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Results for MligTC455_18597

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_18597 2002 41.70 Mlig455_008723, Mlig455_063593

Neo: -

Age: -

Region-enriched R5: 1.210/0.02582

 AGPS

Mlig455_008723 {REF} {Length: 3049} {TRANSSPLICED} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=183.8]; FAD binding domain [PF01565.25, score=116.9]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [RH, Score=770, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [RH, Score=771, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [RH, Score=669, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [RH, Score=702, Expect=0.0]} {RNA1509_6531} {RNA1310_6470.2, RNA1509_6531} {RNA1509_6531, RNA815_2634}

Mlig455_063593 {REF} {Length: 3191} {TRANSSPLICED} {Pfam: FAD binding domain [PF01565.25, score=116.1]; FAD linked oxidases, C-terminal domain [PF02913.21, score=111.2]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [Score=683, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [Score=685, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [Score=566, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [Score=583, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [Score=620, Expect=0.0]} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA1509_6531} {RNA1310_6470.2, RNA1509_28418, RNA1509_50386, RNA1509_53669} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA815_2634}

Cumulative graph for MligTC455_18597

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.37 5.618 0.14802 0.76159
RegionR2 -0.233 5.618 0.67542 1.00000
RegionR3 0.756 5.618 0.08386 0.51271
RegionR4 0.525 5.618 0.28365 0.59243
RegionR5 1.21 5.618 0.00338 0.02582
RegionR6 0.401 5.618 0.37775 0.95800
RegionR7 -1.105 5.618 0.04734 0.41836
RegionR8 -0.184 5.618 0.73480 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.418 5.618 0.05083 0.69964
RegenerationR2 -0.51 5.618 0.36953 0.79538
RegenerationR3 -0.035 5.618 0.95134 1.00000
RegenerationR4 0.619 5.618 0.28551 0.73050
RegenerationR5 0.39 5.618 0.48214 0.84731
RegenerationR6 0.77 5.618 0.17608 0.50935
RegenerationBL 0.351 5.618 0.50512 0.86876
RegenerationTP -0.225 5.618 0.71536 1.00000


Genes with expression patterns similar to MligTC455_18597

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_18597 2002 41.7 Mlig455_008723, Mlig455_063593

Neo: -

Age: -

Region-enriched R5: 1.210/0.02582

 AGPS 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_008723 {REF} {Length: 3049} {TRANSSPLICED} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=183.8]; FAD binding domain [PF01565.25, score=116.9]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [RH, Score=770, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [RH, Score=771, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [RH, Score=669, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [RH, Score=702, Expect=0.0]} {RNA1509_6531} {RNA1310_6470.2, RNA1509_6531} {RNA1509_6531, RNA815_2634}

Mlig455_063593 {REF} {Length: 3191} {TRANSSPLICED} {Pfam: FAD binding domain [PF01565.25, score=116.1]; FAD linked oxidases, C-terminal domain [PF02913.21, score=111.2]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [Score=683, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [Score=685, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [Score=566, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [Score=583, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [Score=620, Expect=0.0]} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA1509_6531} {RNA1310_6470.2, RNA1509_28418, RNA1509_50386, RNA1509_53669} {RNA1509_28418, RNA1509_50386, RNA1509_53669, RNA815_2634}
2. MligTC455_34755 1776 36.99 Mlig455_050399

Neo: -

Age: -

 PFKM 3.392 - - 0.737 0.958 0.878 0.819 Mlig455_050399 {REF} {Length: 3919} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=609.5]} {Human: ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=830, Expect=0.0]} {Mouse: ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=826, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=805, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [Score=834, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=810, Expect=0.0]} {Smed: dd_Smed_v6_3613_0_1, dd_Smed_v6_3613_0_1, [Score=864, Expect=0.0]} {RNA1509_45109, RNA1509_4935} {RNA1310_2251.3, RNA1509_45109} {RNA1509_45109, RNA815_2567}
3. MligTC455_19521 1093 22.77 Mlig455_056856

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.248

Region-enriched R4: 1.796/0.00007

 3.32 - 0.737 - 0.864 0.761 0.958 Mlig455_056856 {REF} {Length: 2007} {Pfam: Phosphatidyl serine synthase [PF03034.17, score=22.0]} {Mouse: ENSMUSG00000025495, Ptdss2, phosphatidylserine synthase 2, [Score=55.8, Expect=3e-10]} {Smed: dd_Smed_v6_7678_0_1, dd_Smed_v6_7678_0_1, [Score=84.3, Expect=1e-20]} {RNA1509_25799} {RNA1310_5581} {RNA815_3642.1}
4. MligTC455_50451 900 18.74 Mlig455_064364, Mlig455_064388

Neo: -

Age: Up-Down-Down

Region-enriched R4: 1.662/0.00486

 GRHPR 3.28 0.701 - - 0.951 0.750 0.878

Mlig455_064364 {REF} {Length: 1741} {TRANSSPLICED} {Pfam: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=175.7]; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [PF00389.32, score=56.3]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.6]} {Human: ENSG00000137106, GRHPR, glyoxylate and hydroxypyruvate reductase, [Score=168, Expect=4e-49]} {Mouse: ENSMUSG00000035637, Grhpr, glyoxylate reductase/hydroxypyruvate reductase, [Score=169, Expect=9e-50]} {Dmel: FBgn0032889, CG9331, [Score=138, Expect=4e-38]} {Celegans: WBGene00007836, C31C9.2, [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_20441_0_1, dd_Smed_v6_20441_0_1, [RH, Score=157, Expect=5e-47]} {RNA1509_9527} {RNA1310_17599} {RNA815_26280}

Mlig455_064388 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=175.7]; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [PF00389.32, score=56.3]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.6]} {Human: ENSG00000137106, GRHPR, glyoxylate and hydroxypyruvate reductase, [Score=168, Expect=4e-49]} {Mouse: ENSMUSG00000035637, Grhpr, glyoxylate reductase/hydroxypyruvate reductase, [Score=169, Expect=9e-50]} {Dmel: FBgn0032889, CG9331, [Score=138, Expect=4e-38]} {Celegans: WBGene00007836, C31C9.2, [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_20441_0_1, dd_Smed_v6_20441_0_1, [RH, Score=157, Expect=5e-47]} {RNA1509_35388, RNA1509_9527} {RNA1310_17599, RNA1509_35388, RNA1509_9527} {RNA1509_35388, RNA1509_9527, RNA815_26280}
5. MligTC455_44645 563 11.72 Mlig455_070220

Neo: -

Age: -

 SLC28A1 3.272 0.807 - - 0.956 0.726 0.783 Mlig455_070220 {REF} {Length: 2524} {Pfam: Na+ dependent nucleoside transporter C-terminus [PF07662.15, score=236.4]; Na+ dependent nucleoside transporter N-terminus [PF01773.22, score=73.8]; Nucleoside recognition [PF07670.16, score=23.7]} {Human: ENSG00000156222, SLC28A1, solute carrier family 28 member 1, [RH, Score=377, Expect=7e-123]; ENSG00000137860, SLC28A2, solute carrier family 28 member 2, [RH, Score=369, Expect=3e-119]} {Mouse: ENSMUSG00000027219, Slc28a2, solute carrier family 28 (sodium-coupled nucleoside transporter), member 2, [RH, Score=385, Expect=6e-126]; ENSMUSG00000025726, Slc28a1, solute carrier family 28 (sodium-coupled nucleoside transporter), member 1, [RH, Score=377, Expect=1e-122]} {Dmel: FBgn0025709, CNT2, Concentrative nucleoside transporter 2, [Score=300, Expect=5e-94]} {Celegans: WBGene00017868, slc-28.2, Sodium/nucleoside cotransporter, [RH, Score=240, Expect=2e-71]} {Smed: dd_Smed_v6_3508_0_1, dd_Smed_v6_3508_0_1, [Score=456, Expect=3e-154]} {RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1310_7732, RNA1509_20711, RNA1509_21619, RNA1509_48971} {RNA1509_20711, RNA1509_21619, RNA1509_48971, RNA815_2578}
6. MligTC455_48283 909 18.94 Mlig455_026664

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.206

Region-enriched R4: 1.636/0.00109

 VMP1 2.747 - - - 0.957 0.844 0.946 Mlig455_026664 {REF} {Length: 4250} {Pfam: SAP domain [PF02037.29, score=41.2]; SNARE associated Golgi protein [PF09335.13, score=32.6]; SAP domain-containing new25 [PF18953.2, score=19.7]} {Human: ENSG00000062716, VMP1, vacuole membrane protein 1, [RH, Score=381, Expect=4e-128]} {Mouse: ENSMUSG00000018171, Vmp1, vacuole membrane protein 1, [RH, Score=388, Expect=7e-131]} {Dmel: FBgn0052675, Tango5, Transport and Golgi organization 5, [RH, Score=378, Expect=2e-125]} {Celegans: WBGene00012559, epg-3, Ectopic P granules protein 3, [RH, Score=371, Expect=6e-124]} {Smed: dd_Smed_v6_1156_0_1, dd_Smed_v6_1156_0_1, [RH, Score=281, Expect=6e-90]} {RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125} {RNA1310_6077, RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125} {RNA1509_21487, RNA1509_24070, RNA1509_40428, RNA1509_53125, RNA815_1510}
7. MligTC455_19715 467 9.74 Mlig455_002931

Neo: -

Age: logFC(26M/2M)=-0.732

Region-enriched R4: 1.523/0.02873

 RIDA 2.687 - - - 0.965 0.843 0.879 Mlig455_002931 {REF} {Length: 1022} {TRANSSPLICED} {Pfam: Endoribonuclease L-PSP [PF01042.23, score=99.4]} {Human: ENSG00000132541, RIDA, reactive intermediate imine deaminase A homolog, [Score=117, Expect=5e-34]} {Mouse: ENSMUSG00000022323, Rida, reactive intermediate imine deaminase A homolog, [Score=115, Expect=2e-33]} {Dmel: FBgn0086691, UK114, [Score=81.6, Expect=2e-20]} {Celegans: WBGene00016011, C23G10.2, RutC family protein C23G10.2, [Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1895_0_1, dd_Smed_v6_1895_0_1, [Score=118, Expect=4e-35]} {RNA1509_16898, RNA1509_22089} {RNA1310_27243, RNA1509_16898, RNA1509_22089} {RNA1509_16898, RNA1509_22089, RNA815_23611}
8. MligTC455_43797 2681 55.85 Mlig455_051343

Neo: -

Age: logFC(26M/2M)=0.181

Region-enriched R5: 1.067/0.00046

 SHMT2 2.672 - - - 0.970 0.839 0.863 Mlig455_051343 {REF} {Length: 1803} {TRANSSPLICED} {Pfam: Serine hydroxymethyltransferase [PF00464.21, score=614.7]} {Human: ENSG00000182199, SHMT2, serine hydroxymethyltransferase 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000025403, Shmt2, serine hydroxymethyltransferase 2 (mitochondrial), [RH, Score=657, Expect=0.0]} {Dmel: FBgn0029823, Shmt, Serine hydroxymethyl transferase, [RH, Score=594, Expect=0.0]} {Celegans: WBGene00003214, mel-32, Serine hydroxymethyltransferase, [RH, Score=567, Expect=0.0]} {Smed: dd_Smed_v6_7793_0_1, dd_Smed_v6_7793_0_1, [RH, Score=638, Expect=0.0]} {RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642} {RNA1310_15013, RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642} {RNA1509_15664, RNA1509_23750, RNA1509_31482, RNA1509_4642, RNA815_5372}
9. MligTC455_40739 1244 25.91 Mlig455_005845

Neo: -

Age: logFC(26M/2M)=-0.318

Region-enriched R4: 2.303/0.00001
Region-enriched R5: 1.932/0.00000
Region-enriched R3: 1.599/0.00189
Region-enriched R6: 1.539/0.00828

Regeneration-upregulated BL: 2.384

Regeneration-enriched BL: 2.384

 HAAO 2.668 - - - 0.885 0.958 0.825 Mlig455_005845 {REF} {Length: 1402} {TRANSSPLICED} {Pfam: 3-hydroxyanthranilic acid dioxygenase [PF06052.14, score=168.6]} {Human: ENSG00000162882, HAAO, 3-hydroxyanthranilate 3,4-dioxygenase, [RH, Score=204, Expect=6e-64]} {Mouse: ENSMUSG00000000673, Haao, 3-hydroxyanthranilate 3,4-dioxygenase, [RH, Score=216, Expect=1e-68]} {Celegans: WBGene00010595, haao-1, 3-hydroxyanthranilate 3,4-dioxygenase, [RH, Score=160, Expect=5e-47]} {Smed: dd_Smed_v6_3032_0_1, dd_Smed_v6_3032_0_1, [RH, Score=140, Expect=1e-39]} {RNA1509_15849, RNA1509_27109} {RNA1310_23508, RNA1509_15849, RNA1509_27109} {RNA1509_15849, RNA1509_27109, RNA815_8418}
10. MligTC455_45275 384 8 Mlig455_037525

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.804

Region-enriched R4: 2.211/0.00561

 2.628 - - - 0.958 0.844 0.826 Mlig455_037525 {REF} {Length: 1617} {Pfam: HYD1 signature containing ADP-ribosyltransferase [PF15633.8, score=44.2]} {RNA1509_38410, RNA1509_7973} {RNA1310_28627, RNA1509_38410, RNA1509_7973} {RNA1509_38410, RNA1509_7973, RNA815_9390.1}
11. MligTC455_27832 1170 24.38 Mlig455_048328

Neo: Irradiation

Age: -

Region-enriched R5: 1.315/0.00946

 OPLAH 2.615 0.874 - - 0.958 0.783 - Mlig455_048328 {REF} {Length: 9221} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=675.2]; Hydantoinase/oxoprolinase [PF01968.20, score=305.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=151.6]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=26.4]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=795, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=777, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=756, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=762, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=845, Expect=0.0]} {RNA1509_2948} {RNA1310_4544} {RNA815_468}
12. MligTC455_27831 1160 24.16 Mlig455_048304

Neo: -

Age: -

Region-enriched R5: 1.322/0.01164

 OPLAH 2.612 0.874 - - 0.956 0.782 - Mlig455_048304 {REF} {Length: 1597} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=677.6]; Hydantoinase/oxoprolinase [PF01968.20, score=348.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=172.3]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.3]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=76.9]; Integrase zinc binding domain [PF17921.3, score=68.9]; Aspartyl protease [PF13650.8, score=38.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=35.2]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=25.9]; Retroviral aspartyl protease [PF00077.22, score=24.3]; Aspartyl protease [PF09668.12, score=23.4]; Putative peptidase (DUF1758) [PF05585.14, score=21.1]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=800, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=779, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=757, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=763, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=847, Expect=0.0]} {RNA1509_2948} {RNA1310_1508.2} {RNA815_468}
13. MligTC455_43156 30659 638.72 Mlig455_013212, Mlig455_013235, Mlig455_013307

Neo: -

Age: logFC(26M/2M)=-0.210

Region-enriched R6: 1.505/0.00540
Region-enriched R5: 1.426/0.00133
Region-enriched R4: 1.190/0.03651

 2.598 - - - 0.974 0.863 0.761

Mlig455_013212 {REF} {Length: 1340} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=78.1]; Methyltransferase domain [PF13649.8, score=73.6]; Methyltransferase domain [PF13489.8, score=61.5]; Methyltransferase domain [PF08242.14, score=51.0]; Methyltransferase domain [PF13847.8, score=50.3]; ubiE/COQ5 methyltransferase family [PF01209.20, score=50.2]; Mycolic acid cyclopropane synthetase [PF02353.22, score=42.9]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=23.1]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=22.1]; Methyltransferase small domain [PF05175.16, score=21.3]; Tellurite resistance protein TehB [PF03848.16, score=20.1]} {Dmel: FBgn0032922, CG9249, [Score=47.8, Expect=4e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=182, Expect=1e-54]} {RNA1509_20289, RNA1509_5276, RNA1509_6525} {RNA1310_20797, RNA1509_20289, RNA1509_5276} {RNA1509_20289, RNA1509_5276, RNA815_10580.1}

Mlig455_013235 {REF} {Length: 1347} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=77.6]; Methyltransferase domain [PF13649.8, score=73.4]; Methyltransferase domain [PF13489.8, score=59.4]; Methyltransferase domain [PF08242.14, score=50.7]; Methyltransferase domain [PF13847.8, score=50.0]; ubiE/COQ5 methyltransferase family [PF01209.20, score=49.1]; Mycolic acid cyclopropane synthetase [PF02353.22, score=41.7]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=21.8]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=21.4]; Methyltransferase small domain [PF05175.16, score=19.5]} {Dmel: FBgn0032922, CG9249, [Score=48.1, Expect=3e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=181, Expect=4e-54]} {RNA1509_2488, RNA1509_52745, RNA1509_6525} {RNA1310_20797, RNA1509_2488, RNA1509_52745, RNA1509_6525} {RNA1509_2488, RNA1509_52745, RNA1509_6525, RNA815_10580.1}

Mlig455_013307 {REF} {Length: 1338} {TRANSSPLICED} {Pfam: Methyltransferase domain [PF08241.14, score=78.1]; Methyltransferase domain [PF13649.8, score=73.6]; Methyltransferase domain [PF13489.8, score=61.5]; Methyltransferase domain [PF08242.14, score=51.0]; Methyltransferase domain [PF13847.8, score=50.3]; ubiE/COQ5 methyltransferase family [PF01209.20, score=50.2]; Mycolic acid cyclopropane synthetase [PF02353.22, score=42.9]; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=23.1]; AdoMet dependent proline di-methyltransferase [PF05891.14, score=22.1]; Methyltransferase small domain [PF05175.16, score=21.3]; Tellurite resistance protein TehB [PF03848.16, score=20.1]} {Dmel: FBgn0032922, CG9249, [Score=47.8, Expect=4e-06]} {Celegans: WBGene00018811, pmt-2, Phosphoethanolamine MethylTransferase, [RH, Score=182, Expect=1e-54]} {RNA1509_6525} {RNA1310_20797} {RNA815_10580.1}
14. MligTC455_50759 478 9.97 Mlig455_057899

Neo: -

Age: -

 2.597 0.812 - - 0.979 - 0.806 Mlig455_057899 {REF} {Length: 535} {RNA1509_29040} {RNA1310_42952} {RNA815_48443}
15. MligTC455_19714 956 19.91 Mlig455_002912, Mlig455_002914

Neo: -

Age: Down-Down-Up

 RIDA 2.593 - - - 0.966 0.750 0.877

Mlig455_002912 {REF} {Length: 1773} {TRANSSPLICED} {Pfam: Endoribonuclease L-PSP [PF01042.23, score=99.4]} {Human: ENSG00000132541, RIDA, reactive intermediate imine deaminase A homolog, [Score=117, Expect=5e-34]} {Mouse: ENSMUSG00000022323, Rida, reactive intermediate imine deaminase A homolog, [Score=115, Expect=2e-33]} {Dmel: FBgn0086691, UK114, [Score=81.6, Expect=2e-20]} {Celegans: WBGene00016011, C23G10.2, RutC family protein C23G10.2, [Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1895_0_1, dd_Smed_v6_1895_0_1, [Score=118, Expect=4e-35]} {RNA1509_22089} {RNA1310_28404} {RNA815_23611}

Mlig455_002914 {REF} {Length: 1069} {TRANSSPLICED} {Pfam: Endoribonuclease L-PSP [PF01042.23, score=99.4]} {Human: ENSG00000132541, RIDA, reactive intermediate imine deaminase A homolog, [Score=117, Expect=5e-34]} {Mouse: ENSMUSG00000022323, Rida, reactive intermediate imine deaminase A homolog, [Score=115, Expect=2e-33]} {Dmel: FBgn0086691, UK114, [Score=81.6, Expect=2e-20]} {Celegans: WBGene00016011, C23G10.2, RutC family protein C23G10.2, [Score=104, Expect=2e-29]} {Smed: dd_Smed_v6_1895_0_1, dd_Smed_v6_1895_0_1, [Score=118, Expect=4e-35]} {RNA1509_22089} {RNA1310_28404} {RNA815_23611}
16. MligTC455_11541 5219 108.72 Mlig455_044738

Neo: -

Age: logFC(26M/2M)=-1.585

Region-enriched R5: 1.510/0.00319
Region-enriched R4: 1.344/0.03467

 2.583 - - - 0.746 0.954 0.883 Mlig455_044738 {REF} {Length: 705} {RNA1509_21633} {RNA1310_61939, RNA1509_21633} {RNA1509_21633, RNA815_30221.2}
17. MligTC455_42649 1111 23.15 Mlig455_033920

Neo: -

Age: logFC(26M/2M)=0.288

 TPTE2 2.538 - - - 0.964 0.721 0.853 Mlig455_033920 {REF} {Length: 2398} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=66.0]; Ion transport protein [PF00520.33, score=35.9]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=28.9]; Protein-tyrosine phosphatase [PF00102.29, score=24.5]; Inositol hexakisphosphate [PF14566.8, score=22.0]} {Human: ENSG00000132958, TPTE2, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2, [RH, Score=373, Expect=6e-124]} {Mouse: ENSMUSG00000031481, Tpte, transmembrane phosphatase with tensin homology, [RH, Score=384, Expect=1e-126]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=171, Expect=9e-48]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=137, Expect=5e-34]} {Smed: dd_Smed_v6_4925_0_2, dd_Smed_v6_4925_0_2, [RH, Score=424, Expect=7e-145]} {RNA1509_26060, RNA1509_6952} {RNA1310_16625.1, RNA1509_26060, RNA1509_6952} {RNA1509_26060, RNA1509_6952, RNA815_5966}
18. MligTC455_42518 397 8.27 Mlig455_061703

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.454

Region-enriched R6: 2.767/0.02583

Regeneration-enriched R5: 3.056
Regeneration-enriched R4: 2.829

 HES1 2.508 - - - 0.957 0.829 0.722 Mlig455_061703 {REF} {Length: 1173} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=39.6]} {Human: ENSG00000114315, HES1, hes family bHLH transcription factor 1, [Score=58.9, Expect=2e-10]} {Mouse: ENSMUSG00000022528, Hes1, hes family bHLH transcription factor 1, [Score=58.5, Expect=1e-10]} {Dmel: FBgn0010109, dpn, deadpan, [Score=64.3, Expect=1e-12]} {Celegans: WBGene00003008, lin-22, Lin-22, [Score=45.8, Expect=1e-06]} {Smed: dd_Smed_v6_17332_0_1, dd_Smed_v6_17332_0_1, [Score=43.9, Expect=6e-06]} {RNA1310_30690} {RNA815_13906}
19. MligTC455_52026 1687 35.15 Mlig455_004669, Mlig455_004733, Mlig455_004832

Neo: -

Age: logFC(26M/2M)=0.290

Region-enriched R5: 1.467/0.04312

 1.906 - - - 0.988 0.918 -

Mlig455_004669 {REF} {Length: 1728} {RNA1509_23759} {RNA1310_39844} {RNA815_18443.1}

Mlig455_004733 {REF} {Length: 2712} {RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1310_39844, RNA1509_23759, RNA1509_38591, RNA1509_46380} {RNA1509_23759, RNA1509_38591, RNA1509_46380, RNA815_18443.1}

Mlig455_004832 {REF} {Length: 1806} {RNA1509_23759, RNA1509_55627} {RNA1310_39844, RNA1509_55627} {RNA1509_55627, RNA815_18443.1}
20. MligTC455_41507 683 14.22 Mlig455_029753, Mlig455_029849

Neo: -

Age: -

Region-enriched R4: 2.180/0.02027
Region-enriched R5: 1.936/0.00260

 1.896 - - - 0.952 - 0.944

Mlig455_029753 {REF} {Length: 2787} {TRANSSPLICED} {RNA1509_43940} {RNA1310_30266, RNA1509_43940} {RNA1509_43940, RNA815_27401}

Mlig455_029849 {REF} {Length: 3264} {TRANSSPLICED} {RNA1509_43940} {RNA1310_30266} {RNA815_27401}
21. MligTC455_04428 655 13.66 Mlig455_071088

Neo: -

Age: -

Region-enriched R4: 3.160/0.00859

 1.873 - - - 0.970 - 0.903 Mlig455_071088 {REF} {Length: 272} {NoTransDecoderORF} {RNA1509_284} {RNA1310_24413} {RNA815_6153}
22. MligTC455_31181 3530 73.55 Mlig455_051856, Mlig455_051892

Neo: -

Age: -

Region-enriched R6: 1.979/0.00019
Region-enriched R5: 1.598/0.00061
Region-enriched R3: 1.383/0.02407
Region-enriched R4: 1.335/0.03212

 ANPEP, ERAP1 1.869 - - - 0.968 0.901 -

Mlig455_051856 {REF} {Length: 5257} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=263.7]; Peptidase family M1 domain [PF01433.22, score=247.0]; Peptidase M1 N-terminal domain [PF17900.3, score=143.0]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [RH, Score=578, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=565, Expect=0.0]} {Dmel: FBgn0039640, CG14516, [RH, Score=545, Expect=4e-178]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [RH, Score=438, Expect=9e-138]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [RH, Score=644, Expect=0.0]} {RNA1509_14294, RNA1509_1573, RNA1509_20439} {RNA1310_1662.1, RNA1509_14294, RNA1509_20439} {RNA1509_14294, RNA1509_20439, RNA815_486.1}

Mlig455_051892 {REF} {Length: 3530} {Pfam: Peptidase family M1 domain [PF01433.22, score=52.4]; ERAP1-like C-terminal domain [PF11838.10, score=39.9]; FimH, mannose binding [PF09160.12, score=18.4]} {Human: ENSG00000164307, ERAP1, endoplasmic reticulum aminopeptidase 1, [Score=108, Expect=5e-26]; ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=105, Expect=3e-25]} {Mouse: ENSMUSG00000021583, Erap1, endoplasmic reticulum aminopeptidase 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0039656, CG11951, [Score=92.0, Expect=9e-21]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=100, Expect=7e-24]} {Smed: dd_Smed_v6_1249_0_1, dd_Smed_v6_1249_0_1, [Score=95.9, Expect=2e-22]} {RNA1509_13872} {RNA1310_1662.1} {RNA815_3255}
23. MligTC455_35519 1708 35.59 Mlig455_014621

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.589

Region-enriched R4: 1.911/0.00012
Region-enriched R3: 1.380/0.00213
Region-enriched R5: 1.309/0.00075

 SLC44A2 1.851 - - - 0.957 - 0.894 Mlig455_014621 {REF} {Length: 3582} {Pfam: Plasma-membrane choline transporter [PF04515.14, score=313.8]} {Human: ENSG00000129353, SLC44A2, solute carrier family 44 member 2, [Score=436, Expect=1e-142]} {Mouse: ENSMUSG00000057193, Slc44a2, solute carrier family 44, member 2, [Score=451, Expect=7e-149]} {Dmel: FBgn0039637, Ctl2, Choline transporter-like 2, [Score=315, Expect=4e-96]} {Celegans: WBGene00018037, chtl-1, Choline transporter-like protein 1, [Score=373, Expect=1e-118]} {Smed: dd_Smed_v6_6488_0_1, dd_Smed_v6_6488_0_1, [Score=434, Expect=7e-142]} {RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1310_8213, RNA1509_14161, RNA1509_56009, RNA1509_8961} {RNA1509_14161, RNA1509_56009, RNA1509_8961, RNA815_109}
24. MligTC455_50450 289 6.03 Mlig455_025789

Neo: -

Age: -

Region-enriched R4: 2.436/0.00472

 GRHPR 1.804 - - - 0.957 - 0.847 Mlig455_025789 {REF} {Length: 1745} {TRANSSPLICED} {Pfam: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain [PF02826.21, score=175.7]; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [PF00389.32, score=56.3]; NAD binding domain of 6-phosphogluconate dehydrogenase [PF03446.17, score=23.6]} {Human: ENSG00000137106, GRHPR, glyoxylate and hydroxypyruvate reductase, [Score=168, Expect=4e-49]} {Mouse: ENSMUSG00000035637, Grhpr, glyoxylate reductase/hydroxypyruvate reductase, [Score=169, Expect=9e-50]} {Dmel: FBgn0032889, CG9331, [Score=138, Expect=4e-38]} {Celegans: WBGene00007836, C31C9.2, [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_20441_0_1, dd_Smed_v6_20441_0_1, [RH, Score=157, Expect=5e-47]} {RNA1509_9527} {RNA1310_17599} {RNA815_26280}
25. MligTC455_39350 538 11.21 Mlig455_023484

Neo: -

Age: Down-Up-Down

Region-enriched R4: 3.492/0.00082
Region-enriched R5: 2.753/0.00156

 RAB8B 1.798 - - - 0.952 0.846 - Mlig455_023484 {REF} {Length: 1074} {Pfam: Ras family [PF00071.24, score=174.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.8]; ADP-ribosylation factor family [PF00025.23, score=55.3]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=152, Expect=1e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=2e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=2e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=152, Expect=6e-46]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=147, Expect=3e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=145, Expect=5e-43]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=5e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=5e-52]} {RNA1509_19859, RNA1509_27459} {RNA1310_37116, RNA1509_27459} {RNA1509_27459, RNA815_17007}
26. MligTC455_38510 179 3.74 Mlig455_014760

Neo: -

Age: -

 PHKB 1.781 - - - 0.965 0.816 - Mlig455_014760 {REF} {Length: 5132} {TRANSSPLICED} {Pfam: Glycosyl hydrolases family 15 [PF00723.23, score=263.2]; Phosphorylase b kinase C-terminal domain [PF19292.1, score=57.5]} {Human: ENSG00000102893, PHKB, phosphorylase kinase regulatory subunit beta, [RH, Score=724, Expect=0.0]} {Mouse: ENSMUSG00000036879, Phkb, phosphorylase kinase beta, [RH, Score=712, Expect=0.0]} {Dmel: FBgn0031995, CG8475, [RH, Score=721, Expect=0.0]} {Celegans: WBGene00022059, Y67D8A.2, [RH, Score=639, Expect=0.0]} {Smed: dd_Smed_v6_3657_0_1, dd_Smed_v6_3657_0_1, [RH, Score=934, Expect=0.0]} {RNA1509_31508} {RNA1310_3293} {RNA815_960}
27. MligTC455_47202 347 7.23 Mlig455_067347

Neo: -

Age: -

 1.771 - - - 0.963 0.808 - Mlig455_067347 {REF} {Length: 3673} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=78.5]; C2H2 type zinc-finger (2 copies) [PF12756.9, score=26.9]; C2H2-type zinc finger [PF13894.8, score=21.6]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=21.2]} {Dmel: FBgn0028979, tio, tiptop, [RH, Score=75.1, Expect=3e-13]} {Smed: dd_Smed_v6_9287_0_1, dd_Smed_v6_9287_0_1, [Score=131, Expect=9e-31]} {RNA1509_33943} {RNA1310_12382} {RNA815_29092}
28. MligTC455_23618 5999 124.98 Mlig455_017118

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.199

 PPIB 1.739 - - - - 0.959 0.780 Mlig455_017118 {REF} {Length: 3287} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=164.8]} {Human: ENSG00000166794, PPIB, peptidylprolyl isomerase B, [RH, Score=266, Expect=2e-90]} {Mouse: ENSMUSG00000032383, Ppib, peptidylprolyl isomerase B, [RH, Score=262, Expect=7e-89]} {Dmel: FBgn0034753, CG2852, [RH, Score=278, Expect=1e-95]} {Celegans: WBGene00000882, cyn-6, Peptidyl-prolyl cis-trans isomerase 6, [RH, Score=277, Expect=1e-95]} {Smed: dd_Smed_v6_686_0_1, dd_Smed_v6_686_0_1, [RH, Score=287, Expect=2e-99]} {RNA1509_12660, RNA1509_23043, RNA1509_30186, RNA1509_36965, RNA1509_39363, RNA1509_41601, RNA1509_4829, RNA1509_56402, RNA1509_59479} {RNA1310_20163, RNA1509_12660, RNA1509_23043, RNA1509_30186, RNA1509_36965, RNA1509_39363, RNA1509_41601, RNA1509_4829, RNA1509_56402, RNA1509_59479} {RNA1509_12660, RNA1509_23043, RNA1509_30186, RNA1509_36965, RNA1509_39363, RNA1509_41601, RNA1509_4829, RNA1509_56402, RNA1509_59479, RNA815_8313.1}
29. MligTC455_37964 3298 68.72 Mlig455_056045

Neo: -

Age: logFC(26M/2M)=1.465

 HSD17B4 1.738 - - - 0.961 - 0.777 Mlig455_056045 {REF} {Length: 2688} {Pfam: short chain dehydrogenase [PF00106.27, score=134.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=112.0]; MaoC like domain [PF01575.21, score=101.4]; SCP-2 sterol transfer family [PF02036.19, score=70.6]; KR domain [PF08659.12, score=53.8]} {Human: ENSG00000133835, HSD17B4, hydroxysteroid 17-beta dehydrogenase 4, [RH, Score=810, Expect=0.0]} {Mouse: ENSMUSG00000024507, Hsd17b4, hydroxysteroid (17-beta) dehydrogenase 4, [RH, Score=781, Expect=0.0]} {Dmel: FBgn0030731, Mfe2, peroxisomal Multifunctional enzyme type 2, [RH, Score=595, Expect=0.0]} {Celegans: WBGene00000991, dhs-28, DeHydrogenases, Short chain, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_5867_0_1, dd_Smed_v6_5867_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_9012} {RNA1310_590.1} {RNA815_2204}
30. MligTC455_34754 1515 31.57 Mlig455_040390, Mlig455_040396

Neo: -

Age: -

Region-enriched R5: 1.522/0.00861

 PFKM 1.72 - - - 0.954 0.766 -

Mlig455_040390 {REF} {Length: 5737} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=551.3]; Integrase core domain [PF00665.28, score=28.9]} {Human: ENSG00000152556, PFKM, phosphofructokinase, muscle, [Score=511, Expect=8e-163]; ENSG00000067057, PFKP, phosphofructokinase, platelet, [Score=501, Expect=7e-160]; ENSG00000141959, PFKL, phosphofructokinase, liver type, [Score=495, Expect=9e-158]} {Mouse: ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [Score=508, Expect=8e-163]; ENSMUSG00000020277, Pfkl, phosphofructokinase, liver, B-type, [Score=498, Expect=8e-159]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [Score=494, Expect=1e-157]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [Score=517, Expect=4e-166]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [Score=501, Expect=5e-160]} {Smed: dd_Smed_v6_3613_0_1, dd_Smed_v6_3613_0_1, [Score=571, Expect=0.0]} {RNA1509_11643} {RNA1310_2251.4} {RNA815_8327}

Mlig455_040396 {REF} {Length: 3871} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=611.5]} {Human: ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=837, Expect=0.0]} {Mouse: ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=832, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=814, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [Score=826, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=810, Expect=0.0]} {Smed: dd_Smed_v6_3613_0_1, dd_Smed_v6_3613_0_1, [Score=864, Expect=0.0]} {RNA1509_11643, RNA1509_13268, RNA1509_33375, RNA1509_53165} {RNA1310_2251.2, RNA1509_13268, RNA1509_33375, RNA1509_53165} {RNA1509_13268, RNA1509_33375, RNA1509_53165, RNA815_2567}
31. MligTC455_36696 1081 22.51 Mlig455_029781, Mlig455_029931

Neo: Irradiation

Age: -

Region-specific R5: 3.121

Region-enriched R5: 2.340/0.00000

 NOTCH1 1.709 - - - 0.951 0.758 -

Mlig455_029781 {REF} {Length: 5944} {Pfam: EGF-like domain [PF00008.29, score=196.5]; Ankyrin repeats (3 copies) [PF12796.9, score=151.2]; Human growth factor-like EGF [PF12661.9, score=101.4]; Ankyrin repeat [PF00023.32, score=79.2]; Ankyrin repeat [PF13606.8, score=73.4]; Ankyrin repeats (many copies) [PF13857.8, score=70.0]; Ankyrin repeats (many copies) [PF13637.8, score=66.1]; LNR domain [PF00066.19, score=63.4]; EGF-like domain [PF07974.15, score=53.4]; Calcium-binding EGF domain [PF07645.17, score=32.5]; Alliinase EGF-like domain [PF04863.15, score=23.6]; EGF domain [PF12947.9, score=19.7]} {Human: ENSG00000148400, NOTCH1, notch 1, [RH, Score=529, Expect=6e-156]; ENSG00000234876, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000223355, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000235396, NOTCH4, notch 4, [RH, Score=518, Expect=6e-154]; ENSG00000204301, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000232339, NOTCH4, notch 4, [RH, Score=518, Expect=7e-154]; ENSG00000206312, NOTCH4, notch 4, [RH, Score=516, Expect=3e-153]; ENSG00000074181, NOTCH3, notch 3, [RH, Score=515, Expect=1e-151]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [RH, Score=526, Expect=2e-155]} {Dmel: FBgn0004647, N, Notch, [RH, Score=541, Expect=4e-160]} {Celegans: WBGene00001609, glp-1, [RH, Score=262, Expect=5e-71]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [RH, Score=386, Expect=2e-109]} {RNA1509_4917} {RNA1310_700} {RNA815_15747}

Mlig455_029931 {REF} {Length: 6142} {Pfam: EGF-like domain [PF00008.29, score=185.5]; Ankyrin repeats (3 copies) [PF12796.9, score=151.2]; Human growth factor-like EGF [PF12661.9, score=95.1]; Ankyrin repeat [PF00023.32, score=79.2]; Ankyrin repeat [PF13606.8, score=73.5]; Ankyrin repeats (many copies) [PF13857.8, score=70.1]; Ankyrin repeats (many copies) [PF13637.8, score=66.0]; EGF-like domain [PF07974.15, score=63.3]; LNR domain [PF00066.19, score=62.5]; Calcium-binding EGF domain [PF07645.17, score=32.8]; Alliinase EGF-like domain [PF04863.15, score=23.6]; EGF domain [PF12947.9, score=19.8]} {Human: ENSG00000148400, NOTCH1, notch 1, [RH, Score=527, Expect=2e-155]; ENSG00000234876, NOTCH4, notch 4, [RH, Score=520, Expect=2e-154]; ENSG00000204301, NOTCH4, notch 4, [RH, Score=520, Expect=2e-154]; ENSG00000223355, NOTCH4, notch 4, [RH, Score=520, Expect=3e-154]; ENSG00000232339, NOTCH4, notch 4, [RH, Score=520, Expect=2e-154]; ENSG00000235396, NOTCH4, notch 4, [RH, Score=519, Expect=4e-154]; ENSG00000206312, NOTCH4, notch 4, [RH, Score=516, Expect=3e-153]; ENSG00000074181, NOTCH3, notch 3, [RH, Score=511, Expect=2e-150]} {Mouse: ENSMUSG00000026923, Notch1, notch 1, [RH, Score=546, Expect=5e-162]; ENSMUSG00000038146, Notch3, notch 3, [RH, Score=521, Expect=8e-154]} {Dmel: FBgn0004647, N, Notch, [RH, Score=588, Expect=3e-176]} {Celegans: WBGene00003001, lin-12, [RH, Score=282, Expect=4e-77]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=388, Expect=4e-110]} {RNA1509_4917} {RNA1310_700, RNA1509_4917} {RNA1509_4917, RNA815_15747}
32. MligTC455_46995 445 9.27 Mlig455_039509

Neo: -

Age: logFC(26M/2M)=0.375

 USB1 1.685 0.727 - - 0.958 - - Mlig455_039509 {REF} {Length: 2185} {TRANSSPLICED} {Pfam: Uncharacterised conserved protein [PF09749.11, score=128.8]} {Human: ENSG00000103005, USB1, U6 snRNA biogenesis phosphodiesterase 1, [RH, Score=115, Expect=2e-30]} {Mouse: ENSMUSG00000031792, Usb1, U6 snRNA biogenesis 1, [RH, Score=120, Expect=2e-32]} {Dmel: FBgn0037713, CG16790, [RH, Score=120, Expect=1e-32]} {RNA1509_23851} {RNA1310_12885.1} {RNA815_5897}
33. MligTC455_16507 120 2.5 Mlig455_062916

Neo: -

Age: -

 CTNS 0.97 - - - 0.970 - - Mlig455_062916 {REF} {Length: 2187} {Pfam: PQ loop repeat [PF04193.16, score=98.2]} {Human: ENSG00000040531, CTNS, cystinosin, lysosomal cystine transporter, [Score=252, Expect=4e-79]} {Mouse: ENSMUSG00000005949, Ctns, cystinosis, nephropathic, [Score=246, Expect=2e-77]} {Dmel: FBgn0039045, CG17119, [RH, Score=269, Expect=4e-86]} {Celegans: WBGene00008052, ctns-1, Cystinosin homolog, [RH, Score=228, Expect=2e-70]} {Smed: dd_Smed_v6_4571_0_1, dd_Smed_v6_4571_0_1, [RH, Score=271, Expect=8e-88]} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1310_18560, RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307} {RNA1509_13472, RNA1509_49983, RNA1509_53579, RNA1509_8307, RNA815_7181}
34. MligTC455_53953 1355 28.23 Mlig455_034731

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.235

Region-enriched R4: 1.589/0.02363

 GLUD1 0.964 - - - 0.964 - - Mlig455_034731 {REF} {Length: 2660} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=194.2]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=169.3]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [RH, Score=777, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [RH, Score=765, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [RH, Score=781, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [RH, Score=746, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [RH, Score=640, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [RH, Score=715, Expect=0.0]} {RNA1509_10612, RNA1509_40304} {RNA1310_5462.1, RNA1509_10612, RNA1509_40304} {RNA1509_10612, RNA1509_40304, RNA815_2103.2}
35. MligTC455_18116 1101 22.93 Mlig455_034507

Neo: -

Age: -

Region-enriched R6: 2.069/0.00170
Region-enriched R5: 1.877/0.00089

 AP2S1 0.962 - - - 0.962 - - Mlig455_034507 {REF} {Length: 3004} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=204.0]} {Human: ENSG00000042753, AP2S1, adaptor related protein complex 2 subunit sigma 1, [RH, Score=269, Expect=3e-94]} {Mouse: ENSMUSG00000008036, Ap2s1, adaptor-related protein complex 2, sigma 1 subunit, [RH, Score=269, Expect=2e-94]} {Dmel: FBgn0043012, AP-2sigma, Adaptor Protein complex 2, sigma subunit, [RH, Score=265, Expect=7e-93]} {Celegans: WBGene00000157, aps-2, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=268, Expect=2e-94]} {Smed: dd_Smed_v6_3529_0_1, dd_Smed_v6_3529_0_1, [RH, Score=257, Expect=6e-90]} {RNA1509_11642, RNA1509_3682, RNA1509_37240, RNA1509_53443, RNA1509_60138, RNA1509_8028} {RNA1310_34747, RNA1509_11642, RNA1509_3682, RNA1509_53443, RNA1509_60138, RNA1509_8028} {RNA1509_11642, RNA1509_3682, RNA1509_53443, RNA1509_60138, RNA1509_8028, RNA815_7668.1}
36. MligTC455_18117 1092 22.75 Mlig455_066275

Neo: -

Age: logFC(26M/2M)=0.355

Region-enriched R6: 2.041/0.00226
Region-enriched R5: 1.905/0.00060

 AP2S1 0.962 - - - 0.962 - - Mlig455_066275 {REF} {Length: 1943} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=204.0]} {Human: ENSG00000042753, AP2S1, adaptor related protein complex 2 subunit sigma 1, [RH, Score=269, Expect=3e-94]} {Mouse: ENSMUSG00000008036, Ap2s1, adaptor-related protein complex 2, sigma 1 subunit, [RH, Score=269, Expect=2e-94]} {Dmel: FBgn0043012, AP-2sigma, Adaptor Protein complex 2, sigma subunit, [RH, Score=265, Expect=7e-93]} {Celegans: WBGene00000157, aps-2, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=268, Expect=2e-94]} {Smed: dd_Smed_v6_3529_0_1, dd_Smed_v6_3529_0_1, [RH, Score=257, Expect=6e-90]} {RNA1509_11775, RNA1509_37240} {RNA1310_34747, RNA1509_11775, RNA1509_37240} {RNA1509_11775, RNA1509_37240, RNA815_7668.1}
37. MligTC455_39351 815 16.99 Mlig455_068114

Neo: -

Age: -

 RAB8B 0.96 - - - 0.960 - - Mlig455_068114 {REF} {Length: 1704} {Pfam: Ras family [PF00071.24, score=174.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.7]; ADP-ribosylation factor family [PF00025.23, score=55.4]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=151, Expect=2e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [Score=145, Expect=6e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=3e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=3e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=151, Expect=1e-45]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=148, Expect=2e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=144, Expect=2e-42]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [Score=144, Expect=3e-42]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=6e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=6e-52]} {RNA1509_18167, RNA1509_19859} {RNA1310_37116, RNA1509_18167, RNA1509_19859} {RNA1509_18167, RNA1509_19859, RNA815_17007}
38. MligTC455_22000 646 13.45 Mlig455_042166

Neo: -

Age: -

Region-specific R5: 4.983

Region-enriched R5: 4.561/0.00000
Region-enriched R6: 2.361/0.01711

Regeneration-upregulated R4: 2.507

Regeneration-enriched R4: 2.507

 SLC47A1 0.956 - - - 0.956 - - Mlig455_042166 {REF} {Length: 2839} {Pfam: MatE [PF01554.20, score=185.2]; Polysaccharide biosynthesis C-terminal domain [PF14667.8, score=29.4]} {Human: ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=300, Expect=6e-93]} {Mouse: ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=309, Expect=6e-97]} {Smed: dd_Smed_v6_7241_0_1, dd_Smed_v6_7241_0_1, [Score=410, Expect=6e-135]} {RNA1509_32271, RNA1509_50596} {RNA1310_8561.1, RNA1509_32271, RNA1509_50596} {RNA1509_32271, RNA1509_50596, RNA815_2534.1}
39. MligTC455_13616 373 7.77 Mlig455_063500

Neo: -

Age: Down-Down-Up

 SLC47A1 0.954 - - - - 0.954 - Mlig455_063500 {REF} {Length: 1898} {Pfam: MatE [PF01554.20, score=96.5]} {Human: ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=143, Expect=7e-37]} {Mouse: ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=144, Expect=2e-37]} {Smed: dd_Smed_v6_7241_0_1, dd_Smed_v6_7241_0_1, [Score=187, Expect=8e-53]} {RNA1509_33085} {RNA1310_12101} {RNA815_32639}
40. MligTC455_14821 305 6.35 Mlig455_018773

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.196/0.03323
Region-enriched R5: 1.788/0.02997

 PANK1 0.954 - - - 0.954 - - Mlig455_018773 {REF} {Length: 2765} {Pfam: Fumble [PF03630.16, score=101.1]} {Human: ENSG00000152782, PANK1, pantothenate kinase 1, [Score=55.5, Expect=6e-08]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=79.7, Expect=9e-16]} {Dmel: FBgn0011205, fbl, fumble, [Score=56.2, Expect=2e-08]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=73.2, Expect=5e-14]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=182, Expect=4e-54]} {RNA1509_12016} {RNA1310_16423} {RNA815_7574.1}
41. MligTC455_41002 233 4.84 Mlig455_022813

Neo: -

Age: -

 PNPLA2 0.954 - - - 0.954 - - Mlig455_022813 {REF} {Length: 4359} {TRANSSPLICED} {Pfam: Patatin-like phospholipase [PF01734.24, score=37.5]} {Human: ENSG00000177666, PNPLA2, patatin like phospholipase domain containing 2, [RH, Score=206, Expect=8e-59]} {Mouse: ENSMUSG00000025509, Pnpla2, patatin-like phospholipase domain containing 2, [RH, Score=203, Expect=4e-58]} {Dmel: FBgn0036449, bmm, brummer, [RH, Score=247, Expect=5e-74]} {Celegans: WBGene00015484, atgl-1, Patanin-like phospholipase domain-containing protein, [RH, Score=188, Expect=3e-51]} {Smed: dd_Smed_v6_9544_0_1, dd_Smed_v6_9544_0_1, [RH, Score=224, Expect=1e-65]} {RNA1509_22408, RNA1509_31645} {RNA1310_13835, RNA1509_22408, RNA1509_31645} {RNA1509_22408, RNA1509_31645, RNA815_4510}
42. MligTC455_38598 960 20 Mlig455_045271, Mlig455_069192

Neo: -

Age: Down-Down-Up

 SYT14 0.952 - - - 0.952 - -

Mlig455_045271 {REF} {Length: 3033} {Pfam: C2 domain [PF00168.32, score=54.5]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [RH, Score=218, Expect=3e-65]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=216, Expect=5e-62]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [RH, Score=223, Expect=6e-66]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [Score=89.0, Expect=3e-19]} {Smed: dd_Smed_v6_9548_0_2, dd_Smed_v6_9548_0_2, [Score=160, Expect=1e-44]} {RNA1509_38023} {RNA1310_12668.1} {RNA815_11664.1}

Mlig455_069192 {REF} {Length: 3053} {Pfam: C2 domain [PF00168.32, score=54.5]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [RH, Score=219, Expect=2e-65]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=216, Expect=4e-62]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [RH, Score=223, Expect=2e-66]} {Celegans: WBGene00004924, snt-4, SyNapTotagmin, [Score=88.6, Expect=4e-19]} {Smed: dd_Smed_v6_9548_0_2, dd_Smed_v6_9548_0_2, [Score=160, Expect=9e-45]} {RNA1509_38023, RNA1509_51042} {RNA1310_12668.1, RNA1509_38023, RNA1509_51042} {RNA1509_38023, RNA1509_51042, RNA815_11664.1}
43. MligTC455_48797 154 3.21 Mlig455_054068

Neo: -

Age: -

 0.952 - - - 0.952 - - Mlig455_054068 {REF} {Length: 3150} {Dmel: FBgn0051195, CG31195, [Score=164, Expect=5e-43]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [Score=264, Expect=4e-78]} {RNA1509_26475} {RNA1310_2842} {RNA815_1220.1}

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