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Results for MligTC455_53094

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53094 2333 48.61 Mlig455_002734, Mlig455_063350

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.745

Region-enriched R4: 2.207/0.00184

SOX2

Mlig455_002734 {REF} {Length: 2479} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]; VIT family [PF01988.21, score=19.5]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=1e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=9e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352, RNA1509_11450} {RNA1509_11450, RNA815_15989}

Mlig455_063350 {REF} {Length: 2568} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=2e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=1e-53]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1310_8352, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1509_19275, RNA1509_34805, RNA1509_47357, RNA815_15989}

Cumulative graph for MligTC455_53094

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -8.702 5.69 0.00034 0.06102
RegionR2 1.031 5.69 0.15103 0.48542
RegionR3 0.832 5.69 0.25339 0.79741
RegionR4 2.207 5.69 0.00012 0.00184
RegionR5 0.761 5.69 0.31252 0.65147
RegionR6 1.523 5.69 0.00511 0.10991
RegionR7 1.509 5.69 0.01165 0.18854
RegionR8 0.839 5.69 0.32427 0.95723

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 7.978 5.69 0.01018 0.44761
RegenerationR2 -0.222 5.69 0.53634 0.88670
RegenerationR3 -0.158 5.69 0.67943 0.94012
RegenerationR4 -0.636 5.69 0.10718 0.50426
RegenerationR5 -0.032 5.69 0.93201 1.00000
RegenerationR6 -0.511 5.69 0.17776 0.51164
RegenerationBL 0.265 5.69 0.46306 0.82972
RegenerationTP -0.263 5.69 0.52278 0.91550


Genes with expression patterns similar to MligTC455_53094

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53094 2333 48.61 Mlig455_002734, Mlig455_063350

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.745

Region-enriched R4: 2.207/0.00184

SOX2 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_002734 {REF} {Length: 2479} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]; VIT family [PF01988.21, score=19.5]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=1e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=9e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352, RNA1509_11450} {RNA1509_11450, RNA815_15989}

Mlig455_063350 {REF} {Length: 2568} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=2e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=1e-53]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1310_8352, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1509_19275, RNA1509_34805, RNA1509_47357, RNA815_15989}
2. MligTC455_19137 807 16.82 Mlig455_067132

Neo: Irradiation

Age: -

KDM4C 1.764 - - - 0.961 0.803 - Mlig455_067132 {REF} {Length: 4923} {TRANSSPLICED} {Pfam: JmjC domain, hydroxylase [PF02373.24, score=145.4]; PHD-zinc-finger like domain [PF13832.8, score=57.1]; jmjN domain [PF02375.19, score=52.4]; PHD-finger [PF13831.8, score=36.5]; Jumonji domain-containing protein 2A Tudor domain [PF18104.3, score=34.5]; PHD-finger [PF00628.31, score=29.8]; PHD-like zinc-binding domain [PF13771.8, score=26.1]; Domain of unknown function (DUF4537) [PF15057.8, score=22.1]; DNA repair protein Crb2 Tudor domain [PF18115.3, score=18.9]} {Human: ENSG00000107077, KDM4C, lysine demethylase 4C, [RH, Score=479, Expect=5e-151]; ENSG00000066135, KDM4A, lysine demethylase 4A, [RH, Score=475, Expect=7e-147]; ENSG00000127663, KDM4B, lysine demethylase 4B, [RH, Score=462, Expect=4e-141]} {Mouse: ENSMUSG00000033326, Kdm4a, lysine (K)-specific demethylase 4A, [RH, Score=476, Expect=4e-147]; ENSMUSG00000028397, Kdm4c, lysine (K)-specific demethylase 4C, [RH, Score=473, Expect=4e-146]; ENSMUSG00000024201, Kdm4b, lysine (K)-specific demethylase 4B, [RH, Score=467, Expect=3e-144]} {Dmel: FBgn0053182, Kdm4B, Lysine (K)-specific demethylase 4B, [RH, Score=474, Expect=6e-151]} {Celegans: WBGene00012982, jmjd-2, Lysine-specific demethylase 4, [RH, Score=328, Expect=3e-95]} {Smed: dd_Smed_v6_10398_0_1, dd_Smed_v6_10398_0_1, [RH, Score=523, Expect=5e-167]} {RNA1509_11069, RNA1509_19042, RNA1509_37896, RNA1509_42721} {RNA1310_1204, RNA1509_11069, RNA1509_19042, RNA1509_37896, RNA1509_42721} {RNA1509_11069, RNA1509_19042, RNA1509_37896, RNA1509_42721, RNA815_6410}
3. MligTC455_18201 2066 43.04 Mlig455_012852

Neo: -

Age: logFC(26M/2M)=-0.426

TSGA10 1.729 - 0.748 - - 0.981 - Mlig455_012852 {REF} {Length: 3652} {TRANSSPLICED} {Pfam: Takusan [PF04822.15, score=19.1]} {Human: ENSG00000135951, TSGA10, testis specific 10, [Score=167, Expect=1e-42]; ENSG00000174799, CEP135, centrosomal protein 135, [Score=159, Expect=4e-39]} {Mouse: ENSMUSG00000036403, Cep135, centrosomal protein 135, [Score=163, Expect=1e-40]; ENSMUSG00000060771, Tsga10, testis specific 10, [Score=157, Expect=2e-39]} {Dmel: FBgn0036480, Cep135, Centrosomal protein 135kDa, [Score=51.2, Expect=5e-06]} {Smed: dd_Smed_v6_5218_0_1, dd_Smed_v6_5218_0_1, [Score=177, Expect=1e-45]} {RNA1509_8974} {RNA1310_4398.1, RNA1509_8974} {RNA1509_8974, RNA815_1443.1}
4. MligTC455_26501 549 11.43 Mlig455_067644

Neo: -

Age: Down-Down-Up

Region-enriched R2: 1.808/0.01808

DNAH10 1.663 - 0.704 - - 0.959 - Mlig455_067644 {REF} {Length: 5057} {Pfam: ATP-binding dynein motor region [PF12781.9, score=99.8]; Dynein heavy chain C-terminal domain [PF18199.3, score=96.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=37.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=18.4]} {Human: ENSG00000281935, DNAH10, dynein axonemal heavy chain 10, [Score=143, Expect=2e-33]; ENSG00000197653, DNAH10, dynein axonemal heavy chain 10, [Score=142, Expect=3e-33]} {Mouse: ENSMUSG00000033987, Dnah17, dynein, axonemal, heavy chain 17, [Score=136, Expect=2e-31]} {Dmel: FBgn0039510, CG3339, [Score=115, Expect=2e-25]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=60.5, Expect=1e-08]} {Smed: dd_Smed_v6_4113_0_1, dd_Smed_v6_4113_0_1, [Score=532, Expect=1e-159]} {RNA1509_2294} {RNA1310_872.1} {RNA815_291}
5. MligTC455_51694 477 9.94 Mlig455_042379

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.535

1.656 - - 0.703 0.953 - - Mlig455_042379 {REF} {Length: 484} {RNA1509_54355} {RNA1310_76708, RNA1509_54355} {RNA1509_54355, RNA815_43478}
6. MligTC455_32569 388 8.09 Mlig455_037270

Neo: -

Age: -

IRAK4 0.964 - - - - 0.964 - Mlig455_037270 {REF} {Length: 3195} {Pfam: Protein kinase domain [PF00069.27, score=132.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=110.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.4]} {Human: ENSG00000198001, IRAK4, interleukin 1 receptor associated kinase 4, [Score=78.6, Expect=1e-14]} {Mouse: ENSMUSG00000059883, Irak4, interleukin-1 receptor-associated kinase 4, [Score=82.4, Expect=5e-16]} {Dmel: FBgn0010441, pll, pelle, [Score=75.5, Expect=8e-14]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_9065_0_1, dd_Smed_v6_9065_0_1, [Score=67.8, Expect=4e-12]} {RNA1509_57751, RNA1509_59099} {RNA1310_29366, RNA1509_57751, RNA1509_59099} {RNA1509_57751, RNA1509_59099, RNA815_24983}
7. MligTC455_37310 188 3.92 Mlig455_043635

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=3.872

ARRDC4 0.964 - - - - 0.964 - Mlig455_043635 {REF} {Length: 2231} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.3]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=44.1]} {Human: ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=70.1, Expect=3e-12]; ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=67.8, Expect=2e-11]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=63.5, Expect=3e-10]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=78.2, Expect=2e-15]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.5, Expect=4e-11]} {RNA1509_13418} {RNA1310_36821} {RNA815_11006.1}
8. MligTC455_17592 62 1.28 Mlig455_003740

Neo: -

Age: -

Regeneration-downregulated R2: -3.050

Regeneration-depleted R2: -3.050

PCIF1 0.958 - - - - 0.958 - Mlig455_003740 {REF} {Length: 2838} {TRANSSPLICED} {Pfam: Phosphorylated CTD interacting factor 1 WW domain [PF12237.10, score=224.4]; WW domain [PF00397.28, score=40.5]} {Human: ENSG00000100982, PCIF1, PDX1 C-terminal inhibiting factor 1, [RH, Score=567, Expect=0.0]} {Mouse: ENSMUSG00000039849, Pcif1, PDX1 C-terminal inhibiting factor 1, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0037021, CG11399, [RH, Score=535, Expect=4e-179]} {Smed: dd_Smed_v6_9161_0_1, dd_Smed_v6_9161_0_1, [RH, Score=459, Expect=9e-153]} {RNA1509_12189} {RNA1310_4645} {RNA815_2873.1}
9. MligTC455_52876 2286 47.62 Mlig455_007967, Mlig455_015597

Neo: -

Age: -

Region-enriched R7: 1.185/0.00103

TXNDC5 0.958 - - - 0.958 - -

Mlig455_007967 {REF} {Length: 1591} {TRANSSPLICED} {Pfam: Thioredoxin [PF00085.22, score=168.5]; Thioredoxin-like domain [PF13098.8, score=33.4]; Thioredoxin-like [PF13899.8, score=28.2]; Thioredoxin-like [PF13905.8, score=23.2]; Hydrogenase-1 expression protein HyaE [PF07449.13, score=21.5]; F plasmid transfer operon protein [PF13728.8, score=20.3]; AhpC/TSA family [PF00578.23, score=20.0]; OST3 / OST6 family, transporter family [PF04756.15, score=19.7]} {Human: ENSG00000239264, TXNDC5, thioredoxin domain containing 5, [RH, Score=171, Expect=2e-49]} {Mouse: ENSMUSG00000038991, Txndc5, thioredoxin domain containing 5, [RH, Score=171, Expect=1e-49]} {Dmel: FBgn0030329, prtp, pretaporter, [RH, Score=148, Expect=7e-41]} {Celegans: WBGene00015752, C14B9.2, Probable protein disulfide-isomerase A4, [Score=113, Expect=5e-27]} {Smed: dd_Smed_v6_821_0_1, dd_Smed_v6_821_0_1, [Score=109, Expect=3e-26]} {RNA1509_40028} {RNA1310_10265} {RNA815_5310.1}

Mlig455_015597 {REF} {Length: 1598} {TRANSSPLICED} {Pfam: Thioredoxin [PF00085.22, score=168.5]; Thioredoxin-like domain [PF13098.8, score=33.4]; Thioredoxin-like [PF13899.8, score=28.2]; Thioredoxin-like [PF13905.8, score=23.2]; Hydrogenase-1 expression protein HyaE [PF07449.13, score=21.5]; F plasmid transfer operon protein [PF13728.8, score=20.3]; AhpC/TSA family [PF00578.23, score=20.0]; OST3 / OST6 family, transporter family [PF04756.15, score=19.7]} {Human: ENSG00000239264, TXNDC5, thioredoxin domain containing 5, [RH, Score=171, Expect=2e-49]} {Mouse: ENSMUSG00000038991, Txndc5, thioredoxin domain containing 5, [RH, Score=171, Expect=1e-49]} {Dmel: FBgn0030329, prtp, pretaporter, [RH, Score=148, Expect=7e-41]} {Celegans: WBGene00015752, C14B9.2, Probable protein disulfide-isomerase A4, [Score=113, Expect=5e-27]} {Smed: dd_Smed_v6_821_0_1, dd_Smed_v6_821_0_1, [Score=109, Expect=3e-26]} {RNA1509_40028} {RNA1310_10265} {RNA815_5310.1}
10. MligTC455_23570 81 1.68 Mlig455_013090

Neo: -

Age: Up-Down-Down

TIAM2 0.955 - - - - 0.955 - Mlig455_013090 {REF} {Length: 5714} {Pfam: RhoGEF domain [PF00621.22, score=80.6]; PH domain [PF00169.31, score=52.0]; T-lymphoma invasion and metastasis CC-Ex domain [PF18385.3, score=44.0]; Pleckstrin homology domain [PF15410.8, score=39.2]; PDZ domain [PF17820.3, score=30.4]; PDZ domain [PF00595.26, score=22.8]} {Human: ENSG00000146426, TIAM2, T cell lymphoma invasion and metastasis 2, [Score=246, Expect=2e-65]; ENSG00000156299, TIAM1, T cell lymphoma invasion and metastasis 1, [Score=242, Expect=5e-64]} {Mouse: ENSMUSG00000023800, Tiam2, T cell lymphoma invasion and metastasis 2, [Score=245, Expect=6e-65]; ENSMUSG00000002489, Tiam1, T cell lymphoma invasion and metastasis 1, [Score=242, Expect=1e-65]} {Dmel: FBgn0085447, sif, still life, [Score=258, Expect=9e-69]} {RNA1509_26471} {RNA1310_2308.1} {RNA815_4637}
11. MligTC455_26547 167 3.47 Mlig455_026852

Neo: -

Age: -

CSPP1 0.955 - - - - 0.955 - Mlig455_026852 {REF} {Length: 3986} {TRANSSPLICED} {Pfam: Mitochondrial ATPase inhibitor, IATP [PF04568.14, score=20.3]} {Human: ENSG00000104218, CSPP1, centrosome and spindle pole associated protein 1, [Score=82.8, Expect=3e-15]} {Mouse: ENSMUSG00000056763, Cspp1, centrosome and spindle pole associated protein 1, [Score=99.4, Expect=1e-20]} {Smed: dd_Smed_v6_13453_0_1, dd_Smed_v6_13453_0_1, [Score=87.8, Expect=2e-17]} {RNA1509_7480} {RNA1310_2740.1} {RNA815_13668}
12. MligTC455_29264 78 1.62 Mlig455_061707

Neo: -

Age: logFC(26M/2M)=1.238

0.954 - - - - 0.954 - Mlig455_061707 {REF} {Length: 5671} {Pfam: Zinc knuckle [PF00098.25, score=33.9]} {Celegans: WBGene00017210, F07E5.5, [Score=53.5, Expect=3e-07]} {RNA1509_12781} {RNA1310_541.1} {RNA815_23.1}
13. MligTC455_53021 248 5.17 Mlig455_039734, Mlig455_060892

Neo: -

Age: Down-Down-Up

0.953 - - - - 0.953 -

Mlig455_039734 {REF} {Length: 1487} {TRANSSPLICED} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}

Mlig455_060892 {REF} {Length: 3436} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}

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