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Results for MligTC455_40876

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_40876 1006 20.96 Mlig455_028183

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.153/0.01519
Region-enriched R3: 1.090/0.00901

 ETHE1 Mlig455_028183 {REF} {Length: 1716} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=323, Expect=6e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=321, Expect=4e-111]} {Dmel: FBgn0050022, CG30022, [RH, Score=292, Expect=2e-99]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=286, Expect=1e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=318, Expect=2e-110]} {RNA1509_7310} {RNA1310_16001.1} {RNA815_19195}

Cumulative graph for MligTC455_40876

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.414 4.573 0.59871 1.00000
RegionR2 -0.952 4.573 0.02357 0.17057
RegionR3 1.09 4.573 0.00023 0.00901
RegionR4 1.153 4.573 0.00162 0.01519
RegionR5 0.876 4.573 0.00157 0.01448
RegionR6 0.228 4.573 0.48173 1.00000
RegionR7 -1.04 4.573 0.02207 0.27606
RegionR8 -1.769 4.573 0.00282 0.09152

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.082 4.573 0.93455 1.00000
RegenerationR2 -0.893 4.573 0.02896 0.28052
RegenerationR3 -1.215 4.573 0.00082 0.04430
RegenerationR4 -0.98 4.573 0.00859 0.13837
RegenerationR5 -0.528 4.573 0.12245 0.52344
RegenerationR6 -0.745 4.573 0.06069 0.30974
RegenerationBL -0.239 4.573 0.67178 1.00000
RegenerationTP -0.659 4.573 0.32294 0.76717


Genes with expression patterns similar to MligTC455_40876

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_40876 1006 20.96 Mlig455_028183

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.153/0.01519
Region-enriched R3: 1.090/0.00901

 ETHE1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_028183 {REF} {Length: 1716} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=323, Expect=6e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=321, Expect=4e-111]} {Dmel: FBgn0050022, CG30022, [RH, Score=292, Expect=2e-99]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=286, Expect=1e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=318, Expect=2e-110]} {RNA1509_7310} {RNA1310_16001.1} {RNA815_19195}
2. MligTC455_40877 940 19.59 Mlig455_028254

Neo: -

Age: -

Region-enriched R4: 1.189/0.01108
Region-enriched R3: 1.015/0.01751

 ETHE1 4.962 0.995 0.994 0.993 0.997 0.983 - Mlig455_028254 {REF} {Length: 1819} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=325, Expect=1e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=322, Expect=1e-111]} {Dmel: FBgn0050022, CG30022, [Score=290, Expect=1e-98]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=285, Expect=3e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=317, Expect=9e-110]} {RNA1509_7310} {RNA1310_16001.1, RNA1509_7310} {RNA1509_7310, RNA815_19195}
3. MligTC455_26168 821 17.11 Mlig455_019363

Neo: -

Age: logFC(26M/2M)=0.387

Region-enriched R5: 1.107/0.01127

 2.697 0.854 - - 0.879 - 0.964 Mlig455_019363 {REF} {Length: 4266} {TRANSSPLICED} {Pfam: Prokaryotic RING finger family 4 [PF14447.8, score=20.2]} {RNA1509_42908, RNA1509_8681} {RNA1310_8559, RNA1509_42908, RNA1509_8681} {RNA1509_42908, RNA1509_8681, RNA815_6586}
4. MligTC455_31182 1394 29.04 Mlig455_053151

Neo: -

Age: -

Region-enriched R6: 3.486/0.00001
Region-enriched R5: 3.334/0.00000
Region-enriched R4: 3.071/0.00047
Region-enriched R3: 2.674/0.00253

 ANPEP 2.649 0.782 - - 0.965 - 0.902 Mlig455_053151 {REF} {Length: 4509} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=262.3]; Peptidase family M1 domain [PF01433.22, score=247.1]; Peptidase M1 N-terminal domain [PF17900.3, score=145.8]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [RH, Score=581, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=574, Expect=0.0]} {Dmel: FBgn0039640, CG14516, [RH, Score=538, Expect=9e-176]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [RH, Score=436, Expect=8e-137]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [RH, Score=639, Expect=0.0]} {RNA1509_13872, RNA1509_1573, RNA1509_32492} {RNA1310_1662.1, RNA1509_13872, RNA1509_32492} {RNA1509_13872, RNA1509_32492, RNA815_486.1}
5. MligTC455_24869 3528 73.49 Mlig455_039885, Mlig455_039903, Mlig455_039939

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.614/0.00079

 MRC1 2.593 0.801 - - 0.973 0.819 -

Mlig455_039885 {REF} {Length: 6516} {Pfam: Lectin C-type domain [PF00059.23, score=685.5]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=75.5]; Extracellular link domain [PF00193.19, score=22.7]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=492, Expect=6e-146]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=494, Expect=1e-146]} {Dmel: FBgn0040102, lectin-24Db, [RH, Score=72.0, Expect=1e-12]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [RH, Score=95.1, Expect=1e-20]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [RH, Score=228, Expect=4e-60]} {RNA1509_240} {RNA1310_205.1} {RNA815_95}

Mlig455_039903 {REF} {Length: 6532} {Pfam: Lectin C-type domain [PF00059.23, score=559.4]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=65.7]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=365, Expect=9e-104]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=348, Expect=5e-98]} {Dmel: FBgn0040102, lectin-24Db, [RH, Score=71.6, Expect=1e-12]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [RH, Score=94.0, Expect=2e-20]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=202, Expect=2e-52]} {RNA1509_23542, RNA1509_240, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472} {RNA1310_205.1, RNA1509_23542, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472} {RNA1509_23542, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472, RNA815_95}

Mlig455_039939 {REF} {Length: 6496} {Pfam: Lectin C-type domain [PF00059.23, score=267.5]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=42.5]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=180, Expect=2e-46]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=172, Expect=6e-44]} {Dmel: FBgn0035199, tfc, triforce, [Score=60.8, Expect=2e-10]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [Score=89.0, Expect=4e-19]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=99.0, Expect=4e-21]} {RNA1509_240} {RNA1310_205.1} {RNA815_95}
6. MligTC455_34829 1291 26.9 Mlig455_060253

Neo: Neoblast

Age: -

 DDX3X 2.48 0.711 - - 0.956 0.813 - Mlig455_060253 {REF} {Length: 3237} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=134.3]; Helicase conserved C-terminal domain [PF00271.33, score=101.1]} {Human: ENSG00000215301, DDX3X, DEAD-box helicase 3 X-linked, [Score=278, Expect=4e-85]; ENSG00000067048, DDX3Y, DEAD-box helicase 3 Y-linked, [Score=276, Expect=7e-84]} {Mouse: ENSMUSG00000039224, D1Pas1, DNA segment, Chr 1, Pasteur Institute 1, [Score=279, Expect=4e-85]; ENSMUSG00000000787, Ddx3x, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked, [Score=277, Expect=1e-84]; ENSMUSG00000069045, Ddx3y, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked, [Score=275, Expect=1e-83]} {Dmel: FBgn0263231, bel, belle, [Score=266, Expect=2e-79]} {Celegans: WBGene00006888, vbh-1, Vasa-and Belle-like Helicase, [Score=274, Expect=7e-84]} {Smed: dd_Smed_v6_799_0_1, dd_Smed_v6_799_0_1, [RH, Score=282, Expect=1e-87]} {RNA1509_12917, RNA1509_14198, RNA1509_19222, RNA1509_32018, RNA1509_56153} {RNA1310_15697, RNA1509_12917, RNA1509_14198, RNA1509_19222, RNA1509_32018, RNA1509_56153} {RNA1509_12917, RNA1509_14198, RNA1509_19222, RNA1509_32018, RNA1509_56153, RNA815_8275}
7. MligTC455_16407 3778 78.72 Mlig455_037803

Neo: Int S/G2/M

Age: -

 DAP 2.448 - 0.703 - 0.963 - 0.782 Mlig455_037803 {REF} {Length: 1161} {TRANSSPLICED} {Pfam: Death-associated protein [PF15228.8, score=59.8]} {Human: ENSG00000112977, DAP, death associated protein, [RH, Score=48.1, Expect=5e-08]} {Mouse: ENSMUSG00000039168, Dap, death-associated protein, [RH, Score=48.5, Expect=1e-08]} {Smed: dd_Smed_v6_955_0_1, dd_Smed_v6_955_0_1, [Score=64.7, Expect=4e-15]} {RNA1509_11324, RNA1509_1481, RNA1509_18730, RNA1509_2237, RNA1509_3397, RNA1509_45499, RNA1509_5781, RNA1509_6608, RNA1509_7085, RNA1509_8875} {RNA1310_1871, RNA1509_11324, RNA1509_1481, RNA1509_18730, RNA1509_2237, RNA1509_3397, RNA1509_45499, RNA1509_5781, RNA1509_6608, RNA1509_7085, RNA1509_8875} {RNA1509_11324, RNA1509_1481, RNA1509_18730, RNA1509_2237, RNA1509_3397, RNA1509_45499, RNA1509_5781, RNA1509_6608, RNA1509_7085, RNA1509_8875, RNA815_11385}
8. MligTC455_34207 12055 251.14 Mlig455_035831

Neo: -

Age: logFC(26M/2M)=0.753

Region-enriched R3: 1.887/0.00004

Regeneration-upregulated TP: 2.075

Regeneration-enriched TP: 2.075

 AC099489.1 2.389 0.732 - - 0.953 - 0.704 Mlig455_035831 {REF} {Length: 10908} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=126.2]; Domain of unknown function (DUF1943) [PF09172.13, score=95.1]; von Willebrand factor type D domain [PF00094.27, score=31.2]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=65.5, Expect=2e-09]} {Mouse: ENSMUSG00000020609, Apob, apolipoprotein B, [Score=57.8, Expect=3e-07]} {Dmel: FBgn0087002, apolpp, apolipophorin, [Score=77.0, Expect=4e-13]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=145, Expect=4e-34]} {RNA1509_19, RNA1509_35407} {RNA1310_78, RNA1509_35407} {RNA1509_35407, RNA815_36.1}
9. MligTC455_22727 5187 108.07 Mlig455_010977

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.553

Region-enriched R3: 1.735/0.00293

 AC099489.1 1.829 - - - 0.877 - 0.952 Mlig455_010977 {REF} {Length: 21890} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=254.0]; Domain of unknown function (DUF1943) [PF09172.13, score=215.5]; von Willebrand factor type D domain [PF00094.27, score=65.0]; Domain of Unknown Function (DUF1081) [PF06448.13, score=32.0]; C8 domain [PF08742.13, score=24.1]; HEAT repeats [PF13646.8, score=20.4]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [RH, Score=374, Expect=2e-102]} {Mouse: ENSMUSG00000020609, Apob, apolipoprotein B, [RH, Score=177, Expect=8e-43]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [RH, Score=304, Expect=2e-81]} {Smed: dd_Smed_v6_194_0_1, dd_Smed_v6_194_0_1, [RH, Score=538, Expect=2e-152]} {RNA1509_23, RNA1509_42468, RNA1509_9014, RNA1509_935} {RNA1310_8.1, RNA1509_42468, RNA1509_9014, RNA1509_935} {RNA1509_42468, RNA1509_9014, RNA1509_935, RNA815_6.1}
10. MligTC455_27982 2224 46.32 Mlig455_014695, Mlig455_014738

Neo: -

Age: -

Region-enriched R3: 1.878/0.03979

 SLC9A3R2 1.802 0.831 - - 0.971 - -

Mlig455_014695 {REF} {Length: 1932} {Pfam: PDZ domain [PF00595.26, score=39.6]; PDZ domain [PF17820.3, score=26.5]; PDZ domain [PF13180.8, score=25.5]} {Human: ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=94.7, Expect=8e-22]} {Mouse: ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=96.7, Expect=2e-22]; ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=93.6, Expect=1e-21]} {Dmel: FBgn0010620, CG10939, [Score=87.0, Expect=1e-19]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=89.7, Expect=5e-20]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=107, Expect=2e-28]} {RNA1509_5277, RNA1509_8845} {RNA1310_17362, RNA1509_5277, RNA1509_8845} {RNA1509_5277, RNA1509_8845, RNA815_22754.1}

Mlig455_014738 {REF} {Length: 1929} {Pfam: PDZ domain [PF00595.26, score=41.4]; PDZ domain [PF17820.3, score=26.4]; PDZ domain [PF13180.8, score=23.8]} {Human: ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=97.4, Expect=7e-23]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=96.7, Expect=1e-22]; ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=95.9, Expect=3e-22]} {Dmel: FBgn0010620, CG10939, [Score=89.7, Expect=2e-20]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=92.4, Expect=5e-21]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=110, Expect=3e-29]} {RNA1509_39084} {RNA1310_17362, RNA1509_39084} {RNA1509_39084, RNA815_22754.1}
11. MligTC455_36058 498 10.38 Mlig455_056788

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.316

 SACS 1.8 - - - 0.967 0.833 - Mlig455_056788 {REF} {Length: 11328} {Pfam: HEPN domain [PF05168.16, score=25.7]; Protein of unknown function (DUF3684) [PF12449.10, score=21.5]} {Human: ENSG00000151835, SACS, sacsin molecular chaperone, [RH, Score=694, Expect=0.0]} {Mouse: ENSMUSG00000048279, Sacs, sacsin, [Score=674, Expect=0.0]} {RNA1509_9376} {RNA1310_179.1} {RNA815_106.1}
12. MligTC455_36059 491 10.22 Mlig455_056789

Neo: -

Age: Up-Down-Down

 SACS 1.796 - - - 0.969 0.827 - Mlig455_056789 {REF} {Length: 11102} {Human: ENSG00000151835, SACS, sacsin molecular chaperone, [RH, Score=662, Expect=0.0]} {Mouse: ENSMUSG00000048279, Sacs, sacsin, [RH, Score=642, Expect=0.0]} {RNA1509_9376} {RNA1310_179.1} {RNA815_106.1}
13. MligTC455_19022 687 14.31 Mlig455_037405

Neo: -

Age: -

Region-enriched R3: 1.615/0.00300
Region-enriched R5: 1.137/0.02464

 GRINA 1.793 0.843 - - - - 0.950 Mlig455_037405 {REF} {Length: 2190} {Pfam: Inhibitor of apoptosis-promoting Bax1 [PF01027.22, score=72.3]} {Human: ENSG00000178719, GRINA, glutamate ionotropic receptor NMDA type subunit associated protein 1, [Score=163, Expect=3e-47]} {Mouse: ENSMUSG00000022564, Grina, glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding), [Score=145, Expect=4e-41]; ENSMUSG00000023011, Faim2, Fas apoptotic inhibitory molecule 2, [Score=144, Expect=8e-41]} {Dmel: FBgn0013305, Nmda1, N-methyl-D-aspartate receptor-associated protein, [Score=155, Expect=6e-45]} {Celegans: WBGene00006470, tag-120, [Score=111, Expect=4e-29]} {Smed: dd_Smed_v6_1586_0_1, dd_Smed_v6_1586_0_1, [Score=171, Expect=9e-52]} {RNA1509_32288} {RNA1310_27497.1, RNA1509_32288} {RNA1509_32288, RNA815_12093}
14. MligTC455_43485 1018 21.21 Mlig455_010044

Neo: -

Age: logFC(26M/2M)=1.232

Region-enriched R3: 2.130/0.00002

 1.769 - - - 0.818 - 0.951 Mlig455_010044 {REF} {Length: 1690} {TRANSSPLICED} {Dmel: FBgn0040342, CG3706, [Score=130, Expect=3e-33]} {Celegans: WBGene00015469, C05D2.8, [Score=168, Expect=1e-47]} {Smed: dd_Smed_v6_8821_0_1, dd_Smed_v6_8821_0_1, [RH, Score=229, Expect=1e-71]} {RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1310_12594.1, RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1509_13716, RNA1509_54778, RNA1509_9788, RNA815_5664}
15. MligTC455_35906 4161 86.69 Mlig455_035377

Neo: -

Age: -

 ATP6V1A 1.764 - 0.807 - 0.957 - - Mlig455_035377 {REF} {Length: 3663} {TRANSSPLICED} {Pfam: ATP synthase alpha/beta family, nucleotide-binding domain [PF00006.27, score=353.9]; ATPsynthase alpha/beta subunit N-term extension [PF16886.7, score=141.5]; ATP synthase alpha/beta family, beta-barrel domain [PF02874.25, score=47.5]} {Human: ENSG00000114573, ATP6V1A, ATPase H+ transporting V1 subunit A, [RH, Score=999, Expect=0.0]} {Mouse: ENSMUSG00000052459, Atp6v1a, ATPase, H+ transporting, lysosomal V1 subunit A, [RH, Score=997, Expect=0.0]} {Dmel: FBgn0263598, Vha68-2, Vacuolar H[+] ATPase 68 kDa subunit 2, [RH, Score=1001, Expect=0.0]} {Celegans: WBGene00013025, vha-13, V-type proton ATPase catalytic subunit A, [RH, Score=963, Expect=0.0]} {Smed: dd_Smed_v6_959_0_1, dd_Smed_v6_959_0_1, [RH, Score=985, Expect=0.0]} {RNA1509_12772, RNA1509_1406, RNA1509_15139, RNA1509_30164, RNA1509_34338, RNA1509_38982, RNA1509_39853, RNA1509_42482} {RNA1310_8083.1, RNA1509_12772, RNA1509_1406, RNA1509_15139, RNA1509_30164, RNA1509_34338, RNA1509_38982, RNA1509_39853, RNA1509_42482} {RNA1509_12772, RNA1509_1406, RNA1509_15139, RNA1509_30164, RNA1509_34338, RNA1509_38982, RNA1509_39853, RNA1509_42482, RNA815_2893}
16. MligTC455_27832 1170 24.38 Mlig455_048328

Neo: Irradiation

Age: -

Region-enriched R5: 1.315/0.00946

 OPLAH 1.764 0.814 - - - - 0.950 Mlig455_048328 {REF} {Length: 9221} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=675.2]; Hydantoinase/oxoprolinase [PF01968.20, score=305.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=151.6]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=26.4]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=795, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=777, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=756, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=762, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=845, Expect=0.0]} {RNA1509_2948} {RNA1310_4544} {RNA815_468}
17. MligTC455_35905 4161 86.69 Mlig455_035334

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.493

 ATP6V1A 1.76 - 0.807 - 0.953 - - Mlig455_035334 {REF} {Length: 3600} {TRANSSPLICED} {Pfam: ATP synthase alpha/beta family, nucleotide-binding domain [PF00006.27, score=353.9]; ATPsynthase alpha/beta subunit N-term extension [PF16886.7, score=141.5]; ATP synthase alpha/beta family, beta-barrel domain [PF02874.25, score=47.5]} {Human: ENSG00000114573, ATP6V1A, ATPase H+ transporting V1 subunit A, [RH, Score=999, Expect=0.0]} {Mouse: ENSMUSG00000052459, Atp6v1a, ATPase, H+ transporting, lysosomal V1 subunit A, [RH, Score=997, Expect=0.0]} {Dmel: FBgn0263598, Vha68-2, Vacuolar H[+] ATPase 68 kDa subunit 2, [RH, Score=1001, Expect=0.0]} {Celegans: WBGene00013025, vha-13, V-type proton ATPase catalytic subunit A, [RH, Score=963, Expect=0.0]} {Smed: dd_Smed_v6_959_0_1, dd_Smed_v6_959_0_1, [RH, Score=985, Expect=0.0]} {RNA1509_1406} {RNA1310_8083.1} {RNA815_2893}
18. MligTC455_18598 756 15.74 Mlig455_063584

Neo: -

Age: -

Region-enriched R4: 1.920/0.00186
Region-enriched R5: 1.402/0.00352

 AGPS 1.753 - - - 0.965 0.788 - Mlig455_063584 {REF} {Length: 3203} {TRANSSPLICED} {Pfam: FAD binding domain [PF01565.25, score=117.2]; FAD linked oxidases, C-terminal domain [PF02913.21, score=113.7]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [RH, Score=692, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [Score=701, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [Score=586, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [Score=594, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [Score=632, Expect=0.0]} {RNA1509_6531} {RNA1310_6470.2} {RNA815_2634}
19. MligTC455_43763 1548 32.26 Mlig455_009134

Neo: -

Age: -

 ETFDH 1.74 0.769 - - 0.971 - - Mlig455_009134 {REF} {Length: 3198} {TRANSSPLICED} {Pfam: Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S [PF05187.15, score=158.2]; FAD dependent oxidoreductase [PF01266.26, score=34.3]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=32.5]; FAD binding domain [PF00890.26, score=32.1]; Thi4 family [PF01946.19, score=31.3]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.3]; FAD-NAD(P)-binding [PF13454.8, score=23.5]; FAD binding domain [PF01494.21, score=19.2]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=18.7]; HI0933-like protein [PF03486.16, score=18.2]} {Human: ENSG00000171503, ETFDH, electron transfer flavoprotein dehydrogenase, [RH, Score=814, Expect=0.0]} {Mouse: ENSMUSG00000027809, Etfdh, electron transferring flavoprotein, dehydrogenase, [RH, Score=829, Expect=0.0]} {Dmel: FBgn0033465, Etf-QO, Electron transfer flavoprotein-ubiquinone oxidoreductase, [RH, Score=753, Expect=0.0]} {Celegans: WBGene00002855, let-721, Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial, [RH, Score=745, Expect=0.0]} {Smed: dd_Smed_v6_3785_0_1, dd_Smed_v6_3785_0_1, [RH, Score=872, Expect=0.0]} {RNA1509_2025, RNA1509_6739} {RNA1310_8787, RNA1509_2025, RNA1509_6739} {RNA1509_2025, RNA1509_6739, RNA815_3614}
20. MligTC455_08324 738 15.37 Mlig455_060730

Neo: Int S/G2/M

Age: Up-Down-Up

 ROMO1 1.729 - 0.778 - - 0.951 - Mlig455_060730 {REF} {Length: 1252} {TRANSSPLICED} {Pfam: Reactive mitochondrial oxygen species modulator 1 [PF10247.11, score=80.5]} {Human: ENSG00000125995, ROMO1, reactive oxygen species modulator 1, [RH, Score=86.7, Expect=3e-23]} {Mouse: ENSMUSG00000067847, Romo1, reactive oxygen species modulator 1, [RH, Score=86.7, Expect=2e-23]} {Dmel: FBgn0036488, CG6878, [RH, Score=87.8, Expect=4e-24]} {Smed: dd_Smed_v6_691_0_1, dd_Smed_v6_691_0_1, [RH, Score=76.6, Expect=6e-20]} {RNA1509_26926} {RNA1310_46637} {RNA815_29226.1}
21. MligTC455_49087 353 7.35 Mlig455_049999

Neo: -

Age: logFC(26M/2M)=0.321

Region-enriched R3: 2.015/0.00143
Region-enriched R5: 1.536/0.00732

 RAC1 1.726 0.758 - - 0.968 - - Mlig455_049999 {REF} {Length: 1762} {Pfam: Ras family [PF00071.24, score=153.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=64.3]; ADP-ribosylation factor family [PF00025.23, score=21.0]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=218, Expect=3e-72]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=215, Expect=2e-71]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=213, Expect=2e-70]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=218, Expect=2e-72]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=214, Expect=5e-71]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=213, Expect=1e-70]} {Dmel: FBgn0010333, Rac1, [Score=218, Expect=6e-73]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=223, Expect=6e-75]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=219, Expect=2e-73]} {RNA1509_17203} {RNA1310_15755.1} {RNA815_8276}
22. MligTC455_40148 859 17.9 Mlig455_017851, Mlig455_047871

Neo: -

Age: -

Region-enriched R4: 2.301/0.00625

 1.716 0.766 - - 0.950 - -

Mlig455_017851 {REF} {Length: 2678} {RNA1509_11917, RNA1509_28007, RNA1509_35856} {RNA1310_13722, RNA1509_11917, RNA1509_28007, RNA1509_35856} {RNA1509_11917, RNA1509_28007, RNA1509_35856, RNA815_5229}

Mlig455_047871 {REF} {Length: 1990} {RNA1509_11917} {RNA1310_13722} {RNA815_5229}
23. MligTC455_49086 274 5.71 Mlig455_011515

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.627

Region-enriched R3: 2.565/0.00416
Region-enriched R5: 2.441/0.00091
Region-enriched R6: 2.339/0.03988

 RAC1 1.697 0.729 - - 0.968 - - Mlig455_011515 {REF} {Length: 1740} {Pfam: Ras family [PF00071.24, score=159.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=69.7]; ADP-ribosylation factor family [PF00025.23, score=26.0]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=221, Expect=2e-73]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=218, Expect=1e-72]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=217, Expect=4e-72]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=221, Expect=1e-73]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=217, Expect=3e-72]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=217, Expect=3e-72]} {Dmel: FBgn0010333, Rac1, [Score=221, Expect=3e-74]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=226, Expect=5e-76]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=223, Expect=6e-75]} {RNA1509_17203} {RNA1310_15755.1} {RNA815_8276}
24. MligTC455_11294 430 8.95 Mlig455_068327

Neo: -

Age: -

 0.983 - - - 0.983 - - Mlig455_068327 {REF} {Length: 1267} {Pfam: Gp5 C-terminal repeat (3 copies) [PF06715.14, score=21.5]} {RNA1509_10965} {RNA1310_87215.1} {RNA815_44952}
25. MligTC455_49382 1312 27.33 Mlig455_026334

Neo: -

Age: -

Region-enriched R5: 1.174/0.00000

 IMMT 0.981 - - - 0.981 - - Mlig455_026334 {REF} {Length: 4063} {Pfam: Mitochondrial inner membrane protein [PF09731.11, score=238.4]} {Human: ENSG00000132305, IMMT, inner membrane mitochondrial protein, [RH, Score=187, Expect=6e-50]} {Mouse: ENSMUSG00000052337, Immt, inner membrane protein, mitochondrial, [RH, Score=188, Expect=2e-50]} {Dmel: FBgn0019960, Mitofilin, [RH, Score=126, Expect=6e-30]} {Celegans: WBGene00020511, immt-1, MICOS complex subunit MIC60-1, [RH, Score=157, Expect=4e-40]} {Smed: dd_Smed_v6_1605_0_1, dd_Smed_v6_1605_0_1, [RH, Score=198, Expect=2e-54]} {RNA1509_29377, RNA1509_40319, RNA1509_49981, RNA1509_6193} {RNA1310_8095, RNA1509_29377, RNA1509_40319, RNA1509_49981, RNA1509_6193} {RNA1509_29377, RNA1509_40319, RNA1509_49981, RNA1509_6193, RNA815_1050.1}
26. MligTC455_12517 587 12.23 Mlig455_023517

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.412

 0.974 - - - - - 0.974 Mlig455_023517 {REF} {Length: 661} {RNA1509_22223} {RNA1310_60769} {RNA815_31256}
27. MligTC455_19520 711 14.82 Mlig455_018524

Neo: -

Age: logFC(26M/2M)=-0.243

 PTDSS2 0.974 - - - 0.974 - - Mlig455_018524 {REF} {Length: 3134} {TRANSSPLICED} {Pfam: Phosphatidyl serine synthase [PF03034.17, score=388.0]} {Human: ENSG00000174915, PTDSS2, phosphatidylserine synthase 2, [Score=480, Expect=7e-167]} {Mouse: ENSMUSG00000025495, Ptdss2, phosphatidylserine synthase 2, [Score=483, Expect=3e-168]} {Dmel: FBgn0037010, CG4825, [Score=269, Expect=1e-84]} {Celegans: WBGene00012095, pssy-2, PhosphatidylSerine SYnthase, [Score=275, Expect=3e-86]} {Smed: dd_Smed_v6_7678_0_1, dd_Smed_v6_7678_0_1, [RH, Score=577, Expect=0.0]} {RNA1509_10186, RNA1509_15443, RNA1509_19161, RNA1509_25562, RNA1509_26982} {RNA1310_5581, RNA1509_10186, RNA1509_15443, RNA1509_19161, RNA1509_25562, RNA1509_26982} {RNA1509_10186, RNA1509_15443, RNA1509_19161, RNA1509_25562, RNA1509_26982, RNA815_3642.1}
28. MligTC455_23055 2998 62.46 Mlig455_004780, Mlig455_004864

Neo: -

Age: Down-Up-Up

 MRPS33 0.974 - - - 0.974 - -

Mlig455_004780 {REF} {Length: 461} {TRANSSPLICED} {Pfam: Mitochondrial ribosomal subunit S27 [PF08293.13, score=46.7]} {Human: ENSG00000090263, MRPS33, mitochondrial ribosomal protein S33, [RH, Score=67.4, Expect=2e-15]} {Mouse: ENSMUSG00000029918, Mrps33, mitochondrial ribosomal protein S33, [RH, Score=67.8, Expect=9e-16]} {Dmel: FBgn0038426, mRpS33, mitochondrial ribosomal protein S33, [RH, Score=75.9, Expect=6e-19]} {Celegans: WBGene00009013, mrps-33, Mitochondrial Ribosomal Protein, Small, [RH, Score=48.9, Expect=2e-08]} {Smed: dd_Smed_v6_3607_0_1, dd_Smed_v6_3607_0_1, [RH, Score=79.7, Expect=1e-20]} {RNA1509_50368, RNA1509_8255} {RNA1310_76540, RNA1509_50368, RNA1509_8255} {RNA1509_50368, RNA1509_8255, RNA815_39196}

Mlig455_004864 {REF} {Length: 461} {TRANSSPLICED} {Pfam: Mitochondrial ribosomal subunit S27 [PF08293.13, score=46.7]} {Human: ENSG00000090263, MRPS33, mitochondrial ribosomal protein S33, [RH, Score=67.4, Expect=2e-15]} {Mouse: ENSMUSG00000029918, Mrps33, mitochondrial ribosomal protein S33, [RH, Score=67.8, Expect=9e-16]} {Dmel: FBgn0038426, mRpS33, mitochondrial ribosomal protein S33, [RH, Score=75.9, Expect=6e-19]} {Celegans: WBGene00009013, mrps-33, Mitochondrial Ribosomal Protein, Small, [RH, Score=48.9, Expect=2e-08]} {Smed: dd_Smed_v6_3607_0_1, dd_Smed_v6_3607_0_1, [RH, Score=79.7, Expect=1e-20]} {RNA1509_50368} {RNA1310_76540} {RNA815_39196}
29. MligTC455_34478 290 6.04 Mlig455_048060

Neo: -

Age: -

 0.971 - - - - - 0.971 Mlig455_048060 {REF} {Length: 682} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_47413} {RNA1310_34257} {RNA815_16356}
30. MligTC455_46673 2511 52.31 Mlig455_001920

Neo: -

Age: -

 WAS 0.967 - - - 0.967 - - Mlig455_001920 {REF} {Length: 3207} {Pfam: WH1 domain [PF00568.25, score=84.7]; P21-Rho-binding domain [PF00786.30, score=27.1]; WH2 motif [PF02205.22, score=19.9]} {Human: ENSG00000015285, WAS, Wiskott-Aldrich syndrome, [RH, Score=138, Expect=7e-35]} {Mouse: ENSMUSG00000029684, Wasl, Wiskott-Aldrich syndrome-like (human), [RH, Score=98.6, Expect=2e-23]} {Dmel: FBgn0024273, WASp, [Score=93.2, Expect=8e-20]} {Smed: dd_Smed_v6_1987_0_1, dd_Smed_v6_1987_0_1, [RH, Score=79.7, Expect=8e-16]} {RNA1509_15317, RNA1509_16868, RNA1509_3515} {RNA1310_20700, RNA1509_15317, RNA1509_16868, RNA1509_3515} {RNA1509_15317, RNA1509_16868, RNA1509_3515, RNA815_12150.1}
31. MligTC455_24146 2470 51.46 Mlig455_060904, Mlig455_069370, Mlig455_069388

Neo: -

Age: logFC(26M/2M)=-0.509

Region-enriched R4: 1.799/0.00434
Region-enriched R3: 1.761/0.00220
Region-enriched R5: 1.603/0.00247

 0.965 - - - 0.965 - -

Mlig455_060904 {REF} {Length: 1171} {Pfam: WW domain-binding protein 1 [PF11669.10, score=23.0]} {RNA1509_12053, RNA1509_23482} {RNA1310_48182, RNA1509_23482} {RNA1509_23482, RNA815_22213}

Mlig455_069370 {REF} {Length: 1132} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}

Mlig455_069388 {REF} {Length: 1155} {Pfam: WW domain-binding protein 1 [PF11669.10, score=23.6]} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}
32. MligTC455_34417 337 7.03 Mlig455_037242

Neo: -

Age: -

 0.965 - - - - - 0.965 Mlig455_037242 {REF} {Length: 1622} {RNA1509_21160} {RNA1310_6052} {RNA815_3316}
33. MligTC455_03703 4461 92.93 Mlig455_031193

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.688

Region-enriched R3: 1.758/0.00057

 0.961 - - - 0.961 - - Mlig455_031193 {REF} {Length: 1805} {RNA1509_14496, RNA1509_17573, RNA1509_2201, RNA1509_23018, RNA1509_27144, RNA1509_28330, RNA1509_40135, RNA1509_5877} {RNA1310_18653, RNA1509_14496, RNA1509_17573, RNA1509_2201, RNA1509_23018, RNA1509_27144, RNA1509_28330, RNA1509_40135, RNA1509_5877} {RNA1509_14496, RNA1509_17573, RNA1509_2201, RNA1509_23018, RNA1509_27144, RNA1509_28330, RNA1509_40135, RNA1509_5877, RNA815_9203.1}
34. MligTC455_39806 2410 50.2 Mlig455_035356, Mlig455_035396

Neo: -

Age: logFC(26M/2M)=0.475

 0.961 - - - 0.961 - -

Mlig455_035356 {REF} {Length: 720} {RNA1509_11746, RNA1509_20417, RNA1509_28901, RNA1509_41712} {RNA1310_32492.1, RNA1509_11746, RNA1509_20417, RNA1509_28901, RNA1509_41712} {RNA1509_11746, RNA1509_20417, RNA1509_28901, RNA1509_41712, RNA815_24107.1}

Mlig455_035396 {REF} {Length: 1846} {RNA1509_41712} {RNA1310_32492.2} {RNA815_24107.1}
35. MligTC455_25935 8899 185.4 Mlig455_005516, Mlig455_016410, Mlig455_021701, Mlig455_023346, Mlig455_023821

Neo: -

Age: -

 0.955 - - - 0.955 - -

Mlig455_005516 {REF} {Length: 936} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5983} {RNA1310_12651.1} {RNA815_12846.1}

Mlig455_016410 {REF} {Length: 1923} {Pfam: FG-GAP repeat [PF01839.25, score=24.8]} {RNA1509_18402, RNA1509_29519} {RNA1310_1040, RNA1509_18402, RNA1509_29519} {RNA1509_18402, RNA1509_29519, RNA815_12503}

Mlig455_021701 {REF} {Length: 932} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5983} {RNA1310_12651.1} {RNA815_12846.1}

Mlig455_023346 {REF} {Length: 926} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5983} {RNA1310_12651.1} {RNA815_12846.1}

Mlig455_023821 {REF} {Length: 928} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_31799, RNA1509_5983} {RNA1310_12651.1, RNA1509_31799} {RNA1509_31799, RNA815_12846.1}
36. MligTC455_52324 4773 99.45 Mlig455_044451

Neo: -

Age: -

 0.952 - - - 0.952 - - Mlig455_044451 {REF} {Length: 582} {TRANSSPLICED} {RNA1509_5438, RNA1509_9148} {RNA1310_59343, RNA1509_5438, RNA1509_9148} {RNA1509_5438, RNA1509_9148, RNA815_30321.1}
37. MligTC455_48968 2833 59.01 Mlig455_068344

Neo: -

Age: -

 0.951 - - - 0.951 - - Mlig455_068344 {REF} {Length: 680} {TRANSSPLICED} {Pfam: Type III secretion system lipoprotein chaperone (YscW) [PF09619.12, score=24.2]} {RNA1509_52356} {RNA1310_19739.1} {RNA815_20380}

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