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Results for MligTC455_19022

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_19022 687 14.31 Mlig455_037405

Neo: -

Age: -

Region-enriched R3: 1.615/0.00300
Region-enriched R5: 1.137/0.02464

GRINA Mlig455_037405 {REF} {Length: 2190} {Pfam: Inhibitor of apoptosis-promoting Bax1 [PF01027.22, score=72.3]} {Human: ENSG00000178719, GRINA, glutamate ionotropic receptor NMDA type subunit associated protein 1, [Score=163, Expect=3e-47]} {Mouse: ENSMUSG00000022564, Grina, glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding), [Score=145, Expect=4e-41]; ENSMUSG00000023011, Faim2, Fas apoptotic inhibitory molecule 2, [Score=144, Expect=8e-41]} {Dmel: FBgn0013305, Nmda1, N-methyl-D-aspartate receptor-associated protein, [Score=155, Expect=6e-45]} {Celegans: WBGene00006470, tag-120, [Score=111, Expect=4e-29]} {Smed: dd_Smed_v6_1586_0_1, dd_Smed_v6_1586_0_1, [Score=171, Expect=9e-52]} {RNA1509_32288} {RNA1310_27497.1, RNA1509_32288} {RNA1509_32288, RNA815_12093}

Cumulative graph for MligTC455_19022

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.718 4.153 0.55513 1.00000
RegionR2 -1.081 4.153 0.08153 0.34989
RegionR3 1.615 4.153 0.00006 0.00300
RegionR4 0.809 4.153 0.08620 0.27854
RegionR5 1.137 4.153 0.00317 0.02464
RegionR6 0.543 4.153 0.24201 0.82745
RegionR7 -1.773 4.153 0.01860 0.25126
RegionR8 -0.532 4.153 0.49687 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.445 4.153 0.80516 1.00000
RegenerationR2 0.032 4.153 0.95299 1.00000
RegenerationR3 -0.097 4.153 0.83483 0.99230
RegenerationR4 0.407 4.153 0.39826 0.81232
RegenerationR5 -0.093 4.153 0.83225 0.99828
RegenerationR6 0.272 4.153 0.57803 0.85660
RegenerationBL 0.612 4.153 0.32893 0.69505
RegenerationTP 0.005 4.153 0.99370 1.00000


Genes with expression patterns similar to MligTC455_19022

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_19022 687 14.31 Mlig455_037405

Neo: -

Age: -

Region-enriched R3: 1.615/0.00300
Region-enriched R5: 1.137/0.02464

GRINA 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_037405 {REF} {Length: 2190} {Pfam: Inhibitor of apoptosis-promoting Bax1 [PF01027.22, score=72.3]} {Human: ENSG00000178719, GRINA, glutamate ionotropic receptor NMDA type subunit associated protein 1, [Score=163, Expect=3e-47]} {Mouse: ENSMUSG00000022564, Grina, glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding), [Score=145, Expect=4e-41]; ENSMUSG00000023011, Faim2, Fas apoptotic inhibitory molecule 2, [Score=144, Expect=8e-41]} {Dmel: FBgn0013305, Nmda1, N-methyl-D-aspartate receptor-associated protein, [Score=155, Expect=6e-45]} {Celegans: WBGene00006470, tag-120, [Score=111, Expect=4e-29]} {Smed: dd_Smed_v6_1586_0_1, dd_Smed_v6_1586_0_1, [Score=171, Expect=9e-52]} {RNA1509_32288} {RNA1310_27497.1, RNA1509_32288} {RNA1509_32288, RNA815_12093}
2. MligTC455_20725 2475 51.57 Mlig455_035227

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.822

Region-enriched R3: 2.240/0.00003

SLC1A6 4.359 0.848 0.752 - 0.965 0.852 0.942 Mlig455_035227 {REF} {Length: 2154} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=2e-157]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=456, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=1e-153]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=3e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=422, Expect=3e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=422, Expect=8e-144]} {RNA1509_7401} {RNA1310_8553.1, RNA1509_7401} {RNA1509_7401, RNA815_2974.1}
3. MligTC455_53810 10368 216.01 Mlig455_015254

Neo: -

Age: logFC(26M/2M)=-0.519

Region-enriched R3: 1.584/0.00569
Region-enriched R5: 1.232/0.02515

SULT1C4 4.093 0.879 0.772 - 0.953 0.782 0.707 Mlig455_015254 {REF} {Length: 3712} {Pfam: Sulfotransferase domain [PF00685.29, score=172.2]; Sulfotransferase family [PF13469.8, score=31.5]} {Human: ENSG00000198075, SULT1C4, sulfotransferase family 1C member 4, [Score=168, Expect=6e-50]; ENSG00000198203, SULT1C2, sulfotransferase family 1C member 2, [Score=167, Expect=7e-50]} {Mouse: ENSMUSG00000023122, Sult1c2, sulfotransferase family, cytosolic, 1C, member 2, [Score=163, Expect=3e-48]} {Dmel: FBgn0034887, St1, Sulfotransferase 1, [Score=111, Expect=2e-28]} {Celegans: WBGene00013748, ssu-1, Suppressor of Stomatin mutant Uncoordination, [Score=99.0, Expect=2e-23]} {Smed: dd_Smed_v6_4622_0_1, dd_Smed_v6_4622_0_1, [Score=152, Expect=1e-44]} {RNA1509_178, RNA1509_182} {RNA1310_14124, RNA1509_178, RNA1509_182} {RNA1509_178, RNA1509_182, RNA815_6793}
4. MligTC455_40682 2549 53.1 Mlig455_013284, Mlig455_035928

Neo: -

Age: -

Region-enriched R3: 1.724/0.00155
Region-enriched R4: 1.452/0.02174
Region-enriched R5: 1.104/0.04518

3.588 0.809 - - 0.958 0.890 0.931

Mlig455_013284 {REF} {Length: 2073} {Pfam: Tctex-1 family [PF03645.15, score=31.9]} {Mouse: ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=50.1, Expect=3e-07]; ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=50.1, Expect=3e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=57.8, Expect=2e-10]} {RNA1509_11021, RNA1509_22678} {RNA1310_29221, RNA1509_11021, RNA1509_22678} {RNA1509_11021, RNA1509_22678, RNA815_16910}

Mlig455_035928 {REF} {Length: 1424} {Pfam: Tctex-1 family [PF03645.15, score=31.7]} {Mouse: ENSMUSG00000079707, Tcte3, t-complex-associated testis expressed 3, [Score=49.7, Expect=4e-07]; ENSMUSG00000079710, Gm3448, predicted gene 3448, [Score=49.7, Expect=4e-07]; ENSMUSG00000116780, Gm3417, predicted gene 3417, [Score=48.5, Expect=9e-07]} {Smed: dd_Smed_v6_12108_0_1, dd_Smed_v6_12108_0_1, [Score=58.5, Expect=1e-10]} {RNA1509_11021, RNA1509_38233} {RNA1310_29221, RNA1509_38233} {RNA1509_38233, RNA815_16910}
5. MligTC455_26178 362 7.54 Mlig455_016066

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.817

Region-enriched R4: 2.312/0.03652
Region-enriched R3: 2.220/0.04325

3.585 0.865 - - 0.924 0.842 0.954 Mlig455_016066 {REF} {Length: 1028} {RNA1509_21892} {RNA1310_19861} {RNA815_9448.1}
6. MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

3.519 0.816 - - 0.902 0.841 0.960

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}
7. MligTC455_20726 1772 36.91 Mlig455_035274

Neo: -

Age: -

Region-enriched R3: 2.119/0.00009

SLC1A6 3.517 0.723 - - 0.966 0.873 0.955 Mlig455_035274 {REF} {Length: 2086} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=9e-158]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=457, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=6e-154]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=4e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=421, Expect=6e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=427, Expect=2e-145]} {RNA1509_5272, RNA1509_57758, RNA1509_7401} {RNA1310_8553.1, RNA1509_5272, RNA1509_57758} {RNA1509_5272, RNA1509_57758, RNA815_2974.1}
8. MligTC455_42150 1601 33.36 Mlig455_031740

Neo: -

Age: -

Region-enriched R3: 1.735/0.01830

3.357 - - 0.722 0.959 0.886 0.790 Mlig455_031740 {REF} {Length: 2276} {Pfam: Lectin C-type domain [PF00059.23, score=29.1]} {Celegans: WBGene00016619, C43H6.6, [Score=48.9, Expect=5e-06]} {RNA1509_9329} {RNA1310_19331.2} {RNA815_8190.1}
9. MligTC455_46262 2748 57.25 Mlig455_010182, Mlig455_058667

Neo: -

Age: logFC(26M/2M)=0.747

RETSAT 3.283 - - 0.722 0.876 0.716 0.969

Mlig455_010182 {REF} {Length: 7403} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=65.4]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=57.3]; FAD binding domain [PF00890.26, score=39.3]; FAD dependent oxidoreductase [PF12831.9, score=28.5]; FAD dependent oxidoreductase [PF01266.26, score=28.2]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.1]; Thi4 family [PF01946.19, score=20.6]; FAD binding domain [PF01494.21, score=20.5]; MCRA family [PF06100.13, score=18.0]} {Human: ENSG00000042445, RETSAT, retinol saturase, [RH, Score=393, Expect=8e-129]} {Mouse: ENSMUSG00000056666, Retsat, retinol saturase (all trans retinol 13,14 reductase), [Score=414, Expect=5e-137]} {RNA1509_1340} {RNA1310_6908.1} {RNA815_3307}

Mlig455_058667 {REF} {Length: 2407} {Pfam: NAD(P)-binding Rossmann-like domain [PF13450.8, score=57.5]; Flavin containing amine oxidoreductase [PF01593.26, score=47.8]; FAD binding domain [PF00890.26, score=36.0]; FAD dependent oxidoreductase [PF12831.9, score=34.2]; FAD dependent oxidoreductase [PF01266.26, score=30.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=25.9]; Thi4 family [PF01946.19, score=20.7]; FAD binding domain [PF01494.21, score=20.6]; MCRA family [PF06100.13, score=18.2]} {Human: ENSG00000042445, RETSAT, retinol saturase, [Score=300, Expect=2e-93]} {Mouse: ENSMUSG00000056666, Retsat, retinol saturase (all trans retinol 13,14 reductase), [Score=318, Expect=6e-101]} {RNA1509_1340} {RNA1310_6908.1} {RNA815_3307}
10. MligTC455_27869 8765 182.6 Mlig455_051857, Mlig455_051868, Mlig455_051893

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.214/0.00040
Region-enriched R5: 1.603/0.01133

ANPEP 3.274 0.750 - - 0.771 0.791 0.962

Mlig455_051857 {REF} {Length: 3680} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=238.0]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=560, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=546, Expect=6e-179]} {Dmel: FBgn0039640, CG14516, [RH, Score=536, Expect=1e-174]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=599, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051868 {REF} {Length: 4344} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=259.5]; Peptidase family M1 domain [PF01433.22, score=234.1]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=552, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=542, Expect=4e-177]} {Dmel: FBgn0039640, CG14516, [RH, Score=529, Expect=7e-172]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=406, Expect=1e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=595, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051893 {REF} {Length: 4373} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=236.2]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=558, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=545, Expect=3e-178]} {Dmel: FBgn0039640, CG14516, [RH, Score=533, Expect=2e-173]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=596, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}
11. MligTC455_37238 1196 24.92 Mlig455_049614

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.981

Region-enriched R3: 1.482/0.00582

PANK4 3.254 0.786 - 0.763 0.959 0.746 - Mlig455_049614 {REF} {Length: 1474} {Pfam: Fumble [PF03630.16, score=119.6]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=104, Expect=9e-24]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=104, Expect=9e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=95.9, Expect=4e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=65.1, Expect=3e-11]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=173, Expect=7e-51]} {RNA1509_8444} {RNA1310_20224, RNA1509_8444} {RNA1509_8444, RNA815_7673}
12. MligTC455_49468 3574 74.46 Mlig455_015846, Mlig455_016064

Neo: -

Age: logFC(26M/2M)=0.226

Region-enriched R3: 1.620/0.01404

SRR 2.732 0.853 - - 0.962 0.917 -

Mlig455_015846 {REF} {Length: 2263} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=269.4]; ACT domain [PF01842.27, score=26.5]} {Human: ENSG00000167720, SRR, serine racemase, [Score=169, Expect=3e-47]} {Mouse: ENSMUSG00000001323, Srr, serine racemase, [Score=139, Expect=9e-37]} {Dmel: FBgn0037684, CG8129, [RH, Score=469, Expect=3e-162]} {Celegans: WBGene00010456, K01C8.1, [RH, Score=484, Expect=8e-168]} {Smed: dd_Smed_v6_6737_0_1, dd_Smed_v6_6737_0_1, [Score=555, Expect=0.0]} {RNA1509_3329} {RNA1310_12273.1} {RNA815_4112.1}

Mlig455_016064 {REF} {Length: 2342} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=269.6]; ACT domain [PF01842.27, score=26.5]} {Human: ENSG00000167720, SRR, serine racemase, [Score=167, Expect=6e-47]} {Mouse: ENSMUSG00000001323, Srr, serine racemase, [Score=139, Expect=2e-36]} {Dmel: FBgn0037684, CG8129, [RH, Score=468, Expect=7e-162]} {Celegans: WBGene00010456, K01C8.1, [RH, Score=486, Expect=1e-168]} {Smed: dd_Smed_v6_6737_0_1, dd_Smed_v6_6737_0_1, [Score=558, Expect=0.0]} {RNA1509_3329} {RNA1310_12273.1, RNA1509_3329} {RNA1509_3329, RNA815_4112.1}
13. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 2.691 0.902 - - 0.955 0.834 -

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
14. MligTC455_19955 2064 42.99 Mlig455_014277, Mlig455_014328

Neo: -

Age: -

Region-enriched R4: 1.732/0.00087
Region-enriched R5: 1.027/0.01771

PHYHD1 2.678 0.855 - - 0.958 0.865 -

Mlig455_014277 {REF} {Length: 1311} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=178.4]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=238, Expect=3e-77]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=232, Expect=1e-74]} {Dmel: FBgn0037819, CG14688, [RH, Score=205, Expect=1e-64]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [RH, Score=220, Expect=1e-70]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [RH, Score=249, Expect=7e-82]} {RNA1509_18487} {RNA1310_28843.1} {RNA815_12227}

Mlig455_014328 {REF} {Length: 1306} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=178.5]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=239, Expect=2e-77]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=233, Expect=6e-75]} {Dmel: FBgn0037819, CG14688, [RH, Score=204, Expect=2e-64]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [RH, Score=218, Expect=9e-70]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [RH, Score=248, Expect=1e-81]} {RNA1509_18487} {RNA1310_28843.1} {RNA815_12227}
15. MligTC455_46260 1736 36.16 Mlig455_058605

Neo: -

Age: -

Region-enriched R3: 1.241/0.00018

Regeneration-upregulated R5: 1.429

Regeneration-enriched R5: 1.429

RETSAT 2.664 0.740 - - 0.933 - 0.991 Mlig455_058605 {REF} {Length: 5100} {Pfam: Sulfate permease family [PF00916.22, score=276.8]; STAS domain [PF01740.23, score=87.9]; Flavin containing amine oxidoreductase [PF01593.26, score=62.3]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=57.4]; FAD binding domain [PF00890.26, score=37.1]; FAD dependent oxidoreductase [PF12831.9, score=25.7]; FAD dependent oxidoreductase [PF01266.26, score=24.9]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=24.6]; STAS domain [PF13466.8, score=24.6]; Thi4 family [PF01946.19, score=19.7]; FAD binding domain [PF01494.21, score=19.3]} {Human: ENSG00000042445, RETSAT, retinol saturase, [Score=382, Expect=7e-118]} {Mouse: ENSMUSG00000056666, Retsat, retinol saturase (all trans retinol 13,14 reductase), [Score=401, Expect=3e-125]} {Dmel: FBgn0036770, Prestin, [Score=296, Expect=1e-85]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=308, Expect=2e-91]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [Score=360, Expect=2e-108]} {RNA1509_1340} {RNA1310_6908.1} {RNA815_3307}
16. MligTC455_16824 1812 37.75 Mlig455_003697, Mlig455_003738, Mlig455_003903

Neo: -

Age: Up-Down-Down

SMPD1 2.663 - - - 0.820 0.864 0.979

Mlig455_003697 {REF} {Length: 1645} {Pfam: Acid sphingomyelin phosphodiesterase C-terminal region [PF19272.1, score=20.8]; PAN domain [PF00024.28, score=18.8]} {Human: ENSG00000166311, SMPD1, sphingomyelin phosphodiesterase 1, [Score=73.6, Expect=4e-13]} {Mouse: ENSMUSG00000037049, Smpd1, sphingomyelin phosphodiesterase 1, acid lysosomal, [Score=68.2, Expect=1e-11]} {Dmel: FBgn0034997, CG3376, [Score=55.8, Expect=7e-08]} {Celegans: WBGene00000213, asm-3, Putative sphingomyelin phosphodiesterase asm-3, [Score=53.5, Expect=3e-07]} {Smed: dd_Smed_v6_38541_0_1, dd_Smed_v6_38541_0_1, [Score=65.9, Expect=5e-12]} {RNA1509_5998} {RNA1310_33480} {RNA815_17816.1}

Mlig455_003738 {REF} {Length: 2484} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=90.8]; Acid sphingomyelin phosphodiesterase C-terminal region [PF19272.1, score=40.9]} {Human: ENSG00000166311, SMPD1, sphingomyelin phosphodiesterase 1, [RH, Score=376, Expect=1e-122]} {Mouse: ENSMUSG00000037049, Smpd1, sphingomyelin phosphodiesterase 1, acid lysosomal, [RH, Score=374, Expect=6e-122]} {Dmel: FBgn0034997, CG3376, [Score=361, Expect=2e-116]} {Celegans: WBGene00000213, asm-3, Putative sphingomyelin phosphodiesterase asm-3, [RH, Score=340, Expect=8e-110]} {Smed: dd_Smed_v6_15691_0_1, dd_Smed_v6_15691_0_1, [Score=71.2, Expect=6e-13]} {RNA1509_5998} {RNA1310_9448} {RNA815_4533}

Mlig455_003903 {REF} {Length: 2345} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=89.9]; Acid sphingomyelin phosphodiesterase C-terminal region [PF19272.1, score=40.5]} {Human: ENSG00000166311, SMPD1, sphingomyelin phosphodiesterase 1, [RH, Score=379, Expect=5e-124]} {Mouse: ENSMUSG00000037049, Smpd1, sphingomyelin phosphodiesterase 1, acid lysosomal, [RH, Score=377, Expect=4e-123]} {Dmel: FBgn0034997, CG3376, [RH, Score=367, Expect=9e-118]} {Celegans: WBGene00000213, asm-3, Putative sphingomyelin phosphodiesterase asm-3, [RH, Score=338, Expect=5e-109]} {Smed: dd_Smed_v6_15691_0_1, dd_Smed_v6_15691_0_1, [Score=65.1, Expect=5e-11]} {RNA1509_5998} {RNA1310_9448, RNA1509_5998} {RNA1509_5998, RNA815_4533}
17. MligTC455_37114 9548 198.91 Mlig455_020763

Neo: -

Age: -

Region-enriched R3: 1.051/0.01206

LGMN 2.65 0.894 0.792 - 0.964 - - Mlig455_020763 {REF} {Length: 1971} {Pfam: Peptidase C13 family [PF01650.20, score=360.1]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=386, Expect=4e-131]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=391, Expect=4e-133]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=126, Expect=2e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=323, Expect=2e-106]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=104, Expect=5e-25]} {RNA1509_4583} {RNA1310_13933, RNA1509_4583} {RNA1509_4583, RNA815_6243.1}
18. MligTC455_45742 2132 44.42 Mlig455_003184, Mlig455_003387

Neo: -

Age: logFC(26M/2M)=0.345

Region-specific R4: 3.405
Region-specific R3: 3.388

Region-enriched R4: 3.484/0.00000
Region-enriched R3: 2.393/0.00000
Region-enriched R5: 1.235/0.00412

SLC22A4, SLC22A5 2.648 0.757 - - 0.936 - 0.955

Mlig455_003184 {REF} {Length: 2170} {Pfam: Sugar (and other) transporter [PF00083.26, score=102.2]; Major Facilitator Superfamily [PF07690.18, score=60.9]} {Human: ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=274, Expect=4e-84]; ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=274, Expect=7e-84]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=278, Expect=1e-85]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=285, Expect=2e-88]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=240, Expect=4e-71]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=198, Expect=7e-56]} {RNA1509_40645} {RNA1310_12725.1} {RNA815_4270}

Mlig455_003387 {REF} {Length: 2455} {Pfam: Sugar (and other) transporter [PF00083.26, score=70.5]; Major Facilitator Superfamily [PF07690.18, score=57.3]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=154, Expect=6e-42]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=147, Expect=2e-39]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=154, Expect=6e-42]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=174, Expect=1e-49]} {Celegans: WBGene00003843, oct-2, Organic Cation Transporter; Organic cation transporter, [Score=113, Expect=2e-27]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=116, Expect=1e-28]} {RNA1509_11765, RNA1509_40645} {RNA1310_12725.1, RNA1509_11765} {RNA1509_11765, RNA815_4270}
19. MligTC455_20464 3164 65.93 Mlig455_036496, Mlig455_056384

Neo: -

Age: -

Region-enriched R3: 1.967/0.00269
Region-enriched R4: 1.871/0.00861

RAB35 2.64 0.867 - - 0.951 - 0.822

Mlig455_036496 {REF} {Length: 1520} {Pfam: Ras family [PF00071.24, score=127.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=49.9]; RsgA GTPase [PF03193.18, score=37.9]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=20.9]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.1]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=5e-28]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=8e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=8e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=146, Expect=4e-44]} {RNA1509_21258} {RNA1310_21310.1} {RNA815_8782.1}

Mlig455_056384 {REF} {Length: 1510} {Pfam: Ras family [PF00071.24, score=127.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=51.7]; RsgA GTPase [PF03193.18, score=37.8]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=21.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.6]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=4e-28]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=105, Expect=2e-27]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=6e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=7e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=147, Expect=4e-44]} {RNA1509_12602, RNA1509_21258} {RNA1310_21310.1, RNA1509_12602, RNA1509_21258} {RNA1509_12602, RNA1509_21258, RNA815_8782.1}
20. MligTC455_43587 981 20.44 Mlig455_064849

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.445

Region-enriched R4: 1.141/0.04839

2.606 - 0.852 - 0.952 0.802 - Mlig455_064849 {REF} {Length: 1597} {RNA1509_13829} {RNA1310_22619, RNA1509_13829} {RNA1509_13829, RNA815_12635}
21. MligTC455_37974 443 9.23 Mlig455_055280

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.262

Region-enriched R4: 3.613/0.00002
Region-enriched R5: 2.322/0.00164

ASAH1 2.602 - - - 0.955 0.785 0.862 Mlig455_055280 {REF} {Length: 1484} {TRANSSPLICED} {Pfam: Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=83.9]; beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]} {Human: ENSG00000104763, ASAH1, N-acylsphingosine amidohydrolase 1, [Score=358, Expect=4e-121]} {Mouse: ENSMUSG00000031591, Asah1, N-acylsphingosine amidohydrolase 1, [Score=350, Expect=1e-118]} {Celegans: WBGene00010769, asah-1, Acid ceramidase, [Score=281, Expect=2e-91]} {RNA1509_14520, RNA1509_40978} {RNA1310_24069.2, RNA1509_14520, RNA1509_40978} {RNA1509_14520, RNA1509_40978, RNA815_9637.1}
22. MligTC455_12517 587 12.23 Mlig455_023517

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.412

2.599 0.790 - - 0.846 - 0.963 Mlig455_023517 {REF} {Length: 661} {RNA1509_22223} {RNA1310_60769} {RNA815_31256}
23. MligTC455_19366 2365 49.28 Mlig455_029830

Neo: -

Age: -

Region-enriched R3: 1.992/0.00057
Region-enriched R5: 1.418/0.01296

PANK3 2.582 0.789 - - 0.957 - 0.836 Mlig455_029830 {REF} {Length: 1495} {Pfam: Fumble [PF03630.16, score=108.9]} {Human: ENSG00000120137, PANK3, pantothenate kinase 3, [Score=57.0, Expect=2e-08]; ENSG00000152782, PANK1, pantothenate kinase 1, [Score=56.6, Expect=3e-08]; ENSG00000125779, PANK2, pantothenate kinase 2, [Score=55.1, Expect=5e-08]} {Mouse: ENSMUSG00000018846, Pank3, pantothenate kinase 3, [Score=56.6, Expect=2e-08]; ENSMUSG00000033610, Pank1, pantothenate kinase 1, [Score=56.2, Expect=2e-08]; ENSMUSG00000037514, Pank2, pantothenate kinase 2, [Score=55.8, Expect=4e-08]} {Dmel: FBgn0011205, fbl, fumble, [Score=55.1, Expect=5e-08]} {Smed: dd_Smed_v6_994_0_1, dd_Smed_v6_994_0_1, [RH, Score=227, Expect=2e-71]} {RNA1509_1801} {RNA1310_24657, RNA1509_1801} {RNA1509_1801, RNA815_10326}
24. MligTC455_46261 1407 29.32 Mlig455_058680

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.486

SLC26A4 2.573 - - 0.731 0.855 - 0.987 Mlig455_058680 {REF} {Length: 5357} {Pfam: Sulfate permease family [PF00916.22, score=130.2]; STAS domain [PF01740.23, score=75.4]; STAS domain [PF13466.8, score=22.3]} {Human: ENSG00000091137, SLC26A4, solute carrier family 26 member 4, [Score=134, Expect=2e-32]} {Mouse: ENSMUSG00000020651, Slc26a4, solute carrier family 26, member 4, [Score=138, Expect=4e-34]} {Dmel: FBgn0036770, Prestin, [Score=90.1, Expect=1e-18]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=131, Expect=3e-32]} {Smed: dd_Smed_v6_4250_0_2, dd_Smed_v6_4250_0_2, [Score=147, Expect=1e-37]} {RNA1509_45237} {RNA1310_6908.1} {RNA815_3307}
25. MligTC455_39351 815 16.99 Mlig455_068114

Neo: -

Age: -

RAB8B 2.541 0.738 - - 0.850 - 0.953 Mlig455_068114 {REF} {Length: 1704} {Pfam: Ras family [PF00071.24, score=174.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.7]; ADP-ribosylation factor family [PF00025.23, score=55.4]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=151, Expect=2e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [Score=145, Expect=6e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=3e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=3e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=151, Expect=1e-45]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=148, Expect=2e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=144, Expect=2e-42]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [Score=144, Expect=3e-42]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=6e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=6e-52]} {RNA1509_18167, RNA1509_19859} {RNA1310_37116, RNA1509_18167, RNA1509_19859} {RNA1509_18167, RNA1509_19859, RNA815_17007}
26. MligTC455_43923 1485 30.93 Mlig455_051179

Neo: -

Age: -

Region-enriched R3: 2.085/0.00351

SLC5A9 2.528 - - - 0.866 0.706 0.956 Mlig455_051179 {REF} {Length: 3805} {Pfam: Sodium:solute symporter family [PF00474.19, score=204.7]} {Human: ENSG00000117834, SLC5A9, solute carrier family 5 member 9, [Score=384, Expect=2e-126]; ENSG00000100170, SLC5A1, solute carrier family 5 member 1, [Score=370, Expect=4e-123]} {Mouse: ENSMUSG00000028544, Slc5a9, solute carrier family 5 (sodium/glucose cotransporter), member 9, [Score=392, Expect=1e-129]; ENSMUSG00000011034, Slc5a1, solute carrier family 5 (sodium/glucose cotransporter), member 1, [Score=384, Expect=5e-127]} {Smed: dd_Smed_v6_6663_0_1, dd_Smed_v6_6663_0_1, [Score=478, Expect=1e-163]} {RNA1509_1500, RNA1509_19405} {RNA1310_2456.1, RNA1509_1500, RNA1509_19405} {RNA1509_1500, RNA1509_19405, RNA815_1533}
27. MligTC455_46736 403 8.4 Mlig455_064968, Mlig455_066818

Neo: -

Age: -

Region-enriched R4: 2.255/0.01408

MAOA 2.528 0.747 - - 0.966 0.815 -

Mlig455_064968 {REF} {Length: 2244} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=191.6]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=43.1]; FAD dependent oxidoreductase [PF01266.26, score=30.3]; Thi4 family [PF01946.19, score=25.3]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=24.5]; HI0933-like protein [PF03486.16, score=22.6]; FAD binding domain [PF00890.26, score=21.7]; FAD dependent oxidoreductase [PF12831.9, score=20.4]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.9]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [RH, Score=229, Expect=4e-68]} {Mouse: ENSMUSG00000025037, Maoa, monoamine oxidase A, [RH, Score=236, Expect=3e-71]} {Dmel: FBgn0039177, CG13611, [RH, Score=51.2, Expect=1e-06]} {Celegans: WBGene00000138, amx-2, AMine oXidase family, [Score=78.2, Expect=5e-15]} {Smed: dd_Smed_v6_7098_0_2, dd_Smed_v6_7098_0_2, [RH, Score=325, Expect=4e-106]} {RNA1509_46542} {RNA1310_20650} {RNA815_24826}

Mlig455_066818 {REF} {Length: 1937} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=191.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=43.2]; FAD dependent oxidoreductase [PF01266.26, score=30.7]; Thi4 family [PF01946.19, score=25.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=24.4]; HI0933-like protein [PF03486.16, score=22.5]; FAD binding domain [PF00890.26, score=21.7]; FAD dependent oxidoreductase [PF12831.9, score=20.3]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.9]} {Human: ENSG00000189221, MAOA, monoamine oxidase A, [RH, Score=226, Expect=4e-67]} {Mouse: ENSMUSG00000025037, Maoa, monoamine oxidase A, [RH, Score=236, Expect=6e-71]} {Dmel: FBgn0039177, CG13611, [RH, Score=51.2, Expect=2e-06]} {Celegans: WBGene00000138, amx-2, AMine oXidase family, [Score=76.6, Expect=1e-14]} {Smed: dd_Smed_v6_6606_1_1, dd_Smed_v6_6606_1_1, [RH, Score=322, Expect=1e-104]} {RNA1509_46542, RNA1509_58749} {RNA1310_20650, RNA1509_46542, RNA1509_58749} {RNA1509_46542, RNA1509_58749, RNA815_24826}
28. MligTC455_18032 1924 40.08 Mlig455_002153, Mlig455_002252, Mlig455_002296

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.657

Region-enriched R4: 1.857/0.00029
Region-enriched R3: 1.497/0.00141

2.52 0.702 - - 0.952 - 0.866

Mlig455_002153 {REF} {Length: 4196} {Pfam: Tyrosine phosphatase family [PF13350.8, score=98.9]; Tyrosine phosphatase family [PF03162.15, score=20.4]} {Smed: dd_Smed_v6_6110_0_1, dd_Smed_v6_6110_0_1, [Score=82.4, Expect=1e-17]} {RNA1509_29961} {RNA1310_28149.1} {RNA815_13002}

Mlig455_002252 {REF} {Length: 1500} {Pfam: Tyrosine phosphatase family [PF13350.8, score=98.9]; Tyrosine phosphatase family [PF03162.15, score=21.3]} {Smed: dd_Smed_v6_6110_0_2, dd_Smed_v6_6110_0_2, [Score=80.5, Expect=2e-17]} {RNA1509_29961} {RNA1310_28149.1} {RNA815_13002}

Mlig455_002296 {REF} {Length: 1611} {Pfam: Tyrosine phosphatase family [PF13350.8, score=98.8]; Tyrosine phosphatase family [PF03162.15, score=21.3]} {Smed: dd_Smed_v6_6110_0_2, dd_Smed_v6_6110_0_2, [Score=81.3, Expect=1e-17]} {RNA1509_29961, RNA1509_38885} {RNA1310_28149.1, RNA1509_38885} {RNA1509_38885, RNA815_13002}
29. MligTC455_25421 477 9.93 Mlig455_030581

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=3.996

Region-enriched R6: 2.015/0.03172

KMO 2.484 0.771 - - 0.977 0.736 - Mlig455_030581 {REF} {Length: 1108} {Pfam: FAD binding domain [PF01494.21, score=57.0]; Squalene epoxidase [PF08491.12, score=24.6]} {Human: ENSG00000117009, KMO, kynurenine 3-monooxygenase, [Score=312, Expect=4e-103]} {Mouse: ENSMUSG00000039783, Kmo, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase), [Score=305, Expect=1e-100]} {Dmel: FBgn0000337, cn, cinnabar, [Score=234, Expect=1e-73]} {Celegans: WBGene00011089, kmo-1, Kynurenine 3-monooxygenase, [Score=300, Expect=3e-99]} {Smed: dd_Smed_v6_6831_0_1, dd_Smed_v6_6831_0_1, [Score=312, Expect=3e-104]} {RNA1509_30708, RNA1509_33201} {RNA1310_21068, RNA1509_30708} {RNA1509_30708, RNA815_8461}
30. MligTC455_33319 4306 89.7 Mlig455_027532

Neo: -

Age: logFC(26M/2M)=1.169

Region-enriched R3: 1.852/0.00003
Region-enriched R5: 1.035/0.02995

STS 2.48 0.746 - - - 0.781 0.953 Mlig455_027532 {REF} {Length: 2207} {TRANSSPLICED} {Pfam: Sulfatase [PF00884.25, score=269.3]; C-terminal region of aryl-sulfatase [PF14707.8, score=89.8]; Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=34.8]} {Human: ENSG00000101846, STS, steroid sulfatase, [RH, Score=474, Expect=2e-161]} {Mouse: ENSMUSG00000022620, Arsa, arylsulfatase A, [Score=194, Expect=7e-55]} {Dmel: FBgn0036765, CG7408, [Score=124, Expect=7e-30]} {Celegans: WBGene00006309, sul-2, SULfatase domain protein, [Score=131, Expect=6e-33]} {RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410} {RNA1310_7885.2, RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410} {RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410, RNA815_3164.1}
31. MligTC455_16062 635 13.22 Mlig455_026314

Neo: -

Age: logFC(26M/2M)=-0.923

Region-enriched R3: 2.095/0.00000
Region-enriched R4: 1.472/0.00808

SLC39A14 2.475 0.729 0.770 - 0.976 - - Mlig455_026314 {REF} {Length: 5567} {Pfam: ZIP Zinc transporter [PF02535.24, score=127.9]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=138, Expect=1e-36]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=135, Expect=5e-36]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=95.5, Expect=1e-21]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=114, Expect=8e-29]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=162, Expect=2e-46]} {RNA1509_16476} {RNA1310_12919} {RNA815_5274}
32. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 2.422 - - 0.757 0.965 0.700 -

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
33. MligTC455_25420 908 18.92 Mlig455_007536, Mlig455_024789

Neo: -

Age: -

Region-enriched R6: 1.626/0.02112

KMO 2.37 - 0.702 - 0.956 0.712 -

Mlig455_007536 {REF} {Length: 1707} {Pfam: FAD binding domain [PF01494.21, score=92.9]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=32.8]; FAD dependent oxidoreductase [PF01266.26, score=28.4]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=25.1]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=23.3]; Squalene epoxidase [PF08491.12, score=23.3]} {Human: ENSG00000117009, KMO, kynurenine 3-monooxygenase, [RH, Score=477, Expect=8e-166]} {Mouse: ENSMUSG00000039783, Kmo, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase), [RH, Score=464, Expect=5e-161]} {Dmel: FBgn0000337, cn, cinnabar, [RH, Score=341, Expect=3e-113]} {Celegans: WBGene00011089, kmo-1, Kynurenine 3-monooxygenase, [RH, Score=426, Expect=2e-146]} {Smed: dd_Smed_v6_6831_0_1, dd_Smed_v6_6831_0_1, [RH, Score=422, Expect=3e-145]} {RNA1509_33201} {RNA1310_21068, RNA1509_33201} {RNA1509_33201, RNA815_8461}

Mlig455_024789 {REF} {Length: 1709} {Pfam: FAD binding domain [PF01494.21, score=95.6]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=31.0]; FAD dependent oxidoreductase [PF01266.26, score=29.3]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=24.9]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=23.4]; Squalene epoxidase [PF08491.12, score=23.3]} {Human: ENSG00000117009, KMO, kynurenine 3-monooxygenase, [RH, Score=476, Expect=2e-165]} {Mouse: ENSMUSG00000039783, Kmo, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase), [RH, Score=460, Expect=3e-159]} {Dmel: FBgn0000337, cn, cinnabar, [RH, Score=341, Expect=2e-113]} {Celegans: WBGene00011089, kmo-1, Kynurenine 3-monooxygenase, [RH, Score=429, Expect=1e-147]} {Smed: dd_Smed_v6_6831_0_1, dd_Smed_v6_6831_0_1, [RH, Score=425, Expect=3e-146]} {RNA1509_33201} {RNA1310_21068} {RNA815_8461}
34. MligTC455_24363 1243 25.89 Mlig455_065691

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.713

MOGAT2 1.86 - - - - 0.951 0.909 Mlig455_065691 {REF} {Length: 3352} {TRANSSPLICED} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=385.5]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [RH, Score=341, Expect=3e-111]; ENSG00000124003, MOGAT1, monoacylglycerol O-acyltransferase 1, [RH, Score=341, Expect=2e-111]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [RH, Score=343, Expect=2e-112]; ENSMUSG00000012187, Mogat1, monoacylglycerol O-acyltransferase 1, [RH, Score=338, Expect=2e-110]} {Dmel: FBgn0033214, CG1941, [RH, Score=243, Expect=8e-74]} {Celegans: WBGene00019464, K07B1.4, [RH, Score=323, Expect=2e-104]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [RH, Score=395, Expect=7e-133]} {RNA1509_22728} {RNA1310_14435.2} {RNA815_3120.1}
35. MligTC455_44699 2074 43.2 Mlig455_048395

Neo: -

Age: logFC(26M/2M)=0.553

Region-enriched R3: 1.711/0.00637

SLC10A5 1.808 0.856 - - 0.952 - - Mlig455_048395 {REF} {Length: 1771} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=116.4]} {Human: ENSG00000253598, SLC10A5, solute carrier family 10 member 5, [RH, Score=130, Expect=9e-33]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=2e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=129, Expect=4e-33]; ENSMUSG00000058921, Slc10a5, solute carrier family 10 (sodium/bile acid cotransporter family), member 5, [Score=125, Expect=6e-31]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=9e-31]} {Dmel: FBgn0030756, CG9903, [Score=103, Expect=1e-23]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=206, Expect=4e-60]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [RH, Score=295, Expect=3e-95]} {RNA1509_51285} {RNA1310_359.1} {RNA815_3102}
36. MligTC455_52621 424 8.82 Mlig455_049022, Mlig455_051566

Neo: -

Age: -

1.806 - - - 0.984 0.822 -

Mlig455_049022 {REF} {Length: 6067} {RNA1509_34465} {RNA1310_12955.1} {RNA815_5479.1}

Mlig455_051566 {REF} {Length: 2215} {RNA1509_34465} {RNA1310_22031} {RNA815_5479.1}
37. MligTC455_34417 337 7.03 Mlig455_037242

Neo: -

Age: -

1.805 0.828 - - - - 0.977 Mlig455_037242 {REF} {Length: 1622} {RNA1509_21160} {RNA1310_6052} {RNA815_3316}
38. MligTC455_40876 1006 20.96 Mlig455_028183

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.153/0.01519
Region-enriched R3: 1.090/0.00901

ETHE1 1.793 0.843 - - - - 0.950 Mlig455_028183 {REF} {Length: 1716} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=323, Expect=6e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=321, Expect=4e-111]} {Dmel: FBgn0050022, CG30022, [RH, Score=292, Expect=2e-99]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=286, Expect=1e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=318, Expect=2e-110]} {RNA1509_7310} {RNA1310_16001.1} {RNA815_19195}
39. MligTC455_24849 360 7.5 Mlig455_037655, Mlig455_037662, Mlig455_037767

Neo: -

Age: -

1.79 0.820 - - 0.970 - -

Mlig455_037655 {REF} {Length: 1631} {RNA1509_10628} {RNA1310_36432.1} {RNA815_18532}

Mlig455_037662 {REF} {Length: 1036} {RNA1310_36432.1} {RNA815_18532}

Mlig455_037767 {REF} {Length: 1739} {RNA1509_10628} {RNA1310_36432.1} {RNA815_18532}
40. MligTC455_33103 818 17.04 Mlig455_049936

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.704

Region-enriched R3: 1.236/0.01404

SLC47A1 1.787 - - 0.834 0.953 - - Mlig455_049936 {REF} {Length: 2568} {Pfam: MatE [PF01554.20, score=107.5]} {Human: ENSG00000142494, SLC47A1, solute carrier family 47 member 1, [Score=187, Expect=1e-51]} {Mouse: ENSMUSG00000069855, Slc47a2, solute carrier family 47, member 2, [Score=199, Expect=2e-56]; ENSMUSG00000010122, Slc47a1, solute carrier family 47, member 1, [Score=196, Expect=2e-55]} {Smed: dd_Smed_v6_8335_0_4, dd_Smed_v6_8335_0_4, [Score=212, Expect=3e-61]} {RNA1509_22002, RNA1509_22354, RNA1509_36610, RNA1509_39570} {RNA1310_12106.1, RNA1509_22002, RNA1509_22354, RNA1509_36610, RNA1509_39570} {RNA1509_22002, RNA1509_22354, RNA1509_36610, RNA1509_39570, RNA815_4765}
41. MligTC455_41168 783 16.32 Mlig455_040980

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=3.358

Region-enriched R3: 2.227/0.04212

NCAN 1.78 0.826 - - - 0.954 - Mlig455_040980 {REF} {Length: 1564} {Pfam: Lectin C-type domain [PF00059.23, score=61.9]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=20.4]} {Human: ENSG00000130287, NCAN, neurocan, [Score=67.0, Expect=1e-11]} {Mouse: ENSMUSG00000002341, Ncan, neurocan, [Score=65.9, Expect=2e-11]} {Celegans: WBGene00020585, clec-178, C-type LECtin, [Score=63.2, Expect=7e-12]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=55.5, Expect=1e-08]} {RNA1509_14206, RNA1509_23243, RNA1509_23770, RNA1509_35580, RNA1509_4111, RNA1509_49810} {RNA1310_16505.2, RNA1509_14206, RNA1509_23243, RNA1509_23770, RNA1509_35580, RNA1509_4111, RNA1509_49810} {RNA1509_14206, RNA1509_23243, RNA1509_23770, RNA1509_35580, RNA1509_4111, RNA1509_49810, RNA815_8835}
42. MligTC455_44400 1523 31.72 Mlig455_021226, Mlig455_021227

Neo: -

Age: Up-Down-Down

Region-enriched R3: 3.894/0.00002
Region-enriched R4: 2.980/0.01366

1.768 - - - 0.814 - 0.954

Mlig455_021226 {REF} {Length: 1606} {RNA1509_6315} {RNA1310_29655} {RNA815_4464.1}

Mlig455_021227 {REF} {Length: 1529} {RNA1509_6315} {RNA1310_29655} {RNA815_4464.1}
43. MligTC455_12954 637 13.27 Mlig455_008009

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.547

Region-enriched R3: 1.755/0.00048

ENPP1 1.763 - - - 0.951 0.812 - Mlig455_008009 {REF} {Length: 1580} {Pfam: Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=280.2]; Sulfatase [PF00884.25, score=23.7]} {Human: ENSG00000197594, ENPP1, ectonucleotide pyrophosphatase/phosphodiesterase 1, [RH, Score=284, Expect=2e-86]; ENSG00000001561, ENPP4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [RH, Score=282, Expect=3e-90]} {Mouse: ENSMUSG00000023961, Enpp4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [RH, Score=282, Expect=2e-90]; ENSMUSG00000023960, Enpp5, ectonucleotide pyrophosphatase/phosphodiesterase 5, [RH, Score=276, Expect=6e-88]; ENSMUSG00000037370, Enpp1, ectonucleotide pyrophosphatase/phosphodiesterase 1, [RH, Score=270, Expect=1e-81]} {Celegans: WBGene00007755, C27A7.3, Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.3, [RH, Score=166, Expect=9e-45]} {Smed: dd_Smed_v6_9016_0_1, dd_Smed_v6_9016_0_1, [RH, Score=223, Expect=2e-67]} {RNA1509_40246, RNA1509_40829, RNA1509_4220, RNA1509_47985} {RNA1310_25457, RNA1509_40246, RNA1509_40829, RNA1509_47985} {RNA1509_40246, RNA1509_40829, RNA1509_47985, RNA815_4584.2}
44. MligTC455_35661 2224 46.33 Mlig455_000469

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.429/0.00194

AC099489.1 1.757 - 0.801 - 0.956 - - Mlig455_000469 {REF} {Length: 15150} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=91.3]; Domain of unknown function (DUF1943) [PF09172.13, score=65.8]; von Willebrand factor type D domain [PF00094.27, score=29.6]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=128, Expect=3e-28]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=72.0, Expect=2e-11]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=97.1, Expect=2e-19]} {RNA1509_18517, RNA1509_862} {RNA1310_65.1, RNA1509_18517} {RNA1509_18517, RNA815_55}
45. MligTC455_47849 29 0.61 Mlig455_011075

Neo: -

Age: logFC(26M/2M)=0.550

1.755 - - - 0.952 0.803 - Mlig455_011075 {REF} {Length: 1303} {TRANSSPLICED} {RNA1509_33971, RNA1509_45945} {RNA1310_23556, RNA1509_33971, RNA1509_45945} {RNA1509_33971, RNA1509_45945, RNA815_23556}
46. MligTC455_16462 248 5.17 Mlig455_058597

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.200/0.02502
Region-enriched R3: 2.087/0.02407
Region-enriched R5: 1.741/0.03183

1.752 0.790 - - 0.962 - - Mlig455_058597 {REF} {Length: 2499} {RNA1509_26769, RNA1509_36389, RNA1509_43355} {RNA1310_44087, RNA1509_26769, RNA1509_36389, RNA1509_43355} {RNA1509_26769, RNA1509_36389, RNA1509_43355, RNA815_22536}
47. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 1.737 0.781 - - 0.956 - -

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
48. MligTC455_31952 223 4.64 Mlig455_023381

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.827

Region-enriched R3: 3.025/0.02384

1.704 - - - 0.951 0.753 - Mlig455_023381 {REF} {Length: 3446} {Pfam: Protein of unknown function (DUF229) [PF02995.19, score=268.1]; Sulfatase [PF00884.25, score=18.1]} {Dmel: FBgn0038318, CG6236, [Score=280, Expect=2e-84]} {Celegans: WBGene00012762, Y41E3.1, [Score=270, Expect=9e-81]} {Smed: dd_Smed_v6_4842_0_1, dd_Smed_v6_4842_0_1, [Score=206, Expect=4e-58]} {RNA1509_31552} {RNA1310_4186} {RNA815_5600}
49. MligTC455_52104 259 5.39 Mlig455_054545

Neo: -

Age: -

CCNT1 0.991 - - - 0.991 - - Mlig455_054545 {REF} {Length: 4031} {Pfam: Cyclin, N-terminal domain [PF00134.25, score=42.3]; Transcription factor TFIIB repeat [PF00382.21, score=23.7]} {Human: ENSG00000129315, CCNT1, cyclin T1, [RH, Score=151, Expect=8e-38]; ENSG00000082258, CCNT2, cyclin T2, [RH, Score=149, Expect=2e-37]} {Mouse: ENSMUSG00000026349, Ccnt2, cyclin T2, [RH, Score=148, Expect=6e-37]; ENSMUSG00000011960, Ccnt1, cyclin T1, [RH, Score=145, Expect=3e-36]} {Dmel: FBgn0025455, CycT, Cyclin T, [RH, Score=145, Expect=5e-36]} {Celegans: WBGene00000507, cit-1.1, Cyclin-T1.1, [RH, Score=95.1, Expect=2e-20]} {Smed: dd_Smed_v6_1288_0_1, dd_Smed_v6_1288_0_1, [RH, Score=107, Expect=6e-25]} {RNA1509_14385, RNA1509_35510} {RNA1310_14446, RNA1509_35510} {RNA1509_35510, RNA815_13055}
50. MligTC455_52622 207 4.31 Mlig455_062511, Mlig455_067746

Neo: -

Age: Up-Down-Up

Region-enriched R4: 5.081/0.00002

0.977 - - - 0.977 - -

Mlig455_062511 {REF} {Length: 1645} {RNA1509_34465} {RNA1310_45633} {RNA815_5479.1}

Mlig455_067746 {REF} {Length: 2852} {RNA1509_34465} {RNA1310_12955.1} {RNA815_5479.1}
51. MligTC455_10784 1017 21.18 Mlig455_060178, Mlig455_067094

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.724/0.00469
Region-enriched R3: 1.524/0.00347

0.971 - - - 0.971 - -

Mlig455_060178 {REF} {Length: 6205} {Pfam: Laminin G domain [PF02210.26, score=29.6]; Laminin G domain [PF00054.25, score=25.5]} {RNA1509_3538} {RNA1310_3085.1, RNA1509_3538} {RNA1509_3538, RNA815_1617}

Mlig455_067094 {REF} {Length: 4035} {Pfam: Laminin G domain [PF02210.26, score=29.6]; Laminin G domain [PF00054.25, score=25.5]} {RNA1509_3538, RNA1509_57795} {RNA1310_3085.1, RNA1509_57795} {RNA1509_57795, RNA815_1617}
52. MligTC455_28551 277 5.76 Mlig455_069748

Neo: -

Age: -

NDRG1 0.969 - - - 0.969 - - Mlig455_069748 {REF} {Length: 2579} {TRANSSPLICED} {Pfam: Ndr family [PF03096.16, score=186.2]} {Human: ENSG00000104419, NDRG1, N-myc downstream regulated 1, [Score=125, Expect=9e-32]; ENSG00000101079, NDRG3, NDRG family member 3, [Score=122, Expect=1e-30]} {Mouse: ENSMUSG00000027634, Ndrg3, N-myc downstream regulated gene 3, [Score=119, Expect=1e-29]; ENSMUSG00000005125, Ndrg1, N-myc downstream regulated gene 1, [Score=118, Expect=3e-29]} {Dmel: FBgn0043070, MESK2, Misexpression suppressor of KSR 2, [Score=127, Expect=2e-32]} {Celegans: WBGene00013020, Y48G10A.3, [RH, Score=117, Expect=1e-29]} {Smed: dd_Smed_v6_1911_0_1, dd_Smed_v6_1911_0_1, [Score=226, Expect=2e-70]} {RNA1509_13688} {RNA1310_24392} {RNA815_9919}
53. MligTC455_43485 1018 21.21 Mlig455_010044

Neo: -

Age: logFC(26M/2M)=1.232

Region-enriched R3: 2.130/0.00002

0.965 - - - - - 0.965 Mlig455_010044 {REF} {Length: 1690} {TRANSSPLICED} {Dmel: FBgn0040342, CG3706, [Score=130, Expect=3e-33]} {Celegans: WBGene00015469, C05D2.8, [Score=168, Expect=1e-47]} {Smed: dd_Smed_v6_8821_0_1, dd_Smed_v6_8821_0_1, [RH, Score=229, Expect=1e-71]} {RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1310_12594.1, RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1509_13716, RNA1509_54778, RNA1509_9788, RNA815_5664}
54. MligTC455_12009 131 2.73 Mlig455_050443

Neo: -

Age: -

SLC5A3 0.958 - - - 0.958 - - Mlig455_050443 {REF} {Length: 2819} {tRNA: Val(CAC),pseudo, score=28.9} {Pfam: Sodium:solute symporter family [PF00474.19, score=325.5]} {Human: ENSG00000198743, SLC5A3, solute carrier family 5 member 3, [Score=428, Expect=1e-140]; ENSG00000158865, SLC5A11, solute carrier family 5 member 11, [Score=416, Expect=1e-136]; ENSG00000117834, SLC5A9, solute carrier family 5 member 9, [Score=416, Expect=1e-136]; ENSG00000100170, SLC5A1, solute carrier family 5 member 1, [Score=410, Expect=2e-134]; ENSG00000154025, SLC5A10, solute carrier family 5 member 10, [Score=407, Expect=5e-134]} {Mouse: ENSMUSG00000089774, Slc5a3, solute carrier family 5 (inositol transporters), member 3, [Score=427, Expect=3e-140]; ENSMUSG00000028544, Slc5a9, solute carrier family 5 (sodium/glucose cotransporter), member 9, [Score=426, Expect=1e-140]; ENSMUSG00000042371, Slc5a10, solute carrier family 5 (sodium/glucose cotransporter), member 10, [Score=424, Expect=6e-141]; ENSMUSG00000030769, Slc5a11, solute carrier family 5 (sodium/glucose cotransporter), member 11, [Score=423, Expect=2e-139]; ENSMUSG00000020229, Slc5a4a, solute carrier family 5, member 4a, [Score=411, Expect=3e-135]; ENSMUSG00000020226, Slc5a4b, solute carrier family 5 (neutral amino acid transporters, system A), member 4b, [Score=407, Expect=3e-133]} {Dmel: FBgn0034494, CG10444, [Score=89.7, Expect=2e-18]} {Smed: dd_Smed_v6_6663_0_1, dd_Smed_v6_6663_0_1, [Score=396, Expect=1e-129]} {RNA1509_24057} {RNA1310_13263, RNA1509_24057} {RNA1509_24057, RNA815_25000}
55. MligTC455_16063 772 16.08 Mlig455_026358, Mlig455_052707

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.372

Region-enriched R3: 2.027/0.00000
Region-enriched R4: 1.354/0.01177

SLC39A14 0.956 - - - 0.956 - -

Mlig455_026358 {REF} {Length: 2562} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.7]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=4e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=3e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=185, Expect=3e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=5e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=161, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_35963, RNA1509_39667} {RNA1310_11294, RNA1509_39667} {RNA1509_39667, RNA815_5274}

Mlig455_052707 {REF} {Length: 2641} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.7]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=4e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=3e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=185, Expect=3e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=5e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=161, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_35963, RNA1509_50293} {RNA1310_11294, RNA1509_35963, RNA1509_50293} {RNA1509_35963, RNA1509_50293, RNA815_5274}
56. MligTC455_22145 125 2.6 Mlig455_016022

Neo: -

Age: Down-Up-Down

XDH 0.952 - - - 0.952 - - Mlig455_016022 {REF} {Length: 5213} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=235.6]; [2Fe-2S] binding domain [PF01799.22, score=95.9]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=92.7]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=77.2]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=69.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=25.1]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=347, Expect=2e-100]; ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=346, Expect=3e-100]} {Mouse: ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=363, Expect=1e-106]; ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=357, Expect=3e-104]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=532, Expect=3e-169]} {Celegans: WBGene00010083, xhd-1, [Score=357, Expect=2e-104]} {RNA1509_325} {RNA1310_1603.1} {RNA815_224.1}
57. MligTC455_43368 6858 142.86 Mlig455_048986, Mlig455_049002

Neo: -

Age: Up-Down-Down

ACHE 0.95 - - - - - 0.950

Mlig455_048986 {REF} {Length: 14781} {Pfam: Carboxylesterase family [PF00135.30, score=2484.2]; alpha/beta hydrolase fold [PF07859.15, score=129.3]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=8e-66]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=209, Expect=1e-56]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=189, Expect=3e-49]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=213, Expect=1e-57]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=202, Expect=8e-54]} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_82, RNA1509_8879} {RNA1310_83.1, RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879, RNA815_40.1}

Mlig455_049002 {REF} {Length: 15214} {Pfam: Carboxylesterase family [PF00135.30, score=2695.8]; alpha/beta hydrolase fold [PF07859.15, score=131.9]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=1e-65]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=211, Expect=7e-57]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=5e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=207, Expect=1e-55]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=199, Expect=5e-53]} {RNA1509_82, RNA1509_8738} {RNA1310_83.1, RNA1509_8738} {RNA1509_8738, RNA815_40.1}
58. MligTC455_52105 520 10.82 Mlig455_036272, Mlig455_055399

Neo: -

Age: -

0.95 - - - 0.950 - -

Mlig455_036272 {REF} {Length: 1988} {TRANSSPLICED} {RNA1509_30629} {RNA1310_57866, RNA1509_30629} {RNA1509_30629, RNA815_32309}

Mlig455_055399 {REF} {Length: 1930} {TRANSSPLICED} {RNA1509_30629} {RNA1310_57866} {RNA815_32309}

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