322, ahcy-1, Adenosylhomocysteinase, [RH, Score=723, Expect=0.0]} {Smed: dd_Smed_v6_526_0_1, dd_Smed_v6_526_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_1247, RNA1509_1422, RNA1509_1799, RNA1509_255} {RNA1310_14138.1, RNA1509_1247, RNA1509_1422, RNA1509_1799, RNA1509_255} {RNA1509_1247, RNA1509_1422, RNA1509_1799, RNA1509_255, RNA815_4519.1}
20. MligTC455_52916 35102 731.3 Mlig455_014202, Mlig455_070564

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.365

AHCY 2.441 0.782 - - 0.954 0.705 -

Mlig455_014202 {REF} {Length: 1594} {Pfam: S-adenosyl-L-homocysteine hydrolase [PF05221.19, score=282.2]; S-adenosyl-L-homocysteine hydrolase, NAD binding domain [PF00670.23, score=270.5]; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=34.3]; Acetohydroxy acid isomeroreductase, NADPH-binding domain [PF07991.14, score=26.5]; Putative NAD(P)-binding [PF13241.8, score=20.4]; TrkA-N domain [PF02254.20, score=19.0]} {Human: ENSG00000101444, AHCY, adenosylhomocysteinase, [Score=544, Expect=0.0]} {Mouse: ENSMUSG00000027597, Ahcy, S-adenosylhomocysteine hydrolase, [Score=539, Expect=0.0]; ENSMUSG00000048087, Gm4737, predicted gene 4737, [Score=539, Expect=0.0]} {Dmel: FBgn0014455, Ahcy, Adenosylhomocysteinase, [Score=564, Expect=0.0]} {Celegans: WBGene00019322, ahcy-1, Adenosylhomocysteinase, [Score=572, Expect=0.0]} {Smed: dd_Smed_v6_526_0_1, dd_Smed_v6_526_0_1, [Score=602, Expect=0.0]} {RNA1509_1422} {RNA1310_14138.1} {RNA815_4519.1}

Mlig455_070564 {REF} {Length: 1656} {Pfam: S-adenosyl-L-homocysteine hydrolase [PF05221.19, score=285.5]; S-adenosyl-L-homocysteine hydrolase, NAD binding domain [PF00670.23, score=270.5]; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=34.3]; Acetohydroxy acid isomeroreductase, NADPH-binding domain [PF07991.14, score=26.5]; Putative NAD(P)-binding [PF13241.8, score=20.5]; TrkA-N domain [PF02254.20, score=19.0]} {Human: ENSG00000101444, AHCY, adenosylhomocysteinase, [Score=544, Expect=0.0]} {Mouse: ENSMUSG00000048087, Gm4737, predicted gene 4737, [Score=536, Expect=0.0]; ENSMUSG00000027597, Ahcy, S-adenosylhomocysteine hydrolase, [Score=536, Expect=0.0]} {Dmel: FBgn0014455, Ahcy, Adenosylhomocysteinase, [Score=561, Expect=0.0]} {Celegans: WBGene00019322, ahcy-1, Adenosylhomocysteinase, [Score=577, Expect=0.0]} {Smed: dd_Smed_v6_526_0_1, dd_Smed_v6_526_0_1, [Score=605, Expect=0.0]} {RNA1509_1422, RNA1509_16178, RNA1509_19193} {RNA1310_14138.1, RNA1509_16178, RNA1509_19193} {RNA1509_16178, RNA1509_19193, RNA815_4519.1}
21. MligTC455_48316 736 15.33 Mlig455_024236

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.170

2.4 - - - 0.722 0.714 0.964 Mlig455_024236 {REF} {Length: 1366} {Pfam: NADH-ubiquinone reductase complex 1 MLRQ subunit [PF06522.13, score=19.0]} {RNA1509_23312, RNA1509_24608, RNA1509_52164} {RNA1310_29405, RNA1509_23312, RNA1509_24608, RNA1509_52164} {RNA1509_23312, RNA1509_24608, RNA1509_52164, RNA815_17291.1}
22. MligTC455_18597 2002 41.7 Mlig455_008723, Mlig455_063593

Neo: -

Age: -

Region-enriched R5: 1.210/0.02582

AGPS 1.906 - - - 0.988 0.918 -

Mlig455_008723 {REF} {Length: 3049} {TRANSSPLICED} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=183.8]; FAD binding domain [PF01565.25, score=116.9]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [RH, Score=770, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [RH, Score=771, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [RH, Score=669, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [RH, Score=702, Expect=0.0]} {RNA1509_6531} {RNA1310_6470.2, RNA1509_6531} {RNA1509_6531, RNA815_2634}

Mlig455_063593 {REF} {Length: 3191} {TRANSSPLICED} {Pfam: FAD binding domain [PF01565.25, score=116.1]; FAD linked oxidases, C-terminal domain [PF02913.21, score=111.2]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [Score=683, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [Score=685, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [Score=566, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [Score=583, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [Score=620, Expect=0.0]} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA1509_6531} {RNA1310_6470.2, RNA1509_28418, RNA1509_50386, RNA1509_53669} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA815_2634}
23. MligTC455_39351 815 16.99 Mlig455_068114

Neo: -

Age: -

RAB8B 1.902 - - - 0.970 - 0.932 Mlig455_068114 {REF} {Length: 1704} {Pfam: Ras family [PF00071.24, score=174.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.7]; ADP-ribosylation factor family [PF00025.23, score=55.4]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=151, Expect=2e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [Score=145, Expect=6e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=3e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=3e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=151, Expect=1e-45]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=148, Expect=2e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=144, Expect=2e-42]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [Score=144, Expect=3e-42]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=6e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=6e-52]} {RNA1509_18167, RNA1509_19859} {RNA1310_37116, RNA1509_18167, RNA1509_19859} {RNA1509_18167, RNA1509_19859, RNA815_17007}
24. MligTC455_34755 1776 36.99 Mlig455_050399

Neo: -

Age: -

PFKM 1.842 - - - 0.974 0.868 - Mlig455_050399 {REF} {Length: 3919} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=609.5]} {Human: ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=830, Expect=0.0]} {Mouse: ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=826, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=805, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [Score=834, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=810, Expect=0.0]} {Smed: dd_Smed_v6_3613_0_1, dd_Smed_v6_3613_0_1, [Score=864, Expect=0.0]} {RNA1509_45109, RNA1509_4935} {RNA1310_2251.3, RNA1509_45109} {RNA1509_45109, RNA815_2567}
25. MligTC455_27011 404 8.43 Mlig455_032582

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.534

Region-enriched R5: 2.444/0.00062
Region-enriched R4: 2.178/0.03035

1.812 - - - 0.951 0.861 - Mlig455_032582 {REF} {Length: 7368} {Pfam: Fibronectin type III domain [PF00041.23, score=62.0]} {RNA1509_43177, RNA1509_4388, RNA1509_48867, RNA1509_57361, RNA1509_57435, RNA1509_57532} {RNA1310_213.1, RNA1509_43177, RNA1509_48867, RNA1509_57361, RNA1509_57435, RNA1509_57532} {RNA1509_43177, RNA1509_48867, RNA1509_57361, RNA1509_57435, RNA1509_57532, RNA815_43.1}
26. MligTC455_47202 347 7.23 Mlig455_067347

Neo: -

Age: -

1.79 - - - 0.965 0.825 - Mlig455_067347 {REF} {Length: 3673} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=78.5]; C2H2 type zinc-finger (2 copies) [PF12756.9, score=26.9]; C2H2-type zinc finger [PF13894.8, score=21.6]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=21.2]} {Dmel: FBgn0028979, tio, tiptop, [RH, Score=75.1, Expect=3e-13]} {Smed: dd_Smed_v6_9287_0_1, dd_Smed_v6_9287_0_1, [Score=131, Expect=9e-31]} {RNA1509_33943} {RNA1310_12382} {RNA815_29092}
27. MligTC455_45275 384 8 Mlig455_037525

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.804

Region-enriched R4: 2.211/0.00561

1.787 - - - 0.963 0.824 - Mlig455_037525 {REF} {Length: 1617} {Pfam: HYD1 signature containing ADP-ribosyltransferase [PF15633.8, score=44.2]} {RNA1509_38410, RNA1509_7973} {RNA1310_28627, RNA1509_38410, RNA1509_7973} {RNA1509_38410, RNA1509_7973, RNA815_9390.1}
28. MligTC455_17024 361 7.51 Mlig455_036730

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.762/0.04763

CTSO 1.774 0.824 - - 0.950 - - Mlig455_036730 {REF} {Length: 2029} {TRANSSPLICED} {Pfam: Papain family cysteine protease [PF00112.25, score=166.5]; Peptidase C1-like family [PF03051.17, score=25.3]} {Human: ENSG00000263238, CTSO, cathepsin O, [RH, Score=169, Expect=1e-48]; ENSG00000256043, CTSO, cathepsin O, [RH, Score=169, Expect=1e-48]} {Mouse: ENSMUSG00000028015, Ctso, cathepsin O, [RH, Score=161, Expect=7e-46]} {Dmel: FBgn0260462, CG12163, [Score=130, Expect=3e-33]} {Celegans: WBGene00007055, tag-196, [Score=121, Expect=4e-30]} {Smed: dd_Smed_v6_456_0_1, dd_Smed_v6_456_0_1, [Score=124, Expect=2e-31]} {RNA1509_24611} {RNA1310_22386} {RNA815_10365}
29. MligTC455_17185 1203 25.06 Mlig455_043379, Mlig455_043547

Neo: -

Age: -

Region-enriched R3: 2.698/0.00014
Region-enriched R6: 2.303/0.00650

1.767 0.810 - - - - 0.957

Mlig455_043379 {REF} {Length: 1593} {Pfam: YhhN family [PF07947.16, score=80.0]} {Dmel: FBgn0039681, CG7582, [Score=52.4, Expect=6e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_28364} {RNA1310_11695.1} {RNA815_14610}

Mlig455_043547 {REF} {Length: 2226} {Pfam: YhhN family [PF07947.16, score=80.0]} {Dmel: FBgn0039681, CG7582, [Score=52.4, Expect=6e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_28364, RNA1509_37355} {RNA1310_11695.1, RNA1509_37355} {RNA1509_37355, RNA815_14610}
30. MligTC455_30395 108 2.25 Mlig455_070650

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.875

ALDH18A1 1.764 - - - 0.805 0.959 - Mlig455_070650 {REF} {Length: 3857} {Pfam: Amino acid kinase family [PF00696.30, score=138.7]; Aldehyde dehydrogenase family [PF00171.24, score=57.0]} {Human: ENSG00000059573, ALDH18A1, aldehyde dehydrogenase 18 family member A1, [RH, Score=852, Expect=0.0]} {Mouse: ENSMUSG00000025007, Aldh18a1, aldehyde dehydrogenase 18 family, member A1, [RH, Score=857, Expect=0.0]} {Dmel: FBgn0037146, CG7470, [RH, Score=815, Expect=0.0]} {Celegans: WBGene00011938, alh-13, Probable delta-1-pyrroline-5-carboxylate synthase Glutamate 5-kinase Gamma-glutamyl phosphate reductase, [RH, Score=811, Expect=0.0]} {Smed: dd_Smed_v6_1060_0_1, dd_Smed_v6_1060_0_1, [RH, Score=916, Expect=0.0]} {RNA1509_1671} {RNA1310_2413} {RNA815_1917}
31. MligTC455_42649 1111 23.15 Mlig455_033920

Neo: -

Age: logFC(26M/2M)=0.288

TPTE2 1.756 0.784 - - 0.972 - - Mlig455_033920 {REF} {Length: 2398} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=66.0]; Ion transport protein [PF00520.33, score=35.9]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=28.9]; Protein-tyrosine phosphatase [PF00102.29, score=24.5]; Inositol hexakisphosphate [PF14566.8, score=22.0]} {Human: ENSG00000132958, TPTE2, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2, [RH, Score=373, Expect=6e-124]} {Mouse: ENSMUSG00000031481, Tpte, transmembrane phosphatase with tensin homology, [RH, Score=384, Expect=1e-126]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=171, Expect=9e-48]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=137, Expect=5e-34]} {Smed: dd_Smed_v6_4925_0_2, dd_Smed_v6_4925_0_2, [RH, Score=424, Expect=7e-145]} {RNA1509_26060, RNA1509_6952} {RNA1310_16625.1, RNA1509_26060, RNA1509_6952} {RNA1509_26060, RNA1509_6952, RNA815_5966}
32. MligTC455_19715 467 9.74 Mlig455_002931

Neo: -

Age: logFC(26M/2M)=-0.732

Region-enriched R4: 1.523/0.02873

RIDA 1.754 - - - 0.979 0.775 - Mlig455_002931 {REF} {Length: 1022} {TRANSSPLICED} {Pfam: Endoribonuclease L-PSP [PF01042.23, score=99.4]} {Human: ENSG00000132541, RIDA, reactive intermediate imine deaminase A homolog, [Score=117, Expect=5e-34]} {Mouse: ENSMUSG00000022323, Rida, reactive intermediate imine deaminase A homolog, [Score=115, Expect=2e-33]} {Dmel: FBgn0086691, UK114, [Score=81.6, Expect=2e-20]} {Celegans: WBGene00016011, C23G10.2, RutC family protein C23G10.2, [Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1895_0_1, dd_Smed_v6_1895_0_1, [Score=118, Expect=4e-35]} {RNA1509_16898, RNA1509_22089} {RNA1310_27243, RNA1509_16898, RNA1509_22089} {RNA1509_16898, RNA1509_22089, RNA815_23611}
33. MligTC455_47137 1792 37.33 Mlig455_044379

Neo: -

Age: -

Region-enriched R3: 2.390/0.00000

SLC5A11 1.749 - - - 0.951 - 0.798 Mlig455_044379 {REF} {Length: 3271} {Pfam: Sodium:solute symporter family [PF00474.19, score=378.5]} {Human: ENSG00000158865, SLC5A11, solute carrier family 5 member 11, [RH, Score=524, Expect=1e-178]} {Mouse: ENSMUSG00000028544, Slc5a9, solute carrier family 5 (sodium/glucose cotransporter), member 9, [Score=533, Expect=0.0]; ENSMUSG00000030769, Slc5a11, solute carrier family 5 (sodium/glucose cotransporter), member 11, [Score=530, Expect=0.0]; ENSMUSG00000030781, Slc5a2, solute carrier family 5 (sodium/glucose cotransporter), member 2, [Score=512, Expect=2e-174]} {Dmel: FBgn0035293, CG5687, [Score=74.7, Expect=1e-13]} {Celegans: WBGene00014092, ZK822.5, [Score=74.3, Expect=1e-13]} {Smed: dd_Smed_v6_6663_0_1, dd_Smed_v6_6663_0_1, [Score=518, Expect=6e-177]} {RNA1509_21584, RNA1509_2442, RNA1509_51017} {RNA1310_8599.1, RNA1509_21584, RNA1509_2442, RNA1509_51017} {RNA1509_21584, RNA1509_2442, RNA1509_51017, RNA815_2477.1}
34. MligTC455_41002 233 4.84 Mlig455_022813

Neo: -

Age: -

PNPLA2 1.74 0.771 - - 0.969 - - Mlig455_022813 {REF} {Length: 4359} {TRANSSPLICED} {Pfam: Patatin-like phospholipase [PF01734.24, score=37.5]} {Human: ENSG00000177666, PNPLA2, patatin like phospholipase domain containing 2, [RH, Score=206, Expect=8e-59]} {Mouse: ENSMUSG00000025509, Pnpla2, patatin-like phospholipase domain containing 2, [RH, Score=203, Expect=4e-58]} {Dmel: FBgn0036449, bmm, brummer, [RH, Score=247, Expect=5e-74]} {Celegans: WBGene00015484, atgl-1, Patanin-like phospholipase domain-containing protein, [RH, Score=188, Expect=3e-51]} {Smed: dd_Smed_v6_9544_0_1, dd_Smed_v6_9544_0_1, [RH, Score=224, Expect=1e-65]} {RNA1509_22408, RNA1509_31645} {RNA1310_13835, RNA1509_22408, RNA1509_31645} {RNA1509_22408, RNA1509_31645, RNA815_4510}
35. MligTC455_50759 478 9.97 Mlig455_057899

Neo: -

Age: -

1.733 0.762 - - 0.971 - - Mlig455_057899 {REF} {Length: 535} {RNA1509_29040} {RNA1310_42952} {RNA815_48443}
36. MligTC455_34025 813 16.94 Mlig455_009933, Mlig455_035119

Neo: -

Age: Down-Down-Up

Region-enriched R5: 1.687/0.00002
Region-enriched R6: 1.320/0.02488

B3GALT5 1.726 0.774 - - 0.952 - -

Mlig455_009933 {REF} {Length: 4302} {Pfam: Galactosyltransferase [PF01762.23, score=110.1]} {Human: ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [Score=118, Expect=5e-29]} {Mouse: ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [Score=115, Expect=2e-28]} {Dmel: FBgn0000221, brn, brainiac, [Score=140, Expect=2e-37]} {Celegans: WBGene00000270, bre-5, Beta-1,3-galactosyltransferase bre-5, [Score=89.4, Expect=2e-19]} {Smed: dd_Smed_v6_8163_0_1, dd_Smed_v6_8163_0_1, [RH, Score=234, Expect=8e-72]} {RNA1509_33711} {RNA1310_9633.1} {RNA815_14479}

Mlig455_035119 {REF} {Length: 2446} {Pfam: Galactosyltransferase [PF01762.23, score=110.5]} {Human: ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [Score=116, Expect=3e-28]; ENSG00000169255, B3GALNT1, beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group), [Score=112, Expect=1e-26]} {Mouse: ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [Score=114, Expect=5e-28]} {Dmel: FBgn0000221, brn, brainiac, [Score=142, Expect=7e-38]} {Celegans: WBGene00000270, bre-5, Beta-1,3-galactosyltransferase bre-5, [Score=90.5, Expect=8e-20]} {Smed: dd_Smed_v6_8163_0_1, dd_Smed_v6_8163_0_1, [Score=231, Expect=8e-71]} {RNA1509_33711} {RNA1310_9633.2} {RNA815_14479}
37. MligTC455_42518 397 8.27 Mlig455_061703

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.454

Region-enriched R6: 2.767/0.02583

Regeneration-enriched R5: 3.056
Regeneration-enriched R4: 2.829

HES1 1.71 - - - 0.951 0.759 - Mlig455_061703 {REF} {Length: 1173} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=39.6]} {Human: ENSG00000114315, HES1, hes family bHLH transcription factor 1, [Score=58.9, Expect=2e-10]} {Mouse: ENSMUSG00000022528, Hes1, hes family bHLH transcription factor 1, [Score=58.5, Expect=1e-10]} {Dmel: FBgn0010109, dpn, deadpan, [Score=64.3, Expect=1e-12]} {Celegans: WBGene00003008, lin-22, Lin-22, [Score=45.8, Expect=1e-06]} {Smed: dd_Smed_v6_17332_0_1, dd_Smed_v6_17332_0_1, [Score=43.9, Expect=6e-06]} {RNA1310_30690} {RNA815_13906}
38. MligTC455_36696 1081 22.51 Mlig455_029781, Mlig455_029931

Neo: Irradiation

Age: -

Region-specific R5: 3.121

Region-enriched R5: 2.340/0.00000

NOTCH1 1.709 - - - 0.959 0.750 -

Mlig455_029781 {REF} {Length: 5944} {Pfam: EGF-like domain [PF00008.29, score=196.5]; Ankyrin repeats (3 copies) [PF12796.9, score=151.2]; Human growth factor-like EGF [PF12661.9, score=101.4]; Ankyrin repeat [PF00023.32, score=79.2]; Ankyrin repeat [PF13606.8, score=73.4]; Ankyrin repeats (many copies) [PF13857.8, score=70.0]; Ankyrin repeats (many copies) [PF13637.8, score=66.1]; LNR domain [PF00066.19, score=63.4]; EGF-like domain [PF07974.15, score=53.4]; Calcium-binding EGF domain [PF07645.17, score=32.5]; Alliinase EGF-like domain [PF04863.15, score=23.6]; EGF domain [PF12947.9, score=19.7]} {Human: ENSG00000148400, NOTCH1, notch 1, [RH, Score=529, Expect=6e-156]; ENSG00000234876, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000223355, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000235396, NOTCH4, notch 4, [RH, Score=518, Expect=6e-154]; ENSG00000204301, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000232339, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000206312, NOTCH4, notch 4, [RH, Score=516, Expect=3e-153]; ENSG00000074181, NOTCH3, notch 3, [RH, Score=515, Expect=1e-151]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [RH, Score=526, Expect=2e-155]} {Dmel: FBgn0004647, N, Notch, [RH, Score=541, Expect=4e-160]} {Celegans: WBGene00001609, glp-1, [RH, Score=262, Expect=5e-71]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [RH, Score=386, Expect=2e-109]} {RNA1509_4917} {RNA1310_700} {RNA815_15747}

Mlig455_029931 {REF} {Length: 6142} {Pfam: EGF-like domain [PF00008.29, score=185.5]; Ankyrin repeats (3 copies) [PF12796.9, score=151.2]; Human growth factor-like EGF [PF12661.9, score=95.1]; Ankyrin repeat [PF00023.32, score=79.2]; Ankyrin repeat [PF13606.8, score=73.5]; Ankyrin repeats (many copies) [PF13857.8, score=70.1]; Ankyrin repeats (many copies) [PF13637.8, score=66.0]; EGF-like domain [PF07974.15, score=63.3]; LNR domain [PF00066.19, score=62.5]; Calcium-binding EGF domain [PF07645.17, score=32.8]; Alliinase EGF-like domain [PF04863.15, score=23.6]; EGF domain [PF12947.9, score=19.8]} {Human: ENSG00000148400, NOTCH1, notch 1, [RH, Score=527, Expect=2e-155]; ENSG00000234876, NOTCH4, notch 4, [RH, Score=520, Expect=2e-154]; ENSG00000204301, NOTCH4, notch 4, [RH, Score=520, Expect=2e-154]; ENSG00000223355, NOTCH4, notch 4, [RH, Score=520, Expect=3e-154]; ENSG00000232339, NOTCH4, notch 4, [RH, Score=520, Expect=2e-154]; ENSG00000235396, NOTCH4, notch 4, [RH, Score=519, Expect=4e-154]; ENSG00000206312, NOTCH4, notch 4, [RH, Score=516, Expect=3e-153]; ENSG00000074181, NOTCH3, notch 3, [RH, Score=511, Expect=2e-150]} {Mouse: ENSMUSG00000026923, Notch1, notch 1, [RH, Score=546, Expect=5e-162]; ENSMUSG00000038146, Notch3, notch 3, [RH, Score=521, Expect=8e-154]} {Dmel: FBgn0004647, N, Notch, [RH, Score=588, Expect=3e-176]} {Celegans: WBGene00003001, lin-12, [RH, Score=282, Expect=4e-77]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=388, Expect=4e-110]} {RNA1509_4917} {RNA1310_700, RNA1509_4917} {RNA1509_4917, RNA815_15747}
39. MligTC455_29886 979 20.4 Mlig455_029016

Neo: -

Age: logFC(26M/2M)=-0.339

Region-enriched R3: 1.707/0.00111

1.707 0.744 - - 0.963 - - Mlig455_029016 {REF} {Length: 2165} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=364.0]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=121, Expect=1e-30]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=304, Expect=3e-100]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=305, Expect=3e-100]} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1310_23805, RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541, RNA815_9290}
40. MligTC455_46987 185 3.85 Mlig455_026500

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.555

1.697 - - - 0.726 0.971 - Mlig455_026500 {REF} {Length: 1602} {RNA1310_24230.1} {RNA815_12415}
41. MligTC455_19714 956 19.91 Mlig455_002912, Mlig455_002914

Neo: -

Age: Down-Down-Up

RIDA 1.692 - - - 0.971 0.721 -

Mlig455_002912 {REF} {Length: 1773} {TRANSSPLICED} {Pfam: Endoribonuclease L-PSP [PF01042.23, score=99.4]} {Human: ENSG00000132541, RIDA, reactive intermediate imine deaminase A homolog, [Score=117, Expect=5e-34]} {Mouse: ENSMUSG00000022323, Rida, reactive intermediate imine deaminase A homolog, [Score=115, Expect=2e-33]} {Dmel: FBgn0086691, UK114, [Score=81.6, Expect=2e-20]} {Celegans: WBGene00016011, C23G10.2, RutC family protein C23G10.2, [Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1895_0_1, dd_Smed_v6_1895_0_1, [Score=118, Expect=4e-35]} {RNA1509_22089} {RNA1310_28404} {RNA815_23611}

Mlig455_002914 {REF} {Length: 1069} {TRANSSPLICED} {Pfam: Endoribonuclease L-PSP [PF01042.23, score=99.4]} {Human: ENSG00000132541, RIDA, reactive intermediate imine deaminase A homolog, [Score=117, Expect=5e-34]} {Mouse: ENSMUSG00000022323, Rida, reactive intermediate imine deaminase A homolog, [Score=115, Expect=2e-33]} {Dmel: FBgn0086691, UK114, [Score=81.6, Expect=2e-20]} {Celegans: WBGene00016011, C23G10.2, RutC family protein C23G10.2, [Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1895_0_1, dd_Smed_v6_1895_0_1, [Score=118, Expect=4e-35]} {RNA1509_22089} {RNA1310_28404} {RNA815_23611}
42. MligTC455_45421 1113 23.18 Mlig455_061978

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.233/0.00214

1.69 0.736 - - 0.954 - - Mlig455_061978 {REF} {Length: 1540} {Pfam: Sleepless protein [PF17064.7, score=32.3]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.2, Expect=3e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [RH, Score=53.1, Expect=3e-09]} {RNA1509_12407, RNA1509_19531, RNA1509_9020} {RNA1310_25351.3, RNA1509_12407, RNA1509_19531} {RNA1509_12407, RNA1509_19531, RNA815_8070}
43. MligTC455_23732 19718 410.8 Mlig455_003497

Neo: Int S/G2/M

Age: -

YWHAZ 1.665 - - - 0.714 0.951 - Mlig455_003497 {REF} {Length: 2261} {Pfam: 14-3-3 protein [PF00244.22, score=347.7]} {Human: ENSG00000164924, YWHAZ, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, [RH, Score=356, Expect=6e-125]; ENSG00000166913, YWHAB, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta, [RH, Score=355, Expect=7e-125]; ENSG00000134308, YWHAQ, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, [RH, Score=347, Expect=1e-121]; ENSG00000170027, YWHAG, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, [RH, Score=340, Expect=1e-118]} {Mouse: ENSMUSG00000022285, Ywhaz, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, [RH, Score=355, Expect=7e-125]; ENSMUSG00000018326, Ywhab, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, [RH, Score=353, Expect=3e-124]; ENSMUSG00000076432, Ywhaq, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, [RH, Score=345, Expect=4e-121]; ENSMUSG00000051391, Ywhag, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, [RH, Score=340, Expect=8e-119]} {Dmel: FBgn0004907, 14-3-3zeta, [RH, Score=360, Expect=7e-127]} {Celegans: WBGene00001502, ftt-2, 14-3-3-like protein 2, [RH, Score=354, Expect=1e-124]} {Smed: dd_Smed_v6_5419_0_1, dd_Smed_v6_5419_0_1, [RH, Score=366, Expect=3e-129]} {RNA1509_100} {RNA1310_4196.2, RNA1509_100} {RNA1509_100, RNA815_2682.1}
44. MligTC455_16507 120 2.5 Mlig455_062916

Neo: -

Age: -

CTNS 0.987 - - - 0.987 - - Mlig455_062916 {REF} {Length: 2187} {Pfam: PQ loop repeat [PF04193.16, score=98.2]} {Human: ENSG00000040531, CTNS, cystinosin, lysosomal cystine transporter, [Score=252, Expect=4e-79]} {Mouse: ENSMUSG00000005949, Ctns, cystinosis, nephropathic, [Score=246, Expect=2e-77]} {Dmel: FBgn0039045, CG17119, [RH, Score=269, Expect=4e-86]} {Celegans: WBGene00008052, ctns-1, Cystinosin homolog, [RH, Score=228, Expect=2e-70]} {Smed: dd_Smed_v6_4571_0_1, dd_Smed_v6_4571_0_1, [RH, Score=271, Expect=8e-88]} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1310_18560, RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307, RNA815_7181}
45. MligTC455_04428 655 13.66 Mlig455_071088

Neo: -

Age: -

Region-enriched R4: 3.160/0.00859

0.978 - - - 0.978 - - Mlig455_071088 {REF} {Length: 272} {NoTransDecoderORF} {RNA1509_284} {RNA1310_24413} {RNA815_6153}
46. MligTC455_51435 176 3.67 Mlig455_024682

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.635/0.03730

RNF165 0.971 - - - - 0.971 - Mlig455_024682 {REF} {Length: 2972} {TRANSSPLICED} {Pfam: Ring finger domain [PF13639.8, score=37.7]; zinc-RING finger domain [PF14634.8, score=23.4]; RING-H2 zinc finger domain [PF12678.9, score=22.4]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=19.7]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=18.4]} {Human: ENSG00000141622, RNF165, ring finger protein 165, [Score=52.8, Expect=1e-07]; ENSG00000157450, RNF111, ring finger protein 111, [Score=52.0, Expect=2e-06]; ENSG00000099999, RNF215, ring finger protein 215, [Score=50.4, Expect=4e-06]} {Mouse: ENSMUSG00000025427, Rnf165, ring finger protein 165, [Score=52.8, Expect=7e-08]; ENSMUSG00000032217, Rnf111, ring finger 111, [Score=51.6, Expect=2e-06]; ENSMUSG00000003581, Rnf215, ring finger protein 215, [Score=50.8, Expect=2e-06]} {Dmel: FBgn0037944, CG6923, [Score=50.1, Expect=4e-06]} {Celegans: WBGene00015194, B0432.13, [RH, Score=72.4, Expect=2e-13]} {Smed: dd_Smed_v6_45208_0_1, dd_Smed_v6_45208_0_1, [RH, Score=56.2, Expect=4e-09]} {RNA1509_38484, RNA1509_41878} {RNA1310_16843, RNA1509_38484, RNA1509_41878} {RNA1509_38484, RNA1509_41878, RNA815_15976}
47. MligTC455_15552 291 6.06 Mlig455_051007

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.527

0.97 - - - - 0.970 - Mlig455_051007 {REF} {Length: 2931} {RNA1509_27433} {RNA1310_3013} {RNA815_768.2}
48. MligTC455_33504 1496 31.16 Mlig455_021195

Neo: -

Age: logFC(26M/2M)=0.203

XAB2 0.967 - - - - - 0.967 Mlig455_021195 {REF} {Length: 3351} {TRANSSPLICED} {Pfam: Ribosomal protein S19e [PF01090.21, score=160.6]; Tetratricopeptide repeat [PF13428.8, score=57.8]; Suppressor of forked protein (Suf) [PF05843.16, score=39.3]; Tetratricopeptide repeat [PF14559.8, score=38.4]; Tetratricopeptide repeat [PF13429.8, score=36.8]; Tetratricopeptide repeat [PF07719.19, score=31.9]; Tetratricopeptide repeat [PF13424.8, score=28.2]; NRDE-2, necessary for RNA interference [PF08424.12, score=24.4]; Mad3/BUB1 homology region 1 [PF08311.14, score=20.5]} {Human: ENSG00000076924, XAB2, XPA binding protein 2, [RH, Score=872, Expect=0.0]} {Mouse: ENSMUSG00000019470, Xab2, XPA binding protein 2, [RH, Score=873, Expect=0.0]} {Dmel: FBgn0033859, fand, fandango, [RH, Score=862, Expect=0.0]} {Celegans: WBGene00016837, syf-1, [RH, Score=755, Expect=0.0]} {Smed: dd_Smed_v6_6473_0_1, dd_Smed_v6_6473_0_1, [RH, Score=717, Expect=0.0]} {RNA1509_19732, RNA1509_5006} {RNA1310_2111.1, RNA1509_19732} {RNA1509_19732, RNA815_1651.1}
49. MligTC455_17284 28 0.58 Mlig455_021795

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.028

0.965 - - - 0.965 - - Mlig455_021795 {REF} {Length: 3140} {RNA1509_16895} {RNA1310_22424.1} {RNA815_3739}
50. MligTC455_22000 646 13.45 Mlig455_042166

Neo: -

Age: -

Region-specific R5: 4.983

Region-enriched R5: 4.561/0.00000
Region-enriched R6: 2.361/0.01711

Regeneration-upregulated R4: 2.507

Regeneration-enriched R4: 2.507

SLC47A1 0.965 - - - 0.965 - - Mlig455_042166 {REF} {Length: 2839} {Pfam: MatE [PF01554.20, score=185.2]; Polysaccharide biosynthesis C-terminal domain [PF14667.8, score=29.4]} {Human: ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=300, Expect=6e-93]} {Mouse: ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=309, Expect=6e-97]} {Smed: dd_Smed_v6_7241_0_1, dd_Smed_v6_7241_0_1, [Score=410, Expect=6e-135]} {RNA1509_32271, RNA1509_50596} {RNA1310_8561.1, RNA1509_32271, RNA1509_50596} {RNA1509_32271, RNA1509_50596, RNA815_2534.1}
51. MligTC455_37964 3298 68.72 Mlig455_056045

Neo: -

Age: logFC(26M/2M)=1.465

HSD17B4 0.963 - - - 0.963 - - Mlig455_056045 {REF} {Length: 2688} {Pfam: short chain dehydrogenase [PF00106.27, score=134.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=112.0]; MaoC like domain [PF01575.21, score=101.4]; SCP-2 sterol transfer family [PF02036.19, score=70.6]; KR domain [PF08659.12, score=53.8]} {Human: ENSG00000133835, HSD17B4, hydroxysteroid 17-beta dehydrogenase 4, [RH, Score=810, Expect=0.0]} {Mouse: ENSMUSG00000024507, Hsd17b4, hydroxysteroid (17-beta) dehydrogenase 4, [RH, Score=781, Expect=0.0]} {Dmel: FBgn0030731, Mfe2, peroxisomal Multifunctional enzyme type 2, [RH, Score=595, Expect=0.0]} {Celegans: WBGene00000991, dhs-28, DeHydrogenases, Short chain, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_5867_0_1, dd_Smed_v6_5867_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_9012} {RNA1310_590.1} {RNA815_2204}
52. MligTC455_14821 305 6.35 Mlig455_018773

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.196/0.03323
Region-enriched R5: 1.788/0.02997

PANK1 0.962 - - - 0.962 - - Mlig455_018773 {REF} {Length: 2765} {Pfam: Fumble [PF03630.16, score=101.1]} {Human: ENSG00000152782, PANK1, pantothenate kinase 1, [Score=55.5, Expect=6e-08]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=79.7, Expect=9e-16]} {Dmel: FBgn0011205, fbl, fumble, [Score=56.2, Expect=2e-08]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=73.2, Expect=5e-14]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=182, Expect=4e-54]} {RNA1509_12016} {RNA1310_16423} {RNA815_7574.1}
53. MligTC455_17727 4189 87.27 Mlig455_057688, Mlig455_059984

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.941

Region-enriched R6: 2.088/0.01181
Region-enriched R5: 1.460/0.04298

0.96 - - - 0.960 - -

Mlig455_057688 {REF} {Length: 980} {RNA1509_889} {RNA1310_48596} {RNA815_26649}

Mlig455_059984 {REF} {Length: 988} {RNA1509_14511, RNA1509_20501, RNA1509_889} {RNA1310_48596, RNA1509_14511, RNA1509_20501, RNA1509_889} {RNA1509_14511, RNA1509_20501, RNA1509_889, RNA815_26649}
54. MligTC455_25272 586 12.2 Mlig455_035775, Mlig455_035886

Neo: -

Age: -

XPO7 0.958 - - - - 0.958 -

Mlig455_035775 {REF} {Length: 5916} {Pfam: Importin-beta N-terminal domain [PF03810.21, score=22.1]} {Human: ENSG00000130227, XPO7, exportin 7, [RH, Score=1231, Expect=0.0]} {Mouse: ENSMUSG00000022100, Xpo7, exportin 7, [RH, Score=1228, Expect=0.0]} {Dmel: FBgn0053180, Ranbp16, [RH, Score=1074, Expect=0.0]} {Celegans: WBGene00007952, C35A5.8, [RH, Score=783, Expect=0.0]} {Smed: dd_Smed_v6_5566_0_1, dd_Smed_v6_5566_0_1, [RH, Score=729, Expect=0.0]} {RNA1509_6691} {RNA1310_1345.1} {RNA815_775.1}

Mlig455_035886 {REF} {Length: 5703} {TRANSSPLICED} {Pfam: Importin-beta N-terminal domain [PF03810.21, score=22.1]} {Human: ENSG00000130227, XPO7, exportin 7, [RH, Score=1231, Expect=0.0]} {Mouse: ENSMUSG00000022100, Xpo7, exportin 7, [RH, Score=1228, Expect=0.0]} {Dmel: FBgn0053180, Ranbp16, [RH, Score=1074, Expect=0.0]} {Celegans: WBGene00007952, C35A5.8, [RH, Score=783, Expect=0.0]} {Smed: dd_Smed_v6_5566_0_1, dd_Smed_v6_5566_0_1, [RH, Score=729, Expect=0.0]} {RNA1509_45528, RNA1509_48027, RNA1509_6691} {RNA1310_1345.1, RNA1509_45528, RNA1509_48027} {RNA1509_45528, RNA1509_48027, RNA815_775.1}
55. MligTC455_41507 683 14.22 Mlig455_029753, Mlig455_029849

Neo: -

Age: -

Region-enriched R4: 2.180/0.02027
Region-enriched R5: 1.936/0.00260

0.958 - - - 0.958 - -

Mlig455_029753 {REF} {Length: 2787} {TRANSSPLICED} {RNA1509_43940} {RNA1310_30266, RNA1509_43940} {RNA1509_43940, RNA815_27401}

Mlig455_029849 {REF} {Length: 3264} {TRANSSPLICED} {RNA1509_43940} {RNA1310_30266} {RNA815_27401}
56. MligTC455_46995 445 9.27 Mlig455_039509

Neo: -

Age: logFC(26M/2M)=0.375

USB1 0.957 - - - 0.957 - - Mlig455_039509 {REF} {Length: 2185} {TRANSSPLICED} {Pfam: Uncharacterised conserved protein [PF09749.11, score=128.8]} {Human: ENSG00000103005, USB1, U6 snRNA biogenesis phosphodiesterase 1, [RH, Score=115, Expect=2e-30]} {Mouse: ENSMUSG00000031792, Usb1, U6 snRNA biogenesis 1, [RH, Score=120, Expect=2e-32]} {Dmel: FBgn0037713, CG16790, [RH, Score=120, Expect=1e-32]} {RNA1509_23851} {RNA1310_12885.1} {RNA815_5897}
57. MligTC455_46510 48 0.99 Mlig455_023192

Neo: -

Age: -

ANGPTL3 0.956 - - - 0.956 - - Mlig455_023192 {REF} {Length: 2070} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=60.4]; PAN domain [PF14295.8, score=24.4]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=58.2, Expect=1e-08]} {Mouse: ENSMUSG00000028553, Angptl3, angiopoietin-like 3, [Score=48.9, Expect=7e-06]; ENSMUSG00000002289, Angptl4, angiopoietin-like 4, [Score=48.9, Expect=6e-06]; ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=48.5, Expect=1e-05]} {Dmel: FBgn0031804, CG9500, [Score=70.5, Expect=2e-13]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=50.8, Expect=8e-07]} {RNA1509_53291} {RNA1310_30694.1} {RNA815_9881}
58. MligTC455_50450 289 6.03 Mlig455_025789

Neo: -

Age: -

Region-enriched R4: 2.436/0.00472

GRHPR 0.956 - - - 0.956 - - Mlig455_025789 {REF} {Length: 1745} {TRANSSPLICED} {Pfam: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=175.7]; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [PF00389.32, score=56.3]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.6]} {Human: ENSG00000137106, GRHPR, glyoxylate and hydroxypyruvate reductase, [Score=168, Expect=4e-49]} {Mouse: ENSMUSG00000035637, Grhpr, glyoxylate reductase/hydroxypyruvate reductase, [Score=169, Expect=9e-50]} {Dmel: FBgn0032889, CG9331, [Score=138, Expect=4e-38]} {Celegans: WBGene00007836, C31C9.2, [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_20441_0_1, dd_Smed_v6_20441_0_1, [RH, Score=157, Expect=5e-47]} {RNA1509_9527} {RNA1310_17599} {RNA815_26280}
59. MligTC455_50451 900 18.74 Mlig455_064364, Mlig455_064388

Neo: -

Age: Up-Down-Down

Region-enriched R4: 1.662/0.00486

GRHPR 0.955 - - - 0.955 - -

Mlig455_064364 {REF} {Length: 1741} {TRANSSPLICED} {Pfam: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=175.7]; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [PF00389.32, score=56.3]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.6]} {Human: ENSG00000137106, GRHPR, glyoxylate and hydroxypyruvate reductase, [Score=168, Expect=4e-49]} {Mouse: ENSMUSG00000035637, Grhpr, glyoxylate reductase/hydroxypyruvate reductase, [Score=169, Expect=9e-50]} {Dmel: FBgn0032889, CG9331, [Score=138, Expect=4e-38]} {Celegans: WBGene00007836, C31C9.2, [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_20441_0_1, dd_Smed_v6_20441_0_1, [RH, Score=157, Expect=5e-47]} {RNA1509_9527} {RNA1310_17599} {RNA815_26280}

Mlig455_064388 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=175.7]; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [PF00389.32, score=56.3]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.6]} {Human: ENSG00000137106, GRHPR, glyoxylate and hydroxypyruvate reductase, [Score=168, Expect=4e-49]} {Mouse: ENSMUSG00000035637, Grhpr, glyoxylate reductase/hydroxypyruvate reductase, [Score=169, Expect=9e-50]} {Dmel: FBgn0032889, CG9331, [Score=138, Expect=4e-38]} {Celegans: WBGene00007836, C31C9.2, [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_20441_0_1, dd_Smed_v6_20441_0_1, [RH, Score=157, Expect=5e-47]} {RNA1509_35388, RNA1509_9527} {RNA1310_17599, RNA1509_35388, RNA1509_9527} {RNA1509_35388, RNA1509_9527, RNA815_26280}
60. MligTC455_50788 55 1.14 Mlig455_001945

Neo: -

Age: Down-Up-Up

Region-enriched R4: 4.857/0.00120
Region-enriched R5: 3.283/0.00685

GATA6 0.955 - - - 0.955 - - Mlig455_001945 {REF} {Length: 1855} {tRNA: Val(CAC),pseudo, score=26.6} {Pfam: GATA zinc finger [PF00320.29, score=52.2]; TFIIB zinc-binding [PF08271.14, score=20.7]} {Human: ENSG00000141448, GATA6, GATA binding protein 6, [Score=87.8, Expect=1e-18]; ENSG00000136574, GATA4, GATA binding protein 4, [Score=87.0, Expect=2e-18]; ENSG00000285109, GATA4, GATA binding protein 4, [Score=87.0, Expect=2e-18]} {Mouse: ENSMUSG00000005836, Gata6, GATA binding protein 6, [Score=87.0, Expect=2e-18]; ENSMUSG00000021944, Gata4, GATA binding protein 4, [Score=85.5, Expect=4e-18]} {Dmel: FBgn0032223, GATAd, [RH, Score=87.0, Expect=1e-18]} {Celegans: WBGene00001249, elt-1, Transcription factor elt-1, [Score=83.2, Expect=1e-17]} {Smed: dd_Smed_v6_4075_0_1, dd_Smed_v6_4075_0_1, [Score=80.5, Expect=9e-17]} {RNA1509_47157} {RNA1310_45834} {RNA815_33962}
61. MligTC455_36954 2263 47.15 Mlig455_041278

Neo: -

Age: logFC(26M/2M)=-0.220

Region-enriched R3: 1.232/0.02876

MARC1 0.954 - - - 0.954 - - Mlig455_041278 {REF} {Length: 2109} {Pfam: MOSC N-terminal beta barrel domain [PF03476.18, score=77.0]; MOSC domain [PF03473.19, score=67.6]} {Human: ENSG00000186205, MARC1, mitochondrial amidoxime reducing component 1, [RH, Score=114, Expect=1e-28]} {Mouse: ENSMUSG00000026621, Marc1, mitochondrial amidoxime reducing component 1, [RH, Score=118, Expect=3e-30]; ENSMUSG00000073481, Marc2, mitochondrial amidoxime reducing component 2, [RH, Score=116, Expect=2e-29]} {Dmel: FBgn0033451, CG1665, [RH, Score=81.6, Expect=3e-17]} {Celegans: WBGene00018758, F53E10.1, [RH, Score=98.2, Expect=4e-23]} {Smed: dd_Smed_v6_7493_0_1, dd_Smed_v6_7493_0_1, [Score=63.2, Expect=3e-11]} {RNA1509_12139, RNA1509_16934, RNA1509_25829, RNA1509_27068, RNA1509_4542} {RNA1310_14706.1, RNA1509_12139, RNA1509_16934, RNA1509_25829, RNA1509_27068, RNA1509_4542} {RNA1509_12139, RNA1509_16934, RNA1509_25829, RNA1509_27068, RNA1509_4542, RNA815_10847}
62. MligTC455_53407 49 1.02 Mlig455_051620

Neo: -

Age: -

VPS26C 0.952 - - - 0.952 - - Mlig455_051620 {REF} {Length: 2288} {TRANSSPLICED} {Pfam: Vacuolar protein sorting-associated protein 26 [PF03643.17, score=172.5]} {Human: ENSG00000157538, VPS26C, VPS26 endosomal protein sorting factor C, [RH, Score=376, Expect=2e-131]} {Mouse: ENSMUSG00000022898, Vps26c, VPS26 endosomal protein sorting factor C, [RH, Score=370, Expect=2e-129]} {Dmel: FBgn0037017, CG4074, [RH, Score=273, Expect=2e-91]} {Smed: dd_Smed_v6_3520_0_1, dd_Smed_v6_3520_0_1, [RH, Score=305, Expect=5e-104]} {RNA1509_28631} {RNA1310_29463} {RNA815_13522}
63. MligTC455_17728 1061 22.09 Mlig455_057691

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-4.029

Region-enriched R6: 1.981/0.02890

0.951 - - - 0.951 - - Mlig455_057691 {REF} {Length: 717} {RNA1509_20501} {RNA1310_48596} {RNA815_26649}
64. MligTC455_42438 2020 42.09 Mlig455_055199, Mlig455_055244

Neo: -

Age: -

Region-enriched R3: 2.265/0.00232

0.951 - - - 0.951 - -

Mlig455_055199 {REF} {Length: 6274} {Pfam: Pyruvate phosphate dikinase, AMP/ATP-binding domain [PF01326.21, score=226.3]; PEP-utilising enzyme, mobile domain [PF00391.25, score=75.8]} {Dmel: FBgn0040342, CG3706, [RH, Score=132, Expect=4e-32]} {Celegans: WBGene00011893, T21C9.6, [RH, Score=307, Expect=3e-86]} {Smed: dd_Smed_v6_2604_0_1, dd_Smed_v6_2604_0_1, [RH, Score=855, Expect=0.0]} {RNA1509_1405, RNA1509_6581} {RNA1310_1331, RNA1509_6581} {RNA1509_6581, RNA815_563}

Mlig455_055244 {REF} {Length: 5074} {Pfam: Pyruvate phosphate dikinase, AMP/ATP-binding domain [PF01326.21, score=202.1]} {Dmel: FBgn0040342, CG3706, [RH, Score=132, Expect=8e-33]} {Celegans: WBGene00011893, T21C9.6, [Score=155, Expect=7e-39]} {Smed: dd_Smed_v6_2604_0_1, dd_Smed_v6_2604_0_1, [Score=466, Expect=1e-147]} {RNA1509_1405} {RNA1310_1331} {RNA815_563}
65. MligTC455_11865 160 3.33 Mlig455_037642, Mlig455_069907

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.621

0.95 - - - - 0.950 -

Mlig455_037642 {REF} {Length: 3499} {Pfam: Glycine rich protein [PF12810.9, score=31.7]} {Smed: dd_Smed_v6_12148_0_3, dd_Smed_v6_12148_0_3, [Score=67.4, Expect=2e-12]} {RNA1310_19265.2} {RNA815_13143}

Mlig455_069907 {REF} {Length: 4084} {RNA1310_19265.2} {RNA815_13143}
66. MligTC455_15563 2750 57.29 Mlig455_050862

Neo: Neoblast

Age: Down-Up-Up, logFC(26M/2M)=0.404

CSTF2 0.95 - - - - 0.950 - Mlig455_050862 {REF} {Length: 1346} {TRANSSPLICED} {Pfam: Hinge domain of cleavage stimulation factor subunit 2 [PF14327.8, score=101.8]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=77.0]; Transcription termination and cleavage factor C-terminal [PF14304.8, score=68.6]} {Human: ENSG00000101811, CSTF2, cleavage stimulation factor subunit 2, [RH, Score=263, Expect=5e-82]; ENSG00000177613, CSTF2T, cleavage stimulation factor subunit 2 tau variant, [RH, Score=256, Expect=2e-79]} {Mouse: ENSMUSG00000031256, Cstf2, cleavage stimulation factor, 3' pre-RNA subunit 2, [RH, Score=263, Expect=1e-82]; ENSMUSG00000053536, Cstf2t, cleavage stimulation factor, 3' pre-RNA subunit 2, tau, [RH, Score=255, Expect=4e-79]} {Dmel: FBgn0027841, CstF64, Cleavage stimulation factor 64 kD subunit, [RH, Score=235, Expect=7e-74]} {Celegans: WBGene00000774, cpf-2, Cleavage and Polyadenylation Factor, [RH, Score=207, Expect=5e-64]} {Smed: dd_Smed_v6_3081_0_1, dd_Smed_v6_3081_0_1, [RH, Score=322, Expect=2e-108]} {RNA1509_22227, RNA1509_50706, RNA1509_53963} {RNA1310_25296, RNA1509_22227, RNA1509_50706, RNA1509_53963} {RNA1509_22227, RNA1509_50706, RNA1509_53963, RNA815_16722}

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