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Results for MligTC455_17592

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_17592 62 1.28 Mlig455_003740

Neo: -

Age: -

Regeneration-downregulated R2: -3.050

Regeneration-depleted R2: -3.050

 PCIF1 Mlig455_003740 {REF} {Length: 2838} {TRANSSPLICED} {Pfam: Phosphorylated CTD interacting factor 1 WW domain [PF12237.10, score=224.4]; WW domain [PF00397.28, score=40.5]} {Human: ENSG00000100982, PCIF1, PDX1 C-terminal inhibiting factor 1, [RH, Score=567, Expect=0.0]} {Mouse: ENSMUSG00000039849, Pcif1, PDX1 C-terminal inhibiting factor 1, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0037021, CG11399, [RH, Score=535, Expect=4e-179]} {Smed: dd_Smed_v6_9161_0_1, dd_Smed_v6_9161_0_1, [RH, Score=459, Expect=9e-153]} {RNA1509_12189} {RNA1310_4645} {RNA815_2873.1}

Cumulative graph for MligTC455_17592

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.599 1.605 1.00000 1.00000
RegionR2 2.568 1.605 0.99966 1.00000
RegionR3 -1.318 1.605 0.99987 1.00000
RegionR4 -1.396 1.605 1.00000 1.00000
RegionR5 0.136 1.605 0.99988 1.00000
RegionR6 0.249 1.605 0.99992 1.00000
RegionR7 -0.345 1.605 0.99978 1.00000
RegionR8 0.706 1.605 0.99987 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -5.315 1.605 0.99994 1.00000
RegenerationR2 -3.05 1.605 0.00001 0.00346 Specific for R2: -3.050
RegenerationR3 -0.615 1.605 0.99988 1.00000
RegenerationR4 -1.799 1.605 0.99970 1.00000
RegenerationR5 -2.249 1.605 0.99980 1.00000
RegenerationR6 -1.938 1.605 0.99968 1.00000
RegenerationBL -1.704 1.605 0.99996 1.00000
RegenerationTP -2.904 1.605 0.99995 1.00000


Genes with expression patterns similar to MligTC455_17592

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_17592 62 1.28 Mlig455_003740

Neo: -

Age: -

Regeneration-downregulated R2: -3.050

Regeneration-depleted R2: -3.050

 PCIF1 2 - - 1.000 - 1.000 - Mlig455_003740 {REF} {Length: 2838} {TRANSSPLICED} {Pfam: Phosphorylated CTD interacting factor 1 WW domain [PF12237.10, score=224.4]; WW domain [PF00397.28, score=40.5]} {Human: ENSG00000100982, PCIF1, PDX1 C-terminal inhibiting factor 1, [RH, Score=567, Expect=0.0]} {Mouse: ENSMUSG00000039849, Pcif1, PDX1 C-terminal inhibiting factor 1, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0037021, CG11399, [RH, Score=535, Expect=4e-179]} {Smed: dd_Smed_v6_9161_0_1, dd_Smed_v6_9161_0_1, [RH, Score=459, Expect=9e-153]} {RNA1509_12189} {RNA1310_4645} {RNA815_2873.1}
2. MligTC455_23641 561 11.68 Mlig455_034290

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.478

 STK33 0.985 - - - - 0.985 - Mlig455_034290 {REF} {Length: 2597} {Pfam: Protein kinase domain [PF00069.27, score=207.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=137.0]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.9]} {Human: ENSG00000130413, STK33, serine/threonine kinase 33, [Score=186, Expect=2e-54]} {Mouse: ENSMUSG00000031027, Stk33, serine/threonine kinase 33, [Score=193, Expect=4e-57]} {Dmel: FBgn0026063, KP78b, [Score=141, Expect=3e-37]} {Celegans: WBGene00009326, F32D8.1, [Score=129, Expect=2e-34]} {Smed: dd_Smed_v6_12461_0_1, dd_Smed_v6_12461_0_1, [RH, Score=232, Expect=4e-74]} {RNA1509_36009} {RNA1310_11665} {RNA815_6928}
3. MligTC455_50052 580 12.08 Mlig455_026909, Mlig455_027066

Neo: -

Age: -

Region-specific R2: 2.801

Region-enriched R2: 1.805/0.00804

 STOM 0.979 - - - - 0.979 -

Mlig455_026909 {REF} {Length: 1737} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.6]; SPFH domain-Band 7 family [PF13421.8, score=19.9]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=358, Expect=4e-124]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=355, Expect=4e-123]} {Dmel: FBgn0260657, CG42540, [Score=361, Expect=4e-124]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [RH, Score=380, Expect=8e-132]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=439, Expect=8e-157]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}

Mlig455_027066 {REF} {Length: 3038} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=105.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=345, Expect=5e-119]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=342, Expect=6e-118]} {Dmel: FBgn0260657, CG42540, [Score=349, Expect=3e-119]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=369, Expect=4e-127]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=427, Expect=9e-152]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}
4. MligTC455_43037 479 9.99 Mlig455_056906, Mlig455_056938

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.148/0.04910

 HUS1 0.974 - - 0.974 - - -

Mlig455_056906 {REF} {Length: 2225} {TRANSSPLICED} {Pfam: Hus1-like protein [PF04005.14, score=189.3]} {Human: ENSG00000136273, HUS1, HUS1 checkpoint clamp component, [RH, Score=190, Expect=2e-58]} {Mouse: ENSMUSG00000020413, Hus1, HUS1 checkpoint clamp component, [RH, Score=174, Expect=3e-52]} {Dmel: FBgn0026417, Hus1-like, [RH, Score=73.2, Expect=1e-14]} {Celegans: WBGene00002042, hus-1, HUS1 related; Hus1-like protein, [RH, Score=87.8, Expect=8e-20]} {Smed: dd_Smed_v6_15678_0_1, dd_Smed_v6_15678_0_1, [RH, Score=157, Expect=5e-46]} {RNA1509_46315, RNA1509_55294} {RNA1310_32092, RNA1509_46315, RNA1509_55294} {RNA1509_46315, RNA1509_55294, RNA815_15081}

Mlig455_056938 {REF} {Length: 1951} {TRANSSPLICED} {Pfam: Hus1-like protein [PF04005.14, score=190.6]} {Human: ENSG00000136273, HUS1, HUS1 checkpoint clamp component, [RH, Score=191, Expect=2e-58]} {Mouse: ENSMUSG00000020413, Hus1, HUS1 checkpoint clamp component, [RH, Score=176, Expect=4e-53]} {Dmel: FBgn0026417, Hus1-like, [RH, Score=73.6, Expect=9e-15]} {Celegans: WBGene00002042, hus-1, HUS1 related; Hus1-like protein, [RH, Score=88.6, Expect=4e-20]} {Smed: dd_Smed_v6_15678_0_1, dd_Smed_v6_15678_0_1, [RH, Score=160, Expect=9e-47]} {RNA1509_48401, RNA1509_51443} {RNA1310_32092, RNA1509_48401, RNA1509_51443} {RNA1509_48401, RNA1509_51443, RNA815_15081}
5. MligTC455_44640 1401 29.18 Mlig455_035983

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.952

 0.971 - - - - 0.971 - Mlig455_035983 {REF} {Length: 2336} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=80.8]} {RNA1509_39912, RNA1509_43112} {RNA1310_34469, RNA1509_39912, RNA1509_43112} {RNA1509_39912, RNA1509_43112, RNA815_15853}
6. MligTC455_07751 326 6.79 Mlig455_017909

Neo: -

Age: logFC(26M/2M)=-0.486

 TTLL4 0.97 - - - - 0.970 - Mlig455_017909 {REF} {Length: 5319} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=290.6]; YheC/D like ATP-grasp [PF14398.8, score=24.8]} {Human: ENSG00000135912, TTLL4, tubulin tyrosine ligase like 4, [Score=501, Expect=5e-158]} {Mouse: ENSMUSG00000033257, Ttll4, tubulin tyrosine ligase-like family, member 4, [Score=516, Expect=9e-164]} {Dmel: FBgn0026147, CG16833, [Score=437, Expect=5e-138]} {Celegans: WBGene00014232, ttll-4, Tubulin polyglutamylase ttll-4, [Score=328, Expect=6e-100]} {Smed: dd_Smed_v6_17034_0_1, dd_Smed_v6_17034_0_1, [RH, Score=553, Expect=2e-178]} {RNA1509_47264, RNA1509_9319} {RNA1310_2103.1, RNA1509_47264, RNA1509_9319} {RNA1509_47264, RNA1509_9319, RNA815_5233}
7. MligTC455_21668 84 1.74 Mlig455_024837

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.324

 PPP3R1 0.97 - - - - 0.970 - Mlig455_024837 {REF} {Length: 1650} {Pfam: EF hand [PF00036.34, score=92.6]; EF-hand domain pair [PF13499.8, score=86.6]; EF-hand domain [PF13405.8, score=74.3]; EF hand [PF13202.8, score=72.6]; EF-hand domain pair [PF13833.8, score=65.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.0]; EF-hand domain [PF14658.8, score=21.7]} {Human: ENSG00000221823, PPP3R1, protein phosphatase 3 regulatory subunit B, alpha, [RH, Score=289, Expect=5e-101]} {Mouse: ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [RH, Score=289, Expect=3e-101]} {Dmel: FBgn0010014, CanB, Calcineurin B, [RH, Score=282, Expect=1e-98]} {Celegans: WBGene00000554, cnb-1, Protein phosphatase 2B regulatory subunit cnb-1, [RH, Score=272, Expect=7e-95]} {Smed: dd_Smed_v6_5589_0_1, dd_Smed_v6_5589_0_1, [RH, Score=281, Expect=1e-98]} {RNA1509_14613} {RNA1310_16848.1} {RNA815_6272}
8. MligTC455_17901 321 6.69 Mlig455_000245

Neo: -

Age: -

 LEKR1 0.968 - - - - 0.968 - Mlig455_000245 {REF} {Length: 1995} {Human: ENSG00000197980, LEKR1, leucine, glutamate and lysine rich 1, [RH, Score=70.9, Expect=2e-13]} {Smed: dd_Smed_v6_16355_0_1, dd_Smed_v6_16355_0_1, [Score=59.7, Expect=4e-10]} {RNA1509_14725} {RNA1310_12283} {RNA815_17365}
9. MligTC455_53021 248 5.17 Mlig455_039734, Mlig455_060892

Neo: -

Age: Down-Down-Up

 0.968 - - - - 0.968 -

Mlig455_039734 {REF} {Length: 1487} {TRANSSPLICED} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}

Mlig455_060892 {REF} {Length: 3436} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}
10. MligTC455_33626 159 3.32 Mlig455_027968

Neo: -

Age: -

 0.967 - - 0.967 - - - Mlig455_027968 {REF} {Length: 4332} {Pfam: Transducer of regulated CREB activity, N terminus [PF12884.9, score=29.6]} {RNA1509_26956} {RNA1310_8476, RNA1509_26956} {RNA1509_26956, RNA815_20817}
11. MligTC455_31296 390 8.12 Mlig455_011781

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.545

 0.966 - - - - 0.966 - Mlig455_011781 {REF} {Length: 941} {RNA1509_29951} {RNA1310_14610.1} {RNA815_17373}
12. MligTC455_31314 2211 46.05 Mlig455_048798

Neo: -

Age: -

 ARGLU1 0.965 - - - - 0.965 - Mlig455_048798 {REF} {Length: 2767} {Pfam: Arginine and glutamate-rich 1 [PF15346.8, score=111.7]} {Human: ENSG00000134884, ARGLU1, arginine and glutamate rich 1, [RH, Score=79.7, Expect=1e-16]} {Mouse: ENSMUSG00000040459, Arglu1, arginine and glutamate rich 1, [RH, Score=79.7, Expect=6e-17]} {Dmel: FBgn0051712, CG31712, [RH, Score=81.6, Expect=1e-17]} {Smed: dd_Smed_v6_6381_0_1, dd_Smed_v6_6381_0_1, [RH, Score=64.3, Expect=4e-12]} {RNA1509_30130, RNA1509_38940} {RNA1310_34850, RNA1509_30130, RNA1509_38940} {RNA1509_30130, RNA1509_38940, RNA815_5433.1}
13. MligTC455_22253 696 14.5 Mlig455_039989

Neo: -

Age: -

 H2AFY 0.964 - - - - 0.964 - Mlig455_039989 {REF} {Length: 2087} {TRANSSPLICED} {Pfam: Macro domain [PF01661.23, score=74.1]; C-terminus of histone H2A [PF16211.7, score=47.3]; Core histone H2A/H2B/H3/H4 [PF00125.26, score=33.0]} {Human: ENSG00000113648, H2AFY, H2A histone family member Y, [RH, Score=280, Expect=4e-91]} {Mouse: ENSMUSG00000015937, H2afy, H2A histone family, member Y, [RH, Score=280, Expect=3e-91]} {Dmel: FBgn0053853, His2A:CG33853, [Score=125, Expect=5e-35]} {Celegans: WBGene00001909, his-35, Histone H2A, [Score=118, Expect=2e-32]} {Smed: dd_Smed_v6_4487_0_1, dd_Smed_v6_4487_0_1, [RH, Score=241, Expect=2e-76]} {RNA1509_21701} {RNA1310_14229, RNA1509_21701} {RNA1509_21701, RNA815_13070}
14. MligTC455_50807 576 12.01 Mlig455_028496

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.245/0.00284

 0.964 - - - - 0.964 - Mlig455_028496 {REF} {Length: 937} {Pfam: Pancreatic hormone peptide [PF00159.20, score=40.1]} {RNA1509_25155} {RNA1310_44043, RNA1509_25155} {RNA1509_25155, RNA815_21709}
15. MligTC455_46225 70 1.46 Mlig455_031511

Neo: -

Age: -

 0.963 - - 0.963 - - - Mlig455_031511 {REF} {Length: 4676} {NoTransDecoderORF} {RNA1509_25000} {RNA1310_43728} {RNA815_50636}
16. MligTC455_50844 224 4.67 Mlig455_018511

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.591/0.00005

 SSUH2 0.961 - - - - 0.961 - Mlig455_018511 {REF} {Length: 1843} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=120, Expect=2e-29]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=95.5, Expect=3e-21]} {RNA1509_39980} {RNA1310_60742, RNA1509_39980} {RNA1509_39980, RNA815_28938}
17. MligTC455_17235 216 4.51 Mlig455_058265

Neo: -

Age: -

 ANO7 0.96 - - - - 0.960 - Mlig455_058265 {REF} {Length: 1888} {Pfam: Calcium-activated chloride channel [PF04547.14, score=264.3]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=394, Expect=4e-129]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=392, Expect=9e-130]} {Dmel: FBgn0038721, subdued, [Score=268, Expect=5e-82]} {Celegans: WBGene00013326, anoh-2, Anoctamin, [Score=85.1, Expect=9e-18]} {Smed: dd_Smed_v6_19189_0_1, dd_Smed_v6_19189_0_1, [Score=476, Expect=2e-164]} {RNA1509_15570} {RNA1310_7822} {RNA815_20477}
18. MligTC455_32569 388 8.09 Mlig455_037270

Neo: -

Age: -

 IRAK4 0.96 - - - - 0.960 - Mlig455_037270 {REF} {Length: 3195} {Pfam: Protein kinase domain [PF00069.27, score=132.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=110.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.4]} {Human: ENSG00000198001, IRAK4, interleukin 1 receptor associated kinase 4, [Score=78.6, Expect=1e-14]} {Mouse: ENSMUSG00000059883, Irak4, interleukin-1 receptor-associated kinase 4, [Score=82.4, Expect=5e-16]} {Dmel: FBgn0010441, pll, pelle, [Score=75.5, Expect=8e-14]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_9065_0_1, dd_Smed_v6_9065_0_1, [Score=67.8, Expect=4e-12]} {RNA1509_57751, RNA1509_59099} {RNA1310_29366, RNA1509_57751, RNA1509_59099} {RNA1509_57751, RNA1509_59099, RNA815_24983}
19. MligTC455_37537 203 4.23 Mlig455_047747

Neo: -

Age: -

Region-enriched R8: 3.525/0.01192

 KCNC2 0.96 - - - - 0.960 - Mlig455_047747 {REF} {Length: 3532} {Pfam: Ion transport protein [PF00520.33, score=105.8]; BTB/POZ domain [PF02214.24, score=56.8]; Ion channel [PF07885.18, score=52.6]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=216, Expect=4e-60]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=215, Expect=5e-60]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=207, Expect=1e-56]} {Mouse: ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=218, Expect=1e-60]; ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=214, Expect=6e-60]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=230, Expect=1e-65]} {Celegans: WBGene00001202, egl-36, Potassium voltage-gated channel protein egl-36, [Score=211, Expect=5e-59]} {Smed: dd_Smed_v6_9740_0_2, dd_Smed_v6_9740_0_2, [Score=208, Expect=6e-58]} {RNA1509_26535} {RNA1310_14101} {RNA815_34993}
20. MligTC455_43284 529 11.03 Mlig455_006526

Neo: -

Age: logFC(26M/2M)=-0.435

 ARMC3 0.959 - - - - 0.959 - Mlig455_006526 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=100.6]; Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=95.8]; HEAT repeats [PF13646.8, score=73.0]; HEAT repeat [PF02985.24, score=53.9]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=42.3]; HEAT-like repeat [PF13513.8, score=42.2]; V-ATPase subunit H [PF11698.10, score=40.9]; Armadillo-like [PF04826.15, score=28.2]; Adaptin N terminal region [PF01602.22, score=21.9]; Interferon-related developmental regulator (IFRD) [PF05004.15, score=18.7]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=526, Expect=3e-173]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [RH, Score=492, Expect=4e-160]} {Dmel: FBgn0033794, CG13326, [Score=55.5, Expect=2e-07]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_9668} {RNA1310_4998.1, RNA1509_9668} {RNA1509_9668, RNA815_8459}
21. MligTC455_29264 78 1.62 Mlig455_061707

Neo: -

Age: logFC(26M/2M)=1.238

 0.958 - - - - 0.958 - Mlig455_061707 {REF} {Length: 5671} {Pfam: Zinc knuckle [PF00098.25, score=33.9]} {Celegans: WBGene00017210, F07E5.5, [Score=53.5, Expect=3e-07]} {RNA1509_12781} {RNA1310_541.1} {RNA815_23.1}
22. MligTC455_30366 614 12.78 Mlig455_005372, Mlig455_005424, Mlig455_036242

Neo: -

Age: logFC(26M/2M)=-0.322

 C20orf194 0.958 - - - - 0.958 -

Mlig455_005372 {REF} {Length: 2621} {Human: ENSG00000088854, C20orf194, chromosome 20 open reading frame 194, [Score=103, Expect=6e-22]} {Mouse: ENSMUSG00000027309, 4930402H24Rik, RIKEN cDNA 4930402H24 gene, [RH, Score=110, Expect=3e-24]} {Smed: dd_Smed_v6_10121_0_1, dd_Smed_v6_10121_0_1, [Score=89.7, Expect=3e-18]} {RNA1509_13613} {RNA1310_6491.1} {RNA815_2468}

Mlig455_005424 {REF} {Length: 829} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13613} {RNA1310_1263.1} {RNA815_2468}

Mlig455_036242 {REF} {Length: 3746} {Human: ENSG00000088854, C20orf194, chromosome 20 open reading frame 194, [RH, Score=165, Expect=7e-41]} {Mouse: ENSMUSG00000027309, 4930402H24Rik, RIKEN cDNA 4930402H24 gene, [RH, Score=162, Expect=3e-40]} {Smed: dd_Smed_v6_10121_0_1, dd_Smed_v6_10121_0_1, [RH, Score=178, Expect=3e-45]} {RNA1509_13613} {RNA1310_6491.1, RNA1509_13613} {RNA1509_13613, RNA815_2468}
23. MligTC455_52646 1059 22.07 Mlig455_035837

Neo: -

Age: -

Region-enriched R2: 1.308/0.00778

 FBXL13 0.958 - - - - 0.958 - Mlig455_035837 {REF} {Length: 2683} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=92.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=69.2]; Leucine rich repeat [PF13855.8, score=34.6]; F-box-like [PF12937.9, score=21.2]; F-box domain [PF00646.35, score=19.5]} {Human: ENSG00000161040, FBXL13, F-box and leucine rich repeat protein 13, [RH, Score=370, Expect=3e-116]} {Mouse: ENSMUSG00000048520, Fbxl13, F-box and leucine-rich repeat protein 13, [RH, Score=367, Expect=1e-114]} {Dmel: FBgn0038385, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=104, Expect=1e-22]} {Celegans: WBGene00015350, fbxl-1, Uncharacterized F-box/LRR-repeat protein C02F5.7, [Score=122, Expect=2e-29]} {Smed: dd_Smed_v6_14890_0_1, dd_Smed_v6_14890_0_1, [RH, Score=597, Expect=0.0]} {RNA1509_11787, RNA1509_47513} {RNA1310_7673, RNA1509_11787, RNA1509_47513} {RNA1509_11787, RNA1509_47513, RNA815_2345.1}
24. MligTC455_53094 2333 48.61 Mlig455_002734, Mlig455_063350

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.745

Region-enriched R4: 2.207/0.00184

 SOX2 0.958 - - - - 0.958 -

Mlig455_002734 {REF} {Length: 2479} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]; VIT family [PF01988.21, score=19.5]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=1e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=9e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352, RNA1509_11450} {RNA1509_11450, RNA815_15989}

Mlig455_063350 {REF} {Length: 2568} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=2e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=1e-53]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1310_8352, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1509_19275, RNA1509_34805, RNA1509_47357, RNA815_15989}
25. MligTC455_10456 173 3.6 Mlig455_036936

Neo: -

Age: Down-Up-Down

 0.957 - - - - 0.957 - Mlig455_036936 {REF} {Length: 2942} {RNA1509_52192} {RNA1310_9569.2, RNA1509_52192} {RNA1509_52192, RNA815_10835}
26. MligTC455_37310 188 3.92 Mlig455_043635

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=3.872

 ARRDC4 0.957 - - - - 0.957 - Mlig455_043635 {REF} {Length: 2231} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.3]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=44.1]} {Human: ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=70.1, Expect=3e-12]; ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=67.8, Expect=2e-11]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=63.5, Expect=3e-10]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=78.2, Expect=2e-15]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.5, Expect=4e-11]} {RNA1509_13418} {RNA1310_36821} {RNA815_11006.1}
27. MligTC455_48601 72 1.5 Mlig455_042044

Neo: -

Age: -

 SLC35E3 0.957 - - 0.957 - - - Mlig455_042044 {REF} {Length: 1777} {TRANSSPLICED} {Pfam: Triose-phosphate Transporter family [PF03151.18, score=65.8]; EamA-like transporter family [PF00892.22, score=31.7]; UAA transporter family [PF08449.13, score=23.4]} {Human: ENSG00000175782, SLC35E3, solute carrier family 35 member E3, [RH, Score=293, Expect=2e-98]} {Mouse: ENSMUSG00000060181, Slc35e3, solute carrier family 35, member E3, [RH, Score=289, Expect=6e-97]} {RNA1509_18211} {RNA1310_8738.1, RNA1509_18211} {RNA1509_18211, RNA815_11669}
28. MligTC455_22598 323 6.72 Mlig455_012998, Mlig455_070656

Neo: -

Age: -

 0.955 - - - - 0.955 -

Mlig455_012998 {REF} {Length: 3998} {TRANSSPLICED} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=110.6]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=107.9]; Integrase zinc binding domain [PF17921.3, score=52.5]; Integrase core domain [PF00665.28, score=50.7]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=45.6]; gag-polyprotein putative aspartyl protease [PF13975.8, score=29.1]; Aspartyl protease [PF13650.8, score=24.3]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=229, Expect=9e-62]} {RNA1509_5479} {RNA1310_294} {RNA815_755}

Mlig455_070656 {REF} {Length: 4409} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=110.3]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=106.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.0]; gag-polyprotein putative aspartyl protease [PF13975.8, score=30.3]; Aspartyl protease [PF13650.8, score=24.8]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=203, Expect=2e-54]} {RNA1509_5479} {RNA1310_294} {RNA815_755}
29. MligTC455_45181 516 10.76 Mlig455_015976, Mlig455_015996

Neo: -

Age: -

 0.955 - - - - 0.955 -

Mlig455_015976 {REF} {Length: 2623} {Pfam: TIR domain [PF13676.8, score=74.6]} {Smed: dd_Smed_v6_6471_0_1, dd_Smed_v6_6471_0_1, [Score=139, Expect=7e-35]} {RNA1509_16563} {RNA1310_7485} {RNA815_2652}

Mlig455_015996 {REF} {Length: 3380} {Pfam: TIR domain [PF13676.8, score=72.7]} {Smed: dd_Smed_v6_6471_0_1, dd_Smed_v6_6471_0_1, [Score=135, Expect=1e-33]} {RNA1509_16563} {RNA1310_7485, RNA1509_16563} {RNA1509_16563, RNA815_2652}
30. MligTC455_20180 518 10.78 Mlig455_009498

Neo: -

Age: -

 CPNE9 0.954 - - - - 0.954 - Mlig455_009498 {REF} {Length: 4301} {TRANSSPLICED} {Pfam: Copine [PF07002.18, score=236.5]; C2 domain [PF00168.32, score=52.0]; vWA found in TerF C terminus [PF10138.11, score=23.3]} {Human: ENSG00000144550, CPNE9, copine family member 9, [Score=426, Expect=9e-143]; ENSG00000139117, CPNE8, copine 8, [Score=419, Expect=4e-140]} {Mouse: ENSMUSG00000030270, Cpne9, copine family member IX, [Score=427, Expect=2e-143]; ENSMUSG00000052560, Cpne8, copine VIII, [Score=419, Expect=6e-140]} {Celegans: WBGene00012128, nra-1, Nicotinic receptor-associated protein 1, [Score=300, Expect=2e-93]} {Smed: dd_Smed_v6_13873_0_1, dd_Smed_v6_13873_0_1, [RH, Score=570, Expect=0.0]} {RNA1509_22032, RNA1509_32945, RNA1509_37689} {RNA1310_13001, RNA1509_22032, RNA1509_32945, RNA1509_37689} {RNA1509_22032, RNA1509_32945, RNA1509_37689, RNA815_3969.1}
31. MligTC455_32624 513 10.69 Mlig455_049590

Neo: -

Age: -

Region-enriched R2: 2.722/0.00305

 0.954 - - - - 0.954 - Mlig455_049590 {REF} {Length: 2947} {Smed: dd_Smed_v6_7527_0_1, dd_Smed_v6_7527_0_1, [RH, Score=84.0, Expect=5e-17]} {RNA1509_22587} {RNA1310_6575.1, RNA1509_22587} {RNA1509_22587, RNA815_5684.1}
32. MligTC455_33842 492 10.26 Mlig455_004899

Neo: -

Age: -

Region-enriched R2: 2.178/0.01972

 CDKL1 0.953 - - - - 0.953 - Mlig455_004899 {REF} {Length: 2500} {Pfam: Protein kinase domain [PF00069.27, score=247.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.6]; Haspin like kinase domain [PF12330.10, score=18.7]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=429, Expect=3e-150]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=2e-148]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=432, Expect=7e-152]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=423, Expect=3e-148]} {Dmel: FBgn0031730, CG7236, [RH, Score=381, Expect=6e-131]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=396, Expect=4e-136]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=481, Expect=5e-171]} {RNA1509_19679} {RNA1310_6686.1} {RNA815_5397}
33. MligTC455_46066 842 17.54 Mlig455_021428, Mlig455_067222

Neo: -

Age: -

 0.952 - - - - 0.952 -

Mlig455_021428 {REF} {Length: 2125} {TRANSSPLICED} {RNA1509_16610} {RNA1310_5648.3} {RNA815_3911}

Mlig455_067222 {REF} {Length: 2219} {TRANSSPLICED} {RNA1509_16610, RNA1509_38845} {RNA1310_5648.2, RNA1509_16610, RNA1509_38845} {RNA1509_16610, RNA1509_38845, RNA815_3911}
34. MligTC455_23642 573 11.93 Mlig455_069008

Neo: -

Age: logFC(26M/2M)=0.738

 ACTB 0.951 - - - - 0.951 - Mlig455_069008 {REF} {Length: 2243} {Pfam: Actin [PF00022.21, score=267.5]; Protein kinase domain [PF00069.27, score=203.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=20.5]} {Human: ENSG00000075624, ACTB, actin beta, [Score=417, Expect=3e-141]; ENSG00000184009, ACTG1, actin gamma 1, [Score=417, Expect=5e-141]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=4e-136]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=5e-136]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [Score=403, Expect=2e-135]; ENSG00000169067, ACTBL2, actin, beta like 2, [Score=401, Expect=9e-135]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [Score=400, Expect=1e-134]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [Score=417, Expect=4e-141]; ENSMUSG00000029580, Actb, actin, beta, [Score=417, Expect=2e-141]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [Score=404, Expect=2e-136]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [Score=404, Expect=4e-136]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [Score=404, Expect=5e-136]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [Score=403, Expect=1e-135]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [Score=400, Expect=8e-135]} {Dmel: FBgn0000042, Act5C, Actin 5C, [Score=417, Expect=3e-141]} {Celegans: WBGene00000064, act-2, Actin-2, [Score=418, Expect=6e-142]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [Score=419, Expect=4e-142]} {RNA1509_28185} {RNA1310_11665} {RNA815_6928}
35. MligTC455_44600 1240 25.82 Mlig455_058475

Neo: -

Age: Up-Down-Down

 PLCB4 0.951 - - - - 0.951 - Mlig455_058475 {REF} {Length: 6816} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=202.4]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=142.8]; PH domain [PF17787.3, score=115.5]; Protein of unknown function (DUF1154) [PF06631.13, score=41.8]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=31.0]; C2 domain [PF00168.32, score=22.7]} {Human: ENSG00000101333, PLCB4, phospholipase C beta 4, [RH, Score=1318, Expect=0.0]} {Mouse: ENSMUSG00000039943, Plcb4, phospholipase C, beta 4, [RH, Score=1316, Expect=0.0]} {Dmel: FBgn0262738, norpA, no receptor potential A, [RH, Score=547, Expect=8e-175]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [RH, Score=1145, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [Score=1521, Expect=0.0]} {RNA1509_7348} {RNA1310_5860} {RNA815_5854}
36. MligTC455_50024 354 7.37 Mlig455_003621, Mlig455_070701

Neo: -

Age: Down-Up-Down

 ATF7IP 0.951 - - 0.951 - - -

Mlig455_003621 {REF} {Length: 4513} {TRANSSPLICED} {Pfam: Fibronectin-III type domain [PF16794.7, score=92.7]} {Human: ENSG00000171681, ATF7IP, activating transcription factor 7 interacting protein, [RH, Score=103, Expect=8e-22]} {Mouse: ENSMUSG00000030213, Atf7ip, activating transcription factor 7 interacting protein, [RH, Score=101, Expect=2e-21]} {Dmel: FBgn0027499, wde, windei, [RH, Score=90.9, Expect=3e-18]} {Smed: dd_Smed_v6_9372_0_1, dd_Smed_v6_9372_0_1, [RH, Score=75.5, Expect=2e-14]} {RNA1509_10271, RNA1509_53701} {RNA1310_5928.1, RNA1509_53701} {RNA1509_53701, RNA815_4314.1}

Mlig455_070701 {REF} {Length: 4470} {TRANSSPLICED} {RNA1509_10271} {RNA1310_5928.1} {RNA815_4314.1}
37. MligTC455_47216 803 16.72 Mlig455_052798

Neo: -

Age: -

 0.95 - - - - 0.950 - Mlig455_052798 {REF} {Length: 4690} {TRANSSPLICED} {Pfam: Arginine/serine-rich protein PNISR [PF15996.7, score=44.6]} {RNA1509_22491} {RNA1310_7215.1, RNA1509_22491} {RNA1509_22491, RNA815_6578.1}

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