Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_53094 | 2333 | 48.61 | Mlig455_002734, Mlig455_063350 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.745 Region-enriched R4: 2.207/0.00184 |
SOX2 | Mlig455_002734 {REF} {Length: 2479} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]; VIT family [PF01988.21, score=19.5]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=1e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=9e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352, RNA1509_11450} {RNA1509_11450, RNA815_15989} Mlig455_063350 {REF} {Length: 2568} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=2e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=1e-53]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1310_8352, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1509_19275, RNA1509_34805, RNA1509_47357, RNA815_15989} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -8.702 | 5.69 | 0.00034 | 0.06102 | |
RegionR2 | 1.031 | 5.69 | 0.15103 | 0.48542 | |
RegionR3 | 0.832 | 5.69 | 0.25339 | 0.79741 | |
RegionR4 | 2.207 | 5.69 | 0.00012 | 0.00184 | |
RegionR5 | 0.761 | 5.69 | 0.31252 | 0.65147 | |
RegionR6 | 1.523 | 5.69 | 0.00511 | 0.10991 | |
RegionR7 | 1.509 | 5.69 | 0.01165 | 0.18854 | |
RegionR8 | 0.839 | 5.69 | 0.32427 | 0.95723 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 7.978 | 5.69 | 0.01018 | 0.44761 | |
RegenerationR2 | -0.222 | 5.69 | 0.53634 | 0.88670 | |
RegenerationR3 | -0.158 | 5.69 | 0.67943 | 0.94012 | |
RegenerationR4 | -0.636 | 5.69 | 0.10718 | 0.50426 | |
RegenerationR5 | -0.032 | 5.69 | 0.93201 | 1.00000 | |
RegenerationR6 | -0.511 | 5.69 | 0.17776 | 0.51164 | |
RegenerationBL | 0.265 | 5.69 | 0.46306 | 0.82972 | |
RegenerationTP | -0.263 | 5.69 | 0.52278 | 0.91550 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_53094 | 2333 | 48.61 | Mlig455_002734, Mlig455_063350 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.745 Region-enriched R4: 2.207/0.00184 |
SOX2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_002734 {REF} {Length: 2479} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]; VIT family [PF01988.21, score=19.5]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=1e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=9e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352, RNA1509_11450} {RNA1509_11450, RNA815_15989} Mlig455_063350 {REF} {Length: 2568} {Pfam: HMG (high mobility group) box [PF00505.21, score=93.9]; HMG-box domain [PF09011.12, score=42.1]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=183, Expect=2e-53]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=183, Expect=1e-53]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=163, Expect=1e-43]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [RH, Score=177, Expect=4e-52]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=163, Expect=2e-44]} {RNA1509_11450, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1310_8352, RNA1509_19275, RNA1509_34805, RNA1509_47357} {RNA1509_19275, RNA1509_34805, RNA1509_47357, RNA815_15989} |
2. | MligTC455_19137 | 807 | 16.82 | Mlig455_067132 | Neo: Irradiation Age: - |
KDM4C | 1.764 | - | - | - | 0.961 | 0.803 | - | Mlig455_067132 {REF} {Length: 4923} {TRANSSPLICED} {Pfam: JmjC domain, hydroxylase [PF02373.24, score=145.4]; PHD-zinc-finger like domain [PF13832.8, score=57.1]; jmjN domain [PF02375.19, score=52.4]; PHD-finger [PF13831.8, score=36.5]; Jumonji domain-containing protein 2A Tudor domain [PF18104.3, score=34.5]; PHD-finger [PF00628.31, score=29.8]; PHD-like zinc-binding domain [PF13771.8, score=26.1]; Domain of unknown function (DUF4537) [PF15057.8, score=22.1]; DNA repair protein Crb2 Tudor domain [PF18115.3, score=18.9]} {Human: ENSG00000107077, KDM4C, lysine demethylase 4C, [RH, Score=479, Expect=5e-151]; ENSG00000066135, KDM4A, lysine demethylase 4A, [RH, Score=475, Expect=7e-147]; ENSG00000127663, KDM4B, lysine demethylase 4B, [RH, Score=462, Expect=4e-141]} {Mouse: ENSMUSG00000033326, Kdm4a, lysine (K)-specific demethylase 4A, [RH, Score=476, Expect=4e-147]; ENSMUSG00000028397, Kdm4c, lysine (K)-specific demethylase 4C, [RH, Score=473, Expect=4e-146]; ENSMUSG00000024201, Kdm4b, lysine (K)-specific demethylase 4B, [RH, Score=467, Expect=3e-144]} {Dmel: FBgn0053182, Kdm4B, Lysine (K)-specific demethylase 4B, [RH, Score=474, Expect=6e-151]} {Celegans: WBGene00012982, jmjd-2, Lysine-specific demethylase 4, [RH, Score=328, Expect=3e-95]} {Smed: dd_Smed_v6_10398_0_1, dd_Smed_v6_10398_0_1, [RH, Score=523, Expect=5e-167]} {RNA1509_11069, RNA1509_19042, RNA1509_37896, RNA1509_42721} {RNA1310_1204, RNA1509_11069, RNA1509_19042, RNA1509_37896, RNA1509_42721} {RNA1509_11069, RNA1509_19042, RNA1509_37896, RNA1509_42721, RNA815_6410} |
3. | MligTC455_18201 | 2066 | 43.04 | Mlig455_012852 | Neo: - Age: logFC(26M/2M)=-0.426 |
TSGA10 | 1.729 | - | 0.748 | - | - | 0.981 | - | Mlig455_012852 {REF} {Length: 3652} {TRANSSPLICED} {Pfam: Takusan [PF04822.15, score=19.1]} {Human: ENSG00000135951, TSGA10, testis specific 10, [Score=167, Expect=1e-42]; ENSG00000174799, CEP135, centrosomal protein 135, [Score=159, Expect=4e-39]} {Mouse: ENSMUSG00000036403, Cep135, centrosomal protein 135, [Score=163, Expect=1e-40]; ENSMUSG00000060771, Tsga10, testis specific 10, [Score=157, Expect=2e-39]} {Dmel: FBgn0036480, Cep135, Centrosomal protein 135kDa, [Score=51.2, Expect=5e-06]} {Smed: dd_Smed_v6_5218_0_1, dd_Smed_v6_5218_0_1, [Score=177, Expect=1e-45]} {RNA1509_8974} {RNA1310_4398.1, RNA1509_8974} {RNA1509_8974, RNA815_1443.1} |
4. | MligTC455_26501 | 549 | 11.43 | Mlig455_067644 | Neo: - Age: Down-Down-Up Region-enriched R2: 1.808/0.01808 |
DNAH10 | 1.663 | - | 0.704 | - | - | 0.959 | - | Mlig455_067644 {REF} {Length: 5057} {Pfam: ATP-binding dynein motor region [PF12781.9, score=99.8]; Dynein heavy chain C-terminal domain [PF18199.3, score=96.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=37.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=18.4]} {Human: ENSG00000281935, DNAH10, dynein axonemal heavy chain 10, [Score=143, Expect=2e-33]; ENSG00000197653, DNAH10, dynein axonemal heavy chain 10, [Score=142, Expect=3e-33]} {Mouse: ENSMUSG00000033987, Dnah17, dynein, axonemal, heavy chain 17, [Score=136, Expect=2e-31]} {Dmel: FBgn0039510, CG3339, [Score=115, Expect=2e-25]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=60.5, Expect=1e-08]} {Smed: dd_Smed_v6_4113_0_1, dd_Smed_v6_4113_0_1, [Score=532, Expect=1e-159]} {RNA1509_2294} {RNA1310_872.1} {RNA815_291} |
5. | MligTC455_51694 | 477 | 9.94 | Mlig455_042379 | Neo: - |
1.656 | - | - | 0.703 | 0.953 | - | - | Mlig455_042379 {REF} {Length: 484} {RNA1509_54355} {RNA1310_76708, RNA1509_54355} {RNA1509_54355, RNA815_43478} | |
6. | MligTC455_32569 | 388 | 8.09 | Mlig455_037270 | Neo: - Age: - |
IRAK4 | 0.964 | - | - | - | - | 0.964 | - | Mlig455_037270 {REF} {Length: 3195} {Pfam: Protein kinase domain [PF00069.27, score=132.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=110.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.4]} {Human: ENSG00000198001, IRAK4, interleukin 1 receptor associated kinase 4, [Score=78.6, Expect=1e-14]} {Mouse: ENSMUSG00000059883, Irak4, interleukin-1 receptor-associated kinase 4, [Score=82.4, Expect=5e-16]} {Dmel: FBgn0010441, pll, pelle, [Score=75.5, Expect=8e-14]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_9065_0_1, dd_Smed_v6_9065_0_1, [Score=67.8, Expect=4e-12]} {RNA1509_57751, RNA1509_59099} {RNA1310_29366, RNA1509_57751, RNA1509_59099} {RNA1509_57751, RNA1509_59099, RNA815_24983} |
7. | MligTC455_37310 | 188 | 3.92 | Mlig455_043635 | Neo: - |
ARRDC4 | 0.964 | - | - | - | - | 0.964 | - | Mlig455_043635 {REF} {Length: 2231} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.3]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=44.1]} {Human: ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=70.1, Expect=3e-12]; ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=67.8, Expect=2e-11]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=63.5, Expect=3e-10]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=78.2, Expect=2e-15]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.5, Expect=4e-11]} {RNA1509_13418} {RNA1310_36821} {RNA815_11006.1} |
8. | MligTC455_17592 | 62 | 1.28 | Mlig455_003740 | Neo: - Age: - Regeneration-downregulated R2: -3.050 Regeneration-depleted R2: -3.050 |
PCIF1 | 0.958 | - | - | - | - | 0.958 | - | Mlig455_003740 {REF} {Length: 2838} {TRANSSPLICED} {Pfam: Phosphorylated CTD interacting factor 1 WW domain [PF12237.10, score=224.4]; WW domain [PF00397.28, score=40.5]} {Human: ENSG00000100982, PCIF1, PDX1 C-terminal inhibiting factor 1, [RH, Score=567, Expect=0.0]} {Mouse: ENSMUSG00000039849, Pcif1, PDX1 C-terminal inhibiting factor 1, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0037021, CG11399, [RH, Score=535, Expect=4e-179]} {Smed: dd_Smed_v6_9161_0_1, dd_Smed_v6_9161_0_1, [RH, Score=459, Expect=9e-153]} {RNA1509_12189} {RNA1310_4645} {RNA815_2873.1} |
9. | MligTC455_52876 | 2286 | 47.62 | Mlig455_007967, Mlig455_015597 | Neo: - Age: - Region-enriched R7: 1.185/0.00103 |
TXNDC5 | 0.958 | - | - | - | 0.958 | - | - | Mlig455_007967 {REF} {Length: 1591} {TRANSSPLICED} {Pfam: Thioredoxin [PF00085.22, score=168.5]; Thioredoxin-like domain [PF13098.8, score=33.4]; Thioredoxin-like [PF13899.8, score=28.2]; Thioredoxin-like [PF13905.8, score=23.2]; Hydrogenase-1 expression protein HyaE [PF07449.13, score=21.5]; F plasmid transfer operon protein [PF13728.8, score=20.3]; AhpC/TSA family [PF00578.23, score=20.0]; OST3 / OST6 family, transporter family [PF04756.15, score=19.7]} {Human: ENSG00000239264, TXNDC5, thioredoxin domain containing 5, [RH, Score=171, Expect=2e-49]} {Mouse: ENSMUSG00000038991, Txndc5, thioredoxin domain containing 5, [RH, Score=171, Expect=1e-49]} {Dmel: FBgn0030329, prtp, pretaporter, [RH, Score=148, Expect=7e-41]} {Celegans: WBGene00015752, C14B9.2, Probable protein disulfide-isomerase A4, [Score=113, Expect=5e-27]} {Smed: dd_Smed_v6_821_0_1, dd_Smed_v6_821_0_1, [Score=109, Expect=3e-26]} {RNA1509_40028} {RNA1310_10265} {RNA815_5310.1} Mlig455_015597 {REF} {Length: 1598} {TRANSSPLICED} {Pfam: Thioredoxin [PF00085.22, score=168.5]; Thioredoxin-like domain [PF13098.8, score=33.4]; Thioredoxin-like [PF13899.8, score=28.2]; Thioredoxin-like [PF13905.8, score=23.2]; Hydrogenase-1 expression protein HyaE [PF07449.13, score=21.5]; F plasmid transfer operon protein [PF13728.8, score=20.3]; AhpC/TSA family [PF00578.23, score=20.0]; OST3 / OST6 family, transporter family [PF04756.15, score=19.7]} {Human: ENSG00000239264, TXNDC5, thioredoxin domain containing 5, [RH, Score=171, Expect=2e-49]} {Mouse: ENSMUSG00000038991, Txndc5, thioredoxin domain containing 5, [RH, Score=171, Expect=1e-49]} {Dmel: FBgn0030329, prtp, pretaporter, [RH, Score=148, Expect=7e-41]} {Celegans: WBGene00015752, C14B9.2, Probable protein disulfide-isomerase A4, [Score=113, Expect=5e-27]} {Smed: dd_Smed_v6_821_0_1, dd_Smed_v6_821_0_1, [Score=109, Expect=3e-26]} {RNA1509_40028} {RNA1310_10265} {RNA815_5310.1} |
10. | MligTC455_23570 | 81 | 1.68 | Mlig455_013090 | Neo: - Age: Up-Down-Down |
TIAM2 | 0.955 | - | - | - | - | 0.955 | - | Mlig455_013090 {REF} {Length: 5714} {Pfam: RhoGEF domain [PF00621.22, score=80.6]; PH domain [PF00169.31, score=52.0]; T-lymphoma invasion and metastasis CC-Ex domain [PF18385.3, score=44.0]; Pleckstrin homology domain [PF15410.8, score=39.2]; PDZ domain [PF17820.3, score=30.4]; PDZ domain [PF00595.26, score=22.8]} {Human: ENSG00000146426, TIAM2, T cell lymphoma invasion and metastasis 2, [Score=246, Expect=2e-65]; ENSG00000156299, TIAM1, T cell lymphoma invasion and metastasis 1, [Score=242, Expect=5e-64]} {Mouse: ENSMUSG00000023800, Tiam2, T cell lymphoma invasion and metastasis 2, [Score=245, Expect=6e-65]; ENSMUSG00000002489, Tiam1, T cell lymphoma invasion and metastasis 1, [Score=242, Expect=1e-65]} {Dmel: FBgn0085447, sif, still life, [Score=258, Expect=9e-69]} {RNA1509_26471} {RNA1310_2308.1} {RNA815_4637} |
11. | MligTC455_26547 | 167 | 3.47 | Mlig455_026852 | Neo: - Age: - |
CSPP1 | 0.955 | - | - | - | - | 0.955 | - | Mlig455_026852 {REF} {Length: 3986} {TRANSSPLICED} {Pfam: Mitochondrial ATPase inhibitor, IATP [PF04568.14, score=20.3]} {Human: ENSG00000104218, CSPP1, centrosome and spindle pole associated protein 1, [Score=82.8, Expect=3e-15]} {Mouse: ENSMUSG00000056763, Cspp1, centrosome and spindle pole associated protein 1, [Score=99.4, Expect=1e-20]} {Smed: dd_Smed_v6_13453_0_1, dd_Smed_v6_13453_0_1, [Score=87.8, Expect=2e-17]} {RNA1509_7480} {RNA1310_2740.1} {RNA815_13668} |
12. | MligTC455_29264 | 78 | 1.62 | Mlig455_061707 | Neo: - Age: logFC(26M/2M)=1.238 |
0.954 | - | - | - | - | 0.954 | - | Mlig455_061707 {REF} {Length: 5671} {Pfam: Zinc knuckle [PF00098.25, score=33.9]} {Celegans: WBGene00017210, F07E5.5, [Score=53.5, Expect=3e-07]} {RNA1509_12781} {RNA1310_541.1} {RNA815_23.1} | |
13. | MligTC455_53021 | 248 | 5.17 | Mlig455_039734, Mlig455_060892 | Neo: - Age: Down-Down-Up |
0.953 | - | - | - | - | 0.953 | - | Mlig455_039734 {REF} {Length: 1487} {TRANSSPLICED} {RNA1509_24093} {RNA1310_26642} {RNA815_14301} Mlig455_060892 {REF} {Length: 3436} {RNA1509_24093} {RNA1310_26642} {RNA815_14301} |